GREMLIN Database
HRPB - ATP-dependent RNA helicase HrpB
UniProt: P37024 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG12329
Length: 809 (714)
Sequences: 2745 (1778)
Seq/√Len: 66.5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
185_R321_A4.3601.00
7_A36_W3.8991.00
78_D93_N3.8111.00
241_L265_M3.6361.00
120_V139_L3.6051.00
398_A411_M3.5831.00
411_M421_A3.5261.00
426_S429_N3.3391.00
34_S64_V3.3291.00
407_Q422_A3.2511.00
75_K78_D3.2321.00
321_A332_S3.2001.00
74_E79_T3.1751.00
580_G672_V3.1491.00
314_Q346_A3.1231.00
534_A551_A3.0981.00
285_R328_E3.0881.00
604_S607_E3.0321.00
706_H714_R2.9541.00
653_D656_S2.9011.00
692_D695_M2.8331.00
586_R598_Q2.8041.00
501_A518_A2.8001.00
52_I99_V2.7991.00
585_W597_V2.7971.00
200_V217_L2.6871.00
219_L270_L2.6301.00
9_V174_V2.6011.00
25_L37_L2.5961.00
655_E659_A2.5871.00
502_R531_W2.5731.00
199_A203_A2.5461.00
66_Q255_R2.5291.00
366_Q404_L2.5161.00
709_V715_I2.5001.00
556_I560_V2.4951.00
79_T95_R2.4861.00
631_E634_R2.4681.00
49_G118_G2.4551.00
371_D374_Q2.4551.00
229_Q270_L2.4531.00
186_R331_I2.4281.00
14_L40_Q2.4201.00
709_V713_S2.3781.00
13_L23_V2.3521.00
200_V204_T2.3391.00
504_R517_G2.3061.00
560_V588_L2.2521.00
410_K428_K2.2391.00
510_Y520_L2.2211.00
163_R379_D2.2091.00
21_P143_Q2.2031.00
47_I118_G2.1971.00
205_A235_R2.1951.00
312_V317_M2.1901.00
83_R88_N2.1881.00
83_R107_M2.1741.00
297_R310_Q2.1711.00
183_V325_G2.1531.00
67_R71_L2.1441.00
637_L652_V2.1221.00
634_R654_D2.0871.00
68_L98_V2.0801.00
651_A656_S2.0651.00
569_Q586_R2.0531.00
194_Q202_V2.0441.00
14_L44_H2.0381.00
634_R638_L2.0221.00
682_D685_Q2.0201.00
26_S161_N2.0101.00
318_T321_A2.0011.00
365_L399_L2.0011.00
49_G116_G1.9941.00
217_L288_V1.9931.00
587_R594_T1.9911.00
200_V228_V1.9901.00
420_L440_A1.9811.00
273_N312_V1.9511.00
206_E210_Q1.9461.00
518_A548_I1.9431.00
24_L164_L1.9381.00
617_R662_E1.9351.00
214_S261_A1.9271.00
46_G119_L1.9071.00
615_G619_K1.9011.00
188_L206_E1.8861.00
296_A305_T1.8761.00
571_D586_R1.8721.00
9_V12_E1.8711.00
708_T714_R1.8511.00
221_G224_E1.8421.00
576_D583_K1.8171.00
707_Y717_I1.8161.00
372_P386_L1.8131.00
394_Q400_E1.8061.00
15_T19_C1.8061.00
660_A663_T1.8051.00
166_Q170_E1.8011.00
229_Q233_A1.8001.00
479_R482_E1.7991.00
698_R701_S1.7991.00
12_E15_T1.7901.00
475_R479_R1.7841.00
207_M333_L1.7821.00
208_L268_V1.7731.00
611_A615_G1.7691.00
336_I341_A1.7671.00
36_W71_L1.7461.00
26_S175_I1.7451.00
492_L533_I1.7431.00
6_V36_W1.7361.00
681_L686_A1.7311.00
267_K281_I1.7271.00
520_L551_A1.7261.00
232_L242_L1.7221.00
472_L475_R1.7181.00
295_V349_E1.7080.99
215_L268_V1.7070.99
630_A633_L1.7040.99
318_T341_A1.6960.99
476_L479_R1.6900.99
338_K342_E1.6890.99
471_Q474_K1.6880.99
361_L386_L1.6730.99
457_A461_N1.6710.99
198_D231_Q1.6560.99
503_R530_E1.6520.99
456_V460_R1.6510.99
46_G118_G1.6510.99
22_Q143_Q1.6430.99
204_T217_L1.6350.99
125_F154_I1.6250.99
50_K97_E1.6150.99
203_A207_M1.6140.99
82_Y87_Q1.5930.99
501_A532_L1.5890.99
640_A703_L1.5870.99
250_S253_D1.5830.99
472_L479_R1.5830.99
475_R482_E1.5810.99
273_N293_E1.5670.99
220_P292_Q1.5650.99
267_K282_E1.5640.99
426_S430_D1.5630.99
317_M336_I1.5590.99
341_A344_A1.5590.99
462_Q465_W1.5590.99
67_R70_E1.5560.99
426_S494_G1.5450.99
471_Q475_R1.5430.99
251_L255_R1.5410.99
489_A552_L1.5400.99
222_V246_Y1.5320.99
548_I551_A1.5270.99
244_P249_L1.5230.99
510_Y527_S1.5190.99
204_T268_V1.5180.99
567_V588_L1.5150.99
311_R344_A1.5150.99
258_I282_E1.5150.99
129_S132_A1.5150.99
453_D458_F1.4980.99
109_Q363_E1.4980.99
475_R478_V1.4970.99
502_R530_E1.4960.99
69_A77_G1.4940.99
639_C643_W1.4850.99
400_E403_R1.4850.99
39_L72_L1.4790.99
80_V96_L1.4700.98
360_L377_W1.4700.98
509_R545_D1.4550.98
684_Y688_R1.4520.98
686_A690_L1.4450.98
199_A202_V1.4410.98
422_A426_S1.4390.98
10_L40_Q1.4330.98
674_S677_G1.4320.98
473_L476_L1.4290.98
555_D558_E1.4280.98
386_L390_K1.4200.98
83_R97_E1.4160.98
113_E146_L1.4140.98
25_L153_L1.4100.98
567_V595_V1.4000.98
16_A174_V1.3990.98
232_L270_L1.3960.98
24_L165_Q1.3940.98
203_A206_E1.3910.98
165_Q169_P1.3890.98
461_N465_W1.3880.98
419_R498_D1.3850.98
140_L168_L1.3800.98
457_A460_R1.3760.98
569_Q588_L1.3670.98
673_H677_G1.3620.97
162_D166_Q1.3570.97
559_L567_V1.3550.97
468_R471_Q1.3500.97
202_V206_E1.3460.97
424_L440_A1.3410.97
617_R661_L1.3360.97
538_L549_L1.3340.97
698_R702_E1.3320.97
204_T207_M1.3250.97
10_L43_A1.3250.97
253_D256_K1.3230.97
200_V206_E1.3180.97
88_N107_M1.3170.97
122_L139_L1.3160.97
229_Q244_P1.3150.97
534_A548_I1.3130.97
454_L457_A1.3080.97
186_R210_Q1.3060.97
498_D513_A1.3000.97
194_Q197_D1.2980.97
90_V97_E1.2950.97
574_E585_W1.2940.97
512_L518_A1.2930.97
531_W593_L1.2910.96
261_A265_M1.2900.96
237_G240_V1.2890.96
213_G266_R1.2860.96
223_G227_R1.2830.96
53_L98_V1.2770.96
18_D44_H1.2760.96
633_L688_R1.2750.96
658_L662_E1.2750.96
16_A23_V1.2730.96
668_H689_G1.2690.96
261_A264_G1.2680.96
215_L286_L1.2680.96
143_Q152_L1.2680.96
285_R327_L1.2670.96
28_P177_E1.2580.96
68_L96_L1.2560.96
634_R637_L1.2560.96
423_M427_A1.2510.96
609_H613_L1.2500.96
243_C256_K1.2490.96
537_L546_A1.2470.96
383_V387_L1.2450.96
460_R463_P1.2390.96
621_L658_L1.2350.95
633_L637_L1.2340.95
482_E486_S1.2320.95
510_Y529_H1.2310.95
603_P608_L1.2300.95
72_L80_V1.2290.95
198_D201_A1.2270.95
125_F164_L1.2270.95
371_D390_K1.2240.95
490_P561_Q1.2230.95
472_L476_L1.2210.95
587_R597_V1.2210.95
208_L240_V1.2170.95
129_S277_T1.2140.95
609_H666_L1.2110.95
436_A488_I1.2070.95
509_R517_G1.2040.95
479_R486_S1.2030.95
241_L261_A1.1990.95
570_S589_Q1.1950.95
199_A206_E1.1950.95
291_A336_I1.1930.95
478_V482_E1.1870.94
282_E327_L1.1770.94
14_L18_D1.1750.94
241_L267_K1.1750.94
200_V203_A1.1730.94
201_A231_Q1.1730.94
211_E285_R1.1700.94
463_P466_Q1.1690.94
469_S473_L1.1670.94
201_A204_T1.1620.94
17_L23_V1.1610.94
211_E331_I1.1600.94
83_R103_V1.1560.94
468_R472_L1.1490.93
50_K116_G1.1480.93
186_R211_E1.1480.93
430_D491_L1.1450.93
284_I327_L1.1430.93
139_L152_L1.1380.93
671_G674_S1.1340.93
373_A383_V1.1330.93
52_I120_V1.1320.93
490_P562_R1.1310.93
3_S7_A1.1240.93
211_E286_L1.1230.93
197_D227_R1.1220.93
201_A205_A1.1180.92
107_M117_V1.1100.92
572_T587_R1.1040.92
657_L664_W1.1010.92
478_V483_A1.1010.92
167_M376_S1.0970.92
293_E312_V1.0960.92
241_L256_K1.0960.92
721_E724_P1.0960.92
144_Q148_D1.0950.92
364_L377_W1.0920.91
390_K399_L1.0920.91
637_L641_A1.0910.91
502_R593_L1.0910.91
11_P15_T1.0890.91
477_N480_G1.0890.91
439_I488_I1.0840.91
315_A347_Q1.0830.91
470_Q473_L1.0810.91
195_R206_E1.0780.91
652_V690_L1.0770.91
214_S283_G1.0760.91
365_L390_K1.0730.91
214_S328_E1.0700.91
215_L288_V1.0700.91
637_L651_A1.0680.91
692_D696_Q1.0670.91
639_C703_L1.0650.90
74_E78_D1.0630.90
473_L478_V1.0610.90
111_D115_S1.0560.90
161_N173_V1.0530.90
228_V290_C1.0520.90
513_A593_L1.0500.90
458_F462_Q1.0480.90
101_E129_S1.0470.90
353_L379_D1.0470.90
462_Q472_L1.0460.90
105_T131_Q1.0460.90
503_R510_Y1.0450.90
688_R696_Q1.0450.90
382_P385_N1.0440.90
351_E355_S1.0430.89
305_T355_S1.0420.89
477_N482_E1.0420.89
472_L477_N1.0390.89
471_Q478_V1.0380.89
482_E485_S1.0330.89
257_A267_K1.0330.89
184_E331_I1.0330.89
162_D173_V1.0320.89
214_S243_C1.0310.89
226_Q229_Q1.0300.89
717_I725_P1.0280.89
101_E105_T1.0230.89
165_Q173_V1.0210.88
462_Q466_Q1.0210.88
183_V332_S1.0200.88
612_M616_I1.0200.88
246_Y249_L1.0190.88
160_D347_Q1.0190.88
203_A333_L1.0180.88
500_I559_L1.0180.88
500_I590_I1.0170.88
419_R499_R1.0150.88
628_A631_E1.0130.88
519_M545_D1.0120.88
219_L290_C1.0120.88
84_M251_L1.0120.88
204_T232_L1.0100.88
469_S472_L1.0090.88
23_V153_L1.0060.88
9_V16_A1.0060.88
313_S348_S1.0050.88
645_P648_D1.0040.88
72_L79_T1.0030.88
286_L333_L1.0030.88
199_A204_T1.0030.88
203_A217_L1.0020.88
571_D607_E1.0000.87
476_L480_G0.9970.87
201_A206_E0.9950.87
610_Q614_N0.9930.87
531_W556_I0.9890.87
529_H553_L0.9870.87
52_I97_E0.9870.87
134_L364_L0.9840.87
211_E328_E0.9820.86
358_S392_L0.9760.86
204_T208_L0.9750.86
536_L549_L0.9750.86
53_L121_I0.9740.86
97_E107_M0.9740.86
432_E491_L0.9720.86
474_K477_N0.9720.86
414_L421_A0.9710.86
64_V277_T0.9700.86
113_E142_V0.9670.86
207_M331_I0.9650.85
612_M675_L0.9640.85
185_R318_T0.9600.85
576_D599_P0.9590.85
314_Q318_T0.9590.85
202_V207_M0.9590.85
476_L483_A0.9580.85
196_F200_V0.9560.85
705_A716_A0.9550.85
555_D559_L0.9550.85
622_S627_T0.9530.85
134_L138_L0.9480.84
585_W599_P0.9480.84
709_V712_G0.9480.84
297_R308_I0.9470.84
468_R475_R0.9400.84
706_H716_A0.9390.84
656_S660_A0.9390.84
582_L608_L0.9390.84
48_N118_G0.9370.84
502_R594_T0.9330.84
42_L79_T0.9320.83
511_Q593_L0.9300.83
606_D610_Q0.9280.83
214_S267_K0.9260.83
217_L268_V0.9250.83
83_R116_G0.9240.83
286_L331_I0.9240.83
142_V148_D0.9220.83
588_L596_K0.9210.83
423_M495_A0.9210.83
77_G81_G0.9190.83
292_Q382_P0.9190.83
492_L535_P0.9190.83
268_V288_V0.9180.83
197_D228_V0.9160.82
36_W67_R0.9130.82
91_G94_T0.9120.82
240_V268_V0.9110.82
154_I168_L0.9090.82
229_Q242_L0.9090.82
471_Q479_R0.9070.82
273_N316_S0.9040.82
185_R334_H0.9040.82
474_K478_V0.9040.82
274_I548_I0.9020.81
665_L669_M0.8980.81
31_A176_S0.8980.81
637_L649_W0.8970.81
162_D175_I0.8970.81
500_I554_V0.8930.81
54_L101_E0.8930.81
84_M87_Q0.8910.81
189_P337_A0.8910.81
392_L419_R0.8890.80
140_L376_S0.8890.80
10_L14_L0.8890.80
366_Q412_A0.8890.80
392_L498_D0.8880.80
154_I164_L0.8860.80
423_M440_A0.8840.80
641_A649_W0.8840.80
41_L119_L0.8840.80
195_R198_D0.8830.80
59_L251_L0.8820.80
296_A308_I0.8820.80
687_L690_L0.8820.80
406_A409_Q0.8780.80
201_A207_M0.8780.80
8_A12_E0.8760.79
394_Q399_L0.8760.79
554_V559_L0.8760.79
636_R688_R0.8740.79
467_Q477_N0.8710.79
472_L478_V0.8710.79
50_K107_M0.8690.79
479_R485_S0.8680.79
9_V13_L0.8660.79
62_R255_R0.8660.79
501_A512_L0.8650.79
15_T20_A0.8640.79
483_A487_L0.8640.79
44_H96_L0.8620.78
138_L377_W0.8620.78
13_L176_S0.8620.78
336_I344_A0.8620.78
239_D265_M0.8610.78
456_V459_S0.8590.78
190_L196_F0.8590.78
634_R651_A0.8550.78
627_T630_A0.8540.78
559_L563_C0.8530.78
207_M210_Q0.8530.78
188_L203_A0.8510.77
629_E632_Q0.8510.77
198_D206_E0.8510.77
428_K433_A0.8500.77
564_P567_V0.8500.77
34_S546_A0.8490.77
186_R333_L0.8470.77
469_S477_N0.8440.77
450_G459_S0.8440.77
361_L364_L0.8430.77
469_S478_V0.8400.77
261_A267_K0.8400.77
34_S37_L0.8400.77
706_H709_V0.8370.76
370_S403_R0.8360.76
304_L546_A0.8350.76
198_D202_V0.8350.76
36_W40_Q0.8350.76
207_M286_L0.8350.76
359_G417_D0.8340.76
430_D490_P0.8330.76
479_R483_A0.8320.76
421_A424_L0.8310.76
617_R659_A0.8290.76
273_N296_A0.8280.76
660_A690_L0.8280.76
39_L68_L0.8280.76
494_G562_R0.8270.75
504_R511_Q0.8260.75
140_L143_Q0.8260.75
644_L649_W0.8240.75
314_Q341_A0.8240.75
187_Y341_A0.8230.75
165_Q171_A0.8220.75
579_Q583_K0.8210.75
672_V677_G0.8210.75
511_Q592_Q0.8210.75
612_M672_V0.8210.75
650_P692_D0.8210.75
646_E649_W0.8170.75
140_L167_M0.8170.75
269_V284_I0.8170.75
349_E353_L0.8160.74
469_S474_K0.8150.74
108_I135_A0.8150.74
502_R511_Q0.8150.74
188_L333_L0.8140.74
640_A702_E0.8140.74
638_L642_K0.8110.74
196_F199_A0.8110.74
119_L153_L0.8110.74
252_N256_K0.8100.74
521_D547_R0.8090.74
273_N354_Q0.8090.74
68_L71_L0.8080.74
295_V310_Q0.8080.74
195_R199_A0.8060.74
622_S631_E0.8040.73
144_Q376_S0.8020.73
641_A648_D0.8010.73
313_S316_S0.8000.73
228_V231_Q0.8000.73
708_T712_G0.8000.73
212_S328_E0.7990.73
83_R90_V0.7990.73
629_E684_Y0.7980.73
683_I686_A0.7970.73
705_A714_R0.7970.73
13_L25_L0.7950.73
327_L531_W0.7920.72
481_G485_S0.7900.72
249_L253_D0.7890.72
478_V485_S0.7870.72
670_T674_S0.7860.72
200_V207_M0.7840.71
11_P14_L0.7840.71
518_A534_A0.7820.71
478_V481_G0.7820.71
34_S444_E0.7810.71
312_V344_A0.7800.71
613_L617_R0.7780.71
437_A441_A0.7780.71
63_N258_I0.7770.71
205_A234_S0.7770.71
619_K623_V0.7760.71
54_L125_F0.7740.70
631_E635_L0.7740.70
191_P194_Q0.7710.70
86_A214_S0.7700.70
358_S417_D0.7700.70
50_K90_V0.7680.70
498_D533_I0.7680.70
21_P151_K0.7670.70
496_F499_R0.7650.70
491_L494_G0.7650.70
220_P367_W0.7630.69
137_A375_M0.7630.69
649_W652_V0.7620.69
392_L396_L0.7610.69
626_W654_D0.7610.69
140_L169_P0.7600.69
59_L98_V0.7590.69
23_V174_V0.7580.69
219_L228_V0.7560.69
77_G91_G0.7560.69
512_L537_L0.7540.68
199_A207_M0.7540.68
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380_Q694_G0.7500.68
261_A269_V0.7500.68
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105_T363_E0.7460.68
66_Q76_P0.7450.68
519_M547_R0.7440.67
386_L399_L0.7430.67
6_V23_V0.7430.67
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101_E131_Q0.7400.67
688_R700_D0.7400.67
531_W559_L0.7400.67
641_A646_E0.7380.67
225_I270_L0.7370.67
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635_L639_C0.7350.66
352_I381_P0.7350.66
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293_E348_S0.7200.65
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465_W472_L0.7190.65
427_A633_L0.7180.65
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460_R466_Q0.7150.64
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679_K707_Y0.7130.64
192_A197_D0.7130.64
25_L41_L0.7110.64
582_L615_G0.7110.64
240_V266_R0.7100.64
338_K341_A0.7100.64
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527_S547_R0.7070.63
141_D374_Q0.7060.63
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130_L357_L0.7020.63
31_A178_G0.7020.63
469_S476_L0.7000.63
208_L266_R0.7000.63
461_N464_A0.6990.63
467_Q476_L0.6980.62
169_P172_P0.6970.62
258_I281_I0.6960.62
577_D619_K0.6950.62
277_T316_S0.6950.62
664_W667_P0.6930.62
694_G701_S0.6920.62
207_M213_G0.6920.62
9_V176_S0.6910.62
270_L415_G0.6910.62
407_Q426_S0.6910.62
500_I561_Q0.6890.61
481_G486_S0.6890.61
458_F461_N0.6890.61
107_M110_R0.6880.61
51_I153_L0.6880.61
397_G400_E0.6870.61
67_R98_V0.6860.61
556_I593_L0.6850.61
42_L51_I0.6850.61
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571_D600_L0.6840.61
394_Q401_G0.6840.61
470_Q479_R0.6820.61
258_I267_K0.6820.61
535_P552_L0.6800.60
642_K722_D0.6790.60
476_L482_E0.6790.60
630_A684_Y0.6780.60
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634_R690_L0.6770.60
99_V103_V0.6760.60
605_E608_L0.6750.60
149_D363_E0.6750.60
242_L520_L0.6750.60
465_W468_R0.6720.60
446_P449_M0.6710.59
236_I242_L0.6700.59
17_L41_L0.6700.59
288_V557_D0.6690.59
13_L174_V0.6680.59
370_S374_Q0.6680.59
211_E214_S0.6670.59
632_Q705_A0.6670.59
467_Q471_Q0.6660.59
469_S553_L0.6660.59
676_R680_S0.6660.59
627_T633_L0.6650.59
607_E610_Q0.6640.59
31_A179_R0.6640.59
672_V681_L0.6630.59
677_G681_L0.6630.59
505_G510_Y0.6620.58
105_T135_A0.6620.58
453_D465_W0.6620.58
140_L144_Q0.6580.58
479_R484_D0.6580.58
520_L532_L0.6580.58
589_Q594_T0.6560.58
316_S348_S0.6560.58
220_P290_C0.6550.58
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530_E556_I0.6540.57
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271_A513_A0.6530.57
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473_L479_R0.6440.56
641_A651_A0.6420.56
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139_L168_L0.6410.56
349_E354_Q0.6410.56
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317_M344_A0.6400.56
454_L458_F0.6360.55
296_A355_S0.6360.55
392_L411_M0.6360.55
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703_L725_P0.6350.55
166_Q557_D0.6350.55
142_V321_A0.6340.55
63_N67_R0.6330.55
641_A650_P0.6330.55
318_T346_A0.6310.55
217_L271_A0.6310.55
84_M247_G0.6300.55
584_A603_P0.6300.55
45_P118_G0.6290.55
201_A228_V0.6290.55
490_P558_E0.6290.55
86_A348_S0.6280.54
78_D91_G0.6260.54
135_A139_L0.6260.54
186_R207_M0.6250.54
141_D369_C0.6250.54
594_T597_V0.6240.54
400_E405_S0.6240.54
284_I556_I0.6240.54
51_I121_I0.6230.54
660_A664_W0.6230.54
206_E209_R0.6230.54
477_N485_S0.6220.54
31_A143_Q0.6220.54
182_P329_P0.6220.54
172_P398_A0.6210.54
183_V328_E0.6200.54
291_A317_M0.6200.54
40_Q43_A0.6190.53
104_L130_L0.6190.53
119_L151_K0.6190.53
483_A486_S0.6180.53
247_G324_A0.6180.53
560_V598_Q0.6180.53
210_Q213_G0.6180.53
195_R207_M0.6170.53
475_R483_A0.6140.53
424_L640_A0.6140.53
284_I301_R0.6130.53
294_R309_T0.6130.53
25_L230_E0.6120.53
453_D457_A0.6110.52
69_A74_E0.6110.52
391_R394_Q0.6110.52
467_Q478_V0.6100.52
104_L120_V0.6100.52
277_T281_I0.6100.52
632_Q636_R0.6090.52
471_Q482_E0.6070.52
416_N424_L0.6050.52
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365_L404_L0.6030.52
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361_L390_K0.6030.52
480_G484_D0.6020.51
427_A436_A0.6020.51
279_L440_A0.6020.51
457_A462_Q0.6010.51
467_Q473_L0.6000.51
62_R66_Q0.6000.51
686_A689_G0.5990.51
469_S475_R0.5990.51
691_L700_D0.5990.51
356_D372_P0.5980.51
436_A440_A0.5980.51
202_V205_A0.5980.51
195_R203_A0.5970.51
84_M277_T0.5970.51
488_I552_L0.5970.51
665_L675_L0.5970.51
692_D699_L0.5970.51
373_A387_L0.5960.51
26_S344_A0.5960.51
152_L169_P0.5960.51
141_D257_A0.5950.51
535_P550_L0.5950.51
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411_M564_P0.5940.50
465_W481_G0.5930.50
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279_L282_E0.5780.49
510_Y515_G0.5780.49
405_S408_G0.5770.48
200_V290_C0.5760.48
214_S284_I0.5760.48
367_W693_W0.5760.48
45_P48_N0.5760.48
470_Q485_S0.5750.48
222_V226_Q0.5740.48
359_G418_P0.5740.48
34_S68_L0.5740.48
68_L80_V0.5730.48
300_P388_A0.5710.48
638_L652_V0.5710.48
455_G459_S0.5710.48
207_M211_E0.5710.48
632_Q639_C0.5710.48
42_L96_L0.5700.48
519_M527_S0.5700.48
46_G95_R0.5690.48
217_L290_C0.5690.48
672_V675_L0.5690.48
29_T34_S0.5670.47
582_L611_A0.5660.47
101_E125_F0.5660.47
299_D302_T0.5660.47
276_E316_S0.5650.47
505_G508_G0.5650.47
120_V329_P0.5650.47
220_P224_E0.5650.47
624_L679_K0.5650.47
64_V68_L0.5650.47
360_L372_P0.5640.47
67_R546_A0.5630.47
629_E685_Q0.5630.47
415_G678_L0.5620.47
139_L449_M0.5620.47
626_W630_A0.5610.47
399_L413_A0.5600.46
39_L125_F0.5600.46
26_S173_V0.5590.46
708_T713_S0.5590.46
107_M125_F0.5590.46
559_L595_V0.5570.46
39_L183_V0.5570.46
463_P468_R0.5550.46
639_C642_K0.5550.46
421_A677_G0.5550.46
609_H670_T0.5550.46
112_P271_A0.5540.46
148_D693_W0.5540.46
554_V563_C0.5540.46
613_L665_L0.5540.46
500_I663_T0.5530.46
633_L638_L0.5530.46
372_P502_R0.5530.46
226_Q246_Y0.5530.46
195_R202_V0.5530.46
15_T18_D0.5510.45
398_A422_A0.5510.45
339_E343_R0.5510.45
181_F641_A0.5510.45
304_L538_L0.5510.45
230_E234_S0.5500.45
438_K462_Q0.5490.45
70_E196_F0.5490.45
470_Q482_E0.5480.45
187_Y314_Q0.5480.45
420_L444_E0.5480.45
460_R464_A0.5480.45
200_V219_L0.5470.45
424_L515_G0.5470.45
27_A31_A0.5470.45
54_L122_L0.5460.45
501_A513_A0.5460.45
154_I167_M0.5440.45
704_P719_Y0.5440.45
471_Q477_N0.5440.45
311_R345_A0.5440.45
633_L685_Q0.5430.44
143_Q151_K0.5430.44
364_L372_P0.5420.44
691_L694_G0.5420.44
612_M615_G0.5420.44
65_A77_G0.5420.44
624_L664_W0.5420.44
561_Q564_P0.5410.44
180_S183_V0.5410.44
9_V23_V0.5400.44
249_L269_V0.5400.44
683_I689_G0.5400.44
235_R240_V0.5400.44
164_L174_V0.5390.44
236_I239_D0.5390.44
601_A671_G0.5390.44
695_M698_R0.5380.44
103_V135_A0.5380.44
185_R188_L0.5380.44
635_L667_P0.5370.44
689_G697_Q0.5360.44
686_A694_G0.5360.44
197_D201_A0.5360.44
691_L695_M0.5360.44
627_T682_D0.5350.44
407_Q673_H0.5350.44
70_E255_R0.5340.43
138_L360_L0.5340.43
29_T64_V0.5340.43
640_A644_L0.5340.43
574_E583_K0.5330.43
137_A376_S0.5330.43
511_Q517_G0.5330.43
223_G448_R0.5320.43
285_R331_I0.5320.43
46_G151_K0.5320.43
20_A170_E0.5310.43
15_T402_E0.5310.43
627_T631_E0.5300.43
403_R429_N0.5300.43
668_H686_A0.5300.43
277_T372_P0.5290.43
39_L54_L0.5280.43
636_R687_L0.5270.43
467_Q482_E0.5270.43
461_N469_S0.5270.43
243_C267_K0.5270.43
510_Y513_A0.5270.43
274_I277_T0.5270.43
166_Q380_Q0.5270.43
242_L548_I0.5260.42
630_A683_I0.5260.42
457_A465_W0.5260.42
80_V171_A0.5250.42
3_S36_W0.5250.42
510_Y530_E0.5240.42
32_G38_P0.5240.42
33_K38_P0.5240.42
426_S491_L0.5240.42
171_A392_L0.5240.42
444_E656_S0.5240.42
354_Q422_A0.5230.42
649_W699_L0.5230.42
47_I119_L0.5220.42
201_A208_L0.5220.42
125_F159_L0.5210.42
642_K666_L0.5210.42
465_W475_R0.5210.42
214_S258_I0.5210.42
154_I533_I0.5210.42
120_V135_A0.5200.42
95_R500_I0.5200.42
83_R161_N0.5200.42
52_I117_V0.5200.42
570_S587_R0.5200.42
449_M524_D0.5190.42
30_G33_K0.5190.42
76_P84_M0.5180.42
24_L379_D0.5180.42
189_P333_L0.5180.42
614_N618_D0.5170.41
46_G49_G0.5160.41
164_L378_L0.5160.41
395_M437_A0.5160.41
671_G679_K0.5150.41
203_A208_L0.5150.41
290_C514_N0.5150.41
257_A383_V0.5140.41
257_A260_P0.5140.41
454_L461_N0.5140.41
468_R473_L0.5130.41
443_L535_P0.5130.41
54_L104_L0.5130.41
190_L194_Q0.5120.41
69_A526_L0.5110.41
306_R423_M0.5100.41
469_S480_G0.5100.41
154_I488_I0.5100.41
427_A433_A0.5100.41
173_V347_Q0.5090.41
440_A572_T0.5090.41
288_V682_D0.5080.40
379_D400_E0.5080.40
83_R110_R0.5080.40
7_A71_L0.5080.40
397_G426_S0.5080.40
633_L687_L0.5080.40
181_F403_R0.5070.40
142_V147_R0.5070.40
108_I551_A0.5070.40
503_R508_G0.5070.40
242_L371_D0.5070.40
37_L155_M0.5060.40
422_A494_G0.5060.40
69_A81_G0.5060.40
563_C590_I0.5050.40
707_Y712_G0.5040.40
9_V25_L0.5040.40
62_R84_M0.5040.40
366_Q409_Q0.5040.40
456_V463_P0.5030.40
9_V230_E0.5030.40
7_A67_R0.5020.40
474_K479_R0.5020.40
39_L98_V0.5010.40
599_P702_E0.5010.40
149_D597_V0.5010.40
45_P49_G0.5010.40
50_K83_R0.5010.40
635_L720_H0.5000.39
396_L411_M0.5000.39
560_V567_V0.5000.39
692_D698_R0.5000.39
433_A437_A0.5000.39
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2xauA 1 0.7219 100 0.556 Contact Map
4bujA 1 0.6527 100 0.733 Contact Map
4cbhA 1 0.4574 100 0.76 Contact Map
2va8A 1 0.7058 100 0.761 Contact Map
5agaA 4 0.7553 100 0.762 Contact Map
2zj8A 2 0.7182 100 0.764 Contact Map
2whxA 1 0.5253 100 0.772 Contact Map
2p6rA 1 0.7194 100 0.773 Contact Map
4f92B 1 0.8529 100 0.779 Contact Map
3rc3A 1 0.5451 100 0.784 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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