MENE - ECOLI - GREMLIN Contacts

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MENE - 2-succinylbenzoate--CoA ligase

UniProt:	P37353	Sequences: MIFSDWPWRHWRQVRGETIALRLNDEQLNWRELCARVDELASGFAVQGVVEGSGVMLRAWNTPQTLLAWLALLQCGARVLPVNPQLPQPLLEELLPNLTLQFALVPDGENTFPALTSLHIQLVEGAHAATWQPTRLCSMTLTSGSTGLPKAAVHTYQAHLASAQGVLSLIPFGDHDDWLLSLPLFHVSGQGIMWRWLYAGARMTVRDKQPLEQMLAGCTHASLVPTQLWRLLVNRSSVSLKAVLLGGAAIPVELTEQAREQGIRCFCGYGLTEFASTVCAKEADGLADVGSPLPGREVKIVNNEVWLRAASMAEGYWRNGQLVSLVNDEGWYATRDRGEMHNGKLTIVGRLDNLFFSGGEGIQPEEVERVIAAHPAVLQVFIVPVADKEFGHRPVAVMEYDHESVDLSEWVKDKLARFQQPVRWLTLPPELKNGGIKISRQALKEWVQRQQ	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG12437
Length:	451 (432)
Sequences:	70450 (49543)
Seq/√Len:	2383.6

ECOLI - MENE ENTF AAS ACSA LCFA FADK ENTE PRPE CAIC PAAK
BACSU - PPSE SRFAC MENE YDAB LCFB ACSA LCFA DHBE YNGI YHFT DLTA PPSB PPSC YTCI DHBF PKSJ PPSD SRFAA SRFAB PPSA
HALSA - Q9HRY8 Q9HQU8 Q9HSM3 Q9HQ43 Q9HQN8 Q9HNK0
SULSO - Q97UX8 Q97VT6 Q97UW7 Q97U22 Q97WQ0 Q97WK0 Q97YK9 Q97VU7 Q97WQ9 Q97XW4 Q97V27 Q97UF6 Q97WS5 Q980E4 Q97X52 Q97XW5 Q97VJ6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
136_L	153_V	3.864	1.00
374_H	410_W	3.081	1.00
305_V	338_G	3.049	1.00
38_D	74_Q	2.894	1.00
97_N	141_L	2.863	1.00
319_N	322_L	2.839	1.00
297_E	308_R	2.802	1.00
339_E	346_T	2.727	1.00
155_T	314_E	2.722	1.00
53_S	101_Q	2.721	1.00
34_C	74_Q	2.695	1.00
56_M	100_L	2.680	1.00
49_V	77_A	2.652	1.00
22_R	202_R	2.532	1.00
356_F	361_G	2.514	1.00
304_E	333_A	2.452	1.00
19_I	27_Q	2.389	1.00
177_D	202_R	2.374	1.00
379_Q	432_K	2.335	1.00
43_G	47_Q	2.329	1.00
54_G	80_L	2.328	1.00
301_V	306_W	2.301	1.00
99_T	318_R	2.254	1.00
15_R	18_T	2.249	1.00
371_I	396_A	2.247	1.00
9_R	34_C	2.218	1.00
372_A	380_V	2.214	1.00
36_R	67_L	2.143	1.00
341_H	346_T	2.113	1.00
11_W	15_R	2.112	1.00
97_N	319_N	2.105	1.00
306_W	333_A	2.090	1.00
68_A	104_L	2.082	1.00
93_E	148_L	2.064	1.00
23_L	63_P	2.044	1.00
353_N	440_R	2.033	1.00
34_C	38_D	2.027	1.00
395_V	425_L	2.027	1.00
439_S	442_A	1.987	1.00
72_L	77_A	1.986	1.00
341_H	344_K	1.966	1.00
288_D	346_T	1.965	1.00
132_Q	135_R	1.939	1.00
176_D	241_K	1.930	1.00
373_A	414_K	1.927	1.00
176_D	219_T	1.894	1.00
40_L	67_L	1.879	1.00
339_E	348_V	1.847	1.00
320_G	324_S	1.840	1.00
366_E	419_Q	1.827	1.00
51_E	135_R	1.789	1.00
252_V	256_E	1.789	1.00
17_E	31_R	1.779	1.00
299_K	306_W	1.767	1.00
92_E	96_P	1.764	1.00
50_V	53_S	1.759	1.00
52_G	135_R	1.752	1.00
340_M	345_L	1.727	1.00
45_A	75_C	1.726	1.00
37_V	74_Q	1.722	1.00
22_R	27_Q	1.722	1.00
378_L	401_D	1.698	1.00
442_A	445_E	1.673	1.00
372_A	379_Q	1.660	1.00
66_L	193_M	1.653	1.00
204_T	218_C	1.651	1.00
155_T	158_A	1.649	1.00
10_H	14_V	1.648	1.00
60_W	106_P	1.644	1.00
368_E	382_I	1.636	1.00
38_D	42_S	1.634	1.00
397_V	443_L	1.629	1.00
31_R	35_A	1.622	1.00
383_V	397_V	1.618	1.00
56_M	82_V	1.586	1.00
223_L	228_L	1.568	1.00
211_L	215_L	1.557	1.00
136_L	314_E	1.550	1.00
73_L	137_C	1.544	1.00
217_G	239_S	1.541	1.00
29_N	32_E	1.529	1.00
141_L	151_A	1.525	1.00
400_Y	426_T	1.508	1.00
399_E	430_E	1.504	1.00
211_L	214_M	1.502	1.00
11_W	14_V	1.501	1.00
398_M	426_T	1.500	1.00
382_I	396_A	1.498	1.00
357_S	362_I	1.490	1.00
19_I	22_R	1.483	1.00
264_R	282_E	1.480	1.00
28_L	67_L	1.476	1.00
397_V	444_K	1.473	1.00
54_G	78_R	1.470	1.00
325_L	328_D	1.462	1.00
278_V	307_L	1.460	1.00
196_W	201_A	1.457	1.00
167_L	199_A	1.457	1.00
300_I	338_G	1.451	1.00
256_E	260_E	1.451	1.00
376_A	406_D	1.451	1.00
134_T	157_Q	1.436	1.00
433_N	439_S	1.425	1.00
16_G	31_R	1.421	1.00
338_G	347_I	1.421	1.00
226_T	248_A	1.420	1.00
285_G	342_N	1.419	1.00
98_L	141_L	1.407	1.00
228_L	243_V	1.406	1.00
9_R	74_Q	1.405	1.00
168_S	294_P	1.403	1.00
271_L	332_Y	1.402	1.00
19_I	202_R	1.402	1.00
370_V	414_K	1.397	1.00
55_V	72_L	1.395	1.00
139_M	317_W	1.395	1.00
158_A	275_A	1.393	1.00
12_R	34_C	1.393	1.00
18_T	175_H	1.393	1.00
410_W	414_K	1.391	1.00
179_L	218_C	1.387	1.00
153_V	317_W	1.373	1.00
212_E	215_L	1.373	1.00
28_L	63_P	1.366	1.00
20_A	33_L	1.362	1.00
153_V	315_G	1.362	1.00
173_G	176_D	1.360	1.00
176_D	220_H	1.355	1.00
386_A	392_H	1.354	1.00
408_S	424_W	1.352	1.00
398_M	424_W	1.351	1.00
308_R	331_W	1.348	1.00
95_L	100_L	1.341	1.00
279_C	298_V	1.321	1.00
177_D	204_T	1.317	1.00
55_V	77_A	1.316	1.00
298_V	307_L	1.309	1.00
52_G	314_E	1.309	1.00
337_R	351_L	1.305	1.00
23_L	26_E	1.304	1.00
409_E	413_D	1.298	1.00
97_N	318_R	1.288	1.00
291_S	344_K	1.284	1.00
397_V	427_L	1.280	1.00
80_L	98_L	1.272	1.00
285_G	344_K	1.269	1.00
56_M	95_L	1.265	1.00
54_G	139_M	1.265	1.00
387_D	393_R	1.263	1.00
49_V	53_S	1.260	1.00
299_K	331_W	1.256	1.00
133_P	157_Q	1.256	1.00
355_F	364_P	1.255	1.00
70_L	197_L	1.253	1.00
54_G	317_W	1.250	1.00
101_Q	116_T	1.240	1.00
379_Q	399_E	1.234	1.00
353_N	365_E	1.232	1.00
408_S	412_K	1.228	1.00
245_L	250_I	1.228	1.00
292_P	298_V	1.224	1.00
395_V	423_R	1.211	1.00
412_K	420_Q	1.206	1.00
385_V	395_V	1.205	1.00
403_E	406_D	1.204	1.00
93_E	97_N	1.202	1.00
305_V	347_I	1.201	1.00
71_A	75_C	1.199	1.00
78_R	136_L	1.198	1.00
410_W	413_D	1.197	1.00
57_L	68_A	1.196	1.00
49_V	55_V	1.190	1.00
157_Q	310_A	1.187	1.00
97_N	148_L	1.183	1.00
304_E	351_L	1.182	1.00
365_E	369_R	1.179	1.00
139_M	151_A	1.168	1.00
177_D	218_C	1.162	1.00
281_K	344_K	1.158	1.00
188_S	222_S	1.158	1.00
33_L	70_L	1.156	1.00
142_T	152_A	1.151	1.00
221_A	240_L	1.150	1.00
153_V	314_E	1.150	1.00
88_Q	92_E	1.148	1.00
36_R	39_E	1.143	1.00
412_K	417_R	1.142	1.00
35_A	39_E	1.141	1.00
360_E	418_F	1.136	1.00
393_R	422_V	1.133	1.00
233_V	257_Q	1.121	1.00
154_H	158_A	1.121	1.00
384_P	392_H	1.116	1.00
96_P	148_L	1.116	1.00
131_W	135_R	1.108	1.00
354_L	363_Q	1.103	1.00
40_L	71_A	1.101	1.00
28_L	36_R	1.097	1.00
396_A	424_W	1.094	1.00
220_H	242_A	1.090	1.00
58_R	91_L	1.090	1.00
9_R	38_D	1.087	1.00
411_V	420_Q	1.086	1.00
43_G	46_V	1.084	1.00
22_R	204_T	1.082	1.00
393_R	423_R	1.077	1.00
90_L	419_Q	1.076	1.00
404_S	424_W	1.075	1.00
232_L	257_Q	1.073	1.00
20_A	30_W	1.071	1.00
32_E	35_A	1.064	1.00
134_T	155_T	1.063	1.00
65_T	184_L	1.063	1.00
229_W	254_L	1.060	1.00
36_R	64_Q	1.060	1.00
404_S	426_T	1.059	1.00
319_N	323_V	1.056	1.00
281_K	288_D	1.054	1.00
40_L	104_L	1.054	1.00
26_E	63_P	1.049	1.00
327_N	333_A	1.047	1.00
41_A	74_Q	1.045	1.00
358_G	390_F	1.043	1.00
296_R	311_S	1.038	1.00
289_V	347_I	1.035	1.00
33_L	67_L	1.032	1.00
306_W	331_W	1.028	1.00
143_S	435_G	1.025	1.00
251_P	254_L	1.021	1.00
161_A	295_G	1.012	1.00
405_V	409_E	1.009	1.00
427_L	430_E	1.008	1.00
177_D	219_T	1.005	1.00
406_D	409_E	1.001	1.00
385_V	423_R	1.001	1.00
176_D	201_A	0.998	1.00
140_T	272_T	0.994	1.00
178_W	196_W	0.994	1.00
82_V	91_L	0.994	1.00
416_A	419_Q	0.993	1.00
182_L	188_S	0.990	1.00
378_L	399_E	0.985	1.00
93_E	141_L	0.982	1.00
49_V	102_F	0.981	1.00
37_V	71_A	0.981	1.00
18_T	202_R	0.978	1.00
213_Q	216_A	0.977	1.00
24_N	207_D	0.976	1.00
355_F	394_P	0.976	1.00
374_H	407_L	0.972	1.00
212_E	216_A	0.971	1.00
152_A	313_A	0.971	1.00
430_E	438_I	0.970	1.00
161_A	310_A	0.966	1.00
309_A	312_M	0.964	1.00
83_N	185_F	0.964	1.00
308_R	329_E	0.962	1.00
370_V	373_A	0.960	1.00
288_D	344_K	0.957	1.00
158_A	312_M	0.957	1.00
368_E	440_R	0.955	1.00
40_L	68_A	0.953	1.00
53_S	77_A	0.950	1.00
28_L	33_L	0.950	1.00
230_R	389_E	0.948	1.00
89_P	414_K	0.947	1.00
441_Q	445_E	0.947	1.00
279_C	345_L	0.943	1.00
44_F	72_L	0.942	1.00
298_V	345_L	0.941	1.00
179_L	206_R	0.934	1.00
307_L	334_T	0.934	1.00
370_V	411_V	0.933	1.00
59_A	62_T	0.929	1.00
285_G	341_H	0.925	1.00
253_E	257_Q	0.924	1.00
162_S	276_S	0.921	1.00
337_R	349_G	0.920	1.00
381_F	430_E	0.919	1.00
54_G	99_T	0.919	1.00
404_S	408_S	0.918	1.00
26_E	36_R	0.916	1.00
229_W	251_P	0.913	1.00
86_L	94_L	0.912	1.00
33_L	37_V	0.912	1.00
21_L	66_L	0.905	1.00
250_I	255_T	0.904	1.00
373_A	410_W	0.903	1.00
93_E	96_P	0.903	1.00
56_M	103_A	0.903	1.00
357_S	422_V	0.902	1.00
8_W	12_R	0.900	1.00
42_S	45_A	0.896	1.00
228_L	258_A	0.893	1.00
89_P	93_E	0.890	1.00
63_P	67_L	0.881	1.00
163_A	198_Y	0.879	1.00
409_E	412_K	0.878	1.00
374_H	406_D	0.876	1.00
69_W	190_Q	0.874	1.00
242_A	266_F	0.873	1.00
57_L	79_V	0.871	1.00
69_W	79_V	0.870	1.00
406_D	410_W	0.870	1.00
89_P	92_E	0.869	1.00
137_C	156_Y	0.869	1.00
222_S	277_T	0.868	1.00
244_L	268_G	0.868	1.00
300_I	345_L	0.868	1.00
298_V	305_V	0.868	1.00
93_E	319_N	0.867	1.00
34_C	37_V	0.867	1.00
357_S	384_P	0.867	1.00
22_R	177_D	0.860	1.00
240_L	243_V	0.857	1.00
154_H	275_A	0.857	1.00
187_V	271_L	0.855	1.00
407_L	424_W	0.851	1.00
72_L	79_V	0.850	1.00
64_Q	67_L	0.849	1.00
196_W	203_M	0.847	1.00
154_H	313_A	0.846	1.00
376_A	401_D	0.845	1.00
187_V	276_S	0.844	1.00
209_Q	227_Q	0.838	1.00
41_A	75_C	0.837	1.00
60_W	108_G	0.828	1.00
32_E	36_R	0.825	1.00
257_Q	260_E	0.824	1.00
386_A	389_E	0.824	1.00
45_A	50_V	0.823	1.00
36_R	63_P	0.823	1.00
49_V	75_C	0.822	1.00
322_L	325_L	0.815	1.00
175_H	219_T	0.813	1.00
44_F	104_L	0.812	1.00
21_L	63_P	0.811	1.00
39_E	43_G	0.810	1.00
56_M	80_L	0.809	1.00
10_H	13_Q	0.809	1.00
181_S	227_Q	0.806	1.00
224_V	227_Q	0.802	1.00
19_I	29_N	0.801	1.00
228_L	245_L	0.799	1.00
308_R	330_G	0.798	1.00
206_R	214_M	0.796	1.00
7_P	164_Q	0.795	1.00
216_A	235_R	0.795	1.00
381_F	443_L	0.792	1.00
66_L	205_V	0.791	1.00
305_V	345_L	0.788	1.00
378_L	400_Y	0.787	1.00
136_L	155_T	0.786	1.00
327_N	330_G	0.786	1.00
376_A	400_Y	0.784	1.00
274_F	332_Y	0.783	1.00
328_D	333_A	0.782	1.00
7_P	11_W	0.780	1.00
8_W	70_L	0.780	1.00
242_A	264_R	0.779	1.00
326_V	331_W	0.779	1.00
177_D	217_G	0.777	1.00
274_F	312_M	0.776	1.00
33_L	66_L	0.775	1.00
321_Q	324_S	0.774	1.00
235_R	238_V	0.773	1.00
19_I	23_L	0.768	1.00
9_R	13_Q	0.767	1.00
18_T	174_D	0.764	1.00
353_N	368_E	0.762	1.00
6_W	9_R	0.761	1.00
320_G	323_V	0.754	1.00
219_T	241_K	0.753	1.00
72_L	75_C	0.752	1.00
274_F	307_L	0.752	1.00
131_W	156_Y	0.752	1.00
94_L	151_A	0.752	1.00
229_W	257_Q	0.752	1.00
297_E	331_W	0.751	1.00
80_L	100_L	0.750	1.00
6_W	10_H	0.750	1.00
26_E	64_Q	0.748	1.00
67_L	71_A	0.748	1.00
408_S	420_Q	0.748	1.00
333_A	351_L	0.745	1.00
188_S	246_G	0.745	1.00
399_E	429_P	0.745	1.00
162_S	275_A	0.743	1.00
115_L	118_L	0.742	1.00
69_W	73_L	0.741	1.00
253_E	256_E	0.736	1.00
15_R	31_R	0.736	1.00
191_G	222_S	0.735	1.00
298_V	338_G	0.733	1.00
386_A	390_F	0.728	1.00
47_Q	102_F	0.728	1.00
299_K	308_R	0.725	1.00
58_R	103_A	0.723	1.00
338_G	345_L	0.721	1.00
59_A	65_T	0.721	1.00
381_F	438_I	0.719	1.00
229_W	233_V	0.716	1.00
364_P	382_I	0.714	1.00
137_C	159_H	0.713	1.00
162_S	191_G	0.707	1.00
186_H	360_E	0.706	1.00
267_C	287_A	0.706	1.00
138_S	154_H	0.706	1.00
79_V	190_Q	0.704	1.00
172_F	176_D	0.704	1.00
62_T	106_P	0.703	1.00
212_E	234_N	0.702	1.00
274_F	278_V	0.701	1.00
169_L	294_P	0.701	1.00
411_V	415_L	0.701	1.00
50_V	77_A	0.700	1.00
386_A	391_G	0.699	1.00
167_L	195_R	0.696	1.00
338_G	348_V	0.695	1.00
222_S	268_G	0.694	1.00
8_W	34_C	0.693	1.00
68_A	72_L	0.692	1.00
268_G	277_T	0.691	1.00
87_P	90_L	0.689	1.00
172_F	220_H	0.689	1.00
40_L	44_F	0.688	1.00
370_V	410_W	0.687	1.00
42_S	127_H	0.686	1.00
266_F	282_E	0.684	1.00
41_A	71_A	0.682	1.00
89_P	148_L	0.680	1.00
45_A	129_A	0.679	1.00
181_S	224_V	0.679	1.00
385_V	393_R	0.677	1.00
243_V	258_A	0.675	1.00
250_I	265_C	0.675	1.00
306_W	327_N	0.675	1.00
69_W	194_W	0.675	1.00
383_V	444_K	0.674	1.00
178_W	220_H	0.673	1.00
300_I	340_M	0.673	1.00
17_E	29_N	0.672	1.00
113_P	116_T	0.672	1.00
293_L	296_R	0.672	1.00
40_L	43_G	0.672	1.00
56_M	98_L	0.671	1.00
269_Y	278_V	0.669	1.00
357_S	390_F	0.669	1.00
417_R	420_Q	0.667	1.00
328_D	331_W	0.667	1.00
364_P	440_R	0.666	1.00
59_A	68_A	0.666	1.00
59_A	104_L	0.666	1.00
371_I	380_V	0.664	1.00
387_D	390_F	0.662	1.00
173_G	241_K	0.661	1.00
326_V	332_Y	0.661	1.00
381_F	440_R	0.660	1.00
431_L	443_L	0.660	1.00
210_P	213_Q	0.659	1.00
45_A	128_A	0.658	1.00
48_G	77_A	0.658	1.00
27_Q	202_R	0.657	1.00
397_V	425_L	0.657	1.00
55_V	102_F	0.655	1.00
46_V	121_Q	0.648	1.00
312_M	332_Y	0.648	1.00
11_W	200_G	0.647	1.00
12_R	16_G	0.647	1.00
162_S	277_T	0.645	1.00
357_S	394_P	0.645	1.00
229_W	253_E	0.644	1.00
99_T	317_W	0.643	1.00
365_E	368_E	0.643	1.00
39_E	42_S	0.640	1.00
377_V	398_M	0.640	1.00
158_A	314_E	0.636	1.00
37_V	41_A	0.635	1.00
364_P	384_P	0.634	1.00
301_V	331_W	0.634	1.00
38_D	45_A	0.633	1.00
249_A	347_I	0.633	1.00
183_P	186_H	0.631	1.00
378_L	402_H	0.631	1.00
134_T	314_E	0.630	1.00
23_L	207_D	0.629	1.00
50_V	101_Q	0.628	1.00
30_W	201_A	0.628	1.00
271_L	334_T	0.626	1.00
243_V	263_I	0.626	1.00
191_G	277_T	0.625	1.00
300_I	305_V	0.625	1.00
70_L	194_W	0.625	1.00
37_V	40_L	0.624	1.00
51_E	129_A	0.624	1.00
97_N	317_W	0.624	1.00
377_V	380_V	0.623	1.00
191_G	276_S	0.622	1.00
182_L	222_S	0.621	1.00
185_F	360_E	0.616	1.00
172_F	201_A	0.616	1.00
299_K	328_D	0.616	1.00
352_D	392_H	0.614	1.00
13_Q	34_C	0.613	1.00
64_Q	106_P	0.613	1.00
115_L	119_H	0.612	1.00
221_A	243_V	0.611	1.00
21_L	203_M	0.610	1.00
28_L	32_E	0.609	1.00
297_E	328_D	0.608	1.00
114_A	117_S	0.607	1.00
138_S	159_H	0.606	1.00
271_L	274_F	0.606	1.00
392_H	444_K	0.605	1.00
163_A	194_W	0.603	1.00
19_I	177_D	0.601	1.00
59_A	106_P	0.601	1.00
51_E	131_W	0.601	1.00
80_L	141_L	0.600	1.00
192_I	222_S	0.598	1.00
138_S	190_Q	0.598	1.00
408_S	411_V	0.598	1.00
59_A	105_V	0.597	1.00
54_G	318_R	0.597	1.00
398_M	407_L	0.595	1.00
325_L	332_Y	0.595	1.00
164_Q	198_Y	0.595	1.00
44_F	102_F	0.594	1.00
356_F	363_Q	0.591	1.00
297_E	329_E	0.591	1.00
257_Q	261_Q	0.589	1.00
78_R	139_M	0.585	1.00
250_I	267_C	0.584	1.00
404_S	423_R	0.584	1.00
289_V	338_G	0.583	1.00
15_R	200_G	0.582	1.00
78_R	317_W	0.578	1.00
7_P	160_L	0.576	1.00
371_I	411_V	0.574	1.00
178_W	201_A	0.573	1.00
355_F	384_P	0.571	1.00
211_L	216_A	0.571	1.00
245_L	265_C	0.571	1.00
78_R	81_P	0.570	1.00
256_E	259_R	0.570	1.00
254_L	257_Q	0.569	1.00
69_W	193_M	0.569	1.00
148_L	319_N	0.567	1.00
306_W	351_L	0.567	1.00
7_P	198_Y	0.566	1.00
354_L	361_G	0.564	1.00
188_S	244_L	0.564	1.00
97_N	151_A	0.563	1.00
181_S	223_L	0.562	1.00
349_G	364_P	0.562	1.00
379_Q	430_E	0.561	1.00
57_L	72_L	0.560	1.00
147_G	363_Q	0.560	1.00
180_L	203_M	0.560	1.00
22_R	25_D	0.559	1.00
370_V	415_L	0.559	1.00
54_G	100_L	0.558	1.00
376_A	410_W	0.558	1.00
109_E	113_P	0.557	1.00
368_E	396_A	0.555	1.00
177_D	180_L	0.554	1.00
15_R	174_D	0.553	1.00
139_M	153_V	0.553	1.00
113_P	117_S	0.552	1.00
113_P	119_H	0.552	1.00
420_Q	424_W	0.550	1.00
374_H	377_V	0.549	1.00
135_R	156_Y	0.548	1.00
385_V	397_V	0.547	1.00
164_Q	167_L	0.547	1.00
8_W	11_W	0.545	1.00
81_P	140_T	0.543	1.00
349_G	365_E	0.543	1.00
36_R	40_L	0.543	1.00
222_S	246_G	0.542	1.00
42_S	46_V	0.542	1.00
367_V	394_P	0.542	1.00
86_L	91_L	0.542	1.00
225_P	248_A	0.542	1.00
369_R	373_A	0.542	1.00
165_G	169_L	0.541	1.00
279_C	289_V	0.540	1.00
96_P	114_A	0.539	1.00
57_L	65_T	0.539	1.00
326_V	333_A	0.538	1.00
82_V	95_L	0.537	1.00
179_L	214_M	0.537	1.00
180_L	189_G	0.535	1.00
162_S	166_V	0.534	1.00
216_A	236_S	0.534	1.00
259_R	264_R	0.534	1.00
258_A	265_C	0.534	1.00
86_L	185_F	0.532	1.00
268_G	280_A	0.532	1.00
144_G	150_K	0.529	1.00
49_V	101_Q	0.529	1.00
246_G	268_G	0.528	1.00
245_L	267_C	0.526	1.00
353_N	364_P	0.526	1.00
180_L	205_V	0.526	1.00
98_L	151_A	0.526	1.00
6_W	130_T	0.524	1.00
98_L	139_M	0.523	1.00
163_A	195_R	0.523	1.00
307_L	312_M	0.522	1.00
246_G	277_T	0.522	1.00
58_R	105_V	0.522	1.00
152_A	272_T	0.520	1.00
30_W	197_L	0.520	1.00
8_W	37_V	0.520	1.00
282_E	291_S	0.520	1.00
255_T	267_C	0.519	1.00
162_S	278_V	0.519	1.00
188_S	268_G	0.519	1.00
219_T	239_S	0.519	1.00
369_R	372_A	0.518	1.00
371_I	382_I	0.517	1.00
357_S	392_H	0.517	1.00
300_I	303_N	0.516	1.00
313_A	332_Y	0.515	1.00
164_Q	168_S	0.515	1.00
367_V	421_P	0.515	1.00
21_L	33_L	0.513	1.00
146_T	150_K	0.513	1.00
335_R	352_D	0.512	1.00
232_L	254_L	0.511	1.00
315_G	320_G	0.510	1.00
60_W	208_K	0.509	1.00
165_G	293_L	0.509	1.00
143_S	149_P	0.507	1.00
143_S	150_K	0.506	1.00
37_V	70_L	0.505	1.00
172_F	195_R	0.504	1.00
90_L	366_E	0.504	1.00
77_A	102_F	0.503	1.00
245_L	258_A	0.503	1.00
35_A	38_D	0.503	1.00
47_Q	117_S	0.503	1.00
21_L	28_L	0.502	1.00
73_L	79_V	0.502	1.00
31_R	34_C	0.502	1.00
412_K	421_P	0.500	1.00
403_E	426_T	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3tsyA	2	0.7827	100	0.133	Contact Map
3g7sA	2	0.9091	100	0.139	Contact Map
1mdbA	1	1	100	0.14	Contact Map
3etcA	2	0.9579	100	0.146	Contact Map
1v25A	2	0.949	100	0.148	Contact Map
1pg4A	1	0.9978	100	0.149	Contact Map
3wvnA	1	0.7561	100	0.151	Contact Map
4lgcA	1	0.7583	100	0.152	Contact Map
2vsqA	1	0.9978	100	0.153	Contact Map
3ni2A	1	0.9889	100	0.155	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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