YHHS - ECOLI - GREMLIN Contacts

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YHHS - UPF0226 protein YhhS

UniProt:	P37621	Sequences: MPEPVAEPALNGLRLNLRIVSIVMFNFASYLTIGLPLAVLPGYVHDVMGFSAFWAGLVISLQYFATLLSRPHAGRYADSLGPKKIVVFGLCGCFLSGLGYLTAGLTASLPVISLLLLCLGRVILGIGQSFAGTGSTLWGVGVVGSLHIGRVISWNGIVTYGAMAMGAPLGVVFYHWGGLQALALIIMGVALVAILLAIPRPTVKASKGKPLPFRAVLGRVWLYGMALALASAGFGVIATFITLFYDAKGWDGAAFALTLFSCAFVGTRLLFPNGINRIGGLNVAMICFSVEIIGLLLVGVATMPWMAKIGVLLAGAGFSLVFPALGVVAVKAVPQQNQGAALATYTVFMDLSLGVTGPLAGLVMSWAGVPVIYLAAAGLVAIALLLTWRLKKRPPEHVPEAASSS	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG12219
Length:	405 (363)
Sequences:	169827 (121598)
Seq/√Len:	6382.2

ECOLI - YHHS YGCS GALP ENTS YAAU YFCJ ARAE MDFA NANT YDJE RHMT YJHB KGTP HSRA MDTM YDJK MDTH PROP GLPT XYLE YJJL UHPT YEBQ UHPC NEPI SOTB MDTG GUDP MHPT YHJE EXUT YDIN YIHP SHIA GARP YAJR TSGA DGOT YQCE YBJJ NARK MDTL MDTD YDHC LACY NARU YDIM YIHN ARAJ YEGT YDHP AMPG SETB YDEE BCR YNFM YHJX YIHO UIDB SETC YJIJ YDFJ NUPG FUCP XAPB CYNX SETA YGAY FSR YEAN EMRD YCAD YICJ EMRY LPLT YAGG MELB EMRB HCAT DTPA DTPB
BACSU - YFIG MMR ARAE YWOG YCXA YCNB YNCC YVMA YYCB IOLT YWTG YWFA YFMO NAIP CSBC YFHI YYBO YYAJ GLPT GUDP YHJO YBFB YFKF YJBB YFNC EXUT YTBD IOLF YFIS YYBF TCRB NASA CSBX YKUC YUBD YVQJ YFKL YBCL YQJV YXLH GUTA YXAM YITG YOAB YQGE YVKA YDDS YWBF YJMB YWOD LMRB PBUE YCEJ NARK YTTB YDEG YHCA GLCP YDGK YFMI YUXJ YNAJ BMR1 BMR3 BBEX BMR2 YDER YUSP YXIO YFIU YCLF
HALSA - O54630 Q9HS33 Q9HRX5 Q9HSM8 Q9HSK3 Q9HPD6 Q9HN67 Q9HMR5 Q9HMQ8 Q9HSE5
SULSO - Q97U43 Q97YL8 Q97U80 Q97WR1 Q7LX65 Q97U99 Q97UY7 Q7LX71 Q97VV2 Q97VU3 Q97WT1 Q97U98 Q97X63 Q97WS7 Q97UD8 Q97Y11 Q97VT2 Q97UR4 Q97YY8 Q97Y43 Q97U76 Q97X92 Q980K3 Q97VB7 Q97X47 Q97YH0 Q97V89 Q97XW7 Q97VQ5 Q97Z36 Q97ZC9 Q97VB9 Q97U91 Q97WR9 Q97VC8 Q97VD1 Q97YG2 Q97UJ4 Q97Z05 Q97X02 Q97Y15 Q97Z07 Q97WP8 Q97UK1 Q97U71 Q97YI4 Q97WJ7 Q97YW8 Q97UY6 Q97XG8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
104_G	116_L	3.918	1.00
82_P	141_G	3.895	1.00
99_G	120_G	3.808	1.00
92_G	127_G	3.608	1.00
101_L	184_L	3.209	1.00
65_A	122_V	3.159	1.00
96_S	120_G	2.939	1.00
73_A	130_F	2.917	1.00
143_V	151_V	2.842	1.00
89_G	130_F	2.813	1.00
78_D	339_G	2.755	1.00
114_L	118_C	2.733	1.00
113_S	116_L	2.733	1.00
115_L	119_L	2.708	1.00
333_V	341_A	2.649	1.00
94_F	190_A	2.645	1.00
96_S	127_G	2.579	1.00
214_R	218_G	2.483	1.00
149_G	276_N	2.440	1.00
147_H	150_R	2.395	1.00
51_S	54_W	2.390	1.00
83_K	87_V	2.327	1.00
232_A	356_T	2.326	1.00
263_A	312_L	2.302	1.00
290_V	317_G	2.262	1.00
297_L	310_G	2.247	1.00
280_G	331_K	2.225	1.00
69_S	126_I	2.214	1.00
144_G	147_H	2.209	1.00
96_S	123_I	2.206	1.00
228_A	352_S	2.190	1.00
54_W	114_L	2.184	1.00
77_A	134_G	2.095	1.00
374_L	378_G	2.058	1.00
23_V	158_V	2.038	1.00
334_P	337_N	2.036	1.00
305_W	309_I	2.002	1.00
103_A	116_L	1.994	1.00
177_G	181_A	1.964	1.00
267_T	316_A	1.908	1.00
103_A	120_G	1.881	1.00
81_G	84_K	1.864	1.00
98_L	187_M	1.851	1.00
273_N	277_R	1.834	1.00
299_G	374_L	1.793	1.00
94_F	194_I	1.750	1.00
279_G	282_N	1.732	1.00
96_S	124_L	1.729	1.00
212_P	215_A	1.699	1.00
101_L	187_M	1.695	1.00
58_V	117_L	1.690	1.00
65_A	69_S	1.689	1.00
75_R	79_S	1.682	1.00
61_L	118_C	1.675	1.00
303_M	306_M	1.660	1.00
100_Y	120_G	1.648	1.00
69_S	72_H	1.648	1.00
61_L	122_V	1.630	1.00
74_G	78_D	1.625	1.00
69_S	129_S	1.616	1.00
294_G	317_G	1.616	1.00
104_G	113_S	1.610	1.00
299_G	377_A	1.607	1.00
184_L	188_G	1.598	1.00
287_C	320_L	1.592	1.00
236_V	360_A	1.591	1.00
224_G	348_F	1.584	1.00
294_G	310_G	1.579	1.00
50_F	54_W	1.577	1.00
50_F	114_L	1.573	1.00
371_V	374_L	1.546	1.00
292_I	384_L	1.537	1.00
172_V	176_W	1.537	1.00
211_L	214_R	1.520	1.00
87_V	194_I	1.511	1.00
385_L	389_R	1.511	1.00
271_F	320_L	1.510	1.00
292_I	381_A	1.493	1.00
362_L	366_W	1.491	1.00
115_L	118_C	1.458	1.00
260_F	315_G	1.458	1.00
72_H	75_R	1.440	1.00
181_A	184_L	1.438	1.00
116_L	120_G	1.412	1.00
150_R	276_N	1.405	1.00
84_K	88_F	1.402	1.00
305_W	308_K	1.399	1.00
84_K	87_V	1.392	1.00
278_I	281_L	1.382	1.00
272_P	276_N	1.371	1.00
285_M	384_L	1.369	1.00
91_C	194_I	1.366	1.00
94_F	187_M	1.357	1.00
214_R	217_L	1.353	1.00
77_A	82_P	1.351	1.00
89_G	127_G	1.348	1.00
76_Y	85_I	1.346	1.00
263_A	267_T	1.338	1.00
80_L	85_I	1.326	1.00
367_A	371_V	1.325	1.00
371_V	375_A	1.324	1.00
140_V	148_I	1.319	1.00
178_G	181_A	1.319	1.00
168_P	258_T	1.315	1.00
195_L	199_P	1.312	1.00
141_G	338_Q	1.308	1.00
30_Y	159_T	1.303	1.00
76_Y	80_L	1.301	1.00
270_L	273_N	1.301	1.00
296_L	300_V	1.300	1.00
78_D	340_A	1.290	1.00
233_G	380_V	1.283	1.00
145_S	148_I	1.276	1.00
52_A	365_S	1.259	1.00
215_A	218_G	1.249	1.00
64_F	354_G	1.246	1.00
235_G	353_L	1.241	1.00
94_F	191_L	1.236	1.00
88_F	92_G	1.233	1.00
289_S	384_L	1.233	1.00
100_Y	117_L	1.225	1.00
92_G	96_S	1.222	1.00
274_G	278_I	1.217	1.00
267_T	270_L	1.215	1.00
244_F	248_K	1.201	1.00
285_M	388_W	1.199	1.00
282_N	285_M	1.193	1.00
278_I	282_N	1.191	1.00
255_F	259_L	1.183	1.00
281_L	285_M	1.183	1.00
286_I	290_V	1.177	1.00
370_P	374_L	1.176	1.00
98_L	102_T	1.167	1.00
273_N	276_N	1.165	1.00
60_S	358_P	1.155	1.00
352_S	356_T	1.152	1.00
378_G	382_I	1.151	1.00
304_P	308_K	1.142	1.00
195_L	198_I	1.138	1.00
337_N	340_A	1.136	1.00
90_L	194_I	1.135	1.00
80_L	84_K	1.130	1.00
148_I	331_K	1.120	1.00
139_G	155_N	1.119	1.00
294_G	313_L	1.118	1.00
363_V	367_A	1.115	1.00
32_T	35_L	1.111	1.00
83_K	202_T	1.110	1.00
215_A	337_N	1.110	1.00
220_V	224_G	1.107	1.00
168_P	172_V	1.104	1.00
296_L	377_A	1.104	1.00
201_P	204_K	1.101	1.00
374_L	377_A	1.100	1.00
54_W	118_C	1.099	1.00
269_L	273_N	1.099	1.00
53_F	57_L	1.093	1.00
294_G	314_A	1.089	1.00
309_I	312_L	1.086	1.00
25_F	131_A	1.081	1.00
173_F	181_A	1.073	1.00
99_G	102_T	1.070	1.00
67_L	354_G	1.064	1.00
81_G	85_I	1.064	1.00
93_C	127_G	1.063	1.00
87_V	197_A	1.061	1.00
279_G	283_V	1.058	1.00
291_E	380_V	1.052	1.00
361_G	365_S	1.047	1.00
205_A	210_P	1.042	1.00
292_I	296_L	1.038	1.00
196_L	199_P	1.038	1.00
289_S	293_I	1.035	1.00
264_F	319_S	1.034	1.00
57_L	358_P	1.032	1.00
288_F	383_A	1.031	1.00
60_S	354_G	1.030	1.00
329_A	345_Y	1.027	1.00
150_R	154_W	1.027	1.00
40_L	55_A	1.026	1.00
266_G	269_L	1.024	1.00
287_C	321_V	1.023	1.00
245_Y	250_W	1.021	1.00
381_A	385_L	1.019	1.00
18_R	142_V	1.016	1.00
246_D	253_A	1.016	1.00
65_A	125_G	1.014	1.00
221_W	225_M	1.009	1.00
87_V	198_I	1.004	1.00
119_L	123_I	0.999	1.00
71_P	75_R	0.996	1.00
31_L	166_G	0.996	1.00
84_K	202_T	0.993	1.00
62_Q	125_G	0.992	1.00
335_Q	338_Q	0.990	1.00
188_G	192_V	0.988	1.00
95_L	99_G	0.980	1.00
375_A	379_L	0.978	1.00
82_P	137_L	0.975	1.00
99_G	116_L	0.973	1.00
53_F	365_S	0.963	1.00
67_L	347_V	0.958	1.00
287_C	317_G	0.958	1.00
121_R	125_G	0.956	1.00
62_Q	128_Q	0.956	1.00
57_L	61_L	0.950	1.00
278_I	283_V	0.945	1.00
78_D	82_P	0.944	1.00
47_V	180_Q	0.944	1.00
226_A	387_T	0.933	1.00
21_S	196_L	0.932	1.00
81_G	202_T	0.927	1.00
285_M	289_S	0.924	1.00
85_I	88_F	0.923	1.00
191_L	195_L	0.922	1.00
297_L	300_V	0.916	1.00
309_I	313_L	0.911	1.00
290_V	294_G	0.907	1.00
243_L	247_A	0.904	1.00
375_A	378_G	0.903	1.00
56_G	240_F	0.902	1.00
116_L	119_L	0.901	1.00
140_V	338_Q	0.898	1.00
292_I	380_V	0.897	1.00
56_G	60_S	0.896	1.00
45_H	52_A	0.895	1.00
292_I	377_A	0.895	1.00
102_T	184_L	0.893	1.00
42_G	47_V	0.891	1.00
301_A	310_G	0.890	1.00
377_A	381_A	0.888	1.00
27_F	162_A	0.883	1.00
266_G	270_L	0.883	1.00
61_L	65_A	0.882	1.00
101_L	180_Q	0.882	1.00
54_W	57_L	0.882	1.00
217_L	221_W	0.880	1.00
82_P	202_T	0.878	1.00
74_G	339_G	0.876	1.00
231_S	349_M	0.876	1.00
262_C	266_G	0.876	1.00
306_M	309_I	0.872	1.00
295_L	299_G	0.869	1.00
173_F	177_G	0.863	1.00
211_L	215_A	0.863	1.00
143_V	147_H	0.863	1.00
263_A	266_G	0.861	1.00
288_F	384_L	0.860	1.00
245_Y	248_K	0.858	1.00
138_W	200_R	0.857	1.00
285_M	288_F	0.856	1.00
88_F	91_C	0.855	1.00
227_L	345_Y	0.853	1.00
87_V	91_C	0.850	1.00
160_Y	264_F	0.850	1.00
197_A	200_R	0.848	1.00
19_I	143_V	0.846	1.00
286_I	289_S	0.842	1.00
282_N	286_I	0.840	1.00
104_G	180_Q	0.840	1.00
184_L	187_M	0.830	1.00
294_G	297_L	0.828	1.00
39_V	174_Y	0.827	1.00
58_V	118_C	0.823	1.00
70_R	346_T	0.819	1.00
330_V	342_L	0.819	1.00
181_A	185_I	0.815	1.00
258_T	262_C	0.815	1.00
93_C	190_A	0.815	1.00
275_I	324_A	0.811	1.00
150_R	273_N	0.805	1.00
301_A	306_M	0.803	1.00
97_G	186_I	0.803	1.00
320_L	324_A	0.803	1.00
152_I	327_V	0.802	1.00
323_P	327_V	0.801	1.00
386_L	390_L	0.798	1.00
362_L	365_S	0.794	1.00
188_G	191_L	0.793	1.00
97_G	124_L	0.791	1.00
213_F	217_L	0.790	1.00
313_L	317_G	0.790	1.00
103_A	113_S	0.790	1.00
39_V	43_Y	0.789	1.00
69_S	73_A	0.788	1.00
24_M	193_A	0.788	1.00
380_V	384_L	0.788	1.00
42_G	46_D	0.786	1.00
86_V	138_W	0.781	1.00
308_K	312_L	0.781	1.00
171_V	254_A	0.781	1.00
75_R	340_A	0.778	1.00
187_M	191_L	0.777	1.00
293_I	297_L	0.777	1.00
47_V	179_L	0.776	1.00
62_Q	66_T	0.771	1.00
97_G	187_M	0.771	1.00
34_G	163_M	0.771	1.00
343_A	347_V	0.766	1.00
133_T	136_T	0.765	1.00
73_A	129_S	0.765	1.00
129_S	133_T	0.764	1.00
169_L	172_V	0.763	1.00
32_T	121_R	0.761	1.00
91_C	94_F	0.751	1.00
164_A	262_C	0.751	1.00
133_T	137_L	0.750	1.00
91_C	95_L	0.747	1.00
229_L	379_L	0.745	1.00
259_L	308_K	0.744	1.00
289_S	292_I	0.743	1.00
358_P	362_L	0.742	1.00
140_V	152_I	0.742	1.00
89_G	134_G	0.742	1.00
227_L	231_S	0.741	1.00
186_I	189_V	0.739	1.00
300_V	374_L	0.738	1.00
245_Y	307_A	0.738	1.00
267_T	271_F	0.736	1.00
68_L	71_P	0.735	1.00
59_I	239_T	0.733	1.00
32_T	186_I	0.733	1.00
86_V	197_A	0.732	1.00
283_V	286_I	0.729	1.00
372_I	375_A	0.723	1.00
58_V	114_L	0.721	1.00
130_F	134_G	0.720	1.00
165_M	168_P	0.720	1.00
327_V	331_K	0.719	1.00
163_M	261_S	0.718	1.00
28_A	32_T	0.714	1.00
121_R	124_L	0.714	1.00
23_V	154_W	0.712	1.00
53_F	56_G	0.712	1.00
236_V	376_A	0.711	1.00
270_L	274_G	0.710	1.00
368_G	371_V	0.710	1.00
152_I	330_V	0.709	1.00
359_L	362_L	0.709	1.00
230_A	321_V	0.707	1.00
100_Y	103_A	0.707	1.00
140_V	330_V	0.705	1.00
50_F	55_A	0.705	1.00
172_V	175_H	0.704	1.00
157_I	269_L	0.703	1.00
388_W	391_K	0.703	1.00
351_L	355_V	0.699	1.00
25_F	86_V	0.698	1.00
385_L	388_W	0.697	1.00
33_I	66_T	0.696	1.00
167_A	258_T	0.695	1.00
222_L	389_R	0.692	1.00
121_R	132_G	0.691	1.00
388_W	392_K	0.688	1.00
260_F	311_V	0.688	1.00
162_A	166_G	0.685	1.00
240_F	361_G	0.684	1.00
53_F	358_P	0.681	1.00
274_G	283_V	0.681	1.00
225_M	229_L	0.679	1.00
25_F	197_A	0.679	1.00
57_L	118_C	0.676	1.00
100_Y	124_L	0.675	1.00
64_F	67_L	0.675	1.00
138_W	142_V	0.672	1.00
379_L	383_A	0.670	1.00
221_W	224_G	0.668	1.00
146_L	150_R	0.668	1.00
243_L	246_D	0.666	1.00
43_Y	179_L	0.665	1.00
281_L	391_K	0.665	1.00
306_M	310_G	0.665	1.00
174_Y	182_L	0.665	1.00
19_I	151_V	0.664	1.00
90_L	193_A	0.664	1.00
98_L	184_L	0.664	1.00
256_A	308_K	0.661	1.00
389_R	392_K	0.659	1.00
259_L	263_A	0.658	1.00
93_C	128_Q	0.658	1.00
180_Q	184_L	0.657	1.00
288_F	321_V	0.656	1.00
95_L	98_L	0.656	1.00
157_I	265_V	0.655	1.00
26_N	155_N	0.655	1.00
52_A	247_A	0.652	1.00
27_F	165_M	0.652	1.00
148_I	330_V	0.651	1.00
94_F	98_L	0.651	1.00
73_A	76_Y	0.650	1.00
160_Y	265_V	0.650	1.00
310_G	313_L	0.649	1.00
67_L	350_D	0.649	1.00
31_L	186_I	0.649	1.00
35_L	182_L	0.649	1.00
250_W	304_P	0.646	1.00
382_I	386_L	0.645	1.00
181_A	188_G	0.645	1.00
212_P	337_N	0.640	1.00
185_I	188_G	0.640	1.00
200_R	204_K	0.639	1.00
291_E	317_G	0.638	1.00
171_V	255_F	0.638	1.00
56_G	361_G	0.637	1.00
308_K	311_V	0.634	1.00
99_G	103_A	0.634	1.00
297_L	301_A	0.634	1.00
287_C	324_A	0.632	1.00
171_V	258_T	0.631	1.00
77_A	85_I	0.631	1.00
17_L	20_V	0.627	1.00
157_I	160_Y	0.624	1.00
296_L	299_G	0.623	1.00
192_V	196_L	0.623	1.00
68_L	72_H	0.622	1.00
198_I	201_P	0.622	1.00
119_L	122_V	0.622	1.00
255_F	258_T	0.621	1.00
241_I	311_V	0.620	1.00
60_S	357_G	0.619	1.00
70_R	343_A	0.618	1.00
239_T	242_T	0.618	1.00
369_V	372_I	0.617	1.00
215_A	336_Q	0.614	1.00
225_M	228_A	0.612	1.00
54_W	58_V	0.612	1.00
224_G	345_Y	0.612	1.00
136_T	155_N	0.610	1.00
229_L	383_A	0.609	1.00
86_V	135_S	0.609	1.00
372_I	376_A	0.609	1.00
354_G	358_P	0.608	1.00
18_R	21_S	0.608	1.00
312_L	315_G	0.607	1.00
39_V	182_L	0.607	1.00
158_V	162_A	0.604	1.00
62_Q	121_R	0.603	1.00
271_F	274_G	0.603	1.00
149_G	327_V	0.599	1.00
100_Y	183_A	0.599	1.00
28_A	189_V	0.597	1.00
66_T	350_D	0.596	1.00
51_S	365_S	0.595	1.00
63_Y	357_G	0.594	1.00
213_F	216_V	0.594	1.00
330_V	338_Q	0.593	1.00
172_V	255_F	0.593	1.00
102_T	116_L	0.592	1.00
46_D	49_G	0.592	1.00
32_T	93_C	0.590	1.00
73_A	133_T	0.590	1.00
376_A	380_V	0.590	1.00
170_G	182_L	0.589	1.00
383_A	387_T	0.587	1.00
104_G	115_L	0.586	1.00
364_M	367_A	0.586	1.00
382_I	385_L	0.586	1.00
227_L	349_M	0.584	1.00
373_Y	377_A	0.584	1.00
240_F	243_L	0.584	1.00
355_V	359_L	0.582	1.00
27_F	158_V	0.580	1.00
384_L	388_W	0.579	1.00
291_E	294_G	0.578	1.00
21_S	193_A	0.578	1.00
224_G	228_A	0.574	1.00
233_G	236_V	0.573	1.00
267_T	319_S	0.571	1.00
364_M	372_I	0.569	1.00
139_G	151_V	0.569	1.00
54_W	115_L	0.566	1.00
141_G	203_V	0.564	1.00
274_G	277_R	0.560	1.00
26_N	30_Y	0.560	1.00
166_G	170_G	0.559	1.00
338_Q	342_L	0.557	1.00
192_V	195_L	0.557	1.00
168_P	171_V	0.556	1.00
285_M	387_T	0.554	1.00
269_L	272_P	0.554	1.00
194_I	198_I	0.553	1.00
259_L	312_L	0.551	1.00
240_F	360_A	0.549	1.00
120_G	123_I	0.546	1.00
371_V	378_G	0.545	1.00
70_R	347_V	0.544	1.00
299_G	370_P	0.544	1.00
49_G	52_A	0.543	1.00
326_G	330_V	0.542	1.00
339_G	343_A	0.542	1.00
368_G	372_I	0.540	1.00
360_A	372_I	0.540	1.00
157_I	161_G	0.539	1.00
173_F	176_W	0.538	1.00
212_P	218_G	0.537	1.00
225_M	386_L	0.534	1.00
364_M	369_V	0.534	1.00
90_L	197_A	0.533	1.00
178_G	182_L	0.532	1.00
87_V	90_L	0.531	1.00
281_L	392_K	0.530	1.00
261_S	265_V	0.530	1.00
387_T	392_K	0.530	1.00
172_V	177_G	0.529	1.00
156_G	160_Y	0.528	1.00
70_R	350_D	0.528	1.00
20_V	23_V	0.528	1.00
189_V	192_V	0.528	1.00
256_A	259_L	0.526	1.00
171_V	175_H	0.526	1.00
312_L	316_A	0.525	1.00
25_F	90_L	0.525	1.00
256_A	260_F	0.525	1.00
228_A	232_A	0.523	1.00
35_L	170_G	0.522	1.00
190_A	194_I	0.521	1.00
150_R	153_S	0.521	1.00
285_M	292_I	0.521	1.00
260_F	264_F	0.521	1.00
256_A	304_P	0.520	1.00
352_S	355_V	0.519	1.00
211_L	218_G	0.519	1.00
186_I	190_A	0.518	1.00
219_R	222_L	0.518	1.00
387_T	391_K	0.517	1.00
250_W	256_A	0.516	1.00
259_L	262_C	0.514	1.00
222_L	386_L	0.511	1.00
97_G	121_R	0.511	1.00
245_Y	256_A	0.510	1.00
246_D	252_G	0.510	1.00
73_A	85_I	0.509	1.00
137_L	339_G	0.509	1.00
386_L	389_R	0.506	1.00
284_A	325_L	0.506	1.00
369_V	373_Y	0.505	1.00
93_C	131_A	0.503	1.00
41_P	45_H	0.503	1.00
293_I	296_L	0.502	1.00
57_L	60_S	0.502	1.00
20_V	24_M	0.501	1.00
380_V	383_A	0.500	1.00
100_Y	121_R	0.500	1.00
378_G	385_L	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4j05A	3	0.9136	100	0.195	Contact Map
1pw4A	1	0.9654	100	0.198	Contact Map
4pypA	1	0.921	100	0.216	Contact Map
3wdoA	1	0.9556	100	0.239	Contact Map
4zw9A	1	0.9605	100	0.247	Contact Map
2cfqA	1	0.9679	100	0.258	Contact Map
3o7qA	1	0.9111	100	0.261	Contact Map
4ldsA	2	0.916	100	0.274	Contact Map
4gc0A	1	0.9531	100	0.277	Contact Map
4w6vA	1	0.9407	100	0.278	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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