YHJK - ECOLI - GREMLIN Contacts

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YHJK - Protein YhjK

UniProt:	P37649	Sequences: MRVSRSLTIKQMAMVAAVVLVFVFIFCTVLLFHLVQQNRYNTATQLESIARSVREPLSSAILKGDIPEAEAILASIKPAGVVSRADVVLPNQFQALRKSFIPERPVPVMVTRLFELPVQISLGVYSLERPANPQPIAYLVLQADSFRMYKFVMSTLSTLVTIYLLLSLILTVAISWCINRLILHPLRNIARELNAIPAKELVGHQLALPRLHQDDEIGMLVRSYNLNQQLLQRHYEEQNENAMRFPVSDLPNKALLMEMLEQVVARKQTTALMIITCETLRDTAGVLKEAQREILLLTLVEKLKSVLSPRMILAQISGYDFAVIANGVQEPWHAITLGQQVLTIMSERLPIERIQLRPHCSIGVAMFYGDLTAEQLYSRAISAAFTARHKGKNQIQFFDPQQMEAAQKRLTEESDILNALENHQFAIWLQPQVEMTSGKLVSAEVLLRIQQPDGSWDLPDGLIDRIECCGLMVTVGHWVLEESCRLLAAWQERGIMLPLSVNLSALQLMHPNMVADMLELLTRYRIQPGTLILEVTESRRIDDPHAAVAILRPLRNAGVRVALDDFGMGYAGLRQLQHMKSLPIDVLKIDKMFVEGLPGDSSMIAAIIMLAQSLNLQMIAEGVETEAQRDWLAKAGVGIAQGFLFARPLPIEIFEESYLEEK	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG12256
Length:	662 (605)
Sequences:	5752 (4908)
Seq/√Len:	199.5

ECOLI - YHJK YLIE CSRD DOSP YEGE YFGF GMR YFEA YLAB YJCC RTN YCGG ADRB BLUF YAHA
BACSU - YKOW

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
443_A	654_F	5.650	1.00
646_A	649_L	4.903	1.00
591_K	595_E	4.800	1.00
481_E	523_R	4.672	1.00
476_G	507_Q	4.603	1.00
308_S	311_M	4.546	1.00
435_M	640_A	4.383	1.00
240_E	244_R	4.255	1.00
555_R	585_D	4.052	1.00
408_K	461_G	4.029	1.00
623_V	640_A	3.861	1.00
612_Q	638_G	3.475	1.00
518_L	557_A	3.261	1.00
434_E	437_S	3.256	1.00
256_L	322_A	3.250	1.00
626_E	630_D	3.158	1.00
426_A	450_Q	3.126	1.00
477_H	516_D	3.121	1.00
415_D	451_Q	3.114	1.00
429_L	486_L	3.114	1.00
372_T	375_Q	3.071	1.00
486_L	490_W	3.023	1.00
520_L	524_Y	2.995	1.00
482_E	485_R	2.903	1.00
427_I	478_W	2.809	1.00
503_L	513_M	2.787	1.00
273_M	362_I	2.760	1.00
451_Q	455_S	2.704	1.00
231_L	235_Y	2.643	1.00
631_W	635_A	2.632	1.00
466_I	475_V	2.616	1.00
488_A	492_E	2.555	1.00
486_L	651_I	2.533	1.00
532_I	586_V	2.505	1.00
447_L	479_V	2.267	1.00
433_V	645_F	2.266	1.00
425_F	447_L	2.256	1.00
428_W	650_P	2.252	1.00
551_L	561_V	2.248	1.00
451_Q	454_G	2.244	1.00
650_P	653_I	2.234	1.00
423_H	482_E	2.203	1.00
629_R	640_A	2.178	1.00
228_Q	232_Q	2.166	1.00
227_N	232_Q	2.153	1.00
259_M	312_I	2.135	1.00
562_A	586_V	2.129	1.00
424_Q	451_Q	2.126	1.00
273_M	338_G	2.116	1.00
255_L	259_M	2.115	1.00
484_C	520_L	2.097	1.00
338_G	364_V	2.095	1.00
490_W	651_I	2.086	1.00
629_R	645_F	2.082	1.00
452_P	455_S	2.066	1.00
481_E	524_Y	2.037	1.00
307_L	313_L	2.005	1.00
491_Q	527_Q	1.997	1.00
294_I	297_L	1.992	1.00
325_A	337_L	1.955	1.00
232_Q	235_Y	1.949	1.00
271_A	366_M	1.944	1.00
478_W	482_E	1.944	1.00
227_N	231_L	1.925	1.00
491_Q	530_T	1.914	1.00
432_Q	532_I	1.904	1.00
432_Q	586_V	1.899	1.00
260_L	373_A	1.896	1.00
617_Q	638_G	1.892	1.00
427_I	479_V	1.872	1.00
626_E	644_L	1.868	1.00
284_A	292_R	1.864	1.00
255_L	312_I	1.829	1.00
427_I	483_S	1.805	1.00
482_E	486_L	1.801	1.00
505_A	538_S	1.800	1.00
487_L	526_I	1.787	1.00
432_Q	639_I	1.786	1.00
275_I	360_C	1.780	1.00
334_A	338_G	1.779	1.00
560_R	585_D	1.762	1.00
215_D	218_G	1.757	1.00
625_T	628_Q	1.749	1.00
580_K	596_G	1.747	1.00
189_I	193_L	1.731	1.00
517_M	554_L	1.729	1.00
447_L	475_V	1.724	1.00
432_Q	442_S	1.718	1.00
298_T	301_E	1.711	1.00
213_Q	216_E	1.709	1.00
367_F	376_L	1.709	1.00
563_L	584_I	1.701	1.00
279_T	392_K	1.689	1.00
409_R	468_C	1.684	1.00
447_L	478_W	1.684	1.00
586_V	619_I	1.681	1.00
426_A	456_W	1.678	1.00
643_F	648_P	1.676	1.00
601_S	631_W	1.667	1.00
295_L	358_P	1.658	1.00
251_P	255_L	1.649	1.00
412_E	465_R	1.637	1.00
278_E	361_S	1.619	1.00
598_P	601_S	1.617	1.00
294_I	352_E	1.581	1.00
415_D	454_G	1.573	1.00
598_P	631_W	1.572	1.00
350_P	353_R	1.570	1.00
487_L	499_L	1.559	1.00
521_L	559_V	1.549	1.00
629_R	644_L	1.547	1.00
320_D	381_I	1.538	1.00
428_W	456_W	1.537	1.00
259_M	262_Q	1.522	1.00
608_I	635_A	1.511	1.00
424_Q	449_I	1.510	1.00
653_I	656_E	1.500	1.00
450_Q	456_W	1.497	1.00
370_D	397_F	1.492	1.00
284_A	318_G	1.486	1.00
591_K	622_G	1.481	1.00
605_A	613_S	1.479	1.00
513_M	517_M	1.477	1.00
185_P	189_I	1.474	1.00
620_A	632_L	1.471	1.00
387_A	396_Q	1.468	1.00
463_I	472_M	1.462	1.00
598_P	627_A	1.459	1.00
274_I	384_A	1.455	1.00
212_H	216_E	1.450	1.00
480_L	501_V	1.447	1.00
318_G	385_F	1.446	1.00
629_R	633_A	1.443	1.00
218_G	221_V	1.443	1.00
381_I	385_F	1.437	1.00
276_T	385_F	1.435	1.00
390_K	396_Q	1.432	1.00
303_L	313_L	1.422	1.00
427_I	447_L	1.418	1.00
501_V	531_L	1.418	1.00
418_N	424_Q	1.417	1.00
424_Q	452_P	1.401	1.00
418_N	422_N	1.398	1.00
289_E	381_I	1.396	1.00
518_L	553_P	1.395	1.00
189_I	192_E	1.384	1.00
620_A	637_V	1.373	1.00
460_D	591_K	1.372	1.00
210_R	221_V	1.371	1.00
229_Q	232_Q	1.370	1.00
235_Y	239_N	1.368	1.00
454_G	457_D	1.362	1.00
481_E	520_L	1.362	1.00
503_L	533_L	1.361	1.00
532_I	562_A	1.354	1.00
527_Q	530_T	1.353	1.00
281_R	385_F	1.351	1.00
276_T	388_R	1.350	1.00
289_E	385_F	1.348	1.00
500_S	532_I	1.342	1.00
256_L	324_I	1.342	1.00
521_L	528_P	1.340	1.00
584_I	616_L	1.339	1.00
490_W	655_E	1.332	1.00
432_Q	619_I	1.330	1.00
508_L	551_L	1.328	1.00
329_Q	333_H	1.323	1.00
294_I	298_T	1.321	1.00
238_Q	241_N	1.321	1.00
612_Q	618_M	1.309	1.00
193_L	196_I	1.297	1.00
240_E	249_D	1.297	1.00
273_M	323_V	1.295	1.00
271_A	334_A	1.291	1.00
299_L	345_M	1.288	1.00
587_L	611_A	1.279	1.00
277_C	360_C	1.276	1.00
597_L	631_W	1.273	1.00
221_V	225_N	1.261	1.00
322_A	377_Y	1.260	1.00
484_C	531_L	1.259	1.00
277_C	299_L	1.258	1.00
531_L	559_V	1.246	1.00
605_A	635_A	1.242	1.00
480_L	520_L	1.239	1.00
487_L	491_Q	1.239	1.00
608_I	637_V	1.226	1.00
212_H	221_V	1.225	1.00
269_T	369_G	1.224	1.00
230_L	233_R	1.219	1.00
416_I	419_A	1.219	1.00
217_I	221_V	1.219	1.00
255_L	258_E	1.218	1.00
342_L	362_I	1.213	1.00
284_A	293_E	1.212	1.00
434_E	439_K	1.212	1.00
516_D	520_L	1.204	1.00
359_H	393_N	1.203	1.00
302_K	349_L	1.199	1.00
480_L	533_L	1.197	1.00
335_I	339_Q	1.192	1.00
285_G	385_F	1.192	1.00
186_L	189_I	1.187	1.00
623_V	632_L	1.185	1.00
285_G	381_I	1.184	1.00
295_L	349_L	1.182	1.00
416_I	425_F	1.182	1.00
617_Q	639_I	1.179	1.00
498_P	560_R	1.176	1.00
258_E	312_I	1.173	1.00
466_I	472_M	1.170	1.00
429_L	445_V	1.166	1.00
231_L	234_H	1.165	1.00
214_D	218_G	1.162	1.00
480_L	517_M	1.159	1.00
216_E	221_V	1.153	1.00
216_E	225_N	1.149	1.00
215_D	221_V	1.146	1.00
308_S	337_L	1.144	1.00
311_M	340_Q	1.142	1.00
339_Q	343_T	1.138	1.00
605_A	609_M	1.137	1.00
630_D	633_A	1.132	1.00
282_D	413_E	1.130	1.00
640_A	645_F	1.129	1.00
485_R	524_Y	1.127	1.00
264_V	367_F	1.123	1.00
608_I	612_Q	1.120	1.00
245_F	315_Q	1.117	1.00
335_I	397_F	1.116	1.00
298_T	302_K	1.113	1.00
433_V	438_G	1.112	1.00
227_N	235_Y	1.112	1.00
89_L	93_F	1.110	1.00
488_A	491_Q	1.107	1.00
483_S	499_L	1.106	1.00
435_M	629_R	1.105	1.00
345_M	349_L	1.102	1.00
519_E	523_R	1.102	1.00
565_D	621_E	1.100	1.00
517_M	533_L	1.098	1.00
351_I	356_L	1.094	1.00
279_T	413_E	1.093	1.00
364_V	397_F	1.092	1.00
649_L	653_I	1.091	1.00
417_L	471_L	1.091	1.00
350_P	355_Q	1.089	1.00
426_A	650_P	1.088	1.00
216_E	220_L	1.083	1.00
258_E	262_Q	1.083	1.00
190_A	194_N	1.082	1.00
182_I	185_P	1.080	1.00
457_D	464_D	1.080	1.00
382_S	402_Q	1.079	1.00
386_T	389_H	1.079	1.00
445_V	499_L	1.077	1.00
298_T	349_L	1.077	1.00
498_P	532_I	1.074	1.00
274_I	322_A	1.074	1.00
276_T	319_Y	1.073	1.00
213_Q	218_G	1.072	1.00
493_R	655_E	1.068	1.00
290_A	374_E	1.068	1.00
317_S	385_F	1.067	1.00
451_Q	457_D	1.066	1.00
199_K	203_G	1.064	1.00
243_M	254_A	1.063	1.00
220_L	224_Y	1.063	1.00
432_Q	500_S	1.059	1.00
467_E	472_M	1.056	1.00
306_V	341_V	1.055	1.00
509_M	542_D	1.054	1.00
264_V	270_T	1.051	1.00
239_N	243_M	1.051	1.00
256_L	314_A	1.048	1.00
413_E	417_L	1.048	1.00
543_D	546_A	1.047	1.00
200_E	203_G	1.046	1.00
423_H	481_E	1.044	1.00
486_L	655_E	1.041	1.00
308_S	340_Q	1.041	1.00
521_L	526_I	1.039	1.00
237_E	241_N	1.037	1.00
598_P	628_Q	1.035	1.00
580_K	600_D	1.034	1.00
370_D	379_R	1.033	1.00
606_A	613_S	1.033	1.00
408_K	454_G	1.030	1.00
355_Q	418_N	1.029	1.00
484_C	524_Y	1.029	1.00
551_L	583_P	1.029	1.00
281_R	285_G	1.028	1.00
197_P	201_L	1.026	1.00
278_E	392_K	1.018	1.00
626_E	629_R	1.017	1.00
279_T	282_D	1.015	1.00
454_G	461_G	1.015	1.00
276_T	284_A	1.007	1.00
220_L	223_S	1.006	1.00
307_L	323_V	1.005	1.00
259_M	314_A	1.002	1.00
316_I	322_A	1.000	1.00
425_F	478_W	0.994	1.00
256_L	260_L	0.994	1.00
278_E	388_R	0.992	1.00
533_L	561_V	0.990	1.00
260_L	324_I	0.984	1.00
291_Q	356_L	0.980	1.00
185_P	218_G	0.979	1.00
441_V	639_I	0.977	1.00
179_N	183_L	0.974	0.99
35_V	39_R	0.974	0.99
594_V	604_I	0.971	0.99
263_V	270_T	0.970	0.99
233_R	237_E	0.970	0.99
608_I	638_G	0.965	0.99
632_L	637_V	0.965	0.99
611_A	618_M	0.964	0.99
342_L	395_I	0.963	0.99
496_M	530_T	0.962	0.99
365_A	379_R	0.962	0.99
586_V	617_Q	0.961	0.99
458_L	464_D	0.961	0.99
415_D	452_P	0.961	0.99
444_E	502_N	0.958	0.99
595_E	628_Q	0.956	0.99
415_D	453_D	0.954	0.99
345_M	360_C	0.952	0.99
630_D	634_K	0.951	0.99
291_Q	354_I	0.949	0.99
449_I	455_S	0.944	0.99
302_K	348_R	0.943	0.99
185_P	216_E	0.939	0.99
508_L	513_M	0.939	0.99
236_E	239_N	0.938	0.99
275_I	323_V	0.938	0.99
457_D	463_I	0.936	0.99
189_I	197_P	0.936	0.99
488_A	524_Y	0.934	0.99
375_Q	379_R	0.934	0.99
483_S	501_V	0.934	0.99
247_V	293_E	0.930	0.99
132_N	137_A	0.928	0.99
325_A	334_A	0.927	0.99
518_L	522_T	0.926	0.99
480_L	531_L	0.924	0.99
475_V	479_V	0.924	0.99
133_P	137_A	0.923	0.99
253_K	381_I	0.923	0.99
489_A	493_R	0.923	0.99
486_L	489_A	0.922	0.99
471_L	474_T	0.920	0.99
386_T	396_Q	0.919	0.99
280_L	296_L	0.918	0.99
515_A	553_P	0.917	0.99
363_G	380_A	0.916	0.99
246_P	249_D	0.914	0.99
335_I	395_I	0.913	0.99
134_Q	137_A	0.912	0.99
234_H	241_N	0.912	0.99
195_A	200_E	0.912	0.99
416_I	466_I	0.910	0.99
301_E	304_K	0.909	0.99
474_T	477_H	0.909	0.99
367_F	370_D	0.905	0.99
338_G	395_I	0.904	0.99
175_S	178_I	0.903	0.99
536_T	565_D	0.902	0.99
283_T	292_R	0.900	0.99
521_L	524_Y	0.897	0.99
228_Q	231_L	0.894	0.99
368_Y	376_L	0.892	0.99
488_A	525_R	0.888	0.99
320_D	385_F	0.887	0.99
213_Q	217_I	0.885	0.99
238_Q	243_M	0.884	0.99
477_H	481_E	0.881	0.99
463_I	466_I	0.879	0.99
247_V	284_A	0.879	0.99
485_R	489_A	0.879	0.99
251_P	312_I	0.875	0.99
598_P	625_T	0.874	0.99
361_S	391_G	0.871	0.99
292_R	318_G	0.870	0.99
473_V	510_H	0.870	0.99
442_S	498_P	0.868	0.99
548_V	583_P	0.868	0.99
463_I	536_T	0.867	0.99
427_I	445_V	0.864	0.99
319_Y	388_R	0.864	0.99
398_F	403_M	0.862	0.99
263_V	312_I	0.860	0.99
628_Q	644_L	0.859	0.99
491_Q	494_G	0.859	0.99
601_S	605_A	0.856	0.99
197_P	200_E	0.856	0.99
548_V	581_S	0.852	0.99
89_L	92_Q	0.851	0.99
544_P	582_L	0.850	0.99
379_R	403_M	0.850	0.99
514_V	518_L	0.850	0.99
469_C	473_V	0.849	0.99
603_M	610_L	0.845	0.99
244_R	255_L	0.845	0.99
300_V	313_L	0.845	0.99
221_V	224_Y	0.845	0.99
287_L	354_I	0.842	0.99
262_Q	326_N	0.840	0.98
568_M	592_M	0.837	0.98
210_R	214_D	0.836	0.98
274_I	380_A	0.836	0.98
210_R	216_E	0.835	0.98
517_M	559_V	0.834	0.98
283_T	295_L	0.833	0.98
281_R	289_E	0.832	0.98
399_D	402_Q	0.832	0.98
597_L	604_I	0.828	0.98
266_R	326_N	0.821	0.98
270_T	367_F	0.819	0.98
237_E	240_E	0.819	0.98
460_D	464_D	0.817	0.98
193_L	197_P	0.815	0.98
473_V	476_G	0.814	0.98
426_A	652_E	0.813	0.98
293_E	318_G	0.811	0.98
250_L	300_V	0.811	0.98
387_A	394_Q	0.807	0.98
317_S	381_I	0.806	0.98
323_V	341_V	0.806	0.98
281_R	284_A	0.805	0.98
503_L	507_Q	0.805	0.98
280_L	388_R	0.802	0.98
443_A	499_L	0.802	0.98
602_S	613_S	0.800	0.98
270_T	324_I	0.800	0.98
597_L	601_S	0.799	0.98
552_R	556_N	0.799	0.98
526_I	531_L	0.796	0.98
610_L	614_L	0.795	0.98
338_G	362_I	0.795	0.98
651_I	655_E	0.794	0.98
533_L	559_V	0.793	0.98
263_V	266_R	0.793	0.98
283_T	356_L	0.793	0.98
175_S	179_N	0.790	0.98
385_F	388_R	0.788	0.98
481_E	485_R	0.786	0.98
428_W	450_Q	0.785	0.98
165_L	175_S	0.784	0.98
210_R	213_Q	0.784	0.98
596_G	600_D	0.784	0.98
261_E	373_A	0.783	0.98
618_M	638_G	0.783	0.98
532_I	560_R	0.781	0.98
436_T	633_A	0.780	0.98
307_L	311_M	0.779	0.98
349_L	358_P	0.779	0.98
217_I	220_L	0.778	0.98
278_E	391_G	0.776	0.97
192_E	200_E	0.775	0.97
268_Q	327_G	0.773	0.97
418_N	421_E	0.772	0.97
272_L	376_L	0.770	0.97
416_I	420_L	0.769	0.97
291_Q	351_I	0.767	0.97
508_L	539_R	0.767	0.97
364_V	395_I	0.766	0.97
46_L	50_A	0.765	0.97
164_L	175_S	0.764	0.97
228_Q	235_Y	0.764	0.97
368_Y	379_R	0.764	0.97
313_L	323_V	0.762	0.97
289_E	320_D	0.762	0.97
363_G	383_A	0.761	0.97
361_S	388_R	0.758	0.97
419_A	425_F	0.756	0.97
467_E	504_S	0.756	0.97
359_H	391_G	0.756	0.97
193_L	201_L	0.756	0.97
433_V	440_L	0.755	0.97
484_C	526_I	0.755	0.97
92_Q	98_K	0.753	0.97
550_I	553_P	0.752	0.97
544_P	547_A	0.751	0.97
317_S	320_D	0.751	0.97
293_E	315_Q	0.750	0.97
552_R	583_P	0.749	0.97
337_L	340_Q	0.749	0.97
500_S	586_V	0.749	0.97
297_L	301_E	0.748	0.97
328_V	334_A	0.748	0.97
429_L	483_S	0.746	0.97
175_S	183_L	0.745	0.97
338_G	342_L	0.745	0.97
526_I	530_T	0.745	0.97
285_G	289_E	0.745	0.97
196_I	201_L	0.744	0.97
227_N	230_L	0.743	0.97
137_A	141_L	0.742	0.97
649_L	654_F	0.741	0.97
89_L	94_Q	0.740	0.97
199_K	202_V	0.740	0.97
263_V	326_N	0.739	0.97
50_A	54_R	0.738	0.97
253_K	293_E	0.737	0.97
276_T	292_R	0.736	0.97
434_E	638_G	0.735	0.97
622_G	628_Q	0.734	0.96
328_V	333_H	0.734	0.96
537_E	567_G	0.733	0.96
299_L	349_L	0.732	0.96
463_I	467_E	0.732	0.96
417_L	474_T	0.731	0.96
234_H	237_E	0.731	0.96
243_M	258_E	0.731	0.96
86_D	89_L	0.731	0.96
212_H	218_G	0.730	0.96
86_D	92_Q	0.729	0.96
520_L	523_R	0.729	0.96
65_D	68_E	0.727	0.96
434_E	441_V	0.724	0.96
440_L	646_A	0.723	0.96
594_V	620_A	0.722	0.96
243_M	251_P	0.722	0.96
386_T	390_K	0.721	0.96
534_E	588_K	0.721	0.96
619_I	639_I	0.720	0.96
346_S	393_N	0.720	0.96
366_M	397_F	0.720	0.96
549_A	552_R	0.720	0.96
210_R	225_N	0.719	0.96
357_R	417_L	0.719	0.96
211_L	215_D	0.718	0.96
498_P	530_T	0.718	0.96
443_A	497_L	0.717	0.96
536_T	621_E	0.715	0.96
643_F	647_R	0.714	0.96
185_P	193_L	0.713	0.96
276_T	320_D	0.713	0.96
490_W	654_F	0.713	0.96
279_T	468_C	0.710	0.96
192_E	197_P	0.710	0.96
276_T	285_G	0.709	0.96
586_V	639_I	0.709	0.96
472_M	536_T	0.709	0.96
473_V	507_Q	0.708	0.96
240_E	243_M	0.708	0.96
284_A	319_Y	0.708	0.96
514_V	557_A	0.708	0.96
276_T	281_R	0.708	0.96
624_E	643_F	0.707	0.96
535_V	551_L	0.707	0.96
573_L	593_F	0.706	0.96
280_L	292_R	0.705	0.96
446_L	536_T	0.705	0.96
278_E	359_H	0.705	0.96
197_P	202_V	0.703	0.96
487_L	524_Y	0.701	0.95
311_M	337_L	0.701	0.95
508_L	550_I	0.701	0.95
292_R	381_I	0.700	0.95
512_N	516_D	0.700	0.95
603_M	607_I	0.699	0.95
442_S	532_I	0.698	0.95
212_H	215_D	0.698	0.95
450_Q	455_S	0.698	0.95
280_L	284_A	0.696	0.95
28_T	32_F	0.696	0.95
514_V	550_I	0.695	0.95
391_G	394_Q	0.695	0.95
423_H	478_W	0.692	0.95
261_E	265_A	0.691	0.95
445_V	483_S	0.691	0.95
548_V	552_R	0.691	0.95
281_R	292_R	0.689	0.95
209_P	224_Y	0.689	0.95
274_I	381_I	0.689	0.95
416_I	471_L	0.687	0.95
466_I	470_G	0.687	0.95
196_I	199_K	0.685	0.95
211_L	224_Y	0.684	0.95
285_G	292_R	0.683	0.95
276_T	289_E	0.682	0.95
70_E	74_A	0.682	0.95
274_I	281_R	0.681	0.95
609_M	613_S	0.679	0.95
334_A	366_M	0.677	0.95
275_I	362_I	0.676	0.94
289_E	318_G	0.676	0.94
541_I	578_H	0.676	0.94
133_P	136_I	0.674	0.94
185_P	190_A	0.673	0.94
390_K	394_Q	0.672	0.94
412_E	415_D	0.672	0.94
411_T	453_D	0.671	0.94
293_E	381_I	0.670	0.94
163_Y	175_S	0.670	0.94
344_I	347_E	0.670	0.94
420_L	475_V	0.670	0.94
197_P	203_G	0.669	0.94
209_P	218_G	0.666	0.94
435_M	623_V	0.665	0.94
477_H	519_E	0.661	0.94
89_L	95_A	0.660	0.94
336_T	340_Q	0.660	0.94
212_H	224_Y	0.658	0.94
463_I	504_S	0.656	0.94
38_N	42_T	0.656	0.94
280_L	319_Y	0.654	0.93
540_R	563_L	0.653	0.93
276_T	381_I	0.652	0.93
502_N	534_E	0.651	0.93
419_A	424_Q	0.650	0.93
546_A	550_I	0.650	0.93
209_P	213_Q	0.648	0.93
491_Q	496_M	0.646	0.93
209_P	212_H	0.645	0.93
196_I	200_E	0.645	0.93
430_Q	624_E	0.644	0.93
281_R	320_D	0.643	0.93
365_A	376_L	0.641	0.93
594_V	637_V	0.641	0.93
242_A	252_N	0.640	0.93
88_V	94_Q	0.640	0.93
284_A	296_L	0.638	0.93
289_E	292_R	0.638	0.93
506_L	539_R	0.637	0.93
608_I	618_M	0.637	0.93
224_Y	227_N	0.636	0.92
312_I	324_I	0.636	0.92
192_E	199_K	0.636	0.92
214_D	221_V	0.636	0.92
318_G	381_I	0.635	0.92
631_W	634_K	0.634	0.92
432_Q	498_P	0.633	0.92
243_M	255_L	0.632	0.92
469_C	474_T	0.632	0.92
284_A	388_R	0.632	0.92
469_C	472_M	0.631	0.92
537_E	590_D	0.631	0.92
339_Q	342_L	0.630	0.92
241_N	432_Q	0.630	0.92
450_Q	454_G	0.630	0.92
415_D	449_I	0.628	0.92
259_M	263_V	0.628	0.92
452_P	456_W	0.628	0.92
69_A	72_I	0.628	0.92
209_P	215_D	0.627	0.92
425_F	466_I	0.626	0.92
178_I	185_P	0.625	0.92
216_E	223_S	0.624	0.92
331_P	335_I	0.624	0.92
192_E	196_I	0.622	0.92
361_S	392_K	0.622	0.92
502_N	564_D	0.622	0.92
289_E	388_R	0.622	0.92
627_A	630_D	0.621	0.92
276_T	280_L	0.621	0.92
281_R	381_I	0.621	0.92
94_Q	97_R	0.620	0.92
303_L	307_L	0.620	0.92
253_K	320_D	0.619	0.91
167_S	171_T	0.618	0.91
260_L	272_L	0.617	0.91
342_L	393_N	0.616	0.91
183_L	187_R	0.614	0.91
86_D	95_A	0.614	0.91
213_Q	221_V	0.614	0.91
420_L	478_W	0.613	0.91
407_Q	411_T	0.613	0.91
569_G	621_E	0.613	0.91
272_L	324_I	0.612	0.91
517_M	520_L	0.612	0.91
331_P	369_G	0.612	0.91
459_P	464_D	0.612	0.91
128_E	132_N	0.611	0.91
220_L	225_N	0.610	0.91
406_A	410_L	0.608	0.91
137_A	144_D	0.608	0.91
168_L	175_S	0.608	0.91
448_R	502_N	0.607	0.91
477_H	510_H	0.607	0.91
212_H	217_I	0.607	0.91
31_L	35_V	0.606	0.91
235_Y	238_Q	0.605	0.91
287_L	356_L	0.605	0.91
359_H	392_K	0.604	0.90
128_E	137_A	0.603	0.90
211_L	218_G	0.603	0.90
273_M	325_A	0.601	0.90
337_L	341_V	0.601	0.90
187_R	190_A	0.601	0.90
168_L	171_T	0.601	0.90
211_L	221_V	0.600	0.90
342_L	360_C	0.597	0.90
408_K	412_E	0.597	0.90
234_H	238_Q	0.596	0.90
421_E	474_T	0.596	0.90
190_A	197_P	0.596	0.90
480_L	484_C	0.596	0.90
289_E	293_E	0.595	0.90
602_S	606_A	0.595	0.90
517_M	531_L	0.595	0.90
247_V	297_L	0.593	0.90
375_Q	378_S	0.593	0.90
257_M	261_E	0.592	0.90
132_N	136_I	0.592	0.90
487_L	531_L	0.590	0.89
141_L	144_D	0.590	0.89
401_Q	404_E	0.589	0.89
292_R	319_Y	0.589	0.89
587_L	616_L	0.588	0.89
411_T	415_D	0.587	0.89
611_A	615_N	0.587	0.89
196_I	202_V	0.586	0.89
499_L	526_I	0.586	0.89
278_E	393_N	0.586	0.89
514_V	554_L	0.585	0.89
290_A	378_S	0.585	0.89
381_I	384_A	0.584	0.89
285_G	320_D	0.584	0.89
186_L	216_E	0.584	0.89
43_A	47_E	0.582	0.89
281_R	384_A	0.582	0.89
580_K	603_M	0.581	0.89
568_M	621_E	0.581	0.89
281_R	319_Y	0.580	0.89
244_R	251_P	0.578	0.88
604_I	620_A	0.578	0.88
193_L	200_E	0.577	0.88
54_R	58_S	0.577	0.88
480_L	559_V	0.576	0.88
652_E	655_E	0.576	0.88
459_P	462_L	0.576	0.88
618_M	622_G	0.574	0.88
339_Q	395_I	0.574	0.88
505_A	508_L	0.573	0.88
271_A	364_V	0.573	0.88
449_I	637_V	0.572	0.88
510_H	516_D	0.572	0.88
291_Q	294_I	0.571	0.88
536_T	593_F	0.571	0.88
247_V	315_Q	0.570	0.88
459_P	565_D	0.570	0.88
192_E	202_V	0.570	0.88
398_F	402_Q	0.570	0.88
82_V	85_A	0.569	0.88
400_P	404_E	0.569	0.88
284_A	381_I	0.569	0.88
565_D	571_A	0.568	0.88
387_A	391_G	0.567	0.87
572_G	593_F	0.567	0.87
446_L	621_E	0.567	0.87
447_L	462_L	0.567	0.87
217_I	224_Y	0.567	0.87
515_A	518_L	0.565	0.87
589_I	607_I	0.564	0.87
218_G	224_Y	0.564	0.87
185_P	221_V	0.562	0.87
217_I	223_S	0.562	0.87
428_W	448_R	0.562	0.87
489_A	492_E	0.561	0.87
446_L	565_D	0.561	0.87
472_M	506_L	0.561	0.87
164_L	168_L	0.561	0.87
565_D	569_G	0.561	0.87
590_D	621_E	0.561	0.87
361_S	385_F	0.559	0.87
590_D	593_F	0.558	0.87
193_L	203_G	0.558	0.87
246_P	254_A	0.556	0.86
210_R	217_I	0.556	0.86
514_V	553_P	0.555	0.86
257_M	374_E	0.554	0.86
403_M	407_Q	0.554	0.86
444_E	564_D	0.553	0.86
474_T	507_Q	0.552	0.86
438_G	633_A	0.552	0.86
180_R	183_L	0.551	0.86
308_S	328_V	0.551	0.86
304_K	313_L	0.549	0.86
306_V	344_I	0.549	0.86
192_E	203_G	0.549	0.86
505_A	578_H	0.548	0.86
189_I	201_L	0.547	0.86
193_L	199_K	0.547	0.86
505_A	535_V	0.545	0.85
39_R	43_A	0.545	0.85
317_S	361_S	0.544	0.85
196_I	203_G	0.544	0.85
430_Q	641_Q	0.544	0.85
281_R	388_R	0.544	0.85
296_L	318_G	0.543	0.85
65_D	73_L	0.543	0.85
577_Q	592_M	0.542	0.85
230_L	235_Y	0.541	0.85
66_I	70_E	0.540	0.85
263_V	324_I	0.539	0.85
34_L	38_N	0.539	0.85
553_P	556_N	0.538	0.85
57_L	60_A	0.538	0.85
510_H	513_M	0.538	0.85
429_L	443_A	0.537	0.85
508_L	538_S	0.537	0.85
258_E	261_E	0.537	0.85
299_L	303_L	0.537	0.85
477_H	507_Q	0.536	0.84
536_T	571_A	0.536	0.84
472_M	507_Q	0.535	0.84
175_S	193_L	0.535	0.84
175_S	180_R	0.535	0.84
274_I	316_I	0.534	0.84
342_L	359_H	0.534	0.84
174_I	177_C	0.534	0.84
479_V	483_S	0.534	0.84
512_N	515_A	0.534	0.84
281_R	293_E	0.534	0.84
255_L	263_V	0.534	0.84
594_V	597_L	0.533	0.84
210_R	224_Y	0.532	0.84
248_S	296_L	0.532	0.84
48_S	51_R	0.532	0.84
285_G	318_G	0.532	0.84
508_L	582_L	0.532	0.84
210_R	220_L	0.532	0.84
332_W	335_I	0.531	0.84
334_A	364_V	0.531	0.84
333_H	336_T	0.530	0.84
501_V	533_L	0.530	0.84
127_L	137_A	0.530	0.84
444_E	641_Q	0.529	0.84
128_E	136_I	0.529	0.84
334_A	397_F	0.529	0.84
42_T	46_L	0.527	0.83
276_T	317_S	0.527	0.83
281_R	317_S	0.527	0.83
286_V	410_L	0.527	0.83
413_E	465_R	0.527	0.83
193_L	224_Y	0.526	0.83
188_N	192_E	0.526	0.83
292_R	388_R	0.525	0.83
315_Q	318_G	0.524	0.83
555_R	561_V	0.524	0.83
433_V	646_A	0.523	0.83
303_L	341_V	0.522	0.83
534_E	564_D	0.522	0.83
343_T	346_S	0.522	0.83
419_A	462_L	0.521	0.83
209_P	221_V	0.521	0.83
476_G	479_V	0.520	0.83
365_A	380_A	0.520	0.83
278_E	320_D	0.520	0.83
502_N	641_Q	0.519	0.82
601_S	635_A	0.518	0.82
561_V	585_D	0.518	0.82
189_I	203_G	0.518	0.82
241_N	246_P	0.518	0.82
544_P	548_V	0.518	0.82
384_A	392_K	0.517	0.82
289_E	317_S	0.517	0.82
214_D	224_Y	0.517	0.82
24_F	28_T	0.517	0.82
56_P	60_A	0.517	0.82
53_V	57_L	0.516	0.82
39_R	42_T	0.516	0.82
190_A	193_L	0.516	0.82
281_R	361_S	0.516	0.82
211_L	220_L	0.516	0.82
476_G	503_L	0.515	0.82
516_D	519_E	0.515	0.82
442_S	639_I	0.515	0.82
284_A	289_E	0.515	0.82
195_A	202_V	0.514	0.82
343_T	347_E	0.514	0.82
446_L	502_N	0.514	0.82
87_V	92_Q	0.513	0.82
430_Q	564_D	0.513	0.82
280_L	361_S	0.512	0.82
45_Q	48_S	0.511	0.82
431_P	440_L	0.511	0.82
262_Q	312_I	0.511	0.82
177_C	183_L	0.511	0.82
273_M	364_V	0.511	0.82
318_G	384_A	0.511	0.82
605_A	631_W	0.510	0.81
480_L	503_L	0.510	0.81
476_G	538_S	0.510	0.81
214_D	220_L	0.509	0.81
23_V	26_F	0.508	0.81
477_H	520_L	0.508	0.81
591_K	628_Q	0.508	0.81
541_I	544_P	0.507	0.81
47_E	51_R	0.507	0.81
285_G	388_R	0.507	0.81
331_P	397_F	0.507	0.81
588_K	641_Q	0.507	0.81
92_Q	95_A	0.507	0.81
41_N	45_Q	0.507	0.81
467_E	593_F	0.506	0.81
92_Q	96_L	0.506	0.81
429_L	482_E	0.504	0.81
137_A	143_A	0.503	0.81
541_I	547_A	0.503	0.81
589_I	637_V	0.503	0.81
502_N	621_E	0.503	0.81
446_L	459_P	0.502	0.80
19_V	22_F	0.502	0.80
564_D	641_Q	0.500	0.80

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4rnhA	2	0.6193	100	0.318	Contact Map
4j40A	2	0.3761	100	0.322	Contact Map
3pjxA	1	0.6224	100	0.333	Contact Map
3gfzA	2	0.5619	100	0.44	Contact Map
4hjfA	1	0.3837	100	0.476	Contact Map
4hu4A	1	0.3625	100	0.543	Contact Map
2r6oA	2	0.3792	100	0.544	Contact Map
4kieA	1	0.3882	100	0.546	Contact Map
4rniA	2	0.3776	100	0.55	Contact Map
3sy8A	6	0.5876	100	0.558	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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