PTTBC - ECOLI - GREMLIN Contacts

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PTTBC - PTS system trehalose-specific EIIBC component

UniProt:	P36672	Sequences: MMSKINQTDIDRLIELVGGRGNIATVSHCITRLRFVLNQPANARPKEIEQLPMVKGCFTNAGQFQVVIGTNVGDYYQALIASTGQAQVDKEQVKKAARHNMKWHEQLISHFAVIFFPLLPALISGGLILGFRNVIGDLPMSNGQTLAQMYPSLQTIYDFLWLIGEAIFFYLPVGICWSAVKKMGGTPILGIVLGVTLVSPQLMNAYLLGQQLPEVWDFGMFSIAKVGYQAQVIPALLAGLALGVIETRLKRIVPDYLYLVVVPVCSLILAVFLAHALIGPFGRMIGDGVAFAVRHLMTGSFAPIGAALFGFLYAPLVITGVHQTTLAIDLQMIQSMGGTPVWPLIALSNIAQGSAVIGIIISSRKHNEREISVPAAISAWLGVTEPAMYGINLKYRFPMLCAMIGSGLAGLLCGLNGVMANGIGVGGLPGILSIQPSYWQVFALAMAIAIIIPIVLTSFIYQRKYRLGTLDIV	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG12127
Length:	473 (440)
Sequences:	4098 (2329)
Seq/√Len:	111.0

ECOLI - PTTBC PTV3B PTIBC PTYBC PTOCB PTGCB
BACSU - PTV3B PTSBC PTTBC SACX PTXBC PTWCB PTOCB

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
44_R	47_E	4.509	1.00
412_L	448_I	4.116	1.00
405_G	452_I	3.838	1.00
311_F	407_G	3.751	1.00
8_T	12_R	3.672	1.00
358_G	454_I	3.559	1.00
238_A	274_A	3.386	1.00
265_C	269_L	3.262	1.00
40_P	59_T	3.227	1.00
37_L	43_A	3.214	1.00
14_I	79_L	3.052	1.00
9_D	51_L	2.960	1.00
16_L	44_R	2.931	1.00
46_K	49_E	2.911	1.00
176_C	190_G	2.862	1.00
45_P	64_F	2.819	1.00
242_L	266_S	2.780	1.00
412_L	441_V	2.759	1.00
39_Q	42_N	2.723	1.00
408_L	452_I	2.687	1.00
253_V	261_V	2.517	1.00
56_G	67_V	2.493	1.00
352_Q	392_N	2.476	1.00
401_C	460_I	2.450	1.00
101_M	106_Q	2.448	1.00
363_S	368_E	2.428	1.00
20_R	84_G	2.427	1.00
35_F	66_V	2.403	1.00
78_A	81_A	2.361	1.00
24_A	38_N	2.335	1.00
177_W	191_I	2.311	1.00
332_M	339_T	2.302	1.00
249_L	265_C	2.295	1.00
248_R	252_I	2.272	1.00
16_L	51_L	2.263	1.00
16_L	47_E	2.241	1.00
45_P	49_E	2.240	1.00
45_P	59_T	2.207	1.00
52_P	367_N	2.191	1.00
412_L	416_N	2.169	1.00
35_F	79_L	2.167	1.00
250_K	258_Y	2.158	1.00
78_A	82_S	2.139	1.00
416_N	441_V	2.125	1.00
241_A	273_L	2.115	1.00
443_A	447_A	2.078	1.00
173_V	195_V	2.067	1.00
17_V	35_F	2.060	1.00
26_V	79_L	2.040	1.00
177_W	187_P	2.015	1.00
12_R	51_L	2.003	1.00
131_F	135_I	1.955	1.00
11_D	82_S	1.942	1.00
14_I	83_T	1.938	1.00
310_G	406_S	1.931	1.00
26_V	35_F	1.930	1.00
13_L	48_I	1.890	1.00
110_H	183_M	1.828	1.00
400_L	404_I	1.817	1.00
25_T	36_V	1.804	1.00
257_L	261_V	1.783	1.00
455_V	459_F	1.763	1.00
48_I	51_L	1.738	1.00
284_M	288_G	1.733	1.00
360_I	373_V	1.730	1.00
244_V	248_R	1.717	1.00
28_H	76_Y	1.716	1.00
413_C	445_A	1.701	1.00
47_E	50_Q	1.700	1.00
354_S	450_I	1.700	1.00
357_I	376_A	1.695	1.00
244_V	247_T	1.692	1.00
12_R	15_E	1.685	1.00
354_S	453_P	1.667	1.00
401_C	456_L	1.664	1.00
441_V	444_L	1.660	1.00
76_Y	80_I	1.656	1.00
356_V	387_A	1.649	1.00
307_A	411_L	1.637	1.00
129_L	165_E	1.636	1.00
388_M	399_M	1.634	1.00
173_V	191_I	1.632	1.00
249_L	253_V	1.628	1.00
237_L	282_G	1.623	1.00
456_L	460_I	1.616	1.00
353_G	379_A	1.596	1.00
185_G	239_G	1.593	1.00
338_G	419_M	1.593	1.00
395_Y	398_P	1.580	1.00
306_A	410_G	1.578	1.00
401_C	405_G	1.567	1.00
11_D	15_E	1.554	1.00
13_L	68_I	1.550	1.00
135_I	140_M	1.539	1.00
10_I	79_L	1.533	1.00
245_I	270_A	1.531	1.00
287_D	291_F	1.515	1.00
362_S	461_Y	1.511	1.00
315_P	403_M	1.505	1.00
240_L	243_G	1.501	1.00
17_V	37_L	1.484	1.00
103_W	106_Q	1.482	1.00
109_S	182_K	1.481	1.00
181_K	187_P	1.465	1.00
58_F	67_V	1.464	1.00
261_V	265_C	1.461	1.00
452_I	456_L	1.449	1.00
451_I	455_V	1.445	1.00
288_G	292_A	1.436	1.00
307_A	407_G	1.433	1.00
365_K	368_E	1.416	1.00
23_I	85_Q	1.399	1.00
314_A	349_N	1.392	1.00
26_V	80_I	1.384	1.00
311_F	315_P	1.380	1.00
368_E	395_Y	1.374	1.00
457_T	461_Y	1.371	1.00
177_W	188_I	1.360	1.00
180_V	239_G	1.359	1.00
179_A	240_L	1.348	1.00
395_Y	462_Q	1.345	1.00
14_I	82_S	1.339	1.00
127_L	264_V	1.336	1.00
240_L	244_V	1.310	0.99
193_L	267_L	1.296	0.99
411_L	415_L	1.276	0.99
306_A	411_L	1.274	0.99
159_F	223_I	1.268	0.99
245_I	269_L	1.258	0.99
405_G	453_P	1.236	0.99
412_L	444_L	1.235	0.99
103_W	107_L	1.229	0.99
190_G	194_G	1.228	0.99
435_Q	438_Y	1.228	0.99
16_L	48_I	1.226	0.99
270_A	274_A	1.221	0.99
292_A	295_H	1.221	0.99
48_I	64_F	1.220	0.99
359_I	363_S	1.218	0.99
354_S	449_A	1.216	0.99
241_A	278_I	1.215	0.99
361_I	454_I	1.214	0.99
397_F	463_R	1.208	0.99
346_A	442_F	1.207	0.99
412_L	445_A	1.200	0.99
178_S	188_I	1.197	0.99
258_Y	262_V	1.190	0.99
454_I	458_S	1.187	0.99
142_N	153_L	1.185	0.99
40_P	62_G	1.181	0.99
408_L	448_I	1.178	0.99
163_I	271_V	1.178	0.99
358_G	458_S	1.170	0.99
180_V	187_P	1.163	0.99
23_I	83_T	1.162	0.99
175_I	232_V	1.158	0.99
248_R	251_R	1.153	0.99
306_A	414_G	1.152	0.99
185_G	242_L	1.150	0.99
9_D	53_M	1.147	0.99
10_I	82_S	1.145	0.99
289_V	316_L	1.144	0.99
14_I	23_I	1.144	0.99
233_I	237_L	1.136	0.99
115_F	232_V	1.133	0.98
397_F	461_Y	1.132	0.98
125_G	167_I	1.127	0.98
249_L	262_V	1.127	0.98
165_E	169_F	1.125	0.98
404_I	456_L	1.122	0.98
347_L	413_C	1.122	0.98
376_A	380_W	1.121	0.98
12_R	47_E	1.117	0.98
48_I	54_V	1.116	0.98
79_L	82_S	1.114	0.98
362_S	462_Q	1.110	0.98
241_A	270_A	1.103	0.98
180_V	190_G	1.100	0.98
179_A	236_L	1.099	0.98
361_I	457_T	1.094	0.98
303_P	415_L	1.092	0.98
184_G	247_T	1.092	0.98
68_I	75_Y	1.086	0.98
79_L	83_T	1.083	0.98
193_L	235_A	1.073	0.98
277_L	281_F	1.072	0.98
401_C	457_T	1.071	0.98
388_M	402_A	1.069	0.98
180_V	185_G	1.062	0.98
186_T	246_E	1.055	0.98
20_R	83_T	1.049	0.97
239_G	243_G	1.046	0.97
194_G	235_A	1.043	0.97
51_L	54_V	1.041	0.97
128_I	164_G	1.035	0.97
132_R	157_Y	1.033	0.97
340_P	343_P	1.031	0.97
448_I	452_I	1.027	0.97
8_T	11_D	1.026	0.97
166_A	195_V	1.024	0.97
440_Q	443_A	1.018	0.97
118_L	178_S	1.018	0.97
351_A	402_A	1.017	0.97
405_G	409_A	1.016	0.97
354_S	358_G	1.014	0.97
30_I	383_V	1.010	0.97
118_L	171_L	1.008	0.97
409_A	449_A	1.007	0.97
183_M	240_L	1.007	0.97
243_G	247_T	1.004	0.97
409_A	448_I	1.001	0.97
196_T	271_V	0.999	0.97
71_N	74_D	0.998	0.97
285_I	288_G	0.997	0.97
392_N	398_P	0.988	0.96
294_R	298_T	0.984	0.96
293_V	340_P	0.983	0.96
357_I	361_I	0.983	0.96
307_A	408_L	0.982	0.96
170_Y	200_P	0.980	0.96
110_H	114_I	0.980	0.96
374_P	378_S	0.978	0.96
13_L	51_L	0.978	0.96
355_A	392_N	0.974	0.96
368_E	391_I	0.972	0.96
346_A	430_G	0.972	0.96
282_G	286_G	0.971	0.96
313_Y	344_L	0.971	0.96
281_F	285_I	0.966	0.96
9_D	13_L	0.961	0.96
80_I	85_Q	0.960	0.96
438_Y	441_V	0.957	0.96
113_V	182_K	0.957	0.96
288_G	291_F	0.956	0.96
310_G	410_G	0.956	0.96
40_P	64_F	0.955	0.96
71_N	255_D	0.954	0.96
77_Q	81_A	0.954	0.96
73_G	77_Q	0.953	0.96
57_C	64_F	0.951	0.96
24_A	36_V	0.950	0.96
359_I	372_S	0.948	0.95
15_E	47_E	0.948	0.95
156_I	159_F	0.936	0.95
185_G	190_G	0.933	0.95
355_A	402_A	0.933	0.95
316_L	325_T	0.931	0.95
193_L	270_A	0.931	0.95
205_A	216_W	0.931	0.95
368_E	464_K	0.929	0.95
10_I	78_A	0.928	0.95
179_A	183_M	0.927	0.95
398_P	401_C	0.924	0.95
413_C	418_V	0.922	0.95
350_I	353_G	0.911	0.94
174_G	192_V	0.909	0.94
59_T	64_F	0.903	0.94
436_P	439_W	0.903	0.94
245_I	249_L	0.901	0.94
354_S	380_W	0.900	0.94
361_I	453_P	0.900	0.94
348_S	352_Q	0.900	0.94
176_C	194_G	0.899	0.94
12_R	52_P	0.896	0.94
194_G	266_S	0.893	0.94
447_A	451_I	0.890	0.94
134_V	138_L	0.890	0.94
440_Q	444_L	0.887	0.94
233_I	282_G	0.885	0.93
183_M	243_G	0.883	0.93
352_Q	402_A	0.883	0.93
45_P	57_C	0.883	0.93
359_I	391_I	0.879	0.93
176_C	235_A	0.878	0.93
237_L	278_I	0.877	0.93
351_A	355_A	0.877	0.93
12_R	16_L	0.875	0.93
90_K	97_A	0.872	0.93
355_A	398_P	0.871	0.93
365_K	464_K	0.869	0.93
100_N	106_Q	0.869	0.93
315_P	399_M	0.868	0.93
175_I	235_A	0.868	0.93
303_P	411_L	0.867	0.93
163_I	196_T	0.865	0.93
17_V	64_F	0.863	0.93
114_I	236_L	0.863	0.93
416_N	448_I	0.862	0.93
8_T	52_P	0.861	0.93
284_M	287_D	0.861	0.93
107_L	110_H	0.861	0.93
360_I	372_S	0.859	0.92
28_H	72_V	0.858	0.92
311_F	400_L	0.856	0.92
37_L	64_F	0.854	0.92
176_C	191_I	0.853	0.92
142_N	154_Q	0.851	0.92
184_G	190_G	0.847	0.92
99_H	103_W	0.847	0.92
11_D	78_A	0.844	0.92
176_C	239_G	0.843	0.92
278_I	282_G	0.842	0.92
418_V	445_A	0.840	0.92
311_F	403_M	0.838	0.91
306_A	310_G	0.835	0.91
165_E	199_S	0.830	0.91
40_P	45_P	0.828	0.91
46_K	50_Q	0.825	0.91
331_Q	335_S	0.825	0.91
424_G	433_S	0.824	0.91
255_D	258_Y	0.823	0.91
26_V	83_T	0.822	0.91
379_A	384_T	0.822	0.91
408_L	412_L	0.822	0.91
392_N	402_A	0.819	0.91
241_A	245_I	0.815	0.90
238_A	273_L	0.814	0.90
448_I	451_I	0.811	0.90
67_V	389_Y	0.810	0.90
250_K	262_V	0.807	0.90
95_K	98_R	0.807	0.90
198_V	229_Q	0.806	0.90
45_P	48_I	0.804	0.90
48_I	66_V	0.797	0.89
167_I	174_G	0.797	0.89
398_P	457_T	0.795	0.89
253_V	257_L	0.793	0.89
223_I	276_A	0.793	0.89
301_F	304_I	0.789	0.89
99_H	106_Q	0.789	0.89
446_M	449_A	0.786	0.89
49_E	394_K	0.786	0.89
325_T	329_D	0.784	0.89
174_G	195_V	0.784	0.89
38_N	42_N	0.783	0.88
450_I	453_P	0.783	0.88
132_R	164_G	0.781	0.88
11_D	20_R	0.781	0.88
363_S	464_K	0.779	0.88
306_A	344_L	0.778	0.88
442_F	446_M	0.777	0.88
21_G	38_N	0.775	0.88
96_A	99_H	0.774	0.88
431_I	443_A	0.772	0.88
174_G	191_I	0.771	0.88
14_I	17_V	0.771	0.88
319_T	389_Y	0.768	0.87
228_Y	234_P	0.767	0.87
458_S	461_Y	0.767	0.87
371_I	375_A	0.767	0.87
125_G	166_A	0.766	0.87
185_G	246_E	0.766	0.87
347_L	406_S	0.764	0.87
235_A	239_G	0.762	0.87
173_V	194_G	0.762	0.87
41_A	44_R	0.761	0.87
273_L	278_I	0.759	0.87
15_E	44_R	0.758	0.87
13_L	16_L	0.755	0.87
47_E	51_L	0.754	0.87
352_Q	387_A	0.753	0.86
416_N	444_L	0.752	0.86
74_D	255_D	0.749	0.86
43_A	57_C	0.749	0.86
81_A	84_G	0.748	0.86
49_E	57_C	0.748	0.86
352_Q	355_A	0.742	0.86
391_I	395_Y	0.740	0.85
177_W	192_V	0.740	0.85
43_A	64_F	0.738	0.85
254_P	257_L	0.738	0.85
80_I	83_T	0.736	0.85
384_T	387_A	0.736	0.85
99_H	102_K	0.736	0.85
17_V	23_I	0.734	0.85
412_L	415_L	0.731	0.85
317_V	348_S	0.730	0.85
192_V	196_T	0.730	0.85
245_I	266_S	0.729	0.85
347_L	409_A	0.729	0.85
362_S	458_S	0.726	0.84
360_I	369_R	0.724	0.84
303_P	307_A	0.723	0.84
109_S	113_V	0.721	0.84
379_A	387_A	0.720	0.84
166_A	196_T	0.719	0.84
110_H	240_L	0.719	0.84
449_A	453_P	0.716	0.84
21_G	42_N	0.714	0.83
13_L	17_V	0.711	0.83
98_R	106_Q	0.711	0.83
307_A	310_G	0.709	0.83
77_Q	80_I	0.709	0.83
49_E	56_G	0.707	0.83
302_A	305_G	0.707	0.83
400_L	403_M	0.706	0.83
80_I	84_G	0.704	0.83
312_L	403_M	0.704	0.83
359_I	398_P	0.704	0.83
314_A	388_M	0.701	0.82
134_V	140_M	0.701	0.82
266_S	270_A	0.700	0.82
352_Q	379_A	0.699	0.82
309_F	316_L	0.698	0.82
104_H	107_L	0.697	0.82
154_Q	158_D	0.697	0.82
9_D	68_I	0.696	0.82
218_F	276_A	0.695	0.82
158_D	161_W	0.691	0.81
257_L	381_L	0.691	0.81
357_I	454_I	0.690	0.81
166_A	199_S	0.688	0.81
253_V	265_C	0.688	0.81
9_D	12_R	0.688	0.81
351_A	405_G	0.687	0.81
418_V	441_V	0.686	0.81
203_M	207_L	0.684	0.81
309_F	327_A	0.682	0.81
9_D	75_Y	0.681	0.80
359_I	368_E	0.679	0.80
16_L	46_K	0.679	0.80
409_A	445_A	0.679	0.80
30_I	426_G	0.678	0.80
358_G	457_T	0.678	0.80
29_C	32_R	0.678	0.80
253_V	262_V	0.677	0.80
189_L	242_L	0.675	0.80
42_N	50_Q	0.674	0.80
14_I	20_R	0.673	0.80
291_F	295_H	0.671	0.79
108_I	393_L	0.671	0.79
177_W	181_K	0.670	0.79
202_L	206_Y	0.670	0.79
397_F	462_Q	0.669	0.79
134_V	137_D	0.668	0.79
38_N	85_Q	0.666	0.79
314_A	348_S	0.665	0.79
405_G	408_L	0.665	0.79
162_L	199_S	0.664	0.79
350_I	427_G	0.663	0.79
446_M	450_I	0.663	0.79
369_R	373_V	0.663	0.79
35_F	64_F	0.659	0.78
114_I	183_M	0.656	0.78
291_F	294_R	0.655	0.78
405_G	456_L	0.654	0.78
27_S	62_G	0.653	0.78
136_G	157_Y	0.652	0.77
402_A	452_I	0.650	0.77
184_G	246_E	0.650	0.77
314_A	399_M	0.648	0.77
295_H	302_A	0.648	0.77
168_F	171_L	0.647	0.77
127_L	130_G	0.647	0.77
20_R	85_Q	0.644	0.77
89_D	94_K	0.644	0.77
460_I	464_K	0.641	0.76
10_I	81_A	0.640	0.76
315_P	319_T	0.639	0.76
376_A	379_A	0.639	0.76
33_L	68_I	0.638	0.76
352_Q	384_T	0.637	0.76
79_L	84_G	0.637	0.76
246_E	250_K	0.635	0.76
410_G	414_G	0.633	0.75
138_L	141_S	0.630	0.75
458_S	462_Q	0.629	0.75
397_F	464_K	0.627	0.75
126_G	130_G	0.627	0.75
394_K	398_P	0.625	0.74
312_L	315_P	0.625	0.74
380_W	428_L	0.625	0.74
190_G	239_G	0.625	0.74
37_L	59_T	0.624	0.74
16_L	43_A	0.624	0.74
16_L	50_Q	0.623	0.74
102_K	105_E	0.623	0.74
246_E	262_V	0.623	0.74
241_A	244_V	0.623	0.74
29_C	34_R	0.622	0.74
98_R	101_M	0.621	0.74
169_F	229_Q	0.621	0.74
453_P	461_Y	0.620	0.74
422_G	433_S	0.618	0.74
392_N	399_M	0.618	0.74
401_C	455_V	0.616	0.73
362_S	464_K	0.615	0.73
426_G	430_G	0.614	0.73
408_L	411_L	0.614	0.73
283_R	287_D	0.613	0.73
269_L	272_F	0.613	0.73
153_L	158_D	0.613	0.73
356_V	360_I	0.612	0.73
314_A	352_Q	0.611	0.73
286_G	321_V	0.611	0.73
290_A	325_T	0.610	0.73
380_W	450_I	0.609	0.73
372_S	376_A	0.608	0.72
228_Y	286_G	0.608	0.72
273_L	277_L	0.608	0.72
77_Q	87_Q	0.606	0.72
114_I	179_A	0.606	0.72
317_V	352_Q	0.606	0.72
135_I	141_S	0.604	0.72
129_L	169_F	0.602	0.72
115_F	327_A	0.600	0.71
239_G	242_L	0.598	0.71
119_L	382_G	0.598	0.71
9_D	16_L	0.597	0.71
125_G	171_L	0.596	0.71
56_G	319_T	0.596	0.71
10_I	83_T	0.593	0.71
155_T	217_D	0.592	0.70
175_I	179_A	0.591	0.70
350_I	450_I	0.591	0.70
341_V	345_I	0.591	0.70
401_C	404_I	0.590	0.70
417_G	437_S	0.589	0.70
120_P	123_I	0.587	0.70
401_C	459_F	0.587	0.70
80_I	87_Q	0.586	0.70
9_D	48_I	0.585	0.70
217_D	220_M	0.585	0.70
121_A	192_V	0.584	0.69
311_F	314_A	0.584	0.69
441_V	448_I	0.584	0.69
43_A	66_V	0.583	0.69
163_I	270_A	0.582	0.69
133_N	161_W	0.581	0.69
102_K	106_Q	0.580	0.69
42_N	48_I	0.580	0.69
447_A	455_V	0.579	0.69
233_I	318_I	0.579	0.69
310_G	407_G	0.579	0.69
128_I	264_V	0.576	0.68
309_F	325_T	0.576	0.68
130_G	306_A	0.575	0.68
21_G	47_E	0.575	0.68
330_L	334_Q	0.575	0.68
431_I	446_M	0.574	0.68
425_V	433_S	0.574	0.68
349_N	402_A	0.574	0.68
406_S	410_G	0.573	0.68
238_A	270_A	0.572	0.68
211_Q	214_E	0.572	0.68
156_I	218_F	0.571	0.68
129_L	199_S	0.571	0.68
228_Y	279_G	0.571	0.68
399_M	402_A	0.571	0.68
348_S	409_A	0.570	0.68
224_A	283_R	0.568	0.67
355_A	359_I	0.568	0.67
349_N	376_A	0.568	0.67
12_R	54_V	0.567	0.67
11_D	23_I	0.567	0.67
169_F	200_P	0.563	0.67
365_K	465_Y	0.563	0.67
330_L	423_I	0.563	0.67
349_N	384_T	0.562	0.66
42_N	66_V	0.562	0.66
49_E	55_K	0.561	0.66
186_T	250_K	0.560	0.66
356_V	392_N	0.560	0.66
353_G	450_I	0.558	0.66
309_F	344_L	0.558	0.66
348_S	406_S	0.558	0.66
40_P	43_A	0.556	0.66
461_Y	464_K	0.556	0.66
350_I	446_M	0.556	0.66
292_A	296_L	0.555	0.66
418_V	439_W	0.555	0.66
347_L	449_A	0.555	0.66
324_T	327_A	0.553	0.65
194_G	242_L	0.553	0.65
161_W	165_E	0.552	0.65
361_I	458_S	0.549	0.65
404_I	407_G	0.549	0.65
215_V	224_A	0.549	0.65
185_G	243_G	0.549	0.65
27_S	66_V	0.546	0.64
158_D	162_L	0.545	0.64
119_L	123_I	0.545	0.64
152_S	156_I	0.544	0.64
40_P	99_H	0.543	0.64
84_G	88_V	0.543	0.64
42_N	90_K	0.543	0.64
181_K	184_G	0.543	0.64
68_I	71_N	0.542	0.64
185_G	266_S	0.542	0.64
249_L	266_S	0.541	0.64
156_I	219_G	0.540	0.63
130_G	399_M	0.540	0.63
114_I	130_G	0.540	0.63
142_N	152_S	0.539	0.63
88_V	101_M	0.538	0.63
202_L	275_H	0.537	0.63
88_V	97_A	0.536	0.63
74_D	78_A	0.534	0.63
166_A	192_V	0.534	0.63
251_R	364_R	0.533	0.62
259_L	262_V	0.532	0.62
155_T	216_W	0.532	0.62
30_I	259_L	0.532	0.62
13_L	75_Y	0.532	0.62
348_S	384_T	0.532	0.62
309_F	345_I	0.531	0.62
23_I	80_I	0.531	0.62
349_N	387_A	0.531	0.62
27_S	30_I	0.529	0.62
36_V	62_G	0.529	0.62
55_K	68_I	0.529	0.62
362_S	368_E	0.528	0.62
362_S	397_F	0.528	0.62
264_V	267_L	0.527	0.62
204_N	207_L	0.526	0.61
20_R	82_S	0.526	0.61
67_V	319_T	0.525	0.61
86_A	451_I	0.524	0.61
41_A	47_E	0.524	0.61
80_I	88_V	0.523	0.61
355_A	401_C	0.523	0.61
398_P	402_A	0.522	0.61
33_L	72_V	0.521	0.61
359_I	395_Y	0.520	0.61
249_L	252_I	0.519	0.60
363_S	366_H	0.518	0.60
210_Q	214_E	0.518	0.60
20_R	80_I	0.516	0.60
380_W	429_P	0.516	0.60
353_G	376_A	0.515	0.60
95_K	99_H	0.515	0.60
233_I	406_S	0.515	0.60
184_G	239_G	0.514	0.60
26_V	85_Q	0.514	0.60
368_E	462_Q	0.513	0.60
429_P	432_L	0.512	0.59
365_K	369_R	0.512	0.59
10_I	75_Y	0.512	0.59
435_Q	439_W	0.511	0.59
85_Q	251_R	0.511	0.59
191_I	194_G	0.510	0.59
281_F	284_M	0.510	0.59
357_I	360_I	0.510	0.59
21_G	41_A	0.509	0.59
187_P	239_G	0.509	0.59
129_L	168_F	0.508	0.59
55_K	70_T	0.507	0.59
180_V	242_L	0.506	0.58
9_D	71_N	0.505	0.58
359_I	392_N	0.505	0.58
326_L	330_L	0.505	0.58
339_T	343_P	0.504	0.58
314_A	384_T	0.503	0.58
27_S	63_Q	0.503	0.58
104_H	108_I	0.502	0.58
122_L	323_Q	0.501	0.58
126_G	423_I	0.501	0.58
12_R	81_A	0.501	0.58
53_M	75_Y	0.500	0.58
460_I	465_Y	0.500	0.58

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3qnqA	2	0.7928	100	0.659	Contact Map
3ipjA	1	0.1987	100	0.797	Contact Map
3bp3A	1	0.1712	100	0.802	Contact Map
1ibaA	1	0.1649	100	0.802	Contact Map
4n8nA	1	0.1015	40.9	0.974	Contact Map
4nv5A	1	0.1353	28.6	0.976	Contact Map
2h8eA	2	0.1882	27	0.977	Contact Map
4qn1A	1	0.1691	24.8	0.977	Contact Map
3q9vA	1	0.1226	24.6	0.977	Contact Map
2hwvA	1	0.129	18.1	0.979	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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