GREMLIN Database
SGCA - Putative phosphotransferase IIA component SgcA
UniProt: P39363 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG12554
Length: 143 (135)
Sequences: 6787 (5214)
Seq/√Len: 448.8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
95_W129_G3.3401.00
5_I135_D2.5361.00
133_T136_A2.2521.00
22_E39_V2.1991.00
25_T39_V2.1401.00
26_R30_A2.0961.00
35_Q71_N2.0361.00
37_C69_G2.0321.00
126_T130_N2.0131.00
80_L97_L1.9701.00
24_A99_C1.9361.00
14_A23_I1.9011.00
9_Q27_P1.8811.00
42_I99_C1.8721.00
16_D19_Q1.8601.00
33_A72_Y1.8481.00
13_K81_R1.7861.00
7_W31_Y1.7611.00
11_Q81_R1.7331.00
83_P95_W1.7111.00
29_V34_A1.6911.00
14_A20_A1.6901.00
33_A74_Q1.6491.00
40_N44_E1.6481.00
11_Q79_T1.6431.00
6_K31_Y1.5961.00
74_Q101_S1.5931.00
12_R78_T1.5561.00
18_R47_L1.5501.00
24_A78_T1.5501.00
70_A101_S1.5501.00
132_S136_A1.5151.00
73_N103_T1.4751.00
15_T19_Q1.4611.00
38_Y101_S1.4331.00
5_I138_F1.4091.00
131_A137_L1.3971.00
44_E47_L1.3871.00
22_E43_I1.3551.00
20_A97_L1.3441.00
58_G95_W1.3421.00
41_G64_A1.3321.00
41_G44_E1.3241.00
67_E104_D1.3091.00
135_D139_A1.3081.00
80_L83_P1.2961.00
9_Q23_I1.2911.00
10_A79_T1.2741.00
21_V42_I1.2431.00
27_P30_A1.2381.00
57_P125_L1.2351.00
18_R43_I1.2261.00
35_Q69_G1.1981.00
94_V97_L1.1681.00
44_E48_N1.1671.00
27_P31_Y1.1671.00
52_Y89_E1.1671.00
125_L129_G1.1611.00
77_I137_L1.1571.00
85_A93_P1.1521.00
86_F97_L1.1301.00
131_A136_A1.1301.00
25_T42_I1.1291.00
12_R23_I1.0881.00
9_Q12_R1.0481.00
17_W87_G1.0421.00
5_I134_D1.0351.00
14_A80_L1.0171.00
4_D7_W1.0111.00
66_P69_G1.0051.00
96_L129_G1.0051.00
75_V111_T1.0021.00
127_A140_L1.0011.00
18_R22_E1.0001.00
23_I27_P0.9911.00
39_V43_I0.9871.00
85_A88_N0.9831.00
13_K82_T0.9761.00
136_A139_A0.9571.00
118_F124_R0.9541.00
131_A140_L0.9511.00
19_Q22_E0.9501.00
113_Q117_Q0.9431.00
34_A38_Y0.9421.00
46_T51_P0.9381.00
134_D138_F0.9321.00
10_A137_L0.9281.00
79_T137_L0.9141.00
25_T99_C0.9131.00
77_I96_L0.9071.00
28_L76_S0.9021.00
73_N102_A0.8951.00
28_L101_S0.8951.00
29_V36_P0.8911.00
121_S124_R0.8871.00
43_I47_L0.8861.00
27_P76_S0.8751.00
32_G71_N0.8681.00
26_R29_V0.8681.00
127_A130_N0.8591.00
116_S120_D0.8591.00
80_L95_W0.8551.00
20_A80_L0.8511.00
19_Q23_I0.8511.00
22_E40_N0.8501.00
29_V39_V0.8471.00
21_V39_V0.8421.00
23_I26_R0.8301.00
8_V137_L0.8261.00
8_V134_D0.8191.00
83_P93_P0.8161.00
73_N107_A0.8141.00
79_T96_L0.8091.00
17_W46_T0.8071.00
36_P40_N0.8061.00
124_R140_L0.8061.00
102_A111_T0.8051.00
15_T82_T0.8031.00
78_T99_C0.7971.00
38_Y42_I0.7891.00
113_Q116_S0.7671.00
61_L112_I0.7671.00
104_D107_A0.7631.00
37_C41_G0.7621.00
23_I78_T0.7501.00
10_A134_D0.7341.00
41_G66_P0.7271.00
108_H112_I0.7261.00
7_W33_A0.7241.00
41_G69_G0.7171.00
4_D72_Y0.7161.00
115_I119_I0.7141.00
80_L84_V0.6991.00
26_R39_V0.6981.00
82_T95_W0.6961.00
24_A76_S0.6941.00
118_F141_V0.6941.00
57_P92_D0.6911.00
20_A84_V0.6891.00
77_I98_L0.6751.00
22_E26_R0.6751.00
87_G92_D0.6741.00
45_N62_P0.6641.00
127_A136_A0.6551.00
58_G129_G0.6551.00
52_Y90_E0.6501.00
12_R81_R0.6491.00
28_L74_Q0.6461.00
8_V138_F0.6461.00
56_A59_I0.6450.99
76_S99_C0.6390.99
14_A78_T0.6380.99
4_D31_Y0.6380.99
122_P126_T0.6350.99
59_I119_I0.6300.99
21_V43_I0.6280.99
134_D137_L0.6230.99
9_Q134_D0.6220.99
102_A108_H0.6190.99
13_K23_I0.6180.99
55_I102_A0.6110.99
109_I113_Q0.6100.99
56_A94_V0.6050.99
75_V98_L0.6030.99
116_S119_I0.6030.99
98_L115_I0.6010.99
60_A94_V0.5990.99
123_Q127_A0.5980.99
38_Y99_C0.5970.99
52_Y88_N0.5930.99
114_R118_F0.5930.99
28_L38_Y0.5920.99
17_W21_V0.5860.99
25_T29_V0.5850.99
11_Q132_S0.5730.99
76_S101_S0.5710.99
124_R127_A0.5710.99
57_P122_P0.5680.99
45_N49_W0.5680.99
59_I125_L0.5660.99
4_D33_A0.5630.99
22_E36_P0.5590.99
128_V137_L0.5580.99
117_Q121_S0.5540.98
66_P70_A0.5490.98
110_L117_Q0.5490.98
127_A131_A0.5470.98
28_L34_A0.5460.98
45_N51_P0.5430.98
37_C40_N0.5370.98
55_I116_S0.5300.98
38_Y74_Q0.5290.98
52_Y86_F0.5260.98
88_N93_P0.5210.98
75_V115_I0.5190.98
124_R141_V0.5130.98
24_A97_L0.5130.98
79_T128_V0.5130.98
4_D138_F0.5080.97
9_Q78_T0.5080.97
70_A74_Q0.5030.97
123_Q126_T0.5000.97
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1a3aA 2 0.979 100 0.164 Contact Map
2oq3A 1 0.993 100 0.164 Contact Map
2oqtA 2 0.986 100 0.169 Contact Map
3bjvA 2 0.986 100 0.17 Contact Map
3oxpA 2 0.993 100 0.178 Contact Map
1a6jA 4 0.979 100 0.182 Contact Map
4m62S 1 0.993 100 0.183 Contact Map
2a0jA 1 0.972 100 0.206 Contact Map
3urrA 2 0.979 100 0.209 Contact Map
3t43A 2 0.8951 100 0.224 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0067 seconds.