MPL - ECOLI - GREMLIN Contacts

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MPL - UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase

UniProt:	P37773	Sequences: MRIHILGICGTFMGGLAMLARQLGHEVTGSDANVYPPMSTLLEKQGIELIQGYDASQLEPQPDLVIIGNAMTRGNPCVEAVLEKNIPYMSGPQWLHDFVLRDRWVLAVAGTHGKTTTAGMATWILEQCGYKPGFVIGGVPGNFEVSAHLGESDFFVIEADEYDCAFFDKRSKFVHYCPRTLILNNLEFDHADIFDDLKAIQKQFHHLVRIVPGQGRIIWPENDINLKQTMAMGCWSEQELVGEQGHWQAKKLTTDASEWEVLLDGEKVGEVKWSLVGEHNMHNGLMAIAAARHVGVAPADAANALGSFINARRRLELRGEANGVTVYDDFAHHPTAILATLAALRGKVGGTARIIAVLEPRSNTMKMGICKDDLAPSLGRADEVFLLQPAHIPWQVAEVAEACVQPAHWSGDVDTLADMVVKTAQPGDHILVMSNGGFGGIHQKLLDGLAKKAEAAQ	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG12440
Length:	457 (403)
Sequences:	18588 (13884)
Seq/√Len:	691.6

ECOLI - MPL MURC MURD MURE MURF
BACSU - MURD MURC MURE MURF

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
182_I	290_A	3.533	1.00
356_A	381_A	2.692	1.00
127_Q	307_S	2.638	1.00
27_V	39_S	2.624	1.00
104_W	179_R	2.561	1.00
251_K	260_E	2.518	1.00
180_T	290_A	2.498	1.00
408_H	419_M	2.489	1.00
383_E	408_H	2.488	1.00
297_A	300_D	2.484	1.00
288_I	301_A	2.447	1.00
410_S	419_M	2.436	1.00
250_K	262_L	2.430	1.00
182_I	286_M	2.387	1.00
396_V	399_V	2.360	1.00
412_D	415_T	2.354	1.00
419_M	423_T	2.345	1.00
317_L	325_T	2.337	1.00
196_D	199_A	2.324	1.00
260_E	270_E	2.294	1.00
124_I	291_A	2.268	1.00
80_A	83_E	2.248	1.00
383_E	423_T	2.213	1.00
272_K	306_G	2.197	1.00
127_Q	304_A	2.193	1.00
124_I	287_A	2.169	1.00
363_N	393_P	2.135	1.00
221_E	245_G	2.127	1.00
141_G	144_E	2.100	1.00
201_Q	228_Q	2.066	1.00
216_R	293_H	2.041	1.00
195_D	199_A	2.002	1.00
56_S	60_P	1.993	1.00
273_W	284_G	1.988	1.00
239_E	286_M	1.977	1.00
397_A	401_E	1.962	1.00
419_M	422_K	1.927	1.00
56_S	59_E	1.920	1.00
42_L	66_I	1.920	1.00
247_W	289_A	1.919	1.00
208_V	217_I	1.915	1.00
179_R	215_G	1.910	1.00
80_A	84_K	1.906	1.00
127_Q	303_N	1.899	1.00
128_C	300_D	1.848	1.00
338_L	342_A	1.839	1.00
107_A	178_P	1.829	1.00
385_F	423_T	1.828	1.00
123_W	307_S	1.803	1.00
107_A	159_A	1.797	1.00
424_A	430_I	1.791	1.00
121_A	287_A	1.781	1.00
205_H	232_M	1.772	1.00
106_L	294_V	1.767	1.00
317_L	327_Y	1.765	1.00
258_E	270_E	1.759	1.00
58_L	76_P	1.718	1.00
130_Y	153_D	1.688	1.00
260_E	267_K	1.684	1.00
55_A	59_E	1.682	1.00
262_L	267_K	1.678	1.00
201_Q	225_N	1.661	1.00
122_T	126_E	1.661	1.00
292_R	298_P	1.656	1.00
199_A	202_K	1.654	1.00
121_A	290_A	1.642	1.00
284_G	305_L	1.640	1.00
258_E	272_K	1.630	1.00
361_R	437_G	1.622	1.00
385_F	419_M	1.618	1.00
263_L	292_R	1.617	1.00
122_T	135_V	1.601	1.00
187_E	335_T	1.598	1.00
259_W	284_G	1.596	1.00
181_L	207_L	1.582	1.00
278_E	346_G	1.569	1.00
104_W	154_F	1.566	1.00
398_E	401_E	1.558	1.00
180_T	294_V	1.557	1.00
203_Q	206_H	1.546	1.00
108_V	121_A	1.542	1.00
375_A	379_G	1.533	1.00
249_A	285_L	1.528	1.00
128_C	296_V	1.516	1.00
248_Q	262_L	1.513	1.00
121_A	291_A	1.510	1.00
291_A	301_A	1.500	1.00
105_V	176_Y	1.491	1.00
181_L	211_V	1.490	1.00
320_E	325_T	1.484	1.00
161_E	194_F	1.482	1.00
302_A	306_G	1.476	1.00
29_G	34_V	1.473	1.00
355_I	423_T	1.467	1.00
123_W	304_A	1.459	1.00
165_A	203_Q	1.454	1.00
45_Q	68_G	1.447	1.00
106_L	121_A	1.443	1.00
263_L	266_E	1.425	1.00
116_T	280_N	1.413	1.00
211_V	215_G	1.408	1.00
326_V	421_V	1.406	1.00
410_S	415_T	1.391	1.00
303_N	307_S	1.391	1.00
125_L	294_V	1.388	1.00
324_V	424_A	1.387	1.00
398_E	402_A	1.381	1.00
108_V	118_A	1.375	1.00
154_F	294_V	1.362	1.00
237_E	240_L	1.361	1.00
218_I	293_H	1.357	1.00
300_D	303_N	1.356	1.00
238_Q	241_V	1.352	1.00
125_L	156_V	1.351	1.00
186_L	201_Q	1.346	1.00
353_R	383_E	1.340	1.00
278_E	342_A	1.333	1.00
29_G	35_Y	1.324	1.00
117_T	184_N	1.320	1.00
237_E	241_V	1.316	1.00
247_W	292_R	1.310	1.00
120_M	308_F	1.306	1.00
361_R	389_P	1.302	1.00
111_T	189_D	1.300	1.00
274_S	309_I	1.300	1.00
115_T	311_A	1.300	1.00
188_F	191_A	1.294	1.00
145_V	149_L	1.287	1.00
165_A	193_I	1.276	1.00
180_T	293_H	1.271	1.00
395_Q	398_E	1.267	1.00
40_T	43_E	1.265	1.00
399_V	403_C	1.263	1.00
131_K	153_D	1.261	1.00
164_C	203_Q	1.260	1.00
357_V	387_L	1.257	1.00
36_P	39_S	1.252	1.00
291_A	296_V	1.249	1.00
94_W	98_F	1.239	1.00
120_M	275_L	1.235	1.00
220_P	282_H	1.232	1.00
355_I	385_F	1.231	1.00
342_A	380_R	1.229	1.00
183_L	186_L	1.228	1.00
112_H	333_H	1.227	1.00
104_W	153_D	1.225	1.00
79_E	82_L	1.224	1.00
180_T	218_I	1.220	1.00
352_A	428_D	1.217	1.00
249_A	252_L	1.211	1.00
68_G	84_K	1.205	1.00
312_R	316_E	1.203	1.00
315_L	344_L	1.201	1.00
280_N	283_N	1.199	1.00
219_W	238_Q	1.195	1.00
387_L	416_L	1.195	1.00
342_A	377_S	1.191	1.00
415_T	418_D	1.188	1.00
385_F	416_L	1.188	1.00
177_C	215_G	1.186	1.00
29_G	39_S	1.185	1.00
397_A	409_W	1.183	1.00
67_I	78_V	1.182	1.00
261_V	288_I	1.176	1.00
394_W	398_E	1.175	1.00
259_W	281_M	1.174	1.00
317_L	320_E	1.167	1.00
353_R	428_D	1.166	1.00
125_L	154_F	1.161	1.00
315_L	327_Y	1.161	1.00
383_E	406_P	1.157	1.00
228_Q	231_A	1.145	1.00
323_G	426_P	1.142	1.00
253_T	258_E	1.142	1.00
198_K	202_K	1.137	1.00
418_D	422_K	1.137	1.00
219_W	226_L	1.135	1.00
202_K	232_M	1.133	1.00
216_R	237_E	1.133	1.00
241_V	278_E	1.132	1.00
353_R	382_D	1.131	1.00
250_K	260_E	1.117	1.00
205_H	229_T	1.111	1.00
303_N	306_G	1.109	1.00
40_T	44_K	1.108	1.00
179_R	212_P	1.098	1.00
121_A	182_I	1.097	1.00
225_N	228_Q	1.095	1.00
159_A	173_F	1.094	1.00
112_H	336_A	1.086	1.00
278_E	282_H	1.083	1.00
173_F	176_Y	1.078	1.00
130_Y	154_F	1.076	1.00
299_A	303_N	1.071	1.00
355_I	383_E	1.063	1.00
222_N	282_H	1.060	1.00
188_F	197_L	1.059	1.00
106_L	290_A	1.057	1.00
188_F	367_M	1.055	1.00
337_I	433_M	1.051	1.00
218_I	289_A	1.049	1.00
125_L	296_V	1.046	1.00
219_W	230_M	1.042	1.00
197_L	225_N	1.042	1.00
206_H	209_R	1.039	1.00
236_S	240_L	1.035	1.00
386_L	409_W	1.035	1.00
184_N	286_M	1.034	1.00
320_E	323_G	1.030	1.00
183_L	208_V	1.024	1.00
249_A	281_M	1.024	1.00
221_E	227_K	1.020	1.00
415_T	419_M	1.018	1.00
198_K	225_N	1.018	1.00
123_W	126_E	1.018	1.00
128_C	304_A	1.015	1.00
414_D	418_D	1.013	1.00
396_V	403_C	1.013	1.00
332_H	337_I	1.009	1.00
425_Q	428_D	1.003	1.00
131_K	151_E	0.998	1.00
393_P	396_V	0.998	1.00
256_A	272_K	0.998	1.00
296_V	300_D	0.998	1.00
339_A	342_A	0.992	1.00
172_K	175_H	0.991	1.00
40_T	64_L	0.990	1.00
211_V	217_I	0.984	1.00
120_M	284_G	0.984	1.00
356_A	433_M	0.981	1.00
374_L	403_C	0.979	1.00
372_D	376_P	0.978	1.00
320_E	324_V	0.978	1.00
93_Q	97_D	0.978	1.00
70_A	80_A	0.977	1.00
221_E	238_Q	0.973	1.00
201_Q	205_H	0.968	1.00
202_K	206_H	0.966	1.00
247_W	263_L	0.965	1.00
388_Q	411_G	0.964	1.00
238_Q	246_H	0.962	1.00
124_I	304_A	0.959	1.00
316_E	328_D	0.959	1.00
105_V	155_F	0.955	1.00
385_F	410_S	0.955	1.00
144_E	147_A	0.951	1.00
58_L	65_V	0.951	1.00
122_T	132_P	0.946	1.00
374_L	378_L	0.935	1.00
206_H	210_I	0.932	1.00
124_I	301_A	0.932	1.00
79_E	83_E	0.932	1.00
122_T	134_F	0.929	1.00
180_T	216_R	0.928	1.00
123_W	308_F	0.925	1.00
237_E	289_A	0.920	1.00
98_F	101_R	0.919	1.00
366_K	369_I	0.919	1.00
259_W	271_V	0.917	1.00
104_W	294_V	0.917	1.00
54_D	57_Q	0.917	1.00
400_A	403_C	0.914	1.00
84_K	87_P	0.914	1.00
324_V	427_G	0.911	1.00
90_S	93_Q	0.910	1.00
408_H	423_T	0.907	1.00
216_R	235_W	0.905	1.00
134_F	138_G	0.903	1.00
266_E	298_P	0.903	1.00
227_K	231_A	0.902	1.00
32_A	35_Y	0.901	1.00
85_N	89_M	0.899	1.00
313_R	328_D	0.898	1.00
340_T	431_L	0.897	1.00
251_K	254_T	0.896	1.00
127_Q	300_D	0.895	1.00
242_G	245_G	0.894	1.00
385_F	420_V	0.894	1.00
255_D	258_E	0.893	1.00
54_D	65_V	0.892	1.00
209_R	232_M	0.890	1.00
162_Y	193_I	0.890	1.00
109_A	204_F	0.885	1.00
69_N	72_T	0.883	1.00
298_P	302_A	0.882	1.00
271_V	302_A	0.881	1.00
112_H	335_T	0.880	1.00
396_V	400_A	0.879	1.00
224_I	228_Q	0.875	1.00
223_D	282_H	0.871	1.00
370_C	373_D	0.868	1.00
376_P	379_G	0.864	1.00
199_A	203_Q	0.862	1.00
290_A	294_V	0.858	1.00
333_H	336_A	0.856	1.00
183_L	229_T	0.855	1.00
87_P	97_D	0.855	1.00
26_E	38_M	0.854	1.00
399_V	402_A	0.853	1.00
35_Y	39_S	0.851	1.00
131_K	152_S	0.849	1.00
373_D	376_P	0.848	1.00
389_P	392_I	0.847	1.00
128_C	297_A	0.847	1.00
392_I	395_Q	0.847	1.00
54_D	58_L	0.843	1.00
93_Q	175_H	0.841	1.00
411_G	415_T	0.841	1.00
288_I	292_R	0.835	1.00
381_A	384_V	0.835	1.00
348_V	429_H	0.832	1.00
420_V	424_A	0.828	1.00
107_A	207_L	0.828	1.00
134_F	137_G	0.827	1.00
49_L	53_Y	0.825	1.00
348_V	352_A	0.822	1.00
45_Q	69_N	0.822	1.00
250_K	267_K	0.819	1.00
292_R	301_A	0.819	1.00
245_G	248_Q	0.818	1.00
40_T	66_I	0.815	1.00
89_M	93_Q	0.814	1.00
78_V	82_L	0.808	1.00
205_H	209_R	0.803	1.00
164_C	199_A	0.802	1.00
279_H	339_A	0.799	1.00
325_T	429_H	0.798	1.00
218_I	290_A	0.796	1.00
123_W	127_Q	0.792	1.00
141_G	145_V	0.789	1.00
119_G	311_A	0.780	1.00
159_A	178_P	0.780	1.00
220_P	223_D	0.778	1.00
194_F	203_Q	0.775	1.00
355_I	424_A	0.774	1.00
404_V	407_A	0.773	1.00
275_L	308_F	0.772	1.00
268_V	302_A	0.770	1.00
105_V	157_I	0.770	1.00
188_F	335_T	0.768	1.00
112_H	187_E	0.767	1.00
416_L	420_V	0.766	1.00
57_Q	62_P	0.765	1.00
115_T	138_G	0.765	1.00
369_I	373_D	0.765	1.00
335_T	339_A	0.764	1.00
88_Y	91_G	0.764	1.00
337_I	358_L	0.762	1.00
361_R	392_I	0.761	1.00
240_L	282_H	0.758	1.00
117_T	287_A	0.758	1.00
243_E	248_Q	0.758	1.00
237_E	293_H	0.757	1.00
119_G	139_V	0.757	1.00
86_I	90_S	0.755	1.00
235_W	293_H	0.755	1.00
117_T	286_M	0.754	1.00
197_L	201_Q	0.752	1.00
221_E	226_L	0.752	1.00
347_K	429_H	0.751	1.00
177_C	212_P	0.751	1.00
221_E	242_G	0.750	1.00
88_Y	92_P	0.750	1.00
92_P	96_H	0.749	1.00
219_W	236_S	0.747	1.00
392_I	396_V	0.745	1.00
327_Y	429_H	0.744	1.00
410_S	416_L	0.742	1.00
28_T	62_P	0.742	1.00
366_K	402_A	0.740	1.00
164_C	202_K	0.739	1.00
135_V	138_G	0.739	1.00
85_N	88_Y	0.734	1.00
198_K	201_Q	0.733	1.00
87_P	91_G	0.733	1.00
338_L	373_D	0.732	1.00
172_K	176_Y	0.727	1.00
34_V	43_E	0.724	1.00
65_V	81_V	0.724	1.00
136_I	140_P	0.724	1.00
161_E	203_Q	0.724	1.00
250_K	254_T	0.722	1.00
358_L	386_L	0.722	1.00
338_L	376_P	0.720	1.00
417_A	421_V	0.720	1.00
77_C	80_A	0.720	1.00
386_L	407_A	0.719	1.00
253_T	270_E	0.718	1.00
164_C	193_I	0.716	1.00
43_E	51_Q	0.715	1.00
241_V	249_A	0.714	1.00
41_L	45_Q	0.714	1.00
341_L	345_R	0.710	1.00
357_V	432_V	0.709	1.00
259_W	262_L	0.709	1.00
342_A	346_G	0.708	1.00
296_V	301_A	0.706	1.00
368_G	372_D	0.705	1.00
217_I	233_G	0.703	1.00
385_F	408_H	0.702	1.00
122_T	156_V	0.699	1.00
228_Q	232_M	0.695	1.00
241_V	252_L	0.693	1.00
103_R	155_F	0.693	1.00
89_M	92_P	0.692	1.00
128_C	291_A	0.691	1.00
323_G	427_G	0.691	1.00
386_L	400_A	0.690	1.00
338_L	379_G	0.689	1.00
349_G	352_A	0.689	1.00
187_E	197_L	0.688	1.00
145_V	148_H	0.688	1.00
288_I	298_P	0.686	1.00
240_L	245_G	0.684	1.00
137_G	140_P	0.682	1.00
254_T	278_E	0.682	1.00
376_P	380_R	0.678	1.00
125_L	291_A	0.678	1.00
355_I	420_V	0.677	1.00
74_G	77_C	0.677	1.00
322_N	426_P	0.677	1.00
396_V	402_A	0.677	1.00
227_K	230_M	0.676	1.00
42_L	88_Y	0.674	1.00
358_L	434_S	0.673	1.00
338_L	377_S	0.673	1.00
198_K	228_Q	0.673	1.00
344_L	431_L	0.672	1.00
301_A	304_A	0.672	1.00
165_A	199_A	0.671	1.00
396_V	401_E	0.671	1.00
118_A	156_V	0.669	1.00
84_K	88_Y	0.667	1.00
238_Q	245_G	0.666	1.00
202_K	205_H	0.664	1.00
30_S	49_L	0.663	1.00
326_V	430_I	0.661	1.00
197_L	200_I	0.659	1.00
240_L	248_Q	0.659	1.00
372_D	402_A	0.657	1.00
52_G	68_G	0.657	1.00
374_L	377_S	0.657	1.00
382_D	425_Q	0.657	1.00
189_D	333_H	0.656	1.00
226_L	229_T	0.655	1.00
119_G	123_W	0.654	1.00
43_E	54_D	0.653	1.00
35_Y	62_P	0.651	1.00
201_Q	229_T	0.651	1.00
397_A	411_G	0.650	1.00
183_L	201_Q	0.649	1.00
124_I	128_C	0.649	1.00
186_L	197_L	0.648	1.00
375_A	378_L	0.643	1.00
121_A	156_V	0.642	1.00
387_L	413_V	0.642	1.00
92_P	159_A	0.641	1.00
241_V	282_H	0.641	1.00
246_H	264_D	0.638	1.00
39_S	43_E	0.634	1.00
315_L	343_A	0.633	1.00
313_R	436_G	0.632	1.00
89_M	97_D	0.631	1.00
355_I	428_D	0.630	1.00
136_I	139_V	0.629	1.00
349_G	429_H	0.629	1.00
394_W	409_W	0.629	1.00
389_P	394_W	0.628	1.00
135_V	140_P	0.626	1.00
321_A	324_V	0.626	1.00
226_L	230_M	0.623	1.00
261_V	285_L	0.621	1.00
285_L	289_A	0.620	1.00
288_I	305_L	0.617	1.00
357_V	420_V	0.616	1.00
397_A	400_A	0.615	1.00
386_L	403_C	0.615	1.00
119_G	140_P	0.613	1.00
42_L	84_K	0.612	1.00
268_V	298_P	0.612	1.00
31_D	34_V	0.611	1.00
299_A	302_A	0.608	1.00
41_L	44_K	0.607	1.00
236_S	239_E	0.605	1.00
326_V	432_V	0.605	1.00
271_V	284_G	0.603	1.00
275_L	280_N	0.602	1.00
413_V	417_A	0.602	1.00
352_A	425_Q	0.602	1.00
173_F	210_I	0.601	1.00
397_A	403_C	0.601	1.00
264_D	292_R	0.600	1.00
135_V	139_V	0.599	1.00
108_V	182_I	0.599	1.00
257_S	261_V	0.598	1.00
120_M	287_A	0.597	1.00
106_L	154_F	0.597	1.00
50_I	69_N	0.597	1.00
116_T	120_M	0.597	1.00
337_I	341_L	0.596	1.00
372_D	375_A	0.596	1.00
353_R	425_Q	0.596	1.00
93_Q	98_F	0.595	1.00
73_R	82_L	0.593	1.00
50_I	57_Q	0.588	1.00
331_A	433_M	0.588	1.00
65_V	76_P	0.588	1.00
357_V	416_L	0.587	1.00
52_G	84_K	0.587	1.00
383_E	419_M	0.587	1.00
177_C	210_I	0.587	1.00
255_D	272_K	0.586	1.00
164_C	194_F	0.586	1.00
65_V	78_V	0.584	1.00
53_Y	57_Q	0.584	1.00
106_L	125_L	0.584	1.00
74_G	79_E	0.583	1.00
124_I	296_V	0.583	1.00
277_G	280_N	0.582	1.00
394_W	397_A	0.581	1.00
93_Q	96_H	0.579	1.00
257_S	260_E	0.579	1.00
57_Q	61_Q	0.578	1.00
392_I	399_V	0.577	1.00
330_F	436_G	0.575	1.00
251_K	270_E	0.573	1.00
257_S	281_M	0.573	1.00
163_D	193_I	0.573	1.00
74_G	78_V	0.572	1.00
101_R	177_C	0.572	1.00
389_P	395_Q	0.571	1.00
102_D	148_H	0.570	1.00
27_V	36_P	0.568	1.00
278_E	281_M	0.567	1.00
32_A	53_Y	0.567	1.00
400_A	409_W	0.567	1.00
387_L	410_S	0.566	1.00
254_T	257_S	0.565	1.00
338_L	380_R	0.565	1.00
140_P	143_F	0.563	1.00
191_A	195_D	0.563	1.00
184_N	239_E	0.558	1.00
288_I	302_A	0.558	1.00
26_E	48_E	0.557	1.00
34_V	40_T	0.557	1.00
366_K	370_C	0.555	1.00
243_E	250_K	0.555	1.00
388_Q	400_A	0.554	1.00
418_D	421_V	0.553	1.00
242_G	278_E	0.553	1.00
82_L	88_Y	0.553	1.00
331_A	340_T	0.553	1.00
340_T	433_M	0.552	1.00
227_K	238_Q	0.552	1.00
160_D	163_D	0.551	1.00
352_A	427_G	0.551	1.00
289_A	293_H	0.549	1.00
132_P	135_V	0.546	1.00
146_S	149_L	0.544	1.00
116_T	308_F	0.542	1.00
259_W	263_L	0.542	1.00
244_Q	248_Q	0.541	1.00
71_M	78_V	0.540	1.00
281_M	285_L	0.540	1.00
345_R	348_V	0.540	1.00
91_G	94_W	0.539	1.00
273_W	305_L	0.538	1.00
59_E	84_K	0.537	1.00
118_A	135_V	0.535	1.00
89_M	175_H	0.533	1.00
230_M	233_G	0.532	1.00
242_G	248_Q	0.531	1.00
221_E	240_L	0.530	1.00
275_L	310_N	0.529	1.00
179_R	214_Q	0.529	1.00
286_M	290_A	0.527	1.00
359_E	438_F	0.526	1.00
189_D	204_F	0.523	1.00
382_D	428_D	0.523	1.00
361_R	439_G	0.521	1.00
229_T	233_G	0.520	1.00
28_T	42_L	0.519	1.00
362_S	393_P	0.519	1.00
25_H	64_L	0.519	1.00
91_G	96_H	0.519	1.00
132_P	156_V	0.518	1.00
298_P	301_A	0.518	1.00
108_V	117_T	0.517	0.99
356_A	384_V	0.517	0.99
360_P	363_N	0.516	0.99
100_L	177_C	0.516	0.99
290_A	293_H	0.515	0.99
322_N	421_V	0.513	0.99
191_A	196_D	0.512	0.99
142_N	145_V	0.511	0.99
66_I	91_G	0.511	0.99
159_A	176_Y	0.510	0.99
126_E	132_P	0.509	0.99
420_V	430_I	0.508	0.99
116_T	283_N	0.507	0.99
131_K	150_G	0.503	0.99
124_I	305_L	0.502	0.99
181_L	214_Q	0.501	0.99
247_W	293_H	0.500	0.99

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2x5oA	1	0.9344	100	0.23	Contact Map
3hn7A	1	0.9803	100	0.231	Contact Map
3lk7A	1	0.9409	100	0.243	Contact Map
1p3dA	1	0.9562	100	0.25	Contact Map
4hv4A	1	0.9628	100	0.266	Contact Map
1j6uA	1	0.9147	100	0.268	Contact Map
4bucA	1	0.8972	100	0.271	Contact Map
4c12A	2	0.9672	100	0.294	Contact Map
4bubA	1	0.9475	100	0.303	Contact Map
4qdiA	1	0.9344	100	0.315	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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