CUEO - ECOLI - GREMLIN Contacts

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CUEO - Blue copper oxidase CueO

UniProt:	P36649	Sequences: MQRRDFLKYSVALGVASALPLWSRAVFAAERPTLPIPDLLTTDARNRIQLTIGAGQSTFGGKTATTWGYNGNLLGPAVKLQRGKAVTVDIYNQLTEETTLHWHGLEVPGEVDGGPQGIIPPGGKRSVTLNVDQPAATCWFHPHQHGKTGRQVAMGLAGLVVIEDDEILKLMLPKQWGIDDVPVIVQDKKFSADGQIDYQLDVMTAAVGWFGDTLLTNGAIYPQHAAPRGWLRLRLLNGCNARSLNFATSDNRPLYVIASDGGLLPEPVKVSELPVLMGERFEVLVEVNDNKPFDLVTLPVSQMGMAIAPFDKPHPVMRIQPIAISASGALPDTLSSLPALPSLEGLTVRKLQLSMDPMLDMMGMQMLMEKYGDQAMAGMDHSQMMGHMGHGNMNHMNHGGKFDFHHANKINGQAFDMNKPMFAAAKGQYERWVISGVGDMMLHPFHIHGTQFRILSENGKPPAAHRAGWKDTVKVEGNVSEVLVKFNHDAPKEHAYMAHCHLLEHEDTGMMLGFTV	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG12318
Length:	516 (442)
Sequences:	5794 (4290)
Seq/√Len:	204.1

ECOLI - CUEO FTSP
BACSU - COTA
HALSA - Q9HQF4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
79_K	163_E	5.432	1.00
87_T	128_T	4.932	1.00
85_A	128_T	4.383	1.00
51_T	93_Q	4.146	1.00
49_Q	89_D	4.025	1.00
89_D	126_S	3.853	1.00
49_Q	91_Y	3.747	1.00
279_E	470_K	3.742	1.00
230_W	284_L	3.595	1.00
77_A	159_L	3.544	1.00
55_G	68_G	3.493	1.00
235_L	283_V	3.315	1.00
473_V	482_V	3.264	1.00
90_I	119_I	3.124	1.00
91_Y	124_K	3.073	1.00
57_S	66_T	3.016	1.00
47_R	87_T	2.988	1.00
258_A	282_E	2.885	1.00
254_L	283_V	2.744	1.00
235_L	246_F	2.717	1.00
434_I	445_F	2.664	1.00
275_V	281_F	2.620	1.00
253_P	269_K	2.576	1.00
159_L	236_L	2.570	1.00
230_W	286_E	2.551	1.00
56_Q	63_T	2.539	1.00
433_V	483_L	2.423	1.00
47_R	89_D	2.384	1.00
425_A	428_Q	2.300	1.00
233_L	283_V	2.253	1.00
184_I	238_G	2.247	1.00
56_Q	65_T	2.245	1.00
111_V	125_R	2.240	1.00
248_T	285_V	2.227	1.00
82_R	164_D	2.202	1.00
253_P	271_S	2.187	1.00
140_F	158_G	2.154	1.00
51_T	91_Y	2.115	1.00
120_P	123_G	2.105	1.00
54_A	65_T	2.081	1.00
179_D	229_G	2.067	1.00
68_G	73_L	2.033	1.00
228_R	287_V	2.030	1.00
226_A	287_V	2.027	1.00
53_G	93_Q	2.022	1.00
433_V	481_E	2.004	1.00
81_Q	163_E	1.992	1.00
85_A	130_N	1.992	1.00
262_G	451_Q	1.981	1.00
434_I	484_V	1.958	1.00
97_E	120_P	1.955	1.00
431_R	485_K	1.951	1.00
476_E	480_S	1.942	1.00
159_L	184_I	1.929	1.00
232_R	282_E	1.855	1.00
452_F	484_V	1.841	1.00
243_S	474_K	1.817	1.00
431_R	455_L	1.810	1.00
259_S	281_F	1.797	1.00
343_L	346_L	1.762	1.00
432_W	484_V	1.754	1.00
235_L	273_L	1.737	1.00
345_G	348_V	1.699	1.00
89_D	124_K	1.687	1.00
255_Y	269_K	1.678	1.00
280_R	471_D	1.676	1.00
239_C	244_L	1.673	1.00
273_L	281_F	1.666	1.00
191_S	195_Q	1.661	1.00
331_P	334_L	1.661	1.00
52_I	98_T	1.651	1.00
80_L	86_V	1.649	1.00
337_L	340_L	1.649	1.00
232_R	257_I	1.645	1.00
497_M	511_M	1.640	1.00
46_N	84_K	1.617	1.00
54_A	95_T	1.616	1.00
157_A	186_Q	1.616	1.00
456_S	483_L	1.605	1.00
345_G	349_R	1.601	1.00
296_V	317_M	1.596	1.00
77_A	182_P	1.578	1.00
52_I	90_I	1.571	1.00
138_C	261_G	1.561	1.00
346_L	349_R	1.556	1.00
434_I	498_A	1.555	1.00
276_L	474_K	1.555	1.00
142_P	151_Q	1.513	1.00
183_V	235_L	1.506	1.00
495_A	513_G	1.489	1.00
69_Y	140_F	1.484	1.00
82_R	165_D	1.456	1.00
447_I	486_F	1.453	1.00
349_R	352_Q	1.450	1.00
159_L	182_P	1.437	1.00
205_A	208_G	1.430	1.00
225_A	320_Q	1.427	1.00
429_Y	487_N	1.426	1.00
60_G	190_F	1.419	1.00
424_A	430_E	1.418	1.00
356_D	359_L	1.415	1.00
352_Q	355_M	1.392	1.00
343_L	347_T	1.390	1.00
334_L	337_L	1.377	1.00
256_V	281_F	1.373	1.00
80_L	131_V	1.368	1.00
246_F	273_L	1.363	1.00
346_L	350_K	1.355	1.00
66_T	188_K	1.354	1.00
87_T	126_S	1.344	1.00
453_R	469_W	1.329	1.00
405_H	408_N	1.323	1.00
209_W	212_D	1.315	1.00
273_L	283_V	1.312	1.00
223_Q	318_R	1.308	1.00
391_G	394_N	1.308	1.00
58_T	63_T	1.302	1.00
375_A	379_M	1.300	1.00
454_I	473_V	1.298	1.00
347_T	351_L	1.282	1.00
98_T	151_Q	1.281	1.00
332_D	335_S	1.260	1.00
342_S	346_L	1.256	1.00
456_S	481_E	1.247	1.00
250_D	297_T	1.246	1.00
501_H	505_H	1.240	1.00
447_I	498_A	1.238	1.00
153_A	240_N	1.237	1.00
315_P	319_I	1.233	1.00
216_T	315_P	1.233	1.00
506_E	511_M	1.233	1.00
381_H	384_M	1.231	1.00
246_F	296_V	1.230	1.00
86_V	160_V	1.230	1.00
254_L	285_V	1.229	1.00
330_L	333_T	1.229	1.00
317_M	321_P	1.228	1.00
67_W	156_L	1.223	1.00
82_R	133_Q	1.220	1.00
358_M	361_M	1.218	1.00
430_E	486_F	1.216	1.00
390_H	393_M	1.213	1.00
442_L	474_K	1.207	1.00
449_G	496_Y	1.201	1.00
503_L	506_E	1.201	1.00
256_V	270_V	1.200	1.00
364_M	367_L	1.199	1.00
316_V	319_I	1.198	1.00
376_M	379_M	1.195	1.00
248_T	254_L	1.193	1.00
348_V	351_L	1.191	1.00
266_E	466_R	1.181	1.00
52_I	69_Y	1.177	1.00
186_Q	215_L	1.168	1.00
163_E	180_D	1.163	1.00
500_C	505_H	1.162	1.00
48_I	80_L	1.156	1.00
226_A	231_L	1.155	1.00
294_D	298_L	1.151	1.00
408_N	411_N	1.142	1.00
245_N	272_E	1.136	1.00
245_N	274_P	1.134	1.00
76_P	140_F	1.128	1.00
369_E	372_G	1.114	1.00
143_H	500_C	1.111	1.00
152_V	503_L	1.108	1.00
412_G	415_F	1.107	1.00
109_G	113_G	1.107	1.00
53_G	68_G	1.104	1.00
342_S	345_G	1.100	1.00
137_T	234_R	1.094	1.00
119_I	125_R	1.085	1.00
325_S	331_P	1.084	1.00
349_R	353_L	1.083	1.00
370_K	373_D	1.081	1.00
431_R	483_L	1.080	1.00
99_T	115_P	1.061	1.00
50_L	78_V	1.056	1.00
157_A	238_G	1.056	1.00
57_S	68_G	1.053	1.00
309_P	312_K	1.053	1.00
409_K	416_D	1.052	1.00
405_H	409_K	1.052	1.00
259_S	470_K	1.051	1.00
345_G	352_Q	1.050	1.00
221_Y	224_H	1.050	1.00
69_Y	156_L	1.047	1.00
67_W	154_M	1.046	1.00
349_R	355_M	1.037	1.00
346_L	352_Q	1.029	1.00
251_N	289_D	1.027	1.00
351_L	355_M	1.026	1.00
219_A	222_P	1.020	1.00
367_L	370_K	1.018	1.00
387_H	390_H	1.017	1.00
294_D	300_V	1.007	1.00
353_L	356_D	1.005	1.00
226_A	317_M	1.002	1.00
154_M	193_D	1.002	1.00
330_L	335_S	0.999	1.00
457_E	480_S	0.998	1.00
90_I	98_T	0.995	1.00
443_H	501_H	0.995	1.00
81_Q	84_K	0.991	1.00
345_G	351_L	0.990	1.00
341_P	344_E	0.990	1.00
192_A	195_Q	0.982	1.00
315_P	321_P	0.980	1.00
297_T	300_V	0.979	1.00
348_V	353_L	0.979	1.00
234_R	282_E	0.979	1.00
115_P	144_Q	0.977	1.00
445_F	510_M	0.973	1.00
116_Q	125_R	0.969	1.00
345_G	354_S	0.969	1.00
293_F	297_T	0.969	1.00
214_L	244_L	0.968	1.00
81_Q	165_D	0.967	1.00
90_I	100_L	0.966	1.00
143_H	501_H	0.965	1.00
312_K	316_V	0.962	0.99
350_K	353_L	0.962	0.99
76_P	158_G	0.961	0.99
222_P	226_A	0.959	0.99
314_H	317_M	0.957	0.99
137_T	236_L	0.957	0.99
185_V	246_F	0.955	0.99
408_N	412_G	0.952	0.99
243_S	276_L	0.951	0.99
355_M	359_L	0.950	0.99
316_V	321_P	0.948	0.99
350_K	355_M	0.946	0.99
235_L	275_V	0.945	0.99
372_G	375_A	0.944	0.99
443_H	500_C	0.941	0.99
355_M	361_M	0.940	0.99
353_L	359_L	0.937	0.99
253_P	288_N	0.937	0.99
371_Y	374_Q	0.933	0.99
75_G	218_G	0.931	0.99
67_W	94_L	0.930	0.99
184_I	236_L	0.930	0.99
342_S	349_R	0.930	0.99
344_E	348_V	0.925	0.99
355_M	358_M	0.923	0.99
189_K	196_I	0.920	0.99
180_D	234_R	0.916	0.99
347_T	354_S	0.913	0.99
327_S	332_D	0.912	0.99
379_M	382_S	0.910	0.99
452_F	473_V	0.909	0.99
357_P	361_M	0.908	0.99
80_L	160_V	0.908	0.99
252_R	319_I	0.906	0.99
45_R	87_T	0.896	0.99
226_A	285_V	0.896	0.99
214_L	313_P	0.894	0.99
248_T	296_V	0.892	0.99
374_Q	378_G	0.892	0.99
231_L	287_V	0.890	0.99
379_M	384_M	0.889	0.99
324_I	327_S	0.886	0.99
341_P	345_G	0.885	0.99
79_K	180_D	0.884	0.99
335_S	338_P	0.880	0.99
331_P	338_P	0.879	0.99
143_H	499_H	0.878	0.99
444_P	502_L	0.876	0.99
499_H	505_H	0.875	0.99
191_S	199_Q	0.873	0.99
329_A	332_D	0.872	0.99
407_A	410_I	0.872	0.99
345_G	350_K	0.872	0.99
455_L	485_K	0.872	0.99
257_I	284_L	0.870	0.99
164_D	167_I	0.869	0.99
347_T	359_L	0.867	0.99
424_A	488_H	0.865	0.99
141_H	500_C	0.865	0.99
73_L	157_A	0.863	0.99
182_P	236_L	0.863	0.99
329_A	333_T	0.862	0.99
368_M	372_G	0.861	0.99
355_M	360_D	0.860	0.99
344_E	349_R	0.858	0.99
411_N	414_A	0.858	0.99
443_H	446_H	0.857	0.99
330_L	334_L	0.857	0.99
213_T	220_I	0.857	0.99
141_H	501_H	0.855	0.99
427_G	488_H	0.853	0.99
313_P	316_V	0.851	0.99
318_R	323_A	0.851	0.99
454_I	482_V	0.851	0.99
362_M	366_M	0.850	0.99
96_E	151_Q	0.848	0.99
233_L	285_V	0.848	0.99
319_I	322_I	0.847	0.99
318_R	321_P	0.846	0.99
102_W	129_L	0.844	0.99
75_G	156_L	0.843	0.99
390_H	394_N	0.843	0.99
204_T	208_G	0.839	0.99
451_Q	469_W	0.838	0.99
71_G	74_L	0.838	0.99
314_H	319_I	0.836	0.99
105_L	160_V	0.830	0.98
181_V	233_L	0.829	0.98
349_R	356_D	0.829	0.98
463_A	466_R	0.827	0.98
185_V	244_L	0.826	0.98
339_A	343_L	0.825	0.98
106_E	451_Q	0.825	0.98
408_N	414_A	0.824	0.98
354_S	360_D	0.819	0.98
103_H	143_H	0.815	0.98
357_P	360_D	0.814	0.98
320_Q	323_A	0.807	0.98
294_D	301_S	0.805	0.98
256_V	273_L	0.802	0.98
80_L	162_I	0.801	0.98
372_G	376_M	0.800	0.98
297_T	302_Q	0.799	0.98
327_S	330_L	0.798	0.98
167_I	170_L	0.798	0.98
370_K	374_Q	0.797	0.98
333_T	337_L	0.797	0.98
343_L	349_R	0.797	0.98
82_R	134_P	0.797	0.98
387_H	391_G	0.795	0.98
497_M	506_E	0.795	0.98
342_S	347_T	0.795	0.98
339_A	342_S	0.795	0.98
294_D	297_T	0.794	0.98
346_L	353_L	0.793	0.98
258_A	263_L	0.793	0.98
110_E	113_G	0.793	0.98
204_T	207_V	0.793	0.98
354_S	357_P	0.792	0.98
387_H	392_N	0.791	0.98
313_P	317_M	0.790	0.98
308_A	311_D	0.789	0.98
335_S	339_A	0.788	0.98
432_W	514_F	0.786	0.98
45_R	85_A	0.785	0.98
350_K	356_D	0.784	0.98
406_H	411_N	0.783	0.98
247_A	271_S	0.783	0.98
356_D	360_D	0.782	0.98
69_Y	100_L	0.782	0.98
58_T	61_G	0.781	0.98
428_Q	488_H	0.779	0.98
352_Q	357_P	0.777	0.98
443_H	448_H	0.776	0.98
186_Q	238_G	0.773	0.98
106_E	489_D	0.772	0.98
259_S	264_L	0.771	0.98
317_M	320_Q	0.770	0.98
240_N	504_E	0.767	0.97
443_H	505_H	0.767	0.97
48_I	86_V	0.763	0.97
373_D	377_A	0.763	0.97
347_T	350_K	0.762	0.97
389_G	394_N	0.762	0.97
47_R	128_T	0.762	0.97
348_V	352_Q	0.758	0.97
380_D	384_M	0.757	0.97
344_E	347_T	0.757	0.97
366_M	369_E	0.756	0.97
52_I	156_L	0.754	0.97
447_I	484_V	0.754	0.97
343_L	348_V	0.753	0.97
351_L	356_D	0.751	0.97
348_V	355_M	0.749	0.97
141_H	443_H	0.747	0.97
378_G	381_H	0.747	0.97
106_E	490_A	0.746	0.97
103_H	141_H	0.743	0.97
297_T	301_S	0.742	0.97
368_M	371_Y	0.740	0.97
295_L	299_P	0.736	0.97
436_G	477_G	0.732	0.97
413_Q	416_D	0.732	0.97
90_I	102_W	0.732	0.97
376_M	381_H	0.728	0.97
315_P	318_R	0.728	0.97
105_L	162_I	0.726	0.96
103_H	501_H	0.725	0.96
353_L	361_M	0.724	0.96
344_E	353_L	0.724	0.96
343_L	352_Q	0.724	0.96
103_H	500_C	0.721	0.96
101_H	143_H	0.719	0.96
463_A	467_A	0.718	0.96
356_D	361_M	0.717	0.96
185_V	235_L	0.714	0.96
389_G	393_M	0.712	0.96
131_V	160_V	0.709	0.96
325_S	329_A	0.708	0.96
247_A	272_E	0.707	0.96
208_G	211_G	0.707	0.96
50_L	140_F	0.706	0.96
353_L	358_M	0.706	0.96
446_H	500_C	0.706	0.96
221_Y	226_A	0.704	0.96
99_T	144_Q	0.704	0.96
365_Q	368_M	0.702	0.96
93_Q	122_G	0.701	0.96
346_L	351_L	0.701	0.96
264_L	268_V	0.699	0.96
409_K	412_G	0.699	0.96
77_A	161_V	0.698	0.96
310_F	321_P	0.698	0.96
70_N	74_L	0.698	0.96
88_V	102_W	0.697	0.96
70_N	76_P	0.694	0.95
203_M	208_G	0.693	0.95
387_H	394_N	0.693	0.95
169_K	284_L	0.693	0.95
157_A	184_I	0.692	0.95
86_V	129_L	0.692	0.95
346_L	355_M	0.690	0.95
295_L	300_V	0.690	0.95
377_A	380_D	0.690	0.95
445_F	498_A	0.687	0.95
180_D	232_R	0.687	0.95
152_V	157_A	0.686	0.95
374_Q	377_A	0.686	0.95
342_S	351_L	0.682	0.95
300_V	303_M	0.682	0.95
352_Q	356_D	0.681	0.95
252_R	288_N	0.680	0.95
137_T	159_L	0.679	0.95
69_Y	75_G	0.677	0.95
138_C	162_I	0.675	0.95
203_M	207_V	0.675	0.95
343_L	350_K	0.675	0.95
411_N	415_F	0.675	0.95
75_G	140_F	0.672	0.95
324_I	328_G	0.671	0.95
333_T	338_P	0.671	0.95
498_A	512_L	0.670	0.95
332_D	337_L	0.669	0.94
342_S	348_V	0.669	0.94
443_H	499_H	0.668	0.94
103_H	443_H	0.668	0.94
181_V	231_L	0.667	0.94
447_I	452_F	0.665	0.94
166_E	170_L	0.662	0.94
296_V	300_V	0.662	0.94
203_M	206_A	0.660	0.94
329_A	334_L	0.660	0.94
354_S	359_L	0.660	0.94
333_T	336_S	0.659	0.94
310_F	319_I	0.658	0.94
60_G	64_A	0.658	0.94
53_G	71_G	0.656	0.94
169_K	263_L	0.655	0.94
143_H	505_H	0.655	0.94
375_A	378_G	0.654	0.94
416_D	419_K	0.653	0.94
164_D	263_L	0.650	0.94
208_G	441_M	0.650	0.94
410_I	416_D	0.649	0.94
77_A	80_L	0.649	0.94
294_D	299_P	0.648	0.94
344_E	352_Q	0.646	0.93
102_W	160_V	0.645	0.93
379_M	445_F	0.642	0.93
376_M	380_D	0.641	0.93
425_A	430_E	0.640	0.93
77_A	163_E	0.640	0.93
405_H	412_G	0.639	0.93
415_F	418_N	0.638	0.93
259_S	279_E	0.637	0.93
190_F	213_T	0.636	0.93
317_M	322_I	0.636	0.93
315_P	323_A	0.636	0.93
318_R	322_I	0.634	0.93
372_G	377_A	0.632	0.93
325_S	332_D	0.632	0.93
427_G	487_N	0.631	0.93
161_V	236_L	0.631	0.93
54_A	67_W	0.630	0.93
367_L	371_Y	0.630	0.93
383_Q	386_G	0.629	0.92
223_Q	320_Q	0.629	0.92
227_P	288_N	0.626	0.92
255_Y	286_E	0.626	0.92
367_L	372_G	0.625	0.92
350_K	354_S	0.624	0.92
252_R	294_D	0.623	0.92
62_K	190_F	0.623	0.92
422_F	512_L	0.622	0.92
361_M	364_M	0.621	0.92
256_V	268_V	0.620	0.92
388_M	392_N	0.620	0.92
77_A	140_F	0.620	0.92
350_K	357_P	0.619	0.92
314_H	321_P	0.618	0.92
435_S	481_E	0.617	0.92
239_C	277_M	0.615	0.92
376_M	382_S	0.614	0.92
446_H	501_H	0.614	0.92
386_G	391_G	0.613	0.92
94_L	121_P	0.612	0.91
319_I	323_A	0.611	0.91
222_P	225_A	0.609	0.91
331_P	336_S	0.609	0.91
342_S	354_S	0.606	0.91
259_S	468_G	0.606	0.91
346_L	356_D	0.606	0.91
371_Y	375_A	0.604	0.91
384_M	387_H	0.602	0.91
256_V	283_V	0.600	0.91
409_K	413_Q	0.600	0.91
133_Q	162_I	0.598	0.91
178_I	231_L	0.598	0.91
426_K	491_P	0.598	0.91
243_S	274_P	0.597	0.90
309_P	313_P	0.596	0.90
309_P	314_H	0.594	0.90
412_G	416_D	0.592	0.90
352_Q	358_M	0.592	0.90
328_G	332_D	0.590	0.90
42_T	45_R	0.590	0.90
325_S	328_G	0.588	0.90
407_A	414_A	0.587	0.90
410_I	413_Q	0.586	0.90
369_E	374_Q	0.586	0.90
475_V	482_V	0.585	0.90
447_I	450_T	0.584	0.89
351_L	357_P	0.583	0.89
327_S	331_P	0.583	0.89
143_H	448_H	0.580	0.89
101_H	448_H	0.580	0.89
54_A	94_L	0.579	0.89
295_L	298_L	0.578	0.89
276_L	279_E	0.574	0.89
313_P	319_I	0.574	0.89
299_P	302_Q	0.573	0.89
106_E	132_D	0.572	0.88
389_G	392_N	0.572	0.88
433_V	484_V	0.571	0.88
335_S	340_L	0.571	0.88
190_F	212_D	0.570	0.88
350_K	359_L	0.569	0.88
369_E	375_A	0.569	0.88
177_G	180_D	0.569	0.88
67_W	95_T	0.568	0.88
360_D	364_M	0.567	0.88
327_S	333_T	0.567	0.88
170_L	263_L	0.566	0.88
139_W	143_H	0.566	0.88
345_G	356_D	0.565	0.88
410_I	414_A	0.565	0.88
49_Q	72_N	0.565	0.88
312_K	319_I	0.564	0.88
375_A	380_D	0.563	0.88
103_H	448_H	0.562	0.88
71_G	75_G	0.562	0.88
227_P	287_V	0.562	0.88
59_F	190_F	0.561	0.88
111_V	129_L	0.561	0.88
458_N	481_E	0.561	0.88
80_L	105_L	0.561	0.88
364_M	369_E	0.560	0.87
348_V	360_D	0.560	0.87
101_H	104_G	0.559	0.87
345_G	353_L	0.558	0.87
254_L	270_V	0.556	0.87
380_D	383_Q	0.556	0.87
309_P	319_I	0.555	0.87
296_V	299_P	0.555	0.87
326_A	331_P	0.555	0.87
351_L	360_D	0.555	0.87
105_L	138_C	0.555	0.87
264_L	468_G	0.554	0.87
101_H	112_D	0.554	0.87
448_H	499_H	0.553	0.87
342_S	355_M	0.552	0.87
328_G	334_L	0.552	0.87
252_R	287_V	0.549	0.86
90_I	127_V	0.546	0.86
77_A	160_V	0.546	0.86
336_S	339_A	0.546	0.86
375_A	381_H	0.544	0.86
298_L	303_M	0.544	0.86
332_D	336_S	0.543	0.86
105_L	129_L	0.542	0.86
221_Y	225_A	0.542	0.86
101_H	443_H	0.541	0.86
69_Y	90_I	0.540	0.85
289_D	294_D	0.540	0.85
334_L	340_L	0.539	0.85
409_K	414_A	0.538	0.85
251_N	288_N	0.538	0.85
44_A	84_K	0.537	0.85
381_H	385_M	0.537	0.85
143_H	443_H	0.536	0.85
129_L	160_V	0.534	0.85
316_V	323_A	0.534	0.85
80_L	84_K	0.532	0.85
90_I	118_I	0.532	0.85
78_V	160_V	0.532	0.85
314_H	318_R	0.531	0.85
325_S	330_L	0.531	0.85
293_F	298_L	0.531	0.85
106_E	133_Q	0.529	0.84
378_G	384_M	0.528	0.84
103_H	505_H	0.528	0.84
221_Y	316_V	0.527	0.84
225_A	318_R	0.526	0.84
132_D	490_A	0.525	0.84
353_L	360_D	0.525	0.84
102_W	449_G	0.524	0.84
379_M	383_Q	0.523	0.84
343_L	353_L	0.523	0.84
131_V	134_P	0.523	0.84
348_V	356_D	0.523	0.84
137_T	180_D	0.522	0.84
347_T	353_L	0.521	0.83
368_M	375_A	0.521	0.83
498_A	514_F	0.520	0.83
354_S	358_M	0.520	0.83
456_S	482_V	0.519	0.83
410_I	445_F	0.518	0.83
167_I	177_G	0.518	0.83
382_S	385_M	0.518	0.83
405_H	410_I	0.517	0.83
369_E	373_D	0.515	0.83
101_H	499_H	0.514	0.83
320_Q	325_S	0.513	0.82
102_W	107_V	0.513	0.82
350_K	361_M	0.513	0.82
372_G	379_M	0.513	0.82
116_Q	119_I	0.513	0.82
334_L	338_P	0.513	0.82
68_G	71_G	0.512	0.82
293_F	300_V	0.512	0.82
109_G	114_G	0.512	0.82
255_Y	267_P	0.511	0.82
374_Q	379_M	0.511	0.82
310_F	318_R	0.511	0.82
346_L	354_S	0.510	0.82
341_P	349_R	0.510	0.82
214_L	300_V	0.510	0.82
362_M	365_Q	0.509	0.82
408_N	416_D	0.509	0.82
224_H	233_L	0.509	0.82
205_A	209_W	0.509	0.82
362_M	368_M	0.508	0.82
54_A	68_G	0.507	0.82
323_A	328_G	0.507	0.82
448_H	501_H	0.506	0.82
448_H	500_C	0.506	0.82
137_T	258_A	0.505	0.82
490_A	496_Y	0.504	0.81
103_H	499_H	0.504	0.81
112_D	115_P	0.503	0.81
323_A	327_S	0.503	0.81
98_T	156_L	0.501	0.81
457_E	482_V	0.500	0.81

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4e9sA	1	0.9147	100	0.209	Contact Map
1zpuA	3	0.8605	100	0.216	Contact Map
2uxtA	1	0.8043	100	0.225	Contact Map
3zx1A	1	0.874	100	0.226	Contact Map
2xu9A	1	0.8198	100	0.229	Contact Map
3gyrA	4	0.9089	100	0.233	Contact Map
3sqrA	1	0.8605	100	0.233	Contact Map
3abgA	1	0.8585	100	0.235	Contact Map
1aozA	3	0.8876	100	0.235	Contact Map
2wsdA	1	0.8643	100	0.241	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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