GREMLIN Database
TORT - Periplasmic protein TorT
UniProt: P38683 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG12616
Length: 342 (294)
Sequences: 37549 (27966)
Seq/√Len: 1631.0

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
148_F190_A3.4061.00
166_P227_D3.3051.00
105_A289_A2.6831.00
154_P253_V2.6671.00
185_V189_R2.5631.00
257_L275_S2.5231.00
166_P251_T2.5011.00
141_S292_Q2.4931.00
152_Y194_G2.2821.00
15_P19_A2.2321.00
69_A72_R2.2251.00
23_L27_D2.1841.00
19_A23_L2.1641.00
69_A287_E2.1451.00
213_R245_N2.1391.00
152_Y190_A2.1111.00
159_V195_S2.1081.00
156_R191_A2.0851.00
152_Y191_A2.0571.00
284_L287_E2.0541.00
217_Q246_L2.0141.00
70_A286_V2.0001.00
149_Q153_Q1.9821.00
217_Q242_E1.9671.00
150_M255_F1.9581.00
65_G282_G1.9481.00
151_G155_G1.9401.00
148_F186_E1.9251.00
212_Q238_A1.9171.00
158_L228_V1.9101.00
156_R160_Q1.8931.00
243_G250_L1.8841.00
69_A283_E1.8671.00
18_S22_L1.7981.00
155_G188_F1.7661.00
151_G230_A1.7651.00
161_W314_A1.7631.00
275_S307_L1.7541.00
68_E279_V1.7451.00
291_R296_Q1.7401.00
48_C103_A1.7321.00
152_Y156_R1.7181.00
170_L226_I1.7071.00
216_L239_A1.7021.00
221_E246_L1.6801.00
199_I202_I1.6701.00
213_R242_E1.6551.00
231_G239_A1.6351.00
277_Q280_W1.6301.00
156_R195_S1.6301.00
22_L25_W1.6191.00
65_G279_V1.6151.00
69_A73_Y1.6021.00
130_L285_A1.5961.00
284_L302_V1.5921.00
153_Q306_I1.5831.00
244_R267_R1.5741.00
157_Y161_W1.5691.00
168_N225_E1.5571.00
186_E190_A1.5561.00
149_Q152_Y1.5481.00
159_V191_A1.5181.00
22_L26_H1.5031.00
242_E246_L1.4921.00
269_R312_K1.4801.00
73_Y290_I1.4741.00
146_P149_Q1.4631.00
157_Y160_Q1.4551.00
24_R28_A1.4471.00
189_R193_A1.4291.00
242_E245_N1.4281.00
69_A286_V1.4271.00
183_E186_E1.4231.00
280_W284_L1.4091.00
206_D211_I1.4071.00
45_W104_E1.4071.00
290_I294_Q1.3931.00
157_Y310_T1.3901.00
213_R241_G1.3871.00
257_L311_P1.3861.00
280_W283_E1.3671.00
168_N198_R1.3671.00
150_M306_I1.3631.00
155_G159_V1.3621.00
216_L229_V1.3571.00
48_C98_C1.3561.00
168_N227_D1.3551.00
151_G187_G1.3471.00
15_P18_S1.3441.00
155_G187_G1.3351.00
170_L219_M1.3321.00
47_L70_A1.3231.00
217_Q245_N1.3201.00
200_V203_A1.3131.00
213_R217_Q1.3031.00
20_D24_R1.3011.00
155_G191_A1.2881.00
223_H226_I1.2831.00
191_A194_G1.2831.00
45_W75_V1.2771.00
287_E291_R1.2701.00
70_A77_L1.2701.00
216_L243_G1.2681.00
166_P228_V1.2431.00
14_L17_F1.2411.00
187_G191_A1.2391.00
24_R27_D1.2381.00
80_L94_Q1.2341.00
153_Q156_R1.2341.00
148_F152_Y1.2321.00
80_L98_C1.2271.00
107_L285_A1.2241.00
217_Q221_E1.2191.00
66_M286_V1.2111.00
167_L227_D1.2051.00
49_A66_M1.2041.00
238_A242_E1.2031.00
188_F192_I1.1871.00
156_R194_G1.1791.00
240_M252_V1.1721.00
148_F183_E1.1681.00
46_K76_D1.1681.00
171_L185_V1.1631.00
279_V283_E1.1581.00
67_Q71_R1.1581.00
73_Y287_E1.1491.00
17_F20_D1.1471.00
172_M239_A1.1441.00
33_V39_L1.1411.00
46_K78_K1.1341.00
25_W28_A1.1331.00
244_R269_R1.1331.00
66_M107_L1.1231.00
253_V271_I1.1161.00
49_A77_L1.1141.00
157_Y314_A1.1111.00
148_F187_G1.1061.00
168_N200_V1.1011.00
188_F230_A1.0981.00
218_E222_R1.0981.00
169_V192_I1.0931.00
229_V239_A1.0931.00
190_A194_G1.0901.00
210_E214_N1.0821.00
288_Q302_V1.0771.00
208_D211_I1.0751.00
251_T314_A1.0741.00
215_L218_E1.0681.00
71_R90_T1.0651.00
23_L26_H1.0541.00
233_A273_A1.0511.00
212_Q216_L1.0491.00
154_P230_A1.0481.00
282_G286_V1.0481.00
233_A254_S1.0471.00
214_N218_E1.0451.00
19_A22_L1.0441.00
161_W251_T1.0441.00
284_L288_Q1.0411.00
35_A38_P1.0391.00
186_E189_R1.0301.00
182_K186_E1.0241.00
36_S39_L1.0181.00
92_Q96_D1.0121.00
231_G235_A1.0111.00
283_E287_E1.0041.00
168_N224_P0.9991.00
90_T93_A0.9911.00
96_D100_Q0.9891.00
160_Q195_S0.9821.00
73_Y294_Q0.9811.00
75_V290_I0.9781.00
211_I214_N0.9761.00
189_R199_I0.9751.00
161_W310_T0.9741.00
155_G192_I0.9721.00
87_Q90_T0.9671.00
240_M266_K0.9611.00
154_P274_A0.9561.00
191_A195_S0.9551.00
216_L220_L0.9481.00
231_G236_A0.9481.00
289_A293_L0.9461.00
169_V228_V0.9431.00
209_I241_G0.9391.00
284_L304_P0.9381.00
117_D120_K0.9371.00
141_S288_Q0.9311.00
179_G183_E0.9281.00
32_T37_T0.9271.00
64_Y68_E0.9271.00
149_Q305_P0.9261.00
63_N67_Q0.9231.00
72_R283_E0.9201.00
174_G207_N0.9111.00
68_E283_E0.9061.00
307_L310_T0.9031.00
58_Y278_M0.9001.00
33_V36_S0.8981.00
229_V250_L0.8961.00
177_N182_K0.8951.00
205_G235_A0.8931.00
176_D204_L0.8911.00
161_W166_P0.8891.00
49_A63_N0.8851.00
107_L289_A0.8851.00
214_N217_Q0.8831.00
66_M282_G0.8791.00
47_L107_L0.8781.00
277_Q307_L0.8781.00
277_Q304_P0.8781.00
96_D120_K0.8721.00
105_A293_L0.8681.00
146_P303_S0.8671.00
254_S273_A0.8661.00
211_I215_L0.8651.00
275_S309_L0.8641.00
145_V276_D0.8611.00
170_L229_V0.8591.00
159_V167_L0.8591.00
142_R301_N0.8541.00
243_G252_V0.8541.00
145_V277_Q0.8521.00
159_V197_V0.8481.00
220_L242_E0.8431.00
233_A257_L0.8431.00
147_W184_M0.8411.00
143_V288_Q0.8411.00
173_P185_V0.8331.00
68_E72_R0.8331.00
257_L309_L0.8321.00
286_V290_I0.8211.00
256_Y276_D0.8211.00
288_Q291_R0.8161.00
144_G303_S0.8131.00
157_Y308_V0.8081.00
149_Q306_I0.8071.00
92_Q117_D0.8061.00
63_N79_V0.8051.00
190_A193_A0.8011.00
62_L130_L0.8011.00
46_K101_W0.7991.00
116_P120_K0.7991.00
66_M77_L0.7991.00
158_L253_V0.7961.00
144_G301_N0.7931.00
12_F17_F0.7921.00
78_K103_A0.7901.00
34_Q37_T0.7871.00
241_G244_R0.7871.00
44_A104_E0.7861.00
52_P59_W0.7841.00
183_E187_G0.7811.00
233_A236_A0.7801.00
145_V306_I0.7801.00
171_L230_A0.7771.00
16_A19_A0.7751.00
65_G283_E0.7721.00
61_S279_V0.7681.00
64_Y67_Q0.7661.00
31_F100_Q0.7651.00
93_A96_D0.7631.00
216_L242_E0.7631.00
90_T94_Q0.7621.00
78_K101_W0.7601.00
16_A20_D0.7591.00
236_A254_S0.7581.00
157_Y271_I0.7581.00
146_P305_P0.7581.00
172_M231_G0.7561.00
43_R104_E0.7551.00
220_L246_L0.7421.00
216_L219_M0.7401.00
129_E134_I0.7391.00
65_G69_A0.7371.00
83_G90_T0.7311.00
218_E221_E0.7261.00
133_A301_N0.7251.00
50_L94_Q0.7241.00
205_G211_I0.7221.00
48_C106_I0.7211.00
197_V201_D0.7171.00
105_A128_I0.7131.00
99_K125_L0.7111.00
152_Y187_G0.7101.00
171_L188_F0.7101.00
310_T314_A0.7101.00
198_R201_D0.7061.00
43_R294_Q0.7051.00
119_Q122_V0.7041.00
67_Q77_L0.7031.00
241_G269_R0.7031.00
67_Q81_E0.7021.00
153_Q274_A0.6971.00
222_R226_I0.6941.00
192_I199_I0.6931.00
95_I106_I0.6931.00
227_D251_T0.6871.00
167_L197_V0.6861.00
222_R225_E0.6831.00
47_L286_V0.6791.00
99_K123_A0.6781.00
181_S207_N0.6781.00
257_L263_R0.6741.00
264_G269_R0.6731.00
19_A26_H0.6711.00
237_E266_K0.6701.00
107_L130_L0.6691.00
230_A253_V0.6681.00
216_L238_A0.6641.00
243_G246_L0.6641.00
121_Q127_V0.6631.00
89_A93_A0.6621.00
159_V192_I0.6611.00
128_I292_Q0.6611.00
232_T256_Y0.6611.00
212_Q215_L0.6581.00
56_D234_I0.6501.00
199_I203_A0.6501.00
129_E139_V0.6441.00
158_L230_A0.6381.00
131_V147_W0.6351.00
197_V200_V0.6341.00
232_T235_A0.6311.00
192_I197_V0.6311.00
105_A285_A0.6291.00
61_S278_M0.6261.00
128_I289_A0.6261.00
291_R295_G0.6251.00
20_D23_L0.6251.00
147_W183_E0.6221.00
240_M244_R0.6201.00
230_A255_F0.6191.00
207_N235_A0.6181.00
236_A270_V0.6161.00
263_R266_K0.6141.00
153_Q157_Y0.6141.00
169_V227_D0.6141.00
26_H29_Q0.6121.00
263_R267_R0.6111.00
174_G181_S0.6101.00
44_A76_D0.6091.00
75_V104_E0.6091.00
129_E142_R0.6071.00
241_G245_N0.6041.00
169_V188_F0.6041.00
116_P119_Q0.6021.00
241_G267_R0.6011.00
31_F35_A0.6011.00
269_R311_P0.6011.00
279_V282_G0.6001.00
255_F276_D0.6001.00
31_F96_D0.5991.00
75_V293_L0.5981.00
184_M276_D0.5951.00
128_I288_Q0.5951.00
131_V180_G0.5941.00
47_L75_V0.5941.00
64_Y279_V0.5931.00
47_L293_L0.5931.00
154_P228_V0.5921.00
65_G278_M0.5901.00
80_L97_Q0.5891.00
203_A222_R0.5891.00
88_L92_Q0.5871.00
18_S21_N0.5861.00
237_E258_S0.5851.00
219_M223_H0.5841.00
58_Y62_L0.5811.00
13_M18_S0.5811.00
62_L278_M0.5801.00
303_S306_I0.5791.00
213_R238_A0.5761.00
47_L105_A0.5751.00
98_C103_A0.5751.00
215_L219_M0.5741.00
233_A258_S0.5741.00
152_Y155_G0.5731.00
220_L243_G0.5721.00
231_G254_S0.5721.00
157_Y253_V0.5711.00
168_N226_I0.5691.00
93_A97_Q0.5671.00
128_I143_V0.5661.00
133_A142_R0.5661.00
59_W109_G0.5661.00
247_K251_T0.5641.00
210_E213_R0.5641.00
46_K104_E0.5621.00
82_A91_Q0.5621.00
209_I238_A0.5611.00
37_T41_A0.5611.00
103_A106_I0.5611.00
122_V127_V0.5561.00
288_Q292_Q0.5541.00
106_I125_L0.5541.00
70_A75_V0.5541.00
281_Q304_P0.5501.00
147_W180_G0.5471.00
241_G264_G0.5461.00
188_F199_I0.5461.00
228_V251_T0.5441.00
57_S234_I0.5431.00
168_N223_H0.5431.00
141_S300_D0.5431.00
145_V150_M0.5421.00
94_Q97_Q0.5401.00
131_V281_Q0.5381.00
45_W294_Q0.5321.00
271_I314_A0.5321.00
118_L121_Q0.5311.00
310_T313_N0.5311.00
128_I285_A0.5311.00
122_V138_Q0.5291.00
213_R216_L0.5271.00
236_A252_V0.5271.00
70_A290_I0.5271.00
239_A243_G0.5261.00
144_G147_W0.5231.00
274_A306_I0.5231.00
130_L281_Q0.5221.00
12_F18_S0.5221.00
64_Y83_G0.5201.00
82_A94_Q0.5201.00
38_P41_A0.5201.00
46_K103_A0.5181.00
45_W293_L0.5181.00
97_Q100_Q0.5181.00
245_N267_R0.5181.00
172_M215_L0.5161.00
89_A92_Q0.5141.00
17_F21_N0.5131.00
266_K269_R0.5111.00
44_A75_V0.5111.00
56_D59_W0.5101.00
62_L282_G0.5091.00
258_S262_Y0.5081.00
239_A252_V0.5071.00
117_D121_Q0.5021.00
173_P204_L0.5011.00
271_I308_V0.5001.00
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3dbiA 2 0.7836 100 0.229 Contact Map
2hsgA 1 0.886 100 0.232 Contact Map
4o5aA 2 0.769 100 0.235 Contact Map
1qpzA 2 0.9211 100 0.239 Contact Map
3bilA 2 0.731 100 0.241 Contact Map
1jyeA 2 0.7719 100 0.242 Contact Map
3ctpA 2 0.7544 100 0.243 Contact Map
3kjxA 2 0.8977 100 0.245 Contact Map
3e3mA 2 0.7602 100 0.246 Contact Map
2o20A 2 0.7778 100 0.25 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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