YJEM - ECOLI - GREMLIN Contacts

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YJEM - Inner membrane transporter YjeM

UniProt:	P39282	Sequences: MPHTIKKMSLIGLILMIFTSVFGFANSPSAYYLMGYSAIPFYIFSALLFFIPFALMMAEMGAAYRKEEGGIYSWMNNSVGPRFAFIGTFMWFSSYIIWMVSTSAKVWVPFSTFLYGSDMTQHWRIAGLEPTQVVGLLAVAWMILVTVVASKGINKIARITAVGGIAVMCLNLVLLLVSITILLLNGGHFAQDINFLASPNPGYQSGLAMLSFVVFAIFAYGGIEAVGGLVDKTENPEKNFAKGIVFAAIVISIGYSLAIFLWGVSTNWQQVLSNGSVNLGNITYVLMKSLGMTLGNALHLSPEASLSLGVWFARITGLSMFLAYTGAFFTLCYSPLKAIIQGTPKALWPEPMTRLNAMGMPSIAMWMQCGLVTVFILLVSFGGGTASAFFNKLTLMANVSMTLPYLFLALAFPFFKARQDLDRPFVIFKTHLSAMIATVVVVLVVTFANVFTIIQPVVEAGDWDSTLWMIGGPVFFSLLAMAIYQNYCSRVAKNPQWAVE	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG12475
Length:	500 (429)
Sequences:	24701 (16607)
Seq/√Len:	801.8

ECOLI - YJEM YCAM GADC YGJI GABP LYSP ANSP YIFK AROP MMUP POTE PROY FRLA PHEP PUUP CYCA PLAP YJEH ADIC YBAT CADB ARCD
BACSU - ROCC YBXG YBEC YBGF HUTM GABP AAPA YTNA ROCE ASPP YHDG YVBW YDGF YFNA ARCD STET YCGH YECA YDAO GERBB YNDE GERAB GERKB
HALSA - Q9HHU7 Q9HQB3 Q9HSL5
SULSO - Q97WS3 Q97X49 Q7LXI7 Q97U05 Q97XM0 Q97ZB5 Q97Z63 Q97VA6 Q97U33 Q97VA8 Q97WD4 Q97VR4 Q97Y76 Q97YX9 Q97YN3 Q97U39

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
146_T	369_C	4.392	1.00
351_P	363_I	4.357	1.00
414_F	418_R	3.454	1.00
354_R	363_I	3.125	1.00
238_K	242_K	3.072	1.00
9_S	234_E	2.903	1.00
72_Y	345_K	2.786	1.00
235_N	238_K	2.667	1.00
233_T	239_N	2.641	1.00
43_I	47_L	2.637	1.00
88_T	342_G	2.630	1.00
406_L	438_T	2.604	1.00
356_N	362_S	2.539	1.00
343_T	353_T	2.535	1.00
139_V	373_T	2.519	1.00
14_I	246_F	2.502	1.00
285_V	288_K	2.470	1.00
351_P	354_R	2.451	1.00
178_S	261_L	2.425	1.00
231_D	344_P	2.386	1.00
311_W	315_I	2.321	1.00
59_E	416_K	2.316	1.00
42_Y	45_S	2.313	1.00
176_L	180_T	2.279	1.00
10_L	246_F	2.255	1.00
76_N	84_A	2.169	1.00
340_I	344_P	2.152	1.00
232_K	337_K	2.150	1.00
147_V	151_K	2.129	1.00
366_W	370_G	2.088	1.00
154_N	158_R	2.069	1.00
46_A	252_S	2.052	1.00
285_V	289_S	2.037	1.00
146_T	365_M	2.031	1.00
10_L	14_I	2.022	1.00
143_I	373_T	2.019	1.00
150_S	362_S	2.016	1.00
13_L	233_T	1.999	1.00
10_L	239_N	1.993	1.00
435_M	439_V	1.962	1.00
409_A	437_A	1.932	1.00
139_V	376_I	1.926	1.00
76_N	81_P	1.921	1.00
165_I	169_C	1.917	1.00
79_V	414_F	1.890	1.00
14_I	250_V	1.888	1.00
352_M	367_M	1.887	1.00
242_K	246_F	1.881	1.00
9_S	12_G	1.879	1.00
56_M	409_A	1.877	1.00
138_A	376_I	1.863	1.00
47_L	51_I	1.855	1.00
346_A	350_E	1.819	1.00
92_F	368_Q	1.818	1.00
39_I	42_Y	1.812	1.00
79_V	410_L	1.805	1.00
267_N	270_Q	1.744	1.00
143_I	369_C	1.739	1.00
478_L	482_A	1.734	1.00
12_G	161_A	1.729	1.00
451_F	455_Q	1.724	1.00
235_N	239_N	1.718	1.00
245_V	249_I	1.708	1.00
42_Y	47_L	1.707	1.00
75_M	87_G	1.700	1.00
431_H	435_M	1.699	1.00
356_N	360_M	1.687	1.00
281_N	285_V	1.687	1.00
169_C	173_V	1.667	1.00
450_V	454_I	1.641	1.00
87_G	407_F	1.636	1.00
8_M	12_G	1.633	1.00
42_Y	49_F	1.632	1.00
39_I	43_I	1.627	1.00
477_S	480_A	1.613	1.00
149_A	329_F	1.596	1.00
448_A	452_T	1.594	1.00
150_S	366_W	1.584	1.00
432_L	436_I	1.581	1.00
270_Q	289_S	1.571	1.00
358_M	362_S	1.567	1.00
103_S	328_F	1.564	1.00
80_G	83_F	1.559	1.00
142_M	372_V	1.552	1.00
449_N	452_T	1.552	1.00
17_I	247_A	1.536	1.00
282_I	286_L	1.535	1.00
452_T	455_Q	1.530	1.00
249_I	253_I	1.530	1.00
99_M	372_V	1.528	1.00
410_L	438_T	1.524	1.00
133_V	136_L	1.506	1.00
5_I	359_G	1.503	1.00
229_L	333_Y	1.457	1.00
414_F	417_A	1.445	1.00
43_I	49_F	1.440	1.00
282_I	291_G	1.439	1.00
42_Y	50_F	1.432	1.00
110_F	137_L	1.431	1.00
363_I	367_M	1.425	1.00
170_L	319_S	1.424	1.00
335_P	368_Q	1.423	1.00
235_N	242_K	1.419	1.00
54_A	248_A	1.406	1.00
474_V	478_L	1.406	1.00
42_Y	46_A	1.404	1.00
151_K	358_M	1.403	1.00
339_I	364_A	1.398	1.00
430_T	434_A	1.393	1.00
476_F	480_A	1.389	1.00
472_G	476_F	1.389	1.00
68_E	231_D	1.378	1.00
340_I	355_L	1.377	1.00
37_S	209_M	1.368	1.00
106_V	141_W	1.364	1.00
336_L	365_M	1.362	1.00
103_S	142_M	1.362	1.00
350_E	354_R	1.358	1.00
472_G	475_F	1.357	1.00
314_R	318_L	1.356	1.00
43_I	50_F	1.353	1.00
288_K	313_A	1.351	1.00
146_T	366_W	1.350	1.00
350_E	353_T	1.349	1.00
268_W	271_V	1.336	1.00
82_R	481_M	1.335	1.00
12_G	157_A	1.333	1.00
142_M	369_C	1.331	1.00
447_F	451_F	1.330	1.00
22_F	25_A	1.329	1.00
179_I	261_L	1.327	1.00
282_I	285_V	1.325	1.00
410_L	414_F	1.320	1.00
465_S	476_F	1.316	1.00
139_V	143_I	1.312	1.00
75_M	407_F	1.308	1.00
64_Y	77_N	1.302	1.00
286_L	291_G	1.296	1.00
106_V	321_F	1.295	1.00
198_S	201_P	1.294	1.00
449_N	453_I	1.291	1.00
354_R	362_S	1.286	1.00
432_L	435_M	1.282	1.00
79_V	83_F	1.273	1.00
470_I	474_V	1.267	1.00
444_V	448_A	1.262	1.00
168_M	172_L	1.261	1.00
41_F	212_F	1.250	1.00
10_L	242_K	1.239	1.00
53_F	409_A	1.236	1.00
464_D	467_L	1.234	1.00
54_A	244_I	1.231	1.00
175_L	257_L	1.231	1.00
339_I	348_W	1.227	1.00
38_A	42_Y	1.225	1.00
283_T	291_G	1.225	1.00
473_P	477_S	1.218	1.00
434_A	438_T	1.217	1.00
429_K	433_S	1.215	1.00
253_I	257_L	1.210	1.00
188_H	192_D	1.210	1.00
145_V	328_F	1.207	1.00
468_W	472_G	1.207	1.00
456_P	459_E	1.206	1.00
477_S	481_M	1.201	1.00
236_P	241_A	1.201	1.00
73_S	77_N	1.198	1.00
431_H	434_A	1.191	1.00
102_T	327_A	1.189	1.00
425_F	428_F	1.186	1.00
447_F	450_V	1.185	1.00
78_S	411_A	1.184	1.00
21_V	251_I	1.180	1.00
200_N	203_Y	1.170	1.00
8_M	13_L	1.163	1.00
283_T	286_L	1.163	1.00
13_L	243_G	1.161	1.00
174_L	178_S	1.159	1.00
239_N	242_K	1.156	1.00
189_F	192_D	1.149	1.00
37_S	200_N	1.141	1.00
445_V	448_A	1.137	1.00
443_L	447_F	1.134	1.00
8_M	157_A	1.134	1.00
191_Q	194_N	1.124	1.00
55_L	245_V	1.122	1.00
17_I	226_V	1.119	1.00
466_T	470_I	1.115	1.00
195_F	200_N	1.113	1.00
419_Q	423_R	1.107	1.00
455_Q	458_V	1.100	1.00
41_F	49_F	1.099	1.00
63_A	423_R	1.099	1.00
57_M	71_I	1.098	1.00
355_L	359_G	1.094	1.00
291_G	309_G	1.094	1.00
234_E	239_N	1.090	1.00
182_L	264_V	1.090	1.00
288_K	310_V	1.088	1.00
75_M	83_F	1.086	1.00
18_F	250_V	1.083	1.00
200_N	204_Q	1.082	1.00
178_S	265_S	1.078	1.00
471_G	475_F	1.078	1.00
11_I	15_L	1.075	1.00
135_G	139_V	1.075	1.00
160_T	329_F	1.070	1.00
40_P	43_I	1.070	1.00
363_I	366_W	1.063	1.00
413_P	435_M	1.063	1.00
173_V	177_V	1.061	1.00
72_Y	341_Q	1.061	1.00
92_F	339_I	1.058	1.00
148_V	159_I	1.057	1.00
450_V	453_I	1.055	1.00
43_I	46_A	1.054	1.00
85_F	89_F	1.054	1.00
63_A	421_L	1.050	1.00
42_Y	48_L	1.049	1.00
445_V	449_N	1.045	1.00
61_G	74_W	1.045	1.00
452_T	457_V	1.044	1.00
439_V	443_L	1.043	1.00
146_T	150_S	1.041	1.00
419_Q	422_D	1.040	1.00
39_I	260_F	1.032	1.00
446_T	449_N	1.021	1.00
370_G	374_V	1.017	1.00
433_S	437_A	1.013	1.00
291_G	312_F	1.013	1.00
189_F	194_N	1.010	1.00
159_I	163_G	1.010	1.00
107_W	137_L	1.009	1.00
448_A	454_I	1.008	1.00
475_F	479_L	1.007	1.00
451_F	456_P	1.006	1.00
7_K	234_E	1.005	1.00
140_A	144_L	1.005	1.00
221_G	401_M	1.005	1.00
56_M	434_A	1.000	1.00
440_V	444_V	0.998	1.00
201_P	204_Q	0.997	1.00
110_F	321_F	0.997	1.00
283_T	287_M	0.995	1.00
344_P	353_T	0.995	1.00
172_L	176_L	0.994	1.00
163_G	326_G	0.994	1.00
429_K	432_L	0.994	1.00
38_A	41_F	0.992	1.00
195_F	198_S	0.989	1.00
16_M	229_L	0.988	1.00
462_D	476_F	0.984	1.00
430_T	433_S	0.983	1.00
197_A	200_N	0.978	1.00
188_H	191_Q	0.978	1.00
18_F	251_I	0.973	1.00
143_I	147_V	0.967	1.00
158_R	162_V	0.962	1.00
110_F	114_L	0.959	1.00
150_S	360_M	0.957	1.00
332_C	369_C	0.955	1.00
195_F	199_P	0.954	1.00
47_L	436_I	0.954	1.00
153_I	333_Y	0.943	1.00
441_V	444_V	0.935	1.00
168_M	254_G	0.927	1.00
463_W	467_L	0.927	1.00
452_T	456_P	0.925	1.00
80_G	482_A	0.922	1.00
136_L	140_A	0.921	1.00
412_F	434_A	0.920	1.00
59_E	62_A	0.918	1.00
444_V	449_N	0.914	1.00
309_G	312_F	0.912	1.00
144_L	325_T	0.910	1.00
41_F	45_S	0.908	1.00
268_W	272_L	0.908	1.00
453_I	456_P	0.903	1.00
175_L	261_L	0.903	1.00
465_S	468_W	0.902	1.00
406_L	410_L	0.893	1.00
451_F	454_I	0.891	1.00
45_S	49_F	0.889	1.00
224_E	228_G	0.889	1.00
101_S	218_F	0.885	1.00
76_N	345_K	0.882	1.00
479_L	482_A	0.879	1.00
101_S	394_T	0.877	1.00
469_M	473_P	0.874	1.00
474_V	477_S	0.868	1.00
11_I	161_A	0.868	1.00
476_F	482_A	0.865	1.00
167_V	323_A	0.864	1.00
444_V	451_F	0.864	1.00
39_I	49_F	0.861	1.00
310_V	314_R	0.860	1.00
62_A	424_P	0.855	1.00
465_S	472_G	0.854	1.00
287_M	291_G	0.853	1.00
211_S	215_F	0.853	1.00
448_A	451_F	0.852	1.00
45_S	50_F	0.849	1.00
230_V	240_F	0.848	1.00
107_W	138_A	0.847	1.00
362_S	366_W	0.846	1.00
450_V	455_Q	0.842	1.00
23_G	27_S	0.840	1.00
471_G	474_V	0.840	1.00
196_L	200_N	0.839	1.00
274_N	285_V	0.838	1.00
246_F	250_V	0.838	1.00
36_Y	39_I	0.837	1.00
352_M	363_I	0.836	1.00
286_L	289_S	0.832	1.00
369_C	373_T	0.831	1.00
447_F	453_I	0.830	1.00
28_P	105_K	0.828	1.00
69_G	72_Y	0.826	1.00
420_D	423_R	0.826	1.00
12_G	158_R	0.824	1.00
15_L	161_A	0.824	1.00
462_D	465_S	0.823	1.00
434_A	437_A	0.823	1.00
145_V	329_F	0.820	1.00
180_T	184_L	0.819	1.00
150_S	356_N	0.819	1.00
63_A	424_P	0.818	1.00
444_V	452_T	0.815	1.00
82_R	86_I	0.815	1.00
260_F	264_V	0.814	1.00
89_F	348_W	0.813	1.00
7_K	154_N	0.813	1.00
46_A	220_Y	0.811	1.00
442_V	446_T	0.809	1.00
60_M	412_F	0.807	1.00
190_A	194_N	0.806	1.00
467_L	471_G	0.804	1.00
452_T	458_V	0.804	1.00
406_L	442_V	0.802	1.00
348_W	352_M	0.801	1.00
179_I	183_L	0.800	1.00
197_A	201_P	0.797	1.00
267_N	289_S	0.796	1.00
471_G	477_S	0.794	1.00
444_V	447_F	0.794	1.00
36_Y	263_G	0.793	1.00
107_W	134_V	0.793	1.00
175_L	179_I	0.792	1.00
22_F	27_S	0.790	1.00
69_G	73_S	0.784	1.00
446_T	450_V	0.783	1.00
454_I	457_V	0.783	1.00
270_Q	273_S	0.782	1.00
476_F	481_M	0.782	1.00
135_G	376_I	0.779	1.00
356_N	359_G	0.774	1.00
200_N	209_M	0.771	1.00
106_V	324_Y	0.767	1.00
147_V	150_S	0.762	1.00
225_A	334_S	0.761	1.00
137_L	140_A	0.761	1.00
37_S	40_P	0.759	1.00
452_T	459_E	0.759	1.00
183_L	186_G	0.758	1.00
478_L	481_M	0.758	1.00
284_Y	288_K	0.756	1.00
142_M	376_I	0.756	1.00
467_L	470_I	0.756	1.00
75_M	411_A	0.755	1.00
449_N	455_Q	0.754	1.00
281_N	286_L	0.753	1.00
465_S	474_V	0.748	1.00
252_S	256_S	0.748	1.00
435_M	438_T	0.744	1.00
10_L	243_G	0.744	1.00
158_R	161_A	0.743	1.00
23_G	28_P	0.743	1.00
470_I	477_S	0.742	1.00
351_P	367_M	0.740	1.00
89_F	472_G	0.739	1.00
40_P	44_F	0.737	1.00
468_W	476_F	0.736	1.00
83_F	407_F	0.733	1.00
269_Q	273_S	0.733	1.00
440_V	443_L	0.732	1.00
184_L	187_G	0.730	1.00
184_L	192_D	0.728	1.00
189_F	193_I	0.724	1.00
204_Q	209_M	0.721	1.00
106_V	325_T	0.720	1.00
451_F	458_V	0.719	1.00
104_A	393_L	0.718	1.00
265_S	286_L	0.717	1.00
111_S	134_V	0.716	1.00
46_A	50_F	0.715	1.00
46_A	49_F	0.714	1.00
41_F	46_A	0.712	1.00
433_S	436_I	0.711	1.00
455_Q	459_E	0.709	1.00
68_E	340_I	0.709	1.00
174_L	287_M	0.707	1.00
447_F	452_T	0.707	1.00
180_T	183_L	0.706	1.00
476_F	479_L	0.705	1.00
283_T	288_K	0.703	1.00
448_A	453_I	0.702	1.00
151_K	155_K	0.701	1.00
66_K	77_N	0.701	1.00
470_I	473_P	0.698	1.00
467_L	472_G	0.698	1.00
187_G	192_D	0.695	1.00
423_R	426_V	0.688	1.00
282_I	290_L	0.686	1.00
413_P	417_A	0.685	1.00
241_A	244_I	0.684	1.00
41_F	48_L	0.683	1.00
96_I	371_L	0.681	1.00
114_L	117_S	0.681	1.00
449_N	456_P	0.680	1.00
45_S	216_A	0.679	1.00
396_M	400_S	0.675	1.00
412_F	416_K	0.675	1.00
468_W	471_G	0.674	1.00
45_S	48_L	0.673	1.00
416_K	419_Q	0.672	1.00
370_G	373_T	0.671	1.00
37_S	42_Y	0.671	1.00
357_A	362_S	0.667	1.00
180_T	186_G	0.667	1.00
145_V	332_C	0.666	1.00
198_S	202_G	0.666	1.00
221_G	405_Y	0.666	1.00
60_M	74_W	0.666	1.00
421_L	424_P	0.666	1.00
231_D	340_I	0.666	1.00
269_Q	272_L	0.665	1.00
78_S	414_F	0.663	1.00
157_A	161_A	0.663	1.00
91_W	95_Y	0.663	1.00
117_S	133_V	0.663	1.00
179_I	257_L	0.662	1.00
199_P	203_Y	0.662	1.00
7_K	153_I	0.661	1.00
51_I	436_I	0.660	1.00
337_K	340_I	0.660	1.00
430_T	435_M	0.658	1.00
19_T	164_G	0.657	1.00
18_F	164_G	0.656	1.00
281_N	284_Y	0.654	1.00
33_L	36_Y	0.653	1.00
41_F	44_F	0.653	1.00
98_W	397_A	0.652	1.00
57_M	408_L	0.652	1.00
469_M	472_G	0.651	1.00
315_I	319_S	0.650	1.00
339_I	367_M	0.649	1.00
100_V	393_L	0.646	1.00
246_F	249_I	0.645	1.00
311_W	314_R	0.645	1.00
427_I	430_T	0.644	1.00
440_V	451_F	0.642	1.00
90_M	404_P	0.642	1.00
22_F	26_N	0.642	1.00
100_V	375_F	0.640	1.00
175_L	258_A	0.638	1.00
468_W	480_A	0.637	1.00
155_K	158_R	0.636	1.00
208_A	211_S	0.635	1.00
43_I	256_S	0.632	1.00
14_I	243_G	0.632	1.00
450_V	456_P	0.632	1.00
135_G	138_A	0.632	1.00
467_L	477_S	0.631	1.00
11_I	158_R	0.631	1.00
196_L	199_P	0.628	1.00
149_A	333_Y	0.626	1.00
182_L	261_L	0.626	1.00
149_A	365_M	0.625	1.00
462_D	466_T	0.624	1.00
437_A	441_V	0.623	1.00
150_S	358_M	0.623	1.00
37_S	41_F	0.622	1.00
22_F	167_V	0.621	1.00
284_Y	287_M	0.621	1.00
282_I	287_M	0.619	1.00
39_I	263_G	0.619	1.00
66_K	73_S	0.619	1.00
94_S	401_M	0.618	1.00
43_I	48_L	0.616	1.00
438_T	442_V	0.616	1.00
257_L	261_L	0.613	1.00
417_A	431_H	0.613	1.00
20_S	330_T	0.612	1.00
78_S	415_F	0.610	1.00
468_W	473_P	0.609	1.00
250_V	254_G	0.609	1.00
187_G	193_I	0.608	1.00
166_A	319_S	0.606	1.00
98_W	101_S	0.606	1.00
177_V	181_I	0.606	1.00
199_P	202_G	0.603	1.00
72_Y	76_N	0.601	1.00
227_G	244_I	0.601	1.00
332_C	336_L	0.600	1.00
141_W	145_V	0.599	1.00
258_A	262_W	0.599	1.00
191_Q	196_L	0.598	1.00
21_V	247_A	0.597	1.00
465_S	470_I	0.597	1.00
451_F	457_V	0.596	1.00
361_P	364_A	0.595	1.00
7_K	11_I	0.595	1.00
97_I	396_M	0.593	1.00
465_S	469_M	0.593	1.00
475_F	481_M	0.593	1.00
237_E	424_P	0.592	1.00
343_T	352_M	0.592	1.00
352_M	364_A	0.589	1.00
272_L	275_G	0.587	1.00
417_A	420_D	0.586	1.00
422_D	426_V	0.586	1.00
54_A	223_I	0.585	1.00
233_T	240_F	0.584	1.00
448_A	455_Q	0.584	1.00
467_L	474_V	0.583	1.00
400_S	404_P	0.583	1.00
145_V	325_T	0.583	1.00
446_T	453_I	0.582	1.00
23_G	26_N	0.582	1.00
61_G	227_G	0.581	1.00
221_G	224_E	0.581	1.00
285_V	291_G	0.580	1.00
110_F	141_W	0.579	1.00
464_D	473_P	0.579	1.00
355_L	358_M	0.578	1.00
235_N	241_A	0.578	1.00
261_L	264_V	0.578	1.00
14_I	17_I	0.578	1.00
107_W	110_F	0.577	1.00
336_L	364_A	0.576	1.00
413_P	438_T	0.575	1.00
337_K	361_P	0.574	1.00
188_H	193_I	0.574	1.00
281_N	287_M	0.574	1.00
447_F	455_Q	0.573	1.00
39_I	46_A	0.573	1.00
79_V	411_A	0.572	1.00
447_F	454_I	0.569	1.00
240_F	244_I	0.567	1.00
95_Y	331_L	0.565	1.00
72_Y	88_T	0.564	1.00
411_A	415_F	0.563	1.00
271_V	282_I	0.563	1.00
113_F	318_L	0.560	1.00
281_N	288_K	0.560	1.00
446_T	451_F	0.560	1.00
432_L	437_A	0.559	1.00
166_A	170_L	0.558	1.00
150_S	365_M	0.557	1.00
71_I	224_E	0.557	1.00
22_F	254_G	0.557	1.00
177_V	309_G	0.556	1.00
232_K	355_L	0.556	1.00
36_Y	268_W	0.555	1.00
139_V	377_L	0.554	1.00
232_K	361_P	0.553	1.00
109_P	320_M	0.553	1.00
271_V	274_N	0.551	1.00
270_Q	274_N	0.550	1.00
38_A	259_I	0.549	1.00
39_I	47_L	0.549	1.00
112_T	317_G	0.549	1.00
446_T	452_T	0.548	1.00
18_F	21_V	0.548	1.00
237_E	422_D	0.547	1.00
423_R	427_I	0.545	1.00
143_I	146_T	0.545	1.00
141_W	328_F	0.544	1.00
250_V	253_I	0.539	1.00
178_S	182_L	0.538	1.00
281_N	291_G	0.538	1.00
196_L	201_P	0.535	1.00
11_I	14_I	0.534	1.00
156_I	333_Y	0.533	1.00
60_M	78_S	0.533	1.00
459_E	464_D	0.533	1.00
72_Y	84_A	0.531	1.00
70_G	227_G	0.531	1.00
177_V	291_G	0.530	1.00
443_L	451_F	0.529	1.00
155_K	159_I	0.529	1.00
58_A	62_A	0.529	1.00
436_I	440_V	0.529	1.00
451_F	459_E	0.528	1.00
38_A	49_F	0.528	1.00
20_S	225_A	0.528	1.00
87_G	404_P	0.526	1.00
54_A	58_A	0.526	1.00
427_I	434_A	0.526	1.00
17_I	21_V	0.526	1.00
454_I	458_V	0.525	1.00
157_A	329_F	0.525	1.00
190_A	193_I	0.525	1.00
228_G	334_S	0.525	1.00
335_P	339_I	0.525	1.00
142_M	373_T	0.524	1.00
464_D	468_W	0.524	1.00
102_T	328_F	0.524	1.00
152_G	155_K	0.522	1.00
470_I	481_M	0.520	1.00
164_G	167_V	0.520	1.00
221_G	397_A	0.519	1.00
90_M	403_L	0.519	1.00
465_S	473_P	0.519	1.00
20_S	331_L	0.519	1.00
318_L	322_L	0.518	1.00
188_H	194_N	0.518	1.00
40_P	209_M	0.517	1.00
391_N	394_T	0.515	1.00
187_G	191_Q	0.515	1.00
80_G	84_A	0.515	1.00
153_I	229_L	0.514	1.00
113_F	317_G	0.511	1.00
146_T	332_C	0.510	1.00
94_S	97_I	0.509	1.00
468_W	475_F	0.509	1.00
42_Y	51_I	0.508	1.00
468_W	479_L	0.508	1.00
6_K	234_E	0.508	1.00
469_M	476_F	0.507	1.00
448_A	456_P	0.507	1.00
468_W	474_V	0.506	1.00
367_M	371_L	0.506	1.00
96_I	368_Q	0.506	1.00
323_A	326_G	0.505	1.00
466_T	479_L	0.505	1.00
71_I	228_G	0.505	1.00
60_M	415_F	0.504	1.00
105_K	109_P	0.503	1.00
90_M	94_S	0.503	1.00
473_P	476_F	0.503	1.00
161_A	165_I	0.503	1.00
30_A	259_I	0.502	1.00
453_I	457_V	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3l1lA	2	0.842	100	0.358	Contact Map
4djkA	2	0.866	100	0.386	Contact Map
3giaA	1	0.858	100	0.394	Contact Map
3dh4A	3	0.856	98.8	0.872	Contact Map
2xq2A	2	0.858	98.7	0.877	Contact Map
2jlnA	1	0.83	97.9	0.901	Contact Map
4wgvA	2	0.732	97.8	0.904	Contact Map
2a65A	2	0.892	97.7	0.906	Contact Map
4xp4A	1	0.904	97.2	0.913	Contact Map
4us3A	1	0.816	96.1	0.924	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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