DSBD - ECOLI - GREMLIN Contacts

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DSBD - Thiol:disulfide interchange protein DsbD

UniProt:	P36655	Sequences: MAQRIFTLILLLCSTSVFAGLFDAPGRSQFVPADQAFAFDFQQNQHDLNLTWQIKDGYYLYRKQIRITPEHAKIADVQLPQGVWHEDEFYGKSEIYRDRLTLPVTINQASAGATLTVTYQGCADAGFCYPPETKTVPLSEVVANNAAPQPVSVPQQEQPTAQLPFSALWALLIGIGIAFTPCVLPMYPLISGIVLGGKQRLSTARALLLTFIYVQGMALTYTALGLVVAAAGLQFQAALQHPYVLIGLAIVFTLLAMSMFGLFTLQLPSSLQTRLTLMSNRQQGGSPGGVFVMGAIAGLICSPCTTAPLSAILLYIAQSGNMWLGGGTLYLYALGMGLPLMLITVFGNRLLPKSGPWMEQVKTAFGFVILALPVFLLERVIGDVWGLRLWSALGVAFFGWAFITSLQAKRGWMRIVQIILLAAALVSVRPLQDWAFGATHTAQTQTHLNFTQIKTVDELNQALVEAKGKPVMLDLYADWCVACKEFEKYTFSDPQVQKALADTVLLQANVTANDAQDVALLKHLNVLGLPTILFFDGQGQEHPQARVTGFMDAETFSAHLRDRQP	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG12178
Length:	565 (527)
Sequences:	2096 (1580)
Seq/√Len:	68.8

ECOLI - DSBD

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
171_L	338_L	5.481	1.00
536_D	540_Q	4.198	1.00
168_L	172_L	4.127	1.00
172_L	176_G	4.038	1.00
75_A	105_T	4.022	1.00
222_T	330_Y	3.749	1.00
469_K	504_V	3.721	1.00
83_V	97_R	3.640	1.00
256_A	370_L	3.609	1.00
86_E	92_K	3.357	1.00
260_F	370_L	3.302	1.00
59_Y	85_H	3.255	1.00
450_F	453_I	3.208	1.00
116_T	135_T	3.200	1.00
167_A	331_L	3.031	1.00
256_A	260_F	2.995	1.00
82_G	94_E	2.860	1.00
261_G	264_T	2.849	1.00
458_E	462_A	2.835	1.00
62_R	82_G	2.819	1.00
460_N	523_H	2.781	1.00
552_D	555_T	2.767	1.00
452_Q	507_Q	2.654	1.00
86_E	91_G	2.615	1.00
207_L	345_V	2.570	1.00
243_Y	246_I	2.570	1.00
554_E	558_A	2.558	1.00
430_P	434_W	2.547	1.00
255_L	369_I	2.539	1.00
212_I	287_P	2.507	1.00
73_K	107_N	2.501	1.00
32_P	35_Q	2.408	1.00
30_F	127_F	2.377	1.00
367_F	397_F	2.351	1.00
484_K	487_E	2.328	1.00
180_T	183_V	2.314	1.00
222_T	333_A	2.286	1.00
214_V	337_G	2.274	1.00
215_Q	330_Y	2.266	1.00
260_F	366_G	2.263	1.00
429_R	433_D	2.260	1.00
62_R	94_E	2.234	1.00
216_G	291_F	2.221	1.00
51_T	101_T	2.220	1.00
54_I	99_R	2.216	1.00
84_W	92_K	2.216	1.00
451_T	506_L	2.209	1.00
31_V	37_F	2.175	1.00
451_T	458_E	2.084	1.00
21_L	24_A	2.062	1.00
203_T	206_A	2.057	1.00
114_T	137_P	2.044	1.00
472_M	534_F	2.015	1.00
229_A	317_A	1.977	1.00
48_L	104_V	1.934	1.00
30_F	125_A	1.903	1.00
496_V	557_S	1.901	1.00
453_I	459_L	1.878	1.00
210_T	344_T	1.876	1.00
490_T	550_F	1.875	1.00
39_F	50_L	1.871	1.00
67_I	77_V	1.856	1.00
84_W	94_E	1.853	1.00
254_L	263_F	1.851	1.00
495_Q	554_E	1.837	1.00
524_L	535_F	1.832	1.00
451_T	462_A	1.825	1.00
257_M	262_L	1.825	1.00
114_T	135_T	1.817	1.00
53_Q	99_R	1.806	1.00
273_T	276_T	1.802	1.00
97_R	124_D	1.794	1.00
167_A	327_G	1.793	1.00
31_V	36_A	1.793	1.00
264_T	468_G	1.790	1.00
47_D	105_T	1.787	1.00
475_L	508_A	1.786	1.00
169_W	173_I	1.771	1.00
246_I	250_I	1.757	1.00
469_K	502_D	1.755	1.00
171_L	334_L	1.747	1.00
249_A	377_L	1.734	1.00
39_F	136_V	1.733	1.00
154_P	158_Q	1.730	1.00
220_T	295_A	1.719	1.00
485_E	489_Y	1.718	1.00
417_Q	420_L	1.718	1.00
77_V	102_L	1.698	1.00
417_Q	427_S	1.694	1.00
536_D	539_G	1.692	1.00
204_A	208_L	1.691	1.00
80_P	100_L	1.687	1.00
177_I	332_Y	1.678	0.99
77_V	104_V	1.668	0.99
499_A	557_S	1.655	0.99
214_V	341_M	1.652	0.99
420_L	424_A	1.650	0.99
508_A	520_L	1.640	0.99
35_Q	38_A	1.630	0.99
361_V	365_F	1.627	0.99
456_V	460_N	1.619	0.99
286_S	289_G	1.617	0.99
229_A	322_M	1.610	0.99
450_F	505_L	1.605	0.99
85_H	97_R	1.598	0.99
164_P	168_L	1.591	0.99
229_A	232_G	1.560	0.99
258_S	263_F	1.551	0.99
526_V	531_T	1.547	0.99
494_P	498_K	1.543	0.99
49_N	103_P	1.534	0.99
485_E	550_F	1.531	0.99
31_V	55_K	1.528	0.99
266_Q	272_Q	1.521	0.99
389_L	400_W	1.508	0.99
87_D	90_Y	1.506	0.99
120_Q	129_Y	1.489	0.99
470_P	502_D	1.486	0.99
170_A	312_I	1.478	0.99
207_L	211_F	1.468	0.99
18_F	21_L	1.463	0.99
424_A	427_S	1.463	0.99
269_S	273_T	1.463	0.99
253_T	370_L	1.457	0.99
510_V	517_D	1.443	0.98
59_Y	97_R	1.441	0.98
122_C	128_C	1.438	0.98
212_I	216_G	1.426	0.98
253_T	373_P	1.420	0.98
44_N	47_D	1.417	0.98
270_S	273_T	1.413	0.98
396_A	418_I	1.406	0.98
19_A	23_D	1.390	0.98
474_D	507_Q	1.388	0.98
551_M	555_T	1.386	0.98
231_A	234_Q	1.379	0.98
486_F	551_M	1.373	0.98
387_L	391_S	1.367	0.98
69_P	72_A	1.367	0.98
547_V	551_M	1.366	0.98
539_G	542_H	1.366	0.98
208_L	287_P	1.362	0.98
267_L	271_L	1.361	0.98
88_E	91_G	1.358	0.98
229_A	326_G	1.355	0.98
471_V	504_V	1.354	0.98
65_I	100_L	1.352	0.98
229_A	325_G	1.345	0.98
15_T	20_G	1.341	0.97
456_V	523_H	1.338	0.97
428_V	432_Q	1.332	0.97
478_D	484_K	1.329	0.97
295_A	299_L	1.327	0.97
359_E	362_K	1.318	0.97
405_S	417_Q	1.313	0.97
429_R	432_Q	1.312	0.97
243_Y	247_G	1.311	0.97
306_T	347_G	1.310	0.97
49_N	101_T	1.309	0.97
429_R	434_W	1.304	0.97
67_I	104_V	1.304	0.97
470_P	537_G	1.303	0.97
556_F	559_H	1.302	0.97
475_L	520_L	1.297	0.97
112_G	137_P	1.291	0.97
17_V	20_G	1.287	0.97
374_V	389_L	1.285	0.97
458_E	461_Q	1.282	0.97
366_G	370_L	1.277	0.97
241_H	246_I	1.273	0.97
423_A	427_S	1.270	0.97
235_F	238_A	1.268	0.96
216_G	234_Q	1.261	0.96
498_K	501_A	1.261	0.96
497_Q	501_A	1.259	0.96
455_T	458_E	1.257	0.96
169_W	176_G	1.255	0.96
244_V	248_L	1.252	0.96
236_Q	379_R	1.248	0.96
30_F	33_A	1.245	0.96
455_T	506_L	1.243	0.96
428_V	433_D	1.243	0.96
400_W	403_I	1.243	0.96
72_A	75_A	1.241	0.96
380_V	384_V	1.238	0.96
181_P	184_L	1.234	0.96
551_M	559_H	1.234	0.96
228_V	302_S	1.232	0.96
123_A	129_Y	1.223	0.96
166_S	328_T	1.220	0.96
398_F	402_F	1.214	0.95
120_Q	130_P	1.206	0.95
298_G	302_S	1.206	0.95
52_W	60_L	1.205	0.95
34_D	119_Y	1.196	0.95
31_V	35_Q	1.184	0.95
209_L	290_V	1.184	0.95
20_G	23_D	1.183	0.95
121_G	129_Y	1.179	0.95
211_F	215_Q	1.176	0.95
396_A	400_W	1.175	0.95
69_P	74_I	1.173	0.95
546_R	549_G	1.169	0.94
56_D	98_D	1.169	0.94
22_F	25_P	1.164	0.94
482_A	485_E	1.153	0.94
437_G	440_H	1.153	0.94
239_L	244_V	1.150	0.94
453_I	456_V	1.146	0.94
515_A	519_A	1.142	0.94
33_A	36_A	1.142	0.94
100_L	103_P	1.139	0.94
333_A	348_N	1.138	0.94
264_T	362_K	1.132	0.93
173_I	176_G	1.116	0.93
184_L	333_A	1.112	0.93
47_D	103_P	1.112	0.93
239_L	302_S	1.111	0.93
306_T	317_A	1.110	0.93
452_Q	456_V	1.104	0.93
155_Q	159_P	1.104	0.93
428_V	434_W	1.103	0.93
403_I	417_Q	1.103	0.93
270_S	274_R	1.097	0.92
255_L	263_F	1.097	0.92
112_G	139_S	1.095	0.92
51_T	99_R	1.095	0.92
309_L	325_G	1.095	0.92
487_E	507_Q	1.094	0.92
552_D	556_F	1.090	0.92
521_L	526_V	1.087	0.92
397_F	400_W	1.086	0.92
191_S	343_I	1.077	0.92
371_A	390_W	1.076	0.92
499_A	503_T	1.074	0.92
30_F	37_F	1.073	0.91
520_L	524_L	1.067	0.91
19_A	22_F	1.066	0.91
346_F	350_L	1.063	0.91
374_V	393_L	1.059	0.91
327_G	331_L	1.057	0.91
548_T	551_M	1.052	0.91
548_T	555_T	1.045	0.90
30_F	35_Q	1.044	0.90
462_A	506_L	1.035	0.90
402_F	417_Q	1.034	0.90
219_L	291_F	1.030	0.90
16_S	19_A	1.024	0.89
508_A	517_D	1.020	0.89
489_Y	553_A	1.013	0.89
32_P	37_F	1.012	0.89
534_F	559_H	1.009	0.89
403_I	406_L	1.007	0.89
516_Q	519_A	1.005	0.89
120_Q	131_P	1.003	0.88
30_F	123_A	1.000	0.88
274_R	278_M	1.000	0.88
429_R	439_T	1.000	0.88
14_S	19_A	0.999	0.88
432_Q	436_F	0.996	0.88
537_G	540_Q	0.989	0.88
354_S	358_M	0.987	0.88
255_L	490_T	0.986	0.88
436_F	440_H	0.986	0.88
298_G	336_M	0.985	0.88
85_H	95_I	0.985	0.88
474_D	505_L	0.983	0.87
92_K	120_Q	0.983	0.87
187_Y	224_L	0.980	0.87
221_Y	298_G	0.980	0.87
251_V	254_L	0.976	0.87
301_C	305_T	0.974	0.87
503_T	534_F	0.974	0.87
50_L	136_V	0.972	0.87
16_S	23_D	0.970	0.87
493_D	496_V	0.969	0.87
25_P	28_S	0.966	0.87
305_T	527_L	0.964	0.86
305_T	310_S	0.963	0.86
370_L	393_L	0.963	0.86
305_T	529_L	0.958	0.86
555_T	558_A	0.956	0.86
467_K	470_P	0.955	0.86
252_F	369_I	0.953	0.86
30_F	36_A	0.947	0.85
188_P	192_G	0.946	0.85
284_G	289_G	0.942	0.85
79_L	82_G	0.941	0.85
225_G	325_G	0.935	0.85
457_D	460_N	0.931	0.84
191_S	194_V	0.931	0.84
302_S	305_T	0.924	0.84
68_T	72_A	0.922	0.84
171_L	207_L	0.915	0.83
15_T	18_F	0.913	0.83
292_V	295_A	0.910	0.83
453_I	506_L	0.909	0.83
227_V	230_A	0.908	0.83
234_Q	306_T	0.904	0.83
31_V	129_Y	0.903	0.83
240_Q	479_W	0.901	0.82
218_A	330_Y	0.901	0.82
214_V	334_L	0.899	0.82
225_G	232_G	0.898	0.82
495_Q	557_S	0.898	0.82
50_L	117_V	0.897	0.82
311_A	317_A	0.897	0.82
96_Y	117_V	0.896	0.82
116_T	133_T	0.893	0.82
476_Y	507_Q	0.886	0.81
253_T	257_M	0.884	0.81
58_Y	82_G	0.883	0.81
377_L	380_V	0.882	0.81
33_A	37_F	0.881	0.81
235_F	298_G	0.880	0.81
184_L	195_L	0.878	0.81
13_C	21_L	0.874	0.80
460_N	463_L	0.873	0.80
455_T	459_L	0.873	0.80
263_F	275_L	0.871	0.80
32_P	39_F	0.871	0.80
491_F	556_F	0.870	0.80
75_A	78_Q	0.866	0.80
395_V	424_A	0.866	0.80
165_F	169_W	0.864	0.80
20_G	24_A	0.864	0.80
402_F	405_S	0.862	0.80
322_M	326_G	0.861	0.79
252_F	302_S	0.860	0.79
264_T	359_E	0.860	0.79
198_K	201_L	0.858	0.79
59_Y	65_I	0.857	0.79
415_I	423_A	0.856	0.79
192_G	195_L	0.853	0.79
79_L	96_Y	0.852	0.79
218_A	326_G	0.852	0.79
492_S	557_S	0.851	0.79
381_I	384_V	0.850	0.79
119_Y	132_E	0.849	0.79
251_V	324_L	0.846	0.78
115_L	135_T	0.845	0.78
52_W	102_L	0.844	0.78
20_G	27_R	0.843	0.78
453_I	473_L	0.841	0.78
260_F	309_L	0.840	0.78
115_L	136_V	0.838	0.78
443_Q	515_A	0.837	0.78
275_L	292_V	0.834	0.77
490_T	496_V	0.834	0.77
237_A	241_H	0.832	0.77
182_C	304_C	0.830	0.77
345_V	348_N	0.829	0.77
341_M	345_V	0.828	0.77
500_L	503_T	0.826	0.77
31_V	58_Y	0.825	0.76
117_V	140_E	0.825	0.76
542_H	545_A	0.820	0.76
216_G	379_R	0.817	0.76
38_A	53_Q	0.817	0.76
453_I	458_E	0.817	0.76
75_A	107_N	0.815	0.76
203_T	349_R	0.814	0.76
343_I	481_V	0.811	0.75
21_L	25_P	0.811	0.75
175_I	254_L	0.809	0.75
363_T	367_F	0.809	0.75
18_F	24_A	0.809	0.75
541_E	546_R	0.808	0.75
302_S	332_Y	0.808	0.75
17_V	21_L	0.804	0.75
170_A	326_G	0.804	0.75
205_R	208_L	0.804	0.75
432_Q	435_A	0.803	0.75
68_T	137_P	0.802	0.74
48_L	115_L	0.798	0.74
232_G	325_G	0.797	0.74
78_Q	105_T	0.796	0.74
57_G	123_A	0.796	0.74
307_A	311_A	0.795	0.74
400_W	405_S	0.790	0.73
60_L	117_V	0.789	0.73
239_L	325_G	0.786	0.73
489_Y	492_S	0.786	0.73
448_L	505_L	0.786	0.73
461_Q	467_K	0.780	0.72
45_Q	107_N	0.778	0.72
77_V	105_T	0.777	0.72
547_V	552_D	0.777	0.72
399_G	403_I	0.776	0.72
17_V	24_A	0.776	0.72
212_I	290_V	0.774	0.72
374_V	386_G	0.772	0.72
505_L	520_L	0.770	0.71
320_G	324_L	0.766	0.71
417_Q	421_L	0.765	0.71
59_Y	121_G	0.765	0.71
276_T	279_S	0.765	0.71
506_L	517_D	0.765	0.71
459_L	463_L	0.765	0.71
456_V	524_L	0.764	0.71
456_V	462_A	0.763	0.71
435_A	440_H	0.760	0.70
222_T	326_G	0.759	0.70
306_T	528_G	0.758	0.70
18_F	22_F	0.756	0.70
58_Y	307_A	0.755	0.70
369_I	372_L	0.755	0.70
15_T	23_D	0.754	0.70
249_A	373_P	0.750	0.69
275_L	278_M	0.750	0.69
266_Q	302_S	0.749	0.69
431_L	440_H	0.749	0.69
266_Q	269_S	0.748	0.69
217_M	336_M	0.747	0.69
399_G	404_T	0.746	0.69
367_F	400_W	0.746	0.69
517_D	521_L	0.744	0.69
288_G	292_V	0.743	0.69
171_L	175_I	0.743	0.69
547_V	557_S	0.743	0.69
85_H	90_Y	0.742	0.69
411_G	414_R	0.741	0.68
213_Y	290_V	0.740	0.68
470_P	503_T	0.739	0.68
31_V	121_G	0.739	0.68
234_Q	379_R	0.739	0.68
394_G	427_S	0.737	0.68
235_F	301_C	0.736	0.68
310_S	529_L	0.732	0.68
65_I	79_L	0.731	0.67
301_C	529_L	0.731	0.67
23_D	26_G	0.731	0.67
189_L	297_A	0.731	0.67
59_Y	67_I	0.730	0.67
300_I	305_T	0.729	0.67
298_G	305_T	0.728	0.67
440_H	445_Q	0.727	0.67
444_T	447_H	0.725	0.67
31_V	38_A	0.724	0.67
242_P	250_I	0.724	0.67
190_I	210_T	0.723	0.67
87_D	93_S	0.723	0.67
308_P	329_L	0.723	0.67
476_Y	482_A	0.721	0.66
217_M	245_L	0.718	0.66
305_T	309_L	0.716	0.66
163_L	327_G	0.714	0.66
165_F	168_L	0.712	0.65
386_G	389_L	0.712	0.65
547_V	550_F	0.712	0.65
493_D	553_A	0.712	0.65
407_Q	411_G	0.709	0.65
65_I	120_Q	0.709	0.65
60_L	65_I	0.709	0.65
176_G	361_V	0.708	0.65
188_P	370_L	0.708	0.65
298_G	312_I	0.707	0.65
154_P	160_T	0.707	0.65
187_Y	475_L	0.707	0.65
177_I	312_I	0.706	0.65
165_F	172_L	0.705	0.65
17_V	25_P	0.704	0.65
513_N	517_D	0.703	0.64
82_G	89_F	0.700	0.64
170_A	297_A	0.699	0.64
279_S	343_I	0.698	0.64
414_R	417_Q	0.698	0.64
27_R	30_F	0.696	0.64
412_W	416_V	0.694	0.63
532_I	547_V	0.694	0.63
67_I	102_L	0.694	0.63
285_G	290_V	0.693	0.63
190_I	354_S	0.692	0.63
231_A	317_A	0.691	0.63
14_S	20_G	0.688	0.63
396_A	417_Q	0.685	0.62
30_F	55_K	0.685	0.62
430_P	433_D	0.684	0.62
193_I	293_M	0.683	0.62
231_A	391_S	0.682	0.62
48_L	138_L	0.681	0.62
13_C	16_S	0.680	0.62
440_H	443_Q	0.680	0.62
59_Y	89_F	0.680	0.62
496_V	499_A	0.680	0.62
367_F	402_F	0.679	0.62
496_V	500_L	0.678	0.62
85_H	124_D	0.678	0.62
123_A	127_F	0.678	0.62
39_F	42_Q	0.677	0.61
410_R	414_R	0.674	0.61
211_F	345_V	0.673	0.61
309_L	478_D	0.672	0.61
55_K	58_Y	0.671	0.61
434_W	437_G	0.669	0.61
88_E	92_K	0.669	0.61
171_L	343_I	0.669	0.61
218_A	222_T	0.668	0.60
485_E	490_T	0.668	0.60
359_E	363_T	0.666	0.60
216_G	295_A	0.665	0.60
162_Q	292_V	0.664	0.60
32_P	38_A	0.664	0.60
536_D	542_H	0.663	0.60
58_Y	62_R	0.663	0.60
470_P	534_F	0.661	0.60
50_L	115_L	0.660	0.60
50_L	104_V	0.659	0.59
298_G	310_S	0.658	0.59
252_F	255_L	0.658	0.59
337_G	347_G	0.657	0.59
224_L	314_L	0.656	0.59
354_S	372_L	0.655	0.59
169_W	289_G	0.654	0.59
225_G	229_A	0.653	0.59
113_A	140_E	0.653	0.59
181_P	215_Q	0.652	0.59
294_G	335_G	0.650	0.58
482_A	486_F	0.650	0.58
194_V	344_T	0.650	0.58
43_Q	138_L	0.650	0.58
344_T	348_N	0.649	0.58
178_A	369_I	0.648	0.58
245_L	375_F	0.646	0.58
390_W	393_L	0.645	0.58
234_Q	291_F	0.645	0.58
209_L	213_Y	0.645	0.58
230_A	322_M	0.644	0.58
239_L	300_I	0.644	0.58
490_T	552_D	0.643	0.58
435_A	439_T	0.643	0.58
399_G	417_Q	0.641	0.57
235_F	531_T	0.641	0.57
490_T	553_A	0.640	0.57
467_K	504_V	0.640	0.57
479_W	509_N	0.640	0.57
168_L	171_L	0.640	0.57
172_L	338_L	0.639	0.57
452_Q	457_D	0.638	0.57
16_S	22_F	0.638	0.57
14_S	18_F	0.635	0.57
356_P	359_E	0.635	0.57
37_F	129_Y	0.634	0.56
499_A	502_D	0.634	0.56
465_E	533_L	0.633	0.56
250_I	514_D	0.633	0.56
41_F	138_L	0.633	0.56
60_L	95_I	0.632	0.56
52_W	117_V	0.632	0.56
360_Q	363_T	0.631	0.56
446_T	467_K	0.630	0.56
189_L	330_Y	0.630	0.56
431_L	434_W	0.629	0.56
504_V	536_D	0.627	0.56
428_V	431_L	0.627	0.56
314_L	317_A	0.627	0.56
36_A	39_F	0.627	0.56
472_M	505_L	0.626	0.56
58_Y	129_Y	0.626	0.56
15_T	19_A	0.623	0.55
295_A	332_Y	0.623	0.55
325_G	340_L	0.621	0.55
235_F	310_S	0.621	0.55
418_I	427_S	0.621	0.55
46_H	106_I	0.620	0.55
246_I	377_L	0.619	0.55
233_L	298_G	0.619	0.55
436_F	439_T	0.618	0.55
251_V	545_A	0.618	0.55
54_I	98_D	0.618	0.55
170_A	190_I	0.617	0.54
202_S	205_R	0.617	0.54
460_N	519_A	0.616	0.54
433_D	437_G	0.613	0.54
358_M	374_V	0.613	0.54
216_G	236_Q	0.612	0.54
121_G	131_P	0.612	0.54
390_W	394_G	0.612	0.54
203_T	207_L	0.612	0.54
238_A	486_F	0.610	0.54
85_H	120_Q	0.608	0.53
416_V	427_S	0.606	0.53
244_V	255_L	0.605	0.53
300_I	490_T	0.603	0.53
283_Q	419_I	0.603	0.53
33_A	38_A	0.603	0.53
259_M	362_K	0.603	0.53
220_T	378_E	0.602	0.53
473_L	535_F	0.602	0.53
302_S	306_T	0.601	0.53
77_V	381_I	0.601	0.53
465_E	468_G	0.601	0.53
220_T	298_G	0.600	0.52
236_Q	291_F	0.600	0.52
173_I	318_Q	0.599	0.52
45_Q	105_T	0.599	0.52
173_I	312_I	0.599	0.52
534_F	560_L	0.599	0.52
15_T	22_F	0.597	0.52
59_Y	87_D	0.597	0.52
60_L	120_Q	0.597	0.52
305_T	528_G	0.596	0.52
195_L	344_T	0.595	0.52
279_S	283_Q	0.595	0.52
83_V	98_D	0.594	0.52
154_P	157_E	0.594	0.52
169_W	225_G	0.593	0.52
57_G	74_I	0.591	0.51
327_G	498_K	0.591	0.51
557_S	560_L	0.590	0.51
536_D	541_E	0.589	0.51
330_Y	334_L	0.589	0.51
306_T	375_F	0.588	0.51
258_S	262_L	0.587	0.51
248_L	301_C	0.586	0.51
37_F	121_G	0.586	0.51
400_W	404_T	0.585	0.51
300_I	363_T	0.584	0.51
65_I	94_E	0.583	0.50
184_L	400_W	0.581	0.50
506_L	520_L	0.580	0.50
293_M	366_G	0.580	0.50
477_A	509_N	0.580	0.50
30_F	38_A	0.578	0.50
486_F	508_A	0.578	0.50
478_D	507_Q	0.578	0.50
225_G	314_L	0.576	0.50
306_T	550_F	0.575	0.49
407_Q	410_R	0.575	0.49
60_L	119_Y	0.573	0.49
371_A	405_S	0.572	0.49
225_G	330_Y	0.572	0.49
472_M	532_I	0.570	0.49
243_Y	248_L	0.570	0.49
210_T	532_I	0.568	0.49
303_P	310_S	0.568	0.49
82_G	129_Y	0.567	0.48
274_R	277_L	0.567	0.48
133_T	136_V	0.566	0.48
513_N	518_V	0.565	0.48
226_L	326_G	0.565	0.48
457_D	461_Q	0.564	0.48
76_D	105_T	0.564	0.48
443_Q	446_T	0.564	0.48
312_I	328_T	0.563	0.48
205_R	209_L	0.563	0.48
225_G	244_V	0.563	0.48
468_G	504_V	0.563	0.48
30_F	58_Y	0.562	0.48
272_Q	302_S	0.561	0.48
405_S	414_R	0.561	0.48
381_I	403_I	0.560	0.48
236_Q	239_L	0.559	0.48
507_Q	532_I	0.559	0.48
235_F	312_I	0.559	0.48
190_I	194_V	0.559	0.48
236_Q	314_L	0.558	0.47
417_Q	424_A	0.558	0.47
36_A	129_Y	0.557	0.47
259_M	524_L	0.557	0.47
263_F	429_R	0.557	0.47
420_L	427_S	0.557	0.47
178_A	335_G	0.556	0.47
394_G	423_A	0.555	0.47
439_T	442_A	0.555	0.47
208_L	211_F	0.554	0.47
86_E	89_F	0.553	0.47
519_A	522_K	0.553	0.47
482_A	487_E	0.553	0.47
123_A	130_P	0.553	0.47
32_P	36_A	0.553	0.47
17_V	23_D	0.553	0.47
402_F	406_L	0.552	0.47
422_A	498_K	0.552	0.47
206_A	345_V	0.550	0.46
277_L	353_K	0.550	0.46
302_S	376_L	0.549	0.46
54_I	97_R	0.548	0.46
252_F	340_L	0.547	0.46
373_P	377_L	0.547	0.46
219_L	333_A	0.546	0.46
177_I	335_G	0.545	0.46
379_R	386_G	0.545	0.46
520_L	533_L	0.544	0.46
205_R	401_A	0.544	0.46
183_V	305_T	0.544	0.46
329_L	529_L	0.544	0.46
225_G	251_V	0.544	0.46
88_E	97_R	0.543	0.46
211_F	341_M	0.543	0.46
17_V	22_F	0.543	0.46
233_L	521_L	0.543	0.46
64_Q	82_G	0.542	0.45
442_A	445_Q	0.542	0.45
356_P	417_Q	0.542	0.45
275_L	279_S	0.541	0.45
180_T	306_T	0.540	0.45
54_I	60_L	0.538	0.45
59_Y	553_A	0.538	0.45
471_V	474_D	0.537	0.45
481_V	510_V	0.536	0.45
162_Q	515_A	0.536	0.45
65_I	119_Y	0.536	0.45
173_I	231_A	0.535	0.45
213_Y	300_I	0.535	0.45
531_T	549_G	0.534	0.45
210_T	214_V	0.534	0.45
210_T	340_L	0.534	0.45
60_L	121_G	0.534	0.45
220_T	236_Q	0.534	0.45
371_A	374_V	0.533	0.44
110_S	139_S	0.533	0.44
235_F	305_T	0.532	0.44
61_Y	87_D	0.532	0.44
234_Q	305_T	0.532	0.44
450_F	507_Q	0.532	0.44
450_F	456_V	0.530	0.44
341_M	344_T	0.530	0.44
486_F	517_D	0.530	0.44
508_A	524_L	0.528	0.44
99_R	103_P	0.528	0.44
389_L	396_A	0.527	0.44
371_A	393_L	0.526	0.44
238_A	317_A	0.526	0.44
310_S	347_G	0.525	0.43
39_F	52_W	0.524	0.43
52_W	100_L	0.523	0.43
526_V	548_T	0.523	0.43
218_A	336_M	0.523	0.43
401_A	431_L	0.522	0.43
239_L	380_V	0.522	0.43
62_R	65_I	0.521	0.43
41_F	137_P	0.521	0.43
290_V	333_A	0.521	0.43
486_F	490_T	0.520	0.43
481_V	485_E	0.520	0.43
179_F	492_S	0.520	0.43
48_L	136_V	0.520	0.43
106_I	407_Q	0.520	0.43
303_P	479_W	0.519	0.43
179_F	361_V	0.519	0.43
213_Y	367_F	0.518	0.43
295_A	401_A	0.518	0.43
216_G	302_S	0.518	0.43
291_F	333_A	0.517	0.43
419_I	558_A	0.516	0.42
475_L	505_L	0.516	0.42
258_S	261_G	0.516	0.42
70_E	74_I	0.515	0.42
121_G	549_G	0.515	0.42
290_V	472_M	0.515	0.42
315_Y	320_G	0.515	0.42
272_Q	275_L	0.514	0.42
392_A	425_L	0.514	0.42
213_Y	431_L	0.514	0.42
495_Q	553_A	0.513	0.42
163_L	324_L	0.513	0.42
56_D	76_D	0.512	0.42
231_A	238_A	0.511	0.42
80_P	120_Q	0.511	0.42
52_W	119_Y	0.511	0.42
41_F	374_V	0.510	0.42
173_I	235_F	0.509	0.42
430_P	439_T	0.509	0.42
177_I	190_I	0.509	0.42
195_L	298_G	0.509	0.42
315_Y	319_S	0.506	0.41
412_W	415_I	0.506	0.41
358_M	361_V	0.506	0.41
136_V	508_A	0.505	0.41
63_K	82_G	0.505	0.41
184_L	307_A	0.505	0.41
138_L	287_P	0.504	0.41
178_A	490_T	0.504	0.41
80_P	138_L	0.504	0.41
186_M	190_I	0.504	0.41
241_H	344_T	0.504	0.41
166_S	336_M	0.504	0.41
191_S	300_I	0.504	0.41
377_L	385_W	0.503	0.41
237_A	245_L	0.503	0.41
303_P	477_A	0.503	0.41
478_D	487_E	0.502	0.41
324_L	328_T	0.502	0.41
144_N	501_A	0.501	0.41
422_A	515_A	0.501	0.41
476_Y	509_N	0.501	0.41
550_F	555_T	0.501	0.41
473_L	534_F	0.501	0.41
363_T	400_W	0.500	0.41

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2k0rA	1	0.2212	100	0.832	Contact Map
1l6pA	1	0.2142	100	0.832	Contact Map
3pfuA	1	0.2106	100	0.833	Contact Map
1jpeA	1	0.2053	100	0.835	Contact Map
2ec4A	1	0.2496	99.9	0.87	Contact Map
4nv5A	1	0.4407	99.8	0.882	Contact Map
2fwhA	1	0.2071	99.8	0.882	Contact Map
2dlxA	1	0.2336	99.8	0.884	Contact Map
3iraA	1	0.2336	99.7	0.894	Contact Map
2av4A	3	0.1982	99.6	0.899	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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