EPTB - ECOLI - GREMLIN Contacts

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EPTB - Phosphoethanolamine transferase EptB

UniProt:	P37661	Sequences: MRYIKSITQQKLSFLLAIYIGLFMNGAVFYRRFGSYAHDFTVWKGISAVVELAATVLVTFFLLRLLSLFGRRSWRILASLVVLFSAGASYYMTFLNVVIGYGIIASVMTTDIDLSKEVVGLNFILWLIAVSALPLILIWNNRCRYTLLRQLRTPGQRIRSLAVVVLAGIMVWAPIRLLDIQQKKVERATGVDLPSYGGVVANSYLPSNWLSALGLYAWARVDESSDNNSLLNPAKKFTYQAPQNVDDTYVVFIIGETTRWDHMGIFGYERNTTPKLAQEKNLAAFRGYSCDTATKLSLRCMFVRQGGAEDNPQRTLKEQNIFAVLKQLGFSSDLYAMQSEMWFYSNTMADNIAYREQIGAEPRNRGKPVDDMLLVDEMQQSLGRNPDGKHLIILHTKGSHFNYTQRYPRSFAQWKPECIGVDSGCTKAQMINSYDNSVTYVDHFISSVIDQVRDKKAIVFYAADHGESINEREHLHGTPRELAPPEQFRVPMMVWMSDKYLENPANAQAFAQLKKEADMKVPRRHVELYDTIMGCLGYTSPDGGINENNNWCHIPQAKEAAAN	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG12267
Length:	563 (501)
Sequences:	5455 (4658)
Seq/√Len:	208.1

ECOLI - EPTB EPTA EPTC YHBX OPGE YEJM YJGX
BACSU - YQGS LTAS1 LTAS2 YVGJ

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
275_K	446_S	6.444	1.00
326_K	355_R	4.808	1.00
534_G	548_N	4.763	1.00
383_G	455_K	4.210	1.00
275_K	278_Q	4.184	1.00
379_Q	451_Q	3.922	1.00
271_N	277_A	3.585	1.00
331_S	388_G	3.512	1.00
446_S	450_D	3.439	1.00
531_T	550_N	3.435	1.00
523_R	549_N	3.185	1.00
253_I	461_Y	3.166	1.00
250_V	325_L	3.049	1.00
450_D	453_R	3.030	1.00
249_Y	457_A	3.024	1.00
138_I	142_R	3.001	1.00
251_V	459_V	2.976	1.00
255_G	258_T	2.897	1.00
250_V	536_L	2.875	1.00
264_G	273_T	2.869	1.00
281_N	453_R	2.822	1.00
248_T	456_K	2.767	1.00
325_L	536_L	2.557	1.00
218_W	221_V	2.413	1.00
452_V	459_V	2.409	1.00
449_I	459_V	2.363	1.00
139_W	143_C	2.320	1.00
249_Y	390_H	2.300	1.00
266_F	284_A	2.277	1.00
251_V	457_A	2.244	1.00
303_V	320_N	2.237	1.00
273_T	277_A	2.227	1.00
372_M	447_S	2.220	1.00
377_E	380_Q	2.208	1.00
447_S	450_D	2.199	1.00
450_D	454_D	2.136	1.00
252_F	391_L	2.103	1.00
408_P	440_Y	2.061	1.00
25_N	29_F	2.057	1.00
246_D	456_K	2.039	1.00
359_G	362_P	2.013	1.00
458_I	494_V	2.003	1.00
378_M	394_L	1.995	1.00
345_S	349_A	1.991	1.00
253_I	445_I	1.977	1.00
301_M	462_A	1.950	1.00
252_F	460_F	1.917	1.00
412_A	415_K	1.909	1.00
335_Y	381_S	1.898	1.00
399_S	437_S	1.891	1.00
211_S	215_L	1.842	1.00
274_P	442_D	1.822	1.00
156_Q	160_S	1.816	1.00
294_T	395_H	1.796	1.00
128_I	132_A	1.792	1.00
208_N	211_S	1.790	1.00
379_Q	455_K	1.784	1.00
372_M	440_Y	1.780	1.00
379_Q	383_G	1.767	1.00
25_N	28_V	1.763	1.00
45_G	49_V	1.745	1.00
375_V	379_Q	1.731	1.00
193_L	196_Y	1.724	1.00
400_H	464_D	1.722	1.00
157_R	160_S	1.698	1.00
226_D	229_S	1.693	1.00
258_T	438_V	1.680	1.00
413_Q	439_T	1.680	1.00
460_F	494_V	1.677	1.00
462_A	525_H	1.675	1.00
88_A	98_V	1.672	1.00
264_G	271_N	1.662	1.00
234_A	237_F	1.661	1.00
439_T	443_H	1.660	1.00
443_H	447_S	1.647	1.00
346_N	350_D	1.647	1.00
204_Y	208_N	1.624	1.00
226_D	231_L	1.615	1.00
194_P	198_G	1.591	1.00
255_G	461_Y	1.589	1.00
258_T	441_V	1.588	1.00
448_V	459_V	1.574	1.00
451_Q	454_D	1.573	1.00
254_I	298_L	1.573	1.00
492_M	528_L	1.573	1.00
264_G	277_A	1.557	1.00
140_N	144_R	1.556	1.00
414_W	417_E	1.555	1.00
286_R	506_N	1.550	1.00
171_V	175_I	1.550	1.00
255_G	441_V	1.545	1.00
340_E	346_N	1.540	1.00
374_L	394_L	1.537	1.00
262_H	435_D	1.513	1.00
218_W	222_D	1.506	1.00
282_L	495_W	1.502	1.00
463_A	490_V	1.501	1.00
375_V	396_T	1.497	1.00
248_T	458_I	1.486	1.00
443_H	446_S	1.484	1.00
218_W	223_E	1.482	1.00
333_D	390_H	1.477	1.00
208_N	212_A	1.475	1.00
278_Q	281_N	1.468	1.00
451_Q	455_K	1.462	1.00
333_D	392_I	1.461	1.00
254_I	462_A	1.460	1.00
158_I	161_L	1.454	1.00
174_P	178_L	1.451	1.00
204_Y	209_W	1.438	1.00
233_P	236_K	1.434	1.00
335_Y	392_I	1.424	1.00
173_A	177_L	1.422	1.00
411_F	443_H	1.420	1.00
321_I	532_I	1.419	1.00
250_V	458_I	1.414	1.00
209_W	212_A	1.413	1.00
192_D	195_S	1.391	1.00
232_N	235_K	1.390	1.00
156_Q	159_R	1.382	1.00
276_L	445_I	1.377	1.00
344_Y	347_T	1.373	1.00
485_P	489_R	1.367	1.00
375_V	448_V	1.367	1.00
304_R	530_D	1.365	1.00
324_V	533_M	1.358	1.00
273_T	276_L	1.350	1.00
200_V	203_S	1.348	1.00
447_S	451_Q	1.341	1.00
412_A	417_E	1.340	1.00
172_W	176_R	1.340	1.00
496_M	500_Y	1.336	1.00
449_I	453_R	1.332	1.00
227_N	230_L	1.332	1.00
192_D	196_Y	1.322	1.00
46_I	49_V	1.316	1.00
414_W	418_C	1.312	1.00
409_R	412_A	1.310	1.00
341_M	346_N	1.306	1.00
444_F	448_V	1.300	1.00
336_A	345_S	1.300	1.00
224_S	227_N	1.296	1.00
230_L	233_P	1.291	1.00
222_D	225_S	1.291	1.00
168_G	172_W	1.286	1.00
115_S	118_V	1.283	1.00
47_S	51_E	1.283	1.00
227_N	231_L	1.282	1.00
270_R	435_D	1.279	1.00
502_E	506_N	1.278	1.00
260_W	266_F	1.276	1.00
252_F	301_M	1.276	1.00
334_L	349_A	1.276	1.00
399_S	438_V	1.274	1.00
255_G	445_I	1.267	1.00
503_N	506_N	1.261	1.00
250_V	391_L	1.260	1.00
444_F	447_S	1.251	1.00
262_H	438_V	1.248	1.00
403_Y	467_E	1.247	1.00
334_L	395_H	1.234	1.00
183_K	186_E	1.228	1.00
21_G	24_M	1.226	1.00
285_F	492_M	1.225	1.00
177_L	181_Q	1.223	1.00
287_G	522_P	1.212	1.00
230_L	234_A	1.212	1.00
220_R	223_E	1.208	1.00
399_S	441_V	1.208	1.00
278_Q	446_S	1.206	1.00
533_M	538_Y	1.202	1.00
275_K	442_D	1.196	1.00
219_A	223_E	1.195	1.00
268_Y	435_D	1.195	1.00
502_E	505_A	1.193	1.00
195_S	204_Y	1.192	1.00
205_L	208_N	1.189	1.00
112_I	116_K	1.184	1.00
378_M	382_L	1.181	1.00
208_N	213_L	1.173	1.00
226_D	230_L	1.170	1.00
383_G	451_Q	1.169	1.00
227_N	234_A	1.168	1.00
62_L	66_L	1.167	1.00
294_T	400_H	1.163	1.00
258_T	262_H	1.163	1.00
193_L	200_V	1.162	1.00
342_W	345_S	1.153	1.00
258_T	263_M	1.151	1.00
48_A	51_E	1.149	1.00
234_A	238_T	1.148	1.00
51_E	55_T	1.147	1.00
302_F	391_L	1.144	1.00
192_D	198_G	1.142	1.00
408_P	411_F	1.141	1.00
22_L	25_N	1.134	1.00
301_M	528_L	1.131	1.00
290_C	300_C	1.129	1.00
250_V	460_F	1.127	1.00
49_V	52_L	1.126	1.00
344_Y	349_A	1.125	1.00
275_K	449_I	1.125	1.00
260_W	489_R	1.125	1.00
165_V	169_I	1.125	1.00
496_M	499_K	1.118	1.00
412_A	416_P	1.118	1.00
212_A	215_L	1.117	1.00
196_Y	199_V	1.116	1.00
458_I	496_M	1.116	1.00
229_S	237_F	1.115	1.00
206_P	212_A	1.106	1.00
48_A	52_L	1.103	1.00
340_E	344_Y	1.099	1.00
328_L	538_Y	1.096	1.00
340_E	359_G	1.095	1.00
333_D	381_S	1.095	1.00
287_G	489_R	1.094	1.00
231_L	235_K	1.092	1.00
203_S	207_S	1.091	1.00
275_K	443_H	1.090	1.00
272_T	277_A	1.089	1.00
177_L	180_I	1.088	1.00
254_I	393_I	1.087	1.00
223_E	226_D	1.084	1.00
251_V	390_H	1.079	1.00
139_W	142_R	1.076	1.00
136_I	140_N	1.075	1.00
258_T	273_T	1.074	1.00
407_Y	436_N	1.070	1.00
460_F	532_I	1.068	1.00
254_I	301_M	1.066	1.00
500_Y	503_N	1.065	1.00
224_S	231_L	1.060	1.00
256_E	464_D	1.059	1.00
382_L	452_V	1.057	1.00
252_F	393_I	1.057	1.00
203_S	212_A	1.056	1.00
458_I	532_I	1.056	1.00
247_D	328_L	1.055	1.00
58_V	62_L	1.053	1.00
376_D	447_S	1.047	1.00
25_N	30_Y	1.045	1.00
195_S	199_V	1.043	1.00
55_T	62_L	1.041	1.00
427_K	432_N	1.040	1.00
259_R	466_G	1.033	1.00
394_L	448_V	1.032	1.00
368_P	397_K	1.032	1.00
209_W	214_G	1.030	1.00
377_E	381_S	1.029	1.00
114_L	117_E	1.023	1.00
331_S	356_E	1.021	1.00
203_S	206_P	1.012	1.00
203_S	208_N	1.012	1.00
114_L	118_V	1.011	1.00
275_K	450_D	1.008	1.00
233_P	237_F	1.005	1.00
346_N	349_A	1.004	1.00
191_V	194_P	1.002	1.00
283_A	550_N	1.000	1.00
208_N	215_L	0.998	1.00
167_A	171_V	0.998	1.00
204_Y	213_L	0.995	1.00
219_A	222_D	0.995	1.00
51_E	54_A	0.993	1.00
201_A	204_Y	0.988	1.00
220_R	224_S	0.978	1.00
256_E	400_H	0.977	1.00
67_S	70_G	0.977	1.00
23_F	30_Y	0.973	1.00
228_N	232_N	0.972	1.00
212_A	216_Y	0.972	1.00
195_S	198_G	0.970	1.00
21_G	25_N	0.969	1.00
462_A	528_L	0.961	1.00
175_I	179_D	0.959	1.00
382_L	392_I	0.958	1.00
396_T	441_V	0.953	0.99
169_I	173_A	0.951	0.99
53_A	57_L	0.945	0.99
371_D	375_V	0.940	0.99
228_N	234_A	0.939	0.99
50_V	55_T	0.939	0.99
449_I	461_Y	0.937	0.99
258_T	276_L	0.937	0.99
42_V	47_S	0.936	0.99
255_G	375_V	0.936	0.99
279_E	282_L	0.936	0.99
376_D	451_Q	0.935	0.99
325_L	391_L	0.935	0.99
79_S	83_L	0.935	0.99
173_A	176_R	0.927	0.99
202_N	207_S	0.921	0.99
17_A	25_N	0.921	0.99
330_F	389_K	0.920	0.99
329_G	389_K	0.917	0.99
274_P	277_A	0.915	0.99
250_V	330_F	0.914	0.99
207_S	212_A	0.912	0.99
398_G	440_Y	0.911	0.99
202_N	205_L	0.910	0.99
413_Q	416_P	0.910	0.99
26_G	30_Y	0.910	0.99
319_Q	327_Q	0.909	0.99
342_W	349_A	0.908	0.99
477_G	480_R	0.906	0.99
231_L	234_A	0.905	0.99
325_L	533_M	0.905	0.99
164_V	167_A	0.901	0.99
294_T	464_D	0.901	0.99
174_P	177_L	0.899	0.99
31_R	34_G	0.899	0.99
194_P	197_G	0.898	0.99
60_F	66_L	0.898	0.99
530_D	546_N	0.897	0.99
193_L	198_G	0.897	0.99
174_P	180_I	0.897	0.99
210_L	214_G	0.897	0.99
349_A	354_Y	0.895	0.99
333_D	356_E	0.894	0.99
304_R	318_E	0.893	0.99
175_I	181_Q	0.891	0.99
373_L	376_D	0.887	0.99
252_F	528_L	0.887	0.99
19_Y	25_N	0.885	0.99
23_F	26_G	0.882	0.99
179_D	182_Q	0.882	0.99
219_A	226_D	0.879	0.99
180_I	183_K	0.877	0.99
254_I	395_H	0.876	0.99
204_Y	207_S	0.875	0.99
248_T	389_K	0.874	0.99
194_P	204_Y	0.872	0.99
272_T	435_D	0.872	0.99
335_Y	374_L	0.871	0.99
282_L	493_M	0.871	0.99
228_N	231_L	0.870	0.99
28_V	32_R	0.868	0.99
252_F	462_A	0.867	0.99
375_V	441_V	0.862	0.99
21_G	29_F	0.862	0.99
207_S	210_L	0.860	0.99
298_L	345_S	0.858	0.99
29_F	32_R	0.857	0.99
426_T	429_Q	0.857	0.99
219_A	224_S	0.855	0.99
404_T	433_S	0.855	0.99
294_T	298_L	0.854	0.99
378_M	392_I	0.851	0.99
172_W	182_Q	0.850	0.99
53_A	63_L	0.850	0.99
229_S	234_A	0.846	0.99
58_V	61_F	0.841	0.99
46_I	50_V	0.841	0.99
272_T	276_L	0.840	0.99
276_L	438_V	0.839	0.99
61_F	64_R	0.837	0.99
181_Q	184_K	0.837	0.99
222_D	226_D	0.836	0.99
354_Y	393_I	0.833	0.99
270_R	274_P	0.831	0.99
158_I	162_A	0.830	0.99
372_M	443_H	0.828	0.99
209_W	215_L	0.827	0.99
210_L	213_L	0.826	0.99
204_Y	212_A	0.824	0.99
322_F	354_Y	0.824	0.99
475_L	478_T	0.823	0.99
175_I	178_L	0.822	0.98
253_I	375_V	0.819	0.98
134_P	138_I	0.819	0.98
54_A	62_L	0.817	0.98
148_L	151_L	0.809	0.98
303_V	348_M	0.808	0.98
529_Y	533_M	0.805	0.98
44_K	47_S	0.804	0.98
157_R	161_L	0.801	0.98
60_F	63_L	0.800	0.98
398_G	437_S	0.799	0.98
347_T	350_D	0.798	0.98
61_F	65_L	0.796	0.98
176_R	180_I	0.796	0.98
370_D	373_L	0.793	0.98
220_R	225_S	0.792	0.98
251_V	382_L	0.792	0.98
194_P	200_V	0.790	0.98
462_A	490_V	0.789	0.98
49_V	59_T	0.789	0.98
141_N	144_R	0.788	0.98
326_K	332_S	0.787	0.98
160_S	164_V	0.787	0.98
249_Y	458_I	0.784	0.98
224_S	228_N	0.783	0.98
223_E	227_N	0.781	0.98
339_S	342_W	0.779	0.98
400_H	465_H	0.776	0.98
49_V	53_A	0.773	0.98
331_S	355_R	0.773	0.98
467_E	470_N	0.772	0.98
330_F	536_L	0.771	0.98
288_Y	489_R	0.767	0.98
51_E	56_V	0.765	0.98
172_W	180_I	0.762	0.98
461_Y	493_M	0.761	0.98
445_I	461_Y	0.761	0.98
54_A	58_V	0.759	0.97
467_E	487_Q	0.758	0.97
29_F	33_F	0.757	0.97
479_P	484_P	0.757	0.97
250_V	532_I	0.757	0.97
268_Y	272_T	0.756	0.97
169_I	172_W	0.756	0.97
33_F	36_Y	0.755	0.97
163_V	167_A	0.755	0.97
325_L	328_L	0.753	0.97
252_F	321_I	0.751	0.97
396_T	444_F	0.751	0.97
175_I	180_I	0.751	0.97
271_N	439_T	0.749	0.97
241_A	550_N	0.749	0.97
338_Q	397_K	0.748	0.97
218_W	226_D	0.747	0.97
25_N	34_G	0.746	0.97
17_A	21_G	0.746	0.97
363_R	377_E	0.745	0.97
159_R	162_A	0.744	0.97
19_Y	23_F	0.744	0.97
176_R	183_K	0.743	0.97
24_M	28_V	0.742	0.97
42_V	45_G	0.741	0.97
335_Y	358_I	0.740	0.97
51_E	60_F	0.739	0.97
125_L	129_A	0.739	0.97
258_T	399_S	0.738	0.97
43_W	50_V	0.737	0.97
43_W	47_S	0.737	0.97
159_R	170_M	0.735	0.97
59_T	65_L	0.735	0.97
141_N	145_Y	0.734	0.97
43_W	46_I	0.733	0.97
45_G	55_T	0.732	0.97
31_R	35_S	0.731	0.97
432_N	436_N	0.731	0.97
208_N	216_Y	0.729	0.97
441_V	444_F	0.728	0.97
225_S	233_P	0.728	0.97
130_V	134_P	0.726	0.97
52_L	56_V	0.726	0.97
321_I	529_Y	0.725	0.97
164_V	168_G	0.723	0.97
415_K	418_C	0.723	0.97
229_S	232_N	0.723	0.97
50_V	54_A	0.723	0.97
25_N	33_F	0.722	0.97
344_Y	351_N	0.721	0.97
25_N	31_R	0.719	0.97
501_L	504_P	0.713	0.96
46_I	52_L	0.713	0.96
445_I	459_V	0.710	0.96
171_V	174_P	0.710	0.96
176_R	181_Q	0.710	0.96
476_H	479_P	0.710	0.96
230_L	237_F	0.709	0.96
253_I	459_V	0.709	0.96
324_V	327_Q	0.708	0.96
56_V	63_L	0.705	0.96
52_L	60_F	0.705	0.96
26_G	29_F	0.705	0.96
263_M	273_T	0.704	0.96
202_N	206_P	0.704	0.96
414_W	432_N	0.704	0.96
322_F	332_S	0.702	0.96
211_S	214_G	0.701	0.96
138_I	141_N	0.700	0.96
132_A	136_I	0.699	0.96
361_E	364_N	0.698	0.96
440_Y	443_H	0.697	0.96
43_W	51_E	0.697	0.96
251_V	448_V	0.696	0.96
434_Y	438_V	0.695	0.96
51_E	63_L	0.694	0.96
83_L	131_S	0.691	0.96
112_I	119_V	0.690	0.96
155_G	159_R	0.690	0.96
276_L	493_M	0.690	0.96
88_A	99_I	0.686	0.95
380_Q	451_Q	0.685	0.95
144_R	147_L	0.685	0.95
20_I	25_N	0.684	0.95
295_K	343_F	0.684	0.95
376_D	379_Q	0.682	0.95
131_S	135_L	0.681	0.95
380_Q	383_G	0.679	0.95
337_M	397_K	0.679	0.95
91_Y	100_G	0.677	0.95
247_D	389_K	0.675	0.95
83_L	87_G	0.675	0.95
337_M	374_L	0.675	0.95
258_T	461_Y	0.675	0.95
206_P	209_W	0.672	0.95
273_T	442_D	0.672	0.95
126_W	130_V	0.671	0.95
191_V	195_S	0.669	0.95
349_A	352_I	0.669	0.95
358_I	381_S	0.668	0.95
48_A	53_A	0.668	0.95
30_Y	35_S	0.667	0.95
167_A	170_M	0.667	0.95
546_N	549_N	0.663	0.95
373_L	377_E	0.661	0.94
261_D	486_E	0.660	0.94
441_V	445_I	0.660	0.94
436_N	439_T	0.659	0.94
50_V	61_F	0.659	0.94
172_W	181_Q	0.657	0.94
224_S	230_L	0.656	0.94
113_D	117_E	0.656	0.94
282_L	286_R	0.654	0.94
468_S	487_Q	0.654	0.94
160_S	175_I	0.653	0.94
64_R	67_S	0.651	0.94
414_W	439_T	0.651	0.94
59_T	64_R	0.650	0.94
204_Y	214_G	0.649	0.94
461_Y	495_W	0.649	0.94
285_F	288_Y	0.649	0.94
47_S	50_V	0.648	0.94
500_Y	504_P	0.648	0.94
30_Y	33_F	0.648	0.94
176_R	179_D	0.647	0.94
201_A	212_A	0.646	0.94
162_A	166_L	0.646	0.94
302_F	393_I	0.644	0.94
235_K	238_T	0.644	0.94
476_H	480_R	0.642	0.94
31_R	37_A	0.636	0.93
232_N	236_K	0.636	0.93
338_Q	395_H	0.636	0.93
195_S	200_V	0.636	0.93
103_I	106_S	0.635	0.93
248_T	330_F	0.634	0.93
229_S	233_P	0.634	0.93
140_N	143_C	0.632	0.93
485_P	488_F	0.631	0.93
308_A	311_N	0.631	0.93
79_S	82_V	0.631	0.93
337_M	369_V	0.629	0.93
257_T	465_H	0.626	0.93
213_L	216_Y	0.625	0.93
18_I	22_L	0.625	0.93
492_M	549_N	0.624	0.93
112_I	118_V	0.622	0.92
239_Y	242_P	0.622	0.92
143_C	146_T	0.621	0.92
167_A	172_W	0.619	0.92
174_P	179_D	0.619	0.92
337_M	367_K	0.617	0.92
271_N	274_P	0.616	0.92
343_F	346_N	0.616	0.92
217_A	221_V	0.615	0.92
458_I	500_Y	0.615	0.92
378_M	448_V	0.615	0.92
209_W	216_Y	0.614	0.92
63_L	66_L	0.614	0.92
232_N	237_F	0.614	0.92
336_A	395_H	0.614	0.92
14_F	18_I	0.613	0.92
173_A	181_Q	0.613	0.92
300_C	525_H	0.611	0.92
206_P	210_L	0.611	0.92
345_S	348_M	0.611	0.92
46_I	51_E	0.610	0.92
49_V	54_A	0.610	0.92
16_L	20_I	0.607	0.92
330_F	458_I	0.605	0.91
332_S	355_R	0.605	0.91
298_L	336_A	0.605	0.91
148_L	152_R	0.604	0.91
414_W	436_N	0.603	0.91
87_G	99_I	0.603	0.91
158_I	169_I	0.602	0.91
475_L	479_P	0.601	0.91
322_F	391_L	0.600	0.91
209_W	213_L	0.599	0.91
375_V	444_F	0.598	0.91
48_A	61_F	0.596	0.91
411_F	440_Y	0.596	0.91
178_L	181_Q	0.594	0.91
178_L	182_Q	0.593	0.91
294_T	465_H	0.593	0.91
112_I	115_S	0.593	0.91
157_R	164_V	0.593	0.91
56_V	59_T	0.591	0.90
206_P	216_Y	0.591	0.90
219_A	231_L	0.591	0.90
55_T	60_F	0.591	0.90
55_T	59_T	0.590	0.90
249_Y	455_K	0.589	0.90
247_D	458_I	0.589	0.90
226_D	234_A	0.588	0.90
116_K	119_V	0.587	0.90
131_S	134_P	0.586	0.90
172_W	175_I	0.585	0.90
161_L	165_V	0.584	0.90
167_A	177_L	0.583	0.90
345_S	395_H	0.583	0.90
200_V	204_Y	0.583	0.90
256_E	396_T	0.582	0.90
260_W	284_A	0.581	0.90
297_S	462_A	0.579	0.90
222_D	227_N	0.579	0.90
22_L	27_A	0.578	0.89
192_D	199_V	0.576	0.89
51_E	62_L	0.576	0.89
126_W	134_P	0.575	0.89
176_R	182_Q	0.575	0.89
161_L	180_I	0.575	0.89
124_I	128_I	0.575	0.89
160_S	176_R	0.575	0.89
331_S	532_I	0.572	0.89
356_E	359_G	0.572	0.89
356_E	360_A	0.571	0.89
264_G	272_T	0.571	0.89
263_M	266_F	0.571	0.89
478_T	484_P	0.570	0.89
168_G	176_R	0.570	0.89
57_L	69_F	0.569	0.89
348_M	351_N	0.569	0.89
58_V	64_R	0.568	0.89
323_A	327_Q	0.568	0.89
160_S	177_L	0.568	0.89
45_G	48_A	0.568	0.89
257_T	463_A	0.568	0.89
484_P	487_Q	0.567	0.89
344_Y	348_M	0.565	0.88
63_L	67_S	0.565	0.88
45_G	52_L	0.565	0.88
219_A	230_L	0.565	0.88
230_L	238_T	0.565	0.88
228_N	236_K	0.565	0.88
491_P	494_V	0.564	0.88
226_D	237_F	0.564	0.88
38_H	41_T	0.564	0.88
160_S	172_W	0.564	0.88
173_A	180_I	0.562	0.88
61_F	66_L	0.562	0.88
490_V	525_H	0.561	0.88
226_D	235_K	0.561	0.88
299_R	305_Q	0.560	0.88
492_M	523_R	0.560	0.88
201_A	205_L	0.560	0.88
273_T	438_V	0.560	0.88
217_A	225_S	0.560	0.88
18_I	25_N	0.559	0.88
52_L	66_L	0.559	0.88
205_L	212_A	0.558	0.88
307_G	310_D	0.558	0.88
257_T	464_D	0.557	0.88
43_W	53_A	0.555	0.87
166_L	173_A	0.555	0.87
175_I	182_Q	0.554	0.87
338_Q	342_W	0.554	0.87
407_Y	437_S	0.551	0.87
202_N	208_N	0.550	0.87
249_Y	389_K	0.550	0.87
346_N	351_N	0.550	0.87
282_L	285_F	0.549	0.87
256_E	399_S	0.548	0.87
255_G	399_S	0.547	0.87
93_T	127_L	0.547	0.87
30_Y	34_G	0.547	0.87
466_G	469_I	0.546	0.87
51_E	61_F	0.545	0.87
42_V	50_V	0.544	0.86
37_A	41_T	0.544	0.86
225_S	228_N	0.544	0.86
133_L	168_G	0.543	0.86
540_S	543_G	0.541	0.86
191_V	196_Y	0.539	0.86
332_S	391_L	0.538	0.86
347_T	351_N	0.538	0.86
128_I	131_S	0.538	0.86
342_W	346_N	0.537	0.86
199_V	212_A	0.536	0.86
530_D	544_G	0.536	0.86
545_I	548_N	0.536	0.86
42_V	60_F	0.535	0.86
345_S	357_Q	0.535	0.86
91_Y	296_L	0.534	0.85
309_E	312_P	0.533	0.85
50_V	53_A	0.533	0.85
396_T	399_S	0.532	0.85
336_A	342_W	0.531	0.85
429_Q	433_S	0.531	0.85
297_S	525_H	0.531	0.85
199_V	204_Y	0.530	0.85
211_S	216_Y	0.530	0.85
53_A	61_F	0.529	0.85
66_L	70_G	0.529	0.85
91_Y	95_L	0.529	0.85
365_R	397_K	0.528	0.85
193_L	199_V	0.527	0.85
343_F	349_A	0.527	0.85
194_P	199_V	0.526	0.85
172_W	177_L	0.526	0.85
304_R	529_Y	0.526	0.85
486_E	489_R	0.526	0.85
206_P	211_S	0.526	0.85
23_F	27_A	0.525	0.84
248_T	457_A	0.525	0.84
336_A	397_K	0.525	0.84
407_Y	411_F	0.525	0.84
219_A	229_S	0.524	0.84
191_V	199_V	0.524	0.84
68_L	71_R	0.523	0.84
279_E	284_A	0.523	0.84
338_Q	398_G	0.523	0.84
220_R	229_S	0.523	0.84
164_V	175_I	0.522	0.84
45_G	51_E	0.519	0.84
221_V	228_N	0.519	0.84
275_K	447_S	0.517	0.84
391_L	532_I	0.517	0.84
283_A	496_M	0.517	0.84
44_K	51_E	0.517	0.84
109_T	114_L	0.517	0.84
472_R	476_H	0.515	0.83
336_A	343_F	0.514	0.83
53_A	62_L	0.514	0.83
16_L	23_F	0.513	0.83
92_M	99_I	0.513	0.83
446_S	449_I	0.512	0.83
526_V	530_D	0.512	0.83
163_V	171_V	0.512	0.83
47_S	65_L	0.510	0.83
494_V	531_T	0.510	0.83
168_G	175_I	0.510	0.83
19_Y	31_R	0.510	0.83
18_I	23_F	0.507	0.82
217_A	222_D	0.505	0.82
259_R	297_S	0.504	0.82
199_V	202_N	0.504	0.82
114_L	119_V	0.504	0.82
261_D	277_A	0.504	0.82
225_S	231_L	0.503	0.82
59_T	66_L	0.503	0.82
17_A	20_I	0.502	0.82
57_L	60_F	0.502	0.82
51_E	57_L	0.502	0.82
331_S	386_P	0.500	0.82
206_P	214_G	0.500	0.82
480_R	483_A	0.500	0.82

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4kavA	1	0.5719	100	0.547	Contact Map
2w5qA	1	0.5595	100	0.547	Contact Map
4uorA	3	0.556	100	0.549	Contact Map
2w8dA	1	0.5613	100	0.55	Contact Map
3lxqA	1	0.5613	100	0.552	Contact Map
4uopA	2	0.5666	100	0.553	Contact Map
4tn0A	1	0.5329	100	0.555	Contact Map
4upkA	3	0.5293	100	0.563	Contact Map
2vqrA	3	0.5293	100	0.564	Contact Map
4uphA	2	0.5275	100	0.564	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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