YDIF - ECOLI - GREMLIN Contacts

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YDIF - Acetate CoA-transferase YdiF

UniProt:	P37766	Sequences: MKPVKPPRINGRVPVLSAQEAVNYIPDEATLCVLGAGGGILEATTLITALADKYKQTQTPRNLSIISPTGLGDRADRGISPLAQEGLVKWALCGHWGQSPRISELAEQNKIIAYNYPQGVLTQTLRAAAAHQPGIISDIGIGTFVDPRQQGGKLNEVTKEDLIKLVEFDNKEYLYYKAIAPDIAFIRATTCDSEGYATFEDEVMYLDALVIAQAVHNNGGIVMMQVQKMVKKATLHPKSVRIPGYLVDIVVVDPDQTQLYGGAPVNRFISGDFTLDDSTKLSLPLNQRKLVARRALFEMRKGAVGNVGVGIADGIGLVAREEGCADDFILTVETGPIGGITSQGIAFGANVNTRAILDMTSQFDFYHGGGLDVCYLSFAEVDQHGNVGVHKFNGKIMGTGGFIDISATSKKIIFCGTLTAGSLKTEITDGKLNIVQEGRVKKFIRELPEITFSGKIALERGLDVRYITERAVFTLKEDGLHLIEIAPGVDLQKDILDKMDFTPVISPELKLMDERLFIDAAMGFVLPEAAH	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG12432
Length:	531 (463)
Sequences:	1030 (667)
Seq/√Len:	31.0

ECOLI - YDIF
HALSA - Q9HHP2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
492_Q	497_D	5.841	1.00
188_A	197_A	5.519	1.00
197_A	224_M	4.663	1.00
485_I	491_L	4.557	1.00
46_L	185_F	4.546	1.00
85_E	110_K	4.318	1.00
26_P	29_A	4.306	1.00
148_R	165_L	4.064	1.00
193_S	231_K	3.868	1.00
138_D	171_K	3.856	1.00
51_A	84_Q	3.449	1.00
382_D	386_N	3.400	1.00
89_K	112_I	3.322	1.00
506_S	509_L	3.292	1.00
27_D	59_T	3.288	1.00
383_Q	445_R	3.284	1.00
153_K	161_D	3.114	1.00
82_L	87_L	3.080	1.00
19_Q	52_D	3.007	1.00
104_E	108_Q	3.004	1.00
201_D	227_Q	2.995	1.00
148_R	172_E	2.977	1.00
186_I	242_I	2.970	1.00
127_A	135_I	2.961	1.00
164_K	169_D	2.914	1.00
235_L	240_V	2.873	1.00
186_I	224_M	2.844	1.00
190_T	230_V	2.817	1.00
445_R	500_D	2.747	1.00
465_R	483_I	2.604	1.00
380_E	448_P	2.596	1.00
367_H	404_D	2.567	1.00
66_I	179_I	2.519	0.99
136_I	166_V	2.493	0.99
16_L	249_I	2.486	0.99
194_E	232_K	2.454	0.99
139_I	408_T	2.442	0.99
31_L	185_F	2.434	0.99
45_T	256_Q	2.376	0.99
224_M	242_I	2.376	0.99
476_K	481_H	2.370	0.99
441_K	500_D	2.363	0.99
197_A	242_I	2.362	0.99
474_T	483_I	2.357	0.99
263_A	346_A	2.310	0.99
481_H	506_S	2.305	0.99
90_W	112_I	2.292	0.99
42_E	47_I	2.288	0.99
184_A	215_V	2.223	0.99
17_S	20_E	2.209	0.99
28_E	62_N	2.185	0.99
25_I	50_L	2.161	0.98
165_L	172_E	2.109	0.98
127_A	132_Q	2.094	0.98
105_L	110_K	2.070	0.98
16_L	22_V	2.047	0.98
134_G	175_Y	2.023	0.98
190_T	200_E	2.013	0.97
18_A	49_A	1.997	0.97
201_D	272_D	1.919	0.97
120_V	137_S	1.919	0.97
499_M	503_P	1.917	0.97
50_L	185_F	1.913	0.97
190_T	228_K	1.903	0.96
381_V	443_F	1.888	0.96
465_R	474_T	1.868	0.96
236_H	239_S	1.840	0.96
505_I	509_L	1.836	0.96
265_V	272_D	1.809	0.95
331_T	366_Y	1.793	0.95
64_S	92_L	1.790	0.95
128_A	179_I	1.790	0.95
441_K	498_K	1.760	0.94
142_G	456_I	1.757	0.94
221_I	249_I	1.735	0.94
231_K	234_T	1.710	0.93
198_T	235_L	1.702	0.93
29_A	182_D	1.698	0.93
474_T	481_H	1.694	0.93
167_E	172_E	1.686	0.93
22_V	25_I	1.680	0.93
221_I	224_M	1.680	0.93
194_E	354_R	1.656	0.92
188_A	224_M	1.579	0.90
481_H	504_V	1.553	0.90
476_K	479_G	1.552	0.90
20_E	23_N	1.551	0.90
116_Y	162_L	1.550	0.90
473_F	482_L	1.547	0.89
109_N	156_E	1.534	0.89
199_F	208_A	1.533	0.89
142_G	459_E	1.530	0.89
492_Q	502_T	1.522	0.89
149_Q	450_I	1.520	0.89
32_C	211_I	1.516	0.88
175_Y	178_A	1.511	0.88
15_V	229_M	1.491	0.88
29_A	183_I	1.490	0.88
358_D	361_S	1.489	0.88
62_N	89_K	1.483	0.87
136_I	175_Y	1.476	0.87
88_V	102_I	1.467	0.87
169_D	177_K	1.459	0.86
491_L	495_I	1.458	0.86
211_I	215_V	1.447	0.86
399_T	451_T	1.442	0.86
245_Y	337_I	1.428	0.85
33_V	71_L	1.418	0.85
479_G	504_V	1.415	0.85
491_L	496_L	1.403	0.84
27_D	61_R	1.400	0.84
420_A	437_E	1.398	0.84
181_P	215_V	1.394	0.84
485_I	509_L	1.393	0.84
312_A	377_S	1.392	0.84
85_E	108_Q	1.386	0.83
22_V	50_L	1.382	0.83
127_A	130_A	1.370	0.83
476_K	506_S	1.366	0.83
289_K	321_E	1.352	0.82
76_D	80_S	1.349	0.82
193_S	234_T	1.342	0.81
443_F	480_L	1.335	0.81
36_A	334_T	1.328	0.81
381_V	480_L	1.327	0.81
269_I	346_A	1.313	0.80
101_R	104_E	1.306	0.80
21_A	53_K	1.304	0.79
336_P	350_N	1.293	0.79
32_C	181_P	1.289	0.79
49_A	53_K	1.288	0.79
487_P	511_L	1.287	0.79
123_Q	132_Q	1.284	0.78
22_V	53_K	1.274	0.78
185_F	223_M	1.273	0.78
163_I	174_L	1.265	0.77
183_I	221_I	1.258	0.77
289_K	322_E	1.258	0.77
45_T	48_T	1.250	0.76
64_S	90_W	1.239	0.76
184_A	224_M	1.230	0.75
247_V	250_V	1.225	0.75
381_V	387_V	1.220	0.75
25_I	185_F	1.216	0.74
299_M	305_G	1.216	0.74
257_T	260_Y	1.212	0.74
379_A	392_F	1.208	0.74
142_G	455_K	1.208	0.74
183_I	215_V	1.206	0.74
50_L	87_L	1.205	0.74
378_F	387_V	1.204	0.74
472_V	484_E	1.201	0.73
413_I	467_I	1.196	0.73
22_V	223_M	1.195	0.73
133_P	173_Y	1.191	0.73
494_D	498_K	1.160	0.71
420_A	439_R	1.155	0.71
24_Y	29_A	1.152	0.70
502_T	505_I	1.144	0.70
191_C	247_V	1.136	0.69
223_M	251_V	1.134	0.69
437_E	498_K	1.131	0.69
122_T	359_M	1.130	0.69
495_I	505_I	1.127	0.69
291_V	311_I	1.127	0.69
378_F	381_V	1.126	0.69
25_I	29_A	1.125	0.68
32_C	125_L	1.121	0.68
136_I	168_F	1.118	0.68
90_W	162_L	1.108	0.67
378_F	416_G	1.104	0.67
24_Y	249_I	1.102	0.67
109_N	157_V	1.101	0.67
300_R	303_A	1.100	0.67
288_R	311_I	1.099	0.67
199_F	242_I	1.097	0.66
66_I	92_L	1.089	0.66
51_A	81_P	1.086	0.66
419_T	469_E	1.086	0.66
485_I	495_I	1.085	0.66
45_T	253_D	1.083	0.65
230_V	273_F	1.073	0.65
36_A	312_A	1.070	0.64
128_A	180_A	1.070	0.64
315_I	375_Y	1.069	0.64
96_W	106_A	1.068	0.64
72_G	376_L	1.065	0.64
165_L	174_L	1.061	0.64
384_H	455_K	1.061	0.64
380_E	444_I	1.054	0.63
190_T	198_T	1.053	0.63
411_K	465_R	1.048	0.63
471_A	509_L	1.046	0.63
155_N	159_K	1.042	0.62
253_D	256_Q	1.037	0.62
470_R	498_K	1.036	0.62
98_Q	309_V	1.030	0.61
236_H	272_D	1.016	0.60
295_A	375_Y	1.006	0.60
491_L	509_L	1.005	0.60
478_D	504_V	1.000	0.59
115_N	399_T	0.996	0.59
46_L	50_L	0.994	0.59
93_C	96_W	0.991	0.58
466_Y	475_L	0.982	0.58
263_A	266_N	0.981	0.58
156_E	159_K	0.979	0.58
145_V	403_I	0.977	0.57
294_R	484_E	0.969	0.57
288_R	314_G	0.968	0.57
263_A	269_I	0.962	0.56
93_C	98_Q	0.960	0.56
23_N	27_D	0.956	0.56
283_L	314_G	0.956	0.56
292_A	315_I	0.947	0.55
375_Y	415_C	0.941	0.55
80_S	98_Q	0.939	0.54
486_A	512_M	0.938	0.54
16_L	24_Y	0.936	0.54
365_F	370_G	0.933	0.54
116_Y	121_L	0.930	0.54
167_E	170_N	0.930	0.54
36_A	309_V	0.928	0.53
437_E	441_K	0.927	0.53
193_S	232_K	0.927	0.53
504_V	508_E	0.924	0.53
205_Y	358_D	0.919	0.53
231_K	274_T	0.918	0.53
83_A	105_L	0.917	0.53
374_C	412_I	0.913	0.52
80_S	309_V	0.910	0.52
373_V	411_K	0.909	0.52
65_I	88_V	0.907	0.52
27_D	62_N	0.905	0.52
471_A	495_I	0.904	0.52
316_G	319_A	0.901	0.51
241_R	358_D	0.899	0.51
357_L	362_Q	0.890	0.50
289_K	293_R	0.887	0.50
207_D	360_T	0.886	0.50
123_Q	135_I	0.886	0.50
456_I	459_E	0.885	0.50
421_G	439_R	0.882	0.50
298_E	465_R	0.879	0.50
169_D	175_Y	0.878	0.49
37_G	313_D	0.877	0.49
445_R	502_T	0.876	0.49
504_V	507_P	0.875	0.49
181_P	184_A	0.869	0.49
141_I	146_D	0.868	0.49
309_V	313_D	0.866	0.48
124_T	179_I	0.865	0.48
41_L	206_L	0.864	0.48
281_L	284_P	0.864	0.48
184_A	211_I	0.863	0.48
481_H	507_P	0.863	0.48
197_A	247_V	0.863	0.48
489_V	494_D	0.856	0.48
60_P	240_V	0.856	0.48
303_A	373_V	0.856	0.48
44_T	81_P	0.855	0.48
116_Y	163_I	0.852	0.47
266_N	269_I	0.851	0.47
470_R	494_D	0.850	0.47
293_R	467_I	0.849	0.47
494_D	497_D	0.846	0.47
129_A	399_T	0.841	0.46
200_E	228_K	0.840	0.46
387_V	399_T	0.839	0.46
17_S	21_A	0.839	0.46
37_G	67_S	0.838	0.46
467_I	483_I	0.837	0.46
49_A	52_D	0.837	0.46
413_I	465_R	0.833	0.46
15_V	319_A	0.833	0.46
380_E	446_E	0.832	0.46
204_M	334_T	0.828	0.45
309_V	334_T	0.827	0.45
141_I	172_E	0.827	0.45
332_V	336_P	0.826	0.45
30_T	180_A	0.825	0.45
73_D	80_S	0.825	0.45
295_A	467_I	0.823	0.45
32_C	65_I	0.822	0.45
94_G	115_N	0.822	0.45
298_E	411_K	0.820	0.45
85_E	105_L	0.820	0.45
384_H	446_E	0.820	0.45
43_A	47_I	0.818	0.45
476_K	504_V	0.816	0.44
116_Y	152_G	0.814	0.44
22_V	49_A	0.807	0.44
509_L	513_D	0.806	0.44
309_V	359_M	0.804	0.43
212_A	242_I	0.803	0.43
375_Y	406_S	0.799	0.43
373_V	413_I	0.799	0.43
43_A	46_L	0.799	0.43
419_T	437_E	0.799	0.43
89_K	160_E	0.796	0.43
437_E	489_V	0.795	0.43
495_I	508_E	0.795	0.43
32_C	346_A	0.794	0.43
161_D	177_K	0.791	0.42
187_R	253_D	0.790	0.42
64_S	89_K	0.790	0.42
67_S	71_L	0.789	0.42
394_G	397_M	0.789	0.42
125_L	211_I	0.788	0.42
22_V	249_I	0.786	0.42
285_L	322_E	0.783	0.42
124_T	178_A	0.782	0.42
19_Q	23_N	0.782	0.42
24_Y	221_I	0.782	0.42
293_R	322_E	0.779	0.42
287_Q	469_E	0.779	0.42
189_T	200_E	0.777	0.41
118_Q	359_M	0.777	0.41
403_I	451_T	0.775	0.41
68_P	125_L	0.774	0.41
126_R	364_D	0.773	0.41
312_A	415_C	0.773	0.41
31_L	211_I	0.769	0.41
486_A	489_V	0.767	0.41
41_L	227_Q	0.767	0.41
146_D	174_L	0.766	0.41
41_L	97_G	0.766	0.41
154_L	203_V	0.763	0.40
229_M	252_V	0.761	0.40
230_V	276_D	0.758	0.40
118_Q	122_T	0.758	0.40
34_L	43_A	0.758	0.40
99_S	103_S	0.758	0.40
256_Q	260_Y	0.757	0.40
118_Q	207_D	0.754	0.40
307_V	330_L	0.752	0.39
149_Q	446_E	0.747	0.39
191_C	229_M	0.746	0.39
147_P	496_L	0.745	0.39
256_Q	259_L	0.745	0.39
470_R	489_V	0.741	0.39
299_M	487_P	0.739	0.38
115_N	397_M	0.738	0.38
333_E	363_F	0.737	0.38
68_P	121_L	0.737	0.38
73_D	76_D	0.736	0.38
126_R	130_A	0.735	0.38
33_V	65_I	0.734	0.38
389_V	451_T	0.734	0.38
203_V	362_Q	0.733	0.38
26_P	108_Q	0.730	0.38
36_A	377_S	0.730	0.38
337_I	357_L	0.729	0.38
158_T	161_D	0.726	0.37
459_E	477_E	0.726	0.37
66_I	128_A	0.725	0.37
44_T	51_A	0.725	0.37
48_T	256_Q	0.724	0.37
41_L	78_G	0.724	0.37
113_A	350_N	0.723	0.37
62_N	65_I	0.719	0.37
413_I	505_I	0.719	0.37
187_R	421_G	0.717	0.37
124_T	128_A	0.717	0.37
40_I	203_V	0.716	0.37
380_E	469_E	0.715	0.37
95_H	313_D	0.715	0.37
23_N	300_R	0.714	0.37
80_S	93_C	0.714	0.37
197_A	226_V	0.713	0.36
228_K	252_V	0.712	0.36
39_G	73_D	0.709	0.36
443_F	501_F	0.708	0.36
273_F	276_D	0.705	0.36
213_Q	361_S	0.704	0.36
285_L	289_K	0.702	0.36
164_K	167_E	0.702	0.36
313_D	379_A	0.700	0.35
75_A	92_L	0.699	0.35
153_K	158_T	0.697	0.35
313_D	316_G	0.697	0.35
230_V	233_A	0.697	0.35
113_A	214_A	0.695	0.35
492_Q	498_K	0.695	0.35
320_R	323_G	0.695	0.35
197_A	250_V	0.694	0.35
473_F	503_P	0.694	0.35
58_Q	61_R	0.691	0.35
312_A	343_Q	0.691	0.35
342_S	349_A	0.691	0.35
50_L	82_L	0.690	0.35
33_V	47_I	0.689	0.35
277_D	280_K	0.688	0.35
323_G	444_I	0.687	0.35
31_L	82_L	0.686	0.34
138_D	173_Y	0.686	0.34
95_H	397_M	0.685	0.34
191_C	235_L	0.685	0.34
205_Y	361_S	0.684	0.34
377_S	415_C	0.683	0.34
299_M	318_V	0.683	0.34
452_F	475_L	0.683	0.34
497_D	502_T	0.682	0.34
482_L	505_I	0.681	0.34
37_G	99_S	0.681	0.34
225_Q	240_V	0.680	0.34
15_V	500_D	0.680	0.34
21_A	251_V	0.679	0.34
315_I	467_I	0.679	0.34
122_T	181_P	0.678	0.34
23_N	53_K	0.678	0.34
390_H	451_T	0.674	0.34
274_T	352_N	0.674	0.34
324_C	327_D	0.674	0.34
504_V	509_L	0.672	0.33
34_L	97_G	0.670	0.33
68_P	359_M	0.668	0.33
446_E	492_Q	0.666	0.33
97_G	178_A	0.666	0.33
132_Q	137_S	0.665	0.33
106_A	113_A	0.664	0.33
168_F	175_Y	0.663	0.33
198_T	230_V	0.663	0.33
86_G	105_L	0.662	0.33
34_L	206_L	0.661	0.33
47_I	67_S	0.660	0.33
112_I	129_A	0.658	0.32
419_T	438_G	0.657	0.32
99_S	123_Q	0.656	0.32
471_A	485_I	0.656	0.32
73_D	77_R	0.656	0.32
52_D	84_Q	0.654	0.32
22_V	59_T	0.653	0.32
415_C	450_I	0.653	0.32
66_I	125_L	0.651	0.32
71_L	397_M	0.651	0.32
124_T	180_A	0.651	0.32
313_D	343_Q	0.650	0.32
42_E	67_S	0.650	0.32
242_I	247_V	0.648	0.32
471_A	489_V	0.647	0.32
46_L	215_V	0.647	0.32
189_T	201_D	0.646	0.32
389_V	392_F	0.645	0.32
386_N	393_N	0.645	0.32
445_R	510_K	0.642	0.31
507_P	510_K	0.639	0.31
92_L	121_L	0.637	0.31
30_T	66_I	0.637	0.31
477_E	506_S	0.637	0.31
330_L	341_T	0.637	0.31
229_M	337_I	0.637	0.31
134_G	178_A	0.636	0.31
319_A	404_D	0.636	0.31
287_Q	417_T	0.635	0.31
132_Q	135_I	0.634	0.31
182_D	511_L	0.634	0.31
257_T	261_G	0.633	0.31
353_T	356_I	0.632	0.31
485_I	511_L	0.631	0.31
15_V	273_F	0.629	0.30
304_V	365_F	0.628	0.30
443_F	466_Y	0.628	0.30
322_E	352_N	0.628	0.30
105_L	108_Q	0.625	0.30
76_D	101_R	0.625	0.30
380_E	482_L	0.625	0.30
25_I	411_K	0.624	0.30
28_E	31_L	0.624	0.30
483_I	506_S	0.624	0.30
50_L	250_V	0.623	0.30
458_L	476_K	0.623	0.30
72_G	371_L	0.623	0.30
342_S	404_D	0.622	0.30
39_G	94_G	0.621	0.30
166_V	169_D	0.621	0.30
185_F	413_I	0.621	0.30
31_L	62_N	0.621	0.30
483_I	489_V	0.620	0.30
97_G	395_K	0.620	0.30
496_L	503_P	0.620	0.30
207_D	359_M	0.618	0.30
208_A	242_I	0.614	0.29
191_C	197_A	0.614	0.29
191_C	226_V	0.612	0.29
95_H	379_A	0.612	0.29
20_E	46_L	0.609	0.29
112_I	158_T	0.609	0.29
129_A	214_A	0.608	0.29
26_P	183_I	0.607	0.29
41_L	204_M	0.606	0.29
120_V	387_V	0.605	0.29
67_S	102_I	0.603	0.29
118_Q	342_S	0.602	0.29
42_E	334_T	0.602	0.29
80_S	345_I	0.602	0.29
152_G	162_L	0.601	0.29
316_G	350_N	0.601	0.29
489_V	498_K	0.600	0.28
16_L	20_E	0.600	0.28
34_L	211_I	0.597	0.28
418_L	499_M	0.597	0.28
485_I	505_I	0.597	0.28
288_R	330_L	0.597	0.28
242_I	281_L	0.597	0.28
452_F	457_A	0.597	0.28
88_V	122_T	0.596	0.28
48_T	81_P	0.595	0.28
30_T	64_S	0.595	0.28
130_A	316_G	0.594	0.28
67_S	79_I	0.593	0.28
81_P	304_V	0.593	0.28
212_A	299_M	0.592	0.28
145_V	184_A	0.589	0.28
490_D	495_I	0.589	0.28
76_D	263_A	0.588	0.28
506_S	511_L	0.588	0.28
43_A	445_R	0.587	0.28
37_G	71_L	0.586	0.28
359_M	404_D	0.586	0.28
58_Q	446_E	0.585	0.28
384_H	445_R	0.585	0.28
91_A	106_A	0.585	0.28
161_D	165_L	0.584	0.27
137_S	179_I	0.584	0.27
213_Q	336_P	0.583	0.27
302_G	411_K	0.583	0.27
97_G	209_L	0.583	0.27
231_K	277_D	0.580	0.27
71_L	118_Q	0.580	0.27
269_I	342_S	0.580	0.27
97_G	207_D	0.579	0.27
110_K	302_G	0.579	0.27
458_L	478_D	0.579	0.27
153_K	156_E	0.578	0.27
37_G	72_G	0.577	0.27
149_Q	453_S	0.577	0.27
34_L	350_N	0.577	0.27
345_I	349_A	0.574	0.27
91_A	111_I	0.574	0.27
21_A	249_I	0.573	0.27
46_L	223_M	0.573	0.27
306_N	363_F	0.572	0.27
506_S	510_K	0.571	0.27
67_S	345_I	0.570	0.27
177_K	289_K	0.570	0.27
187_R	227_Q	0.569	0.27
25_I	87_L	0.569	0.27
19_Q	49_A	0.568	0.26
161_D	451_T	0.566	0.26
399_T	403_I	0.566	0.26
47_I	71_L	0.566	0.26
301_K	327_D	0.565	0.26
146_D	165_L	0.564	0.26
251_V	358_D	0.564	0.26
116_Y	125_L	0.563	0.26
88_V	92_L	0.563	0.26
120_V	376_L	0.562	0.26
25_I	212_A	0.561	0.26
125_L	179_I	0.561	0.26
191_C	224_M	0.561	0.26
128_A	181_P	0.560	0.26
97_G	397_M	0.560	0.26
39_G	76_D	0.559	0.26
53_K	60_P	0.558	0.26
47_I	82_L	0.557	0.26
453_S	456_I	0.557	0.26
202_E	336_P	0.556	0.26
142_G	332_V	0.556	0.26
439_R	455_K	0.556	0.26
381_V	393_N	0.556	0.26
172_E	193_S	0.555	0.26
371_L	420_A	0.554	0.26
31_L	384_H	0.554	0.26
41_L	349_A	0.553	0.26
316_G	380_E	0.553	0.26
495_I	509_L	0.553	0.26
305_G	373_V	0.552	0.25
44_T	118_Q	0.552	0.25
319_A	324_C	0.551	0.25
379_A	393_N	0.549	0.25
31_L	446_E	0.548	0.25
31_L	46_L	0.548	0.25
475_L	480_L	0.548	0.25
379_A	451_T	0.547	0.25
138_D	216_H	0.547	0.25
312_A	334_T	0.546	0.25
43_A	317_L	0.546	0.25
125_L	361_S	0.546	0.25
19_Q	169_D	0.546	0.25
265_V	270_S	0.545	0.25
403_I	407_A	0.545	0.25
443_F	475_L	0.544	0.25
439_R	498_K	0.544	0.25
299_M	315_I	0.543	0.25
496_L	504_V	0.543	0.25
99_S	334_T	0.542	0.25
185_F	215_V	0.541	0.25
311_I	314_G	0.541	0.25
155_N	158_T	0.540	0.25
164_K	168_F	0.539	0.25
17_S	53_K	0.538	0.25
294_R	472_V	0.538	0.25
33_V	82_L	0.537	0.25
193_S	495_I	0.537	0.25
125_L	181_P	0.537	0.25
230_V	234_T	0.536	0.24
193_S	233_A	0.536	0.24
458_L	477_E	0.536	0.24
364_D	469_E	0.536	0.24
168_F	446_E	0.535	0.24
83_A	94_G	0.534	0.24
52_D	459_E	0.533	0.24
280_K	495_I	0.533	0.24
198_T	414_F	0.533	0.24
60_P	496_L	0.531	0.24
39_G	349_A	0.529	0.24
285_L	293_R	0.529	0.24
190_T	199_F	0.529	0.24
286_N	289_K	0.526	0.24
458_L	495_I	0.526	0.24
383_Q	446_E	0.525	0.24
33_V	43_A	0.525	0.24
133_P	237_P	0.525	0.24
476_K	483_I	0.525	0.24
30_T	179_I	0.525	0.24
35_G	334_T	0.525	0.24
186_I	194_E	0.524	0.24
25_I	77_R	0.524	0.24
53_K	59_T	0.524	0.24
62_N	510_K	0.523	0.24
375_Y	412_I	0.523	0.24
96_W	206_L	0.523	0.24
115_N	348_G	0.522	0.24
478_D	495_I	0.521	0.24
36_A	42_E	0.521	0.24
146_D	172_E	0.521	0.24
35_G	473_F	0.521	0.24
227_Q	334_T	0.520	0.24
46_L	184_A	0.520	0.24
17_S	22_V	0.519	0.23
17_S	513_D	0.519	0.23
158_T	237_P	0.519	0.23
60_P	488_G	0.518	0.23
177_K	478_D	0.518	0.23
185_F	316_G	0.517	0.23
140_G	339_G	0.517	0.23
332_V	375_Y	0.516	0.23
182_D	242_I	0.516	0.23
380_E	417_T	0.516	0.23
276_D	491_L	0.515	0.23
271_G	352_N	0.515	0.23
35_G	63_L	0.515	0.23
490_D	506_S	0.515	0.23
328_F	411_K	0.514	0.23
50_L	327_D	0.514	0.23
229_M	273_F	0.514	0.23
67_S	99_S	0.514	0.23
203_V	349_A	0.513	0.23
92_L	214_A	0.513	0.23
295_A	415_C	0.512	0.23
122_T	207_D	0.512	0.23
105_L	296_L	0.512	0.23
22_V	455_K	0.511	0.23
128_A	214_A	0.511	0.23
312_A	378_F	0.510	0.23
204_M	371_L	0.510	0.23
82_L	344_G	0.510	0.23
21_A	50_L	0.509	0.23
485_I	494_D	0.509	0.23
197_A	221_I	0.508	0.23
177_K	240_V	0.508	0.23
95_H	309_V	0.508	0.23
121_L	346_A	0.508	0.23
411_K	477_E	0.507	0.23
306_N	377_S	0.506	0.23
36_A	44_T	0.505	0.23
319_A	465_R	0.505	0.23
260_Y	346_A	0.504	0.23
37_G	343_Q	0.504	0.23
17_S	384_H	0.503	0.23
40_I	208_A	0.503	0.23
270_S	406_S	0.503	0.23
203_V	311_I	0.502	0.23
41_L	99_S	0.502	0.23
164_K	177_K	0.502	0.23
97_G	120_V	0.501	0.22
88_V	282_S	0.501	0.22
92_L	158_T	0.501	0.22
198_T	250_V	0.501	0.22
311_I	415_C	0.501	0.22
72_G	120_V	0.501	0.22
175_Y	309_V	0.501	0.22
46_L	251_V	0.500	0.22

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2ahuA	3	0.9699	100	0.307	Contact Map
3k6mA	2	0.8399	100	0.449	Contact Map
4kgbA	2	0.8418	100	0.45	Contact Map
2hj0A	2	0.8023	100	0.615	Contact Map
3qliA	2	0.7646	100	0.62	Contact Map
4eu9A	2	0.8192	100	0.621	Contact Map
2nvvA	2	0.7721	100	0.621	Contact Map
1xr4A	2	0.8136	100	0.623	Contact Map
2g39A	2	0.7891	100	0.624	Contact Map
3gk7A	2	0.7627	100	0.632	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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