GREMLIN Database
YJGH - RutC family protein YjgH
UniProt: P39332 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG12527
Length: 131 (114)
Sequences: 7649 (4895)
Seq/√Len: 458.5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
54_R97_E3.1261.00
61_H71_F2.9661.00
76_D123_K2.6691.00
69_C73_D2.6101.00
48_D51_Q2.5511.00
50_Q90_D2.3861.00
54_R58_D2.1241.00
80_F110_V2.0591.00
50_Q93_T1.9691.00
79_S91_I1.9561.00
60_L124_V1.9511.00
37_V118_F1.9281.00
58_D98_I1.9181.00
52_Q119_D1.8531.00
111_G114_W1.8321.00
69_C128_I1.8071.00
61_H65_A1.7671.00
64_L126_A1.7071.00
86_N119_D1.7011.00
55_L59_N1.6111.00
31_L69_C1.6101.00
54_R98_I1.5811.00
84_P111_G1.5501.00
77_V124_V1.5261.00
27_S75_I1.5231.00
114_W117_G1.5181.00
45_P118_F1.5051.00
27_S127_R1.5041.00
58_D61_H1.4391.00
26_R29_D1.4251.00
26_R128_I1.4171.00
32_F125_I1.4021.00
70_T73_D1.3721.00
74_I124_V1.3641.00
49_F53_V1.3491.00
55_L58_D1.3381.00
38_G118_F1.3311.00
81_H109_A1.3051.00
90_D93_T1.2911.00
46_E51_Q1.2581.00
81_H91_I1.2511.00
35_G121_E1.2341.00
108_T123_K1.2181.00
78_T123_K1.2171.00
94_V97_E1.1781.00
82_T86_N1.1641.00
54_R94_V1.1631.00
31_L67_A1.1581.00
40_R44_T1.1391.00
92_M107_W1.1301.00
26_R31_L1.1191.00
95_K107_W1.0801.00
64_L69_C1.0641.00
24_A63_T1.0571.00
33_V63_T1.0511.00
30_L127_R1.0491.00
80_F112_V1.0281.00
100_S104_Y1.0241.00
61_H98_I1.0151.00
33_V124_V1.0081.00
82_T114_W0.9961.00
30_L75_I0.9931.00
74_I99_F0.9881.00
38_G56_A0.9741.00
80_F108_T0.9681.00
50_Q94_V0.9621.00
65_A70_T0.9561.00
100_S103_P0.9471.00
85_E114_W0.9341.00
77_V95_K0.9281.00
13_H65_A0.9281.00
83_D86_N0.9201.00
82_T119_D0.9161.00
49_F91_I0.9121.00
53_V91_I0.9091.00
26_R69_C0.9041.00
71_F74_I0.9041.00
50_Q54_R0.9021.00
64_L74_I0.8881.00
62_A65_A0.8831.00
93_T96_N0.8711.00
93_T97_E0.8701.00
29_D127_R0.8641.00
14_S23_A0.8561.00
39_S43_G0.8421.00
86_N90_D0.8241.00
88_F109_A0.8151.00
57_F98_I0.8111.00
82_T117_G0.8091.00
36_Q63_T0.8091.00
71_F98_I0.8011.00
77_V99_F0.7991.00
79_S107_W0.7901.00
31_L128_I0.7771.00
38_G52_Q0.7661.00
47_P52_Q0.7631.00
31_L126_A0.7511.00
20_R92_M0.7411.00
96_N104_Y0.7401.00
57_F71_F0.7381.00
57_F122_I0.7371.00
50_Q97_E0.7351.00
78_T125_I0.7211.00
89_E93_T0.7161.00
82_T112_V0.7101.00
51_Q54_R0.7081.00
94_V98_I0.6911.00
46_E52_Q0.6911.00
81_H84_P0.6901.00
72_D100_S0.6891.00
82_T113_T0.6811.00
53_V120_F0.6791.00
74_I126_A0.6751.00
47_P51_Q0.6731.00
24_A67_A0.6621.00
86_N111_G0.6591.00
46_E119_D0.6551.00
73_D128_I0.6501.00
27_S32_F0.6481.00
49_F120_F0.6441.00
24_A31_L0.6401.00
48_D90_D0.6370.99
78_T108_T0.6370.99
80_F123_K0.6340.99
69_C126_A0.6270.99
84_P114_W0.6250.99
13_H62_A0.6230.99
28_G127_R0.6220.99
30_L125_I0.6210.99
56_A122_I0.6200.99
48_D119_D0.6130.99
21_Y35_G0.6120.99
56_A120_F0.6100.99
49_F86_N0.6100.99
57_F95_K0.6010.99
33_V60_L0.6000.99
92_M95_K0.6000.99
13_H41_E0.5980.99
38_G47_P0.5950.99
79_S122_I0.5880.99
62_A66_A0.5870.99
82_T111_G0.5840.99
36_Q60_L0.5820.99
29_D128_I0.5800.99
92_M96_N0.5690.99
49_F90_D0.5640.99
58_D62_A0.5610.99
64_L71_F0.5610.99
83_D119_D0.5610.99
23_A63_T0.5580.99
49_F119_D0.5570.99
25_I106_N0.5560.99
31_L63_T0.5560.99
25_I75_I0.5550.99
49_F94_V0.5530.99
22_S25_I0.5340.98
88_F92_M0.5290.98
18_E23_A0.5280.98
26_R67_A0.5270.98
36_Q59_N0.5250.98
74_I77_V0.5250.98
47_P119_D0.5210.98
88_F116_A0.5200.98
63_T66_A0.5170.98
27_S30_L0.5160.98
64_L124_V0.5160.98
69_C127_R0.5140.98
34_S106_N0.5090.98
55_L62_A0.5070.97
76_D108_T0.5060.97
76_D106_N0.5000.97
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1pf5A 3 0.9847 100 0.185 Contact Map
3vczA 5 0.9237 100 0.188 Contact Map
2b33A 3 0.9389 100 0.19 Contact Map
3k0tA 3 0.9313 100 0.193 Contact Map
1xrgA 3 0.9389 100 0.195 Contact Map
1jd1A 3 0.9466 100 0.197 Contact Map
3quwA 3 0.9389 100 0.198 Contact Map
1qd9A 3 0.9313 100 0.202 Contact Map
2cvlA 3 0.9313 100 0.203 Contact Map
3l7qA 3 0.9237 100 0.204 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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