XYLG - ECOLI - GREMLIN Contacts

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XYLG - Xylose import ATP-binding protein XylG

UniProt:	P37388	Sequences: MPYLLEMKNITKTFGSVKAIDNVCLRLNAGEIVSLCGENGSGKSTLMKVLCGIYPHGSYEGEIIFAGEEIQASHIRDTERKGIAIIHQELALVKELTVLENIFLGNEITHNGIMDYDLMTLRCQKLLAQVSLSISPDTRVGDLGLGQQQLVEIAKALNKQVRLLILDEPTASLTEQETSILLDIIRDLQQHGIACIYISHKLNEVKAISDTICVIRDGQHIGTRDAAGMSEDDIITMMVGRELTALYPNEPHTTGDEILRIEHLTAWHPVNRHIKRVNDVSFSLKRGEILGIAGLVGAGRTETIQCLFGVWPGQWEGKIYIDGKQVDIRNCQQAIAQGIAMVPEDRKRDGIVPVMAVGKNITLAALNKFTGGISQLDDAAEQKCILESIQQLKVKTSSPDLAIGRLSGGNQQKAILARCLLLNPRILILDEPTRGIDIGAKYEIYKLINQLVQQGIAVIVISSELPEVLGLSDRVLVMHEGKLKANLINHNLTQEQVMEAALRSEHHVEKQSV	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG12275
Length:	513 (473)
Sequences:	8695 (5836)
Seq/√Len:	268.3

ECOLI - XYLG MGLA ALSA YPHE YTFR ARAG LSRA RBSA YEJF MODF GSIA
BACSU - YUFO RBSA YKPA YFMM YKOD YFMR EXPZ
HALSA - Q9HR21
SULSO - Y2030 Y1893 Q97UG5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
62_E	69_E	3.580	1.00
31_E	211_T	3.562	1.00
21_D	219_Q	3.393	1.00
33_V	213_C	3.328	1.00
260_R	283_S	3.243	1.00
305_Q	311_W	3.213	1.00
120_T	137_D	3.178	1.00
14_F	54_Y	3.178	1.00
389_I	399_P	3.095	1.00
322_D	425_R	3.035	1.00
318_K	325_Q	2.949	1.00
34_S	209_S	2.948	1.00
66_A	162_R	2.861	1.00
9_N	22_N	2.813	1.00
262_E	318_K	2.786	1.00
304_I	461_I	2.780	1.00
263_H	279_D	2.743	1.00
118_L	122_R	2.727	1.00
124_Q	128_A	2.657	1.00
260_R	320_Y	2.636	1.00
222_G	237_M	2.590	1.00
186_R	207_A	2.570	1.00
257_E	260_R	2.563	1.00
6_E	26_R	2.534	1.00
32_I	185_I	2.464	1.00
72_A	81_K	2.443	1.00
8_K	62_E	2.390	1.00
389_I	396_T	2.358	1.00
13_T	18_K	2.335	1.00
138_T	142_D	2.327	1.00
209_S	226_A	2.304	1.00
6_E	64_I	2.303	1.00
7_M	10_I	2.298	1.00
122_R	125_K	2.268	1.00
352_V	363_L	2.261	1.00
256_D	286_R	2.258	1.00
303_T	478_M	2.204	1.00
460_V	471_L	2.148	1.00
476_L	486_N	2.126	1.00
450_Q	454_Q	2.122	1.00
225_D	228_G	2.114	1.00
18_K	21_D	2.101	1.00
257_E	283_S	2.077	1.00
387_E	391_Q	2.076	1.00
261_I	264_L	2.075	1.00
129_Q	191_H	2.069	1.00
47_M	198_I	2.035	1.00
179_S	207_A	2.027	1.00
11_T	18_K	2.025	1.00
388_S	417_A	1.973	1.00
290_L	476_L	1.960	1.00
236_T	242_E	1.928	1.00
425_R	456_I	1.925	1.00
86_I	166_L	1.924	1.00
115_D	118_L	1.895	1.00
9_N	24_C	1.864	1.00
304_I	428_I	1.858	1.00
261_I	282_F	1.846	1.00
278_N	482_K	1.815	1.00
436_I	444_I	1.806	1.00
230_S	233_D	1.797	1.00
47_M	85_I	1.797	1.00
262_E	320_Y	1.777	1.00
92_L	140_V	1.775	1.00
324_K	337_Q	1.754	1.00
93_V	104_L	1.731	1.00
289_I	448_I	1.728	1.00
284_L	457_A	1.721	1.00
429_L	448_I	1.715	1.00
73_S	77_D	1.714	1.00
11_T	22_N	1.708	1.00
65_F	163_L	1.689	1.00
4_L	194_A	1.689	1.00
258_I	457_A	1.687	1.00
257_E	285_K	1.684	1.00
321_I	326_V	1.683	1.00
362_T	381_E	1.681	1.00
75_I	78_T	1.672	1.00
291_G	472_S	1.655	1.00
293_A	468_V	1.647	1.00
10_I	49_V	1.634	1.00
13_T	60_E	1.625	1.00
358_G	400_D	1.606	1.00
7_M	50_L	1.605	1.00
357_V	396_T	1.599	1.00
386_L	390_Q	1.598	1.00
284_L	290_L	1.596	1.00
64_I	69_E	1.594	1.00
53_I	87_H	1.590	1.00
306_C	313_G	1.587	1.00
8_K	64_I	1.568	1.00
351_I	403_I	1.564	1.00
121_L	125_K	1.564	1.00
403_I	414_A	1.562	1.00
284_L	459_I	1.547	1.00
74_H	77_D	1.545	1.00
125_K	129_Q	1.534	1.00
321_I	426_I	1.534	1.00
186_R	189_Q	1.528	1.00
396_T	401_L	1.516	1.00
162_R	193_I	1.512	1.00
361_I	394_V	1.512	1.00
284_L	426_I	1.509	1.00
213_C	220_H	1.501	1.00
224_R	237_M	1.493	1.00
29_A	194_A	1.483	1.00
139_R	142_D	1.478	1.00
9_N	60_E	1.477	1.00
247_Y	470_G	1.475	1.00
377_D	380_A	1.464	1.00
305_Q	349_D	1.461	1.00
265_T	279_D	1.460	1.00
99_L	120_T	1.445	1.00
206_K	234_I	1.444	1.00
27_L	163_L	1.440	1.00
224_R	229_M	1.422	1.00
389_I	394_V	1.421	1.00
354_V	404_G	1.416	1.00
187_D	191_H	1.410	1.00
329_R	333_Q	1.394	1.00
68_E	81_K	1.387	1.00
95_E	141_G	1.381	1.00
233_D	236_T	1.378	1.00
118_L	121_L	1.375	1.00
100_E	116_Y	1.375	1.00
129_Q	187_D	1.371	1.00
376_L	381_E	1.370	1.00
124_Q	136_P	1.368	1.00
401_L	405_R	1.365	1.00
94_K	148_Q	1.360	1.00
345_D	348_R	1.351	1.00
266_A	277_V	1.346	1.00
182_L	208_I	1.346	1.00
282_F	476_L	1.341	1.00
33_V	223_T	1.335	1.00
189_Q	210_D	1.329	1.00
286_R	457_A	1.325	1.00
320_Y	325_Q	1.323	1.00
386_L	399_P	1.321	1.00
391_Q	450_Q	1.321	1.00
102_I	123_C	1.315	1.00
97_T	100_E	1.311	1.00
15_G	19_A	1.310	1.00
266_A	315_W	1.304	1.00
15_G	18_K	1.303	1.00
258_I	322_D	1.303	1.00
291_G	468_V	1.298	1.00
476_L	483_L	1.295	1.00
383_K	387_E	1.284	1.00
262_E	283_S	1.284	1.00
441_K	464_E	1.266	1.00
51_C	85_I	1.264	1.00
380_A	383_K	1.263	1.00
229_M	233_D	1.261	1.00
266_A	306_C	1.261	1.00
24_C	220_H	1.257	1.00
282_F	292_I	1.251	1.00
144_G	147_Q	1.246	1.00
113_I	375_Q	1.238	1.00
13_T	59_Y	1.236	1.00
135_S	138_T	1.235	1.00
357_V	414_A	1.235	1.00
254_T	285_K	1.230	1.00
397_S	401_L	1.228	1.00
286_R	425_R	1.225	1.00
72_A	77_D	1.224	1.00
74_H	78_T	1.213	1.00
126_L	158_N	1.210	1.00
77_D	80_R	1.207	1.00
292_I	476_L	1.199	1.00
257_E	286_R	1.197	1.00
275_K	278_N	1.197	1.00
26_R	211_T	1.196	1.00
99_L	136_P	1.195	1.00
263_H	281_S	1.195	1.00
277_V	306_C	1.193	1.00
203_N	231_E	1.190	1.00
11_T	60_E	1.187	1.00
212_I	226_A	1.187	1.00
36_C	202_L	1.182	1.00
468_V	472_S	1.176	1.00
342_V	429_L	1.175	1.00
382_Q	400_D	1.174	1.00
211_T	225_D	1.173	1.00
415_I	418_R	1.165	1.00
214_V	237_M	1.160	1.00
220_H	223_T	1.157	1.00
180_I	183_D	1.157	1.00
213_C	223_T	1.152	1.00
448_I	460_V	1.149	1.00
332_Q	336_A	1.147	1.00
185_I	195_C	1.147	1.00
267_W	315_W	1.145	1.00
301_T	344_E	1.144	1.00
356_A	359_K	1.144	1.00
288_E	474_R	1.143	1.00
290_L	459_I	1.140	1.00
263_H	316_E	1.138	1.00
355_M	359_K	1.135	1.00
102_I	158_N	1.130	1.00
267_W	275_K	1.129	1.00
468_V	475_V	1.128	1.00
166_L	195_C	1.122	1.00
185_I	208_I	1.122	1.00
402_A	405_R	1.118	1.00
23_V	215_I	1.113	1.00
89_E	434_R	1.104	1.00
282_F	290_L	1.104	1.00
187_D	190_Q	1.101	1.00
328_I	333_Q	1.101	1.00
98_V	134_I	1.097	1.00
279_D	482_K	1.096	1.00
387_E	390_Q	1.095	1.00
56_H	59_Y	1.092	1.00
343_P	349_D	1.091	1.00
206_K	230_S	1.090	1.00
450_Q	453_Q	1.086	1.00
388_S	394_V	1.083	1.00
224_R	233_D	1.083	1.00
428_I	461_I	1.073	1.00
224_R	228_G	1.072	1.00
29_A	162_R	1.072	1.00
398_S	401_L	1.059	1.00
277_V	280_V	1.058	1.00
330_N	333_Q	1.055	1.00
292_I	303_T	1.046	1.00
4_L	163_L	1.046	1.00
265_T	316_E	1.045	1.00
130_V	154_A	1.043	1.00
27_L	194_A	1.042	1.00
161_V	164_L	1.042	1.00
431_E	463_S	1.038	1.00
136_P	139_R	1.037	1.00
206_K	231_E	1.033	1.00
448_I	471_L	1.032	1.00
128_A	133_S	1.026	1.00
384_C	421_L	1.024	1.00
334_A	339_I	1.018	1.00
300_R	430_D	1.011	1.00
308_F	419_C	1.010	1.00
250_E	453_Q	1.005	1.00
328_I	334_A	1.002	1.00
423_N	454_Q	1.001	1.00
248_P	470_G	1.000	1.00
77_D	81_K	0.996	1.00
117_D	121_L	0.993	1.00
110_H	113_I	0.993	1.00
335_I	419_C	0.990	1.00
447_L	450_Q	0.985	1.00
361_I	385_I	0.984	1.00
397_S	405_R	0.983	1.00
292_I	459_I	0.983	1.00
5_L	50_L	0.982	1.00
423_N	456_I	0.982	1.00
89_E	347_K	0.979	1.00
186_R	190_Q	0.978	1.00
11_T	21_D	0.977	1.00
98_V	138_T	0.975	1.00
206_K	226_A	0.974	1.00
5_L	65_F	0.971	1.00
22_N	219_Q	0.970	1.00
353_P	403_I	0.969	1.00
266_A	276_R	0.966	1.00
108_I	119_M	0.966	1.00
257_E	262_E	0.966	1.00
48_K	54_Y	0.964	1.00
479_H	484_K	0.961	1.00
120_T	124_Q	0.959	1.00
4_L	65_F	0.958	1.00
233_D	237_M	0.958	1.00
385_I	399_P	0.957	1.00
125_K	128_A	0.956	1.00
358_G	399_P	0.955	1.00
290_L	486_N	0.953	1.00
369_F	384_C	0.950	1.00
70_I	81_K	0.946	1.00
84_A	161_V	0.943	1.00
358_G	381_E	0.939	1.00
185_I	197_Y	0.938	1.00
127_L	154_A	0.936	1.00
448_I	458_V	0.933	1.00
393_K	443_E	0.932	1.00
28_N	31_E	0.931	1.00
427_L	456_I	0.931	1.00
474_R	486_N	0.931	1.00
50_L	63_I	0.929	1.00
183_D	187_D	0.929	1.00
20_I	49_V	0.928	1.00
255_G	286_R	0.928	1.00
462_S	468_V	0.926	1.00
261_I	307_L	0.926	1.00
98_V	143_L	0.924	1.00
338_G	425_R	0.924	1.00
352_V	355_M	0.924	1.00
109_T	115_D	0.920	1.00
256_D	322_D	0.920	1.00
449_N	453_Q	0.919	1.00
56_H	71_Q	0.918	1.00
72_A	78_T	0.915	1.00
339_I	426_I	0.913	1.00
258_I	286_R	0.905	1.00
108_I	122_R	0.902	1.00
340_A	427_L	0.898	1.00
277_V	303_T	0.898	1.00
451_L	456_I	0.897	1.00
342_V	415_I	0.896	1.00
264_L	306_C	0.894	1.00
84_A	156_A	0.894	1.00
262_E	281_S	0.894	1.00
8_K	24_C	0.893	1.00
343_P	415_I	0.891	1.00
446_K	450_Q	0.889	1.00
371_G	374_S	0.889	1.00
63_I	72_A	0.886	1.00
4_L	66_A	0.876	1.00
358_G	382_Q	0.876	1.00
361_I	414_A	0.874	1.00
357_V	406_L	0.867	1.00
347_K	353_P	0.866	1.00
340_A	419_C	0.858	1.00
48_K	87_H	0.854	1.00
122_R	160_Q	0.853	1.00
28_N	211_T	0.849	1.00
301_T	430_D	0.847	1.00
164_L	195_C	0.846	1.00
179_S	183_D	0.846	1.00
49_V	56_H	0.846	1.00
79_E	159_K	0.844	1.00
99_L	108_I	0.843	1.00
261_I	319_I	0.834	0.99
340_A	424_P	0.834	0.99
205_V	226_A	0.831	0.99
396_T	406_L	0.830	0.99
264_L	313_G	0.826	0.99
296_V	463_S	0.826	0.99
331_C	334_A	0.825	0.99
379_A	383_K	0.825	0.99
123_C	136_P	0.824	0.99
386_L	389_I	0.820	0.99
364_A	419_C	0.819	0.99
22_N	60_E	0.819	0.99
32_I	189_Q	0.818	0.99
172_S	296_V	0.817	0.99
51_C	87_H	0.816	0.99
300_R	344_E	0.814	0.99
121_L	124_Q	0.813	0.99
328_I	339_I	0.813	0.99
108_I	114_M	0.813	0.99
234_I	240_G	0.813	0.99
469_L	475_V	0.812	0.99
29_A	66_A	0.810	0.99
212_I	224_R	0.809	0.99
27_L	196_I	0.806	0.99
361_I	417_A	0.805	0.99
358_G	385_I	0.805	0.99
428_I	459_I	0.804	0.99
99_L	119_M	0.799	0.99
289_I	449_N	0.798	0.99
362_T	366_L	0.797	0.99
238_M	241_R	0.796	0.99
103_F	119_M	0.796	0.99
368_K	423_N	0.795	0.99
236_T	240_G	0.794	0.99
13_T	19_A	0.794	0.99
124_Q	135_S	0.791	0.99
249_N	449_N	0.789	0.99
211_T	223_T	0.789	0.99
292_I	478_M	0.788	0.99
280_V	483_L	0.784	0.99
292_I	304_I	0.783	0.99
286_R	322_D	0.783	0.99
212_I	234_I	0.783	0.99
15_G	21_D	0.782	0.99
103_F	122_R	0.779	0.99
124_Q	137_D	0.779	0.99
234_I	238_M	0.775	0.99
106_N	159_K	0.772	0.99
152_E	155_K	0.771	0.99
65_F	70_I	0.769	0.99
206_K	229_M	0.767	0.99
359_K	381_E	0.767	0.99
164_L	193_I	0.766	0.99
350_G	415_I	0.764	0.99
333_Q	336_A	0.762	0.99
106_N	158_N	0.762	0.99
55_P	71_Q	0.760	0.99
388_S	421_L	0.757	0.99
90_L	145_L	0.756	0.99
100_E	107_E	0.756	0.99
347_K	411_Q	0.754	0.99
156_A	164_L	0.754	0.99
15_G	397_S	0.752	0.99
240_G	243_L	0.752	0.99
76_R	80_R	0.751	0.99
49_V	54_Y	0.751	0.99
166_L	185_I	0.750	0.99
46_L	215_I	0.748	0.99
225_D	229_M	0.748	0.99
7_M	25_L	0.745	0.99
266_A	275_K	0.744	0.99
365_A	368_K	0.743	0.99
132_L	150_L	0.735	0.99
32_I	186_R	0.734	0.99
126_L	154_A	0.731	0.99
260_R	318_K	0.730	0.99
308_F	428_I	0.730	0.99
26_R	223_T	0.727	0.99
351_I	411_Q	0.726	0.99
333_Q	337_Q	0.717	0.98
282_F	303_T	0.717	0.98
259_L	284_L	0.716	0.98
442_Y	446_K	0.715	0.98
12_K	59_Y	0.714	0.98
282_F	459_I	0.714	0.98
239_V	243_L	0.713	0.98
365_A	421_L	0.709	0.98
8_K	26_R	0.709	0.98
214_V	234_I	0.709	0.98
102_I	151_V	0.707	0.98
321_I	339_I	0.707	0.98
396_T	399_P	0.707	0.98
140_V	151_V	0.706	0.98
15_G	401_L	0.706	0.98
384_C	387_E	0.705	0.98
445_Y	470_G	0.704	0.98
23_V	220_H	0.703	0.98
160_Q	191_H	0.702	0.98
340_A	422_L	0.702	0.98
20_I	215_I	0.702	0.98
296_V	300_R	0.701	0.98
131_S	187_D	0.700	0.98
65_F	83_I	0.695	0.98
7_M	63_I	0.694	0.98
33_V	211_T	0.694	0.98
283_S	486_N	0.693	0.98
308_F	331_C	0.692	0.98
426_I	459_I	0.692	0.98
260_R	323_G	0.691	0.98
424_P	429_L	0.690	0.98
416_L	436_I	0.689	0.98
237_M	240_G	0.689	0.98
107_E	119_M	0.689	0.98
25_L	35_L	0.688	0.98
90_L	172_S	0.687	0.98
19_A	397_S	0.685	0.98
120_T	136_P	0.685	0.98
403_I	418_R	0.685	0.98
356_A	400_D	0.684	0.98
91_A	152_E	0.683	0.98
250_E	473_D	0.682	0.98
280_V	303_T	0.682	0.98
256_D	285_K	0.681	0.98
127_L	136_P	0.681	0.98
392_L	420_L	0.681	0.98
357_V	389_I	0.680	0.98
55_P	59_Y	0.680	0.98
328_I	337_Q	0.679	0.98
99_L	123_C	0.678	0.98
92_L	148_Q	0.677	0.98
241_R	247_Y	0.677	0.98
382_Q	399_P	0.675	0.98
353_P	404_G	0.675	0.98
353_P	418_R	0.674	0.98
75_I	79_E	0.673	0.98
109_T	112_G	0.673	0.98
306_C	311_W	0.673	0.98
319_I	328_I	0.672	0.98
38_E	241_R	0.672	0.98
97_T	139_R	0.672	0.98
84_A	159_K	0.671	0.98
87_H	91_A	0.670	0.98
28_N	225_D	0.669	0.98
313_G	327_D	0.668	0.98
266_A	311_W	0.668	0.98
126_L	130_V	0.666	0.97
92_L	151_V	0.666	0.97
110_H	115_D	0.662	0.97
449_N	473_D	0.661	0.97
95_E	139_R	0.660	0.97
304_I	341_M	0.659	0.97
382_Q	386_L	0.655	0.97
197_Y	208_I	0.655	0.97
424_P	456_I	0.655	0.97
265_T	277_V	0.654	0.97
202_L	205_V	0.654	0.97
7_M	165_I	0.654	0.97
127_L	132_L	0.654	0.97
90_L	152_E	0.653	0.97
341_M	349_D	0.652	0.97
356_A	402_A	0.652	0.97
394_V	417_A	0.652	0.97
372_G	377_D	0.651	0.97
264_L	319_I	0.648	0.97
416_L	444_I	0.647	0.97
108_I	115_D	0.644	0.97
5_L	163_L	0.644	0.97
203_N	207_A	0.640	0.97
47_M	165_I	0.639	0.97
123_C	127_L	0.639	0.97
143_L	151_V	0.639	0.97
27_L	33_V	0.639	0.97
401_L	404_G	0.638	0.97
48_K	53_I	0.637	0.97
25_L	33_V	0.637	0.97
258_I	426_I	0.636	0.97
424_P	427_L	0.635	0.97
90_L	171_A	0.635	0.97
17_V	397_S	0.634	0.97
380_A	384_C	0.633	0.97
189_Q	195_C	0.631	0.97
120_T	123_C	0.630	0.96
6_E	67_G	0.629	0.96
199_S	205_V	0.627	0.96
289_I	471_L	0.627	0.96
308_F	335_I	0.627	0.96
124_Q	133_S	0.625	0.96
326_V	337_Q	0.624	0.96
259_L	264_L	0.622	0.96
321_I	337_Q	0.621	0.96
34_S	226_A	0.621	0.96
477_V	484_K	0.620	0.96
25_L	196_I	0.619	0.96
99_L	137_D	0.619	0.96
357_V	403_I	0.618	0.96
28_N	194_A	0.618	0.96
174_T	178_T	0.617	0.96
286_R	290_L	0.617	0.96
258_I	284_L	0.617	0.96
102_I	126_L	0.617	0.96
108_I	118_L	0.616	0.96
255_G	285_K	0.613	0.96
35_L	196_I	0.613	0.96
390_Q	393_K	0.612	0.96
293_A	465_L	0.611	0.96
436_I	447_L	0.611	0.96
197_Y	201_K	0.610	0.96
416_L	429_L	0.610	0.96
342_V	416_L	0.607	0.96
72_A	83_I	0.607	0.96
184_I	187_D	0.605	0.96
371_G	377_D	0.605	0.96
178_T	208_I	0.605	0.96
292_I	483_L	0.604	0.96
283_S	320_Y	0.604	0.96
13_T	21_D	0.603	0.95
478_M	483_L	0.601	0.95
451_L	458_V	0.600	0.95
89_E	152_E	0.599	0.95
44_S	48_K	0.599	0.95
174_T	177_E	0.599	0.95
303_T	307_L	0.598	0.95
252_H	255_G	0.598	0.95
452_V	458_V	0.596	0.95
98_V	136_P	0.595	0.95
252_H	453_Q	0.593	0.95
76_R	79_E	0.592	0.95
7_M	24_C	0.591	0.95
197_Y	205_V	0.591	0.95
163_L	194_A	0.591	0.95
362_T	384_C	0.590	0.95
259_L	263_H	0.590	0.95
206_K	209_S	0.588	0.95
411_Q	463_S	0.588	0.95
113_I	116_Y	0.586	0.95
188_L	195_C	0.586	0.95
209_S	212_I	0.586	0.95
329_R	334_A	0.586	0.95
129_Q	160_Q	0.585	0.95
4_L	29_A	0.585	0.95
280_V	478_M	0.584	0.95
241_R	466_P	0.583	0.95
392_L	417_A	0.583	0.95
215_I	220_H	0.583	0.95
383_K	386_L	0.582	0.95
25_L	194_A	0.581	0.94
186_R	208_I	0.580	0.94
122_R	126_L	0.578	0.94
145_L	171_A	0.578	0.94
149_Q	152_E	0.577	0.94
249_N	473_D	0.576	0.94
403_I	415_I	0.576	0.94
300_R	463_S	0.576	0.94
31_E	194_A	0.574	0.94
451_L	454_Q	0.573	0.94
202_L	234_I	0.573	0.94
391_Q	447_L	0.572	0.94
305_Q	310_V	0.572	0.94
123_C	126_L	0.571	0.94
452_V	457_A	0.571	0.94
445_Y	449_N	0.569	0.94
364_A	422_L	0.569	0.94
126_L	129_Q	0.568	0.94
217_D	395_K	0.568	0.94
245_A	248_P	0.567	0.94
306_C	312_P	0.566	0.94
145_L	434_R	0.566	0.94
171_A	434_R	0.565	0.94
254_T	257_E	0.565	0.94
235_I	240_G	0.564	0.94
350_G	418_R	0.564	0.94
146_G	296_V	0.564	0.94
304_I	430_D	0.563	0.94
65_F	81_K	0.562	0.93
385_I	389_I	0.561	0.93
174_T	296_V	0.561	0.93
290_L	457_A	0.560	0.93
257_E	320_Y	0.560	0.93
266_A	313_G	0.559	0.93
460_V	472_S	0.557	0.93
335_I	364_A	0.556	0.93
141_G	148_Q	0.556	0.93
259_L	426_I	0.555	0.93
265_T	278_N	0.554	0.93
26_R	64_I	0.554	0.93
143_L	147_Q	0.554	0.93
19_A	215_I	0.553	0.93
308_F	340_A	0.553	0.93
189_Q	208_I	0.553	0.93
103_F	123_C	0.551	0.93
357_V	401_L	0.551	0.93
178_T	201_K	0.551	0.93
98_V	151_V	0.550	0.93
226_A	229_M	0.550	0.93
116_Y	119_M	0.549	0.93
365_A	422_L	0.549	0.93
370_T	375_Q	0.548	0.93
235_I	238_M	0.547	0.93
416_L	420_L	0.547	0.93
199_S	463_S	0.546	0.92
120_T	135_S	0.545	0.92
130_V	150_L	0.544	0.92
171_A	201_K	0.543	0.92
232_D	242_E	0.543	0.92
131_S	183_D	0.543	0.92
183_D	207_A	0.542	0.92
265_T	275_K	0.541	0.92
388_S	392_L	0.541	0.92
321_I	328_I	0.540	0.92
152_E	434_R	0.540	0.92
360_N	363_L	0.540	0.92
304_I	459_I	0.539	0.92
182_L	189_Q	0.539	0.92
145_L	148_Q	0.539	0.92
241_R	439_G	0.535	0.92
205_V	209_S	0.535	0.92
38_E	238_M	0.535	0.92
101_N	140_V	0.535	0.92
169_P	177_E	0.535	0.92
49_V	59_Y	0.534	0.92
378_D	381_E	0.533	0.92
319_I	326_V	0.533	0.92
216_R	221_I	0.532	0.92
395_K	401_L	0.532	0.92
264_L	303_T	0.532	0.92
106_N	122_R	0.531	0.91
357_V	405_R	0.528	0.91
138_T	143_L	0.528	0.91
127_L	130_V	0.527	0.91
259_L	262_E	0.527	0.91
445_Y	471_L	0.526	0.91
135_S	139_R	0.525	0.91
33_V	196_I	0.525	0.91
357_V	397_S	0.525	0.91
50_L	165_I	0.524	0.91
203_N	464_E	0.524	0.91
33_V	194_A	0.524	0.91
116_Y	120_T	0.524	0.91
293_A	462_S	0.523	0.91
134_I	138_T	0.523	0.91
379_A	382_Q	0.522	0.91
13_T	16_S	0.520	0.91
449_N	471_L	0.519	0.90
231_E	234_I	0.519	0.90
300_R	431_E	0.519	0.90
343_P	348_R	0.519	0.90
181_L	185_I	0.519	0.90
7_M	49_V	0.518	0.90
308_F	341_M	0.517	0.90
448_I	452_V	0.517	0.90
138_T	147_Q	0.516	0.90
133_S	147_Q	0.516	0.90
4_L	28_N	0.516	0.90
85_I	90_L	0.515	0.90
388_S	391_Q	0.515	0.90
117_D	379_A	0.514	0.90
396_T	405_R	0.514	0.90
36_C	212_I	0.513	0.90
255_G	259_L	0.513	0.90
165_I	198_I	0.513	0.90
47_M	50_L	0.512	0.90
32_I	208_I	0.511	0.90
94_K	141_G	0.510	0.90
392_L	447_L	0.509	0.90
131_S	180_I	0.508	0.90
263_H	318_K	0.508	0.90
365_A	369_F	0.507	0.89
36_C	205_V	0.507	0.89
109_T	113_I	0.505	0.89
90_L	140_V	0.505	0.89
483_L	486_N	0.505	0.89
70_I	73_S	0.505	0.89
35_L	47_M	0.504	0.89
290_L	483_L	0.504	0.89
343_P	350_G	0.504	0.89
351_I	414_A	0.502	0.89
442_Y	470_G	0.502	0.89
232_D	236_T	0.501	0.89
214_V	222_G	0.501	0.89
261_I	313_G	0.500	0.89
20_I	23_V	0.500	0.89

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4q9hA	1	0.9532	100	0.374	Contact Map
4finA	2	0.8986	100	0.394	Contact Map
4f4cA	1	0.9279	100	0.399	Contact Map
1yqtA	1	0.8967	100	0.429	Contact Map
3ux8A	2	0.8382	100	0.433	Contact Map
3bk7A	1	0.9103	100	0.441	Contact Map
3ozxA	1	0.883	100	0.442	Contact Map
2iw3A	2	0.883	100	0.446	Contact Map
3j16B	1	0.9123	100	0.455	Contact Map
2vf7A	2	0.9376	100	0.529	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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