RLMN - ECOLI - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

RLMN - Dual-specificity RNA methyltransferase RlmN

UniProt:	P36979	Sequences: MSEQLVTPENVTTKDGKINLLDLNRQQMREFFKDLGEKPFRADQVMKWMYHYCCDNFDEMTDINKVLRGKLKEVAEIRAPEVVEEQRSSDGTIKWAIAVGDQRVETVYIPEDDRATLCVSSQVGCALECKFCSTAQQGFNRNLRVSEIIGQVWRAAKIVGAAKVTGQRPITNVVMMGMGEPLLNLNNVVPAMEIMLDDFGFGLSKRRVTLSTSGVVPALDKLGDMIDVALAISLHAPNDEIRDEIVPINKKYNIETFLAAVRRYLEKSNANQGRVTIEYVMLDHVNDGTEHAHQLAELLKDTPCKINLIPWNPFPGAPYGRSSNSRIDRFSKVLMSYGFTTIVRKTRGDDIDAACGQLAGDVIDRTKRTLRKRMQGEAIDIKAV	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG12401
Length:	384 (337)
Sequences:	3178 (1726)
Seq/√Len:	94.0

ECOLI - RLMN
BACSU - RLMN

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
238_N	294_Q	4.149	1.00
220_D	263_R	3.635	1.00
218_A	221_K	3.465	1.00
185_L	225_M	3.456	1.00
81_E	98_A	3.062	1.00
58_D	72_K	3.047	1.00
239_D	255_E	3.026	1.00
32_F	45_V	2.957	1.00
243_D	249_N	2.907	1.00
27_Q	190_P	2.907	1.00
95_W	158_I	2.840	1.00
130_K	319_Y	2.621	1.00
224_D	267_K	2.568	1.00
296_A	337_Y	2.567	1.00
175_M	191_A	2.493	1.00
37_E	70_K	2.407	1.00
283_D	320_G	2.405	1.00
126_A	183_L	2.403	1.00
258_L	298_L	2.391	1.00
306_I	339_F	2.386	1.00
56_N	59_E	2.370	1.00
224_D	263_R	2.352	1.00
29_R	39_P	2.319	1.00
289_T	333_V	2.290	1.00
262_R	302_T	2.259	1.00
288_G	291_H	2.247	1.00
332_K	336_S	2.233	1.00
30_E	34_D	2.216	1.00
188_V	210_L	2.210	1.00
119_V	148_I	2.157	1.00
193_E	225_M	2.074	1.00
241_I	291_H	2.067	1.00
281_M	322_S	2.054	1.00
69_G	73_E	2.048	1.00
192_M	210_L	2.023	1.00
31_F	75_A	1.960	1.00
293_H	333_V	1.953	1.00
86_Q	352_D	1.942	1.00
47_K	62_D	1.917	1.00
237_P	291_H	1.914	1.00
239_D	249_N	1.907	1.00
88_S	350_D	1.873	1.00
221_K	225_M	1.852	1.00
126_A	139_F	1.849	1.00
289_T	326_R	1.836	1.00
261_V	275_V	1.809	1.00
173_V	195_M	1.798	1.00
33_K	39_P	1.786	1.00
85_E	158_I	1.766	1.00
217_P	252_Y	1.763	1.00
31_F	35_L	1.748	1.00
237_P	294_Q	1.745	1.00
48_W	62_D	1.740	1.00
127_L	213_S	1.735	1.00
283_D	323_S	1.722	1.00
83_V	98_A	1.720	1.00
117_L	155_A	1.709	1.00
238_N	241_I	1.700	1.00
48_W	60_M	1.695	1.00
182_L	222_L	1.694	1.00
47_K	51_H	1.629	1.00
55_D	157_K	1.585	1.00
29_R	43_D	1.577	1.00
175_M	188_V	1.553	1.00
24_N	27_Q	1.553	1.00
205_K	227_D	1.530	1.00
175_M	210_L	1.523	1.00
25_R	197_D	1.509	1.00
243_D	250_K	1.500	1.00
85_E	93_I	1.496	1.00
32_F	67_L	1.495	1.00
43_D	199_F	1.468	1.00
47_K	52_Y	1.461	1.00
183_L	215_V	1.459	1.00
70_K	74_V	1.447	1.00
95_W	155_A	1.437	1.00
239_D	243_D	1.430	0.99
21_L	150_G	1.419	0.99
232_I	257_F	1.411	0.99
259_A	263_R	1.396	0.99
220_D	259_A	1.390	0.99
20_L	57_F	1.386	0.99
352_D	361_D	1.373	0.99
277_I	304_C	1.367	0.99
121_S	175_M	1.359	0.99
98_A	103_R	1.348	0.99
293_H	337_Y	1.336	0.99
121_S	188_V	1.332	0.99
80_P	150_G	1.324	0.99
289_T	329_R	1.323	0.99
204_S	207_R	1.317	0.99
26_Q	29_R	1.316	0.99
328_D	331_S	1.312	0.99
291_H	294_Q	1.306	0.99
25_R	29_R	1.302	0.99
19_N	22_D	1.293	0.99
331_S	335_M	1.293	0.99
253_N	256_T	1.282	0.99
323_S	326_R	1.274	0.99
97_I	106_T	1.271	0.99
137_Q	360_G	1.258	0.99
63_I	68_R	1.249	0.99
145_V	187_N	1.236	0.99
283_D	326_R	1.234	0.98
108_Y	115_A	1.231	0.98
182_L	210_L	1.229	0.98
262_R	301_D	1.224	0.98
238_N	291_H	1.222	0.98
67_L	70_K	1.220	0.98
331_S	341_T	1.219	0.98
97_I	154_R	1.218	0.98
324_N	328_D	1.210	0.98
41_R	44_Q	1.201	0.98
35_L	70_K	1.199	0.98
152_V	195_M	1.195	0.98
69_G	72_K	1.174	0.98
80_P	97_I	1.173	0.98
333_V	337_Y	1.167	0.98
65_K	69_G	1.167	0.98
66_V	69_G	1.166	0.98
281_M	327_I	1.158	0.98
99_V	104_V	1.156	0.98
237_P	241_I	1.154	0.98
54_C	59_E	1.151	0.98
134_T	178_M	1.149	0.98
236_A	241_I	1.148	0.98
37_E	67_L	1.145	0.98
220_D	224_D	1.143	0.98
196_L	205_K	1.139	0.97
23_L	31_F	1.136	0.97
254_I	298_L	1.136	0.97
215_V	218_A	1.132	0.97
108_Y	155_A	1.124	0.97
24_N	190_P	1.123	0.97
79_A	150_G	1.123	0.97
277_I	302_T	1.122	0.97
32_F	42_A	1.122	0.97
37_E	41_R	1.117	0.97
216_V	260_A	1.115	0.97
196_L	208_V	1.112	0.97
87_R	93_I	1.112	0.97
18_I	75_A	1.110	0.97
277_I	299_L	1.107	0.97
239_D	253_N	1.106	0.97
196_L	227_D	1.103	0.97
102_Q	140_N	1.102	0.97
193_E	226_I	1.102	0.97
223_G	263_R	1.102	0.97
50_Y	201_F	1.100	0.97
189_V	225_M	1.097	0.97
106_T	155_A	1.095	0.97
299_L	306_I	1.094	0.97
185_L	189_V	1.066	0.96
99_V	123_V	1.064	0.96
40_F	44_Q	1.060	0.96
243_D	246_V	1.060	0.96
57_F	76_E	1.059	0.96
258_L	302_T	1.053	0.96
284_H	326_R	1.051	0.96
185_L	221_K	1.050	0.96
117_L	170_I	1.047	0.96
53_C	156_A	1.045	0.96
25_R	43_D	1.033	0.95
45_V	63_I	1.031	0.95
196_L	204_S	1.030	0.95
82_V	85_E	1.025	0.95
20_L	75_A	1.025	0.95
289_T	293_H	1.025	0.95
24_N	193_E	1.025	0.95
145_V	190_P	1.022	0.95
25_R	42_A	1.020	0.95
240_E	244_E	1.019	0.95
327_I	343_V	1.017	0.95
328_D	343_V	1.016	0.95
321_R	349_D	1.008	0.95
101_D	141_R	1.006	0.95
148_I	191_A	1.006	0.95
263_R	267_K	1.005	0.95
26_Q	193_E	1.003	0.95
292_A	333_V	0.997	0.94
29_R	33_K	0.990	0.94
229_A	273_G	0.989	0.94
256_T	259_A	0.986	0.94
209_T	231_A	0.984	0.94
43_D	62_D	0.977	0.94
139_F	183_L	0.976	0.94
61_T	68_R	0.973	0.94
249_N	253_N	0.970	0.94
116_T	172_N	0.970	0.94
139_F	142_N	0.968	0.94
37_E	66_V	0.965	0.93
156_A	201_F	0.962	0.93
299_L	339_F	0.961	0.93
265_L	303_P	0.960	0.93
31_F	34_D	0.957	0.93
61_T	64_N	0.956	0.93
258_L	261_V	0.953	0.93
255_E	298_L	0.952	0.93
57_F	60_M	0.950	0.93
136_Q	316_G	0.949	0.93
258_L	262_R	0.943	0.93
175_M	192_M	0.937	0.92
282_L	285_V	0.936	0.92
22_D	146_S	0.933	0.92
334_L	341_T	0.932	0.92
292_A	330_F	0.932	0.92
329_R	332_K	0.930	0.92
149_I	194_I	0.925	0.92
222_L	228_V	0.923	0.92
188_V	192_M	0.922	0.92
296_A	339_F	0.919	0.92
66_V	70_K	0.912	0.91
325_S	329_R	0.910	0.91
313_P	349_D	0.908	0.91
127_L	183_L	0.906	0.91
83_V	103_R	0.904	0.91
33_K	38_K	0.901	0.91
57_F	77_I	0.899	0.91
133_S	352_D	0.897	0.91
280_V	311_W	0.892	0.90
43_D	47_K	0.892	0.90
219_L	232_I	0.889	0.90
56_N	72_K	0.888	0.90
241_I	294_Q	0.888	0.90
114_R	347_R	0.888	0.90
30_E	33_K	0.880	0.90
175_M	195_M	0.874	0.90
80_P	106_T	0.873	0.90
215_V	248_I	0.873	0.90
232_I	261_V	0.872	0.89
84_E	362_V	0.870	0.89
287_D	322_S	0.867	0.89
93_I	158_I	0.866	0.89
97_I	155_A	0.866	0.89
18_I	23_L	0.864	0.89
106_T	117_L	0.862	0.89
189_V	222_L	0.855	0.89
48_W	52_Y	0.855	0.89
80_P	154_R	0.847	0.88
186_N	221_K	0.847	0.88
89_S	350_D	0.846	0.88
137_Q	359_A	0.843	0.88
332_K	335_M	0.842	0.88
254_I	258_L	0.836	0.87
282_L	311_W	0.836	0.87
133_S	314_F	0.833	0.87
113_D	172_N	0.826	0.87
254_I	259_A	0.823	0.87
311_W	317_A	0.822	0.87
322_S	327_I	0.822	0.87
52_Y	62_D	0.821	0.86
21_L	50_Y	0.816	0.86
79_A	157_K	0.816	0.86
153_W	201_F	0.814	0.86
213_S	246_V	0.814	0.86
294_Q	297_E	0.813	0.86
32_F	35_L	0.804	0.85
198_D	202_G	0.804	0.85
96_A	359_A	0.797	0.85
26_Q	30_E	0.796	0.85
241_I	244_E	0.796	0.85
127_L	248_I	0.795	0.85
261_V	277_I	0.792	0.84
113_D	134_T	0.790	0.84
110_P	168_R	0.790	0.84
195_M	201_F	0.784	0.84
173_V	208_V	0.777	0.83
54_C	60_M	0.776	0.83
57_F	71_L	0.776	0.83
141_R	147_E	0.772	0.83
322_S	326_R	0.771	0.83
185_L	193_E	0.770	0.83
50_Y	153_W	0.769	0.83
346_T	349_D	0.767	0.82
220_D	260_A	0.766	0.82
108_Y	159_V	0.765	0.82
154_R	157_K	0.762	0.82
243_D	253_N	0.762	0.82
80_P	99_V	0.760	0.82
110_P	115_A	0.760	0.82
313_P	320_G	0.759	0.82
48_W	54_C	0.758	0.82
22_D	144_R	0.756	0.82
182_L	218_A	0.751	0.81
85_E	95_W	0.749	0.81
31_F	74_V	0.748	0.81
35_L	74_V	0.748	0.81
49_M	77_I	0.744	0.81
149_I	195_M	0.741	0.80
173_V	203_L	0.738	0.80
156_A	160_G	0.736	0.80
296_A	334_L	0.733	0.80
210_L	228_V	0.733	0.80
63_I	67_L	0.732	0.79
18_I	31_F	0.731	0.79
189_V	193_E	0.730	0.79
149_I	153_W	0.728	0.79
45_V	57_F	0.728	0.79
46_M	194_I	0.728	0.79
310_P	346_T	0.722	0.79
300_K	337_Y	0.722	0.79
38_K	64_N	0.720	0.78
130_K	136_Q	0.719	0.78
38_K	41_R	0.718	0.78
335_M	341_T	0.718	0.78
41_R	64_N	0.715	0.78
134_T	175_M	0.714	0.78
254_I	257_F	0.713	0.78
328_D	332_K	0.713	0.78
86_Q	361_D	0.712	0.78
305_K	342_I	0.712	0.78
326_R	329_R	0.712	0.78
236_A	239_D	0.711	0.77
209_T	276_T	0.709	0.77
57_F	75_A	0.709	0.77
221_K	224_D	0.707	0.77
136_Q	314_F	0.706	0.77
114_R	134_T	0.706	0.77
114_R	172_N	0.705	0.77
137_Q	178_M	0.697	0.76
220_D	256_T	0.696	0.76
46_M	50_Y	0.695	0.76
134_T	137_Q	0.692	0.76
296_A	333_V	0.692	0.76
111_E	114_R	0.689	0.75
235_H	342_I	0.686	0.75
193_E	197_D	0.686	0.75
213_S	248_I	0.685	0.75
39_P	42_A	0.683	0.75
80_P	104_V	0.681	0.74
321_R	327_I	0.680	0.74
189_V	228_V	0.677	0.74
55_D	59_E	0.673	0.74
219_L	260_A	0.673	0.74
126_A	138_G	0.670	0.73
297_E	337_Y	0.668	0.73
27_Q	30_E	0.667	0.73
65_K	68_R	0.665	0.73
265_L	269_N	0.664	0.73
133_S	315_P	0.662	0.72
287_D	326_R	0.659	0.72
196_L	203_L	0.657	0.72
248_I	252_Y	0.656	0.72
325_S	328_D	0.655	0.72
253_N	257_F	0.655	0.72
235_H	246_V	0.650	0.71
136_Q	317_A	0.650	0.71
244_E	285_V	0.647	0.71
156_A	170_I	0.645	0.70
191_A	195_M	0.643	0.70
311_W	314_F	0.643	0.70
37_E	64_N	0.643	0.70
20_L	49_M	0.642	0.70
329_R	333_V	0.641	0.70
290_E	294_Q	0.640	0.70
127_L	215_V	0.640	0.70
216_V	256_T	0.638	0.70
115_A	168_R	0.637	0.69
116_T	171_T	0.636	0.69
133_S	359_A	0.635	0.69
40_F	43_D	0.635	0.69
92_T	109_I	0.635	0.69
136_Q	139_F	0.635	0.69
310_P	343_V	0.632	0.69
70_K	73_E	0.631	0.69
290_E	293_H	0.630	0.69
135_A	317_A	0.630	0.69
60_M	63_I	0.630	0.69
332_K	343_V	0.628	0.68
181_P	188_V	0.628	0.68
190_P	194_I	0.628	0.68
251_K	256_T	0.628	0.68
128_E	135_A	0.627	0.68
150_G	154_R	0.627	0.68
110_P	347_R	0.627	0.68
255_E	259_A	0.626	0.68
68_R	72_K	0.626	0.68
223_G	260_A	0.625	0.68
241_I	285_V	0.625	0.68
41_R	67_L	0.625	0.68
134_T	172_N	0.625	0.68
316_G	359_A	0.623	0.68
82_V	97_I	0.622	0.68
20_L	28_M	0.619	0.67
297_E	300_K	0.616	0.67
49_M	53_C	0.615	0.67
229_A	305_K	0.612	0.66
216_V	252_Y	0.611	0.66
134_T	191_A	0.611	0.66
236_A	294_Q	0.609	0.66
237_P	279_Y	0.608	0.66
293_H	297_E	0.606	0.66
279_Y	354_A	0.606	0.66
76_E	100_G	0.603	0.65
25_R	199_F	0.602	0.65
236_A	292_A	0.600	0.65
310_P	321_R	0.600	0.65
130_K	244_E	0.599	0.65
263_R	266_E	0.597	0.64
301_D	304_C	0.597	0.64
45_V	67_L	0.594	0.64
212_T	230_L	0.593	0.64
130_K	245_I	0.590	0.64
116_T	276_T	0.588	0.63
152_V	170_I	0.587	0.63
321_R	346_T	0.586	0.63
123_V	140_N	0.584	0.63
113_D	191_A	0.584	0.63
254_I	277_I	0.583	0.63
329_R	336_S	0.583	0.63
23_L	27_Q	0.582	0.62
29_R	32_F	0.581	0.62
32_F	37_E	0.581	0.62
152_V	156_A	0.580	0.62
257_F	261_V	0.577	0.62
293_H	336_S	0.577	0.62
299_L	304_C	0.576	0.62
276_T	305_K	0.575	0.62
119_V	152_V	0.574	0.61
274_R	305_K	0.572	0.61
122_Q	142_N	0.571	0.61
278_E	307_N	0.570	0.61
50_Y	149_I	0.569	0.61
82_V	154_R	0.568	0.61
311_W	319_Y	0.568	0.61
152_V	203_L	0.565	0.60
262_R	298_L	0.564	0.60
46_M	197_D	0.560	0.60
194_I	200_G	0.559	0.59
331_S	343_V	0.556	0.59
44_Q	48_W	0.554	0.59
38_K	44_Q	0.554	0.59
31_F	57_F	0.554	0.59
305_K	340_T	0.552	0.58
40_F	62_D	0.552	0.58
229_A	269_N	0.552	0.58
116_T	174_V	0.550	0.58
114_R	178_M	0.549	0.58
44_Q	68_R	0.549	0.58
288_G	326_R	0.549	0.58
135_A	178_M	0.549	0.58
156_A	169_P	0.549	0.58
134_T	359_A	0.549	0.58
288_G	292_A	0.548	0.58
315_P	361_D	0.548	0.58
106_T	119_V	0.548	0.58
330_F	353_A	0.547	0.58
114_R	191_A	0.546	0.58
310_P	327_I	0.545	0.57
95_W	106_T	0.544	0.57
95_W	108_Y	0.544	0.57
50_Y	78_R	0.541	0.57
281_M	343_V	0.540	0.57
91_G	110_P	0.539	0.57
60_M	68_R	0.539	0.57
44_Q	206_R	0.539	0.57
262_R	266_E	0.538	0.57
159_V	170_I	0.537	0.56
49_M	57_F	0.537	0.56
282_L	322_S	0.536	0.56
53_C	157_K	0.535	0.56
46_M	200_G	0.535	0.56
92_T	351_I	0.535	0.56
26_Q	31_F	0.534	0.56
133_S	235_H	0.533	0.56
25_R	46_M	0.533	0.56
187_N	191_A	0.532	0.56
119_V	175_M	0.531	0.56
239_D	254_I	0.531	0.56
204_S	227_D	0.531	0.56
108_Y	170_I	0.531	0.56
111_E	305_K	0.530	0.55
44_Q	62_D	0.530	0.55
99_V	102_Q	0.529	0.55
21_L	49_M	0.527	0.55
58_D	65_K	0.527	0.55
223_G	265_L	0.524	0.55
218_A	257_F	0.523	0.54
235_H	280_V	0.522	0.54
137_Q	353_A	0.522	0.54
187_N	190_P	0.521	0.54
83_V	329_R	0.521	0.54
48_W	276_T	0.520	0.54
109_I	116_T	0.520	0.54
237_P	298_L	0.519	0.54
20_L	77_I	0.517	0.54
130_K	246_V	0.516	0.53
114_R	231_A	0.516	0.53
250_K	253_N	0.515	0.53
133_S	136_Q	0.511	0.53
323_S	328_D	0.510	0.53
240_E	294_Q	0.509	0.52
116_T	175_M	0.509	0.52
159_V	168_R	0.508	0.52
111_E	347_R	0.507	0.52
235_H	322_S	0.507	0.52
175_M	178_M	0.506	0.52
189_V	226_I	0.506	0.52
58_D	68_R	0.505	0.52
18_I	33_K	0.504	0.52
28_M	50_Y	0.504	0.52
258_L	299_L	0.503	0.52
29_R	63_I	0.501	0.51
78_R	150_G	0.501	0.51
266_E	269_N	0.500	0.51
306_I	341_T	0.500	0.51

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3rfaA	1	0.9349	100	0.394	Contact Map
2yx0A	1	0.7656	100	0.727	Contact Map
2z2uA	1	0.6667	100	0.728	Contact Map
2a5hA	4	0.875	100	0.79	Contact Map
4r33A	2	0.8229	100	0.819	Contact Map
3c8fA	1	0.5781	99.9	0.827	Contact Map
4wcxA	1	0.849	99.9	0.828	Contact Map
4rtbA	2	0.7943	99.9	0.836	Contact Map
3iixA	1	0.763	99.9	0.846	Contact Map
3t7vA	1	0.7552	99.9	0.848	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0107 seconds.