CLCA - ECOLI - GREMLIN Contacts

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CLCA - H(+)/Cl(-) exchange transporter ClcA

UniProt:	P37019	Sequences: MKTDTPSLETPQAARLRRRQLIRQLLERDKTPLAILFMAAVVGTLVGLAAVAFDKGVAWLQNQRMGALVHTADNYPLLLTVAFLCSAVLAMFGYFLVRKYAPEAGGSGIPEIEGALEDQRPVRWWRVLPVKFFGGLGTLGGGMVLGREGPTVQIGGNIGRMVLDIFRLKGDEARHTLLATGAAAGLAAAFNAPLAGILFIIEEMRPQFRYTLISIKAVFIGVIMSTIMYRIFNHEVALIDVGKLSDAPLNTLWLYLILGIIFGIFGPIFNKWVLGMQDLLHRVHGGNITKWVLMGGAIGGLCGLLGFVAPATSGGGFNLIPIATAGNFSMGMLVFIFVARVITTLLCFSSGAPGGIFAPMLALGTVLGTAFGMVAVELFPQYHLEAGTFAIAGMGALLAASIRAPLTGIILVLEMTDNYQLILPMIITGLGATLLAQFTGGKPLYSAILARTLAKQEAEQLARSKAASASENT	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG12331
Length:	473 (404)
Sequences:	5288 (3708)
Seq/√Len:	184.5

ECOLI - CLCA CLCB YFEO
HALSA - Q9HPN8
SULSO - Q97U23

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
396_A	428_T	4.268	1.00
138_T	143_M	3.590	1.00
334_V	370_A	3.556	1.00
271_K	275_G	3.469	1.00
143_M	347_C	3.435	1.00
145_L	347_C	3.413	1.00
144_V	344_T	3.362	1.00
392_A	428_T	3.295	1.00
144_V	340_R	3.230	1.00
155_G	181_G	2.934	1.00
261_I	367_L	2.918	1.00
89_L	141_G	2.832	1.00
49_A	158_I	2.803	1.00
305_L	343_T	2.676	1.00
55_K	59_W	2.603	1.00
95_F	99_K	2.561	1.00
265_F	397_L	2.477	1.00
258_L	371_F	2.439	1.00
255_Y	392_A	2.426	1.00
275_G	279_L	2.416	1.00
90_A	94_Y	2.384	1.00
409_I	426_I	2.381	1.00
337_F	370_A	2.380	1.00
198_L	410_I	2.379	1.00
251_T	389_F	2.337	1.00
39_A	43_G	2.328	1.00
265_F	367_L	2.254	1.00
59_W	63_Q	2.246	1.00
272_W	345_L	2.245	1.00
263_G	435_L	2.107	1.00
399_A	429_G	2.083	1.00
301_L	346_L	2.053	1.00
275_G	278_D	2.051	1.00
138_T	145_L	2.043	1.00
259_G	263_G	2.037	1.00
320_I	365_T	2.026	1.00
306_G	313_S	2.014	1.00
47_G	51_V	1.993	1.00
42_V	46_V	1.987	1.00
138_T	352_A	1.984	1.00
330_M	370_A	1.970	1.00
276_M	349_S	1.957	1.00
128_L	157_N	1.935	1.00
266_G	400_A	1.926	1.00
360_M	401_S	1.924	1.00
86_S	90_A	1.918	1.00
280_L	350_S	1.917	1.00
96_L	100_Y	1.911	1.00
253_W	257_I	1.906	1.00
50_A	151_T	1.903	1.00
264_I	268_I	1.892	1.00
60_L	140_G	1.882	1.00
337_F	367_L	1.848	1.00
163_L	174_R	1.845	1.00
112_I	156_G	1.815	1.00
221_G	225_S	1.803	1.00
56_G	136_L	1.801	1.00
337_F	363_L	1.797	1.00
48_L	232_F	1.776	1.00
220_I	224_M	1.770	1.00
269_F	344_T	1.764	1.00
341_V	363_L	1.745	1.00
403_R	437_Q	1.727	1.00
86_S	89_L	1.716	1.00
161_M	165_I	1.706	1.00
262_F	367_L	1.697	1.00
256_L	431_G	1.689	1.00
91_M	94_Y	1.683	1.00
46_V	155_G	1.676	1.00
323_A	366_V	1.646	1.00
44_T	228_M	1.644	1.00
259_G	432_A	1.638	1.00
298_I	350_S	1.634	1.00
395_G	429_G	1.626	1.00
79_L	82_A	1.624	1.00
319_L	362_A	1.619	1.00
256_L	260_I	1.613	1.00
138_T	347_C	1.610	1.00
304_L	308_V	1.589	1.00
254_L	375_A	1.587	1.00
199_F	203_E	1.580	1.00
249_L	253_W	1.572	1.00
360_M	397_L	1.554	1.00
260_I	435_L	1.527	1.00
337_F	366_V	1.523	1.00
87_A	90_A	1.510	1.00
91_M	95_F	1.497	1.00
279_L	283_V	1.481	1.00
259_G	431_G	1.480	1.00
333_L	369_T	1.478	1.00
51_V	232_F	1.477	1.00
262_F	396_A	1.459	1.00
183_A	187_A	1.459	1.00
93_G	97_V	1.452	1.00
278_D	282_R	1.439	1.00
134_G	353_P	1.439	1.00
95_F	100_Y	1.433	1.00
258_L	262_F	1.419	1.00
413_L	422_I	1.419	1.00
183_A	200_I	1.417	1.00
132_F	154_I	1.417	1.00
255_Y	428_T	1.415	1.00
40_A	224_M	1.412	1.00
371_F	375_A	1.406	1.00
361_L	394_M	1.403	1.00
46_V	184_A	1.393	1.00
184_A	221_G	1.389	1.00
42_V	177_L	1.384	1.00
131_K	353_P	1.382	1.00
262_F	397_L	1.361	1.00
92_F	137_G	1.358	1.00
263_G	436_A	1.342	1.00
329_S	332_M	1.335	1.00
391_I	416_T	1.324	1.00
121_P	160_R	1.321	1.00
160_R	174_R	1.316	1.00
335_F	339_A	1.315	1.00
85_C	89_L	1.313	1.00
104_A	130_V	1.310	1.00
50_A	188_A	1.306	1.00
83_F	86_S	1.304	1.00
260_I	264_I	1.303	1.00
333_L	370_A	1.301	1.00
97_V	101_A	1.298	1.00
82_A	86_S	1.293	1.00
400_A	432_A	1.278	1.00
182_A	204_M	1.275	1.00
64_R	141_G	1.271	1.00
169_K	173_A	1.271	1.00
39_A	42_V	1.271	1.00
179_A	205_R	1.267	1.00
433_T	437_Q	1.260	1.00
374_V	378_L	1.258	1.00
398_L	408_G	1.253	1.00
311_A	314_G	1.250	1.00
398_L	402_I	1.246	1.00
309_A	339_A	1.245	1.00
48_L	52_A	1.243	1.00
179_A	218_V	1.242	1.00
365_T	390_A	1.238	1.00
129_P	133_F	1.238	1.00
276_M	345_L	1.234	1.00
180_T	221_G	1.220	1.00
369_T	390_A	1.217	1.00
225_S	229_Y	1.217	1.00
312_T	315_G	1.210	1.00
194_L	410_I	1.205	1.00
333_L	366_V	1.200	1.00
183_A	218_V	1.197	1.00
372_G	384_L	1.197	1.00
217_A	222_V	1.185	1.00
412_V	425_M	1.167	1.00
59_W	62_N	1.164	1.00
226_T	230_R	1.163	1.00
386_A	390_A	1.163	1.00
150_P	190_F	1.161	1.00
384_L	389_F	1.159	1.00
79_L	83_F	1.157	1.00
81_V	85_C	1.156	1.00
334_V	338_V	1.150	1.00
101_A	104_A	1.149	1.00
254_L	371_F	1.148	1.00
428_T	432_A	1.148	1.00
443_P	448_I	1.118	1.00
53_F	57_V	1.116	1.00
291_W	294_M	1.115	1.00
267_P	436_A	1.108	1.00
54_D	57_V	1.100	1.00
274_L	447_A	1.099	1.00
263_G	432_A	1.098	1.00
101_A	130_V	1.098	1.00
403_R	436_A	1.094	1.00
217_A	225_S	1.093	1.00
191_N	230_R	1.092	1.00
164_D	174_R	1.086	1.00
372_G	386_A	1.084	1.00
345_L	349_S	1.077	1.00
302_C	343_T	1.072	1.00
187_A	222_V	1.069	1.00
85_C	88_V	1.069	1.00
251_T	255_Y	1.068	1.00
316_G	362_A	1.066	1.00
230_R	235_E	1.064	1.00
94_Y	292_V	1.064	1.00
421_L	425_M	1.060	1.00
367_L	397_L	1.058	1.00
208_F	212_L	1.050	1.00
395_G	412_V	1.049	1.00
44_T	48_L	1.037	1.00
63_Q	67_A	1.036	1.00
94_Y	97_V	1.034	1.00
279_L	282_R	1.033	1.00
80_T	84_L	1.031	1.00
269_F	347_C	1.030	1.00
35_I	39_A	1.029	1.00
52_A	132_F	1.025	1.00
216_K	224_M	1.010	0.99
312_T	343_T	1.010	0.99
125_W	161_M	1.009	0.99
90_A	93_G	1.007	0.99
321_P	325_A	1.006	0.99
58_A	62_N	0.999	0.99
316_G	320_I	0.994	0.99
53_F	135_G	0.994	0.99
322_I	327_N	0.993	0.99
209_R	213_I	0.992	0.99
88_V	91_M	0.987	0.99
388_T	421_L	0.987	0.99
341_V	345_L	0.987	0.99
97_V	100_Y	0.983	0.99
107_S	110_P	0.978	0.99
267_P	439_T	0.973	0.99
222_V	226_T	0.972	0.99
80_T	83_F	0.970	0.99
389_F	393_G	0.968	0.99
91_M	296_G	0.965	0.99
250_N	254_L	0.963	0.99
94_Y	98_R	0.962	0.99
38_M	168_L	0.961	0.99
218_V	222_V	0.957	0.99
373_M	377_E	0.957	0.99
280_L	298_I	0.957	0.99
51_V	55_K	0.956	0.99
259_G	396_A	0.952	0.99
302_C	305_L	0.950	0.99
302_C	347_C	0.946	0.99
113_E	116_L	0.943	0.99
207_Q	213_I	0.941	0.99
49_A	53_F	0.937	0.99
299_G	303_G	0.936	0.99
110_P	113_E	0.932	0.99
52_A	56_G	0.929	0.99
32_P	35_I	0.928	0.99
310_P	313_S	0.927	0.99
236_V	240_D	0.927	0.99
372_G	389_F	0.926	0.99
106_G	131_K	0.926	0.99
124_W	161_M	0.925	0.99
331_G	335_F	0.918	0.99
189_A	203_E	0.913	0.99
277_Q	281_H	0.911	0.99
290_K	293_L	0.907	0.99
49_A	128_L	0.905	0.99
145_L	354_G	0.897	0.99
89_L	95_F	0.896	0.99
45_L	49_A	0.895	0.99
362_A	366_V	0.895	0.99
304_L	307_F	0.894	0.99
108_G	113_E	0.894	0.99
45_L	158_I	0.894	0.99
107_S	111_E	0.892	0.99
37_F	41_V	0.891	0.99
148_E	189_A	0.890	0.99
83_F	307_F	0.889	0.99
113_E	118_D	0.889	0.99
127_V	153_Q	0.887	0.99
402_I	445_Y	0.887	0.99
405_P	408_G	0.882	0.99
51_V	228_M	0.881	0.99
387_G	390_A	0.880	0.99
260_I	431_G	0.879	0.99
94_Y	295_G	0.879	0.99
272_W	341_V	0.875	0.99
409_I	429_G	0.875	0.99
39_A	46_V	0.871	0.98
114_G	449_L	0.869	0.98
323_A	369_T	0.866	0.98
114_G	118_D	0.864	0.98
45_L	162_V	0.861	0.98
89_L	97_V	0.860	0.98
155_G	159_G	0.857	0.98
108_G	149_G	0.855	0.98
222_V	229_Y	0.850	0.98
216_K	220_I	0.850	0.98
371_F	389_F	0.849	0.98
262_F	400_A	0.847	0.98
267_P	271_K	0.845	0.98
299_G	302_C	0.845	0.98
136_L	140_G	0.844	0.98
336_I	366_V	0.841	0.98
195_A	407_T	0.839	0.98
115_A	118_D	0.838	0.98
380_P	383_H	0.837	0.98
228_M	231_I	0.833	0.98
60_L	136_L	0.829	0.98
259_G	427_I	0.827	0.98
144_V	302_C	0.826	0.98
108_G	111_E	0.825	0.98
357_F	415_M	0.824	0.98
56_G	59_W	0.823	0.98
107_S	131_K	0.819	0.98
264_I	435_L	0.819	0.98
107_S	113_E	0.817	0.98
317_F	358_A	0.813	0.98
255_Y	388_T	0.812	0.98
131_K	185_G	0.810	0.98
369_T	386_A	0.809	0.98
293_L	297_A	0.808	0.97
218_V	224_M	0.806	0.97
257_I	371_F	0.806	0.97
280_L	284_H	0.805	0.97
207_Q	212_L	0.802	0.97
52_A	55_K	0.802	0.97
425_M	429_G	0.801	0.97
34_A	173_A	0.801	0.97
248_P	251_T	0.798	0.97
106_G	353_P	0.794	0.97
130_V	134_G	0.793	0.97
388_T	392_A	0.792	0.97
152_V	199_F	0.790	0.97
298_I	343_T	0.790	0.97
210_Y	213_I	0.789	0.97
116_L	204_M	0.788	0.97
407_T	411_L	0.785	0.97
143_M	352_A	0.784	0.97
224_M	227_I	0.783	0.97
290_K	294_M	0.781	0.97
85_C	90_A	0.779	0.97
217_A	220_I	0.779	0.97
151_T	358_A	0.777	0.97
266_G	401_S	0.777	0.97
268_I	341_V	0.777	0.97
53_F	154_I	0.776	0.97
182_A	361_L	0.775	0.97
402_I	415_M	0.774	0.97
86_S	299_G	0.774	0.97
64_R	85_C	0.773	0.97
300_G	305_L	0.770	0.97
87_A	299_G	0.768	0.97
196_G	408_G	0.768	0.97
87_A	296_G	0.767	0.97
191_N	226_T	0.766	0.97
196_G	200_I	0.765	0.97
89_L	137_G	0.765	0.97
57_V	147_R	0.762	0.96
309_A	335_F	0.761	0.96
109_I	152_V	0.756	0.96
207_Q	211_T	0.753	0.96
295_G	299_G	0.751	0.96
95_F	98_R	0.750	0.96
329_S	338_V	0.750	0.96
276_M	280_L	0.750	0.96
89_L	92_F	0.749	0.96
296_G	300_G	0.749	0.96
145_L	348_F	0.746	0.96
209_R	212_L	0.745	0.96
294_M	298_I	0.743	0.96
268_I	272_W	0.743	0.96
60_L	64_R	0.743	0.96
40_A	220_I	0.742	0.96
273_V	276_M	0.741	0.96
54_D	189_A	0.739	0.96
431_G	435_L	0.738	0.96
250_N	253_W	0.736	0.96
81_V	87_A	0.732	0.96
258_L	393_G	0.732	0.96
219_F	406_L	0.723	0.95
224_M	228_M	0.722	0.95
312_T	339_A	0.721	0.95
402_I	405_P	0.721	0.95
319_L	322_I	0.720	0.95
183_A	222_V	0.720	0.95
168_L	173_A	0.720	0.95
54_D	58_A	0.719	0.95
208_F	213_I	0.719	0.95
203_E	348_F	0.719	0.95
84_L	88_V	0.718	0.95
238_L	241_V	0.715	0.95
356_I	444_L	0.713	0.95
323_A	390_A	0.712	0.95
39_A	54_D	0.712	0.95
192_A	357_F	0.711	0.95
61_Q	65_M	0.711	0.95
82_A	89_L	0.710	0.95
94_Y	296_G	0.710	0.95
197_I	219_F	0.708	0.95
44_T	224_M	0.707	0.95
90_A	299_G	0.706	0.95
39_A	220_I	0.700	0.94
33_L	37_F	0.699	0.94
319_L	366_V	0.699	0.94
196_G	199_F	0.699	0.94
392_A	396_A	0.699	0.94
444_L	448_I	0.698	0.94
174_R	178_L	0.697	0.94
300_G	304_L	0.697	0.94
57_V	139_L	0.695	0.94
316_G	340_R	0.695	0.94
311_A	336_I	0.692	0.94
114_G	119_Q	0.692	0.94
90_A	295_G	0.692	0.94
353_P	356_I	0.691	0.94
114_G	117_E	0.690	0.94
266_G	399_A	0.690	0.94
217_A	349_S	0.688	0.94
293_L	296_G	0.687	0.94
277_Q	353_P	0.686	0.94
195_A	404_A	0.686	0.94
265_F	268_I	0.685	0.94
171_D	175_H	0.683	0.94
78_L	88_V	0.682	0.93
255_Y	258_L	0.681	0.93
295_G	298_I	0.675	0.93
263_G	400_A	0.675	0.93
122_V	164_D	0.675	0.93
362_A	365_T	0.673	0.93
131_K	150_P	0.673	0.93
99_K	102_P	0.672	0.93
115_A	160_R	0.670	0.93
87_A	300_G	0.669	0.93
280_L	294_M	0.668	0.93
239_I	323_A	0.666	0.93
430_L	434_L	0.665	0.93
266_G	397_L	0.665	0.93
195_A	356_I	0.664	0.93
90_A	269_F	0.663	0.93
83_F	304_L	0.662	0.92
294_M	302_C	0.662	0.92
144_V	347_C	0.662	0.92
175_H	178_L	0.661	0.92
375_A	379_F	0.661	0.92
412_V	421_L	0.660	0.92
112_I	115_A	0.659	0.92
31_T	34_A	0.657	0.92
92_F	95_F	0.657	0.92
97_V	102_P	0.656	0.92
78_L	81_V	0.655	0.92
66_G	374_V	0.653	0.92
106_G	110_P	0.652	0.92
178_L	211_T	0.644	0.91
335_F	338_V	0.643	0.91
410_I	413_L	0.642	0.91
246_D	249_L	0.639	0.91
111_E	114_G	0.639	0.91
220_I	225_S	0.639	0.91
125_W	164_D	0.637	0.91
131_K	149_G	0.636	0.91
397_L	401_S	0.636	0.91
131_K	134_G	0.636	0.91
163_L	181_G	0.633	0.91
104_A	131_K	0.632	0.91
269_F	445_Y	0.632	0.91
227_I	231_I	0.630	0.91
151_T	407_T	0.629	0.90
364_G	393_G	0.628	0.90
138_T	353_P	0.626	0.90
36_L	43_G	0.624	0.90
60_L	67_A	0.623	0.90
139_L	150_P	0.622	0.90
187_A	229_Y	0.622	0.90
92_F	96_L	0.622	0.90
262_F	401_S	0.620	0.90
442_K	447_A	0.619	0.90
311_A	322_I	0.617	0.90
222_V	225_S	0.616	0.90
195_A	410_I	0.616	0.90
115_A	120_R	0.615	0.89
383_H	389_F	0.615	0.89
269_F	363_L	0.615	0.89
316_G	361_L	0.613	0.89
344_T	363_L	0.613	0.89
63_Q	66_G	0.612	0.89
144_V	343_T	0.612	0.89
266_G	270_N	0.610	0.89
185_G	263_G	0.609	0.89
149_G	414_E	0.606	0.89
327_N	331_G	0.606	0.89
87_A	303_G	0.603	0.89
197_I	201_I	0.602	0.88
226_T	229_Y	0.600	0.88
281_H	285_G	0.600	0.88
96_L	130_V	0.599	0.88
330_M	373_M	0.595	0.88
149_G	353_P	0.595	0.88
253_W	256_L	0.594	0.88
330_M	374_V	0.591	0.88
51_V	233_N	0.591	0.88
186_L	421_L	0.587	0.87
218_V	227_I	0.586	0.87
111_E	116_L	0.586	0.87
255_Y	259_G	0.585	0.87
266_G	345_L	0.585	0.87
262_F	428_T	0.583	0.87
338_V	374_V	0.583	0.87
100_Y	130_V	0.582	0.87
147_R	153_Q	0.581	0.87
100_Y	103_E	0.580	0.87
78_L	82_A	0.580	0.87
152_V	357_F	0.580	0.87
385_E	390_A	0.579	0.86
324_T	387_G	0.579	0.86
235_E	238_L	0.577	0.86
88_V	92_F	0.576	0.86
340_R	351_G	0.576	0.86
187_A	419_Y	0.574	0.86
96_L	307_F	0.573	0.86
309_A	343_T	0.572	0.86
53_F	147_R	0.572	0.86
99_K	104_A	0.570	0.86
369_T	372_G	0.568	0.85
53_F	132_F	0.567	0.85
38_M	166_F	0.565	0.85
51_V	188_A	0.565	0.85
139_L	356_I	0.565	0.85
104_A	127_V	0.563	0.85
86_S	94_Y	0.563	0.85
179_A	200_I	0.562	0.85
336_I	362_A	0.561	0.85
390_A	393_G	0.560	0.85
127_V	131_K	0.559	0.84
436_A	441_G	0.557	0.84
370_A	373_M	0.556	0.84
274_L	278_D	0.556	0.84
90_A	96_L	0.555	0.84
42_V	159_G	0.554	0.84
135_G	402_I	0.553	0.84
196_G	263_G	0.553	0.84
165_I	374_V	0.551	0.84
54_D	147_R	0.551	0.84
203_E	404_A	0.551	0.84
139_L	151_T	0.551	0.84
162_V	166_F	0.550	0.84
115_A	119_Q	0.550	0.84
187_A	225_S	0.550	0.84
153_Q	353_P	0.549	0.83
435_L	439_T	0.549	0.83
93_G	137_G	0.549	0.83
113_E	446_S	0.548	0.83
94_Y	100_Y	0.547	0.83
189_A	348_F	0.547	0.83
326_G	329_S	0.547	0.83
103_E	124_W	0.546	0.83
173_A	176_T	0.546	0.83
124_W	127_V	0.545	0.83
182_A	186_L	0.545	0.83
402_I	411_L	0.545	0.83
40_A	228_M	0.545	0.83
302_C	306_G	0.544	0.83
78_L	430_L	0.544	0.83
85_C	93_G	0.542	0.83
35_I	177_L	0.542	0.83
261_I	285_G	0.542	0.83
53_F	149_G	0.540	0.82
92_F	377_E	0.540	0.82
145_L	358_A	0.539	0.82
247_A	251_T	0.538	0.82
344_T	347_C	0.537	0.82
110_P	117_E	0.535	0.82
77_L	81_V	0.535	0.82
98_R	101_A	0.534	0.82
68_L	403_R	0.533	0.82
96_L	99_K	0.533	0.82
139_L	408_G	0.532	0.81
199_F	445_Y	0.531	0.81
338_V	342_I	0.530	0.81
185_G	404_A	0.530	0.81
372_G	400_A	0.530	0.81
217_A	224_M	0.529	0.81
185_G	259_G	0.528	0.81
219_F	223_I	0.528	0.81
90_A	97_V	0.527	0.81
180_T	218_V	0.527	0.81
55_K	232_F	0.526	0.81
38_M	162_V	0.526	0.81
93_G	104_A	0.525	0.81
383_H	386_A	0.523	0.80
342_I	374_V	0.523	0.80
104_A	107_S	0.523	0.80
377_E	380_P	0.522	0.80
332_M	335_F	0.521	0.80
306_G	310_P	0.521	0.80
224_M	231_I	0.520	0.80
419_Y	422_I	0.519	0.80
110_P	152_V	0.519	0.80
191_N	234_H	0.518	0.80
47_G	228_M	0.517	0.80
229_Y	411_L	0.517	0.80
404_A	407_T	0.516	0.80
361_L	397_L	0.515	0.79
113_E	117_E	0.515	0.79
161_M	164_D	0.515	0.79
361_L	398_L	0.514	0.79
258_L	389_F	0.514	0.79
292_V	295_G	0.513	0.79
328_F	333_L	0.513	0.79
374_V	377_E	0.512	0.79
43_G	54_D	0.512	0.79
191_N	207_Q	0.511	0.79
46_V	54_D	0.511	0.79
108_G	116_L	0.510	0.79
154_I	425_M	0.509	0.79
221_G	224_M	0.509	0.79
265_F	374_V	0.509	0.79
46_V	357_F	0.509	0.79
149_G	190_F	0.509	0.79
186_L	357_F	0.506	0.78
87_A	91_M	0.506	0.78
189_A	263_G	0.506	0.78
318_N	322_I	0.505	0.78
75_Y	264_I	0.504	0.78
236_V	239_I	0.504	0.78
45_L	165_I	0.504	0.78
280_L	283_V	0.504	0.78
50_A	54_D	0.503	0.78
168_L	174_R	0.503	0.78
373_M	386_A	0.500	0.77

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3nd0A	2	0.8985	100	0.182	Contact Map
4eneA	2	0.9387	100	0.191	Contact Map
3orgA	2	0.8732	100	0.253	Contact Map
1jcnA	6	0.2051	98.9	0.885	Contact Map
4j05A	3	0.8224	83.2	0.954	Contact Map
3usbA	4	0.1987	81	0.955	Contact Map
2cfqA	1	0.4693	52.5	0.963	Contact Map
1pw4A	1	0.852	44.4	0.965	Contact Map
4zw9A	1	0.8499	42.1	0.965	Contact Map
2kogA	1	0.1142	22.7	0.97	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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