GREMLIN Database
FIMI - Fimbrin-like protein FimI
UniProt: P39264 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG11974
Length: 179 (165)
Sequences: 3504 (2765)
Seq/√Len: 215.3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
106_V120_G3.0951.00
117_T164_T3.0891.00
121_V154_A3.0101.00
44_R82_E2.8561.00
122_A155_K2.8561.00
124_F155_K2.7231.00
91_V176_L2.7221.00
66_A69_E2.7191.00
77_V149_S2.6821.00
122_A157_R2.6761.00
107_L133_I2.5371.00
46_E81_R2.4261.00
109_V168_A2.3041.00
156_Y168_A2.2751.00
79_H149_S2.2601.00
118_N163_V2.2461.00
125_D129_N2.2411.00
121_V170_A2.1341.00
128_G153_I2.1261.00
65_H69_E2.0941.00
107_L172_A2.0561.00
115_I167_I1.9061.00
77_V151_H1.8281.00
73_P155_K1.8201.00
46_E79_H1.8071.00
132_P135_R1.8051.00
122_A130_L1.7521.00
97_G107_L1.7051.00
75_P153_I1.6681.00
70_D122_A1.6551.00
46_E49_D1.6281.00
59_I71_S1.5821.00
106_V157_R1.5821.00
26_T29_G1.5811.00
96_H134_N1.5781.00
100_D159_T1.5631.00
96_H175_S1.5311.00
57_G74_V1.4411.00
15_M18_L1.4221.00
57_G168_A1.4211.00
105_D132_P1.3901.00
70_D155_K1.3681.00
75_P151_H1.3631.00
37_V58_Q1.3391.00
52_M78_I1.3261.00
92_G177_T1.2991.00
56_M156_Y1.2971.00
76_F123_L1.2921.00
12_L15_M1.2831.00
49_D79_H1.2831.00
67_V161_R1.2481.00
49_D52_M1.2391.00
14_P17_A1.2301.00
44_R81_R1.2291.00
57_G72_A1.2071.00
143_L146_G1.1981.00
64_F158_A1.1861.00
66_A158_A1.1841.00
54_V76_F1.1761.00
22_K26_T1.1591.00
106_V122_A1.1561.00
91_V148_T1.1531.00
19_A23_W1.1351.00
65_H158_A1.1211.00
70_D124_F1.1171.00
123_L172_A1.1141.00
13_L16_F1.1061.00
95_F152_F1.1061.00
56_M168_A1.1051.00
93_V150_L1.0991.00
101_G120_G1.0831.00
70_D157_R1.0681.00
56_M121_V1.0551.00
30_G34_F1.0531.00
40_A61_S1.0521.00
101_G104_P1.0491.00
15_M20_G1.0491.00
158_A161_R1.0281.00
94_A136_P1.0221.00
64_F69_E1.0201.00
92_G179_Q1.0141.00
64_F163_V1.0111.00
63_R71_S1.0101.00
73_P153_I0.9971.00
60_S63_R0.9941.00
33_Q171_Q0.9911.00
78_I174_F0.9881.00
64_F119_I0.9631.00
143_L148_T0.9601.00
21_N25_T0.9601.00
59_I168_A0.9501.00
100_D104_P0.9431.00
99_A105_D0.9401.00
116_A119_I0.9380.99
64_F159_T0.9380.99
16_F19_A0.9370.99
158_A163_V0.9290.99
126_D151_H0.9250.99
17_A21_N0.9160.99
94_A177_T0.9080.99
124_F153_I0.8920.99
95_F123_L0.8900.99
16_F20_G0.8850.99
30_G174_F0.8810.99
120_G159_T0.8790.99
107_L170_A0.8780.99
12_L16_F0.8690.99
47_A50_K0.8670.99
17_A20_G0.8620.99
52_M174_F0.8570.99
110_G171_Q0.8540.99
59_I64_F0.8510.99
22_K25_T0.8470.99
119_I156_Y0.8460.99
59_I156_Y0.8340.99
142_R145_S0.8230.99
20_G23_W0.8060.98
20_G25_T0.8040.98
114_G167_I0.8020.98
18_L21_N0.7960.98
99_A133_I0.7940.98
121_V168_A0.7890.98
123_L133_I0.7890.98
77_V99_A0.7880.98
100_D103_N0.7830.98
80_L148_T0.7790.98
35_Q53_T0.7650.98
18_L22_K0.7630.98
129_N138_A0.7560.98
19_A22_K0.7540.98
25_T28_P0.7530.98
47_A52_M0.7510.98
95_F174_F0.7470.97
137_P152_F0.7450.97
97_G100_D0.7410.97
84_S87_V0.7400.97
124_F130_L0.7380.97
35_Q55_N0.7380.97
137_P140_W0.7320.97
131_V137_P0.7320.97
21_N24_N0.7280.97
13_L17_A0.7280.97
81_R147_S0.7260.97
109_V114_G0.7160.97
38_I163_V0.7140.97
15_M19_A0.7120.97
56_M154_A0.7050.96
23_W27_L0.7050.96
23_W26_T0.7030.96
110_G169_N0.7020.96
98_V108_S0.7020.96
19_A24_N0.6970.96
25_T29_G0.6910.96
61_S165_G0.6910.96
12_L20_G0.6890.96
42_T156_Y0.6790.96
142_R147_S0.6760.96
20_G24_N0.6720.95
73_P124_F0.6710.95
90_R142_R0.6700.95
102_K105_D0.6690.95
67_V160_G0.6680.95
70_D73_P0.6660.95
67_V158_A0.6630.95
56_M122_A0.6560.95
109_V169_N0.6550.95
55_N156_Y0.6540.95
61_S163_V0.6500.94
21_N26_T0.6480.94
24_N28_P0.6460.94
109_V119_I0.6460.94
56_M74_V0.6440.94
132_P137_P0.6440.94
86_V89_E0.6430.94
40_A84_S0.6410.94
135_R138_A0.6390.94
14_P18_L0.6390.94
69_E158_A0.6380.94
39_I84_S0.6360.94
57_G169_N0.6340.94
16_F23_W0.6330.94
71_S156_Y0.6320.94
91_V143_L0.6310.94
79_H147_S0.6270.93
100_D120_G0.6220.93
55_N74_V0.6220.93
22_K29_G0.6160.93
38_I109_V0.6160.93
118_N162_R0.6150.93
92_G136_P0.6120.93
110_G115_I0.6050.92
14_P20_G0.6050.92
84_S124_F0.6010.92
118_N160_G0.6010.92
38_I59_I0.6000.92
13_L18_L0.5990.92
100_D108_S0.5970.92
156_Y169_N0.5970.92
67_V118_N0.5950.91
118_N159_T0.5840.91
22_K27_L0.5840.91
31_N51_Q0.5810.90
124_F128_G0.5800.90
30_G36_G0.5780.90
109_V170_A0.5770.90
20_G26_T0.5760.90
15_M25_T0.5760.90
131_V152_F0.5750.90
97_G171_Q0.5740.90
133_I170_A0.5720.90
105_D130_L0.5720.90
96_H173_W0.5680.89
158_A162_R0.5670.89
124_F157_R0.5640.89
54_V154_A0.5610.89
94_A135_R0.5580.89
15_M21_N0.5570.89
100_D160_G0.5540.88
30_G37_V0.5530.88
63_R72_A0.5480.88
17_A22_K0.5460.88
87_V172_A0.5450.87
42_T84_S0.5450.87
71_S155_K0.5410.87
87_V93_V0.5360.87
103_N106_V0.5350.86
103_N134_N0.5330.86
90_R179_Q0.5300.86
84_S143_L0.5300.86
33_Q53_T0.5290.86
56_M59_I0.5250.85
127_E153_I0.5250.85
119_I163_V0.5250.85
127_E140_W0.5240.85
12_L17_A0.5230.85
93_V176_L0.5210.85
17_A25_T0.5200.85
56_M155_K0.5180.85
33_Q51_Q0.5170.85
53_T173_W0.5160.84
46_E147_S0.5160.84
109_V116_A0.5110.84
133_I152_F0.5110.84
95_F131_V0.5100.84
143_L147_S0.5090.84
28_P31_N0.5070.83
120_G132_P0.5010.83
20_G27_L0.5000.83
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2jmrA 1 0.8492 100 0.255 Contact Map
2jtyA 1 0.8715 100 0.272 Contact Map
2xg5B 1 0.7821 100 0.276 Contact Map
2uy6B 2 0.8045 100 0.294 Contact Map
1pdkB 1 0.7765 100 0.305 Contact Map
3bwuF 1 0.6983 100 0.344 Contact Map
4dwhB 1 0.7542 99.9 0.375 Contact Map
2w07B 1 0.6536 99.9 0.378 Contact Map
3bfqG 1 0.7374 99.9 0.38 Contact Map
5afoA 1 0.9609 99.9 0.389 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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