GREMLIN Database
PT1P - Phosphoenolpyruvate-protein phosphotransferase PtsP
UniProt: P37177 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG12188
Length: 748 (716)
Sequences: 438 (302)
Seq/√Len: 11.3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
539_V572_I6.8531.00
566_D611_R6.7531.00
179_G185_G5.1921.00
652_A656_R5.1371.00
617_V686_Y4.8891.00
204_D208_E4.7561.00
68_L99_I4.6821.00
345_G386_V4.2871.00
50_Y79_G4.0660.99
385_I405_Y3.9850.99
208_E215_A3.9220.99
673_G691_M3.8310.99
324_I345_G3.7920.99
369_V388_G3.6520.98
602_V650_A3.6330.98
553_N591_R3.4310.98
185_G189_A3.4280.98
324_I384_L3.3260.97
204_D211_R3.2800.97
682_I703_L3.0390.95
300_A306_L2.9580.94
596_L601_M2.8770.93
204_D207_L2.8760.93
300_A304_R2.8720.93
302_G305_L2.8600.93
66_V99_I2.8460.93
89_D92_K2.8370.93
74_I110_F2.7910.92
215_A220_A2.7440.92
617_V651_L2.6710.91
433_E687_R2.6260.90
572_I592_I2.6230.90
177_A185_G2.6130.90
654_I662_G2.5980.89
208_E211_R2.5950.89
151_A651_L2.5850.89
194_M197_V2.5700.89
182_I185_G2.5250.88
302_G306_L2.4510.86
89_D108_R2.4230.85
465_I619_T2.4180.85
212_L215_A2.4030.85
181_A184_E2.3990.85
300_A309_L2.3960.85
177_A189_A2.3940.85
461_Y466_P2.3940.85
43_A70_F2.3450.84
369_V393_L2.3030.82
560_T600_S2.3030.82
303_Q306_L2.2960.82
204_D215_A2.2550.81
626_I650_A2.2450.81
19_N23_N2.2290.80
187_Q190_T2.2080.80
266_S270_W2.1970.79
74_I90_A2.1680.78
30_C56_R2.1640.78
425_L566_D2.1620.78
208_E212_L2.1310.77
301_L306_L2.1230.77
651_L686_Y2.1070.76
619_T667_L2.1010.76
683_G715_A2.0930.76
178_P183_A2.0870.75
383_T402_L2.0530.74
133_R139_E2.0410.74
299_R302_G2.0330.73
324_I386_V2.0250.73
562_L604_M2.0100.73
659_E687_R2.0090.72
565_V612_V1.9860.72
404_E408_L1.9830.71
546_N550_G1.9820.71
112_G388_G1.9790.71
179_G184_E1.9780.71
181_A185_G1.9500.70
181_A187_Q1.9460.70
178_P182_I1.9410.70
446_E455_I1.9280.69
42_L619_T1.9220.69
405_Y502_V1.9180.69
480_V544_R1.9180.69
304_R309_L1.9130.69
556_L572_I1.9100.68
679_A706_I1.8940.68
425_L704_R1.8910.68
127_V143_L1.8770.67
522_W530_D1.8650.67
34_D65_T1.8590.66
211_R215_A1.8260.65
179_G182_I1.8180.64
301_L304_R1.8080.64
384_L393_L1.8080.64
85_I703_L1.7830.63
77_L95_S1.7680.62
301_L309_L1.7480.61
534_I649_R1.7440.61
385_I502_V1.7330.61
430_K707_D1.7250.60
427_A454_R1.7140.60
169_T393_L1.7100.60
183_A187_Q1.7020.59
330_L346_V1.6930.59
369_V386_V1.6920.59
197_V204_D1.6870.58
497_L542_M1.6860.58
251_D275_V1.6810.58
256_R395_V1.6800.58
322_R344_V1.6760.58
78_V85_I1.6680.58
306_L309_L1.6630.57
300_A308_H1.6610.57
182_I189_A1.6600.57
302_G307_F1.6600.57
334_T698_R1.6580.57
182_I187_Q1.6580.57
623_T673_G1.6530.57
50_Y68_L1.6420.56
66_V555_L1.6390.56
179_G187_Q1.6330.56
68_L98_Y1.6320.56
177_A187_Q1.6320.56
687_R712_E1.6300.56
183_A188_D1.6300.56
111_L127_V1.6280.56
209_R263_D1.6180.55
605_L654_I1.6140.55
382_R396_D1.6050.55
558_M598_V1.6010.54
520_L625_Y1.5990.54
433_E708_Y1.5890.54
525_I559_V1.5880.54
217_E554_I1.5850.54
194_M200_A1.5810.53
185_G190_T1.5670.53
37_V68_L1.5520.52
23_N60_K1.5490.52
502_V592_I1.5370.51
37_V98_Y1.5340.51
707_D710_E1.5320.51
79_G579_V1.5270.51
652_A719_L1.5240.51
244_L247_H1.5220.50
496_T555_L1.5150.50
299_R303_Q1.5130.50
678_V689_L1.5070.50
363_A673_G1.5030.50
615_I658_A1.5030.50
680_I684_L1.5020.50
278_K534_I1.4930.49
92_K716_Q1.4880.49
89_D672_A1.4790.48
62_R101_S1.4790.48
300_A307_F1.4780.48
596_L638_N1.4740.48
55_T62_R1.4650.48
112_G125_L1.4650.48
638_N699_A1.4610.48
318_A709_A1.4580.47
324_I662_G1.4540.47
303_Q307_F1.4510.47
482_Q509_P1.4470.47
25_L105_E1.4460.47
76_G110_F1.4330.46
369_V520_L1.4290.46
313_N364_L1.4250.46
299_R304_R1.4230.46
244_L686_Y1.4150.45
361_V455_I1.4120.45
267_V270_W1.4060.45
682_I708_Y1.4050.45
627_L644_H1.4000.45
388_G675_P1.3950.44
27_T56_R1.3950.44
301_L307_F1.3850.44
288_D442_G1.3850.44
167_R435_I1.3840.44
157_S640_Y1.3810.44
183_A186_W1.3800.44
75_V79_G1.3780.44
300_A303_Q1.3720.43
299_R309_L1.3700.43
299_R308_H1.3640.43
504_A519_C1.3640.43
41_Y74_I1.3530.42
652_A684_L1.3500.42
248_L524_G1.3480.42
197_V208_E1.3390.42
379_L512_P1.3380.42
75_V127_V1.3350.41
542_M552_L1.3290.41
273_K277_E1.3240.41
191_L194_M1.3220.41
241_I327_A1.3190.41
252_T569_R1.3190.41
80_R97_K1.3180.41
75_V126_V1.3120.40
24_I40_V1.3120.40
75_V109_A1.3090.40
177_A186_W1.3050.40
680_I718_S1.3040.40
40_V386_V1.3010.40
115_I362_R1.3000.40
37_V41_Y1.2980.40
530_D635_R1.2980.40
9_V21_A1.2960.40
200_A203_L1.2950.40
435_I682_I1.2920.39
539_V556_L1.2920.39
366_I395_V1.2890.39
205_P208_E1.2850.39
608_L646_A1.2830.39
216_L346_V1.2790.39
679_A711_A1.2780.39
137_E477_E1.2760.39
140_E556_L1.2760.39
388_G544_R1.2750.39
691_M703_L1.2700.38
456_D697_A1.2660.38
607_H649_R1.2610.38
619_T684_L1.2580.38
525_I568_A1.2530.38
208_E220_A1.2490.37
298_L458_I1.2480.37
179_G186_W1.2460.37
181_A186_W1.2450.37
458_I667_L1.2360.37
575_A578_E1.2350.37
302_G309_L1.2340.37
185_G188_D1.2310.37
324_I592_I1.2270.36
202_T208_E1.2260.36
494_P591_R1.2230.36
302_G308_H1.2230.36
300_A305_L1.2220.36
299_R306_L1.2210.36
276_I298_L1.2210.36
212_L216_L1.2190.36
220_A226_Y1.2170.36
37_V75_V1.2150.36
18_L78_V1.2100.36
129_Q692_N1.2090.36
326_V421_D1.1980.35
76_G112_G1.1950.35
5_L8_I1.1930.35
9_V12_V1.1870.35
338_L348_V1.1850.35
98_Y102_V1.1810.34
80_R95_S1.1790.34
288_D510_Y1.1770.34
290_Y633_N1.1760.34
262_V352_A1.1730.34
180_V183_A1.1730.34
468_M654_I1.1720.34
410_S710_E1.1700.34
107_F403_Q1.1690.34
62_R333_T1.1660.34
634_T667_L1.1660.34
206_A324_I1.1630.34
82_A683_G1.1580.33
458_I527_I1.1560.33
600_S713_N1.1560.33
209_R259_F1.1490.33
68_L102_V1.1410.33
425_L546_N1.1400.33
328_D350_D1.1360.32
626_I647_M1.1360.32
336_A404_E1.1340.32
204_D260_A1.1330.32
291_L509_P1.1290.32
86_N140_E1.1280.32
706_I711_A1.1230.32
178_P184_E1.1210.32
444_S606_P1.1170.32
362_R673_G1.1160.32
536_L575_A1.1090.31
182_I186_W1.1080.31
251_D701_Y1.1040.31
455_I555_L1.1040.31
360_M677_C1.1010.31
62_R429_L1.0980.31
303_Q605_L1.0980.31
284_A723_L1.0970.31
428_Q434_R1.0950.31
245_Y363_A1.0940.31
321_E365_G1.0920.31
332_A463_T1.0920.31
504_A511_M1.0860.30
78_V112_G1.0850.30
192_P198_Y1.0850.30
145_T442_G1.0810.30
42_L476_E1.0790.30
125_L388_G1.0790.30
295_A360_M1.0780.30
80_R559_V1.0770.30
601_M605_L1.0750.30
654_I665_L1.0750.30
476_E540_R1.0750.30
243_D534_I1.0750.30
29_I701_Y1.0740.30
625_Y645_P1.0740.30
612_V651_L1.0740.30
176_A182_I1.0740.30
159_L534_I1.0710.30
325_L626_I1.0710.30
256_R259_F1.0700.30
203_L369_V1.0660.30
567_E571_L1.0600.29
40_V346_V1.0590.29
398_E458_I1.0590.29
241_I441_A1.0570.29
249_L254_L1.0550.29
401_L559_V1.0500.29
37_V102_V1.0490.29
121_L584_G1.0490.29
62_R102_V1.0450.29
204_D212_L1.0430.29
623_T647_M1.0400.29
421_D615_I1.0360.28
67_T420_E1.0310.28
78_V463_T1.0280.28
390_R393_L1.0260.28
463_T673_G1.0260.28
393_L489_M1.0250.28
426_P559_V1.0230.28
442_G530_D1.0230.28
667_L673_G1.0220.28
105_E596_L1.0180.28
520_L532_P1.0160.28
637_A647_M1.0150.28
466_P640_Y1.0130.27
449_E683_G1.0120.27
290_Y530_D1.0100.27
177_A184_E1.0090.27
147_A641_D1.0090.27
55_T58_L1.0080.27
446_E601_M1.0080.27
247_H671_M1.0040.27
176_A187_Q1.0040.27
279_F298_L1.0040.27
402_L406_Q1.0030.27
345_G452_G1.0010.27
159_L642_S0.9990.27
171_I174_L0.9990.27
276_I302_G0.9970.27
245_Y352_A0.9960.27
36_E572_I0.9960.27
600_S643_L0.9960.27
220_A223_F0.9940.27
187_Q560_T0.9940.27
242_F249_L0.9930.27
297_D367_P0.9910.27
60_K592_I0.9870.26
15_A89_D0.9860.26
82_A255_R0.9800.26
324_I416_S0.9790.26
652_A716_Q0.9780.26
206_A428_Q0.9770.26
12_V696_V0.9770.26
211_R219_A0.9730.26
383_T535_F0.9730.26
170_R174_L0.9690.26
247_H444_S0.9680.26
446_E454_R0.9660.26
486_M572_I0.9620.26
386_V596_L0.9620.26
437_V696_V0.9620.26
673_G696_V0.9610.25
98_Y101_S0.9590.25
186_W189_A0.9580.25
60_K67_T0.9570.25
176_A181_A0.9550.25
109_A559_V0.9530.25
348_V536_L0.9510.25
109_A251_D0.9510.25
228_K321_E0.9500.25
193_L200_A0.9500.25
642_S671_M0.9490.25
59_K107_F0.9480.25
154_L600_S0.9470.25
598_V626_I0.9470.25
458_I559_V0.9450.25
435_I719_L0.9430.25
62_R705_R0.9410.25
242_F644_H0.9400.25
216_L600_S0.9400.25
467_F673_G0.9370.25
301_L308_H0.9370.25
254_L639_I0.9370.25
268_A442_G0.9360.25
194_M199_Q0.9350.25
71_D95_S0.9350.25
566_D708_Y0.9340.24
246_S249_L0.9320.24
304_R331_S0.9310.24
75_V699_A0.9300.24
8_I358_A0.9300.24
679_A702_L0.9300.24
596_L654_I0.9270.24
140_E542_M0.9270.24
342_R676_M0.9270.24
598_V604_M0.9260.24
55_T63_G0.9250.24
633_N636_V0.9240.24
520_L636_V0.9220.24
537_I695_S0.9220.24
476_E520_L0.9190.24
127_V381_R0.9180.24
199_Q273_K0.9170.24
336_A536_L0.9160.24
75_V113_V0.9130.24
180_V186_W0.9120.24
191_L208_E0.9080.24
193_L198_Y0.9080.24
422_D700_K0.9080.24
504_A579_V0.9060.23
283_F632_N0.9050.23
702_L706_I0.9030.23
336_A368_T0.9020.23
442_G522_W0.9010.23
389_Y412_E0.9010.23
80_R619_T0.9000.23
137_E646_A0.8980.23
326_V358_A0.8980.23
560_T576_G0.8950.23
293_E532_P0.8930.23
82_A617_V0.8910.23
490_F697_A0.8910.23
334_T354_N0.8880.23
51_Y64_R0.8860.23
37_V152_A0.8860.23
138_S259_F0.8850.23
358_A472_G0.8850.23
347_V405_Y0.8840.23
192_P195_E0.8820.23
429_L702_L0.8800.23
216_L251_D0.8790.23
662_G710_E0.8790.23
29_I602_V0.8790.23
326_V399_P0.8770.22
142_F150_M0.8750.22
91_Q386_V0.8740.22
50_Y99_I0.8690.22
13_A641_D0.8690.22
87_L673_G0.8670.22
176_A185_G0.8610.22
665_L672_A0.8610.22
671_M686_Y0.8600.22
598_V625_Y0.8550.22
214_G324_I0.8550.22
42_L352_A0.8530.22
145_T558_M0.8510.22
229_R719_L0.8490.22
36_E107_F0.8480.22
609_A658_A0.8480.22
554_I643_L0.8460.21
96_F394_L0.8460.21
656_R665_L0.8450.21
605_L615_I0.8420.21
508_L666_R0.8410.21
137_E212_L0.8400.21
11_K88_A0.8400.21
43_A102_V0.8400.21
337_E527_I0.8400.21
61_P132_L0.8390.21
479_Q558_M0.8390.21
61_P345_G0.8380.21
100_P591_R0.8370.21
295_A519_C0.8360.21
241_I492_D0.8360.21
85_I354_N0.8340.21
578_E592_I0.8300.21
234_A429_L0.8280.21
367_P474_P0.8270.21
359_I429_L0.8260.21
203_L211_R0.8250.21
129_Q133_R0.8230.21
395_V682_I0.8220.21
479_Q540_R0.8220.21
461_Y511_M0.8200.21
222_E308_H0.8180.21
438_M688_H0.8170.21
434_R456_D0.8170.21
458_I469_L0.8130.20
433_E712_E0.8130.20
347_V386_V0.8120.20
154_L305_L0.8120.20
441_A463_T0.8120.20
78_V110_F0.8110.20
179_G190_T0.8110.20
602_V619_T0.8090.20
275_V626_I0.8090.20
439_L566_D0.8080.20
366_I567_E0.8080.20
509_P692_N0.8070.20
355_S371_G0.8070.20
47_R79_G0.8060.20
393_L661_H0.8060.20
321_E509_P0.8050.20
427_A432_G0.8050.20
617_V692_N0.8050.20
222_E647_M0.8040.20
559_V711_A0.8040.20
596_L658_A0.8030.20
716_Q720_E0.8000.20
283_F286_L0.8000.20
430_K709_A0.7990.20
592_I666_R0.7990.20
27_T31_L0.7990.20
180_V527_I0.7960.20
469_L665_L0.7950.20
378_V492_D0.7950.20
148_T555_L0.7930.20
184_E187_Q0.7930.20
556_L568_A0.7930.20
197_V203_L0.7920.20
197_V211_R0.7910.20
248_L298_L0.7880.20
41_Y76_G0.7880.20
349_R601_M0.7880.20
176_A179_G0.7880.20
272_V348_V0.7860.20
37_V497_L0.7850.20
361_V564_E0.7850.20
524_G556_L0.7840.19
25_L37_V0.7830.19
129_Q603_F0.7790.19
148_T531_Q0.7790.19
370_M551_N0.7780.19
426_P588_P0.7760.19
176_A189_A0.7750.19
414_E566_D0.7740.19
328_D331_S0.7740.19
510_Y681_L0.7740.19
524_G674_D0.7730.19
334_T497_L0.7730.19
180_V184_E0.7720.19
234_A427_A0.7720.19
35_T682_I0.7710.19
567_E653_M0.7710.19
25_L40_V0.7710.19
55_T463_T0.7690.19
155_S275_V0.7690.19
554_I572_I0.7670.19
208_E268_A0.7670.19
461_Y473_F0.7660.19
148_T152_A0.7660.19
178_P181_A0.7650.19
487_L520_L0.7640.19
652_A703_L0.7640.19
39_S76_G0.7630.19
89_D358_A0.7630.19
37_V266_S0.7630.19
429_L504_A0.7630.19
577_R713_N0.7620.19
409_I413_I0.7610.19
427_A704_R0.7610.19
548_A617_V0.7610.19
312_A315_G0.7590.19
422_D703_L0.7580.19
394_L398_E0.7580.19
20_E68_L0.7570.19
331_S587_I0.7570.19
346_V663_I0.7560.19
181_A188_D0.7540.19
296_G707_D0.7520.19
177_A183_A0.7500.18
30_C555_L0.7500.18
180_V185_G0.7500.18
93_H145_T0.7490.18
288_D522_W0.7480.18
74_I638_N0.7480.18
131_E577_R0.7470.18
265_G395_V0.7460.18
322_R400_V0.7450.18
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319_W324_I0.6100.15
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204_D220_A0.5640.14
372_A650_A0.5640.14
454_R697_A0.5640.14
709_A720_E0.5640.14
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286_L544_R0.5630.14
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14_S24_I0.5520.13
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528_T551_N0.5520.13
35_T45_H0.5520.13
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97_K102_V0.5510.13
13_A332_A0.5510.13
384_L395_V0.5510.13
476_E629_V0.5500.13
569_R613_D0.5500.13
389_Y590_P0.5490.13
489_M559_V0.5490.13
251_D330_L0.5490.13
687_R703_L0.5490.13
75_V96_F0.5490.13
313_N316_P0.5480.13
450_K527_I0.5480.13
78_V357_A0.5470.13
177_A182_I0.5470.13
225_R709_A0.5470.13
348_V693_G0.5460.13
151_A671_M0.5460.13
290_Y442_G0.5450.13
244_L441_A0.5450.13
655_A659_E0.5450.13
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112_G370_M0.5440.13
52_L58_L0.5430.13
195_E198_Y0.5420.13
184_E189_A0.5420.13
365_G368_T0.5410.13
324_I407_R0.5410.13
556_L560_T0.5400.13
471_S703_L0.5390.13
77_L81_L0.5390.13
179_G243_D0.5390.13
473_F508_L0.5390.13
123_G128_Q0.5390.13
324_I721_A0.5380.13
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558_M604_M0.5370.13
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287_S298_L0.5330.13
57_G73_G0.5330.13
524_G590_P0.5330.13
219_A308_H0.5320.13
12_V617_V0.5320.13
53_M64_R0.5320.13
249_L625_Y0.5320.13
365_G479_Q0.5320.13
466_P698_R0.5310.13
24_I59_K0.5310.13
211_R441_A0.5310.13
30_C60_K0.5310.13
252_T468_M0.5300.13
283_F590_P0.5300.13
206_A215_A0.5300.13
25_L692_N0.5290.13
327_A710_E0.5290.13
333_T502_V0.5290.13
559_V696_V0.5290.13
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655_A684_L0.5280.13
358_A554_I0.5280.13
22_L94_P0.5280.13
35_T537_I0.5280.13
718_S721_A0.5270.13
131_E699_A0.5270.13
34_D384_L0.5260.13
190_T326_V0.5260.13
627_L645_P0.5260.13
68_L705_R0.5260.13
496_T661_H0.5250.13
40_V83_E0.5250.13
212_L258_L0.5250.13
520_L525_I0.5250.13
461_Y670_E0.5240.13
98_Y106_R0.5240.13
71_D346_V0.5240.13
127_V380_H0.5240.13
247_H251_D0.5240.13
254_L689_L0.5240.13
133_R357_A0.5230.13
416_S707_D0.5230.13
560_T565_V0.5220.13
251_D684_L0.5210.13
533_E609_A0.5210.13
40_V716_Q0.5190.13
384_L718_S0.5190.13
438_M667_L0.5180.13
579_V640_Y0.5180.13
7_E330_L0.5170.13
283_F627_L0.5170.13
86_N623_T0.5160.13
414_E706_I0.5160.13
373_D439_L0.5160.13
229_R662_G0.5160.13
401_L667_L0.5140.13
46_D111_L0.5140.13
16_P23_N0.5130.13
347_V711_A0.5130.13
386_V426_P0.5130.13
133_R141_S0.5130.13
102_V266_S0.5120.12
193_L196_Q0.5120.12
173_A365_G0.5120.12
632_N672_A0.5120.12
430_K458_I0.5120.12
327_A441_A0.5110.12
107_F136_D0.5110.12
294_R297_D0.5110.12
377_S643_L0.5100.12
574_R674_D0.5100.12
40_V436_K0.5100.12
223_F534_I0.5100.12
182_I188_D0.5100.12
301_L633_N0.5090.12
394_L699_A0.5090.12
431_S531_Q0.5080.12
304_R308_H0.5080.12
422_D496_T0.5080.12
31_L588_P0.5080.12
452_G493_K0.5070.12
226_Y702_L0.5070.12
605_L609_A0.5060.12
488_Q652_A0.5060.12
503_G506_K0.5060.12
503_G630_D0.5060.12
167_R170_R0.5050.12
83_E334_T0.5050.12
38_C151_A0.5040.12
37_V330_L0.5040.12
20_E216_L0.5030.12
20_E72_E0.5030.12
74_I95_S0.5030.12
551_N590_P0.5030.12
73_G104_E0.5020.12
282_Q327_A0.5020.12
329_E674_D0.5020.12
242_F254_L0.5000.12
297_D506_K0.5000.12
297_D630_D0.5000.12
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2hwgA 2 0.7513 100 0.486 Contact Map
2wqdA 2 0.75 100 0.487 Contact Map
1kblA 2 0.9064 100 0.578 Contact Map
1vbgA 2 0.9091 100 0.581 Contact Map
2x0sA 2 0.9144 100 0.585 Contact Map
2olsA 2 0.742 100 0.651 Contact Map
2xz9A 2 0.4225 100 0.704 Contact Map
1zymA 2 0.3195 100 0.809 Contact Map
4l9zA 5 0.3743 100 0.859 Contact Map
3qqwA 3 0.3864 100 0.86 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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