HRPB - ECOLI - GREMLIN Contacts

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HRPB - ATP-dependent RNA helicase HrpB

UniProt:	P37024	Sequences: MSSLPVAAVLPELLTALDCAPQVLLSAPTGAGKSTWLPLQLLAHPGINGKIILLEPRRLAARNVAQRLAELLNEKPGDTVGYRMRAQNCVGPNTRLEVVTEGVLTRMIQRDPELSGVGLVILDEFHERSLQADLALALLLDVQQGLRDDLKLLIMSATLDNDRLQQMLPEAPVVISEGRSFPVERRYLPLPAHQRFDDAVAVATAEMLRQESGSLLLFLPGVGEIQRVQEQLASRIGSDVLLCPLYGALSLNDQRKAILPAPQGMRKVVLATNIAETSLTIEGIRLVVDCAQERVARFDPRTGLTRLITQRVSQASMTQRAGRAGRLEPGISLHLIAKEQAERAAAQSEPEILQSDLSGLLMELLQWGCSDPAQMSWLDQPPVVNLLAAKRLLQMLGALEGERLSAQGQKMAALGNDPRLAAMLVSAKNDDEAATAAKIAAILEEPPRMGNSDLGVAFSRNQPAWQQRSQQLLKRLNVRGGEADSSLIAPLLAGAFADRIARRRGQDGRYQLANGMGAMLDANDALSRHEWLIAPLLLQGSASPDARILLALLVDIDELVQRCPQLVQQSDTVEWDDAQGTLKAWRRLQIGQLTVKVQPLAKPSEDELHQAMLNGIRDKGLSVLNWTAEAEQLRLRLLCAAKWLPEYDWPAVDDESLLAALETWLLPHMTGVHSLRGLKSLDIYQALRGLLDWGMQQRLDSELPAHYTVPTGSRIAIRYHEDNPPALAVRMQEMFGEATNPTIAQGRVPLVLELLSPAQRPLQITRDLSDFWKGAYREVQKEMKGRYPKHVWPDDPANTAPTRRTKKYS	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG12329
Length:	809 (714)
Sequences:	2745 (1778)
Seq/√Len:	66.5

ECOLI - HRPB HRPA

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
185_R	321_A	4.360	1.00
7_A	36_W	3.899	1.00
78_D	93_N	3.811	1.00
241_L	265_M	3.636	1.00
120_V	139_L	3.605	1.00
398_A	411_M	3.583	1.00
411_M	421_A	3.526	1.00
426_S	429_N	3.339	1.00
34_S	64_V	3.329	1.00
407_Q	422_A	3.251	1.00
75_K	78_D	3.232	1.00
321_A	332_S	3.200	1.00
74_E	79_T	3.175	1.00
580_G	672_V	3.149	1.00
314_Q	346_A	3.123	1.00
534_A	551_A	3.098	1.00
285_R	328_E	3.088	1.00
604_S	607_E	3.032	1.00
706_H	714_R	2.954	1.00
653_D	656_S	2.901	1.00
692_D	695_M	2.833	1.00
586_R	598_Q	2.804	1.00
501_A	518_A	2.800	1.00
52_I	99_V	2.799	1.00
585_W	597_V	2.797	1.00
200_V	217_L	2.687	1.00
219_L	270_L	2.630	1.00
9_V	174_V	2.601	1.00
25_L	37_L	2.596	1.00
655_E	659_A	2.587	1.00
502_R	531_W	2.573	1.00
199_A	203_A	2.546	1.00
66_Q	255_R	2.529	1.00
366_Q	404_L	2.516	1.00
709_V	715_I	2.500	1.00
556_I	560_V	2.495	1.00
79_T	95_R	2.486	1.00
631_E	634_R	2.468	1.00
49_G	118_G	2.455	1.00
371_D	374_Q	2.455	1.00
229_Q	270_L	2.453	1.00
186_R	331_I	2.428	1.00
14_L	40_Q	2.420	1.00
709_V	713_S	2.378	1.00
13_L	23_V	2.352	1.00
200_V	204_T	2.339	1.00
504_R	517_G	2.306	1.00
560_V	588_L	2.252	1.00
410_K	428_K	2.239	1.00
510_Y	520_L	2.221	1.00
163_R	379_D	2.209	1.00
21_P	143_Q	2.203	1.00
47_I	118_G	2.197	1.00
205_A	235_R	2.195	1.00
312_V	317_M	2.190	1.00
83_R	88_N	2.188	1.00
83_R	107_M	2.174	1.00
297_R	310_Q	2.171	1.00
183_V	325_G	2.153	1.00
67_R	71_L	2.144	1.00
637_L	652_V	2.122	1.00
634_R	654_D	2.087	1.00
68_L	98_V	2.080	1.00
651_A	656_S	2.065	1.00
569_Q	586_R	2.053	1.00
194_Q	202_V	2.044	1.00
14_L	44_H	2.038	1.00
634_R	638_L	2.022	1.00
682_D	685_Q	2.020	1.00
26_S	161_N	2.010	1.00
318_T	321_A	2.001	1.00
365_L	399_L	2.001	1.00
49_G	116_G	1.994	1.00
217_L	288_V	1.993	1.00
587_R	594_T	1.991	1.00
200_V	228_V	1.990	1.00
420_L	440_A	1.981	1.00
273_N	312_V	1.951	1.00
206_E	210_Q	1.946	1.00
518_A	548_I	1.943	1.00
24_L	164_L	1.938	1.00
617_R	662_E	1.935	1.00
214_S	261_A	1.927	1.00
46_G	119_L	1.907	1.00
615_G	619_K	1.901	1.00
188_L	206_E	1.886	1.00
296_A	305_T	1.876	1.00
571_D	586_R	1.872	1.00
9_V	12_E	1.871	1.00
708_T	714_R	1.851	1.00
221_G	224_E	1.842	1.00
576_D	583_K	1.817	1.00
707_Y	717_I	1.816	1.00
372_P	386_L	1.813	1.00
394_Q	400_E	1.806	1.00
15_T	19_C	1.806	1.00
660_A	663_T	1.805	1.00
166_Q	170_E	1.801	1.00
229_Q	233_A	1.800	1.00
479_R	482_E	1.799	1.00
698_R	701_S	1.799	1.00
12_E	15_T	1.790	1.00
475_R	479_R	1.784	1.00
207_M	333_L	1.782	1.00
208_L	268_V	1.773	1.00
611_A	615_G	1.769	1.00
336_I	341_A	1.767	1.00
36_W	71_L	1.746	1.00
26_S	175_I	1.745	1.00
492_L	533_I	1.743	1.00
6_V	36_W	1.736	1.00
681_L	686_A	1.731	1.00
267_K	281_I	1.727	1.00
520_L	551_A	1.726	1.00
232_L	242_L	1.722	1.00
472_L	475_R	1.718	1.00
295_V	349_E	1.708	0.99
215_L	268_V	1.707	0.99
630_A	633_L	1.704	0.99
318_T	341_A	1.696	0.99
476_L	479_R	1.690	0.99
338_K	342_E	1.689	0.99
471_Q	474_K	1.688	0.99
361_L	386_L	1.673	0.99
457_A	461_N	1.671	0.99
198_D	231_Q	1.656	0.99
503_R	530_E	1.652	0.99
456_V	460_R	1.651	0.99
46_G	118_G	1.651	0.99
22_Q	143_Q	1.643	0.99
204_T	217_L	1.635	0.99
125_F	154_I	1.625	0.99
50_K	97_E	1.615	0.99
203_A	207_M	1.614	0.99
82_Y	87_Q	1.593	0.99
501_A	532_L	1.589	0.99
640_A	703_L	1.587	0.99
250_S	253_D	1.583	0.99
472_L	479_R	1.583	0.99
475_R	482_E	1.581	0.99
273_N	293_E	1.567	0.99
220_P	292_Q	1.565	0.99
267_K	282_E	1.564	0.99
426_S	430_D	1.563	0.99
317_M	336_I	1.559	0.99
341_A	344_A	1.559	0.99
462_Q	465_W	1.559	0.99
67_R	70_E	1.556	0.99
426_S	494_G	1.545	0.99
471_Q	475_R	1.543	0.99
251_L	255_R	1.541	0.99
489_A	552_L	1.540	0.99
222_V	246_Y	1.532	0.99
548_I	551_A	1.527	0.99
244_P	249_L	1.523	0.99
510_Y	527_S	1.519	0.99
204_T	268_V	1.518	0.99
567_V	588_L	1.515	0.99
311_R	344_A	1.515	0.99
258_I	282_E	1.515	0.99
129_S	132_A	1.515	0.99
453_D	458_F	1.498	0.99
109_Q	363_E	1.498	0.99
475_R	478_V	1.497	0.99
502_R	530_E	1.496	0.99
69_A	77_G	1.494	0.99
639_C	643_W	1.485	0.99
400_E	403_R	1.485	0.99
39_L	72_L	1.479	0.99
80_V	96_L	1.470	0.98
360_L	377_W	1.470	0.98
509_R	545_D	1.455	0.98
684_Y	688_R	1.452	0.98
686_A	690_L	1.445	0.98
199_A	202_V	1.441	0.98
422_A	426_S	1.439	0.98
10_L	40_Q	1.433	0.98
674_S	677_G	1.432	0.98
473_L	476_L	1.429	0.98
555_D	558_E	1.428	0.98
386_L	390_K	1.420	0.98
83_R	97_E	1.416	0.98
113_E	146_L	1.414	0.98
25_L	153_L	1.410	0.98
567_V	595_V	1.400	0.98
16_A	174_V	1.399	0.98
232_L	270_L	1.396	0.98
24_L	165_Q	1.394	0.98
203_A	206_E	1.391	0.98
165_Q	169_P	1.389	0.98
461_N	465_W	1.388	0.98
419_R	498_D	1.385	0.98
140_L	168_L	1.380	0.98
457_A	460_R	1.376	0.98
569_Q	588_L	1.367	0.98
673_H	677_G	1.362	0.97
162_D	166_Q	1.357	0.97
559_L	567_V	1.355	0.97
468_R	471_Q	1.350	0.97
202_V	206_E	1.346	0.97
424_L	440_A	1.341	0.97
617_R	661_L	1.336	0.97
538_L	549_L	1.334	0.97
698_R	702_E	1.332	0.97
204_T	207_M	1.325	0.97
10_L	43_A	1.325	0.97
253_D	256_K	1.323	0.97
200_V	206_E	1.318	0.97
88_N	107_M	1.317	0.97
122_L	139_L	1.316	0.97
229_Q	244_P	1.315	0.97
534_A	548_I	1.313	0.97
454_L	457_A	1.308	0.97
186_R	210_Q	1.306	0.97
498_D	513_A	1.300	0.97
194_Q	197_D	1.298	0.97
90_V	97_E	1.295	0.97
574_E	585_W	1.294	0.97
512_L	518_A	1.293	0.97
531_W	593_L	1.291	0.96
261_A	265_M	1.290	0.96
237_G	240_V	1.289	0.96
213_G	266_R	1.286	0.96
223_G	227_R	1.283	0.96
53_L	98_V	1.277	0.96
18_D	44_H	1.276	0.96
633_L	688_R	1.275	0.96
658_L	662_E	1.275	0.96
16_A	23_V	1.273	0.96
668_H	689_G	1.269	0.96
261_A	264_G	1.268	0.96
215_L	286_L	1.268	0.96
143_Q	152_L	1.268	0.96
285_R	327_L	1.267	0.96
28_P	177_E	1.258	0.96
68_L	96_L	1.256	0.96
634_R	637_L	1.256	0.96
423_M	427_A	1.251	0.96
609_H	613_L	1.250	0.96
243_C	256_K	1.249	0.96
537_L	546_A	1.247	0.96
383_V	387_L	1.245	0.96
460_R	463_P	1.239	0.96
621_L	658_L	1.235	0.95
633_L	637_L	1.234	0.95
482_E	486_S	1.232	0.95
510_Y	529_H	1.231	0.95
603_P	608_L	1.230	0.95
72_L	80_V	1.229	0.95
198_D	201_A	1.227	0.95
125_F	164_L	1.227	0.95
371_D	390_K	1.224	0.95
490_P	561_Q	1.223	0.95
472_L	476_L	1.221	0.95
587_R	597_V	1.221	0.95
208_L	240_V	1.217	0.95
129_S	277_T	1.214	0.95
609_H	666_L	1.211	0.95
436_A	488_I	1.207	0.95
509_R	517_G	1.204	0.95
479_R	486_S	1.203	0.95
241_L	261_A	1.199	0.95
570_S	589_Q	1.195	0.95
199_A	206_E	1.195	0.95
291_A	336_I	1.193	0.95
478_V	482_E	1.187	0.94
282_E	327_L	1.177	0.94
14_L	18_D	1.175	0.94
241_L	267_K	1.175	0.94
200_V	203_A	1.173	0.94
201_A	231_Q	1.173	0.94
211_E	285_R	1.170	0.94
463_P	466_Q	1.169	0.94
469_S	473_L	1.167	0.94
201_A	204_T	1.162	0.94
17_L	23_V	1.161	0.94
211_E	331_I	1.160	0.94
83_R	103_V	1.156	0.94
468_R	472_L	1.149	0.93
50_K	116_G	1.148	0.93
186_R	211_E	1.148	0.93
430_D	491_L	1.145	0.93
284_I	327_L	1.143	0.93
139_L	152_L	1.138	0.93
671_G	674_S	1.134	0.93
373_A	383_V	1.133	0.93
52_I	120_V	1.132	0.93
490_P	562_R	1.131	0.93
3_S	7_A	1.124	0.93
211_E	286_L	1.123	0.93
197_D	227_R	1.122	0.93
201_A	205_A	1.118	0.92
107_M	117_V	1.110	0.92
572_T	587_R	1.104	0.92
657_L	664_W	1.101	0.92
478_V	483_A	1.101	0.92
167_M	376_S	1.097	0.92
293_E	312_V	1.096	0.92
241_L	256_K	1.096	0.92
721_E	724_P	1.096	0.92
144_Q	148_D	1.095	0.92
364_L	377_W	1.092	0.91
390_K	399_L	1.092	0.91
637_L	641_A	1.091	0.91
502_R	593_L	1.091	0.91
11_P	15_T	1.089	0.91
477_N	480_G	1.089	0.91
439_I	488_I	1.084	0.91
315_A	347_Q	1.083	0.91
470_Q	473_L	1.081	0.91
195_R	206_E	1.078	0.91
652_V	690_L	1.077	0.91
214_S	283_G	1.076	0.91
365_L	390_K	1.073	0.91
214_S	328_E	1.070	0.91
215_L	288_V	1.070	0.91
637_L	651_A	1.068	0.91
692_D	696_Q	1.067	0.91
639_C	703_L	1.065	0.90
74_E	78_D	1.063	0.90
473_L	478_V	1.061	0.90
111_D	115_S	1.056	0.90
161_N	173_V	1.053	0.90
228_V	290_C	1.052	0.90
513_A	593_L	1.050	0.90
458_F	462_Q	1.048	0.90
101_E	129_S	1.047	0.90
353_L	379_D	1.047	0.90
462_Q	472_L	1.046	0.90
105_T	131_Q	1.046	0.90
503_R	510_Y	1.045	0.90
688_R	696_Q	1.045	0.90
382_P	385_N	1.044	0.90
351_E	355_S	1.043	0.89
305_T	355_S	1.042	0.89
477_N	482_E	1.042	0.89
472_L	477_N	1.039	0.89
471_Q	478_V	1.038	0.89
482_E	485_S	1.033	0.89
257_A	267_K	1.033	0.89
184_E	331_I	1.033	0.89
162_D	173_V	1.032	0.89
214_S	243_C	1.031	0.89
226_Q	229_Q	1.030	0.89
717_I	725_P	1.028	0.89
101_E	105_T	1.023	0.89
165_Q	173_V	1.021	0.88
462_Q	466_Q	1.021	0.88
183_V	332_S	1.020	0.88
612_M	616_I	1.020	0.88
246_Y	249_L	1.019	0.88
160_D	347_Q	1.019	0.88
203_A	333_L	1.018	0.88
500_I	559_L	1.018	0.88
500_I	590_I	1.017	0.88
419_R	499_R	1.015	0.88
628_A	631_E	1.013	0.88
519_M	545_D	1.012	0.88
219_L	290_C	1.012	0.88
84_M	251_L	1.012	0.88
204_T	232_L	1.010	0.88
469_S	472_L	1.009	0.88
23_V	153_L	1.006	0.88
9_V	16_A	1.006	0.88
313_S	348_S	1.005	0.88
645_P	648_D	1.004	0.88
72_L	79_T	1.003	0.88
286_L	333_L	1.003	0.88
199_A	204_T	1.003	0.88
203_A	217_L	1.002	0.88
571_D	607_E	1.000	0.87
476_L	480_G	0.997	0.87
201_A	206_E	0.995	0.87
610_Q	614_N	0.993	0.87
531_W	556_I	0.989	0.87
529_H	553_L	0.987	0.87
52_I	97_E	0.987	0.87
134_L	364_L	0.984	0.87
211_E	328_E	0.982	0.86
358_S	392_L	0.976	0.86
204_T	208_L	0.975	0.86
536_L	549_L	0.975	0.86
53_L	121_I	0.974	0.86
97_E	107_M	0.974	0.86
432_E	491_L	0.972	0.86
474_K	477_N	0.972	0.86
414_L	421_A	0.971	0.86
64_V	277_T	0.970	0.86
113_E	142_V	0.967	0.86
207_M	331_I	0.965	0.85
612_M	675_L	0.964	0.85
185_R	318_T	0.960	0.85
576_D	599_P	0.959	0.85
314_Q	318_T	0.959	0.85
202_V	207_M	0.959	0.85
476_L	483_A	0.958	0.85
196_F	200_V	0.956	0.85
705_A	716_A	0.955	0.85
555_D	559_L	0.955	0.85
622_S	627_T	0.953	0.85
134_L	138_L	0.948	0.84
585_W	599_P	0.948	0.84
709_V	712_G	0.948	0.84
297_R	308_I	0.947	0.84
468_R	475_R	0.940	0.84
706_H	716_A	0.939	0.84
656_S	660_A	0.939	0.84
582_L	608_L	0.939	0.84
48_N	118_G	0.937	0.84
502_R	594_T	0.933	0.84
42_L	79_T	0.932	0.83
511_Q	593_L	0.930	0.83
606_D	610_Q	0.928	0.83
214_S	267_K	0.926	0.83
217_L	268_V	0.925	0.83
83_R	116_G	0.924	0.83
286_L	331_I	0.924	0.83
142_V	148_D	0.922	0.83
588_L	596_K	0.921	0.83
423_M	495_A	0.921	0.83
77_G	81_G	0.919	0.83
292_Q	382_P	0.919	0.83
492_L	535_P	0.919	0.83
268_V	288_V	0.918	0.83
197_D	228_V	0.916	0.82
36_W	67_R	0.913	0.82
91_G	94_T	0.912	0.82
240_V	268_V	0.911	0.82
154_I	168_L	0.909	0.82
229_Q	242_L	0.909	0.82
471_Q	479_R	0.907	0.82
273_N	316_S	0.904	0.82
185_R	334_H	0.904	0.82
474_K	478_V	0.904	0.82
274_I	548_I	0.902	0.81
665_L	669_M	0.898	0.81
31_A	176_S	0.898	0.81
637_L	649_W	0.897	0.81
162_D	175_I	0.897	0.81
500_I	554_V	0.893	0.81
54_L	101_E	0.893	0.81
84_M	87_Q	0.891	0.81
189_P	337_A	0.891	0.81
392_L	419_R	0.889	0.80
140_L	376_S	0.889	0.80
10_L	14_L	0.889	0.80
366_Q	412_A	0.889	0.80
392_L	498_D	0.888	0.80
154_I	164_L	0.886	0.80
423_M	440_A	0.884	0.80
641_A	649_W	0.884	0.80
41_L	119_L	0.884	0.80
195_R	198_D	0.883	0.80
59_L	251_L	0.882	0.80
296_A	308_I	0.882	0.80
687_L	690_L	0.882	0.80
406_A	409_Q	0.878	0.80
201_A	207_M	0.878	0.80
8_A	12_E	0.876	0.79
394_Q	399_L	0.876	0.79
554_V	559_L	0.876	0.79
636_R	688_R	0.874	0.79
467_Q	477_N	0.871	0.79
472_L	478_V	0.871	0.79
50_K	107_M	0.869	0.79
479_R	485_S	0.868	0.79
9_V	13_L	0.866	0.79
62_R	255_R	0.866	0.79
501_A	512_L	0.865	0.79
15_T	20_A	0.864	0.79
483_A	487_L	0.864	0.79
44_H	96_L	0.862	0.78
138_L	377_W	0.862	0.78
13_L	176_S	0.862	0.78
336_I	344_A	0.862	0.78
239_D	265_M	0.861	0.78
456_V	459_S	0.859	0.78
190_L	196_F	0.859	0.78
634_R	651_A	0.855	0.78
627_T	630_A	0.854	0.78
559_L	563_C	0.853	0.78
207_M	210_Q	0.853	0.78
188_L	203_A	0.851	0.77
629_E	632_Q	0.851	0.77
198_D	206_E	0.851	0.77
428_K	433_A	0.850	0.77
564_P	567_V	0.850	0.77
34_S	546_A	0.849	0.77
186_R	333_L	0.847	0.77
469_S	477_N	0.844	0.77
450_G	459_S	0.844	0.77
361_L	364_L	0.843	0.77
469_S	478_V	0.840	0.77
261_A	267_K	0.840	0.77
34_S	37_L	0.840	0.77
706_H	709_V	0.837	0.76
370_S	403_R	0.836	0.76
304_L	546_A	0.835	0.76
198_D	202_V	0.835	0.76
36_W	40_Q	0.835	0.76
207_M	286_L	0.835	0.76
359_G	417_D	0.834	0.76
430_D	490_P	0.833	0.76
479_R	483_A	0.832	0.76
421_A	424_L	0.831	0.76
617_R	659_A	0.829	0.76
273_N	296_A	0.828	0.76
660_A	690_L	0.828	0.76
39_L	68_L	0.828	0.76
494_G	562_R	0.827	0.75
504_R	511_Q	0.826	0.75
140_L	143_Q	0.826	0.75
644_L	649_W	0.824	0.75
314_Q	341_A	0.824	0.75
187_Y	341_A	0.823	0.75
165_Q	171_A	0.822	0.75
579_Q	583_K	0.821	0.75
672_V	677_G	0.821	0.75
511_Q	592_Q	0.821	0.75
612_M	672_V	0.821	0.75
650_P	692_D	0.821	0.75
646_E	649_W	0.817	0.75
140_L	167_M	0.817	0.75
269_V	284_I	0.817	0.75
349_E	353_L	0.816	0.74
469_S	474_K	0.815	0.74
108_I	135_A	0.815	0.74
502_R	511_Q	0.815	0.74
188_L	333_L	0.814	0.74
640_A	702_E	0.814	0.74
638_L	642_K	0.811	0.74
196_F	199_A	0.811	0.74
119_L	153_L	0.811	0.74
252_N	256_K	0.810	0.74
521_D	547_R	0.809	0.74
273_N	354_Q	0.809	0.74
68_L	71_L	0.808	0.74
295_V	310_Q	0.808	0.74
195_R	199_A	0.806	0.74
622_S	631_E	0.804	0.73
144_Q	376_S	0.802	0.73
641_A	648_D	0.801	0.73
313_S	316_S	0.800	0.73
228_V	231_Q	0.800	0.73
708_T	712_G	0.800	0.73
212_S	328_E	0.799	0.73
83_R	90_V	0.799	0.73
629_E	684_Y	0.798	0.73
683_I	686_A	0.797	0.73
705_A	714_R	0.797	0.73
13_L	25_L	0.795	0.73
327_L	531_W	0.792	0.72
481_G	485_S	0.790	0.72
249_L	253_D	0.789	0.72
478_V	485_S	0.787	0.72
670_T	674_S	0.786	0.72
200_V	207_M	0.784	0.71
11_P	14_L	0.784	0.71
518_A	534_A	0.782	0.71
478_V	481_G	0.782	0.71
34_S	444_E	0.781	0.71
312_V	344_A	0.780	0.71
613_L	617_R	0.778	0.71
437_A	441_A	0.778	0.71
63_N	258_I	0.777	0.71
205_A	234_S	0.777	0.71
619_K	623_V	0.776	0.71
54_L	125_F	0.774	0.70
631_E	635_L	0.774	0.70
191_P	194_Q	0.771	0.70
86_A	214_S	0.770	0.70
358_S	417_D	0.770	0.70
50_K	90_V	0.768	0.70
498_D	533_I	0.768	0.70
21_P	151_K	0.767	0.70
496_F	499_R	0.765	0.70
491_L	494_G	0.765	0.70
220_P	367_W	0.763	0.69
137_A	375_M	0.763	0.69
649_W	652_V	0.762	0.69
392_L	396_L	0.761	0.69
626_W	654_D	0.761	0.69
140_L	169_P	0.760	0.69
59_L	98_V	0.759	0.69
23_V	174_V	0.758	0.69
219_L	228_V	0.756	0.69
77_G	91_G	0.756	0.69
512_L	537_L	0.754	0.68
199_A	207_M	0.754	0.68
520_L	548_I	0.754	0.68
380_Q	694_G	0.750	0.68
261_A	269_V	0.750	0.68
14_L	43_A	0.750	0.68
121_I	153_L	0.746	0.68
105_T	363_E	0.746	0.68
66_Q	76_P	0.745	0.68
519_M	547_R	0.744	0.67
386_L	399_L	0.743	0.67
6_V	23_V	0.743	0.67
76_P	89_C	0.740	0.67
101_E	131_Q	0.740	0.67
688_R	700_D	0.740	0.67
531_W	559_L	0.740	0.67
641_A	646_E	0.738	0.67
225_I	270_L	0.737	0.67
6_V	13_L	0.737	0.67
635_L	639_C	0.735	0.66
352_I	381_P	0.735	0.66
410_K	413_A	0.733	0.66
185_R	332_S	0.733	0.66
512_L	534_A	0.732	0.66
642_K	648_D	0.730	0.66
106_R	363_E	0.730	0.66
624_L	676_R	0.728	0.66
28_P	176_S	0.728	0.66
76_P	274_I	0.727	0.66
244_P	257_A	0.726	0.66
37_L	64_V	0.722	0.65
470_Q	474_K	0.722	0.65
22_Q	140_L	0.720	0.65
108_I	368_G	0.720	0.65
293_E	348_S	0.720	0.65
493_A	533_I	0.719	0.65
340_Q	344_A	0.719	0.65
122_L	135_A	0.719	0.65
465_W	472_L	0.719	0.65
427_A	633_L	0.718	0.65
52_I	103_V	0.716	0.64
460_R	466_Q	0.715	0.64
51_I	96_L	0.714	0.64
679_K	707_Y	0.713	0.64
192_A	197_D	0.713	0.64
25_L	41_L	0.711	0.64
582_L	615_G	0.711	0.64
240_V	266_R	0.710	0.64
338_K	341_A	0.710	0.64
224_E	294_R	0.708	0.64
527_S	547_R	0.707	0.63
141_D	374_Q	0.706	0.63
626_W	634_R	0.706	0.63
39_L	55_E	0.705	0.63
41_L	46_G	0.704	0.63
293_E	310_Q	0.704	0.63
503_R	528_R	0.704	0.63
130_L	357_L	0.702	0.63
31_A	178_G	0.702	0.63
469_S	476_L	0.700	0.63
208_L	266_R	0.700	0.63
461_N	464_A	0.699	0.63
467_Q	476_L	0.698	0.62
169_P	172_P	0.697	0.62
258_I	281_I	0.696	0.62
577_D	619_K	0.695	0.62
277_T	316_S	0.695	0.62
664_W	667_P	0.693	0.62
694_G	701_S	0.692	0.62
207_M	213_G	0.692	0.62
9_V	176_S	0.691	0.62
270_L	415_G	0.691	0.62
407_Q	426_S	0.691	0.62
500_I	561_Q	0.689	0.61
481_G	486_S	0.689	0.61
458_F	461_N	0.689	0.61
107_M	110_R	0.688	0.61
51_I	153_L	0.688	0.61
397_G	400_E	0.687	0.61
67_R	98_V	0.686	0.61
556_I	593_L	0.685	0.61
42_L	51_I	0.685	0.61
84_M	399_L	0.684	0.61
571_D	600_L	0.684	0.61
394_Q	401_G	0.684	0.61
470_Q	479_R	0.682	0.61
258_I	267_K	0.682	0.61
535_P	552_L	0.680	0.60
642_K	722_D	0.679	0.60
476_L	482_E	0.679	0.60
630_A	684_Y	0.678	0.60
17_L	153_L	0.677	0.60
634_R	690_L	0.677	0.60
99_V	103_V	0.676	0.60
605_E	608_L	0.675	0.60
149_D	363_E	0.675	0.60
242_L	520_L	0.675	0.60
465_W	468_R	0.672	0.60
446_P	449_M	0.671	0.59
236_I	242_L	0.670	0.59
17_L	41_L	0.670	0.59
288_V	557_D	0.669	0.59
13_L	174_V	0.668	0.59
370_S	374_Q	0.668	0.59
211_E	214_S	0.667	0.59
632_Q	705_A	0.667	0.59
467_Q	471_Q	0.666	0.59
469_S	553_L	0.666	0.59
676_R	680_S	0.666	0.59
627_T	633_L	0.665	0.59
607_E	610_Q	0.664	0.59
31_A	179_R	0.664	0.59
672_V	681_L	0.663	0.59
677_G	681_L	0.663	0.59
505_G	510_Y	0.662	0.58
105_T	135_A	0.662	0.58
453_D	465_W	0.662	0.58
140_L	144_Q	0.658	0.58
479_R	484_D	0.658	0.58
520_L	532_L	0.658	0.58
589_Q	594_T	0.656	0.58
316_S	348_S	0.656	0.58
220_P	290_C	0.655	0.58
94_T	396_L	0.655	0.58
530_E	556_I	0.654	0.57
37_L	315_A	0.653	0.57
70_E	259_L	0.653	0.57
678_L	681_L	0.653	0.57
271_A	513_A	0.653	0.57
12_E	16_A	0.652	0.57
524_D	709_V	0.651	0.57
349_E	557_D	0.651	0.57
470_Q	475_R	0.650	0.57
299_D	539_Q	0.650	0.57
464_A	481_G	0.650	0.57
233_A	659_A	0.650	0.57
141_D	146_L	0.649	0.57
13_L	37_L	0.649	0.57
414_L	425_V	0.648	0.57
710_P	713_S	0.647	0.57
685_Q	688_R	0.647	0.57
538_L	546_A	0.646	0.57
484_D	487_L	0.646	0.57
627_T	634_R	0.645	0.56
473_L	479_R	0.644	0.56
641_A	651_A	0.642	0.56
688_R	692_D	0.642	0.56
625_N	628_A	0.642	0.56
513_A	566_L	0.641	0.56
43_A	72_L	0.641	0.56
139_L	168_L	0.641	0.56
349_E	354_Q	0.641	0.56
469_S	479_R	0.641	0.56
317_M	344_A	0.640	0.56
454_L	458_F	0.636	0.55
296_A	355_S	0.636	0.55
392_L	411_M	0.636	0.55
458_F	465_W	0.635	0.55
703_L	725_P	0.635	0.55
166_Q	557_D	0.635	0.55
142_V	321_A	0.634	0.55
63_N	67_R	0.633	0.55
641_A	650_P	0.633	0.55
318_T	346_A	0.631	0.55
217_L	271_A	0.631	0.55
84_M	247_G	0.630	0.55
584_A	603_P	0.630	0.55
45_P	118_G	0.629	0.55
201_A	228_V	0.629	0.55
490_P	558_E	0.629	0.55
86_A	348_S	0.628	0.54
78_D	91_G	0.626	0.54
135_A	139_L	0.626	0.54
186_R	207_M	0.625	0.54
141_D	369_C	0.625	0.54
594_T	597_V	0.624	0.54
400_E	405_S	0.624	0.54
284_I	556_I	0.624	0.54
51_I	121_I	0.623	0.54
660_A	664_W	0.623	0.54
206_E	209_R	0.623	0.54
477_N	485_S	0.622	0.54
31_A	143_Q	0.622	0.54
182_P	329_P	0.622	0.54
172_P	398_A	0.621	0.54
183_V	328_E	0.620	0.54
291_A	317_M	0.620	0.54
40_Q	43_A	0.619	0.53
104_L	130_L	0.619	0.53
119_L	151_K	0.619	0.53
483_A	486_S	0.618	0.53
247_G	324_A	0.618	0.53
560_V	598_Q	0.618	0.53
210_Q	213_G	0.618	0.53
195_R	207_M	0.617	0.53
475_R	483_A	0.614	0.53
424_L	640_A	0.614	0.53
284_I	301_R	0.613	0.53
294_R	309_T	0.613	0.53
25_L	230_E	0.612	0.53
453_D	457_A	0.611	0.52
69_A	74_E	0.611	0.52
391_R	394_Q	0.611	0.52
467_Q	478_V	0.610	0.52
104_L	120_V	0.610	0.52
277_T	281_I	0.610	0.52
632_Q	636_R	0.609	0.52
471_Q	482_E	0.607	0.52
416_N	424_L	0.605	0.52
694_G	702_E	0.604	0.52
365_L	404_L	0.603	0.52
178_G	378_L	0.603	0.52
361_L	390_K	0.603	0.52
480_G	484_D	0.602	0.51
427_A	436_A	0.602	0.51
279_L	440_A	0.602	0.51
457_A	462_Q	0.601	0.51
467_Q	473_L	0.600	0.51
62_R	66_Q	0.600	0.51
686_A	689_G	0.599	0.51
469_S	475_R	0.599	0.51
691_L	700_D	0.599	0.51
356_D	372_P	0.598	0.51
436_A	440_A	0.598	0.51
202_V	205_A	0.598	0.51
195_R	203_A	0.597	0.51
84_M	277_T	0.597	0.51
488_I	552_L	0.597	0.51
665_L	675_L	0.597	0.51
692_D	699_L	0.597	0.51
373_A	387_L	0.596	0.51
26_S	344_A	0.596	0.51
152_L	169_P	0.596	0.51
141_D	257_A	0.595	0.51
535_P	550_L	0.595	0.51
83_R	95_R	0.594	0.50
411_M	564_P	0.594	0.50
465_W	481_G	0.593	0.50
458_F	464_A	0.593	0.50
258_I	269_V	0.592	0.50
103_V	107_M	0.591	0.50
562_R	657_L	0.590	0.50
308_I	312_V	0.590	0.50
53_L	68_L	0.590	0.50
315_A	348_S	0.590	0.50
411_M	520_L	0.590	0.50
83_R	530_E	0.589	0.50
626_W	683_I	0.589	0.50
295_V	348_S	0.588	0.50
404_L	444_E	0.588	0.50
468_R	474_K	0.587	0.50
92_P	406_A	0.587	0.50
477_N	481_G	0.587	0.50
109_Q	136_L	0.586	0.50
399_L	441_A	0.586	0.50
696_Q	700_D	0.586	0.50
493_A	500_I	0.585	0.49
423_M	436_A	0.585	0.49
429_N	433_A	0.585	0.49
87_Q	251_L	0.584	0.49
467_Q	474_K	0.582	0.49
420_L	424_L	0.582	0.49
580_G	619_K	0.582	0.49
304_L	512_L	0.580	0.49
248_A	274_I	0.580	0.49
222_V	248_A	0.580	0.49
423_M	496_F	0.579	0.49
148_D	510_Y	0.579	0.49
517_G	545_D	0.579	0.49
416_N	421_A	0.579	0.49
206_E	211_E	0.578	0.49
279_L	282_E	0.578	0.49
510_Y	515_G	0.578	0.49
405_S	408_G	0.577	0.48
200_V	290_C	0.576	0.48
214_S	284_I	0.576	0.48
367_W	693_W	0.576	0.48
45_P	48_N	0.576	0.48
470_Q	485_S	0.575	0.48
222_V	226_Q	0.574	0.48
359_G	418_P	0.574	0.48
34_S	68_L	0.574	0.48
68_L	80_V	0.573	0.48
300_P	388_A	0.571	0.48
638_L	652_V	0.571	0.48
455_G	459_S	0.571	0.48
207_M	211_E	0.571	0.48
632_Q	639_C	0.571	0.48
42_L	96_L	0.570	0.48
519_M	527_S	0.570	0.48
46_G	95_R	0.569	0.48
217_L	290_C	0.569	0.48
672_V	675_L	0.569	0.48
29_T	34_S	0.567	0.47
582_L	611_A	0.566	0.47
101_E	125_F	0.566	0.47
299_D	302_T	0.566	0.47
276_E	316_S	0.565	0.47
505_G	508_G	0.565	0.47
120_V	329_P	0.565	0.47
220_P	224_E	0.565	0.47
624_L	679_K	0.565	0.47
64_V	68_L	0.565	0.47
360_L	372_P	0.564	0.47
67_R	546_A	0.563	0.47
629_E	685_Q	0.563	0.47
415_G	678_L	0.562	0.47
139_L	449_M	0.562	0.47
626_W	630_A	0.561	0.47
399_L	413_A	0.560	0.46
39_L	125_F	0.560	0.46
26_S	173_V	0.559	0.46
708_T	713_S	0.559	0.46
107_M	125_F	0.559	0.46
559_L	595_V	0.557	0.46
39_L	183_V	0.557	0.46
463_P	468_R	0.555	0.46
639_C	642_K	0.555	0.46
421_A	677_G	0.555	0.46
609_H	670_T	0.555	0.46
112_P	271_A	0.554	0.46
148_D	693_W	0.554	0.46
554_V	563_C	0.554	0.46
613_L	665_L	0.554	0.46
500_I	663_T	0.553	0.46
633_L	638_L	0.553	0.46
372_P	502_R	0.553	0.46
226_Q	246_Y	0.553	0.46
195_R	202_V	0.553	0.46
15_T	18_D	0.551	0.45
398_A	422_A	0.551	0.45
339_E	343_R	0.551	0.45
181_F	641_A	0.551	0.45
304_L	538_L	0.551	0.45
230_E	234_S	0.550	0.45
438_K	462_Q	0.549	0.45
70_E	196_F	0.549	0.45
470_Q	482_E	0.548	0.45
187_Y	314_Q	0.548	0.45
420_L	444_E	0.548	0.45
460_R	464_A	0.548	0.45
200_V	219_L	0.547	0.45
424_L	515_G	0.547	0.45
27_A	31_A	0.547	0.45
54_L	122_L	0.546	0.45
501_A	513_A	0.546	0.45
154_I	167_M	0.544	0.45
704_P	719_Y	0.544	0.45
471_Q	477_N	0.544	0.45
311_R	345_A	0.544	0.45
633_L	685_Q	0.543	0.44
143_Q	151_K	0.543	0.44
364_L	372_P	0.542	0.44
691_L	694_G	0.542	0.44
612_M	615_G	0.542	0.44
65_A	77_G	0.542	0.44
624_L	664_W	0.542	0.44
561_Q	564_P	0.541	0.44
180_S	183_V	0.541	0.44
9_V	23_V	0.540	0.44
249_L	269_V	0.540	0.44
683_I	689_G	0.540	0.44
235_R	240_V	0.540	0.44
164_L	174_V	0.539	0.44
236_I	239_D	0.539	0.44
601_A	671_G	0.539	0.44
695_M	698_R	0.538	0.44
103_V	135_A	0.538	0.44
185_R	188_L	0.538	0.44
635_L	667_P	0.537	0.44
689_G	697_Q	0.536	0.44
686_A	694_G	0.536	0.44
197_D	201_A	0.536	0.44
691_L	695_M	0.536	0.44
627_T	682_D	0.535	0.44
407_Q	673_H	0.535	0.44
70_E	255_R	0.534	0.43
138_L	360_L	0.534	0.43
29_T	64_V	0.534	0.43
640_A	644_L	0.534	0.43
574_E	583_K	0.533	0.43
137_A	376_S	0.533	0.43
511_Q	517_G	0.533	0.43
223_G	448_R	0.532	0.43
285_R	331_I	0.532	0.43
46_G	151_K	0.532	0.43
20_A	170_E	0.531	0.43
15_T	402_E	0.531	0.43
627_T	631_E	0.530	0.43
403_R	429_N	0.530	0.43
668_H	686_A	0.530	0.43
277_T	372_P	0.529	0.43
39_L	54_L	0.528	0.43
636_R	687_L	0.527	0.43
467_Q	482_E	0.527	0.43
461_N	469_S	0.527	0.43
243_C	267_K	0.527	0.43
510_Y	513_A	0.527	0.43
274_I	277_T	0.527	0.43
166_Q	380_Q	0.527	0.43
242_L	548_I	0.526	0.42
630_A	683_I	0.526	0.42
457_A	465_W	0.526	0.42
80_V	171_A	0.525	0.42
3_S	36_W	0.525	0.42
510_Y	530_E	0.524	0.42
32_G	38_P	0.524	0.42
33_K	38_P	0.524	0.42
426_S	491_L	0.524	0.42
171_A	392_L	0.524	0.42
444_E	656_S	0.524	0.42
354_Q	422_A	0.523	0.42
649_W	699_L	0.523	0.42
47_I	119_L	0.522	0.42
201_A	208_L	0.522	0.42
125_F	159_L	0.521	0.42
642_K	666_L	0.521	0.42
465_W	475_R	0.521	0.42
214_S	258_I	0.521	0.42
154_I	533_I	0.521	0.42
120_V	135_A	0.520	0.42
95_R	500_I	0.520	0.42
83_R	161_N	0.520	0.42
52_I	117_V	0.520	0.42
570_S	587_R	0.520	0.42
449_M	524_D	0.519	0.42
30_G	33_K	0.519	0.42
76_P	84_M	0.518	0.42
24_L	379_D	0.518	0.42
189_P	333_L	0.518	0.42
614_N	618_D	0.517	0.41
46_G	49_G	0.516	0.41
164_L	378_L	0.516	0.41
395_M	437_A	0.516	0.41
671_G	679_K	0.515	0.41
203_A	208_L	0.515	0.41
290_C	514_N	0.515	0.41
257_A	383_V	0.514	0.41
257_A	260_P	0.514	0.41
454_L	461_N	0.514	0.41
468_R	473_L	0.513	0.41
443_L	535_P	0.513	0.41
54_L	104_L	0.513	0.41
190_L	194_Q	0.512	0.41
69_A	526_L	0.511	0.41
306_R	423_M	0.510	0.41
469_S	480_G	0.510	0.41
154_I	488_I	0.510	0.41
427_A	433_A	0.510	0.41
173_V	347_Q	0.509	0.41
440_A	572_T	0.509	0.41
288_V	682_D	0.508	0.40
379_D	400_E	0.508	0.40
83_R	110_R	0.508	0.40
7_A	71_L	0.508	0.40
397_G	426_S	0.508	0.40
633_L	687_L	0.508	0.40
181_F	403_R	0.507	0.40
142_V	147_R	0.507	0.40
108_I	551_A	0.507	0.40
503_R	508_G	0.507	0.40
242_L	371_D	0.507	0.40
37_L	155_M	0.506	0.40
422_A	494_G	0.506	0.40
69_A	81_G	0.506	0.40
563_C	590_I	0.505	0.40
707_Y	712_G	0.504	0.40
9_V	25_L	0.504	0.40
62_R	84_M	0.504	0.40
366_Q	409_Q	0.504	0.40
456_V	463_P	0.503	0.40
9_V	230_E	0.503	0.40
7_A	67_R	0.502	0.40
474_K	479_R	0.502	0.40
39_L	98_V	0.501	0.40
599_P	702_E	0.501	0.40
149_D	597_V	0.501	0.40
45_P	49_G	0.501	0.40
50_K	83_R	0.501	0.40
635_L	720_H	0.500	0.39
396_L	411_M	0.500	0.39
560_V	567_V	0.500	0.39
692_D	698_R	0.500	0.39
433_A	437_A	0.500	0.39

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2xauA	1	0.7219	100	0.556	Contact Map
4bujA	1	0.6527	100	0.733	Contact Map
4cbhA	1	0.4574	100	0.76	Contact Map
2va8A	1	0.7058	100	0.761	Contact Map
5agaA	4	0.7553	100	0.762	Contact Map
2zj8A	2	0.7182	100	0.764	Contact Map
2whxA	1	0.5253	100	0.772	Contact Map
2p6rA	1	0.7194	100	0.773	Contact Map
4f92B	1	0.8529	100	0.779	Contact Map
3rc3A	1	0.5451	100	0.784	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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