GREMLIN Database
YJHP - Uncharacterized protein YjhP
UniProt: P39367 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG12558
Length: 248 (209)
Sequences: 17044 (12983)
Seq/√Len: 898.0

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
39_R61_T3.4291.00
127_A179_Y2.7461.00
72_T90_F2.5961.00
69_S92_H2.5471.00
75_A90_F2.5431.00
63_T104_C2.5261.00
45_S64_G2.5131.00
72_T76_K2.5131.00
61_T89_H2.4971.00
125_L128_Q2.4571.00
51_L62_G2.4301.00
56_R82_L2.3691.00
126_L136_M2.3351.00
63_T91_I2.3161.00
41_L104_C2.3111.00
65_I93_N2.2201.00
69_S73_A2.2161.00
105_D131_K2.2061.00
52_C79_A2.0881.00
130_L134_G2.0661.00
38_T106_V2.0531.00
107_A130_L2.0491.00
107_A126_L2.0371.00
72_T92_H2.0351.00
44_G112_A2.0141.00
74_Q77_R1.9691.00
125_L129_S1.9061.00
35_K38_T1.9041.00
109_C112_A1.7931.00
52_C78_R1.7651.00
120_A176_D1.7571.00
118_G121_G1.7521.00
26_A53_T1.7441.00
66_D72_T1.7381.00
39_R63_T1.7151.00
130_L136_M1.7141.00
120_A124_E1.6981.00
40_I54_W1.6901.00
63_T89_H1.5741.00
39_R131_K1.5551.00
43_L95_A1.5391.00
77_R81_E1.5251.00
43_L126_L1.5181.00
195_Y198_A1.5121.00
95_A116_A1.5041.00
64_G90_F1.4881.00
206_W209_A1.4811.00
79_A90_F1.4731.00
93_N99_V1.4651.00
45_S51_L1.4551.00
34_M38_T1.4241.00
112_A116_A1.4191.00
194_R198_A1.3951.00
100_A103_K1.3831.00
80_E85_S1.3821.00
51_L64_G1.3791.00
40_I106_V1.3511.00
73_A76_K1.3411.00
121_G124_E1.3321.00
79_A88_V1.3311.00
120_A173_A1.3161.00
78_R81_E1.3141.00
166_T169_G1.3071.00
155_A159_S1.3051.00
45_S75_A1.3041.00
39_R104_C1.2891.00
50_M108_A1.2771.00
27_T30_R1.2691.00
94_D97_G1.2681.00
195_Y200_W1.2661.00
98_Y129_S1.2561.00
70_L73_A1.2531.00
116_A122_A1.2521.00
130_L179_Y1.2461.00
44_G109_C1.2341.00
156_C159_S1.2311.00
41_L107_A1.2231.00
122_A126_L1.2021.00
26_A30_R1.2001.00
101_N128_Q1.1941.00
73_A77_R1.1771.00
16_I19_P1.1771.00
53_T57_D1.1571.00
31_V185_V1.1541.00
77_R80_E1.1441.00
119_F173_A1.1421.00
172_G176_D1.1371.00
53_T56_R1.1331.00
65_I98_Y1.1271.00
98_Y125_L1.1171.00
95_A112_A1.1151.00
212_D215_F1.1111.00
52_C82_L1.1091.00
171_V175_D1.1021.00
200_W204_R1.1001.00
55_A87_R1.0971.00
107_A129_S1.0711.00
42_D62_G1.0601.00
78_R82_L1.0511.00
123_E174_F1.0491.00
39_R105_D1.0471.00
27_T31_V1.0441.00
67_M94_D1.0421.00
66_D71_F1.0411.00
216_A220_R1.0211.00
217_A220_R1.0161.00
31_V183_E1.0151.00
42_D64_G1.0041.00
64_G75_A1.0041.00
198_A201_L1.0001.00
74_Q78_R0.9991.00
126_L130_L0.9941.00
196_E202_T0.9931.00
217_A221_A0.9831.00
113_T140_E0.9801.00
38_T60_I0.9751.00
50_M110_V0.9631.00
153_A157_G0.9561.00
39_R103_K0.9521.00
167_L171_V0.9471.00
36_P59_G0.9441.00
150_E153_A0.9381.00
101_N125_L0.9371.00
202_T206_W0.9371.00
172_G175_D0.9331.00
198_A202_T0.9311.00
196_E200_W0.9311.00
213_D216_A0.9291.00
121_G125_L0.9291.00
15_R47_S0.9191.00
28_L137_L0.9171.00
124_E177_L0.9141.00
21_T24_K0.9101.00
215_F218_E0.9081.00
47_S71_F0.9011.00
38_T105_D0.9011.00
171_V184_M0.8981.00
40_I108_A0.8941.00
54_W108_A0.8931.00
111_G114_W0.8871.00
96_A116_A0.8861.00
193_D197_A0.8841.00
195_Y199_K0.8801.00
41_L129_S0.8801.00
99_V125_L0.8781.00
93_N98_Y0.8771.00
103_K131_K0.8721.00
65_I91_I0.8711.00
51_L90_F0.8631.00
150_E154_Q0.8601.00
127_A177_L0.8571.00
76_K80_E0.8501.00
113_T116_A0.8421.00
203_M207_L0.8321.00
26_A57_D0.8281.00
218_E222_E0.8241.00
215_F219_V0.8171.00
50_M54_W0.8071.00
32_L137_L0.8071.00
45_S66_D0.8021.00
68_S71_F0.7991.00
27_T185_V0.7981.00
48_G75_A0.7981.00
33_R135_I0.7971.00
146_L149_T0.7961.00
169_G172_G0.7951.00
52_C56_R0.7901.00
207_L211_P0.7891.00
219_V223_L0.7861.00
22_E26_A0.7831.00
49_E53_T0.7811.00
168_P172_G0.7791.00
51_L88_V0.7781.00
14_H17_H0.7761.00
220_R223_L0.7701.00
124_E128_Q0.7661.00
153_A156_C0.7631.00
79_A84_V0.7621.00
212_D216_A0.7611.00
34_M37_G0.7601.00
55_A88_V0.7561.00
120_A177_L0.7561.00
154_Q157_G0.7541.00
111_G139_G0.7541.00
28_L110_V0.7541.00
211_P215_F0.7531.00
23_E26_A0.7521.00
151_E154_Q0.7471.00
25_Y50_M0.7451.00
113_T123_E0.7251.00
106_V135_I0.7231.00
48_G90_F0.7221.00
110_V139_G0.7221.00
163_D169_G0.7221.00
34_M60_I0.7171.00
114_W140_E0.7041.00
194_R197_A0.7011.00
127_A178_G0.6971.00
199_K202_T0.6961.00
37_G60_I0.6881.00
197_A200_W0.6851.00
103_K129_S0.6841.00
109_C138_I0.6821.00
214_D218_E0.6821.00
42_D108_A0.6791.00
219_V222_E0.6791.00
76_K89_H0.6771.00
174_F177_L0.6741.00
27_T187_A0.6711.00
193_D202_T0.6681.00
198_A203_M0.6601.00
168_P171_V0.6571.00
66_D92_H0.6541.00
45_S65_I0.6511.00
111_G115_I0.6511.00
216_A223_L0.6501.00
111_G141_P0.6481.00
30_R57_D0.6471.00
80_E87_R0.6431.00
29_G54_W0.6411.00
70_L74_Q0.6401.00
96_A121_G0.6401.00
195_Y203_M0.6401.00
19_P22_E0.6391.00
201_L205_R0.6381.00
42_D65_I0.6361.00
100_A129_S0.6341.00
95_A122_A0.6331.00
45_S90_F0.6331.00
64_G88_V0.6321.00
181_V184_M0.6311.00
196_E201_L0.6311.00
17_H20_F0.6291.00
80_E83_G0.6281.00
204_R207_L0.6271.00
96_A117_G0.6271.00
84_V87_R0.6261.00
93_N97_G0.6221.00
202_T205_R0.6221.00
69_S76_K0.6211.00
197_A201_L0.6191.00
29_G53_T0.6191.00
155_A158_V0.6181.00
67_M92_H0.6181.00
61_T87_R0.6151.00
113_T138_I0.6151.00
204_R208_E0.6061.00
193_D200_W0.6031.00
201_L204_R0.6011.00
23_E27_T0.6001.00
128_Q131_K0.5981.00
123_E170_L0.5941.00
113_T119_F0.5931.00
215_F222_E0.5931.00
152_I156_C0.5921.00
19_P23_E0.5911.00
101_N129_S0.5901.00
109_C126_L0.5891.00
195_Y201_L0.5841.00
170_L174_F0.5841.00
97_G121_G0.5781.00
113_T122_A0.5751.00
196_E199_K0.5741.00
213_D217_A0.5691.00
169_G173_A0.5681.00
193_D196_E0.5681.00
216_A219_V0.5651.00
97_G125_L0.5631.00
208_E211_P0.5621.00
40_I62_G0.5601.00
104_C129_S0.5581.00
123_E177_L0.5571.00
167_L186_L0.5551.00
207_L210_N0.5551.00
136_M179_Y0.5541.00
54_W106_V0.5491.00
15_R78_R0.5461.00
18_N22_E0.5451.00
159_S222_E0.5451.00
76_K90_F0.5451.00
99_V129_S0.5431.00
173_A176_D0.5431.00
182_V186_L0.5421.00
52_C88_V0.5351.00
38_T135_I0.5351.00
106_V137_L0.5351.00
99_V128_Q0.5331.00
189_Q192_W0.5321.00
140_E170_L0.5321.00
96_A118_G0.5301.00
123_E173_A0.5291.00
96_A122_A0.5281.00
43_L107_A0.5271.00
25_Y53_T0.5251.00
37_G59_G0.5231.00
194_R202_T0.5231.00
14_H20_F0.5201.00
161_T165_L0.5201.00
162_S165_L0.5181.00
158_V222_E0.5161.00
106_V134_G0.5151.00
205_R208_E0.5141.00
165_L169_G0.5121.00
44_G116_A0.5121.00
39_R102_E0.5121.00
15_R19_P0.5121.00
95_A98_Y0.5081.00
115_I140_E0.5061.00
43_L65_I0.5051.00
21_T25_Y0.5041.00
38_T131_K0.5031.00
153_A159_S0.5021.00
40_I60_I0.5011.00
115_I141_P0.5001.00
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
5bp7A 3 1 100 0.34 Contact Map
2o57A 2 0.9798 100 0.359 Contact Map
4pneA 2 0.9556 100 0.369 Contact Map
2p35A 2 0.9194 100 0.372 Contact Map
3ccfA 1 0.9073 100 0.381 Contact Map
2yqzA 1 0.9677 100 0.384 Contact Map
3busA 1 0.9153 100 0.385 Contact Map
4kriA 1 0.9677 100 0.407 Contact Map
4ineA 2 0.9758 100 0.407 Contact Map
2fk8A 1 0.9476 100 0.408 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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