GREMLIN Database
SGCQ - Putative sgc region protein SgcQ
UniProt: P39364 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG12555
Length: 268 (253)
Sequences: 559 (368)
Seq/√Len: 23.1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
52_G256_V4.3811.00
206_K214_V3.2981.00
171_C204_R3.2601.00
83_I96_V3.2591.00
206_K233_D3.2351.00
260_M263_V3.1641.00
155_F183_P3.0351.00
14_V54_V2.8280.99
244_D249_N2.6790.99
35_M78_A2.6770.99
107_D142_H2.6320.99
8_I13_A2.5450.99
85_Q88_S2.5040.98
174_A209_V2.4380.98
14_V235_C2.3830.98
45_D251_V2.3730.98
21_R42_A2.3690.98
81_R85_Q2.3200.97
187_C217_N2.3110.97
54_V256_V2.2440.97
157_I174_A2.2430.97
216_A220_V2.1990.96
54_V241_F2.1960.96
154_L185_A2.1780.96
20_L42_A2.1710.96
60_S160_E2.1390.96
160_E218_T2.0570.95
60_S218_T2.0400.94
14_V260_M2.0250.94
69_T133_D2.0080.94
48_A52_G1.9710.93
36_N40_D1.9290.92
222_L240_T1.9230.92
100_W127_S1.8260.90
59_F94_F1.7600.88
121_F139_T1.7550.88
99_L119_E1.6930.86
40_D44_D1.6810.86
148_A151_V1.6670.85
119_E159_P1.6350.84
146_I151_V1.6270.84
245_G255_R1.6010.83
135_N138_E1.5900.83
98_V108_L1.5820.82
46_L86_L1.5780.82
41_K44_D1.5550.81
226_E262_K1.5480.81
101_D104_A1.5040.79
58_M116_F1.4830.78
59_F83_I1.4790.78
77_A111_A1.4690.77
26_D64_S1.4660.77
122_T177_T1.4540.76
28_S182_H1.4520.76
60_S193_A1.4410.76
100_W119_E1.4350.75
21_R41_K1.4180.75
51_N253_Q1.4000.74
60_S159_P1.3970.73
44_D250_F1.3970.73
46_L57_V1.3880.73
100_W129_F1.3880.73
30_D37_W1.3820.73
45_D48_A1.3810.73
45_D63_F1.3590.71
246_V249_N1.3580.71
60_S161_A1.3480.71
43_W86_L1.3330.70
125_Y162_A1.3330.70
87_M94_F1.3300.70
81_R84_G1.3220.69
110_M147_G1.3150.69
56_A116_F1.3120.69
159_P193_A1.3030.68
203_K207_E1.3030.68
175_K254_A1.3020.68
17_M49_L1.2910.67
241_F260_M1.2830.67
43_W90_I1.2810.67
67_Y119_E1.2780.66
174_A205_V1.2390.64
129_F180_N1.2350.64
159_P218_T1.2330.64
17_M58_M1.2240.63
214_V232_A1.2080.62
110_M148_A1.1990.61
64_S107_D1.1920.61
209_V212_T1.1830.60
44_D47_M1.1810.60
98_V101_D1.1750.60
257_S261_E1.1620.59
27_P141_R1.1540.58
156_N218_T1.1430.58
161_A218_T1.1400.57
160_E193_A1.1330.57
83_I112_T1.1320.57
243_K249_N1.1300.57
19_H24_P1.1300.57
76_T80_A1.1270.57
15_I56_A1.1240.56
100_W180_N1.1140.56
154_L236_V1.1020.55
251_V256_V1.1000.55
97_N119_E1.0930.54
42_A82_I1.0790.53
25_G74_E1.0670.52
170_I174_A1.0640.52
45_D244_D1.0570.52
156_N217_N1.0560.52
174_A208_T1.0480.51
101_D120_I1.0450.51
220_V225_V1.0450.51
119_E129_F1.0380.50
103_V138_E1.0360.50
196_R224_N1.0310.50
16_A19_H1.0280.50
25_G238_A1.0280.50
243_K250_F1.0180.49
156_N161_A1.0070.48
54_V260_M1.0070.48
125_Y158_V1.0070.48
118_R130_G1.0060.48
47_M51_N1.0010.48
80_A84_G0.9990.48
243_K252_D0.9970.47
99_L128_D0.9920.47
17_M232_A0.9890.47
137_G141_R0.9880.47
60_S156_N0.9760.46
124_A134_T0.9670.45
50_Q92_I0.9660.45
64_S161_A0.9560.45
241_F256_V0.9550.45
60_S187_C0.9530.44
161_A193_A0.9500.44
237_T259_F0.9490.44
158_V162_A0.9450.44
85_Q240_T0.9410.44
61_N66_P0.9390.43
132_W155_F0.9390.43
120_I129_F0.9340.43
82_I263_V0.9320.43
257_S264_H0.9230.42
12_K233_D0.9140.42
29_F147_G0.9140.42
124_A131_V0.9130.42
40_D47_M0.9090.41
119_E127_S0.9090.41
123_G173_I0.9030.41
197_T228_Q0.9000.41
185_A228_Q0.8990.41
160_E187_C0.8940.40
153_T237_T0.8910.40
249_N255_R0.8880.40
68_L72_R0.8840.40
88_S215_L0.8840.40
170_I205_V0.8830.40
50_Q90_I0.8780.39
39_I85_Q0.8780.39
12_K29_F0.8780.39
96_V109_A0.8770.39
43_W89_D0.8750.39
222_L262_K0.8740.39
49_L232_A0.8730.39
18_C42_A0.8580.38
63_F247_F0.8570.38
21_R59_F0.8570.38
86_L89_D0.8540.38
191_L205_V0.8520.38
205_V238_A0.8510.38
42_A59_F0.8470.37
102_P165_L0.8460.37
220_V235_C0.8440.37
258_Q261_E0.8430.37
108_L237_T0.8420.37
228_Q235_C0.8410.37
51_N152_K0.8380.37
47_M90_I0.8310.36
215_L239_T0.8280.36
47_M57_V0.8280.36
99_L193_A0.8250.36
12_K15_I0.8230.36
143_Q239_T0.8230.36
120_I127_S0.8220.36
15_I93_P0.8210.36
62_E125_Y0.8200.36
226_E257_S0.8180.35
178_V212_T0.8110.35
45_D52_G0.8070.35
254_A258_Q0.8070.35
99_L202_L0.8020.34
91_R117_I0.7970.34
115_K150_E0.7960.34
21_R38_V0.7960.34
102_P139_T0.7950.34
50_Q206_K0.7880.34
17_M236_V0.7850.33
97_N100_W0.7840.33
101_D124_A0.7820.33
142_H146_I0.7790.33
193_A218_T0.7780.33
164_Y247_F0.7750.33
77_A106_F0.7740.33
156_N160_E0.7740.33
140_I153_T0.7700.32
99_L236_V0.7700.32
109_A151_V0.7690.32
14_V39_I0.7670.32
110_M150_E0.7660.32
97_N159_P0.7650.32
73_P76_T0.7630.32
12_K263_V0.7630.32
17_M189_S0.7570.32
156_N187_C0.7570.32
43_W46_L0.7560.32
225_V229_L0.7560.32
144_H147_G0.7500.31
13_A233_D0.7480.31
196_R227_E0.7450.31
57_V92_I0.7450.31
44_D87_M0.7440.31
73_P104_A0.7440.31
226_E261_E0.7430.31
67_Y159_P0.7420.31
117_I236_V0.7400.31
40_D207_E0.7380.31
87_M225_V0.7380.31
57_V257_S0.7350.30
208_T215_L0.7330.30
7_V224_N0.7290.30
227_E261_E0.7290.30
252_D259_F0.7270.30
49_L241_F0.7240.30
47_M87_M0.7240.30
60_S119_E0.7240.30
119_E160_E0.7200.29
81_R111_A0.7160.29
197_T220_V0.7150.29
55_D233_D0.7130.29
7_V22_A0.7120.29
119_E155_F0.7120.29
35_M82_I0.7070.29
223_E258_Q0.7060.29
120_I123_G0.7050.29
122_T189_S0.7040.29
189_S220_V0.7030.28
30_D58_M0.7000.28
83_I94_F0.7000.28
173_I177_T0.6950.28
119_E134_T0.6930.28
10_T13_A0.6930.28
45_D111_A0.6920.28
123_G128_D0.6910.28
54_V57_V0.6890.28
16_A49_L0.6870.28
70_K117_I0.6860.28
129_F164_Y0.6850.27
13_A246_V0.6840.27
60_S105_S0.6840.27
22_A145_R0.6800.27
170_I213_V0.6780.27
39_I82_I0.6770.27
60_S217_N0.6760.27
75_T185_A0.6740.27
58_M230_S0.6720.27
159_P176_S0.6710.27
160_E217_N0.6710.27
22_A28_S0.6710.27
222_L258_Q0.6700.27
99_L129_F0.6670.26
14_V241_F0.6650.26
72_R164_Y0.6650.26
32_Q37_W0.6620.26
108_L171_C0.6560.26
163_V169_D0.6540.26
14_V185_A0.6530.26
156_N159_P0.6490.26
215_L234_G0.6470.25
61_N242_K0.6450.25
119_E218_T0.6450.25
174_A188_V0.6420.25
199_S223_E0.6410.25
123_G129_F0.6410.25
252_D256_V0.6390.25
17_M25_G0.6380.25
220_V228_Q0.6380.25
14_V246_V0.6360.25
127_S180_N0.6350.25
41_K177_T0.6340.25
126_A162_A0.6330.25
15_I58_M0.6330.25
100_W159_P0.6320.25
229_L235_C0.6290.24
178_V211_D0.6240.24
45_D249_N0.6230.24
164_Y180_N0.6230.24
9_G56_A0.6210.24
194_G218_T0.6200.24
13_A20_L0.6170.24
222_L259_F0.6160.24
119_E128_D0.6150.24
17_M238_A0.6130.24
43_W117_I0.6120.24
45_D224_N0.6050.23
72_R142_H0.6020.23
38_V82_I0.6010.23
155_F218_T0.6000.23
166_G176_S0.5980.23
140_I241_F0.5980.23
11_E51_N0.5870.22
189_S217_N0.5860.22
50_Q91_R0.5860.22
123_G164_Y0.5860.22
222_L226_E0.5840.22
119_E156_N0.5830.22
134_T164_Y0.5820.22
112_T188_V0.5800.22
74_E107_D0.5790.22
18_C88_S0.5790.22
66_P190_G0.5790.22
86_L113_G0.5790.22
24_P245_G0.5780.22
22_A42_A0.5770.22
129_F161_A0.5760.22
58_M136_V0.5740.22
120_I134_T0.5730.22
49_L54_V0.5690.22
117_I139_T0.5650.21
88_S186_L0.5610.21
58_M135_N0.5610.21
159_P187_C0.5590.21
126_A153_T0.5580.21
94_F222_L0.5570.21
58_M120_I0.5560.21
22_A191_L0.5550.21
62_E180_N0.5540.21
47_M261_E0.5510.21
207_E254_A0.5510.21
69_T119_E0.5500.21
239_T247_F0.5460.20
199_S233_D0.5440.20
22_A214_V0.5430.20
176_S180_N0.5430.20
119_E180_N0.5420.20
198_D233_D0.5410.20
131_V196_R0.5350.20
17_M119_E0.5330.20
196_R254_A0.5310.20
185_A206_K0.5310.20
113_G143_Q0.5300.20
57_V90_I0.5290.20
197_T202_L0.5260.20
78_A253_Q0.5250.20
73_P192_T0.5250.20
70_K264_H0.5240.19
13_A93_P0.5220.19
42_A94_F0.5210.19
24_P242_K0.5210.19
71_V76_T0.5170.19
128_D139_T0.5150.19
161_A180_N0.5150.19
100_W156_N0.5140.19
127_S134_T0.5130.19
62_E120_I0.5120.19
58_M222_L0.5110.19
64_S193_A0.5110.19
119_E136_V0.5110.19
143_Q257_S0.5100.19
92_I216_A0.5100.19
109_A236_V0.5090.19
76_T213_V0.5080.19
198_D244_D0.5080.19
19_H27_P0.5060.19
105_S177_T0.5050.19
96_V240_T0.5040.19
99_L180_N0.5040.19
70_K73_P0.5030.19
26_D75_T0.5030.19
62_E97_N0.5010.18
205_V214_V0.5000.18
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2ekcA 1 0.8507 99.8 0.793 Contact Map
1ujpA 1 0.7761 99.8 0.793 Contact Map
3thaA 2 0.8321 99.8 0.798 Contact Map
3vndA 3 0.8321 99.8 0.798 Contact Map
3navA 2 0.8433 99.8 0.799 Contact Map
4ht3A 1 0.8657 99.8 0.8 Contact Map
4r9xA 2 0.7761 99.8 0.805 Contact Map
1geqA 1 0.8172 99.7 0.813 Contact Map
2yw3A 4 0.7351 99.7 0.815 Contact Map
1rd5A 6 0.8657 99.7 0.817 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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