GREMLIN Database
YJGX - Putative phosphoethanolamine transferase YjgX
UniProt: P39349 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG12543
Length: 371 (318)
Sequences: 6040 (4767)
Seq/√Len: 267.3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
351_W365_P5.7941.00
119_W277_G4.8471.00
129_D337_S4.2261.00
224_A286_Y3.5201.00
131_Y340_I3.3281.00
119_W122_T3.2321.00
220_E282_I3.1831.00
99_G102_V2.9471.00
216_L236_M2.9171.00
281_G285_R2.8721.00
170_S228_S2.8521.00
280_D292_M2.7721.00
94_I164_A2.7061.00
95_V292_M2.6991.00
340_I366_L2.6441.00
218_E221_R2.5641.00
277_G281_G2.4211.00
92_D289_H2.3731.00
94_I353_T2.3711.00
115_P121_N2.2551.00
117_T121_N2.2191.00
108_S121_N2.2091.00
97_V294_Y2.1961.00
348_I367_T2.1891.00
108_S117_T2.1351.00
224_A282_I2.0941.00
291_A325_I2.0891.00
281_G284_R2.0411.00
251_P274_N2.0391.00
97_V276_L2.0201.00
93_T290_F2.0161.00
90_L289_H2.0161.00
110_Y127_F1.9481.00
96_I293_L1.8951.00
93_T230_K1.8811.00
282_I286_Y1.8731.00
217_Q278_Q1.8381.00
164_A353_T1.8231.00
221_R225_D1.7751.00
216_L220_E1.7651.00
234_L279_L1.7621.00
248_N271_K1.7431.00
327_A330_I1.7351.00
283_L292_M1.6751.00
253_N270_S1.6571.00
186_R191_A1.6521.00
282_I285_R1.6251.00
95_V230_K1.6161.00
213_K278_Q1.6041.00
172_W222_A1.5911.00
95_V290_F1.5761.00
215_L234_L1.5751.00
309_V312_Y1.5631.00
183_H186_R1.5391.00
102_V269_I1.5311.00
126_L334_Q1.5271.00
249_S252_N1.5161.00
219_T232_I1.5091.00
128_I323_L1.5061.00
96_I231_I1.5051.00
158_N166_K1.4991.00
275_F278_Q1.4961.00
293_L349_F1.4841.00
293_L325_I1.4751.00
316_Q320_S1.4751.00
311_H314_H1.4741.00
99_G272_L1.4691.00
254_Y270_S1.4461.00
163_L350_Q1.4411.00
213_K271_K1.4251.00
188_S191_A1.4151.00
102_V107_M1.4101.00
92_D291_A1.4061.00
240_H297_G1.3921.00
239_S269_I1.3861.00
212_D238_G1.3851.00
99_G294_Y1.3821.00
131_Y323_L1.3811.00
270_S274_N1.3751.00
104_R320_S1.3741.00
350_Q355_I1.3641.00
174_I232_I1.3631.00
148_Y151_E1.3611.00
94_I291_A1.3481.00
222_A225_D1.3471.00
117_T120_L1.3381.00
189_V192_S1.3361.00
236_M275_F1.3231.00
347_G363_F1.3151.00
216_L279_L1.3041.00
102_V294_Y1.3001.00
346_A361_P1.2961.00
129_D335_P1.2951.00
138_T235_H1.2941.00
138_T142_L1.2911.00
126_L336_V1.2881.00
220_E224_A1.2831.00
219_T234_L1.2701.00
102_V272_L1.2691.00
108_S115_P1.2611.00
195_E198_T1.2491.00
134_T144_R1.2321.00
327_A331_T1.2211.00
220_E286_Y1.2191.00
49_W53_M1.2171.00
310_H313_G1.2101.00
96_I295_F1.2091.00
49_W52_R1.2011.00
213_K275_F1.1971.00
174_I222_A1.1931.00
247_L252_N1.1901.00
278_Q281_G1.1761.00
173_W177_Q1.1741.00
127_F335_P1.1661.00
147_I159_N1.1661.00
119_W281_G1.1661.00
112_Y266_L1.1631.00
75_S78_G1.1621.00
183_H187_I1.1611.00
145_T295_F1.1571.00
91_Y167_A1.1571.00
310_H315_V1.1511.00
187_I191_A1.1481.00
118_P273_D1.1451.00
274_N278_Q1.1411.00
48_R51_L1.1281.00
48_R56_G1.1221.00
70_R73_Q1.1171.00
98_T295_F1.1101.00
345_F349_F1.1081.00
133_S321_V1.0921.00
173_W233_F1.0841.00
164_A350_Q1.0761.00
279_L292_M1.0711.00
93_T288_R1.0691.00
47_N50_P1.0681.00
106_Y266_L1.0661.00
47_N52_R1.0661.00
160_V231_I1.0651.00
280_D284_R1.0591.00
187_I192_S1.0521.00
328_S331_T1.0521.00
248_N251_P1.0511.00
212_D216_L1.0471.00
73_Q76_S1.0461.00
48_R52_R1.0461.00
48_R53_M1.0411.00
164_A231_I1.0411.00
311_H315_V1.0401.00
256_E260_R1.0371.00
46_V50_P1.0361.00
138_T143_S1.0341.00
149_D157_G1.0341.00
295_F342_A1.0291.00
291_A327_A1.0231.00
278_Q282_I1.0211.00
122_T284_R1.0201.00
50_P53_M1.0201.00
149_D152_Q1.0111.00
216_L275_F1.0111.00
148_Y347_G1.0041.00
239_S268_S1.0031.00
52_R56_G1.0031.00
138_T240_H0.9941.00
141_S342_A0.9921.00
106_Y269_I0.9911.00
173_W235_H0.9901.00
109_V127_F0.9791.00
310_H314_H0.9741.00
309_V313_G0.9741.00
119_W273_D0.9701.00
66_R70_R0.9701.00
167_A355_I0.9641.00
52_R55_K0.9601.00
323_L345_F0.9591.00
59_V63_D0.9551.00
67_E70_R0.9541.00
220_E278_Q0.9511.00
47_N56_G0.9411.00
223_L232_I0.9411.00
274_N277_G0.9381.00
66_R69_Q0.9371.00
95_V279_L0.9361.00
172_W232_I0.9341.00
47_N51_L0.9281.00
243_P300_L0.9251.00
188_S192_S0.9221.00
98_T142_L0.9081.00
145_T345_F0.9061.00
296_S321_V0.9061.00
184_D187_I0.9061.00
68_M72_E0.9041.00
130_D320_S0.9031.00
122_T277_G0.9031.00
212_D215_L0.9031.00
185_T188_S0.9031.00
254_Y267_A0.9031.00
195_E200_L0.8991.00
346_A350_Q0.8991.00
150_Y343_R0.8941.00
305_S308_P0.8921.00
172_W230_K0.8851.00
178_G181_G0.8831.00
55_K58_V0.8811.00
114_V266_L0.8811.00
291_A352_M0.8801.00
49_W55_K0.8731.00
250_X253_N0.8721.00
54_V58_V0.8711.00
102_V239_S0.8671.00
47_N54_V0.8641.00
163_L166_K0.8631.00
244_C264_C0.8581.00
65_L74_L0.8571.00
169_Y229_P0.8551.00
69_Q72_E0.8531.00
221_R224_A0.8491.00
247_L267_A0.8461.00
283_L287_S0.8421.00
212_D271_K0.8380.99
72_E76_S0.8330.99
312_Y315_V0.8320.99
276_L280_D0.8270.99
214_L217_Q0.8270.99
249_S253_N0.8270.99
97_V279_L0.8250.99
122_T281_G0.8230.99
94_I169_Y0.8210.99
101_S298_L0.8210.99
119_W274_N0.8210.99
96_I233_F0.8200.99
49_W56_G0.8170.99
284_R326_T0.8140.99
247_L251_P0.8140.99
46_V49_W0.8120.99
118_P121_N0.8090.99
46_V51_L0.8090.99
140_S143_S0.8070.99
72_E75_S0.8060.99
97_V292_M0.8060.99
316_Q319_Y0.7980.99
51_L55_K0.7970.99
130_D339_K0.7970.99
48_R57_T0.7970.99
218_E222_A0.7940.99
138_T145_T0.7890.99
47_N57_T0.7880.99
275_F279_L0.7840.99
73_Q79_L0.7840.99
252_N264_C0.7800.99
196_H200_L0.7750.99
50_P55_K0.7750.99
115_P270_S0.7740.99
295_F345_F0.7690.99
163_L346_A0.7680.99
251_P271_K0.7680.99
119_W280_D0.7650.99
174_I219_T0.7640.99
74_L78_G0.7630.99
87_X90_L0.7610.99
49_W57_T0.7610.99
56_G59_V0.7590.99
138_T297_G0.7590.99
100_E239_S0.7570.99
236_M272_L0.7560.99
98_T235_H0.7550.99
219_T223_L0.7520.99
168_G229_P0.7510.99
94_I231_I0.7510.99
247_L254_Y0.7460.99
223_L283_L0.7450.99
147_I150_Y0.7440.99
73_Q77_T0.7440.99
43_L46_V0.7440.99
95_V232_I0.7430.99
280_D326_T0.7390.99
186_R190_I0.7390.99
178_G184_D0.7380.99
50_P57_T0.7340.99
58_V62_T0.7340.99
180_L184_D0.7330.99
271_K275_F0.7330.99
276_L294_Y0.7320.99
288_R329_D0.7310.99
280_D294_Y0.7310.99
66_R73_Q0.7310.99
123_A277_G0.7310.99
132_T320_S0.7310.99
288_R328_S0.7300.99
42_V45_S0.7290.99
352_M367_T0.7280.99
69_Q75_S0.7260.99
186_R192_S0.7250.99
134_T341_S0.7250.99
291_A349_F0.7230.98
58_V61_T0.7200.98
238_G271_K0.7180.98
65_L71_Y0.7140.98
68_M71_Y0.7140.98
216_L278_Q0.7130.98
330_I333_H0.7100.98
178_G182_E0.7090.98
160_V349_F0.7070.98
252_N255_L0.7050.98
147_I151_E0.7050.98
70_R74_L0.7000.98
197_A200_L0.6970.98
74_L77_T0.6950.98
94_I349_F0.6920.98
98_T145_T0.6920.98
126_L331_T0.6900.98
93_T229_P0.6900.98
85_S367_T0.6860.98
116_T270_S0.6860.98
67_E74_L0.6860.98
51_L59_V0.6840.98
216_L272_L0.6830.98
51_L54_V0.6830.98
217_Q220_E0.6830.98
52_R59_V0.6810.98
209_K237_M0.6770.98
77_T80_T0.6740.98
123_A284_R0.6730.98
92_D229_P0.6720.98
65_L68_M0.6690.98
211_D215_L0.6670.97
47_N55_K0.6650.97
116_T120_L0.6610.97
98_T233_F0.6610.97
55_K59_V0.6600.97
185_T189_V0.6590.97
96_I145_T0.6570.97
172_W175_S0.6570.97
238_G268_S0.6530.97
148_Y152_Q0.6530.97
169_Y353_T0.6480.97
321_V342_A0.6460.97
210_T271_K0.6450.97
214_L218_E0.6450.97
53_M56_G0.6440.97
309_V315_V0.6410.97
103_R302_V0.6400.97
45_S55_K0.6400.97
265_Y269_I0.6390.97
95_V283_L0.6390.97
67_E71_Y0.6380.97
43_L47_N0.6350.97
132_T319_Y0.6340.97
96_I345_F0.6320.96
105_D317_G0.6310.96
75_S79_L0.6300.96
263_A267_A0.6300.96
196_H199_F0.6300.96
138_T144_R0.6290.96
76_S79_L0.6260.96
164_A355_I0.6260.96
99_G276_L0.6260.96
305_S317_G0.6240.96
65_L72_E0.6230.96
64_T68_M0.6220.96
217_Q282_I0.6220.96
91_Y229_P0.6220.96
48_R55_K0.6190.96
222_A230_K0.6190.96
103_R299_G0.6180.96
123_A280_D0.6150.96
294_Y324_I0.6140.96
57_T62_T0.6120.96
53_M58_V0.6090.96
70_R76_S0.6060.96
45_S49_W0.6050.96
300_L318_G0.6040.95
66_R71_Y0.6010.95
197_A201_K0.6000.95
272_L275_F0.6000.95
46_V55_K0.6000.95
252_N267_A0.5990.95
52_R62_T0.5990.95
100_E240_H0.5990.95
344_H363_F0.5950.95
102_V120_L0.5940.95
178_G195_E0.5920.95
323_L340_I0.5920.95
46_V53_M0.5910.95
50_P56_G0.5890.95
73_Q78_G0.5870.95
322_P325_I0.5860.95
116_T266_L0.5850.95
60_G63_D0.5850.95
51_L58_V0.5840.95
271_K274_N0.5820.94
45_S52_R0.5810.94
100_E297_G0.5810.94
46_V52_R0.5800.94
173_W187_I0.5800.94
212_D236_M0.5780.94
301_S318_G0.5780.94
64_T71_Y0.5770.94
309_V314_H0.5760.94
185_T191_A0.5760.94
120_L276_L0.5750.94
45_S48_R0.5740.94
51_L56_G0.5730.94
83_K86_R0.5710.94
331_T334_Q0.5690.94
45_S53_M0.5680.94
52_R60_G0.5670.94
223_L279_L0.5650.94
147_I152_Q0.5620.93
253_N256_E0.5610.93
109_V121_N0.5600.93
161_V171_T0.5600.93
317_G320_S0.5590.93
165_A171_T0.5580.93
193_D199_F0.5560.93
230_K290_F0.5540.93
53_M57_T0.5540.93
138_T298_L0.5540.93
43_L58_V0.5530.93
45_S58_V0.5520.93
239_S272_L0.5510.93
267_A270_S0.5480.93
93_T289_H0.5460.92
94_I293_L0.5450.92
279_L282_I0.5440.92
61_T65_L0.5420.92
347_G361_P0.5420.92
193_D198_T0.5410.92
106_Y265_Y0.5410.92
43_L48_R0.5380.92
64_T67_E0.5360.92
71_Y77_T0.5350.92
104_R110_Y0.5330.92
137_S140_S0.5320.91
70_R79_L0.5320.91
344_H348_I0.5310.91
254_Y263_A0.5300.91
70_R77_T0.5300.91
45_S50_P0.5300.91
115_P118_P0.5300.91
49_W58_V0.5300.91
122_T125_G0.5300.91
69_Q73_Q0.5290.91
108_S116_T0.5270.91
184_D188_S0.5240.91
144_R343_R0.5240.91
140_S144_R0.5230.91
177_Q235_H0.5230.91
101_S300_L0.5220.91
122_T280_D0.5210.91
52_R57_T0.5190.90
56_G61_T0.5180.90
217_Q221_R0.5180.90
66_R78_G0.5150.90
103_R304_D0.5150.90
160_V346_A0.5150.90
99_G239_S0.5140.90
59_V62_T0.5140.90
53_M63_D0.5130.90
46_V60_G0.5130.90
163_L355_I0.5120.90
88_A91_Y0.5110.90
120_L324_I0.5110.90
99_G216_L0.5100.90
54_V61_T0.5100.90
47_N53_M0.5100.90
183_H190_I0.5080.89
46_V54_V0.5080.89
362_P365_P0.5070.89
102_V117_T0.5060.89
133_S141_S0.5050.89
54_V57_T0.5040.89
92_D327_A0.5040.89
48_R59_V0.5040.89
165_A191_A0.5010.89
42_V65_L0.5010.89
209_K214_L0.5000.89
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4uorA 3 0.8113 100 0.387 Contact Map
2w5qA 1 0.8221 100 0.389 Contact Map
4kavA 1 0.8032 100 0.395 Contact Map
3lxqA 1 0.8113 100 0.401 Contact Map
2w8dA 1 0.8248 100 0.403 Contact Map
4upkA 3 0.7493 100 0.404 Contact Map
4uopA 2 0.8194 100 0.405 Contact Map
4tn0A 1 0.7547 100 0.408 Contact Map
2vqrA 3 0.7466 100 0.411 Contact Map
4uplA 2 0.7547 100 0.411 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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