IDNT - ECOLI - GREMLIN Contacts

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IDNT - Gnt-II system L-idonate transporter

UniProt:	P39344	Sequences: MPLIIIAAGVALLLILMIGFKVNGFIALVLVAAVVGFAEGMDAQAVLHSIQNGIGSTLGGLAMILGFGAMLGKLISDTGAAQRIATTLIATFGKKRVQWALVITGLVVGLAMFFEVGFVLLLPLVFTIVASSGLPLLYVGVPMVAALSVTHCFLPPHPGPTAIATIFEANLGTTLLYGFIITIPTVIVAGPLFSKLLTRFEKAPPEGLFNPHLFSEEEMPSFWNSIFAAVIPVILMAIAAVCEITLPKTNTVRLFFEFVGNPAVALFIAIVIAIFTLGRRNGRTIEQIMDIIGDSIGAIAMIVFIIAGGGAFKQVLVDSGVGHYISHLMTGTTLSPLLMCWTVAALLRIALGSATVAAITTAGVVLPIINVTHADPALMVLATGAGSVIASHVNDPGFWLFKGYFNLTVGETLRTWTVMETLISIMGLLGVLAINAVLH	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG12539
Length:	439 (417)
Sequences:	5618 (3775)
Seq/√Len:	184.9

ECOLI - IDNT YJHF GNTP GNTU GNTT YGBN DSDX YFCC DCUC DCUD
BACSU - YOJA GNTP YXJC YCGA
HALSA - Q9HNF6 Q9HNR2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
294_D	297_G	3.783	1.00
262_P	266_L	3.462	1.00
332_T	335_S	3.267	1.00
9_G	312_F	3.062	1.00
12_L	34_V	3.022	1.00
180_I	184_P	3.020	1.00
228_A	232_P	2.886	1.00
314_Q	318_D	2.879	1.00
77_D	291_I	2.849	1.00
87_T	91_T	2.843	1.00
408_T	411_E	2.818	1.00
284_T	287_Q	2.801	1.00
323_H	327_H	2.747	1.00
9_G	35_V	2.713	1.00
196_L	200_F	2.665	1.00
222_F	226_I	2.656	1.00
338_L	428_L	2.641	1.00
262_P	265_A	2.629	1.00
231_I	272_I	2.569	1.00
87_T	222_F	2.488	1.00
232_P	236_M	2.482	1.00
421_T	425_I	2.430	1.00
49_S	318_D	2.350	1.00
221_S	224_N	2.318	1.00
77_D	287_Q	2.313	1.00
11_A	15_I	2.310	1.00
182_T	185_T	2.276	1.00
15_I	19_G	2.250	1.00
341_W	424_S	2.250	1.00
87_T	90_A	2.218	1.00
327_H	330_T	2.208	1.00
183_I	187_I	2.190	1.00
223_W	227_F	2.186	1.00
429_L	433_A	2.177	1.00
425_I	429_L	2.153	1.00
48_H	52_N	2.127	1.00
225_S	228_A	2.076	1.00
188_V	426_M	2.024	1.00
344_A	361_T	1.998	1.00
197_L	200_F	1.967	1.00
82_Q	86_T	1.945	1.00
261_N	266_L	1.938	1.00
229_A	236_M	1.910	1.00
193_F	197_L	1.908	1.00
52_N	56_S	1.899	1.00
190_G	193_F	1.882	1.00
197_L	201_E	1.819	1.00
45_A	48_H	1.786	1.00
201_E	205_P	1.778	1.00
266_L	269_A	1.771	1.00
167_F	383_T	1.763	1.00
200_F	204_P	1.745	1.00
42_D	45_A	1.741	1.00
232_P	240_A	1.737	1.00
266_L	270_I	1.693	1.00
176_L	180_I	1.679	1.00
193_F	196_L	1.676	1.00
204_P	207_G	1.664	1.00
414_R	418_V	1.648	1.00
340_C	383_T	1.646	1.00
73_K	77_D	1.646	1.00
345_A	389_I	1.644	1.00
235_L	239_A	1.642	1.00
42_D	46_V	1.633	1.00
256_F	260_G	1.632	1.00
369_I	379_M	1.621	1.00
190_G	194_S	1.620	1.00
161_T	164_A	1.615	1.00
324_Y	328_L	1.598	1.00
12_L	31_V	1.589	1.00
228_A	236_M	1.585	1.00
163_I	358_A	1.584	1.00
174_T	380_V	1.563	1.00
257_E	260_G	1.555	1.00
349_I	390_A	1.548	1.00
175_L	178_G	1.542	1.00
105_G	108_V	1.536	1.00
396_P	401_F	1.531	1.00
193_F	200_F	1.531	1.00
199_R	203_A	1.522	1.00
12_L	16_L	1.522	1.00
224_N	228_A	1.521	1.00
191_P	194_S	1.518	1.00
198_T	201_E	1.518	1.00
192_L	195_K	1.515	1.00
113_F	116_V	1.510	1.00
235_L	268_I	1.510	1.00
110_L	113_F	1.504	1.00
225_S	232_P	1.502	1.00
373_H	376_P	1.499	1.00
140_G	405_F	1.485	1.00
193_F	201_E	1.478	1.00
101_L	104_T	1.467	1.00
152_C	388_V	1.466	1.00
170_N	173_T	1.460	1.00
83_R	87_T	1.459	1.00
396_P	400_L	1.451	1.00
264_V	269_A	1.450	1.00
418_V	422_L	1.439	1.00
236_M	240_A	1.434	1.00
182_T	186_V	1.431	1.00
397_G	401_F	1.422	1.00
54_I	62_A	1.421	1.00
94_K	131_S	1.421	1.00
197_L	204_P	1.420	1.00
5_I	38_A	1.417	1.00
171_L	176_L	1.417	1.00
99_W	191_P	1.412	1.00
22_V	27_A	1.400	1.00
13_L	31_V	1.387	1.00
224_N	227_F	1.383	1.00
261_N	265_A	1.381	1.00
220_P	225_S	1.379	1.00
262_P	267_F	1.369	1.00
201_E	204_P	1.367	1.00
389_I	424_S	1.366	1.00
239_A	243_E	1.363	1.00
176_L	179_F	1.360	1.00
177_Y	180_I	1.360	1.00
114_F	117_G	1.359	1.00
116_V	119_V	1.354	1.00
275_F	280_R	1.346	1.00
290_D	294_D	1.338	1.00
260_G	265_A	1.336	1.00
180_I	185_T	1.336	1.00
69_A	292_I	1.333	1.00
115_E	396_P	1.328	1.00
44_Q	48_H	1.311	1.00
265_A	269_A	1.308	1.00
53_G	314_Q	1.307	1.00
200_F	203_A	1.301	1.00
191_P	195_K	1.287	1.00
261_N	264_V	1.280	1.00
287_Q	290_D	1.273	1.00
313_K	317_V	1.273	1.00
166_I	362_A	1.272	1.00
432_L	435_N	1.271	1.00
229_A	232_P	1.267	1.00
396_P	399_W	1.259	1.00
223_W	228_A	1.256	1.00
103_I	107_V	1.251	1.00
237_A	240_A	1.250	1.00
221_S	225_S	1.249	1.00
50_I	311_A	1.243	1.00
263_A	267_F	1.226	1.00
49_S	314_Q	1.217	1.00
178_G	181_I	1.216	1.00
419_M	423_I	1.209	1.00
45_A	49_S	1.208	1.00
228_A	244_I	1.193	1.00
179_F	183_I	1.182	1.00
202_K	205_P	1.178	1.00
78_T	277_L	1.175	1.00
192_L	196_L	1.171	1.00
133_G	204_P	1.171	1.00
286_E	290_D	1.164	1.00
171_L	175_L	1.164	1.00
73_K	291_I	1.163	1.00
77_D	294_D	1.162	1.00
222_F	225_S	1.156	1.00
204_P	208_L	1.153	1.00
57_T	310_G	1.153	1.00
410_G	414_R	1.151	1.00
224_N	232_P	1.151	1.00
115_E	306_I	1.147	1.00
27_A	31_V	1.140	1.00
130_A	136_L	1.138	1.00
34_V	38_A	1.133	1.00
184_P	188_V	1.133	1.00
181_I	184_P	1.133	1.00
31_V	34_V	1.131	1.00
370_N	376_P	1.128	1.00
385_A	431_V	1.123	1.00
269_A	273_A	1.121	1.00
81_A	85_A	1.119	1.00
430_G	434_I	1.119	1.00
222_F	229_A	1.115	1.00
201_E	208_L	1.115	1.00
237_A	241_V	1.112	1.00
177_Y	381_L	1.111	1.00
398_F	402_K	1.105	1.00
274_I	278_G	1.104	1.00
177_Y	181_I	1.102	1.00
102_V	105_G	1.101	1.00
103_I	106_L	1.099	1.00
227_F	231_I	1.097	1.00
353_S	356_V	1.095	1.00
181_I	434_I	1.089	1.00
175_L	180_I	1.089	1.00
240_A	244_I	1.088	1.00
341_W	428_L	1.084	1.00
228_A	231_I	1.082	1.00
278_G	281_N	1.082	1.00
197_L	203_A	1.079	1.00
409_V	413_L	1.076	1.00
389_I	421_T	1.073	1.00
101_L	105_G	1.071	1.00
177_Y	377_A	1.070	1.00
205_P	208_L	1.068	1.00
306_I	396_P	1.061	1.00
86_T	131_S	1.061	1.00
349_I	389_I	1.058	1.00
338_L	432_L	1.050	1.00
223_W	226_I	1.045	1.00
366_L	370_N	1.041	1.00
71_L	269_A	1.037	1.00
187_I	192_L	1.037	1.00
101_L	107_V	1.032	1.00
216_E	220_P	1.027	1.00
145_A	190_G	1.025	1.00
188_V	192_L	1.021	1.00
48_H	51_Q	1.019	1.00
190_G	195_K	1.012	0.99
104_T	107_V	1.011	0.99
71_L	270_I	1.010	0.99
427_G	431_V	1.009	0.99
196_L	204_P	1.008	0.99
118_F	404_Y	1.003	0.99
82_Q	217_E	1.002	0.99
232_P	237_A	1.001	0.99
6_I	10_V	0.998	0.99
104_T	108_V	0.997	0.99
426_M	430_G	0.994	0.99
240_A	243_E	0.993	0.99
173_T	176_L	0.992	0.99
272_I	276_T	0.991	0.99
277_L	280_R	0.991	0.99
175_L	179_F	0.984	0.99
264_V	267_F	0.983	0.99
194_S	198_T	0.982	0.99
84_I	225_S	0.982	0.99
391_S	395_D	0.981	0.99
265_A	270_I	0.977	0.99
239_A	244_I	0.975	0.99
262_P	269_A	0.973	0.99
385_A	427_G	0.972	0.99
86_T	90_A	0.970	0.99
263_A	266_L	0.967	0.99
194_S	197_L	0.959	0.99
150_T	157_H	0.957	0.99
196_L	199_R	0.955	0.99
174_T	377_A	0.952	0.99
261_N	269_A	0.942	0.99
264_V	268_I	0.942	0.99
114_F	397_G	0.942	0.99
402_K	412_T	0.940	0.99
261_N	270_I	0.938	0.99
80_A	225_S	0.937	0.99
74_L	273_A	0.937	0.99
225_S	244_I	0.937	0.99
271_V	275_F	0.936	0.99
91_T	95_K	0.935	0.99
354_A	391_S	0.934	0.99
273_A	277_L	0.934	0.99
218_E	221_S	0.933	0.99
200_F	208_L	0.930	0.99
417_T	421_T	0.929	0.99
115_E	118_F	0.928	0.99
101_L	108_V	0.927	0.99
225_S	229_A	0.924	0.99
241_V	244_I	0.923	0.99
397_G	402_K	0.920	0.99
160_P	164_A	0.919	0.99
320_G	323_H	0.916	0.99
9_G	34_V	0.916	0.99
299_I	303_V	0.915	0.99
241_V	245_T	0.914	0.99
16_L	27_A	0.912	0.99
169_A	172_G	0.912	0.99
181_I	185_T	0.912	0.99
39_E	42_D	0.903	0.99
432_L	436_A	0.902	0.99
150_T	154_L	0.894	0.99
197_L	422_L	0.888	0.99
195_K	198_T	0.887	0.99
63_M	67_F	0.885	0.99
420_E	423_I	0.880	0.99
314_Q	317_V	0.878	0.99
274_I	292_I	0.878	0.99
16_L	22_V	0.875	0.99
378_L	434_I	0.873	0.98
178_G	184_P	0.872	0.98
390_A	417_T	0.870	0.98
229_A	240_A	0.869	0.98
200_F	205_P	0.867	0.98
411_E	414_R	0.861	0.98
137_L	203_A	0.861	0.98
174_T	177_Y	0.860	0.98
391_S	416_W	0.857	0.98
226_I	230_V	0.854	0.98
332_T	337_L	0.849	0.98
275_F	279_R	0.849	0.98
243_E	257_E	0.846	0.98
270_I	274_I	0.844	0.98
184_P	187_I	0.843	0.98
348_R	395_D	0.839	0.98
39_E	319_S	0.837	0.98
25_F	304_F	0.833	0.98
115_E	119_V	0.829	0.98
148_S	420_E	0.823	0.98
169_A	174_T	0.820	0.98
109_G	113_F	0.818	0.98
35_V	312_F	0.817	0.98
99_W	103_I	0.816	0.98
64_I	306_I	0.815	0.98
381_L	431_V	0.815	0.98
273_A	276_T	0.814	0.98
100_A	108_V	0.813	0.98
193_F	198_T	0.811	0.98
112_M	119_V	0.811	0.98
277_L	288_I	0.809	0.98
233_V	237_A	0.809	0.98
141_V	145_A	0.807	0.97
222_F	232_P	0.807	0.97
228_A	276_T	0.807	0.97
86_T	219_M	0.803	0.97
102_V	186_V	0.802	0.97
162_A	166_I	0.801	0.97
224_N	236_M	0.798	0.97
216_E	219_M	0.796	0.97
227_F	276_T	0.796	0.97
397_G	400_L	0.794	0.97
198_T	205_P	0.794	0.97
232_P	235_L	0.792	0.97
378_L	431_V	0.792	0.97
134_L	138_Y	0.789	0.97
224_N	280_R	0.788	0.97
256_F	259_V	0.787	0.97
197_L	205_P	0.784	0.97
7_A	11_A	0.784	0.97
367_P	372_T	0.781	0.97
366_L	369_I	0.780	0.97
348_R	354_A	0.780	0.97
377_A	381_L	0.779	0.97
178_G	185_T	0.778	0.97
223_W	232_P	0.778	0.97
117_G	147_L	0.777	0.97
41_M	49_S	0.776	0.97
12_L	15_I	0.775	0.97
402_K	405_F	0.774	0.97
173_T	377_A	0.774	0.97
416_W	420_E	0.774	0.97
203_A	207_G	0.773	0.97
344_A	357_A	0.773	0.97
185_T	430_G	0.772	0.97
93_G	100_A	0.769	0.97
109_G	114_F	0.766	0.97
382_A	386_G	0.766	0.97
351_L	360_T	0.764	0.97
239_A	242_C	0.763	0.96
287_Q	291_I	0.763	0.96
214_F	217_E	0.762	0.96
52_N	55_G	0.762	0.96
381_L	385_A	0.762	0.96
357_A	395_D	0.760	0.96
357_A	361_T	0.757	0.96
192_L	200_F	0.757	0.96
222_F	227_F	0.756	0.96
198_T	202_K	0.752	0.96
188_V	422_L	0.751	0.96
181_I	430_G	0.749	0.96
398_F	401_F	0.748	0.96
68_G	295_S	0.746	0.96
201_E	206_E	0.742	0.96
231_I	234_I	0.741	0.96
223_W	245_T	0.741	0.96
197_L	207_G	0.739	0.96
200_F	207_G	0.738	0.96
174_T	178_G	0.735	0.96
83_R	225_S	0.734	0.96
8_A	12_L	0.734	0.96
235_L	242_C	0.732	0.96
196_L	207_G	0.731	0.96
199_R	202_K	0.730	0.95
354_A	396_P	0.729	0.95
73_K	294_D	0.728	0.95
222_F	236_M	0.725	0.95
214_F	218_E	0.725	0.95
345_A	424_S	0.724	0.95
114_F	118_F	0.723	0.95
340_C	365_V	0.721	0.95
5_I	31_V	0.720	0.95
30_L	34_V	0.719	0.95
129_V	139_V	0.718	0.95
399_W	402_K	0.717	0.95
190_G	197_L	0.717	0.95
274_I	277_L	0.714	0.95
109_G	117_G	0.714	0.95
236_M	239_A	0.713	0.95
375_D	378_L	0.713	0.95
133_G	202_K	0.713	0.95
266_L	273_A	0.710	0.95
329_M	343_V	0.710	0.95
222_F	230_V	0.710	0.95
181_I	381_L	0.710	0.95
234_I	238_I	0.707	0.95
166_I	363_G	0.704	0.95
109_G	112_M	0.703	0.94
100_A	107_V	0.702	0.94
220_P	224_N	0.702	0.94
332_T	336_P	0.699	0.94
226_I	232_P	0.699	0.94
73_K	76_S	0.698	0.94
116_V	159_G	0.698	0.94
185_T	188_V	0.697	0.94
113_F	117_G	0.697	0.94
52_N	318_D	0.696	0.94
240_A	245_T	0.696	0.94
196_L	201_E	0.696	0.94
33_A	264_V	0.694	0.94
428_L	432_L	0.693	0.94
35_V	315_V	0.692	0.94
146_A	150_T	0.692	0.94
94_K	132_S	0.691	0.94
112_M	116_V	0.691	0.94
412_T	416_W	0.691	0.94
23_N	26_I	0.690	0.94
220_P	228_A	0.690	0.94
345_A	390_A	0.689	0.94
203_A	206_E	0.687	0.94
417_T	424_S	0.687	0.94
194_S	200_F	0.684	0.94
238_I	244_I	0.683	0.94
378_L	435_N	0.681	0.93
193_F	418_V	0.680	0.93
52_N	314_Q	0.678	0.93
135_P	201_E	0.678	0.93
260_G	273_A	0.677	0.93
5_I	39_E	0.676	0.93
404_Y	407_L	0.672	0.93
238_I	243_E	0.672	0.93
172_G	176_L	0.671	0.93
203_A	411_E	0.671	0.93
348_R	387_S	0.668	0.93
175_L	182_T	0.668	0.93
242_C	245_T	0.668	0.93
113_F	119_V	0.667	0.93
333_T	337_L	0.667	0.93
213_L	216_E	0.666	0.93
220_P	232_P	0.666	0.93
12_L	19_G	0.666	0.93
269_A	272_I	0.665	0.93
275_F	278_G	0.665	0.93
358_A	387_S	0.664	0.93
222_F	228_A	0.663	0.93
5_I	9_G	0.662	0.93
148_S	388_V	0.662	0.93
197_L	208_L	0.659	0.92
215_S	219_M	0.658	0.92
372_T	376_P	0.657	0.92
129_V	134_L	0.656	0.92
415_T	418_V	0.654	0.92
16_L	30_L	0.654	0.92
228_A	235_L	0.653	0.92
348_R	391_S	0.653	0.92
231_I	235_L	0.651	0.92
178_G	186_V	0.651	0.92
327_H	331_G	0.650	0.92
367_P	371_V	0.650	0.92
178_G	182_T	0.649	0.92
236_M	244_I	0.648	0.92
41_M	46_V	0.648	0.92
162_A	359_I	0.647	0.92
190_G	196_L	0.644	0.91
190_G	200_F	0.643	0.91
153_F	427_G	0.640	0.91
400_L	407_L	0.638	0.91
96_R	99_W	0.636	0.91
140_G	407_L	0.635	0.91
63_M	66_G	0.634	0.91
228_A	240_A	0.634	0.91
324_Y	327_H	0.631	0.91
226_I	229_A	0.631	0.91
354_A	387_S	0.630	0.91
238_I	242_C	0.629	0.90
196_L	205_P	0.629	0.90
349_I	417_T	0.627	0.90
172_G	175_L	0.623	0.90
276_T	280_R	0.623	0.90
151_H	155_P	0.620	0.90
13_L	350_A	0.620	0.90
348_R	357_A	0.619	0.90
171_L	178_G	0.617	0.90
344_A	387_S	0.617	0.90
236_M	242_C	0.617	0.90
265_A	273_A	0.617	0.90
193_F	422_L	0.616	0.90
99_W	106_L	0.615	0.89
80_A	83_R	0.614	0.89
233_V	236_M	0.613	0.89
180_I	186_V	0.612	0.89
225_S	236_M	0.612	0.89
162_A	167_F	0.611	0.89
410_G	413_L	0.611	0.89
117_G	157_H	0.610	0.89
153_F	385_A	0.610	0.89
10_V	13_L	0.610	0.89
403_G	407_L	0.609	0.89
90_A	199_R	0.607	0.89
266_L	274_I	0.607	0.89
195_K	199_R	0.606	0.89
264_V	270_I	0.603	0.89
125_V	129_V	0.602	0.88
26_I	270_I	0.600	0.88
125_V	143_M	0.600	0.88
391_S	420_E	0.598	0.88
215_S	331_G	0.597	0.88
358_A	361_T	0.597	0.88
401_F	407_L	0.595	0.88
184_P	430_G	0.595	0.88
47_L	51_Q	0.594	0.88
392_H	420_E	0.591	0.88
223_W	237_A	0.591	0.88
322_G	326_S	0.591	0.88
183_I	186_V	0.591	0.88
9_G	39_E	0.590	0.87
262_P	268_I	0.589	0.87
91_T	94_K	0.589	0.87
193_F	203_A	0.587	0.87
351_L	356_V	0.586	0.87
221_S	228_A	0.585	0.87
102_V	106_L	0.585	0.87
407_L	411_E	0.584	0.87
269_A	279_R	0.583	0.87
35_V	38_A	0.583	0.87
83_R	222_F	0.582	0.87
210_N	215_S	0.580	0.87
68_G	85_A	0.580	0.87
265_A	268_I	0.577	0.86
110_L	115_E	0.576	0.86
111_A	114_F	0.576	0.86
393_V	413_L	0.576	0.86
403_G	406_N	0.575	0.86
36_G	46_V	0.573	0.86
305_I	359_I	0.572	0.86
380_V	423_I	0.572	0.86
164_A	171_L	0.571	0.86
226_I	236_M	0.571	0.86
145_A	419_M	0.570	0.86
32_A	36_G	0.567	0.85
171_L	179_F	0.566	0.85
239_A	245_T	0.566	0.85
95_K	208_L	0.565	0.85
174_T	180_I	0.565	0.85
102_V	108_V	0.563	0.85
232_P	245_T	0.563	0.85
106_L	110_L	0.562	0.85
102_V	107_V	0.562	0.85
218_E	287_Q	0.562	0.85
222_F	244_I	0.562	0.85
258_F	261_N	0.562	0.85
122_L	405_F	0.561	0.85
219_M	223_W	0.559	0.85
335_S	338_L	0.556	0.84
347_L	351_L	0.555	0.84
398_F	404_Y	0.555	0.84
5_I	321_V	0.555	0.84
238_I	245_T	0.554	0.84
211_P	214_F	0.552	0.84
267_F	270_I	0.552	0.84
96_R	102_V	0.551	0.84
111_A	116_V	0.550	0.84
210_N	214_F	0.549	0.84
5_I	34_V	0.548	0.83
100_A	106_L	0.546	0.83
144_V	399_W	0.546	0.83
400_L	405_F	0.545	0.83
231_I	236_M	0.544	0.83
33_A	211_P	0.543	0.83
29_V	67_F	0.543	0.83
229_A	237_A	0.542	0.83
58_L	307_A	0.541	0.83
149_V	152_C	0.541	0.83
149_V	182_T	0.540	0.83
176_L	184_P	0.538	0.82
112_M	117_G	0.538	0.82
230_V	233_V	0.536	0.82
211_P	215_S	0.533	0.82
361_T	383_T	0.532	0.82
426_M	429_L	0.531	0.81
25_F	29_V	0.531	0.81
173_T	179_F	0.531	0.81
113_F	159_G	0.530	0.81
433_A	436_A	0.530	0.81
32_A	311_A	0.529	0.81
223_W	234_I	0.527	0.81
37_F	43_A	0.527	0.81
83_R	219_M	0.526	0.81
143_M	146_A	0.526	0.81
265_A	276_T	0.526	0.81
423_I	427_G	0.524	0.81
195_K	203_A	0.523	0.80
141_V	415_T	0.523	0.80
274_I	288_I	0.523	0.80
220_P	240_A	0.522	0.80
171_L	180_I	0.522	0.80
97_V	104_T	0.522	0.80
218_E	222_F	0.521	0.80
345_A	349_I	0.521	0.80
326_S	329_M	0.521	0.80
308_G	312_F	0.519	0.80
98_Q	101_L	0.519	0.80
220_P	244_I	0.518	0.80
109_G	150_T	0.517	0.80
230_V	237_A	0.515	0.79
198_T	204_P	0.513	0.79
149_V	420_E	0.513	0.79
315_V	318_D	0.513	0.79
301_M	305_I	0.513	0.79
272_I	275_F	0.512	0.79
400_L	403_G	0.510	0.79
152_C	354_A	0.510	0.79
195_K	200_F	0.509	0.79
185_T	426_M	0.509	0.79
88_L	92_F	0.509	0.79
221_S	232_P	0.508	0.79
105_G	121_L	0.507	0.78
269_A	277_L	0.506	0.78
83_R	221_S	0.506	0.78
232_P	239_A	0.505	0.78
212_H	215_S	0.505	0.78
354_A	388_V	0.504	0.78
227_F	234_I	0.503	0.78
232_P	243_E	0.501	0.78
200_F	206_E	0.500	0.77
356_V	360_T	0.500	0.77

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4r1iA	2	0.9772	100	0.55	Contact Map
4r0cA	3	0.9727	100	0.564	Contact Map
4f35D	2	0.8975	100	0.602	Contact Map
4pd6A	3	0.7654	90.8	0.931	Contact Map
4dx5A	3	0.3599	59.3	0.949	Contact Map
2cfqA	1	0.8178	54.9	0.951	Contact Map
3aqpA	1	0.3713	42.9	0.954	Contact Map
3qe7A	2	0.4465	34.1	0.956	Contact Map
2a65A	2	0.615	29.8	0.958	Contact Map
3giaA	1	0.4465	27.5	0.959	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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