TORT - ECOLI - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

TORT - Periplasmic protein TorT

UniProt:	P38683	Sequences: MRVLLFLLLSLFMLPAFSADNLLRWHDAQHFTVQASTPLKAKRAWKLCALYPSLKDSYWLSLNYGMQEAARRYGVDLKVLEAGGYSQLATQQAQIDQCKQWGAEAILLGSSTTSFPDLQKQVASLPVIELVNAIDAPQVKSRVGVPWFQMGYQPGRYLVQWAHGKPLNVLLMPGPDNAGGSKEMVEGFRAAIAGSPVRIVDIALGDNDIEIQRNLLQEMLERHPEIDVVAGTAIAAEAAMGEGRNLKTPLTVVSFYLSHQVYRGLKRGRVIMAASDQMVWQGELAVEQAIRQLQGQSVSDNVSPPILVLTPKNADREHIRRSLSPGGFRPVYFYQHTSAAKK	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG12616
Length:	342 (294)
Sequences:	37549 (27966)
Seq/√Len:	1631.0

ECOLI - TORT LACI ASCG GALS PURR CRA IDNR CYTR RBSR GALR MALI GNTR YCJW LSRB XYLF RBSB TRER ALSB EBGR YTFQ ARAF YPHF DGAL XYLR
BACSU - RBSR CCPA KDGR DEGA YKVZ NTDR MSMR EXUR YVDE RBSB GANR CCPB ARAR

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
148_F	190_A	3.406	1.00
166_P	227_D	3.305	1.00
105_A	289_A	2.683	1.00
154_P	253_V	2.667	1.00
185_V	189_R	2.563	1.00
257_L	275_S	2.523	1.00
166_P	251_T	2.501	1.00
141_S	292_Q	2.493	1.00
152_Y	194_G	2.282	1.00
15_P	19_A	2.232	1.00
69_A	72_R	2.225	1.00
23_L	27_D	2.184	1.00
19_A	23_L	2.164	1.00
69_A	287_E	2.145	1.00
213_R	245_N	2.139	1.00
152_Y	190_A	2.111	1.00
159_V	195_S	2.108	1.00
156_R	191_A	2.085	1.00
152_Y	191_A	2.057	1.00
284_L	287_E	2.054	1.00
217_Q	246_L	2.014	1.00
70_A	286_V	2.000	1.00
149_Q	153_Q	1.982	1.00
217_Q	242_E	1.967	1.00
150_M	255_F	1.958	1.00
65_G	282_G	1.948	1.00
151_G	155_G	1.940	1.00
148_F	186_E	1.925	1.00
212_Q	238_A	1.917	1.00
158_L	228_V	1.910	1.00
156_R	160_Q	1.893	1.00
243_G	250_L	1.884	1.00
69_A	283_E	1.867	1.00
18_S	22_L	1.798	1.00
155_G	188_F	1.766	1.00
151_G	230_A	1.765	1.00
161_W	314_A	1.763	1.00
275_S	307_L	1.754	1.00
68_E	279_V	1.745	1.00
291_R	296_Q	1.740	1.00
48_C	103_A	1.732	1.00
152_Y	156_R	1.718	1.00
170_L	226_I	1.707	1.00
216_L	239_A	1.702	1.00
221_E	246_L	1.680	1.00
199_I	202_I	1.670	1.00
213_R	242_E	1.655	1.00
231_G	239_A	1.635	1.00
277_Q	280_W	1.630	1.00
156_R	195_S	1.630	1.00
22_L	25_W	1.619	1.00
65_G	279_V	1.615	1.00
69_A	73_Y	1.602	1.00
130_L	285_A	1.596	1.00
284_L	302_V	1.592	1.00
153_Q	306_I	1.583	1.00
244_R	267_R	1.574	1.00
157_Y	161_W	1.569	1.00
168_N	225_E	1.557	1.00
186_E	190_A	1.556	1.00
149_Q	152_Y	1.548	1.00
159_V	191_A	1.518	1.00
22_L	26_H	1.503	1.00
242_E	246_L	1.492	1.00
269_R	312_K	1.480	1.00
73_Y	290_I	1.474	1.00
146_P	149_Q	1.463	1.00
157_Y	160_Q	1.455	1.00
24_R	28_A	1.447	1.00
189_R	193_A	1.429	1.00
242_E	245_N	1.428	1.00
69_A	286_V	1.427	1.00
183_E	186_E	1.423	1.00
280_W	284_L	1.409	1.00
206_D	211_I	1.407	1.00
45_W	104_E	1.407	1.00
290_I	294_Q	1.393	1.00
157_Y	310_T	1.390	1.00
213_R	241_G	1.387	1.00
257_L	311_P	1.386	1.00
280_W	283_E	1.367	1.00
168_N	198_R	1.367	1.00
150_M	306_I	1.363	1.00
155_G	159_V	1.362	1.00
216_L	229_V	1.357	1.00
48_C	98_C	1.356	1.00
168_N	227_D	1.355	1.00
151_G	187_G	1.347	1.00
15_P	18_S	1.344	1.00
155_G	187_G	1.335	1.00
170_L	219_M	1.332	1.00
47_L	70_A	1.323	1.00
217_Q	245_N	1.320	1.00
200_V	203_A	1.313	1.00
213_R	217_Q	1.303	1.00
20_D	24_R	1.301	1.00
155_G	191_A	1.288	1.00
223_H	226_I	1.283	1.00
191_A	194_G	1.283	1.00
45_W	75_V	1.277	1.00
287_E	291_R	1.270	1.00
70_A	77_L	1.270	1.00
216_L	243_G	1.268	1.00
166_P	228_V	1.243	1.00
14_L	17_F	1.241	1.00
187_G	191_A	1.239	1.00
24_R	27_D	1.238	1.00
80_L	94_Q	1.234	1.00
153_Q	156_R	1.234	1.00
148_F	152_Y	1.232	1.00
80_L	98_C	1.227	1.00
107_L	285_A	1.224	1.00
217_Q	221_E	1.219	1.00
66_M	286_V	1.211	1.00
167_L	227_D	1.205	1.00
49_A	66_M	1.204	1.00
238_A	242_E	1.203	1.00
188_F	192_I	1.187	1.00
156_R	194_G	1.179	1.00
240_M	252_V	1.172	1.00
148_F	183_E	1.168	1.00
46_K	76_D	1.168	1.00
171_L	185_V	1.163	1.00
279_V	283_E	1.158	1.00
67_Q	71_R	1.158	1.00
73_Y	287_E	1.149	1.00
17_F	20_D	1.147	1.00
172_M	239_A	1.144	1.00
33_V	39_L	1.141	1.00
46_K	78_K	1.134	1.00
25_W	28_A	1.133	1.00
244_R	269_R	1.133	1.00
66_M	107_L	1.123	1.00
253_V	271_I	1.116	1.00
49_A	77_L	1.114	1.00
157_Y	314_A	1.111	1.00
148_F	187_G	1.106	1.00
168_N	200_V	1.101	1.00
188_F	230_A	1.098	1.00
218_E	222_R	1.098	1.00
169_V	192_I	1.093	1.00
229_V	239_A	1.093	1.00
190_A	194_G	1.090	1.00
210_E	214_N	1.082	1.00
288_Q	302_V	1.077	1.00
208_D	211_I	1.075	1.00
251_T	314_A	1.074	1.00
215_L	218_E	1.068	1.00
71_R	90_T	1.065	1.00
23_L	26_H	1.054	1.00
233_A	273_A	1.051	1.00
212_Q	216_L	1.049	1.00
154_P	230_A	1.048	1.00
282_G	286_V	1.048	1.00
233_A	254_S	1.047	1.00
214_N	218_E	1.045	1.00
19_A	22_L	1.044	1.00
161_W	251_T	1.044	1.00
284_L	288_Q	1.041	1.00
35_A	38_P	1.039	1.00
186_E	189_R	1.030	1.00
182_K	186_E	1.024	1.00
36_S	39_L	1.018	1.00
92_Q	96_D	1.012	1.00
231_G	235_A	1.011	1.00
283_E	287_E	1.004	1.00
168_N	224_P	0.999	1.00
90_T	93_A	0.991	1.00
96_D	100_Q	0.989	1.00
160_Q	195_S	0.982	1.00
73_Y	294_Q	0.981	1.00
75_V	290_I	0.978	1.00
211_I	214_N	0.976	1.00
189_R	199_I	0.975	1.00
161_W	310_T	0.974	1.00
155_G	192_I	0.972	1.00
87_Q	90_T	0.967	1.00
240_M	266_K	0.961	1.00
154_P	274_A	0.956	1.00
191_A	195_S	0.955	1.00
216_L	220_L	0.948	1.00
231_G	236_A	0.948	1.00
289_A	293_L	0.946	1.00
169_V	228_V	0.943	1.00
209_I	241_G	0.939	1.00
284_L	304_P	0.938	1.00
117_D	120_K	0.937	1.00
141_S	288_Q	0.931	1.00
179_G	183_E	0.928	1.00
32_T	37_T	0.927	1.00
64_Y	68_E	0.927	1.00
149_Q	305_P	0.926	1.00
63_N	67_Q	0.923	1.00
72_R	283_E	0.920	1.00
174_G	207_N	0.911	1.00
68_E	283_E	0.906	1.00
307_L	310_T	0.903	1.00
58_Y	278_M	0.900	1.00
33_V	36_S	0.898	1.00
229_V	250_L	0.896	1.00
177_N	182_K	0.895	1.00
205_G	235_A	0.893	1.00
176_D	204_L	0.891	1.00
161_W	166_P	0.889	1.00
49_A	63_N	0.885	1.00
107_L	289_A	0.885	1.00
214_N	217_Q	0.883	1.00
66_M	282_G	0.879	1.00
47_L	107_L	0.878	1.00
277_Q	307_L	0.878	1.00
277_Q	304_P	0.878	1.00
96_D	120_K	0.872	1.00
105_A	293_L	0.868	1.00
146_P	303_S	0.867	1.00
254_S	273_A	0.866	1.00
211_I	215_L	0.865	1.00
275_S	309_L	0.864	1.00
145_V	276_D	0.861	1.00
170_L	229_V	0.859	1.00
159_V	167_L	0.859	1.00
142_R	301_N	0.854	1.00
243_G	252_V	0.854	1.00
145_V	277_Q	0.852	1.00
159_V	197_V	0.848	1.00
220_L	242_E	0.843	1.00
233_A	257_L	0.843	1.00
147_W	184_M	0.841	1.00
143_V	288_Q	0.841	1.00
173_P	185_V	0.833	1.00
68_E	72_R	0.833	1.00
257_L	309_L	0.832	1.00
286_V	290_I	0.821	1.00
256_Y	276_D	0.821	1.00
288_Q	291_R	0.816	1.00
144_G	303_S	0.813	1.00
157_Y	308_V	0.808	1.00
149_Q	306_I	0.807	1.00
92_Q	117_D	0.806	1.00
63_N	79_V	0.805	1.00
190_A	193_A	0.801	1.00
62_L	130_L	0.801	1.00
46_K	101_W	0.799	1.00
116_P	120_K	0.799	1.00
66_M	77_L	0.799	1.00
158_L	253_V	0.796	1.00
144_G	301_N	0.793	1.00
12_F	17_F	0.792	1.00
78_K	103_A	0.790	1.00
34_Q	37_T	0.787	1.00
241_G	244_R	0.787	1.00
44_A	104_E	0.786	1.00
52_P	59_W	0.784	1.00
183_E	187_G	0.781	1.00
233_A	236_A	0.780	1.00
145_V	306_I	0.780	1.00
171_L	230_A	0.777	1.00
16_A	19_A	0.775	1.00
65_G	283_E	0.772	1.00
61_S	279_V	0.768	1.00
64_Y	67_Q	0.766	1.00
31_F	100_Q	0.765	1.00
93_A	96_D	0.763	1.00
216_L	242_E	0.763	1.00
90_T	94_Q	0.762	1.00
78_K	101_W	0.760	1.00
16_A	20_D	0.759	1.00
236_A	254_S	0.758	1.00
157_Y	271_I	0.758	1.00
146_P	305_P	0.758	1.00
172_M	231_G	0.756	1.00
43_R	104_E	0.755	1.00
220_L	246_L	0.742	1.00
216_L	219_M	0.740	1.00
129_E	134_I	0.739	1.00
65_G	69_A	0.737	1.00
83_G	90_T	0.731	1.00
218_E	221_E	0.726	1.00
133_A	301_N	0.725	1.00
50_L	94_Q	0.724	1.00
205_G	211_I	0.722	1.00
48_C	106_I	0.721	1.00
197_V	201_D	0.717	1.00
105_A	128_I	0.713	1.00
99_K	125_L	0.711	1.00
152_Y	187_G	0.710	1.00
171_L	188_F	0.710	1.00
310_T	314_A	0.710	1.00
198_R	201_D	0.706	1.00
43_R	294_Q	0.705	1.00
119_Q	122_V	0.704	1.00
67_Q	77_L	0.703	1.00
241_G	269_R	0.703	1.00
67_Q	81_E	0.702	1.00
153_Q	274_A	0.697	1.00
222_R	226_I	0.694	1.00
192_I	199_I	0.693	1.00
95_I	106_I	0.693	1.00
227_D	251_T	0.687	1.00
167_L	197_V	0.686	1.00
222_R	225_E	0.683	1.00
47_L	286_V	0.679	1.00
99_K	123_A	0.678	1.00
181_S	207_N	0.678	1.00
257_L	263_R	0.674	1.00
264_G	269_R	0.673	1.00
19_A	26_H	0.671	1.00
237_E	266_K	0.670	1.00
107_L	130_L	0.669	1.00
230_A	253_V	0.668	1.00
216_L	238_A	0.664	1.00
243_G	246_L	0.664	1.00
121_Q	127_V	0.663	1.00
89_A	93_A	0.662	1.00
159_V	192_I	0.661	1.00
128_I	292_Q	0.661	1.00
232_T	256_Y	0.661	1.00
212_Q	215_L	0.658	1.00
56_D	234_I	0.650	1.00
199_I	203_A	0.650	1.00
129_E	139_V	0.644	1.00
158_L	230_A	0.638	1.00
131_V	147_W	0.635	1.00
197_V	200_V	0.634	1.00
232_T	235_A	0.631	1.00
192_I	197_V	0.631	1.00
105_A	285_A	0.629	1.00
61_S	278_M	0.626	1.00
128_I	289_A	0.626	1.00
291_R	295_G	0.625	1.00
20_D	23_L	0.625	1.00
147_W	183_E	0.622	1.00
240_M	244_R	0.620	1.00
230_A	255_F	0.619	1.00
207_N	235_A	0.618	1.00
236_A	270_V	0.616	1.00
263_R	266_K	0.614	1.00
153_Q	157_Y	0.614	1.00
169_V	227_D	0.614	1.00
26_H	29_Q	0.612	1.00
263_R	267_R	0.611	1.00
174_G	181_S	0.610	1.00
44_A	76_D	0.609	1.00
75_V	104_E	0.609	1.00
129_E	142_R	0.607	1.00
241_G	245_N	0.604	1.00
169_V	188_F	0.604	1.00
116_P	119_Q	0.602	1.00
241_G	267_R	0.601	1.00
31_F	35_A	0.601	1.00
269_R	311_P	0.601	1.00
279_V	282_G	0.600	1.00
255_F	276_D	0.600	1.00
31_F	96_D	0.599	1.00
75_V	293_L	0.598	1.00
184_M	276_D	0.595	1.00
128_I	288_Q	0.595	1.00
131_V	180_G	0.594	1.00
47_L	75_V	0.594	1.00
64_Y	279_V	0.593	1.00
47_L	293_L	0.593	1.00
154_P	228_V	0.592	1.00
65_G	278_M	0.590	1.00
80_L	97_Q	0.589	1.00
203_A	222_R	0.589	1.00
88_L	92_Q	0.587	1.00
18_S	21_N	0.586	1.00
237_E	258_S	0.585	1.00
219_M	223_H	0.584	1.00
58_Y	62_L	0.581	1.00
13_M	18_S	0.581	1.00
62_L	278_M	0.580	1.00
303_S	306_I	0.579	1.00
213_R	238_A	0.576	1.00
47_L	105_A	0.575	1.00
98_C	103_A	0.575	1.00
215_L	219_M	0.574	1.00
233_A	258_S	0.574	1.00
152_Y	155_G	0.573	1.00
220_L	243_G	0.572	1.00
231_G	254_S	0.572	1.00
157_Y	253_V	0.571	1.00
168_N	226_I	0.569	1.00
93_A	97_Q	0.567	1.00
128_I	143_V	0.566	1.00
133_A	142_R	0.566	1.00
59_W	109_G	0.566	1.00
247_K	251_T	0.564	1.00
210_E	213_R	0.564	1.00
46_K	104_E	0.562	1.00
82_A	91_Q	0.562	1.00
209_I	238_A	0.561	1.00
37_T	41_A	0.561	1.00
103_A	106_I	0.561	1.00
122_V	127_V	0.556	1.00
288_Q	292_Q	0.554	1.00
106_I	125_L	0.554	1.00
70_A	75_V	0.554	1.00
281_Q	304_P	0.550	1.00
147_W	180_G	0.547	1.00
241_G	264_G	0.546	1.00
188_F	199_I	0.546	1.00
228_V	251_T	0.544	1.00
57_S	234_I	0.543	1.00
168_N	223_H	0.543	1.00
141_S	300_D	0.543	1.00
145_V	150_M	0.542	1.00
94_Q	97_Q	0.540	1.00
131_V	281_Q	0.538	1.00
45_W	294_Q	0.532	1.00
271_I	314_A	0.532	1.00
118_L	121_Q	0.531	1.00
310_T	313_N	0.531	1.00
128_I	285_A	0.531	1.00
122_V	138_Q	0.529	1.00
213_R	216_L	0.527	1.00
236_A	252_V	0.527	1.00
70_A	290_I	0.527	1.00
239_A	243_G	0.526	1.00
144_G	147_W	0.523	1.00
274_A	306_I	0.523	1.00
130_L	281_Q	0.522	1.00
12_F	18_S	0.522	1.00
64_Y	83_G	0.520	1.00
82_A	94_Q	0.520	1.00
38_P	41_A	0.520	1.00
46_K	103_A	0.518	1.00
45_W	293_L	0.518	1.00
97_Q	100_Q	0.518	1.00
245_N	267_R	0.518	1.00
172_M	215_L	0.516	1.00
89_A	92_Q	0.514	1.00
17_F	21_N	0.513	1.00
266_K	269_R	0.511	1.00
44_A	75_V	0.511	1.00
56_D	59_W	0.510	1.00
62_L	282_G	0.509	1.00
258_S	262_Y	0.508	1.00
239_A	252_V	0.507	1.00
117_D	121_Q	0.502	1.00
173_P	204_L	0.501	1.00
271_I	308_V	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3dbiA	2	0.7836	100	0.229	Contact Map
2hsgA	1	0.886	100	0.232	Contact Map
4o5aA	2	0.769	100	0.235	Contact Map
1qpzA	2	0.9211	100	0.239	Contact Map
3bilA	2	0.731	100	0.241	Contact Map
1jyeA	2	0.7719	100	0.242	Contact Map
3ctpA	2	0.7544	100	0.243	Contact Map
3kjxA	2	0.8977	100	0.245	Contact Map
3e3mA	2	0.7602	100	0.246	Contact Map
2o20A	2	0.7778	100	0.25	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0106 seconds.