GREMLIN Database
YTFJ - Uncharacterized protein YtfJ
UniProt: P39187 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG12510
Length: 184 (179)
Sequences: 210 (132)
Seq/√Len: 9.9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
34_I137_A7.3321.00
163_K171_E4.7851.00
65_Q150_V4.0240.99
160_Q182_L2.8310.90
37_R133_S2.6500.87
89_L176_M2.2910.77
23_F162_A2.2180.75
94_Y127_S2.1790.73
63_V152_V2.1330.72
62_R97_T2.0870.70
80_L175_V2.0720.69
81_I85_K2.0170.67
77_N148_S1.9200.63
75_E78_A1.9030.62
138_L145_E1.8680.61
23_F159_V1.8570.60
13_L42_L1.8090.58
7_L17_M1.7980.58
20_A99_I1.7900.57
102_T128_Q1.7370.55
66_H128_Q1.7280.55
138_L153_L1.6740.52
114_R131_V1.6680.52
64_L150_V1.6670.52
66_H102_T1.6480.51
33_G151_V1.6330.50
11_C79_T1.6230.50
79_T124_Y1.5680.47
64_L67_I1.5420.46
100_V164_D1.5340.46
12_L117_L1.5320.46
66_H137_A1.4940.44
16_M19_S1.4650.43
64_L109_S1.4400.42
27_Q31_P1.4360.42
107_P128_Q1.4360.42
86_S174_Q1.4330.41
120_N129_F1.4260.41
82_E85_K1.4250.41
34_I140_A1.3870.39
71_T116_S1.3830.39
22_Q30_P1.3720.39
103_D113_V1.3640.38
85_K153_L1.3620.38
127_S183_L1.3430.37
154_D158_R1.3380.37
144_D152_V1.3370.37
49_Y98_T1.3340.37
120_N124_Y1.3230.37
63_V179_L1.3190.36
15_P63_V1.3190.36
69_G74_K1.3060.36
73_A171_E1.2890.35
73_A81_I1.2830.35
100_V161_W1.2800.35
59_G167_L1.2700.34
58_V176_M1.2660.34
23_F30_P1.2650.34
54_S66_H1.2520.34
15_P90_P1.2480.34
76_K160_Q1.2430.33
152_V175_V1.2180.32
117_L131_V1.2170.32
102_T131_V1.2140.32
24_E27_Q1.2130.32
111_M115_S1.1900.31
32_I178_L1.1820.31
49_Y118_E1.1790.31
71_T150_V1.1690.30
88_K91_H1.1660.30
11_C41_V1.1620.30
21_H162_A1.1560.30
23_F137_A1.1330.29
151_V182_L1.1190.29
30_P136_V1.1090.28
31_P151_V1.1060.28
22_Q32_I1.0990.28
168_T171_E1.0870.27
97_T112_F1.0770.27
138_L161_W1.0700.27
170_E179_L1.0660.27
108_G121_K1.0610.26
107_P129_F1.0550.26
95_Q167_L1.0400.26
110_G145_E1.0310.25
76_K145_E1.0310.25
19_S92_D1.0300.25
28_R159_V1.0280.25
129_F179_L1.0230.25
18_A92_D1.0220.25
90_P126_W1.0130.25
76_K124_Y1.0110.25
6_I170_E1.0080.25
66_H96_T1.0080.25
96_T127_S1.0040.24
102_T107_P0.9970.24
166_A172_V0.9920.24
65_Q124_Y0.9820.24
129_F164_D0.9720.23
100_V117_L0.9630.23
107_P130_I0.9580.23
69_G84_I0.9540.23
24_E50_K0.9470.23
57_L153_L0.9290.22
160_Q179_L0.9260.22
73_A149_A0.9210.22
47_F131_V0.9210.22
76_K144_D0.9170.22
55_A151_V0.9050.21
84_I183_L0.9030.21
100_V110_G0.9020.21
7_L64_L0.9010.21
18_A64_L0.8930.21
128_Q182_L0.8900.21
80_L133_S0.8850.21
29_V72_S0.8840.21
109_S150_V0.8800.21
47_F114_R0.8800.21
10_T27_Q0.8740.20
93_R166_A0.8720.20
176_M183_L0.8660.20
109_S127_S0.8630.20
122_K149_A0.8630.20
43_D46_Q0.8530.20
106_I148_S0.8520.20
62_R95_Q0.8510.20
66_H75_E0.8390.19
11_C14_L0.8350.19
14_L134_N0.8280.19
119_S172_V0.8270.19
8_A13_L0.8260.19
128_Q131_V0.8260.19
29_V153_L0.8250.19
17_M156_D0.8250.19
94_Y119_S0.8250.19
34_I84_I0.8220.19
122_K154_D0.8180.19
6_I122_K0.8140.19
94_Y109_S0.8140.19
29_V129_F0.8120.19
81_I153_L0.8090.18
42_L47_F0.8080.18
8_A162_A0.8020.18
71_T127_S0.8000.18
6_I64_L0.7910.18
25_T32_I0.7910.18
7_L171_E0.7910.18
90_P149_A0.7900.18
94_Y137_A0.7770.18
44_K170_E0.7740.18
79_T123_L0.7700.17
94_Y115_S0.7690.17
49_Y121_K0.7690.17
79_T120_N0.7680.17
55_A140_A0.7650.17
75_E96_T0.7620.17
35_T154_D0.7600.17
33_G55_A0.7580.17
9_L12_L0.7580.17
120_N183_L0.7560.17
62_R128_Q0.7540.17
107_P146_E0.7490.17
70_R104_D0.7480.17
57_L73_A0.7480.17
43_D159_V0.7410.17
32_I137_A0.7400.17
62_R112_F0.7360.17
122_K151_V0.7290.16
107_P111_M0.7280.16
77_N165_G0.7250.16
171_E180_Q0.7230.16
66_H138_L0.7120.16
79_T107_P0.7110.16
55_A156_D0.7110.16
136_V140_A0.7100.16
116_S119_S0.7090.16
119_S147_S0.7020.16
6_I14_L0.7020.16
10_T82_E0.7010.16
81_I176_M0.7010.16
108_G113_V0.7000.16
100_V127_S0.7000.16
14_L168_T0.6990.16
76_K79_T0.6980.16
124_Y133_S0.6940.16
48_S100_V0.6910.15
73_A147_S0.6870.15
34_I120_N0.6780.15
107_P115_S0.6760.15
84_I116_S0.6760.15
22_Q148_S0.6670.15
89_L179_L0.6660.15
109_S113_V0.6620.15
36_D47_F0.6620.15
84_I127_S0.6600.15
46_Q181_K0.6550.15
46_Q117_L0.6520.15
144_D156_D0.6490.14
94_Y124_Y0.6480.14
102_T117_L0.6440.14
90_P147_S0.6410.14
113_V135_G0.6380.14
11_C180_Q0.6350.14
16_M63_V0.6320.14
45_D134_N0.6300.14
10_T183_L0.6280.14
5_K11_C0.6270.14
45_D75_E0.6210.14
42_L91_H0.6190.14
7_L177_D0.6140.14
78_A84_I0.6130.14
62_R152_V0.6120.14
154_D160_Q0.5950.13
34_I43_D0.5910.13
66_H153_L0.5870.13
75_E82_E0.5840.13
14_L17_M0.5830.13
113_V121_K0.5800.13
91_H173_Q0.5800.13
111_M128_Q0.5800.13
76_K119_S0.5770.13
10_T17_M0.5770.13
43_D178_L0.5760.13
17_M180_Q0.5660.13
82_E86_S0.5650.13
19_S31_P0.5630.13
19_S45_D0.5620.13
40_L105_A0.5620.13
27_Q159_V0.5610.13
73_A163_K0.5600.13
7_L10_T0.5590.13
43_D156_D0.5570.13
149_A171_E0.5530.12
8_A27_Q0.5530.12
114_R130_I0.5500.12
170_E177_D0.5460.12
154_D168_T0.5450.12
53_N139_G0.5430.12
76_K134_N0.5420.12
108_G135_G0.5410.12
43_D53_N0.5410.12
134_N154_D0.5360.12
43_D150_V0.5350.12
26_G177_D0.5340.12
26_G107_P0.5330.12
40_L133_S0.5330.12
95_Q104_D0.5310.12
92_D162_A0.5300.12
81_I138_L0.5300.12
46_Q80_L0.5290.12
37_R47_F0.5210.12
8_A134_N0.5200.12
81_I164_D0.5200.12
149_A163_K0.5190.12
32_I69_G0.5170.12
28_R33_G0.5160.12
82_E159_V0.5160.12
35_T134_N0.5150.12
23_F57_L0.5150.12
12_L80_L0.5130.12
136_V181_K0.5110.12
76_K179_L0.5110.12
13_L111_M0.5110.12
127_S137_A0.5080.12
29_V33_G0.5050.12
75_E116_S0.5030.11
177_D181_K0.5020.11
10_T177_D0.5000.11
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3gknA 1 0.788 98.6 0.869 Contact Map
2hyxA 2 0.8967 98.5 0.874 Contact Map
2ls5A 1 0.8098 98.3 0.881 Contact Map
2yzhA 3 0.8533 98.2 0.883 Contact Map
4nmuA 2 0.7989 98.2 0.883 Contact Map
3ixrA 1 0.7989 98.1 0.886 Contact Map
2b1kA 1 0.7826 98.1 0.886 Contact Map
1qmvA 3 0.8315 98.1 0.886 Contact Map
4gqcA 4 0.7826 98.1 0.886 Contact Map
2bmxA 3 0.8587 98.1 0.887 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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