GREMLIN Database
DSBD - Thiol:disulfide interchange protein DsbD
UniProt: P36655 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG12178
Length: 565 (527)
Sequences: 2096 (1580)
Seq/√Len: 68.8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
171_L338_L5.4811.00
536_D540_Q4.1981.00
168_L172_L4.1271.00
172_L176_G4.0381.00
75_A105_T4.0221.00
222_T330_Y3.7491.00
469_K504_V3.7211.00
83_V97_R3.6401.00
256_A370_L3.6091.00
86_E92_K3.3571.00
260_F370_L3.3021.00
59_Y85_H3.2551.00
450_F453_I3.2081.00
116_T135_T3.2001.00
167_A331_L3.0311.00
256_A260_F2.9951.00
82_G94_E2.8601.00
261_G264_T2.8491.00
458_E462_A2.8351.00
62_R82_G2.8191.00
460_N523_H2.7811.00
552_D555_T2.7671.00
452_Q507_Q2.6541.00
86_E91_G2.6151.00
207_L345_V2.5701.00
243_Y246_I2.5701.00
554_E558_A2.5581.00
430_P434_W2.5471.00
255_L369_I2.5391.00
212_I287_P2.5071.00
73_K107_N2.5011.00
32_P35_Q2.4081.00
30_F127_F2.3771.00
367_F397_F2.3511.00
484_K487_E2.3281.00
180_T183_V2.3141.00
222_T333_A2.2861.00
214_V337_G2.2741.00
215_Q330_Y2.2661.00
260_F366_G2.2631.00
429_R433_D2.2601.00
62_R94_E2.2341.00
216_G291_F2.2211.00
51_T101_T2.2201.00
54_I99_R2.2161.00
84_W92_K2.2161.00
451_T506_L2.2091.00
31_V37_F2.1751.00
451_T458_E2.0841.00
21_L24_A2.0621.00
203_T206_A2.0571.00
114_T137_P2.0441.00
472_M534_F2.0151.00
229_A317_A1.9771.00
48_L104_V1.9341.00
30_F125_A1.9031.00
496_V557_S1.9011.00
453_I459_L1.8781.00
210_T344_T1.8761.00
490_T550_F1.8751.00
39_F50_L1.8711.00
67_I77_V1.8561.00
84_W94_E1.8531.00
254_L263_F1.8511.00
495_Q554_E1.8371.00
524_L535_F1.8321.00
451_T462_A1.8251.00
257_M262_L1.8251.00
114_T135_T1.8171.00
53_Q99_R1.8061.00
273_T276_T1.8021.00
97_R124_D1.7941.00
167_A327_G1.7931.00
31_V36_A1.7931.00
264_T468_G1.7901.00
47_D105_T1.7871.00
475_L508_A1.7861.00
169_W173_I1.7711.00
246_I250_I1.7571.00
469_K502_D1.7551.00
171_L334_L1.7471.00
249_A377_L1.7341.00
39_F136_V1.7331.00
154_P158_Q1.7301.00
220_T295_A1.7191.00
485_E489_Y1.7181.00
417_Q420_L1.7181.00
77_V102_L1.6981.00
417_Q427_S1.6941.00
536_D539_G1.6921.00
204_A208_L1.6911.00
80_P100_L1.6871.00
177_I332_Y1.6780.99
77_V104_V1.6680.99
499_A557_S1.6550.99
214_V341_M1.6520.99
420_L424_A1.6500.99
508_A520_L1.6400.99
35_Q38_A1.6300.99
361_V365_F1.6270.99
456_V460_N1.6190.99
286_S289_G1.6170.99
229_A322_M1.6100.99
450_F505_L1.6050.99
85_H97_R1.5980.99
164_P168_L1.5910.99
229_A232_G1.5600.99
258_S263_F1.5510.99
526_V531_T1.5470.99
494_P498_K1.5430.99
49_N103_P1.5340.99
485_E550_F1.5310.99
31_V55_K1.5280.99
266_Q272_Q1.5210.99
389_L400_W1.5080.99
87_D90_Y1.5060.99
120_Q129_Y1.4890.99
470_P502_D1.4860.99
170_A312_I1.4780.99
207_L211_F1.4680.99
18_F21_L1.4630.99
424_A427_S1.4630.99
269_S273_T1.4630.99
253_T370_L1.4570.99
510_V517_D1.4430.98
59_Y97_R1.4410.98
122_C128_C1.4380.98
212_I216_G1.4260.98
253_T373_P1.4200.98
44_N47_D1.4170.98
270_S273_T1.4130.98
396_A418_I1.4060.98
19_A23_D1.3900.98
474_D507_Q1.3880.98
551_M555_T1.3860.98
231_A234_Q1.3790.98
486_F551_M1.3730.98
387_L391_S1.3670.98
69_P72_A1.3670.98
547_V551_M1.3660.98
539_G542_H1.3660.98
208_L287_P1.3620.98
267_L271_L1.3610.98
88_E91_G1.3580.98
229_A326_G1.3550.98
471_V504_V1.3540.98
65_I100_L1.3520.98
229_A325_G1.3450.98
15_T20_G1.3410.97
456_V523_H1.3380.97
428_V432_Q1.3320.97
478_D484_K1.3290.97
295_A299_L1.3270.97
359_E362_K1.3180.97
405_S417_Q1.3130.97
429_R432_Q1.3120.97
243_Y247_G1.3110.97
306_T347_G1.3100.97
49_N101_T1.3090.97
429_R434_W1.3040.97
67_I104_V1.3040.97
470_P537_G1.3030.97
556_F559_H1.3020.97
475_L520_L1.2970.97
112_G137_P1.2910.97
17_V20_G1.2870.97
374_V389_L1.2850.97
458_E461_Q1.2820.97
366_G370_L1.2770.97
241_H246_I1.2730.97
423_A427_S1.2700.97
235_F238_A1.2680.96
216_G234_Q1.2610.96
498_K501_A1.2610.96
497_Q501_A1.2590.96
455_T458_E1.2570.96
169_W176_G1.2550.96
244_V248_L1.2520.96
236_Q379_R1.2480.96
30_F33_A1.2450.96
455_T506_L1.2430.96
428_V433_D1.2430.96
400_W403_I1.2430.96
72_A75_A1.2410.96
380_V384_V1.2380.96
181_P184_L1.2340.96
551_M559_H1.2340.96
228_V302_S1.2320.96
123_A129_Y1.2230.96
166_S328_T1.2200.96
398_F402_F1.2140.95
120_Q130_P1.2060.95
298_G302_S1.2060.95
52_W60_L1.2050.95
34_D119_Y1.1960.95
31_V35_Q1.1840.95
209_L290_V1.1840.95
20_G23_D1.1830.95
121_G129_Y1.1790.95
211_F215_Q1.1760.95
396_A400_W1.1750.95
69_P74_I1.1730.95
546_R549_G1.1690.94
56_D98_D1.1690.94
22_F25_P1.1640.94
482_A485_E1.1530.94
437_G440_H1.1530.94
239_L244_V1.1500.94
453_I456_V1.1460.94
515_A519_A1.1420.94
33_A36_A1.1420.94
100_L103_P1.1390.94
333_A348_N1.1380.94
264_T362_K1.1320.93
173_I176_G1.1160.93
184_L333_A1.1120.93
47_D103_P1.1120.93
239_L302_S1.1110.93
306_T317_A1.1100.93
452_Q456_V1.1040.93
155_Q159_P1.1040.93
428_V434_W1.1030.93
403_I417_Q1.1030.93
270_S274_R1.0970.92
255_L263_F1.0970.92
112_G139_S1.0950.92
51_T99_R1.0950.92
309_L325_G1.0950.92
487_E507_Q1.0940.92
552_D556_F1.0900.92
521_L526_V1.0870.92
397_F400_W1.0860.92
191_S343_I1.0770.92
371_A390_W1.0760.92
499_A503_T1.0740.92
30_F37_F1.0730.91
520_L524_L1.0670.91
19_A22_F1.0660.91
346_F350_L1.0630.91
374_V393_L1.0590.91
327_G331_L1.0570.91
548_T551_M1.0520.91
548_T555_T1.0450.90
30_F35_Q1.0440.90
462_A506_L1.0350.90
402_F417_Q1.0340.90
219_L291_F1.0300.90
16_S19_A1.0240.89
508_A517_D1.0200.89
489_Y553_A1.0130.89
32_P37_F1.0120.89
534_F559_H1.0090.89
403_I406_L1.0070.89
516_Q519_A1.0050.89
120_Q131_P1.0030.88
30_F123_A1.0000.88
274_R278_M1.0000.88
429_R439_T1.0000.88
14_S19_A0.9990.88
432_Q436_F0.9960.88
537_G540_Q0.9890.88
354_S358_M0.9870.88
255_L490_T0.9860.88
436_F440_H0.9860.88
298_G336_M0.9850.88
85_H95_I0.9850.88
474_D505_L0.9830.87
92_K120_Q0.9830.87
187_Y224_L0.9800.87
221_Y298_G0.9800.87
251_V254_L0.9760.87
301_C305_T0.9740.87
503_T534_F0.9740.87
50_L136_V0.9720.87
16_S23_D0.9700.87
493_D496_V0.9690.87
25_P28_S0.9660.87
305_T527_L0.9640.86
305_T310_S0.9630.86
370_L393_L0.9630.86
305_T529_L0.9580.86
555_T558_A0.9560.86
467_K470_P0.9550.86
252_F369_I0.9530.86
30_F36_A0.9470.85
188_P192_G0.9460.85
284_G289_G0.9420.85
79_L82_G0.9410.85
225_G325_G0.9350.85
457_D460_N0.9310.84
191_S194_V0.9310.84
302_S305_T0.9240.84
68_T72_A0.9220.84
171_L207_L0.9150.83
15_T18_F0.9130.83
292_V295_A0.9100.83
453_I506_L0.9090.83
227_V230_A0.9080.83
234_Q306_T0.9040.83
31_V129_Y0.9030.83
240_Q479_W0.9010.82
218_A330_Y0.9010.82
214_V334_L0.8990.82
225_G232_G0.8980.82
495_Q557_S0.8980.82
50_L117_V0.8970.82
311_A317_A0.8970.82
96_Y117_V0.8960.82
116_T133_T0.8930.82
476_Y507_Q0.8860.81
253_T257_M0.8840.81
58_Y82_G0.8830.81
377_L380_V0.8820.81
33_A37_F0.8810.81
235_F298_G0.8800.81
184_L195_L0.8780.81
13_C21_L0.8740.80
460_N463_L0.8730.80
455_T459_L0.8730.80
263_F275_L0.8710.80
32_P39_F0.8710.80
491_F556_F0.8700.80
75_A78_Q0.8660.80
395_V424_A0.8660.80
165_F169_W0.8640.80
20_G24_A0.8640.80
402_F405_S0.8620.80
322_M326_G0.8610.79
252_F302_S0.8600.79
264_T359_E0.8600.79
198_K201_L0.8580.79
59_Y65_I0.8570.79
415_I423_A0.8560.79
192_G195_L0.8530.79
79_L96_Y0.8520.79
218_A326_G0.8520.79
492_S557_S0.8510.79
381_I384_V0.8500.79
119_Y132_E0.8490.79
251_V324_L0.8460.78
115_L135_T0.8450.78
52_W102_L0.8440.78
20_G27_R0.8430.78
453_I473_L0.8410.78
260_F309_L0.8400.78
115_L136_V0.8380.78
443_Q515_A0.8370.78
275_L292_V0.8340.77
490_T496_V0.8340.77
237_A241_H0.8320.77
182_C304_C0.8300.77
345_V348_N0.8290.77
341_M345_V0.8280.77
500_L503_T0.8260.77
31_V58_Y0.8250.76
117_V140_E0.8250.76
542_H545_A0.8200.76
216_G379_R0.8170.76
38_A53_Q0.8170.76
453_I458_E0.8170.76
75_A107_N0.8150.76
203_T349_R0.8140.76
343_I481_V0.8110.75
21_L25_P0.8110.75
175_I254_L0.8090.75
363_T367_F0.8090.75
18_F24_A0.8090.75
541_E546_R0.8080.75
302_S332_Y0.8080.75
17_V21_L0.8040.75
170_A326_G0.8040.75
205_R208_L0.8040.75
432_Q435_A0.8030.75
68_T137_P0.8020.74
48_L115_L0.7980.74
232_G325_G0.7970.74
78_Q105_T0.7960.74
57_G123_A0.7960.74
307_A311_A0.7950.74
400_W405_S0.7900.73
60_L117_V0.7890.73
239_L325_G0.7860.73
489_Y492_S0.7860.73
448_L505_L0.7860.73
461_Q467_K0.7800.72
45_Q107_N0.7780.72
77_V105_T0.7770.72
547_V552_D0.7770.72
399_G403_I0.7760.72
17_V24_A0.7760.72
212_I290_V0.7740.72
374_V386_G0.7720.72
505_L520_L0.7700.71
320_G324_L0.7660.71
417_Q421_L0.7650.71
59_Y121_G0.7650.71
276_T279_S0.7650.71
506_L517_D0.7650.71
459_L463_L0.7650.71
456_V524_L0.7640.71
456_V462_A0.7630.71
435_A440_H0.7600.70
222_T326_G0.7590.70
306_T528_G0.7580.70
18_F22_F0.7560.70
58_Y307_A0.7550.70
369_I372_L0.7550.70
15_T23_D0.7540.70
249_A373_P0.7500.69
275_L278_M0.7500.69
266_Q302_S0.7490.69
431_L440_H0.7490.69
266_Q269_S0.7480.69
217_M336_M0.7470.69
399_G404_T0.7460.69
367_F400_W0.7460.69
517_D521_L0.7440.69
288_G292_V0.7430.69
171_L175_I0.7430.69
547_V557_S0.7430.69
85_H90_Y0.7420.69
411_G414_R0.7410.68
213_Y290_V0.7400.68
470_P503_T0.7390.68
31_V121_G0.7390.68
234_Q379_R0.7390.68
394_G427_S0.7370.68
235_F301_C0.7360.68
310_S529_L0.7320.68
65_I79_L0.7310.67
301_C529_L0.7310.67
23_D26_G0.7310.67
189_L297_A0.7310.67
59_Y67_I0.7300.67
300_I305_T0.7290.67
298_G305_T0.7280.67
440_H445_Q0.7270.67
444_T447_H0.7250.67
31_V38_A0.7240.67
242_P250_I0.7240.67
190_I210_T0.7230.67
87_D93_S0.7230.67
308_P329_L0.7230.67
476_Y482_A0.7210.66
217_M245_L0.7180.66
305_T309_L0.7160.66
163_L327_G0.7140.66
165_F168_L0.7120.65
386_G389_L0.7120.65
547_V550_F0.7120.65
493_D553_A0.7120.65
407_Q411_G0.7090.65
65_I120_Q0.7090.65
60_L65_I0.7090.65
176_G361_V0.7080.65
188_P370_L0.7080.65
298_G312_I0.7070.65
154_P160_T0.7070.65
187_Y475_L0.7070.65
177_I312_I0.7060.65
165_F172_L0.7050.65
17_V25_P0.7040.65
513_N517_D0.7030.64
82_G89_F0.7000.64
170_A297_A0.6990.64
279_S343_I0.6980.64
414_R417_Q0.6980.64
27_R30_F0.6960.64
412_W416_V0.6940.63
532_I547_V0.6940.63
67_I102_L0.6940.63
285_G290_V0.6930.63
190_I354_S0.6920.63
231_A317_A0.6910.63
14_S20_G0.6880.63
396_A417_Q0.6850.62
30_F55_K0.6850.62
430_P433_D0.6840.62
193_I293_M0.6830.62
231_A391_S0.6820.62
48_L138_L0.6810.62
13_C16_S0.6800.62
440_H443_Q0.6800.62
59_Y89_F0.6800.62
496_V499_A0.6800.62
367_F402_F0.6790.62
496_V500_L0.6780.62
85_H124_D0.6780.62
123_A127_F0.6780.62
39_F42_Q0.6770.61
410_R414_R0.6740.61
211_F345_V0.6730.61
309_L478_D0.6720.61
55_K58_Y0.6710.61
434_W437_G0.6690.61
88_E92_K0.6690.61
171_L343_I0.6690.61
218_A222_T0.6680.60
485_E490_T0.6680.60
359_E363_T0.6660.60
216_G295_A0.6650.60
162_Q292_V0.6640.60
32_P38_A0.6640.60
536_D542_H0.6630.60
58_Y62_R0.6630.60
470_P534_F0.6610.60
50_L115_L0.6600.60
50_L104_V0.6590.59
298_G310_S0.6580.59
252_F255_L0.6580.59
337_G347_G0.6570.59
224_L314_L0.6560.59
354_S372_L0.6550.59
169_W289_G0.6540.59
225_G229_A0.6530.59
113_A140_E0.6530.59
181_P215_Q0.6520.59
294_G335_G0.6500.58
482_A486_F0.6500.58
194_V344_T0.6500.58
43_Q138_L0.6500.58
344_T348_N0.6490.58
178_A369_I0.6480.58
245_L375_F0.6460.58
390_W393_L0.6450.58
234_Q291_F0.6450.58
209_L213_Y0.6450.58
230_A322_M0.6440.58
239_L300_I0.6440.58
490_T552_D0.6430.58
435_A439_T0.6430.58
399_G417_Q0.6410.57
235_F531_T0.6410.57
490_T553_A0.6400.57
467_K504_V0.6400.57
479_W509_N0.6400.57
168_L171_L0.6400.57
172_L338_L0.6390.57
452_Q457_D0.6380.57
16_S22_F0.6380.57
14_S18_F0.6350.57
356_P359_E0.6350.57
37_F129_Y0.6340.56
499_A502_D0.6340.56
465_E533_L0.6330.56
250_I514_D0.6330.56
41_F138_L0.6330.56
60_L95_I0.6320.56
52_W117_V0.6320.56
360_Q363_T0.6310.56
446_T467_K0.6300.56
189_L330_Y0.6300.56
431_L434_W0.6290.56
504_V536_D0.6270.56
428_V431_L0.6270.56
314_L317_A0.6270.56
36_A39_F0.6270.56
472_M505_L0.6260.56
58_Y129_Y0.6260.56
15_T19_A0.6230.55
295_A332_Y0.6230.55
325_G340_L0.6210.55
235_F310_S0.6210.55
418_I427_S0.6210.55
46_H106_I0.6200.55
246_I377_L0.6190.55
233_L298_G0.6190.55
436_F439_T0.6180.55
251_V545_A0.6180.55
54_I98_D0.6180.55
170_A190_I0.6170.54
202_S205_R0.6170.54
460_N519_A0.6160.54
433_D437_G0.6130.54
358_M374_V0.6130.54
216_G236_Q0.6120.54
121_G131_P0.6120.54
390_W394_G0.6120.54
203_T207_L0.6120.54
238_A486_F0.6100.54
85_H120_Q0.6080.53
416_V427_S0.6060.53
244_V255_L0.6050.53
300_I490_T0.6030.53
283_Q419_I0.6030.53
33_A38_A0.6030.53
259_M362_K0.6030.53
220_T378_E0.6020.53
473_L535_F0.6020.53
302_S306_T0.6010.53
77_V381_I0.6010.53
465_E468_G0.6010.53
220_T298_G0.6000.52
236_Q291_F0.6000.52
173_I318_Q0.5990.52
45_Q105_T0.5990.52
173_I312_I0.5990.52
534_F560_L0.5990.52
15_T22_F0.5970.52
59_Y87_D0.5970.52
60_L120_Q0.5970.52
305_T528_G0.5960.52
195_L344_T0.5950.52
279_S283_Q0.5950.52
83_V98_D0.5940.52
154_P157_E0.5940.52
169_W225_G0.5930.52
57_G74_I0.5910.51
327_G498_K0.5910.51
557_S560_L0.5900.51
536_D541_E0.5890.51
330_Y334_L0.5890.51
306_T375_F0.5880.51
258_S262_L0.5870.51
248_L301_C0.5860.51
37_F121_G0.5860.51
400_W404_T0.5850.51
300_I363_T0.5840.51
65_I94_E0.5830.50
184_L400_W0.5810.50
506_L520_L0.5800.50
293_M366_G0.5800.50
477_A509_N0.5800.50
30_F38_A0.5780.50
486_F508_A0.5780.50
478_D507_Q0.5780.50
225_G314_L0.5760.50
306_T550_F0.5750.49
407_Q410_R0.5750.49
60_L119_Y0.5730.49
371_A405_S0.5720.49
225_G330_Y0.5720.49
472_M532_I0.5700.49
243_Y248_L0.5700.49
210_T532_I0.5680.49
303_P310_S0.5680.49
82_G129_Y0.5670.48
274_R277_L0.5670.48
133_T136_V0.5660.48
513_N518_V0.5650.48
226_L326_G0.5650.48
457_D461_Q0.5640.48
76_D105_T0.5640.48
443_Q446_T0.5640.48
312_I328_T0.5630.48
205_R209_L0.5630.48
225_G244_V0.5630.48
468_G504_V0.5630.48
30_F58_Y0.5620.48
272_Q302_S0.5610.48
405_S414_R0.5610.48
381_I403_I0.5600.48
236_Q239_L0.5590.48
507_Q532_I0.5590.48
235_F312_I0.5590.48
190_I194_V0.5590.48
236_Q314_L0.5580.47
417_Q424_A0.5580.47
36_A129_Y0.5570.47
259_M524_L0.5570.47
263_F429_R0.5570.47
420_L427_S0.5570.47
178_A335_G0.5560.47
394_G423_A0.5550.47
439_T442_A0.5550.47
208_L211_F0.5540.47
86_E89_F0.5530.47
519_A522_K0.5530.47
482_A487_E0.5530.47
123_A130_P0.5530.47
32_P36_A0.5530.47
17_V23_D0.5530.47
402_F406_L0.5520.47
422_A498_K0.5520.47
206_A345_V0.5500.46
277_L353_K0.5500.46
302_S376_L0.5490.46
54_I97_R0.5480.46
252_F340_L0.5470.46
373_P377_L0.5470.46
219_L333_A0.5460.46
177_I335_G0.5450.46
379_R386_G0.5450.46
520_L533_L0.5440.46
205_R401_A0.5440.46
183_V305_T0.5440.46
329_L529_L0.5440.46
225_G251_V0.5440.46
88_E97_R0.5430.46
211_F341_M0.5430.46
17_V22_F0.5430.46
233_L521_L0.5430.46
64_Q82_G0.5420.45
442_A445_Q0.5420.45
356_P417_Q0.5420.45
275_L279_S0.5410.45
180_T306_T0.5400.45
54_I60_L0.5380.45
59_Y553_A0.5380.45
471_V474_D0.5370.45
481_V510_V0.5360.45
162_Q515_A0.5360.45
65_I119_Y0.5360.45
173_I231_A0.5350.45
213_Y300_I0.5350.45
531_T549_G0.5340.45
210_T214_V0.5340.45
210_T340_L0.5340.45
60_L121_G0.5340.45
220_T236_Q0.5340.45
371_A374_V0.5330.44
110_S139_S0.5330.44
235_F305_T0.5320.44
61_Y87_D0.5320.44
234_Q305_T0.5320.44
450_F507_Q0.5320.44
450_F456_V0.5300.44
341_M344_T0.5300.44
486_F517_D0.5300.44
508_A524_L0.5280.44
99_R103_P0.5280.44
389_L396_A0.5270.44
371_A393_L0.5260.44
238_A317_A0.5260.44
310_S347_G0.5250.43
39_F52_W0.5240.43
52_W100_L0.5230.43
526_V548_T0.5230.43
218_A336_M0.5230.43
401_A431_L0.5220.43
239_L380_V0.5220.43
62_R65_I0.5210.43
41_F137_P0.5210.43
290_V333_A0.5210.43
486_F490_T0.5200.43
481_V485_E0.5200.43
179_F492_S0.5200.43
48_L136_V0.5200.43
106_I407_Q0.5200.43
303_P479_W0.5190.43
179_F361_V0.5190.43
213_Y367_F0.5180.43
295_A401_A0.5180.43
216_G302_S0.5180.43
291_F333_A0.5170.43
419_I558_A0.5160.42
475_L505_L0.5160.42
258_S261_G0.5160.42
70_E74_I0.5150.42
121_G549_G0.5150.42
290_V472_M0.5150.42
315_Y320_G0.5150.42
272_Q275_L0.5140.42
392_A425_L0.5140.42
213_Y431_L0.5140.42
495_Q553_A0.5130.42
163_L324_L0.5130.42
56_D76_D0.5120.42
231_A238_A0.5110.42
80_P120_Q0.5110.42
52_W119_Y0.5110.42
41_F374_V0.5100.42
173_I235_F0.5090.42
430_P439_T0.5090.42
177_I190_I0.5090.42
195_L298_G0.5090.42
315_Y319_S0.5060.41
412_W415_I0.5060.41
358_M361_V0.5060.41
136_V508_A0.5050.41
63_K82_G0.5050.41
184_L307_A0.5050.41
138_L287_P0.5040.41
178_A490_T0.5040.41
80_P138_L0.5040.41
186_M190_I0.5040.41
241_H344_T0.5040.41
166_S336_M0.5040.41
191_S300_I0.5040.41
377_L385_W0.5030.41
237_A245_L0.5030.41
303_P477_A0.5030.41
478_D487_E0.5020.41
324_L328_T0.5020.41
144_N501_A0.5010.41
422_A515_A0.5010.41
476_Y509_N0.5010.41
550_F555_T0.5010.41
473_L534_F0.5010.41
363_T400_W0.5000.41
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2k0rA 1 0.2212 100 0.832 Contact Map
1l6pA 1 0.2142 100 0.832 Contact Map
3pfuA 1 0.2106 100 0.833 Contact Map
1jpeA 1 0.2053 100 0.835 Contact Map
2ec4A 1 0.2496 99.9 0.87 Contact Map
4nv5A 1 0.4407 99.8 0.882 Contact Map
2fwhA 1 0.2071 99.8 0.882 Contact Map
2dlxA 1 0.2336 99.8 0.884 Contact Map
3iraA 1 0.2336 99.7 0.894 Contact Map
2av4A 3 0.1982 99.6 0.899 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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