GREMLIN Database
OGRK - Prophage P2 OGR protein
UniProt: P37057 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG12425
Length: 72 (63)
Sequences: 127 (83)
Seq/√Len: 10.5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
3_H18_Y3.7080.98
40_I47_R3.2530.96
37_A48_Y2.9540.93
3_H28_H2.2630.79
3_H26_R2.1760.76
2_F42_Y2.1340.74
25_E40_I2.0540.71
36_S48_Y1.8610.63
6_L37_A1.8160.61
3_H17_R1.7960.60
8_Q31_Q1.7100.56
11_A26_R1.6660.54
13_A28_H1.5080.47
28_H41_T1.4990.47
45_V48_Y1.4000.42
3_H13_A1.3920.42
34_N55_V1.3460.40
8_Q17_R1.3150.38
1_M42_Y1.2880.37
37_A45_V1.2700.36
42_Y46_Q1.2660.36
13_A55_V1.2640.36
24_K29_Q1.1540.31
50_V53_G1.1190.30
36_S45_V1.0830.29
8_Q42_Y1.0640.28
3_H19_I1.0460.27
10_A31_Q1.0340.27
8_Q51_K1.0290.27
17_R41_T1.0130.26
2_F13_A1.0110.26
20_T23_T1.0090.26
33_V59_R0.9920.25
40_I48_Y0.9820.25
41_T48_Y0.9810.25
32_N38_T0.9590.24
19_I46_Q0.9350.23
14_R38_T0.9220.23
15_T50_V0.9200.23
53_G56_H0.9030.22
2_F45_V0.8860.22
13_A44_S0.8850.22
31_Q40_I0.8760.21
2_F46_Q0.8700.21
6_L45_V0.8500.21
25_E31_Q0.8490.20
15_T24_K0.8320.20
23_T34_N0.7970.19
37_A50_V0.7810.18
2_F41_T0.7740.18
49_I53_G0.7450.17
55_V58_V0.7410.17
9_H31_Q0.7330.17
57_V61_H0.7240.17
49_I57_V0.7210.17
6_L23_T0.7050.16
23_T31_Q0.6920.16
53_G57_V0.6710.16
21_D33_V0.6710.16
25_E47_R0.6490.15
6_L53_G0.6450.15
16_S24_K0.6440.15
18_Y29_Q0.6380.15
15_T46_Q0.6260.14
34_N61_H0.6250.14
14_R61_H0.6160.14
6_L50_V0.6130.14
8_Q13_A0.6090.14
25_E41_T0.6090.14
26_R58_V0.6060.14
44_S61_H0.5970.14
26_R30_C0.5960.14
18_Y28_H0.5960.14
47_R50_V0.5900.14
3_H11_A0.5870.14
44_S57_V0.5800.13
15_T26_R0.5710.13
56_H59_R0.5690.13
57_V60_P0.5610.13
33_V44_S0.5610.13
48_Y63_L0.5590.13
5_P12_H0.5550.13
58_V61_H0.5550.13
2_F15_T0.5530.13
12_H32_N0.5370.13
54_E57_V0.5370.13
53_G58_V0.5250.12
44_S59_R0.5230.12
36_S47_R0.5220.12
34_N53_G0.5170.12
22_T50_V0.5140.12
1_M27_Y0.5120.12
32_N43_E0.5050.12
26_R31_Q0.5000.12
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3ga8A 1 0.7639 87 0.867 Contact Map
4kisA 2 0.9861 78.8 0.879 Contact Map
1pqvS 1 0.5139 75.9 0.882 Contact Map
4cgyA 1 0 75.5 0.882 Contact Map
4e2xA 1 0.9722 75.3 0.882 Contact Map
3po3S 1 0.5139 72.2 0.885 Contact Map
2hu9A 1 0.9028 66.7 0.89 Contact Map
1tfiA 1 0.5139 66.5 0.89 Contact Map
1qypA 1 0.5139 65.6 0.891 Contact Map
1wjpA 1 0.875 59.3 0.895 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0045 seconds.