GREMLIN Database
YAGB - Putative uncharacterized protein YagB
UniProt: P37008 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG12339
Length: 116 (102)
Sequences: 154 (50)
Seq/√Len: 5.0

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
62_L76_A4.6040.95
87_T106_R3.2330.76
32_F39_F2.2210.47
64_L82_Y2.1520.44
8_T18_C2.0990.43
65_M72_N2.0350.41
48_T57_H2.0280.40
53_E57_H1.9960.39
58_F76_A1.9630.38
24_V31_H1.9390.38
32_F96_H1.9020.37
12_K15_I1.8880.36
27_G43_F1.8790.36
24_V73_P1.7030.31
19_F105_N1.6730.30
39_F106_R1.6200.29
57_H86_L1.6180.28
32_F38_G1.6130.28
53_E59_V1.5960.28
31_H73_P1.5750.27
25_Q66_L1.4980.25
60_A76_A1.4230.24
31_H66_L1.4100.23
12_K18_C1.4070.23
81_L105_N1.3990.23
93_L102_A1.3550.22
53_E86_L1.3530.22
10_G17_P1.3310.22
58_F84_N1.3250.21
54_A83_R1.3170.21
57_H76_A1.2460.20
67_L79_V1.2420.20
39_F64_L1.2220.19
25_Q44_S1.2010.19
52_D96_H1.2000.19
15_I78_C1.1830.18
92_T99_V1.1820.18
32_F48_T1.1680.18
58_F62_L1.1100.17
11_L98_Y1.1030.17
7_Q101_I1.1020.17
26_E31_H1.0940.17
83_R93_L1.0910.17
89_E93_L1.0870.17
28_H32_F1.0730.16
13_R78_C1.0700.16
74_R80_T1.0570.16
13_R39_F1.0560.16
47_Q72_N1.0490.16
7_Q27_G1.0480.16
19_F60_A1.0370.16
32_F72_N1.0220.16
51_L94_G1.0220.16
13_R46_V1.0180.15
29_R106_R1.0140.15
37_A99_V1.0140.15
6_T76_A0.9840.15
96_H107_H0.9780.15
33_L41_G0.9710.15
59_V86_L0.9620.15
43_F61_H0.9580.14
12_K42_S0.9580.14
59_V80_T0.9500.14
24_V66_L0.9360.14
44_S102_A0.9300.14
39_F46_V0.9180.14
18_C49_L0.9130.14
47_Q105_N0.9010.14
40_T103_I0.8870.13
64_L77_H0.8670.13
17_P41_G0.8660.13
50_Q86_L0.8570.13
25_Q73_P0.8550.13
56_P70_E0.8490.13
53_E61_H0.8490.13
80_T87_T0.8430.13
32_F46_V0.8410.13
17_P33_L0.8280.13
78_C93_L0.8240.12
30_L41_G0.8230.12
39_F48_T0.8230.12
43_F73_P0.8200.12
47_Q83_R0.8200.12
51_L71_L0.8050.12
10_G41_G0.8010.12
81_L103_I0.7850.12
13_R20_G0.7830.12
30_L33_L0.7770.12
21_A91_D0.7720.12
49_L81_L0.7690.12
19_F86_L0.7690.12
72_N82_Y0.7660.12
37_A52_D0.7630.12
10_G33_L0.7600.12
75_Y82_Y0.7580.12
40_T99_V0.7560.12
6_T38_G0.7520.11
65_M70_E0.7510.11
66_L71_L0.7470.11
73_P99_V0.7310.11
50_Q58_F0.7280.11
47_Q84_N0.7250.11
41_G104_L0.7250.11
25_Q31_H0.7180.11
81_L93_L0.7120.11
66_L99_V0.7100.11
18_C86_L0.7040.11
78_C103_I0.6890.11
61_H70_E0.6830.11
33_L104_L0.6820.11
13_R102_A0.6760.11
29_R105_N0.6670.10
10_G30_L0.6620.10
17_P30_L0.6610.10
66_L73_P0.6560.10
39_F59_V0.6550.10
27_G68_S0.6550.10
21_A37_A0.6530.10
7_Q39_F0.6520.10
58_F93_L0.6440.10
40_T105_N0.6320.10
7_Q44_S0.6320.10
37_A56_P0.6300.10
75_Y83_R0.6200.10
83_R86_L0.5960.10
47_Q61_H0.5900.10
61_H96_H0.5820.09
31_H99_V0.5810.09
50_Q53_E0.5810.09
18_C65_M0.5740.09
93_L101_I0.5720.09
29_R47_Q0.5660.09
49_L84_N0.5650.09
17_P104_L0.5640.09
49_L52_D0.5620.09
47_Q58_F0.5610.09
20_G74_R0.5550.09
26_E98_Y0.5540.09
39_F82_Y0.5530.09
67_L75_Y0.5340.09
12_K78_C0.5340.09
24_V48_T0.5330.09
48_T86_L0.5320.09
28_H54_A0.5310.09
47_Q59_V0.5310.09
26_E71_L0.5310.09
39_F74_R0.5290.09
73_P86_L0.5270.09
68_S86_L0.5240.09
42_S68_S0.5180.09
64_L84_N0.5170.09
58_F83_R0.5070.09
76_A90_A0.5000.09
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2inwA 1 0.9397 100 0.112 Contact Map
2ea9A 1 0.8879 100 0.115 Contact Map
1dquA 4 0.9138 21.1 0.954 Contact Map
1d3yA 2 0.6207 12.1 0.959 Contact Map
4jm1A 1 0.3621 9.7 0.961 Contact Map
3h2tA 2 0.319 8.9 0.961 Contact Map
3hvmA 1 0.6897 8.2 0.962 Contact Map
3aqoA 1 0.5862 7.9 0.962 Contact Map
4p1eA 1 0.4828 7.5 0.963 Contact Map
1xv2A 2 0.5776 6.5 0.964 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0063 seconds.