GREMLIN Database
ETK - Tyrosine-protein kinase etk
UniProt: P38134 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG11826
Length: 726 (683)
Sequences: 1625 (1269)
Seq/√Len: 48.5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
610_D641_Y8.6681.00
327_E331_S6.0741.00
236_G242_I5.7671.00
472_M702_G5.6141.00
564_L637_A5.2461.00
596_E599_K4.6751.00
598_N640_H4.5841.00
247_N413_A4.5561.00
105_A207_E4.4131.00
232_L246_L4.3651.00
600_V612_I4.0511.00
533_I634_L4.0281.00
590_Y600_V3.8791.00
470_I548_V3.5731.00
634_L646_V3.5201.00
392_R395_E3.4701.00
45_A431_G3.3971.00
319_Q322_E3.2901.00
60_T250_A3.2601.00
327_E330_I3.2591.00
175_M178_Q3.2221.00
100_L245_I3.0971.00
158_G164_T3.0971.00
568_A646_V3.0701.00
321_N325_F3.0451.00
106_E248_S3.0081.00
568_A587_L2.9781.00
333_L339_P2.9671.00
323_L327_E2.9591.00
307_K311_E2.9421.00
566_I633_L2.9261.00
141_M153_L2.8801.00
520_T655_S2.8751.00
612_I633_L2.8231.00
48_Y52_S2.8041.00
159_E162_H2.7341.00
535_M648_T2.7321.00
38_T436_L2.7261.00
58_A242_I2.7081.00
618_P621_P2.6661.00
589_E616_Q2.6461.00
129_T244_R2.5451.00
205_R210_A2.5311.00
255_Q259_A2.5201.00
236_G241_L2.4871.00
535_M661_G2.4741.00
104_I210_A2.4671.00
248_S251_N2.4591.00
182_K185_V2.4121.00
549_S645_I2.4001.00
570_L588_S2.3341.00
321_N324_T2.3141.00
331_S341_Y2.2611.00
602_Q613_T2.2571.00
603_H610_D2.2461.00
566_I646_V2.2331.00
156_T199_Q2.2071.00
557_A609_F2.2051.00
19_D22_R2.1961.00
590_Y612_I2.1411.00
564_L641_Y2.1331.00
459_L681_V2.1241.00
348_R355_R2.1241.00
327_E345_L2.1201.00
220_V230_L2.1141.00
41_F438_I2.1041.00
532_N638_N2.0981.00
37_V41_F2.0911.00
468_A518_L2.0851.00
162_H173_N2.0811.00
334_Y339_P2.0751.00
597_L601_I2.0731.00
570_L649_P2.0561.00
320_L325_F2.0521.00
533_I638_N2.0521.00
57_Q233_T2.0421.00
334_Y338_H2.0241.00
158_G162_H2.0211.00
155_L189_I2.0201.00
51_L121_V1.9900.99
636_W640_H1.9840.99
75_G78_D1.9800.99
336_K339_P1.9760.99
519_R623_E1.9710.99
206_T210_A1.9610.99
89_P228_G1.9500.99
90_E253_Y1.9310.99
92_Q229_M1.9310.99
348_R354_E1.9200.99
335_K339_P1.9100.99
34_I440_V1.8740.99
581_V611_V1.8650.99
590_Y597_L1.8600.99
134_G200_F1.8270.99
291_N370_Q1.8230.99
383_R387_L1.8200.99
556_I643_L1.8140.99
214_L234_M1.8000.99
156_T164_T1.7940.99
595_D600_V1.7910.99
341_Y345_L1.7850.99
207_E211_I1.7850.99
327_E332_Q1.7810.99
556_I645_I1.7710.99
637_A644_V1.7650.99
42_T432_F1.7620.99
46_V428_V1.7510.99
164_T173_N1.7460.99
628_D632_Q1.7090.98
286_A382_G1.6960.98
216_E418_Q1.6780.98
294_R369_Q1.6730.98
49_S428_V1.6670.98
315_N318_N1.6670.98
304_L307_K1.6590.98
98_M411_D1.6460.98
535_M660_V1.6450.98
564_L644_V1.6350.98
630_M660_V1.6300.98
320_L324_T1.6160.98
320_L327_E1.6070.98
55_I237_D1.6060.98
335_K341_Y1.6020.97
101_G105_A1.6000.97
590_Y633_L1.5970.97
471_P514_A1.5940.97
62_V94_L1.5900.97
121_V125_W1.5880.97
163_Y180_L1.5840.97
248_S252_N1.5630.97
450_R454_E1.5600.97
51_L123_R1.5540.97
127_R241_L1.5490.97
538_G543_S1.5470.97
635_E639_D1.5430.97
339_P355_R1.5410.97
634_L663_S1.5390.97
470_I518_L1.5280.97
348_R352_E1.5250.97
45_A49_S1.5140.96
560_D607_G1.5140.96
320_L326_R1.5130.96
380_E384_A1.5110.96
603_H641_Y1.5080.96
597_L612_I1.5060.96
320_L348_R1.5050.96
303_N369_Q1.5040.96
102_K106_E1.4970.96
638_N665_G1.4970.96
329_E332_Q1.4910.96
92_Q223_R1.4870.96
106_E252_N1.4850.96
320_L329_E1.4820.96
629_R632_Q1.4530.95
630_M634_L1.4520.95
62_V250_A1.4510.95
49_S427_N1.4390.95
324_T327_E1.4380.95
633_L637_A1.4260.95
174_G180_L1.4220.95
154_T199_Q1.4170.95
327_E348_R1.4150.95
293_Y372_V1.4110.95
579_F609_F1.4050.95
537_T688_L1.4000.94
716_N721_S1.3940.94
668_L699_I1.3760.94
655_S659_V1.3740.94
532_N644_V1.3690.94
612_I637_A1.3670.94
632_Q636_W1.3670.94
631_R662_R1.3590.94
438_I442_A1.3570.93
333_L337_D1.3550.93
45_A427_N1.3510.93
327_E341_Y1.3500.93
325_F329_E1.3490.93
566_I644_V1.3450.93
321_N329_E1.3360.93
539_A543_S1.3360.93
535_M657_A1.3360.93
157_V176_V1.3340.93
162_H175_M1.3280.93
50_L121_V1.3270.93
712_S716_N1.3240.93
110_R204_Q1.3210.93
291_N295_Q1.3190.92
65_E260_R1.3110.92
235_T421_K1.3100.92
462_H698_A1.3090.92
553_A565_F1.3080.92
27_L440_V1.3020.92
158_G173_N1.3010.92
380_E383_R1.3010.92
46_V50_L1.3000.92
33_F37_V1.2930.92
604_F609_F1.2890.92
313_I362_V1.2870.92
217_T234_M1.2810.91
270_E274_R1.2760.91
50_L123_R1.2740.91
669_L684_S1.2690.91
92_Q95_Q1.2610.91
370_Q374_R1.2600.91
664_V667_S1.2560.91
119_P122_G1.2550.90
631_R635_E1.2540.90
631_R663_S1.2420.90
163_Y177_G1.2370.90
671_A681_V1.2350.90
628_D631_R1.2350.90
269_L396_L1.2330.90
273_Q393_Q1.2270.89
591_L624_L1.2230.89
41_F431_G1.2210.89
163_Y176_V1.2180.89
234_M245_I1.2160.89
651_M658_A1.2160.89
48_Y427_N1.2150.89
633_L644_V1.2150.89
597_L637_A1.2130.89
104_I109_L1.2120.89
100_L103_T1.2110.89
327_E339_P1.2050.89
635_E638_N1.2020.88
351_L354_E1.2000.88
566_I587_L1.1990.88
352_E355_R1.1980.88
47_A51_L1.1950.88
266_S270_E1.1940.88
549_S565_F1.1900.88
520_T659_V1.1830.88
423_K426_L1.1800.88
28_W31_R1.1780.87
57_Q235_T1.1780.87
326_R329_E1.1760.87
60_T246_L1.1730.87
18_I23_L1.1730.87
26_E447_A1.1680.87
266_S400_K1.1650.87
214_L236_G1.1640.87
321_N327_E1.1640.87
212_N215_Q1.1580.87
240_Q243_T1.1540.86
178_Q296_Q1.1520.86
333_L336_K1.1460.86
328_A331_S1.1430.86
564_L601_I1.1420.86
155_L202_L1.1390.86
716_N720_Y1.1390.86
388_Q395_E1.1370.86
334_Y337_D1.1360.85
137_A190_A1.1350.85
501_F550_S1.1320.85
116_K199_Q1.1280.85
293_Y297_R1.1280.85
103_T252_N1.1270.85
438_I441_G1.1190.85
323_L331_S1.1190.85
76_L79_M1.1180.85
320_L351_L1.1170.84
50_L428_V1.1040.84
63_Q89_P1.1030.84
24_V28_W1.1020.84
263_A267_Q1.0990.84
543_S573_G1.0970.83
58_A415_T1.0890.83
223_R231_E1.0820.83
243_T415_T1.0800.82
518_L699_I1.0680.82
240_Q244_R1.0670.82
179_R188_T1.0660.82
565_F611_V1.0650.82
372_V376_S1.0640.81
568_A630_M1.0610.81
623_E654_V1.0610.81
503_A512_V1.0600.81
533_I664_V1.0580.81
341_Y348_R1.0570.81
371_E374_R1.0570.81
241_L245_I1.0540.81
337_D342_R1.0510.81
466_V700_L1.0490.81
101_G211_I1.0460.80
220_V599_K1.0450.80
345_L348_R1.0420.80
97_R411_D1.0410.80
379_V394_Q1.0390.80
378_D382_G1.0390.80
505_D702_G1.0380.80
38_T435_G1.0350.80
213_A217_T1.0340.80
100_L104_I1.0340.80
550_S611_V1.0320.79
99_I249_I1.0310.79
102_K252_N1.0310.79
333_L338_H1.0310.79
606_K609_F1.0310.79
41_F434_L1.0270.79
282_E382_G1.0270.79
283_L379_V1.0260.79
341_Y344_L1.0230.79
305_E310_L1.0220.79
109_L245_I1.0190.79
509_D512_V1.0180.79
153_L534_L1.0110.78
601_I641_Y1.0090.78
590_Y629_R1.0080.78
430_L434_L1.0070.78
531_N665_G1.0050.78
517_A655_S1.0040.78
336_K341_Y1.0040.78
272_L393_Q1.0010.77
592_A619_P1.0010.77
661_G693_V1.0010.77
567_D573_G0.9990.77
30_H443_V0.9930.77
117_Y123_R0.9920.77
161_G175_M0.9920.77
581_V602_Q0.9900.77
99_I410_I0.9870.76
172_V180_L0.9860.76
292_V296_Q0.9860.76
49_S431_G0.9850.76
267_Q270_E0.9810.76
434_L441_G0.9810.76
537_T667_S0.9810.76
597_L640_H0.9800.76
462_H678_A0.9790.76
570_L655_S0.9780.76
539_A676_N0.9780.76
224_S227_S0.9740.75
275_Q394_Q0.9730.75
601_I637_A0.9710.75
547_F551_T0.9700.75
553_A566_I0.9670.75
413_A509_D0.9650.75
349_Q562_K0.9640.75
325_F332_Q0.9620.74
716_N719_G0.9610.74
118_F127_R0.9610.74
623_E626_M0.9600.74
598_N636_W0.9600.74
584_E602_Q0.9600.74
181_E186_A0.9580.74
667_S695_I0.9560.74
102_K105_A0.9540.74
546_T641_Y0.9530.74
470_I511_A0.9470.73
460_E686_Q0.9450.73
641_Y644_V0.9430.73
225_K253_Y0.9410.73
157_V192_I0.9390.73
60_T232_L0.9390.73
179_R182_K0.9380.73
568_A660_V0.9360.72
637_A640_H0.9340.72
668_L697_G0.9340.72
467_Y668_L0.9330.72
217_T236_G0.9300.72
318_N321_N0.9290.72
287_E294_R0.9250.71
282_E317_D0.9240.71
325_F330_I0.9230.71
92_Q224_S0.9230.71
53_T237_D0.9160.71
524_F619_P0.9150.71
271_F283_L0.9150.71
456_P459_L0.9140.71
106_E255_Q0.9140.71
212_N216_E0.9130.70
17_E20_L0.9120.70
565_F575_S0.9090.70
438_I660_V0.9070.70
158_G161_G0.9060.70
21_L25_G0.9060.70
152_Q203_S0.9050.70
61_L229_M0.9050.70
166_E169_E0.9050.70
590_Y595_D0.9040.70
138_I150_D0.9030.70
632_Q635_E0.8970.69
339_P346_E0.8950.69
588_S621_P0.8940.69
583_N616_Q0.8940.69
350_T354_E0.8930.69
685_M689_E0.8920.69
49_S424_K0.8890.68
243_T247_N0.8890.68
550_S578_L0.8880.68
97_R211_I0.8830.68
470_I515_V0.8790.68
519_R626_M0.8790.68
636_W639_D0.8720.67
255_Q258_I0.8710.67
163_Y174_G0.8700.67
208_L212_N0.8690.67
548_V670_V0.8630.66
672_R702_G0.8620.66
522_L553_A0.8580.66
526_M666_T0.8560.65
410_I524_F0.8550.65
710_A714_G0.8540.65
34_I38_T0.8520.65
541_P574_Y0.8510.65
138_I202_L0.8460.65
379_V382_G0.8460.65
386_Y390_L0.8440.64
62_V313_I0.8440.64
593_G629_R0.8430.64
180_L185_V0.8360.64
214_L245_I0.8360.64
458_Q461_E0.8360.64
128_L132_K0.8350.64
673_F707_A0.8350.64
567_D657_A0.8320.63
242_I294_R0.8310.63
421_K424_K0.8310.63
516_R623_E0.8310.63
339_P345_L0.8280.63
324_T352_E0.8270.63
265_D575_S0.8270.63
641_Y699_I0.8260.63
267_Q298_D0.8250.63
333_L355_R0.8240.63
278_E293_Y0.8230.62
620_N654_V0.8210.62
453_V678_A0.8200.62
429_V433_I0.8200.62
323_L326_R0.8190.62
37_V439_S0.8190.62
49_S52_S0.8180.62
206_T209_E0.8160.62
103_T324_T0.8140.62
444_L448_M0.8140.62
199_Q234_M0.8140.62
501_F580_T0.8130.61
155_L194_A0.8120.61
460_E466_V0.8120.61
165_L174_G0.8100.61
311_E315_N0.8090.61
261_Q380_E0.8090.61
520_T524_F0.8090.61
39_A156_T0.8080.61
465_S698_A0.8070.61
319_Q326_R0.8050.61
541_P652_L0.8030.61
322_E326_R0.8030.61
601_I610_D0.8000.60
473_S651_M0.7990.60
456_P469_T0.7990.60
323_L347_K0.7950.60
598_N601_I0.7950.60
516_R654_V0.7940.60
568_A652_L0.7940.60
439_S443_V0.7940.60
294_R400_K0.7940.60
587_L633_L0.7930.60
239_P293_Y0.7930.60
714_G720_Y0.7920.59
124_G128_L0.7900.59
597_L633_L0.7900.59
204_Q573_G0.7890.59
339_P354_E0.7870.59
282_E458_Q0.7870.59
100_L215_Q0.7840.59
220_V246_L0.7840.59
339_P342_R0.7830.59
32_K36_S0.7830.59
563_V608_G0.7820.58
52_S427_N0.7810.58
328_A582_S0.7810.58
323_L332_Q0.7780.58
286_A375_L0.7770.58
63_Q408_R0.7750.58
651_M688_L0.7740.58
20_L153_L0.7740.58
401_S591_L0.7740.58
437_F441_G0.7720.57
473_S509_D0.7720.57
565_F609_F0.7720.57
305_E460_E0.7700.57
550_S575_S0.7700.57
295_Q367_S0.7690.57
564_L612_I0.7680.57
514_A524_F0.7670.57
260_R275_Q0.7640.57
13_T40_L0.7630.57
649_P657_A0.7630.57
586_G615_G0.7620.56
321_N332_Q0.7570.56
35_I689_E0.7570.56
241_L358_L0.7570.56
570_L590_Y0.7570.56
717_Y720_Y0.7560.56
573_G653_A0.7560.56
382_G393_Q0.7560.56
525_A697_G0.7550.56
98_M365_M0.7550.56
301_D304_L0.7520.55
455_A700_L0.7510.55
423_K427_N0.7480.55
587_L630_M0.7480.55
570_L708_S0.7470.55
64_V470_I0.7450.55
392_R399_S0.7450.55
236_G294_R0.7430.55
42_T438_I0.7420.54
57_Q420_V0.7420.54
433_I599_K0.7420.54
275_Q382_G0.7410.54
550_S577_N0.7410.54
299_S372_V0.7410.54
275_Q387_L0.7400.54
354_E357_R0.7400.54
618_P654_V0.7390.54
262_A403_A0.7380.54
343_A346_E0.7370.54
715_Y720_Y0.7370.54
51_L125_W0.7350.54
33_F442_A0.7350.54
718_Y721_S0.7320.53
376_S392_R0.7310.53
236_G245_I0.7300.53
30_H446_R0.7290.53
546_T610_D0.7290.53
104_I199_Q0.7280.53
214_L410_I0.7280.53
371_E644_V0.7280.53
405_G408_R0.7270.53
339_P343_A0.7270.53
116_K201_V0.7230.53
545_K647_D0.7230.53
597_L636_W0.7200.52
411_D625_L0.7190.52
395_E403_A0.7190.52
159_E196_P0.7190.52
178_Q188_T0.7190.52
617_V633_L0.7170.52
117_Y124_G0.7170.52
712_S719_G0.7170.52
641_Y670_V0.7160.52
31_R268_S0.7160.52
58_A236_G0.7150.52
330_I339_P0.7150.52
36_S39_A0.7140.52
681_V685_M0.7130.52
31_R35_I0.7120.51
565_F645_I0.7100.51
65_E257_N0.7100.51
293_Y501_F0.7070.51
138_I441_G0.7070.51
518_L668_L0.7060.51
221_S231_E0.7030.51
66_Q219_T0.7020.50
220_V234_M0.7000.50
63_Q93_L0.7000.50
472_M704_I0.6980.50
111_D682_S0.6980.50
104_I207_E0.6960.50
164_T170_F0.6960.50
534_L686_Q0.6960.50
321_N326_R0.6950.50
253_Y422_P0.6940.50
337_D340_T0.6930.50
27_L34_I0.6920.49
164_T424_K0.6910.49
556_I699_I0.6910.49
388_Q392_R0.6900.49
102_K256_Q0.6900.49
305_E625_L0.6890.49
39_A566_I0.6890.49
95_Q667_S0.6860.49
559_S626_M0.6860.49
244_R247_N0.6860.49
537_T602_Q0.6850.49
441_G445_A0.6850.49
260_R408_R0.6840.49
570_L618_P0.6830.49
42_T428_V0.6820.48
419_P424_K0.6820.48
552_L648_T0.6810.48
88_A93_L0.6800.48
167_G170_F0.6800.48
453_V537_T0.6790.48
95_Q430_L0.6790.48
292_V297_R0.6790.48
585_H595_D0.6760.48
540_T676_N0.6740.48
326_R347_K0.6740.48
106_E453_V0.6730.48
100_L211_I0.6730.48
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23_L445_A0.6720.47
117_Y126_A0.6720.47
177_G190_A0.6710.47
539_A669_L0.6710.47
331_S345_L0.6700.47
465_S637_A0.6670.47
247_N251_N0.6670.47
509_D573_G0.6670.47
569_D650_P0.6660.47
524_F651_M0.6660.47
638_N644_V0.6640.47
258_I262_A0.6630.47
550_S579_F0.6610.46
75_G79_M0.6600.46
103_T248_S0.6590.46
97_R414_V0.6580.46
323_L329_E0.6580.46
396_L555_V0.6580.46
621_P654_V0.6570.46
262_A362_V0.6550.46
204_Q210_A0.6550.46
324_T329_E0.6540.46
593_G618_P0.6540.46
561_Q590_Y0.6530.46
342_R345_L0.6530.46
287_E377_R0.6520.45
588_S619_P0.6520.45
324_T331_S0.6500.45
505_D699_I0.6500.45
128_L591_L0.6490.45
461_E614_R0.6490.45
367_S371_E0.6490.45
465_S672_R0.6490.45
393_Q397_S0.6480.45
601_I640_H0.6480.45
352_E409_I0.6480.45
235_T420_V0.6470.45
410_I549_S0.6460.45
300_V655_S0.6450.45
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595_D599_K0.6440.45
459_L698_A0.6440.45
402_S405_G0.6430.45
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153_L202_L0.6430.45
525_A632_Q0.6420.44
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511_A514_A0.6410.44
334_Y341_Y0.6410.44
82_N669_L0.6410.44
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275_Q458_Q0.6400.44
170_F173_N0.6400.44
575_S578_L0.6400.44
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45_A218_F0.6400.44
326_R330_I0.6390.44
546_T647_D0.6390.44
513_E571_R0.6380.44
618_P622_S0.6380.44
570_L593_G0.6380.44
130_K315_N0.6360.44
156_T166_E0.6360.44
426_L430_L0.6350.44
261_Q362_V0.6350.44
241_L244_R0.6340.44
452_G538_G0.6330.44
512_V682_S0.6330.44
424_K428_V0.6330.44
337_D341_Y0.6310.43
262_A267_Q0.6310.43
20_L52_S0.6300.43
289_K375_L0.6290.43
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338_H345_L0.6170.42
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571_R621_P0.6110.41
613_T618_P0.6100.41
567_D617_V0.6100.41
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372_V391_N0.6100.41
535_M646_V0.6090.41
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413_A419_P0.5990.40
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538_G545_K0.5950.40
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714_G721_S0.5940.40
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358_L718_Y0.5930.40
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652_L697_G0.5900.39
51_L124_G0.5900.39
353_Q360_K0.5900.39
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157_V196_P0.5630.37
376_S458_Q0.5630.37
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343_A355_R0.5620.37
40_L44_I0.5620.37
632_Q699_I0.5610.37
709_T716_N0.5610.37
24_V549_S0.5600.36
334_Y355_R0.5600.36
384_A391_N0.5600.36
717_Y721_S0.5600.36
170_F719_G0.5590.36
519_R571_R0.5590.36
471_P567_D0.5580.36
564_L610_D0.5580.36
543_S702_G0.5570.36
202_L397_S0.5570.36
276_L681_V0.5570.36
268_S385_V0.5570.36
435_G439_S0.5570.36
343_A350_T0.5550.36
536_I668_L0.5550.36
446_R589_E0.5550.36
471_P541_P0.5540.36
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275_Q397_S0.5530.36
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535_M667_S0.5520.36
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30_H668_L0.5510.36
295_Q348_R0.5510.36
341_Y355_R0.5510.36
236_G293_Y0.5510.36
557_A560_D0.5500.36
242_I415_T0.5500.36
254_L382_G0.5490.35
517_A579_F0.5490.35
74_S85_P0.5480.35
156_T234_M0.5480.35
67_K261_Q0.5480.35
44_I418_Q0.5480.35
35_I156_T0.5470.35
351_L355_R0.5470.35
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542_D603_H0.5420.35
714_G719_G0.5420.35
292_V295_Q0.5410.35
216_E219_T0.5410.35
29_D451_R0.5410.35
183_D438_I0.5400.35
105_A634_L0.5400.35
600_V629_R0.5400.35
181_E438_I0.5400.35
430_L437_F0.5400.35
330_I358_L0.5390.35
304_L308_A0.5390.35
708_S712_S0.5390.35
464_I529_T0.5390.35
141_M202_L0.5390.35
26_E30_H0.5390.35
342_R346_E0.5380.34
384_A560_D0.5380.34
397_S400_K0.5380.34
385_V390_L0.5380.34
562_K705_K0.5380.34
449_L570_L0.5380.34
383_R514_A0.5380.34
32_K561_Q0.5370.34
444_L660_V0.5370.34
667_S693_V0.5370.34
571_R654_V0.5370.34
621_P624_L0.5370.34
285_Q289_K0.5360.34
156_T197_G0.5360.34
109_L234_M0.5360.34
691_A699_I0.5360.34
257_N339_P0.5360.34
299_S557_A0.5360.34
103_T588_S0.5360.34
257_N407_V0.5350.34
318_N325_F0.5350.34
168_E418_Q0.5350.34
160_N342_R0.5350.34
94_L218_F0.5350.34
338_H341_Y0.5350.34
65_E228_G0.5350.34
148_G153_L0.5340.34
680_E697_G0.5340.34
574_Y577_N0.5330.34
287_E306_A0.5320.34
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375_L439_S0.5300.34
259_A470_I0.5300.34
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558_Q652_L0.5290.34
294_R323_L0.5280.34
556_I570_L0.5280.34
544_G647_D0.5280.34
118_F348_R0.5260.33
457_E700_L0.5260.33
139_S219_T0.5260.33
42_T218_F0.5260.33
83_S241_L0.5250.33
545_K571_R0.5250.33
540_T653_A0.5250.33
67_K433_I0.5250.33
360_K363_S0.5250.33
364_A612_I0.5240.33
218_F234_M0.5230.33
341_Y383_R0.5230.33
105_A110_R0.5230.33
671_A698_A0.5230.33
645_I699_I0.5220.33
43_L169_E0.5220.33
570_L663_S0.5220.33
318_N323_L0.5210.33
221_S440_V0.5210.33
36_S220_V0.5210.33
220_V441_G0.5210.33
27_L649_P0.5210.33
537_T657_A0.5200.33
157_V160_N0.5200.33
655_S660_V0.5200.33
209_E418_Q0.5200.33
18_I426_L0.5190.33
290_L652_L0.5190.33
202_L455_A0.5190.33
294_R305_E0.5180.33
309_V579_F0.5180.33
282_E286_A0.5180.33
95_Q232_L0.5180.33
614_R617_V0.5170.33
39_A68_Q0.5170.33
622_S655_S0.5170.33
310_L314_V0.5170.33
450_R681_V0.5170.33
273_Q686_Q0.5170.33
167_G441_G0.5160.32
713_Y717_Y0.5160.32
59_D231_E0.5160.32
118_F125_W0.5150.32
453_V681_V0.5150.32
154_T639_D0.5140.32
72_I265_D0.5140.32
230_L581_V0.5140.32
169_E173_N0.5140.32
272_L525_A0.5140.32
221_S425_A0.5130.32
316_V320_L0.5130.32
326_R333_L0.5130.32
583_N614_R0.5130.32
35_I596_E0.5130.32
156_T205_R0.5120.32
176_V217_T0.5120.32
223_R580_T0.5120.32
674_G704_I0.5110.32
456_P460_E0.5110.32
571_R656_D0.5110.32
234_M514_A0.5110.32
528_E631_R0.5100.32
545_K650_P0.5100.32
35_I644_V0.5100.32
118_F121_V0.5100.32
255_Q296_Q0.5100.32
432_F437_F0.5090.32
140_W186_A0.5090.32
513_E569_D0.5090.32
646_V693_V0.5090.32
55_I420_V0.5080.32
560_D612_I0.5080.32
373_L541_P0.5080.32
94_L361_R0.5080.32
36_S682_S0.5070.32
25_G28_W0.5070.32
189_I655_S0.5070.32
123_R126_A0.5070.32
189_I192_I0.5070.32
327_E335_K0.5060.32
570_L651_M0.5060.32
133_P187_L0.5060.32
450_R470_I0.5050.31
225_K438_I0.5050.31
43_L173_N0.5050.31
89_P264_Q0.5050.31
162_H445_A0.5050.31
300_V306_A0.5040.31
142_H186_A0.5040.31
229_M520_T0.5040.31
513_E654_V0.5040.31
519_R622_S0.5030.31
459_L479_R0.5030.31
230_L549_S0.5020.31
370_Q382_G0.5020.31
230_L245_I0.5020.31
244_R542_D0.5010.31
587_L591_L0.5010.31
346_E355_R0.5000.31
465_S702_G0.5000.31
629_R633_L0.5000.31
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3cioA 2 0.3554 100 0.677 Contact Map
3la6A 4 0.3623 100 0.69 Contact Map
4jlvA 1 0.3127 100 0.712 Contact Map
4jmpA 1 0.3099 100 0.717 Contact Map
4wl1A 3 0.3003 100 0.825 Contact Map
4rz3A 2 0.2686 100 0.84 Contact Map
3fkqA 2 0.4187 100 0.844 Contact Map
3ug7A 4 0.2865 100 0.847 Contact Map
1g3qA 1 0.2686 100 0.851 Contact Map
1hyqA 1 0.2658 100 0.855 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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