GREMLIN Database
YJHE - Putative uncharacterized protein YjhE
UniProt: P39355 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG12547
Length: 82 (70)
Sequences: 1868 (1250)
Seq/√Len: 149.3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
48_I57_L4.8501.00
60_Y64_A2.4611.00
43_I47_I2.2501.00
10_P14_V2.2471.00
67_V71_F2.2141.00
70_I73_T2.0861.00
27_S31_N2.0591.00
14_V18_I2.0211.00
45_F58_P1.9801.00
45_F49_I1.9121.00
49_I58_P1.8031.00
22_Y33_G1.7221.00
18_I26_A1.6911.00
66_L70_I1.5281.00
32_A37_A1.5261.00
15_P30_M1.4351.00
71_F74_F1.3521.00
50_D53_G1.3381.00
19_T22_Y1.3321.00
9_G13_A1.3021.00
11_I15_P1.2711.00
6_L68_I1.2021.00
23_V62_S1.1671.00
21_K25_I1.1661.00
8_I34_S1.1631.00
31_N38_D1.1601.00
65_L68_I1.1571.00
17_D23_V1.1391.00
48_I61_G1.1080.99
8_I12_R1.1070.99
18_I30_M1.0920.99
24_G46_G1.0750.99
53_G57_L1.0720.99
42_P49_I1.0470.99
56_S60_Y1.0430.99
47_I56_S1.0230.99
67_V70_I1.0180.99
38_D41_S1.0050.99
22_Y60_Y0.9960.99
6_L21_K0.9540.98
20_P36_V0.9470.98
28_G31_N0.9400.98
20_P26_A0.9370.98
24_G34_S0.9200.98
69_G72_L0.9170.98
31_N35_A0.9130.98
21_K70_I0.8980.97
8_I13_A0.8930.97
35_A38_D0.8710.97
17_D22_Y0.8600.97
47_I50_D0.8520.96
36_V40_I0.8430.96
72_L75_F0.8280.96
12_R28_G0.8280.96
49_I54_N0.8220.96
28_G34_S0.7890.95
9_G33_G0.7860.95
11_I14_V0.7830.94
12_R42_P0.7540.93
24_G67_V0.7510.93
26_A29_L0.7250.92
47_I53_G0.7070.91
11_I27_S0.7030.91
20_P30_M0.6970.90
21_K44_A0.6690.88
45_F57_L0.6640.88
37_A62_S0.6570.87
23_V27_S0.6540.87
10_P13_A0.6520.87
62_S66_L0.6460.86
61_G65_L0.6450.86
8_I60_Y0.6410.86
44_A61_G0.6350.86
39_I60_Y0.6290.85
8_I30_M0.6230.84
35_A41_S0.6180.84
17_D71_F0.6120.83
41_S59_F0.6070.83
23_V37_A0.6060.83
6_L45_F0.5980.82
16_M37_A0.5960.82
7_T35_A0.5910.81
31_N41_S0.5900.81
35_A42_P0.5850.81
44_A65_L0.5830.80
6_L9_G0.5750.79
55_W60_Y0.5720.79
50_D74_F0.5700.79
57_L61_G0.5690.79
52_T56_S0.5680.79
29_L58_P0.5650.78
51_K54_N0.5650.78
25_I29_L0.5650.78
52_T68_I0.5410.75
52_T65_L0.5390.75
19_T28_G0.5380.75
34_S64_A0.5370.75
18_I49_I0.5320.74
7_T56_S0.5310.74
22_Y37_A0.5270.73
48_I58_P0.5260.73
25_I64_A0.5170.72
7_T10_P0.5140.71
42_P56_S0.5090.71
54_N57_L0.5000.69
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1pw4A 1 0.9878 97.8 0.656 Contact Map
4oh3A 2 0.9878 97.6 0.668 Contact Map
4gc0A 1 1 97.6 0.67 Contact Map
3wdoA 1 0.9878 97.6 0.673 Contact Map
2gfpA 2 0.9878 97.5 0.675 Contact Map
4uvmA 1 0.9878 97.5 0.675 Contact Map
4q65A 1 0.9512 97.5 0.677 Contact Map
3o7qA 1 1 97.4 0.681 Contact Map
4zw9A 1 1 97.4 0.681 Contact Map
4ldsA 2 0.9878 97.4 0.685 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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