CYSJ - ECOLI - GREMLIN Contacts

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CYSJ - Sulfite reductase [NADPH] flavoprotein alpha-component

UniProt:	P38038	Sequences: MTTQVPPSALLPLNPEQLARLQAATTDLTPTQLAWVSGYFWGVLNQQPAALAATPAPAAEMPGITIISASQTGNARRVAEALRDDLLAAKLNVKLVNAGDYKFKQIASEKLLIVVTSTQGEGEPPEEAVALHKFLFSKKAPKLENTAFAVFSLGDSSYEFFCQSGKDFDSKLAELGGERLLDRVDADVEYQAAASEWRARVVDALKSRAPVAAPSQSVATGAVNEIHTSPYSKDAPLVASLSVNQKITGRNSEKDVRHIEIDLGDSGMRYQPGDALGVWYQNDPALVKELVELLWLKGDEPVTVEGKTLPLNEALQWHFELTVNTANIVENYATLTRSETLLPLVGDKAKLQHYAATTPIVDMVRFSPAQLDAEALINLLRPLTPRLYSIASSQAEVENEVHVTVGVVRYDVEGRARAGGASSFLADRVEEEGEVRVFIEHNDNFRLPANPETPVIMIGPGTGIAPFRAFMQQRAADEAPGKNWLFFGNPHFTEDFLYQVEWQRYVKDGVLTRIDLAWSRDQKEKVYVQDKLREQGAELWRWINDGAHIYVCGDANRMAKDVEQALLEVIAEFGGMDTEAADEFLSELRVERRYQRDVY	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG10191
Length:	599 (533)
Sequences:	2647 (1811)
Seq/√Len:	78.4

ECOLI - CYSJ
BACSU - CYSJ CYPD CYPE

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
458_I	549_I	5.533	1.00
152_S	165_G	4.467	1.00
536_G	573_F	4.413	1.00
169_D	179_R	4.404	1.00
533_R	568_E	4.205	1.00
532_L	539_L	4.065	1.00
532_L	569_V	3.972	1.00
71_Q	126_E	3.730	1.00
577_D	580_A	3.655	1.00
244_N	257_R	3.417	1.00
171_K	174_E	3.264	1.00
587_E	591_E	3.214	1.00
542_W	547_A	3.210	1.00
391_A	404_T	3.205	1.00
291_V	298_G	3.076	1.00
499_Q	503_Q	3.075	1.00
541_R	545_D	3.064	1.00
101_Y	109_E	2.992	1.00
173_A	179_R	2.984	1.00
147_A	178_E	2.983	1.00
171_K	175_L	2.954	1.00
531_K	534_E	2.895	1.00
551_V	594_Y	2.846	1.00
515_D	535_Q	2.836	1.00
492_F	521_D	2.807	1.00
571_A	578_T	2.778	1.00
166_K	185_D	2.676	1.00
64_I	86_L	2.640	1.00
288_K	312_N	2.625	1.00
409_R	416_A	2.621	1.00
113_I	201_V	2.497	1.00
289_E	365_R	2.494	1.00
151_F	186_A	2.460	1.00
246_K	255_D	2.380	1.00
530_D	533_R	2.380	1.00
239_A	437_V	2.356	1.00
502_W	514_I	2.355	1.00
277_G	387_L	2.329	1.00
148_F	173_A	2.324	1.00
83_R	95_L	2.303	1.00
536_G	572_E	2.300	1.00
70_S	127_E	2.268	1.00
277_G	438_F	2.251	1.00
496_F	518_W	2.243	1.00
541_R	544_N	2.187	1.00
504_R	508_D	2.161	1.00
537_A	573_F	2.151	1.00
451_P	477_D	2.130	1.00
482_K	545_D	2.116	1.00
492_F	499_Q	2.111	1.00
151_F	194_A	2.093	1.00
464_I	502_W	2.089	1.00
281_Q	317_W	2.085	1.00
383_L	420_G	2.078	1.00
163_Q	167_D	2.078	1.00
540_W	570_I	2.077	1.00
181_L	200_R	2.051	1.00
263_L	401_V	2.046	1.00
313_E	317_W	2.022	1.00
335_L	372_D	2.010	1.00
86_L	202_V	2.004	1.00
447_L	455_V	1.996	1.00
329_V	363_M	1.961	1.00
98_A	131_L	1.952	1.00
471_M	502_W	1.951	1.00
522_Q	526_V	1.940	1.00
543_I	549_I	1.939	1.00
299_D	312_N	1.921	1.00
76_R	80_E	1.907	1.00
148_F	169_D	1.881	1.00
284_P	316_Q	1.874	1.00
260_E	402_H	1.869	1.00
472_Q	501_E	1.864	1.00
261_I	435_V	1.852	1.00
67_I	98_A	1.845	1.00
69_A	128_A	1.819	1.00
312_N	316_Q	1.806	1.00
290_L	321_L	1.794	1.00
533_R	536_G	1.780	1.00
520_R	527_Y	1.775	1.00
351_L	355_A	1.764	1.00
486_F	535_Q	1.756	1.00
82_L	198_R	1.755	1.00
288_K	292_E	1.753	1.00
404_T	498_Y	1.723	1.00
276_L	437_V	1.721	1.00
473_Q	477_D	1.705	1.00
486_F	515_D	1.701	1.00
474_R	481_G	1.701	1.00
430_E	433_G	1.696	1.00
148_F	177_G	1.681	1.00
549_I	566_L	1.665	1.00
540_W	574_G	1.657	1.00
457_M	467_F	1.639	1.00
170_S	174_E	1.632	1.00
515_D	538_E	1.614	1.00
69_A	116_T	1.612	1.00
239_A	261_I	1.602	1.00
372_D	375_A	1.595	1.00
397_V	472_Q	1.595	1.00
533_R	565_A	1.578	1.00
148_F	179_R	1.575	1.00
418_A	423_S	1.565	0.99
397_V	402_H	1.561	0.99
475_A	508_D	1.560	0.99
253_E	490_P	1.557	0.99
114_V	168_F	1.548	0.99
491_H	494_E	1.537	0.99
429_V	433_G	1.536	0.99
333_A	342_L	1.512	0.99
147_A	208_R	1.511	0.99
535_Q	538_E	1.504	0.99
395_A	473_Q	1.495	0.99
558_M	562_V	1.491	0.99
70_S	75_A	1.490	0.99
460_P	467_F	1.487	0.99
475_A	505_Y	1.480	0.99
570_I	585_L	1.477	0.99
513_R	535_Q	1.477	0.99
238_V	434_E	1.466	0.99
78_V	194_A	1.457	0.99
496_F	516_L	1.454	0.99
484_W	515_D	1.443	0.99
258_H	402_H	1.442	0.99
347_D	350_K	1.437	0.99
117_S	125_P	1.436	0.99
248_T	256_V	1.436	0.99
424_F	436_R	1.432	0.99
319_F	377_I	1.416	0.99
124_P	164_S	1.414	0.99
554_D	559_A	1.411	0.99
513_R	538_E	1.410	0.99
143_L	177_G	1.408	0.99
567_L	582_D	1.395	0.99
297_K	300_E	1.390	0.99
335_L	375_A	1.379	0.99
251_N	494_E	1.378	0.99
338_S	342_L	1.367	0.99
455_V	483_N	1.362	0.99
564_Q	567_L	1.359	0.99
568_E	571_A	1.357	0.99
559_A	598_V	1.347	0.98
457_M	483_N	1.346	0.98
283_D	418_A	1.345	0.98
69_A	98_A	1.343	0.98
66_I	83_R	1.342	0.98
261_I	437_V	1.341	0.98
82_L	115_V	1.338	0.98
298_G	312_N	1.335	0.98
169_D	173_A	1.335	0.98
570_I	576_M	1.333	0.98
537_A	541_R	1.332	0.98
258_H	498_Y	1.329	0.98
526_V	531_K	1.322	0.98
456_I	539_L	1.322	0.98
468_R	501_E	1.320	0.98
496_F	503_Q	1.313	0.98
132_H	167_D	1.302	0.98
113_I	149_A	1.298	0.98
240_S	432_E	1.287	0.98
82_L	113_I	1.284	0.98
270_Y	392_S	1.281	0.98
150_V	165_G	1.278	0.98
563_E	585_L	1.273	0.98
315_L	373_A	1.265	0.98
149_A	180_L	1.261	0.98
549_I	588_L	1.261	0.98
485_L	511_L	1.256	0.98
539_L	543_I	1.256	0.98
486_F	539_L	1.255	0.98
315_L	319_F	1.248	0.97
132_H	168_F	1.242	0.97
112_L	146_T	1.241	0.97
237_L	266_S	1.239	0.97
580_A	583_E	1.236	0.97
565_A	569_V	1.235	0.97
484_W	539_L	1.235	0.97
407_V	423_S	1.231	0.97
515_D	531_K	1.229	0.97
456_I	547_A	1.225	0.97
162_C	165_G	1.215	0.97
503_Q	507_K	1.212	0.97
114_V	172_L	1.212	0.97
524_E	530_D	1.208	0.97
458_I	566_L	1.207	0.97
407_V	422_S	1.204	0.97
340_T	366_F	1.199	0.97
116_T	168_F	1.199	0.97
149_A	181_L	1.196	0.97
563_E	596_R	1.189	0.97
243_V	260_E	1.188	0.97
162_C	185_D	1.187	0.97
149_A	201_V	1.186	0.96
570_I	584_F	1.184	0.96
351_L	356_A	1.182	0.96
146_T	172_L	1.182	0.96
276_L	401_V	1.180	0.96
391_A	498_Y	1.178	0.96
65_T	112_L	1.176	0.96
241_L	244_N	1.173	0.96
242_S	400_E	1.173	0.96
287_V	316_Q	1.169	0.96
275_A	387_L	1.151	0.96
204_A	207_S	1.140	0.96
163_Q	166_K	1.137	0.96
393_S	473_Q	1.132	0.95
111_L	205_L	1.132	0.95
78_V	115_V	1.129	0.95
170_S	173_A	1.123	0.95
290_L	294_L	1.123	0.95
564_Q	578_T	1.121	0.95
152_S	162_C	1.119	0.95
74_N	117_S	1.117	0.95
262_D	400_E	1.114	0.95
405_V	422_S	1.112	0.95
570_I	588_L	1.111	0.95
290_L	315_L	1.110	0.95
578_T	582_D	1.110	0.95
201_V	205_L	1.110	0.95
467_F	470_F	1.101	0.95
260_E	400_E	1.101	0.95
289_E	293_L	1.095	0.95
460_P	558_M	1.094	0.94
340_T	343_P	1.090	0.94
232_S	236_P	1.090	0.94
231_Y	236_P	1.090	0.94
350_K	353_H	1.085	0.94
271_Q	441_H	1.083	0.94
567_L	578_T	1.081	0.94
354_Y	358_T	1.081	0.94
238_V	436_R	1.074	0.94
471_M	505_Y	1.072	0.94
554_D	557_R	1.061	0.94
62_P	111_L	1.055	0.93
120_G	123_E	1.051	0.93
131_L	168_F	1.051	0.93
538_E	541_R	1.050	0.93
397_V	400_E	1.038	0.93
453_T	548_H	1.038	0.93
67_I	112_L	1.038	0.93
411_D	416_A	1.036	0.93
85_D	198_R	1.030	0.92
456_I	549_I	1.029	0.92
336_T	369_A	1.028	0.92
491_H	521_D	1.027	0.92
548_H	595_Q	1.026	0.92
98_A	127_E	1.024	0.92
138_K	141_P	1.023	0.92
402_H	468_R	1.019	0.92
374_E	378_N	1.017	0.92
395_A	477_D	1.014	0.92
182_D	200_R	1.011	0.92
336_T	368_P	1.010	0.92
241_L	429_V	1.010	0.92
490_P	527_Y	1.009	0.92
240_S	262_D	1.009	0.92
409_R	427_D	1.008	0.92
69_A	127_E	1.004	0.92
571_A	577_D	1.003	0.91
500_V	503_Q	1.002	0.91
186_A	194_A	0.998	0.91
111_L	147_A	0.997	0.91
99_G	127_E	0.997	0.91
272_P	394_Q	0.997	0.91
528_V	562_V	0.996	0.91
151_F	184_V	0.996	0.91
74_N	190_Y	0.996	0.91
504_R	507_K	0.995	0.91
454_P	545_D	0.990	0.91
116_T	125_P	0.989	0.91
302_V	311_L	0.988	0.91
273_G	389_S	0.981	0.91
533_R	572_E	0.978	0.90
293_L	365_R	0.978	0.90
564_Q	568_E	0.976	0.90
145_N	178_E	0.973	0.90
337_R	368_P	0.964	0.90
486_F	531_K	0.958	0.89
256_V	497_L	0.957	0.89
259_I	425_L	0.957	0.89
67_I	101_Y	0.953	0.89
109_E	112_L	0.951	0.89
446_R	469_A	0.948	0.89
249_G	252_S	0.947	0.89
460_P	554_D	0.946	0.89
549_I	584_F	0.945	0.89
482_K	513_R	0.945	0.89
387_L	440_E	0.940	0.89
555_A	559_A	0.936	0.88
237_L	265_D	0.935	0.88
409_R	418_A	0.933	0.88
529_Q	558_M	0.933	0.88
132_H	164_S	0.931	0.88
475_A	510_V	0.929	0.88
501_E	505_Y	0.928	0.88
519_S	527_Y	0.928	0.88
503_Q	506_V	0.925	0.88
286_L	322_T	0.925	0.88
576_M	580_A	0.924	0.88
172_L	177_G	0.920	0.88
540_W	584_F	0.917	0.87
263_L	266_S	0.916	0.87
567_L	581_A	0.913	0.87
570_I	574_G	0.912	0.87
496_F	514_I	0.910	0.87
78_V	153_L	0.908	0.87
293_L	364_V	0.908	0.87
118_T	162_C	0.908	0.87
328_I	360_I	0.907	0.87
582_D	586_S	0.904	0.87
544_N	576_M	0.904	0.87
579_E	582_D	0.900	0.86
563_E	589_R	0.900	0.86
290_L	364_V	0.899	0.86
150_V	169_D	0.899	0.86
271_Q	395_A	0.898	0.86
539_L	547_A	0.897	0.86
97_N	127_E	0.896	0.86
295_W	370_Q	0.894	0.86
396_E	472_Q	0.891	0.86
544_N	570_I	0.885	0.85
460_P	516_L	0.882	0.85
136_F	171_K	0.882	0.85
67_I	114_V	0.881	0.85
247_I	404_T	0.878	0.85
271_Q	446_R	0.875	0.85
561_D	565_A	0.874	0.85
390_I	401_V	0.872	0.85
288_K	316_Q	0.869	0.84
65_T	94_K	0.866	0.84
536_G	574_G	0.864	0.84
583_E	587_E	0.864	0.84
532_L	566_L	0.864	0.84
245_Q	258_H	0.862	0.84
260_E	498_Y	0.861	0.84
248_T	255_D	0.860	0.84
490_P	520_R	0.859	0.84
285_A	288_K	0.859	0.84
166_K	170_S	0.856	0.83
80_E	95_L	0.856	0.83
450_N	453_T	0.854	0.83
241_L	261_I	0.852	0.83
71_Q	75_A	0.852	0.83
75_A	115_V	0.848	0.83
476_A	480_P	0.846	0.83
447_L	470_F	0.846	0.83
118_T	165_G	0.842	0.82
121_E	159_E	0.841	0.82
96_V	100_D	0.841	0.82
527_Y	558_M	0.841	0.82
294_L	371_L	0.841	0.82
532_L	565_A	0.841	0.82
303_T	308_T	0.839	0.82
116_T	164_S	0.838	0.82
105_Q	108_S	0.838	0.82
97_N	100_D	0.835	0.82
563_E	567_L	0.834	0.82
120_G	158_Y	0.829	0.81
351_L	354_Y	0.826	0.81
241_L	259_I	0.826	0.81
472_Q	505_Y	0.826	0.81
258_H	468_R	0.826	0.81
387_L	438_F	0.826	0.81
536_G	569_V	0.825	0.81
355_A	358_T	0.822	0.81
309_L	314_A	0.821	0.81
471_M	510_V	0.816	0.80
482_K	538_E	0.815	0.80
358_T	412_V	0.815	0.80
486_F	532_L	0.813	0.80
563_E	594_Y	0.808	0.80
203_D	207_S	0.808	0.80
324_N	360_I	0.808	0.80
530_D	561_D	0.806	0.80
242_S	262_D	0.805	0.80
262_D	266_S	0.803	0.79
454_P	482_K	0.802	0.79
517_A	525_K	0.801	0.79
343_P	350_K	0.801	0.79
66_I	95_L	0.800	0.79
246_K	254_K	0.798	0.79
240_S	434_E	0.797	0.79
134_F	138_K	0.793	0.78
314_A	319_F	0.789	0.78
404_T	470_F	0.787	0.78
328_I	379_L	0.786	0.78
165_G	185_D	0.786	0.78
506_V	513_R	0.786	0.78
404_T	497_L	0.784	0.78
150_V	179_R	0.783	0.78
263_L	267_G	0.782	0.78
466_P	552_C	0.781	0.77
244_N	259_I	0.776	0.77
490_P	519_S	0.775	0.77
341_L	345_V	0.774	0.77
276_L	439_I	0.772	0.77
199_A	203_D	0.770	0.76
474_R	483_N	0.769	0.76
180_L	200_R	0.768	0.76
68_S	75_A	0.766	0.76
264_G	399_N	0.766	0.76
280_Y	420_G	0.765	0.76
464_I	485_L	0.762	0.76
278_V	437_V	0.760	0.75
551_V	596_R	0.760	0.75
196_E	200_R	0.758	0.75
76_R	127_E	0.756	0.75
543_I	547_A	0.756	0.75
304_V	319_F	0.755	0.75
471_M	483_N	0.754	0.75
309_L	318_H	0.754	0.75
540_W	573_F	0.753	0.75
550_Y	595_Q	0.750	0.75
128_A	552_C	0.749	0.74
151_F	381_R	0.748	0.74
516_L	531_K	0.746	0.74
116_T	128_A	0.745	0.74
116_T	127_E	0.745	0.74
391_A	403_V	0.743	0.74
359_P	415_R	0.739	0.73
135_L	171_K	0.738	0.73
561_D	564_Q	0.738	0.73
281_Q	424_F	0.737	0.73
539_L	569_V	0.735	0.73
529_Q	562_V	0.732	0.73
85_D	89_A	0.729	0.72
528_V	558_M	0.728	0.72
460_P	561_D	0.721	0.72
418_A	427_D	0.721	0.72
256_V	406_G	0.720	0.72
479_A	508_D	0.720	0.72
64_I	113_I	0.719	0.71
589_R	596_R	0.719	0.71
272_P	469_A	0.718	0.71
248_T	254_K	0.718	0.71
576_M	584_F	0.717	0.71
298_G	301_P	0.717	0.71
254_K	406_G	0.714	0.71
396_E	399_N	0.713	0.71
135_L	172_L	0.712	0.71
577_D	581_A	0.712	0.71
65_T	110_K	0.712	0.71
124_P	128_A	0.711	0.71
69_A	86_L	0.711	0.71
410_Y	417_R	0.709	0.70
291_V	315_L	0.707	0.70
321_L	420_G	0.706	0.70
325_T	328_I	0.705	0.70
100_D	127_E	0.705	0.70
456_I	467_F	0.703	0.70
468_R	472_Q	0.699	0.69
237_L	264_G	0.699	0.69
457_M	485_L	0.698	0.69
319_F	374_E	0.698	0.69
85_D	202_V	0.696	0.69
554_D	597_D	0.696	0.69
179_R	182_D	0.696	0.69
83_R	93_V	0.695	0.69
568_E	572_E	0.695	0.69
294_L	373_A	0.694	0.69
268_M	439_I	0.692	0.68
285_A	418_A	0.692	0.68
496_F	502_W	0.691	0.68
518_W	521_D	0.691	0.68
101_Y	134_F	0.691	0.68
99_G	130_A	0.691	0.68
471_M	475_A	0.690	0.68
249_G	494_E	0.690	0.68
149_A	152_S	0.690	0.68
557_R	561_D	0.689	0.68
484_W	538_E	0.687	0.68
530_D	557_R	0.686	0.68
243_V	431_E	0.686	0.68
297_K	310_P	0.684	0.68
275_A	559_A	0.683	0.67
343_P	346_G	0.680	0.67
350_K	354_Y	0.680	0.67
301_P	310_P	0.680	0.67
245_Q	500_V	0.679	0.67
483_N	510_V	0.678	0.67
391_A	402_H	0.676	0.67
158_Y	162_C	0.676	0.67
68_S	127_E	0.675	0.67
241_L	431_E	0.674	0.66
257_R	403_V	0.674	0.66
563_E	582_D	0.674	0.66
484_W	542_W	0.671	0.66
565_A	568_E	0.671	0.66
81_A	191_Q	0.666	0.66
311_L	373_A	0.665	0.65
77_R	81_A	0.665	0.65
120_G	153_L	0.662	0.65
160_F	163_Q	0.662	0.65
291_V	296_L	0.662	0.65
338_S	341_L	0.662	0.65
404_T	468_R	0.661	0.65
181_L	201_V	0.661	0.65
248_T	251_N	0.661	0.65
326_A	345_V	0.659	0.65
405_V	425_L	0.659	0.65
574_G	584_F	0.659	0.65
69_A	124_P	0.658	0.65
161_F	183_R	0.656	0.64
475_A	504_R	0.656	0.64
241_L	433_G	0.655	0.64
64_I	91_L	0.655	0.64
493_T	521_D	0.653	0.64
91_L	209_A	0.653	0.64
339_E	346_G	0.653	0.64
258_H	404_T	0.653	0.64
169_D	183_R	0.651	0.64
177_G	501_E	0.651	0.64
464_I	497_L	0.650	0.64
63_G	92_N	0.649	0.64
340_T	350_K	0.649	0.64
248_T	252_S	0.649	0.64
544_N	584_F	0.648	0.63
435_V	578_T	0.646	0.63
403_V	439_I	0.645	0.63
559_A	597_D	0.645	0.63
158_Y	165_G	0.644	0.63
584_F	588_L	0.644	0.63
339_E	378_N	0.644	0.63
411_D	414_G	0.643	0.63
132_H	171_K	0.641	0.63
193_A	196_E	0.637	0.62
334_T	342_L	0.637	0.62
338_S	345_V	0.636	0.62
506_V	511_L	0.634	0.62
567_L	585_L	0.633	0.62
119_Q	384_T	0.633	0.62
290_L	380_L	0.633	0.62
186_A	193_A	0.631	0.61
320_E	324_N	0.629	0.61
182_D	205_L	0.628	0.61
349_A	353_H	0.628	0.61
524_E	534_E	0.627	0.61
91_L	352_Q	0.626	0.61
296_L	311_L	0.626	0.61
233_K	236_P	0.625	0.61
135_L	276_L	0.625	0.61
330_E	334_T	0.624	0.61
270_Y	391_A	0.622	0.60
156_S	187_D	0.621	0.60
458_I	562_V	0.621	0.60
394_Q	398_E	0.620	0.60
393_S	402_H	0.619	0.60
121_E	160_F	0.618	0.60
93_V	96_V	0.618	0.60
488_G	519_S	0.617	0.60
76_R	443_D	0.616	0.60
505_Y	508_D	0.616	0.60
424_F	435_V	0.613	0.59
496_F	499_Q	0.613	0.59
337_R	340_T	0.613	0.59
183_R	284_P	0.612	0.59
514_I	518_W	0.611	0.59
56_A	205_L	0.611	0.59
78_V	188_V	0.611	0.59
324_N	329_V	0.610	0.59
347_D	351_L	0.610	0.59
588_L	593_R	0.609	0.59
66_I	86_L	0.609	0.59
118_T	164_S	0.609	0.59
310_P	329_V	0.609	0.59
161_F	272_P	0.608	0.59
320_E	366_F	0.608	0.59
517_A	526_V	0.607	0.58
290_L	376_L	0.607	0.58
155_D	275_A	0.607	0.58
236_P	239_A	0.607	0.58
331_N	371_L	0.606	0.58
456_I	466_P	0.606	0.58
143_L	496_F	0.606	0.58
276_L	403_V	0.605	0.58
374_E	377_I	0.604	0.58
236_P	438_F	0.604	0.58
362_D	417_R	0.604	0.58
127_E	332_Y	0.604	0.58
459_G	467_F	0.604	0.58
184_V	193_A	0.601	0.58
292_E	295_W	0.599	0.57
532_L	549_I	0.599	0.57
280_Y	358_T	0.599	0.57
313_E	364_V	0.598	0.57
469_A	472_Q	0.598	0.57
579_E	583_E	0.598	0.57
153_L	188_V	0.598	0.57
153_L	158_Y	0.598	0.57
525_K	531_K	0.595	0.57
324_N	359_P	0.595	0.57
291_V	295_W	0.594	0.57
98_A	168_F	0.591	0.56
59_A	223_V	0.591	0.56
364_V	369_A	0.590	0.56
181_L	184_V	0.590	0.56
108_S	145_N	0.590	0.56
253_E	491_H	0.589	0.56
458_I	539_L	0.589	0.56
89_A	206_K	0.589	0.56
184_V	197_W	0.588	0.56
109_E	115_V	0.587	0.56
341_L	354_Y	0.585	0.56
404_T	464_I	0.585	0.56
91_L	202_V	0.585	0.56
145_N	203_D	0.584	0.56
75_A	186_A	0.584	0.56
69_A	164_S	0.584	0.56
379_L	421_A	0.583	0.55
331_N	335_L	0.582	0.55
310_P	313_E	0.582	0.55
243_V	258_H	0.581	0.55
403_V	425_L	0.581	0.55
160_F	165_G	0.581	0.55
394_Q	397_V	0.579	0.55
251_N	396_E	0.579	0.55
495_D	525_K	0.579	0.55
80_E	83_R	0.579	0.55
389_S	597_D	0.577	0.55
255_D	409_R	0.577	0.55
136_F	167_D	0.575	0.54
299_D	568_E	0.575	0.54
86_L	443_D	0.575	0.54
470_F	498_Y	0.574	0.54
505_Y	510_V	0.573	0.54
539_L	566_L	0.573	0.54
489_N	516_L	0.573	0.54
277_G	440_E	0.573	0.54
183_R	498_Y	0.573	0.54
333_A	345_V	0.572	0.54
137_S	140_A	0.571	0.54
354_Y	366_F	0.571	0.54
452_E	482_K	0.570	0.54
511_L	514_I	0.570	0.54
302_V	308_T	0.569	0.54
584_F	593_R	0.568	0.53
332_Y	367_S	0.568	0.53
124_P	131_L	0.567	0.53
287_V	549_I	0.566	0.53
328_I	363_M	0.566	0.53
319_F	380_L	0.566	0.53
594_Y	597_D	0.566	0.53
147_A	180_L	0.565	0.53
94_K	105_Q	0.565	0.53
566_L	594_Y	0.564	0.53
396_E	400_E	0.564	0.53
231_Y	235_A	0.562	0.53
560_K	563_E	0.561	0.53
493_T	499_Q	0.561	0.53
97_N	119_Q	0.559	0.52
98_A	114_V	0.559	0.52
177_G	180_L	0.559	0.52
332_Y	379_L	0.559	0.52
315_L	588_L	0.558	0.52
385_P	438_F	0.558	0.52
458_I	558_M	0.558	0.52
583_E	586_S	0.558	0.52
407_V	426_A	0.557	0.52
291_V	311_L	0.556	0.52
282_N	287_V	0.556	0.52
406_G	462_T	0.556	0.52
275_A	552_C	0.555	0.52
131_L	486_F	0.555	0.52
272_P	408_V	0.554	0.52
283_D	287_V	0.554	0.52
589_R	597_D	0.554	0.52
393_S	398_E	0.554	0.52
81_A	85_D	0.554	0.52
60_E	177_G	0.553	0.52
281_Q	436_R	0.552	0.51
165_G	183_R	0.552	0.51
482_K	541_R	0.552	0.51
180_L	204_A	0.551	0.51
331_N	375_A	0.551	0.51
281_Q	316_Q	0.550	0.51
298_G	311_L	0.548	0.51
181_L	204_A	0.548	0.51
458_I	551_V	0.548	0.51
506_V	582_D	0.547	0.51
294_L	376_L	0.547	0.51
106_I	584_F	0.547	0.51
490_P	557_R	0.547	0.51
66_I	79_A	0.546	0.51
194_A	198_R	0.546	0.51
275_A	597_D	0.546	0.51
396_E	476_A	0.546	0.51
160_F	320_E	0.545	0.51
458_I	532_L	0.545	0.51
554_D	563_E	0.544	0.50
128_A	501_E	0.542	0.50
536_G	565_A	0.541	0.50
458_I	547_A	0.541	0.50
455_V	550_Y	0.541	0.50
525_K	534_E	0.540	0.50
223_V	579_E	0.540	0.50
62_P	110_K	0.540	0.50
141_P	144_E	0.540	0.50
184_V	202_V	0.540	0.50
460_P	464_I	0.540	0.50
278_V	403_V	0.539	0.50
278_V	394_Q	0.539	0.50
204_A	208_R	0.538	0.50
522_Q	525_K	0.538	0.50
65_T	96_V	0.538	0.50
289_E	361_V	0.538	0.50
241_L	403_V	0.536	0.49
576_M	581_A	0.535	0.49
155_D	599_Y	0.535	0.49
246_K	256_V	0.535	0.49
96_V	102_K	0.534	0.49
233_K	435_V	0.533	0.49
83_R	374_E	0.533	0.49
152_S	186_A	0.533	0.49
520_R	525_K	0.533	0.49
554_D	562_V	0.533	0.49
490_P	592_R	0.533	0.49
119_Q	128_A	0.532	0.49
77_R	95_L	0.531	0.49
406_G	460_P	0.530	0.49
445_F	597_D	0.530	0.49
567_L	570_I	0.530	0.49
485_L	514_I	0.529	0.48
143_L	200_R	0.529	0.48
284_P	565_A	0.529	0.48
248_T	407_V	0.528	0.48
68_S	540_W	0.528	0.48
84_D	89_A	0.528	0.48
564_Q	575_G	0.528	0.48
152_S	209_A	0.528	0.48
323_V	361_V	0.528	0.48
364_V	376_L	0.528	0.48
274_D	282_N	0.526	0.48
65_T	109_E	0.526	0.48
412_V	415_R	0.525	0.48
409_R	426_A	0.524	0.48
146_T	237_L	0.524	0.48
180_L	213_A	0.524	0.48
354_Y	357_T	0.524	0.48
531_K	539_L	0.523	0.48
375_A	378_N	0.522	0.48
560_K	597_D	0.522	0.48
456_I	545_D	0.522	0.48
423_S	427_D	0.521	0.47
332_Y	337_R	0.520	0.47
253_E	406_G	0.520	0.47
159_E	348_K	0.519	0.47
291_V	294_L	0.519	0.47
536_G	551_V	0.519	0.47
540_W	569_V	0.519	0.47
270_Y	501_E	0.518	0.47
207_S	416_A	0.518	0.47
275_A	389_S	0.518	0.47
112_L	172_L	0.518	0.47
63_G	91_L	0.518	0.47
237_L	268_M	0.517	0.47
140_A	171_K	0.516	0.47
164_S	167_D	0.516	0.47
452_E	480_P	0.516	0.47
68_S	533_R	0.516	0.47
242_S	507_K	0.516	0.47
91_L	211_V	0.516	0.47
139_K	142_K	0.515	0.47
63_G	110_K	0.514	0.47
261_I	276_L	0.514	0.47
75_A	127_E	0.514	0.47
89_A	202_V	0.514	0.47
64_I	111_L	0.513	0.46
302_V	314_A	0.513	0.46
146_T	280_Y	0.512	0.46
166_K	183_R	0.511	0.46
290_L	505_Y	0.511	0.46
66_I	80_E	0.511	0.46
178_E	208_R	0.510	0.46
260_E	472_Q	0.510	0.46
543_I	588_L	0.510	0.46
492_F	503_Q	0.509	0.46
453_T	474_R	0.509	0.46
239_A	436_R	0.508	0.46
69_A	242_S	0.507	0.46
310_P	314_A	0.507	0.46
339_E	452_E	0.506	0.46
116_T	119_Q	0.506	0.46
89_A	93_V	0.506	0.46
484_W	511_L	0.506	0.46
517_A	527_Y	0.505	0.45
257_R	426_A	0.505	0.45
109_E	117_S	0.504	0.45
119_Q	127_E	0.504	0.45
91_L	111_L	0.503	0.45
254_K	559_A	0.503	0.45
585_L	588_L	0.503	0.45
398_E	431_E	0.503	0.45
448_P	470_F	0.502	0.45
131_L	279_W	0.502	0.45
261_I	568_E	0.501	0.45
70_S	271_Q	0.501	0.45
79_A	176_G	0.501	0.45
182_D	591_E	0.501	0.45
460_P	486_F	0.500	0.45
124_P	489_N	0.500	0.45

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2bpoA	1	0.9115	100	0.302	Contact Map
3qe2A	1	0.9065	100	0.306	Contact Map
1tllA	2	0.8932	100	0.308	Contact Map
1ddgA	1	0.6227	100	0.49	Contact Map
1f20A	1	0.6528	100	0.496	Contact Map
2qtlA	1	0.6561	100	0.508	Contact Map
3qfsA	1	0.6644	100	0.51	Contact Map
4dqlA	2	0.6043	100	0.534	Contact Map
2bmwA	1	0.4574	100	0.746	Contact Map
2b5oA	1	0.4574	100	0.751	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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