GREMLIN Database
YJFM - Uncharacterized protein YjfM
UniProt: P39295 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG12488
Length: 212 (172)
Sequences: 284 (214)
Seq/√Len: 16.3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
105_N198_G3.4120.99
72_A76_D3.3890.99
105_N114_K3.0440.99
97_A100_A2.8220.98
49_A88_A2.8000.97
134_F138_R2.7190.97
37_Q40_L2.5540.96
36_A41_T2.4080.94
91_W95_K2.3070.92
74_V78_I2.3060.92
163_W166_T2.2790.92
78_I88_A2.2430.91
126_S130_V2.1480.89
130_V137_S1.9980.85
128_I135_L1.9060.83
181_S184_S1.9040.82
115_Y204_S1.8870.82
137_S141_R1.8840.82
184_S205_S1.8760.82
40_L45_M1.8010.79
202_R206_A1.7960.79
75_Q96_T1.7480.77
36_A39_Y1.6990.74
106_M109_Q1.6700.73
147_P152_S1.6530.72
189_T194_T1.6350.71
91_W191_K1.6270.71
57_S165_S1.6230.71
59_S85_D1.6180.71
171_S204_S1.5570.68
106_M135_L1.5520.67
128_I139_V1.5410.67
164_R168_G1.5230.66
107_T116_E1.5200.66
50_F136_L1.4840.64
35_Y42_L1.4630.63
98_F204_S1.4540.62
194_T197_R1.4440.62
34_R43_A1.4350.61
71_Y80_D1.3930.59
35_Y43_A1.3860.58
50_F127_W1.3800.58
191_K202_R1.3720.58
42_L51_F1.3690.57
41_T104_K1.3640.57
102_V200_Y1.3550.57
57_S206_A1.3450.56
97_A101_D1.3450.56
77_C129_P1.3430.56
77_C87_C1.3430.56
111_C129_P1.3430.56
77_C111_C1.3430.56
87_C111_C1.3430.56
87_C129_P1.3430.56
53_L56_C1.3220.55
75_Q79_D1.3160.54
92_N127_W1.3100.54
44_L107_T1.2890.53
73_T195_V1.2640.51
197_R207_R1.2550.51
180_E183_S1.2480.50
148_F153_G1.2310.49
94_A118_C1.2160.48
166_T172_W1.1810.46
128_I137_S1.1770.46
40_L44_L1.1720.46
102_V110_N1.1550.45
188_T207_R1.1310.43
48_A143_D1.1160.43
118_C129_P1.1150.43
87_C118_C1.1150.43
77_C118_C1.1150.43
111_C118_C1.1150.43
92_N95_K1.1080.42
42_L45_M1.0970.42
130_V140_I1.0950.41
50_F66_G1.0930.41
122_N131_V1.0880.41
66_G127_W1.0790.41
110_N114_K1.0730.40
161_P166_T1.0730.40
165_S171_S1.0710.40
123_V128_I1.0670.40
73_T76_D1.0570.39
47_G205_S1.0490.39
114_K191_K1.0460.39
70_F127_W1.0410.38
127_W130_V1.0290.38
74_V194_T1.0160.37
88_A209_H0.9930.36
131_V209_H0.9900.36
103_P133_G0.9900.36
161_P168_G0.9850.35
72_A86_I0.9820.35
59_S107_T0.9770.35
52_V109_Q0.9640.34
68_G127_W0.9610.34
45_M54_K0.9500.33
176_S186_G0.9490.33
98_F172_W0.9450.33
125_Q142_K0.9410.33
115_Y134_F0.9400.33
69_T128_I0.9390.33
172_W177_G0.9390.33
150_Y168_G0.9290.32
192_A207_R0.9270.32
142_K145_D0.9210.32
151_N154_G0.9200.32
105_N200_Y0.9130.32
126_S132_S0.9120.32
71_Y153_G0.8970.31
102_V105_N0.8950.31
58_D146_E0.8930.31
43_A93_N0.8720.30
75_Q117_N0.8710.30
91_W105_N0.8600.29
87_C199_G0.8580.29
111_C199_G0.8580.29
129_P199_G0.8580.29
77_C199_G0.8580.29
42_L195_V0.8540.29
68_G135_L0.8530.29
139_V142_K0.8500.28
45_M164_R0.8470.28
101_D157_F0.8430.28
53_L112_Q0.8330.28
55_G143_D0.8310.28
55_G205_S0.8300.28
46_G186_G0.8260.27
101_D114_K0.8240.27
49_A108_Q0.8240.27
83_N86_I0.8180.27
144_R209_H0.8170.27
164_R204_S0.8000.26
69_T123_V0.7980.26
131_V187_F0.7970.26
50_F53_L0.7970.26
161_P204_S0.7950.26
179_K182_Y0.7950.26
103_P115_Y0.7940.26
71_Y168_G0.7920.26
95_K99_Y0.7910.26
76_D197_R0.7900.26
90_G175_G0.7890.26
124_E140_I0.7860.26
38_K192_A0.7800.25
130_V208_G0.7800.25
91_W195_V0.7760.25
99_Y107_T0.7760.25
117_N151_N0.7740.25
43_A53_L0.7640.25
73_T93_N0.7610.24
94_A203_S0.7590.24
144_R206_A0.7540.24
71_Y138_R0.7520.24
52_V175_G0.7480.24
47_G136_L0.7470.24
48_A173_R0.7450.24
117_N144_R0.7410.24
105_N185_G0.7390.23
93_N108_Q0.7390.23
96_T99_Y0.7360.23
84_A195_V0.7330.23
83_N203_S0.7310.23
109_Q113_S0.7250.23
108_Q127_W0.7250.23
48_A153_G0.7240.23
178_K185_G0.7240.23
125_Q140_I0.7240.23
66_G91_W0.7170.23
100_A208_G0.7170.23
108_Q186_G0.7070.22
44_L136_L0.7040.22
73_T134_F0.7040.22
57_S130_V0.6980.22
70_F112_Q0.6970.22
137_S140_I0.6970.22
102_V170_Y0.6950.22
167_S208_G0.6920.22
70_F179_K0.6880.21
91_W172_W0.6860.21
71_Y163_W0.6860.21
81_G184_S0.6800.21
189_T192_A0.6800.21
130_V134_F0.6740.21
74_V164_R0.6700.21
129_P133_G0.6670.21
87_C133_G0.6670.21
111_C133_G0.6670.21
77_C133_G0.6670.21
77_C201_G0.6480.20
129_P201_G0.6480.20
87_C201_G0.6480.20
111_C201_G0.6480.20
167_S204_S0.6240.19
107_T190_K0.6220.19
173_R176_S0.6210.19
179_K183_S0.6190.19
115_Y165_S0.6190.19
125_Q130_V0.6190.19
118_C199_G0.6180.19
96_T113_S0.6160.19
68_G192_A0.6140.19
67_D195_V0.6140.19
125_Q203_S0.6140.19
47_G55_G0.6040.18
168_G171_S0.6020.18
39_Y43_A0.6000.18
52_V169_D0.5980.18
96_T185_G0.5970.18
74_V196_S0.5950.18
89_R96_T0.5920.18
58_D68_G0.5890.18
72_A194_T0.5880.18
48_A135_L0.5870.18
47_G160_R0.5870.18
132_S136_L0.5840.18
57_S196_S0.5820.18
34_R37_Q0.5810.17
79_D107_T0.5780.17
112_Q132_S0.5770.17
146_E159_S0.5710.17
147_P205_S0.5690.17
76_D168_G0.5650.17
147_P153_G0.5630.17
49_A142_K0.5630.17
131_V157_F0.5620.17
130_V138_R0.5610.17
109_Q139_V0.5590.17
43_A134_F0.5580.17
34_R48_A0.5570.17
58_D76_D0.5550.17
136_L160_R0.5540.17
166_T169_D0.5520.17
109_Q119_Y0.5470.16
112_Q194_T0.5430.16
146_E183_S0.5410.16
106_M127_W0.5400.16
55_G103_P0.5330.16
158_A162_V0.5320.16
98_F150_Y0.5220.16
46_G138_R0.5180.15
37_Q44_L0.5170.15
135_L192_A0.5160.15
163_W174_S0.5110.15
88_A100_A0.5090.15
85_D156_S0.5090.15
107_T110_N0.5080.15
107_T183_S0.5070.15
54_K176_S0.5050.15
45_M60_S0.5050.15
81_G84_A0.5050.15
109_Q183_S0.5040.15
85_D122_N0.5030.15
42_L74_V0.5030.15
127_W140_I0.5020.15
179_K205_S0.5010.15
162_V166_T0.5000.15
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4kysA 1 0.217 20.3 0.954 Contact Map
1oahA 2 0.5755 12.2 0.959 Contact Map
3zbiC 1 0.0943 7.7 0.962 Contact Map
4fasA 3 0.0991 4.9 0.966 Contact Map
4mvfA 1 0.1698 2.2 0.971 Contact Map
2vozA 3 0.3726 1.8 0.972 Contact Map
2mi9A 1 0.1226 1.8 0.972 Contact Map
4r2fA 1 0.6038 1.8 0.972 Contact Map
2cmyB 1 0.0896 1.7 0.973 Contact Map
3j61R 1 0.2264 1.6 0.973 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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