GREMLIN Database
YJHQ - Uncharacterized N-acetyltransferase YjhQ
UniProt: P39368 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG12559
Length: 181 (163)
Sequences: 2180 (1588)
Seq/√Len: 124.4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
65_F104_G5.3921.00
105_I116_V3.5191.00
85_L101_I3.4221.00
105_I130_F3.0581.00
20_R37_A3.0361.00
23_E86_A2.9321.00
121_H126_P2.6941.00
79_M115_T2.6561.00
9_H54_R2.5341.00
62_H86_A2.1701.00
103_T107_H2.1401.00
22_V59_A2.0701.00
107_H110_L2.0541.00
70_F167_G2.0321.00
89_P92_Q1.9911.00
25_R88_I1.9841.00
98_G127_R1.9051.00
11_T50_S1.8731.00
91_Y94_M1.8341.00
20_R24_T1.8321.00
114_Q159_T1.8281.00
55_Y91_Y1.8261.00
51_L103_T1.8211.00
54_R57_G1.7361.00
103_T106_E1.7351.00
9_H15_D1.7231.00
98_G102_R1.7221.00
52_L59_A1.6681.00
11_T40_L1.6551.00
80_H113_C1.6391.00
63_I104_G1.5721.00
157_S161_Q1.5611.00
82_L101_I1.5571.00
60_V96_V1.5221.00
51_L104_G1.4521.00
23_E62_H1.4451.00
157_S163_M1.4401.00
98_G128_H1.4251.00
87_V96_V1.4131.00
122_A149_H1.3741.00
80_H108_L1.3671.00
119_L171_C1.3361.00
117_F139_Y1.3341.00
126_P154_M1.3141.00
10_I107_H1.2921.00
88_I91_Y1.2481.00
58_K88_I1.2471.00
131_E136_D1.2410.99
82_L118_V1.2400.99
135_G147_E1.2310.99
46_R172_A1.2190.99
53_A96_V1.2180.99
81_I171_C1.2120.99
105_I156_Q1.2090.99
24_T33_A1.2050.99
7_T54_R1.1870.99
109_R156_Q1.1680.99
63_I100_L1.1430.99
82_L116_V1.1280.99
8_F51_L1.1270.99
6_F55_Y1.1260.99
21_E24_T1.1220.99
133_C155_M1.1030.99
68_A169_I1.0980.99
107_H111_M1.0830.99
6_F99_R1.0750.99
23_E36_V1.0730.99
133_C138_G1.0690.98
55_Y60_V1.0650.98
51_L107_H1.0620.98
157_S160_A1.0550.98
101_I128_H1.0520.98
39_L66_T1.0520.98
140_P168_H1.0510.98
141_A145_I1.0450.98
119_L153_W1.0420.98
42_D172_A1.0370.98
81_I175_D1.0370.98
61_G100_L1.0370.98
70_F79_M1.0100.98
30_S33_A0.9880.97
97_G124_Y0.9880.97
17_S21_E0.9650.97
20_R34_D0.9610.97
171_C175_D0.9560.97
84_P125_Y0.9490.97
70_F165_L0.9430.97
121_H149_H0.9370.97
42_D174_P0.9370.97
68_A79_M0.9360.96
35_L83_A0.9330.96
15_D54_R0.9310.96
106_E109_R0.9280.96
35_L141_A0.9260.96
60_V91_Y0.9230.96
121_H154_M0.9220.96
81_I153_W0.9120.96
118_V154_M0.9030.96
157_S162_P0.9030.96
20_R33_A0.9020.96
63_I85_L0.9000.96
67_R78_L0.8930.95
99_R102_R0.8920.95
102_R106_E0.8760.95
46_R111_M0.8730.95
153_W171_C0.8720.95
65_F82_L0.8710.95
29_F33_A0.8600.94
24_T28_G0.8540.94
55_Y58_K0.8490.94
128_H156_Q0.8290.93
131_E157_S0.8220.93
22_V88_I0.8120.93
24_T31_K0.8090.92
81_I117_F0.8090.92
71_K168_H0.8080.92
58_K90_E0.8060.92
58_K91_Y0.7960.92
9_H52_L0.7920.92
106_E110_L0.7920.92
66_T149_H0.7900.91
53_A87_V0.7890.91
147_E154_M0.7840.91
26_A89_P0.7820.91
68_A81_I0.7810.91
93_G124_Y0.7760.91
19_I45_A0.7760.91
25_R90_E0.7750.91
51_L100_L0.7740.91
124_Y128_H0.7740.91
18_D58_K0.7730.91
79_M117_F0.7730.91
87_V124_Y0.7660.90
73_E166_T0.7650.90
64_L83_A0.7600.90
27_F84_P0.7590.90
47_P64_L0.7580.90
65_F108_L0.7540.89
61_G87_V0.7510.89
25_R89_P0.7500.89
34_D38_S0.7490.89
67_R113_C0.7450.89
49_L111_M0.7420.89
46_R113_C0.7290.88
108_L139_Y0.7290.88
137_K155_M0.7270.88
46_R108_L0.7220.87
51_L61_G0.7180.87
10_I51_L0.7180.87
80_H116_V0.7170.87
131_E137_K0.7160.87
83_A143_Y0.7150.87
114_Q162_P0.7150.87
72_G123_T0.7100.86
45_A64_L0.7020.86
126_P132_P0.6990.86
153_W169_I0.6980.86
85_L100_L0.6940.85
92_Q125_Y0.6920.85
46_R49_L0.6880.85
32_E175_D0.6870.85
124_Y127_R0.6870.85
102_R156_Q0.6820.84
102_R109_R0.6810.84
108_L116_V0.6770.84
71_K170_R0.6750.84
118_V153_W0.6740.83
45_A50_S0.6730.83
49_L108_L0.6630.82
65_F118_V0.6610.82
48_A67_R0.6600.82
23_E50_S0.6580.82
53_A61_G0.6570.82
30_S34_D0.6540.82
109_R159_T0.6530.82
122_A126_P0.6510.81
63_I101_I0.6480.81
21_E25_R0.6470.81
153_W175_D0.6440.81
119_L145_I0.6440.81
115_T163_M0.6430.81
16_A40_L0.6390.80
164_T169_I0.6380.80
46_R80_H0.6340.80
50_S62_H0.6310.79
69_T170_R0.6310.79
32_E35_L0.6290.79
141_A153_W0.6210.78
83_A118_V0.6160.78
81_I125_Y0.6140.77
160_A163_M0.6110.77
70_F115_T0.6110.77
119_L141_A0.6070.77
55_Y94_M0.6060.76
72_G77_P0.6040.76
102_R128_H0.6010.76
119_L169_I0.5990.76
142_P168_H0.5970.75
22_V26_A0.5920.75
28_G33_A0.5900.75
35_L175_D0.5900.75
27_F35_L0.5870.74
65_F116_V0.5830.74
85_L97_G0.5800.73
109_R158_L0.5800.73
120_G125_Y0.5770.73
32_E119_L0.5750.73
27_F92_Q0.5730.72
121_H124_Y0.5730.72
139_Y169_I0.5710.72
121_H125_Y0.5700.72
24_T30_S0.5670.72
43_E47_P0.5630.71
12_D15_D0.5620.71
39_L174_P0.5600.71
23_E85_L0.5580.70
47_P79_M0.5530.70
116_V130_F0.5480.69
119_L154_M0.5480.69
136_D140_P0.5460.69
146_P149_H0.5420.68
12_D110_L0.5420.68
159_T162_P0.5400.68
83_A146_P0.5390.68
95_G99_R0.5370.68
16_A45_A0.5350.67
145_I153_W0.5330.67
25_R28_G0.5320.67
9_H59_A0.5310.67
54_R59_A0.5290.66
18_D59_A0.5270.66
18_D21_E0.5270.66
118_V156_Q0.5220.65
31_K63_I0.5180.65
28_G34_D0.5160.65
40_L108_L0.5150.64
17_S20_R0.5140.64
61_G131_E0.5130.64
32_E36_V0.5120.64
8_F100_L0.5100.64
16_A19_I0.5090.63
157_S164_T0.5060.63
83_A119_L0.5030.63
14_S166_T0.5000.62
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4zbgA 1 0.8232 99.9 0.568 Contact Map
4rs2A 1 0.9558 99.9 0.608 Contact Map
3r1kA 4 0.9558 99.7 0.672 Contact Map
2hv2A 4 0.9669 99.7 0.674 Contact Map
3sxnA 4 0.9724 99.7 0.675 Contact Map
2i00A 4 0.9613 99.7 0.677 Contact Map
1kuxA 1 0.8398 99.7 0.679 Contact Map
1cjwA 1 0.8398 99.7 0.68 Contact Map
3te4A 1 0.8232 99.7 0.681 Contact Map
2reeA 1 0.8287 99.7 0.681 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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