DTPB - ECOLI - GREMLIN Contacts

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DTPB - Dipeptide and tripeptide permease B

UniProt:	P36837	Sequences: MNTTTPMGMLQQPRPFFMIFFVELWERFGYYGVQGVLAVFFVKQLGFSQEQAFVTFGAFAALVYGLISIGGYVGDHLLGTKRTIVLGALVLAIGYFMTGMSLLKPDLIFIALGTIAVGNGLFKANPASLLSKCYPPKDPRLDGAFTLFYMSINIGSLIALSLAPVIADRFGYSVTYNLCGAGLIIALLVYIACRGMVKDIGSEPDFRPMSFSKLLYVLLGSVVMIFVCAWLMHNVEVANLVLIVLSIVVTIIFFRQAFKLDKTGRNKMFVAFVLMLEAVVFYILYAQMPTSLNFFAINNVHHEILGFSINPVSFQALNPFWVVLASPILAGIYTHLGNKGKDLSMPMKFTLGMFMCSLGFLTAAAAGMWFADAQGLTSPWFIVLVYLFQSLGELFISALGLAMIAALVPQHLMGFILGMWFLTQAAAFLLGGYVATFTAVPDNITDPLETLPVYTNVFGKIGLVTLGVAVVMLLMVPWLKRMIATPESH	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG12232
Length:	489 (461)
Sequences:	4651 (2906)
Seq/√Len:	135.4

ECOLI - DTPB DTPD YJDL DTPA
BACSU - YCLF

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
166_I	178_L	4.318	1.00
364_A	459_G	3.548	1.00
362_T	388_F	3.543	1.00
281_F	392_G	3.455	1.00
314_F	379_P	3.439	1.00
73_V	78_L	3.387	1.00
49_Q	298_N	3.234	1.00
78_L	83_T	3.125	1.00
93_I	114_T	2.962	1.00
302_H	308_S	2.953	1.00
351_L	395_F	2.879	1.00
73_V	77_L	2.869	1.00
463_L	467_G	2.847	1.00
291_S	296_A	2.810	1.00
293_N	296_A	2.741	1.00
97_M	111_A	2.706	1.00
321_W	387_L	2.680	1.00
97_M	114_T	2.637	1.00
400_G	420_W	2.585	1.00
354_F	469_A	2.528	1.00
167_A	312_V	2.525	1.00
78_L	86_L	2.524	1.00
29_G	95_Y	2.489	1.00
247_I	250_T	2.483	1.00
92_A	184_I	2.472	1.00
198_K	201_G	2.464	1.00
89_L	93_I	2.453	1.00
87_G	121_L	2.441	1.00
383_V	387_L	2.439	1.00
355_M	391_L	2.425	1.00
39_V	293_N	2.374	1.00
303_E	308_S	2.363	1.00
258_F	262_K	2.363	1.00
23_E	27_R	2.299	1.00
296_A	382_I	2.231	1.00
168_D	311_P	2.224	1.00
98_T	111_A	2.137	1.00
328_I	332_I	2.131	1.00
26_E	123_K	2.128	1.00
361_L	462_G	2.126	1.00
99_G	180_G	2.121	1.00
344_S	347_M	2.119	1.00
250_T	253_F	2.109	1.00
81_K	194_R	2.060	1.00
362_T	384_L	2.037	1.00
85_V	191_I	2.020	1.00
325_A	391_L	2.018	1.00
470_V	474_L	2.013	1.00
291_S	295_F	2.011	1.00
282_Y	397_S	2.004	1.00
30_Y	60_A	1.995	1.00
247_I	251_I	1.989	1.00
23_E	26_E	1.978	1.00
145_F	405_A	1.977	1.00
471_V	475_M	1.925	1.00
38_A	42_V	1.903	1.00
335_H	339_K	1.870	1.00
466_L	470_V	1.866	1.00
357_S	466_L	1.860	1.00
317_L	383_V	1.860	1.00
328_I	331_G	1.857	1.00
258_F	263_T	1.813	1.00
67_I	74_G	1.793	1.00
66_L	69_I	1.786	1.00
130_L	144_A	1.786	1.00
47_F	55_T	1.749	1.00
23_E	123_K	1.736	1.00
354_F	358_L	1.726	1.00
94_G	115_I	1.712	1.00
91_L	122_F	1.674	1.00
49_Q	294_F	1.670	1.00
368_M	455_T	1.670	1.00
150_M	323_V	1.663	1.00
332_I	336_L	1.655	1.00
318_N	390_S	1.646	1.00
262_K	265_R	1.643	1.00
194_R	199_D	1.638	1.00
235_V	238_A	1.615	1.00
318_N	322_V	1.611	1.00
66_L	116_A	1.597	1.00
324_L	328_I	1.596	1.00
206_F	212_S	1.560	1.00
293_N	297_I	1.557	1.00
358_L	388_F	1.550	1.00
236_E	239_N	1.540	1.00
43_K	172_Y	1.539	1.00
228_C	231_L	1.530	1.00
171_G	174_V	1.529	1.00
96_F	180_G	1.527	1.00
39_V	311_P	1.527	1.00
280_V	468_V	1.522	1.00
209_M	212_S	1.521	1.00
157_L	323_V	1.517	1.00
239_N	242_L	1.514	1.00
48_S	51_Q	1.500	1.00
310_N	313_S	1.487	1.00
127_A	421_F	1.485	1.00
174_V	177_N	1.479	1.00
469_A	473_L	1.478	1.00
148_F	152_I	1.475	1.00
357_S	469_A	1.457	1.00
56_F	290_T	1.446	1.00
283_I	427_A	1.435	1.00
477_P	480_K	1.434	1.00
197_V	201_G	1.423	1.00
350_T	469_A	1.419	1.00
359_G	389_Q	1.414	1.00
216_Y	220_G	1.407	1.00
41_F	56_F	1.405	1.00
377_T	381_F	1.399	1.00
278_A	423_T	1.394	1.00
246_S	250_T	1.391	1.00
214_L	218_L	1.387	1.00
474_L	478_W	1.385	1.00
164_P	312_V	1.384	1.00
367_G	370_F	1.379	1.00
229_A	232_M	1.374	1.00
94_G	118_G	1.350	1.00
460_K	464_V	1.344	1.00
336_L	339_K	1.337	1.00
24_L	151_S	1.336	1.00
86_L	89_L	1.326	1.00
299_N	375_G	1.326	1.00
255_R	268_M	1.324	1.00
285_Y	288_M	1.322	1.00
150_M	326_S	1.307	1.00
257_A	265_R	1.304	1.00
203_E	206_F	1.294	1.00
54_V	436_T	1.287	1.00
460_K	463_L	1.284	1.00
132_K	405_A	1.283	1.00
153_N	318_N	1.277	1.00
38_A	52_A	1.274	1.00
363_A	385_V	1.273	1.00
302_H	311_P	1.268	1.00
258_F	265_R	1.266	1.00
238_A	241_V	1.257	1.00
350_T	473_L	1.254	1.00
18_M	193_C	1.251	1.00
70_G	120_G	1.249	1.00
166_I	170_F	1.247	1.00
217_V	221_S	1.246	1.00
219_L	223_V	1.245	1.00
205_D	208_P	1.245	1.00
343_L	351_L	1.240	1.00
355_M	392_G	1.237	1.00
331_G	335_H	1.236	1.00
152_I	421_F	1.234	1.00
322_V	393_E	1.230	1.00
321_W	390_S	1.229	1.00
149_Y	393_E	1.229	1.00
92_A	96_F	1.228	1.00
111_A	115_I	1.221	1.00
38_A	294_F	1.220	1.00
32_G	163_A	1.218	1.00
397_S	401_L	1.218	1.00
162_L	178_L	1.216	1.00
119_N	123_K	1.207	1.00
299_N	376_L	1.197	1.00
40_F	101_S	1.195	1.00
24_L	154_I	1.192	1.00
259_K	263_T	1.191	1.00
346_P	476_V	1.191	1.00
206_F	211_F	1.185	0.99
92_A	187_L	1.184	0.99
301_H	376_L	1.182	0.99
201_G	206_F	1.182	0.99
347_M	476_V	1.174	0.99
164_P	313_S	1.160	0.99
459_G	463_L	1.158	0.99
27_R	123_K	1.158	0.99
163_A	166_I	1.158	0.99
207_R	213_K	1.153	0.99
366_A	381_F	1.151	0.99
25_W	182_G	1.147	0.99
27_R	30_Y	1.147	0.99
226_F	232_M	1.144	0.99
78_L	82_R	1.143	0.99
119_N	122_F	1.140	0.99
337_G	342_D	1.139	0.99
336_L	341_K	1.139	0.99
142_D	402_A	1.138	0.99
414_G	418_G	1.138	0.99
365_A	369_W	1.134	0.99
249_V	253_F	1.133	0.99
292_L	296_A	1.132	0.99
127_A	148_F	1.129	0.99
149_Y	322_V	1.129	0.99
134_Y	144_A	1.126	0.99
23_E	148_F	1.125	0.99
349_F	396_I	1.124	0.99
73_V	83_T	1.120	0.99
181_A	185_I	1.107	0.99
254_F	257_A	1.103	0.99
260_L	265_R	1.100	0.99
123_K	421_F	1.097	0.99
458_F	461_I	1.088	0.99
80_T	132_K	1.084	0.99
307_F	313_S	1.082	0.99
387_L	391_L	1.079	0.99
235_V	240_L	1.075	0.99
233_H	238_A	1.075	0.99
228_C	232_M	1.074	0.99
315_Q	319_P	1.072	0.99
165_V	170_F	1.070	0.99
152_I	401_L	1.068	0.99
71_G	414_G	1.066	0.99
156_S	319_P	1.063	0.99
357_S	361_L	1.058	0.99
288_M	389_Q	1.057	0.99
290_T	296_A	1.049	0.99
209_M	213_K	1.047	0.99
236_E	240_L	1.047	0.99
207_R	211_F	1.045	0.99
352_G	396_I	1.044	0.99
101_S	107_L	1.043	0.99
26_E	31_Y	1.041	0.99
188_L	192_A	1.041	0.99
403_M	479_L	1.039	0.99
322_V	327_P	1.037	0.99
210_S	213_K	1.034	0.99
259_K	265_R	1.033	0.99
303_E	306_G	1.033	0.99
326_S	398_A	1.025	0.98
239_N	243_I	1.023	0.98
456_N	459_G	1.017	0.98
63_V	116_A	1.015	0.98
161_S	313_S	1.012	0.98
66_L	120_G	1.007	0.98
302_H	310_N	1.006	0.98
23_E	122_F	1.006	0.98
34_Q	56_F	1.005	0.98
130_L	133_C	1.005	0.98
41_F	108_I	1.004	0.98
63_V	66_L	1.003	0.98
177_N	181_A	1.002	0.98
192_A	195_G	1.001	0.98
208_P	212_S	1.001	0.98
10_L	13_P	1.000	0.98
91_L	119_N	0.997	0.98
263_T	266_N	0.996	0.98
257_A	263_T	0.995	0.98
34_Q	286_A	0.994	0.98
437_F	441_P	0.985	0.98
336_L	343_L	0.984	0.98
47_F	51_Q	0.983	0.98
206_F	210_S	0.976	0.98
358_L	362_T	0.974	0.98
245_L	248_V	0.973	0.98
235_V	239_N	0.972	0.98
477_P	481_R	0.971	0.98
262_K	266_N	0.964	0.98
25_W	126_P	0.962	0.98
55_T	109_F	0.961	0.98
127_A	417_L	0.957	0.98
260_L	264_G	0.954	0.98
237_V	241_V	0.954	0.98
261_D	264_G	0.954	0.98
220_G	223_V	0.952	0.98
216_Y	219_L	0.952	0.98
202_S	205_D	0.950	0.98
335_H	338_N	0.950	0.98
223_V	243_I	0.949	0.98
149_Y	153_N	0.949	0.98
212_S	262_K	0.945	0.97
300_V	382_I	0.945	0.97
27_R	31_Y	0.939	0.97
43_K	168_D	0.939	0.97
257_A	260_L	0.938	0.97
131_S	405_A	0.938	0.97
478_W	482_M	0.937	0.97
177_N	180_G	0.937	0.97
378_S	381_F	0.933	0.97
285_Y	390_S	0.931	0.97
325_A	387_L	0.928	0.97
283_I	430_L	0.927	0.97
234_N	239_N	0.925	0.97
235_V	241_V	0.920	0.97
255_R	265_R	0.919	0.97
54_V	432_G	0.919	0.97
42_V	294_F	0.916	0.97
94_G	98_T	0.914	0.97
393_E	397_S	0.908	0.97
62_L	429_L	0.908	0.97
71_G	418_G	0.907	0.97
12_Q	16_F	0.900	0.97
92_A	180_G	0.897	0.97
299_N	454_Y	0.896	0.96
42_V	49_Q	0.895	0.96
40_F	108_I	0.895	0.96
294_F	297_I	0.892	0.96
204_P	220_G	0.889	0.96
158_I	161_S	0.887	0.96
259_K	262_K	0.886	0.96
39_V	43_K	0.884	0.96
397_S	420_W	0.883	0.96
48_S	52_A	0.882	0.96
292_L	297_I	0.881	0.96
247_I	252_I	0.880	0.96
325_A	394_L	0.880	0.96
317_L	321_W	0.880	0.96
307_F	310_N	0.877	0.96
288_M	393_E	0.876	0.96
234_N	237_V	0.875	0.96
64_Y	123_K	0.871	0.96
321_W	383_V	0.869	0.96
85_V	88_A	0.868	0.96
397_S	400_G	0.865	0.96
51_Q	54_V	0.865	0.96
20_F	151_S	0.863	0.96
260_L	263_T	0.862	0.96
284_L	465_T	0.862	0.96
284_L	389_Q	0.858	0.96
122_F	126_P	0.855	0.95
281_F	322_V	0.852	0.95
278_A	420_W	0.851	0.95
362_T	385_V	0.850	0.95
309_I	313_S	0.849	0.95
255_R	259_K	0.849	0.95
433_Y	437_F	0.849	0.95
247_I	253_F	0.849	0.95
457_V	461_I	0.847	0.95
207_R	210_S	0.843	0.95
24_L	152_I	0.842	0.95
64_Y	421_F	0.842	0.95
292_L	385_V	0.841	0.95
347_M	350_T	0.839	0.95
57_G	431_G	0.839	0.95
237_V	240_L	0.837	0.95
296_A	300_V	0.837	0.95
326_S	330_A	0.837	0.95
467_G	471_V	0.834	0.95
13_P	16_F	0.830	0.95
211_F	215_L	0.829	0.95
164_P	167_A	0.828	0.95
93_I	97_M	0.828	0.95
300_V	379_P	0.827	0.95
329_L	391_L	0.827	0.95
355_M	388_F	0.826	0.94
143_G	330_A	0.826	0.94
220_G	225_I	0.820	0.94
475_M	478_W	0.819	0.94
23_E	152_I	0.817	0.94
331_G	334_T	0.813	0.94
26_E	183_L	0.813	0.94
127_A	401_L	0.812	0.94
367_G	455_T	0.811	0.94
274_L	349_F	0.810	0.94
402_A	406_A	0.808	0.94
284_L	356_C	0.806	0.94
103_L	173_S	0.805	0.94
257_A	262_K	0.805	0.94
277_E	472_M	0.804	0.94
75_D	79_G	0.804	0.94
329_L	332_I	0.803	0.94
407_L	483_I	0.802	0.94
68_S	72_Y	0.801	0.94
167_A	171_G	0.799	0.93
285_Y	397_S	0.798	0.93
221_S	226_F	0.796	0.93
349_F	400_G	0.792	0.93
410_Q	413_M	0.792	0.93
29_G	119_N	0.791	0.93
235_V	242_L	0.790	0.93
168_D	312_V	0.788	0.93
147_L	150_M	0.787	0.93
234_N	241_V	0.785	0.93
285_Y	318_N	0.784	0.93
201_G	204_P	0.783	0.93
132_K	413_M	0.783	0.93
286_A	428_F	0.782	0.93
291_S	294_F	0.781	0.93
275_M	404_I	0.779	0.93
68_S	418_G	0.779	0.93
25_W	28_F	0.778	0.93
27_R	152_I	0.776	0.92
72_Y	77_L	0.771	0.92
18_M	196_M	0.770	0.92
309_I	379_P	0.770	0.92
160_L	316_A	0.769	0.92
292_L	386_Y	0.768	0.92
438_T	460_K	0.768	0.92
302_H	379_P	0.767	0.92
193_C	196_M	0.764	0.92
234_N	238_A	0.764	0.92
467_G	474_L	0.763	0.92
148_F	393_E	0.762	0.92
38_A	293_N	0.761	0.92
63_V	125_N	0.761	0.92
325_A	328_I	0.761	0.92
220_G	224_M	0.761	0.92
286_A	424_Q	0.760	0.92
215_L	219_L	0.755	0.91
162_L	166_I	0.753	0.91
288_M	386_Y	0.751	0.91
165_V	169_R	0.751	0.91
127_A	152_I	0.750	0.91
291_S	297_I	0.748	0.91
36_V	175_T	0.747	0.91
12_Q	15_P	0.747	0.91
239_N	251_I	0.747	0.91
90_V	117_V	0.746	0.91
347_M	473_L	0.744	0.91
375_G	378_S	0.744	0.91
350_T	354_F	0.741	0.91
281_F	396_I	0.741	0.91
85_V	187_L	0.736	0.90
363_A	366_A	0.734	0.90
157_L	319_P	0.734	0.90
148_F	401_L	0.731	0.90
173_S	177_N	0.729	0.90
221_S	225_I	0.727	0.90
350_T	476_V	0.726	0.90
213_K	217_V	0.723	0.90
162_L	165_V	0.722	0.89
283_I	434_V	0.721	0.89
346_P	481_R	0.721	0.89
243_I	247_I	0.718	0.89
236_E	243_I	0.714	0.89
39_V	298_N	0.712	0.89
227_V	232_M	0.712	0.89
82_R	86_L	0.712	0.89
364_A	455_T	0.711	0.89
215_L	220_G	0.709	0.89
26_E	30_Y	0.709	0.89
295_F	382_I	0.709	0.89
90_V	111_A	0.709	0.89
352_G	392_G	0.708	0.89
430_L	433_Y	0.706	0.88
95_Y	180_G	0.701	0.88
245_L	249_V	0.699	0.88
318_N	393_E	0.697	0.88
261_D	265_R	0.697	0.88
234_N	242_L	0.694	0.88
26_E	287_Q	0.694	0.88
234_N	270_V	0.692	0.87
230_W	233_H	0.692	0.87
364_A	461_I	0.691	0.87
220_G	231_L	0.690	0.87
236_E	241_V	0.690	0.87
248_V	252_I	0.689	0.87
281_F	318_N	0.689	0.87
427_A	430_L	0.689	0.87
131_S	145_F	0.688	0.87
193_C	197_V	0.686	0.87
246_S	249_V	0.686	0.87
462_G	466_L	0.686	0.87
280_V	464_V	0.685	0.87
230_W	234_N	0.684	0.87
274_L	403_M	0.684	0.87
217_V	222_V	0.683	0.87
366_A	385_V	0.682	0.87
290_T	435_A	0.681	0.87
365_A	368_M	0.681	0.87
257_A	264_G	0.680	0.86
99_G	177_N	0.678	0.86
222_V	226_F	0.678	0.86
30_Y	123_K	0.677	0.86
255_R	262_K	0.677	0.86
60_A	63_V	0.676	0.86
74_G	84_I	0.675	0.86
240_L	243_I	0.675	0.86
217_V	241_V	0.674	0.86
438_T	442_D	0.674	0.86
83_T	121_L	0.673	0.86
478_W	481_R	0.672	0.86
153_N	319_P	0.670	0.86
223_V	226_F	0.669	0.86
170_F	310_N	0.667	0.85
254_F	268_M	0.667	0.85
39_V	42_V	0.665	0.85
86_L	191_I	0.665	0.85
85_V	89_L	0.664	0.85
38_A	53_F	0.664	0.85
244_V	250_T	0.663	0.85
191_I	194_R	0.661	0.85
220_G	248_V	0.660	0.85
190_Y	194_R	0.659	0.85
14_R	17_F	0.659	0.85
124_A	128_S	0.658	0.85
233_H	242_L	0.656	0.84
258_F	261_D	0.656	0.84
64_Y	153_N	0.654	0.84
333_Y	342_D	0.654	0.84
279_V	427_A	0.653	0.84
236_E	242_L	0.652	0.84
274_L	475_M	0.652	0.84
288_M	318_N	0.651	0.84
62_L	116_A	0.649	0.84
213_K	241_V	0.647	0.84
204_P	208_P	0.647	0.84
364_A	368_M	0.644	0.83
88_A	183_L	0.644	0.83
329_L	394_L	0.644	0.83
471_V	474_L	0.642	0.83
233_H	236_E	0.642	0.83
65_G	428_F	0.641	0.83
472_M	476_V	0.640	0.83
47_F	105_P	0.640	0.83
216_Y	257_A	0.638	0.83
157_L	320_F	0.637	0.83
36_V	41_F	0.637	0.83
290_T	294_F	0.636	0.83
218_L	221_S	0.635	0.83
238_A	246_S	0.635	0.83
84_I	190_Y	0.635	0.83
216_Y	223_V	0.633	0.82
153_N	156_S	0.633	0.82
288_M	359_G	0.633	0.82
255_R	260_L	0.632	0.82
241_V	246_S	0.632	0.82
153_N	393_E	0.631	0.82
126_P	152_I	0.631	0.82
287_Q	291_S	0.631	0.82
238_A	242_L	0.628	0.82
128_S	417_L	0.627	0.82
167_A	170_F	0.626	0.82
40_F	330_A	0.626	0.82
224_M	227_V	0.625	0.82
53_F	438_T	0.624	0.81
255_R	269_F	0.624	0.81
42_V	297_I	0.623	0.81
149_Y	318_N	0.623	0.81
239_N	266_N	0.620	0.81
271_A	404_I	0.619	0.81
167_A	172_Y	0.618	0.81
334_T	337_G	0.617	0.81
456_N	463_L	0.616	0.81
350_T	472_M	0.616	0.81
226_F	231_L	0.615	0.80
54_V	58_A	0.615	0.80
84_I	414_G	0.614	0.80
149_Y	315_Q	0.614	0.80
364_A	367_G	0.612	0.80
17_F	21_F	0.612	0.80
126_P	129_L	0.611	0.80
125_N	414_G	0.611	0.80
168_D	302_H	0.609	0.80
243_I	246_S	0.608	0.80
57_G	432_G	0.607	0.80
337_G	340_G	0.607	0.80
70_G	134_Y	0.606	0.80
122_F	125_N	0.606	0.80
333_Y	337_G	0.606	0.80
333_Y	343_L	0.606	0.80
224_M	230_W	0.604	0.79
127_A	397_S	0.604	0.79
212_S	215_L	0.604	0.79
31_Y	319_P	0.604	0.79
20_F	24_L	0.603	0.79
431_G	461_I	0.602	0.79
18_M	189_V	0.602	0.79
282_Y	285_Y	0.601	0.79
96_F	100_M	0.601	0.79
249_V	252_I	0.600	0.79
396_I	420_W	0.600	0.79
27_R	183_L	0.598	0.79
145_F	274_L	0.598	0.79
22_V	151_S	0.596	0.78
92_A	150_M	0.594	0.78
36_V	49_Q	0.592	0.78
99_G	187_L	0.591	0.78
27_R	119_N	0.590	0.78
320_F	324_L	0.590	0.78
356_C	359_G	0.590	0.78
153_N	397_S	0.589	0.78
23_E	32_G	0.588	0.77
95_Y	183_L	0.587	0.77
148_F	408_V	0.586	0.77
294_F	298_N	0.584	0.77
115_I	120_G	0.584	0.77
248_V	251_I	0.584	0.77
165_V	312_V	0.583	0.77
122_F	148_F	0.581	0.77
339_K	361_L	0.581	0.77
203_E	210_S	0.581	0.77
135_P	198_K	0.580	0.77
174_V	179_C	0.580	0.77
339_K	342_D	0.580	0.77
217_V	224_M	0.580	0.77
254_F	258_F	0.580	0.77
73_V	250_T	0.579	0.76
125_N	179_C	0.579	0.76
203_E	207_R	0.578	0.76
159_A	431_G	0.576	0.76
208_P	211_F	0.576	0.76
27_R	32_G	0.574	0.76
355_M	395_F	0.574	0.76
333_Y	340_G	0.573	0.76
222_V	225_I	0.571	0.75
270_V	482_M	0.570	0.75
366_A	377_T	0.569	0.75
150_M	154_I	0.568	0.75
335_H	340_G	0.567	0.75
42_V	52_A	0.567	0.75
273_V	479_L	0.566	0.75
356_C	465_T	0.565	0.75
280_V	392_G	0.562	0.74
361_L	365_A	0.562	0.74
15_P	18_M	0.561	0.74
224_M	229_A	0.561	0.74
184_I	211_F	0.560	0.74
53_F	290_T	0.558	0.74
234_N	240_L	0.555	0.73
435_A	438_T	0.555	0.73
255_R	258_F	0.554	0.73
95_Y	99_G	0.553	0.73
309_I	387_L	0.553	0.73
237_V	242_L	0.551	0.73
233_H	239_N	0.551	0.73
64_Y	318_N	0.551	0.73
230_W	235_V	0.550	0.73
69_I	427_A	0.549	0.73
142_D	348_K	0.549	0.73
322_V	326_S	0.548	0.72
172_Y	176_Y	0.548	0.72
64_Y	148_F	0.548	0.72
56_F	428_F	0.548	0.72
106_D	110_I	0.547	0.72
284_L	461_I	0.547	0.72
27_R	148_F	0.547	0.72
239_N	256_Q	0.546	0.72
213_K	216_Y	0.546	0.72
299_N	374_Q	0.546	0.72
257_A	261_D	0.545	0.72
146_T	330_A	0.545	0.72
41_F	45_L	0.544	0.72
158_I	162_L	0.543	0.72
91_L	115_I	0.542	0.72
358_L	361_L	0.542	0.72
220_G	228_C	0.540	0.71
213_K	220_G	0.540	0.71
150_M	327_P	0.539	0.71
456_N	460_K	0.539	0.71
401_L	417_L	0.537	0.71
460_K	467_G	0.537	0.71
43_K	297_I	0.536	0.71
26_E	32_G	0.536	0.71
25_W	29_G	0.535	0.71
80_T	414_G	0.533	0.70
465_T	469_A	0.533	0.70
284_L	462_G	0.533	0.70
149_Y	152_I	0.533	0.70
454_Y	457_V	0.532	0.70
88_A	179_C	0.531	0.70
14_R	196_M	0.531	0.70
222_V	227_V	0.530	0.70
466_L	469_A	0.530	0.70
64_Y	152_I	0.529	0.70
49_Q	53_F	0.528	0.70
213_K	228_C	0.528	0.70
185_I	189_V	0.527	0.69
206_F	209_M	0.527	0.69
61_A	429_L	0.527	0.69
32_G	79_G	0.526	0.69
318_N	389_Q	0.525	0.69
411_H	418_G	0.523	0.69
53_F	294_F	0.522	0.69
103_L	115_I	0.521	0.69
212_S	228_C	0.520	0.68
215_L	240_L	0.519	0.68
244_V	248_V	0.516	0.68
23_E	30_Y	0.516	0.68
94_G	111_A	0.515	0.68
59_F	63_V	0.515	0.68
122_F	127_A	0.515	0.68
35_G	160_L	0.515	0.68
238_A	252_I	0.514	0.68
26_E	122_F	0.513	0.67
234_N	243_I	0.512	0.67
437_F	440_V	0.510	0.67
354_F	470_V	0.510	0.67
152_I	397_S	0.509	0.67
168_D	310_N	0.509	0.67
56_F	112_L	0.508	0.67
30_Y	34_Q	0.508	0.67
50_E	53_F	0.508	0.67
145_F	408_V	0.508	0.67
82_R	231_L	0.508	0.67
12_Q	134_Y	0.507	0.67
393_E	400_G	0.507	0.67
66_L	87_G	0.506	0.66
28_F	182_G	0.506	0.66
29_G	33_V	0.506	0.66
61_A	367_G	0.504	0.66
161_S	316_A	0.504	0.66
88_A	125_N	0.504	0.66
157_L	316_A	0.503	0.66
218_L	227_V	0.503	0.66
125_N	134_Y	0.501	0.66
65_G	69_I	0.501	0.66
379_P	382_I	0.500	0.65

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4oh3A	2	0.9714	100	0.521	Contact Map
4uvmA	1	0.9591	100	0.53	Contact Map
4q65A	1	0.8773	100	0.596	Contact Map
4tphA	2	0.8916	100	0.614	Contact Map
4ikvA	1	0.955	100	0.632	Contact Map
4xnjA	1	0.9121	100	0.643	Contact Map
4w6vA	1	0.9387	100	0.731	Contact Map
2cfqA	1	0.8364	99.9	0.772	Contact Map
3wdoA	1	0.816	99.9	0.772	Contact Map
4pypA	1	0.8773	99.9	0.776	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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