GREMLIN Database
YJFK - Uncharacterized protein YjfK
UniProt: P39293 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG12486
Length: 219 (205)
Sequences: 121 (91)
Seq/√Len: 6.3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
110_E114_R4.2400.96
134_W138_F2.5290.67
61_I93_I2.4720.65
4_F9_F2.4580.64
123_G136_R2.4190.63
6_Q12_D2.4060.63
21_P49_P2.3710.61
155_V165_V2.3380.60
73_Y170_M2.3060.59
107_I116_A2.2700.58
34_T51_E2.2700.58
99_F134_W2.2140.56
23_G189_E2.1810.55
116_A202_F2.1200.52
35_L104_S2.1130.52
79_F205_A2.1130.52
60_H70_F2.0930.51
68_Q215_L2.0690.51
27_N138_F2.0520.50
80_L198_P1.9780.47
26_L57_A1.9690.47
35_L74_T1.9500.46
183_Y209_D1.8920.44
127_L136_R1.8910.44
35_L149_V1.8810.44
104_S201_L1.8600.43
55_V59_S1.8290.42
61_I82_I1.7990.41
174_R184_L1.7220.38
24_L63_L1.6990.37
64_G155_V1.6790.37
7_R92_D1.6010.34
11_K93_I1.5930.34
6_Q10_G1.5860.34
61_I151_M1.5710.33
22_L29_G1.5530.33
15_P80_L1.5490.32
172_Y214_S1.5370.32
82_I131_E1.5280.32
107_I158_Q1.5220.32
58_V172_Y1.5200.31
6_Q13_N1.5180.31
136_R140_S1.4940.31
27_N82_I1.4820.30
146_I214_S1.4570.30
97_K183_Y1.4370.29
25_H106_G1.4280.29
38_R69_I1.4000.28
53_F69_I1.3990.28
90_I146_I1.3970.28
136_R207_G1.3870.27
107_I126_T1.3580.27
45_L130_Q1.3550.27
12_D17_I1.3520.26
9_F12_D1.3380.26
13_N133_R1.3340.26
69_I210_I1.3120.25
183_Y210_I1.3090.25
44_L185_L1.2820.24
92_D191_S1.2700.24
62_D212_L1.2670.24
66_G177_T1.2560.24
10_G157_N1.2440.23
72_Y83_N1.2400.23
72_Y76_G1.2350.23
32_L62_D1.2320.23
65_G197_E1.2230.23
55_V104_S1.2230.23
109_K125_M1.2150.23
71_R170_M1.2100.23
101_Y203_S1.2090.23
86_G107_I1.1970.22
14_K154_K1.1890.22
151_M169_T1.1860.22
68_Q213_T1.1860.22
21_P38_R1.1770.22
79_F209_D1.1750.22
138_F171_G1.1690.22
24_L98_L1.1680.22
91_D215_L1.1650.21
28_S37_F1.1630.21
163_W167_N1.1620.21
157_N167_N1.1510.21
14_K85_T1.1420.21
123_G199_E1.1240.20
74_T166_H1.1230.20
131_E135_Q1.1150.20
32_L57_A1.1120.20
77_D206_L1.1080.20
37_F99_F1.1070.20
29_G80_L1.0950.20
139_N172_Y1.0930.20
69_I115_E1.0900.20
53_F205_A1.0860.20
5_F67_S1.0790.19
68_Q84_T1.0690.19
10_G13_N1.0610.19
113_W117_I1.0610.19
123_G215_L1.0510.19
91_D156_E1.0430.19
25_H165_V1.0410.19
8_L11_K1.0320.18
55_V149_V1.0230.18
91_D172_Y1.0170.18
114_R179_D1.0160.18
8_L34_T1.0120.18
66_G161_A1.0120.18
72_Y122_M0.9980.18
80_L184_L0.9970.18
64_G212_L0.9960.18
20_G72_Y0.9940.18
73_Y149_V0.9840.17
50_G206_L0.9830.17
21_P123_G0.9830.17
59_S127_L0.9760.17
39_L122_M0.9630.17
148_P188_G0.9580.17
142_E186_L0.9560.17
106_G127_L0.9540.17
71_R153_E0.9520.17
81_Q153_E0.9510.17
137_F173_Q0.9490.17
17_I43_E0.9450.17
111_S178_E0.9450.17
76_G210_I0.9430.17
4_F8_L0.9390.16
171_G176_V0.9350.16
76_G189_E0.9330.16
60_H68_Q0.9330.16
74_T167_N0.9300.16
116_A158_Q0.9290.16
90_I93_I0.9290.16
95_D137_F0.9210.16
7_R32_L0.9180.16
110_E126_T0.9170.16
18_A82_I0.9130.16
68_Q91_D0.9100.16
45_L128_N0.9080.16
12_D179_D0.9020.16
153_E182_E0.8980.16
84_T213_T0.8890.15
89_D110_E0.8870.15
15_P178_E0.8850.15
67_S72_Y0.8810.15
148_P170_M0.8760.15
97_K173_Q0.8730.15
6_Q108_S0.8730.15
13_N111_S0.8720.15
116_A145_N0.8710.15
92_D215_L0.8700.15
187_N204_R0.8690.15
99_F123_G0.8680.15
97_K146_I0.8570.15
4_F11_K0.8560.15
5_F109_K0.8550.15
33_D76_G0.8450.15
23_G80_L0.8430.15
47_A126_T0.8430.15
135_Q210_I0.8400.15
86_G152_L0.8240.14
45_L132_K0.8220.14
135_Q203_S0.8200.14
152_L166_H0.8170.14
24_L86_G0.8110.14
87_G99_F0.8080.14
31_T206_L0.8050.14
187_N210_I0.8050.14
65_G112_H0.8030.14
26_L173_Q0.8010.14
99_F112_H0.8000.14
80_L202_F0.8000.14
59_S75_S0.7970.14
6_Q61_I0.7950.14
22_L95_D0.7950.14
175_Q215_L0.7940.14
139_N146_I0.7920.14
52_E167_N0.7900.14
185_L207_G0.7890.14
199_E213_T0.7890.14
72_Y170_M0.7860.14
93_I199_E0.7850.14
19_R166_H0.7810.14
39_L113_W0.7800.13
75_S210_I0.7770.13
10_G111_S0.7740.13
74_T168_F0.7720.13
182_E185_L0.7720.13
28_S172_Y0.7680.13
192_F198_P0.7680.13
43_E72_Y0.7650.13
104_S203_S0.7640.13
74_T151_M0.7630.13
4_F176_V0.7630.13
14_K130_Q0.7520.13
112_H197_E0.7500.13
106_G214_S0.7460.13
113_W200_W0.7410.13
4_F69_I0.7400.13
92_D123_G0.7360.13
19_R75_S0.7340.13
30_F173_Q0.7320.13
58_V190_E0.7270.13
81_Q171_G0.7230.13
154_K164_E0.7210.13
68_Q92_D0.7210.13
86_G106_G0.7180.12
10_G14_K0.7160.12
89_D92_D0.7130.12
59_S189_E0.7130.12
24_L111_S0.7120.12
42_D131_E0.7070.12
35_L166_H0.7070.12
41_E168_F0.7060.12
57_A98_L0.7040.12
97_K137_F0.7040.12
13_N92_D0.7020.12
26_L118_N0.6990.12
108_S147_E0.6990.12
6_Q69_I0.6980.12
128_N183_Y0.6970.12
153_E174_R0.6950.12
134_W171_G0.6930.12
12_D162_K0.6910.12
4_F123_G0.6850.12
72_Y104_S0.6820.12
20_G166_H0.6710.12
13_N115_E0.6710.12
80_L136_R0.6690.12
4_F108_S0.6630.12
80_L216_H0.6620.12
19_R74_T0.6590.12
34_T131_E0.6560.12
58_V68_Q0.6530.11
92_D186_L0.6520.11
74_T152_L0.6490.11
25_H157_N0.6430.11
170_M190_E0.6400.11
94_D161_A0.6400.11
136_R147_E0.6390.11
165_V206_L0.6380.11
59_S76_G0.6350.11
39_L86_G0.6300.11
66_G176_V0.6270.11
156_E185_L0.6240.11
57_A161_A0.6220.11
9_F136_R0.6210.11
44_L151_M0.6190.11
63_L95_D0.6170.11
49_P123_G0.6130.11
122_M197_E0.6130.11
26_L66_G0.6080.11
52_E76_G0.6080.11
177_T215_L0.6060.11
55_V67_S0.6020.11
209_D215_L0.6010.11
39_L190_E0.5980.11
16_A111_S0.5980.11
39_L107_I0.5980.11
21_P144_G0.5970.11
206_L212_L0.5960.11
48_L206_L0.5960.11
109_K127_L0.5950.11
30_F55_V0.5890.11
82_I93_I0.5880.11
123_G147_E0.5840.10
26_L106_G0.5800.10
155_V173_Q0.5740.10
69_I212_L0.5730.10
64_G98_L0.5710.10
79_F90_I0.5700.10
24_L101_Y0.5700.10
60_H162_K0.5690.10
128_N209_D0.5670.10
5_F112_H0.5640.10
38_R97_K0.5640.10
22_L215_L0.5630.10
108_S123_G0.5620.10
9_F176_V0.5610.10
15_P133_R0.5590.10
24_L79_F0.5580.10
153_E207_G0.5570.10
95_D186_L0.5550.10
109_K162_K0.5520.10
4_F213_T0.5470.10
41_E151_M0.5470.10
129_W203_S0.5450.10
121_A126_T0.5360.10
67_S94_D0.5350.10
5_F200_W0.5320.10
10_G134_W0.5320.10
165_V203_S0.5300.10
52_E55_V0.5280.10
96_I155_V0.5240.10
11_K122_M0.5200.10
24_L77_D0.5190.10
62_D185_L0.5190.10
4_F22_L0.5160.10
48_L51_E0.5160.10
147_E172_Y0.5150.10
8_L136_R0.5120.10
27_N59_S0.5100.10
14_K112_H0.5050.09
21_P167_N0.5040.09
69_I205_A0.5040.09
9_F213_T0.5030.09
150_Y202_F0.5020.09
4_F12_D0.5010.09
76_G170_M0.5000.09
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1qahA 3 0.1918 20.6 0.962 Contact Map
2cwjA 3 0.1735 12.4 0.965 Contact Map
2ewcA 5 0.1826 12.1 0.965 Contact Map
2ig8A 3 0.2146 11.8 0.966 Contact Map
3u7vA 3 0.4155 8.9 0.968 Contact Map
3lmeA 3 0.1826 8.2 0.968 Contact Map
4aboI 1 0.1233 7.5 0.969 Contact Map
1reqB 1 0.5205 6.2 0.97 Contact Map
3kjjA 3 0.1872 5.6 0.97 Contact Map
3pzlA 5 0.2009 4 0.972 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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