GREMLIN Database
YBFG - Putative uncharacterized protein YbfG
UniProt: P37003 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG11777
Length: 216 (208)
Sequences: 166 (126)
Seq/√Len: 8.8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
67_D162_R4.7370.99
71_L149_A3.9250.98
112_A135_W3.2940.94
119_G126_Y3.2410.93
102_I125_V2.8580.87
180_T197_V2.7150.84
135_W148_W2.6940.84
85_P89_T2.6850.84
190_E193_R2.5050.79
140_V184_F2.5010.79
50_T59_Y2.4480.77
42_A84_D2.4420.77
162_R166_W2.3720.75
74_A104_D2.3020.73
83_R104_D2.2780.72
118_L145_F2.2200.70
46_L58_V2.1910.69
64_L73_I2.1200.66
76_S83_R2.0010.61
163_W166_W1.9880.61
76_S175_A1.9530.60
113_L154_L1.9330.59
160_N181_F1.9140.58
48_V52_S1.8710.56
131_D183_P1.8680.56
70_X163_W1.8430.55
29_T150_L1.8230.54
129_A136_E1.8210.54
189_S193_R1.7790.52
64_L111_F1.7350.50
30_E128_F1.6760.48
106_V178_A1.6120.45
113_L128_F1.6110.45
66_I184_F1.6090.45
2_R41_T1.6000.44
101_P187_V1.5490.42
100_L138_L1.5310.42
71_L150_L1.5200.41
51_K141_G1.5010.40
67_D70_X1.4720.39
133_L183_P1.4690.39
169_D195_R1.4540.38
165_Q196_K1.4380.38
170_V205_E1.4330.38
61_S188_Q1.4280.37
15_W27_N1.4010.36
22_L146_L1.4010.36
15_W178_A1.3890.36
7_L43_L1.3890.36
2_R144_E1.3810.36
131_D184_F1.3740.35
61_S80_R1.3700.35
174_S177_E1.3700.35
152_G163_W1.3540.34
57_L79_P1.3530.34
12_D17_I1.3440.34
61_S142_Y1.3420.34
116_G145_F1.3270.33
187_V191_E1.3150.33
49_T52_S1.3130.33
15_W31_L1.3050.33
43_L47_Q1.3030.33
178_A203_L1.2800.32
9_N68_N1.2790.32
52_S111_F1.2780.32
129_A143_S1.2530.31
102_I196_K1.2310.30
42_A54_M1.2190.29
180_T198_I1.2110.29
14_A18_I1.1940.29
35_N113_L1.1920.28
16_P125_V1.1880.28
4_M165_Q1.1870.28
42_A145_F1.1710.28
10_T13_S1.1620.27
38_L57_L1.1590.27
106_V152_G1.1490.27
104_D145_F1.1480.27
81_L111_F1.1420.27
163_W195_R1.1400.27
31_L167_R1.1340.26
120_E142_Y1.1270.26
181_F185_L1.1130.26
23_K174_S1.1110.26
14_A139_E1.1100.26
15_W152_G1.1090.26
18_I102_I1.1070.26
203_L207_Q1.1010.25
35_N102_I1.0970.25
102_I106_V1.0910.25
32_L195_R1.0910.25
135_W161_V1.0900.25
27_N31_L1.0750.25
71_L141_G1.0750.25
4_M171_I1.0540.24
18_I205_E1.0520.24
72_R123_G1.0460.24
102_I194_T1.0440.24
101_P104_D1.0400.23
93_E170_V1.0260.23
132_T135_W1.0200.23
104_D190_E1.0090.23
37_D198_I1.0010.22
50_T119_G0.9990.22
49_T176_T0.9990.22
112_A152_G0.9980.22
73_I149_A0.9960.22
110_I204_W0.9870.22
70_X162_R0.9820.22
24_D64_L0.9810.22
169_D178_A0.9810.22
13_S51_K0.9800.22
86_V112_A0.9740.21
27_N153_D0.9720.21
70_X166_W0.9630.21
15_W140_V0.9620.21
181_F206_M0.9610.21
9_N29_T0.9480.21
118_L168_E0.9460.21
198_I202_E0.9400.21
99_A204_W0.9400.21
38_L76_S0.9370.20
115_G123_G0.9350.20
22_L45_Q0.9220.20
57_L171_I0.9190.20
4_M112_A0.9180.20
8_V33_P0.9040.20
2_R49_T0.9030.20
40_E84_D0.9010.19
61_S65_L0.8920.19
2_R6_Q0.8910.19
60_G64_L0.8880.19
71_L135_W0.8860.19
30_E65_L0.8770.19
110_I118_L0.8760.19
68_N167_R0.8740.19
148_W185_L0.8730.19
176_T200_L0.8700.19
144_E176_T0.8680.19
42_A53_P0.8640.18
32_L62_G0.8590.18
60_G117_D0.8590.18
12_D51_K0.8550.18
111_F129_A0.8540.18
112_A148_W0.8540.18
89_T116_G0.8540.18
62_G77_G0.8510.18
23_K107_A0.8470.18
173_L198_I0.8410.18
76_S104_D0.8400.18
164_Q191_E0.8350.18
5_N197_V0.8340.18
92_P201_T0.8290.18
88_W110_I0.8240.17
153_D156_T0.8240.17
22_L187_V0.8230.17
46_L160_N0.8160.17
87_S147_Q0.8160.17
154_L173_L0.8120.17
19_Q26_T0.8110.17
120_E129_A0.8080.17
135_W152_G0.8080.17
24_D194_T0.8060.17
30_E76_S0.8060.17
55_G70_X0.8050.17
58_V180_T0.8020.17
102_I153_D0.8000.17
74_A190_E0.7990.17
152_G203_L0.7980.17
18_I139_E0.7970.17
3_E113_L0.7940.17
13_S209_Q0.7860.17
10_T31_L0.7860.17
18_I178_A0.7830.16
71_L138_L0.7690.16
67_D166_W0.7680.16
125_V168_E0.7640.16
111_F148_W0.7610.16
51_K115_G0.7570.16
3_E167_R0.7560.16
151_S176_T0.7520.16
115_G169_D0.7520.16
60_G198_I0.7460.16
25_A83_R0.7420.16
128_F198_I0.7410.16
83_R101_P0.7410.16
64_L197_V0.7400.15
145_F149_A0.7400.15
140_V152_G0.7380.15
22_L159_E0.7360.15
145_F184_F0.7330.15
112_A149_A0.7320.15
52_S169_D0.7290.15
139_E188_Q0.7260.15
56_A202_E0.7250.15
160_N180_T0.7200.15
83_R175_A0.7170.15
82_P125_V0.7140.15
57_L142_Y0.7090.15
45_Q98_R0.7080.15
113_L138_L0.7050.15
88_W103_A0.7050.15
156_T172_K0.7010.15
17_I48_V0.7000.15
106_V154_L0.6970.15
136_E158_Y0.6960.15
66_I103_A0.6950.15
131_D136_E0.6890.14
31_L91_R0.6880.14
13_S179_F0.6860.14
21_W53_P0.6850.14
22_L86_V0.6790.14
75_G186_W0.6790.14
84_D87_S0.6790.14
42_A121_D0.6780.14
132_T190_E0.6750.14
146_L176_T0.6720.14
4_M120_E0.6690.14
84_D110_I0.6680.14
59_Y76_S0.6680.14
22_L29_T0.6670.14
21_W96_G0.6640.14
72_R138_L0.6640.14
25_A184_F0.6620.14
35_N175_A0.6570.14
130_P182_Y0.6570.14
7_L47_Q0.6530.14
17_I21_W0.6470.14
124_C137_S0.6470.14
131_D182_Y0.6410.13
13_S72_R0.6390.13
183_P186_W0.6380.13
178_A200_L0.6370.13
13_S182_Y0.6350.13
54_M58_V0.6300.13
65_L175_A0.6290.13
25_A181_F0.6260.13
16_P82_P0.6250.13
52_S163_W0.6230.13
44_Y71_L0.6180.13
18_I39_A0.6150.13
57_L146_L0.6140.13
72_R76_S0.6110.13
25_A157_F0.6080.13
91_R117_D0.6060.13
17_I128_F0.6060.13
200_L207_Q0.6030.13
50_T74_A0.5970.13
121_D126_Y0.5950.12
68_N85_P0.5930.12
55_G135_W0.5930.12
99_A118_L0.5880.12
79_P165_Q0.5880.12
33_P103_A0.5860.12
19_Q149_A0.5840.12
43_L55_G0.5810.12
51_K194_T0.5810.12
4_M129_A0.5790.12
13_S20_N0.5770.12
172_K191_E0.5760.12
166_W195_R0.5740.12
132_T148_W0.5670.12
141_G144_E0.5670.12
67_D163_W0.5630.12
88_W204_W0.5610.12
57_L153_D0.5600.12
91_R98_R0.5590.12
42_A138_L0.5580.12
96_G193_R0.5580.12
145_F148_W0.5570.12
4_M44_Y0.5540.12
63_G85_P0.5540.12
165_Q169_D0.5530.12
39_A53_P0.5520.12
2_R5_N0.5510.12
60_G153_D0.5490.12
64_L165_Q0.5480.12
49_T143_S0.5440.12
163_W169_D0.5430.12
106_V173_L0.5390.11
14_A53_P0.5380.11
35_N193_R0.5360.11
173_L189_S0.5350.11
82_P120_E0.5300.11
124_C139_E0.5300.11
162_R170_V0.5280.11
66_I116_G0.5250.11
151_S175_A0.5220.11
11_E79_P0.5210.11
42_A58_V0.5200.11
25_A146_L0.5190.11
91_R101_P0.5170.11
125_V153_D0.5160.11
156_T209_Q0.5150.11
74_A88_W0.5150.11
111_F125_V0.5140.11
5_N120_E0.5140.11
189_S204_W0.5130.11
22_L26_T0.5120.11
11_E38_L0.5110.11
88_W107_A0.5110.11
76_S181_F0.5110.11
129_A133_L0.5100.11
171_I201_T0.5090.11
28_H197_V0.5080.11
161_V189_S0.5060.11
101_P178_A0.5050.11
83_R181_F0.5040.11
111_F176_T0.5020.11
18_I62_G0.5020.11
66_I84_D0.5000.11
24_D165_Q0.5000.11
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2prvA 2 0.6759 89.5 0.946 Contact Map
2icgA 1 0.6481 84.4 0.95 Contact Map
2pagA 1 0.5926 63.9 0.958 Contact Map
3d5pA 2 0.5741 50.7 0.961 Contact Map
2wcuA 2 0.3009 13.9 0.971 Contact Map
2uuuA 2 0.3148 11.2 0.972 Contact Map
3e7nA 6 0.287 7.3 0.974 Contact Map
3lk5A 2 0.2269 6.3 0.975 Contact Map
1v2zA 2 0.2963 5.9 0.975 Contact Map
2wcvA 7 0.2963 5.5 0.975 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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