HOFB - ECOLI - GREMLIN Contacts

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HOFB - Protein transport protein HofB homolog

UniProt:	P36645	Sequences: MNIPQLTALCLRYHGVLLDASEEVVHVAVVDAPSHELLDALHFATTKRIEITCWTRQQMEGHASRTQQTLPVAVQEKHQPKAELLTRTLQSALEQRASDIHIEPADNAYRIRLRIDGVLHPLPDVSPDAGVALTARLKVLGNLDIAEHRLPQDGQFTVELAGNAVSFRIATLPCRGGEKVVLRLLQQVGQALDVNTLGMQPLQLADFAHALQQPQGLVLVTGPTGSGKTVTLYSALQKLNTADINICSVEDPVEIPIAGLNQTQIHPRAGLTFQGVLRALLRQDPDVIMIGEIRDGETAEIAIKAAQTGHLVLSTLHTNSTCETLVRLQQMGVARWMLSSALTLVIAQRLVRKLCPHCRRQQGEPIHIPDNVWPSPLPHWQAPGCVHCYHGFYGRTALFEVLPITPVIRQLISANTDVESLETHARQAGMRTLFENGCLAVEQGLTTFEELIRVLGMPHGE	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG12106
Length:	461 (447)
Sequences:	4625 (3196)
Seq/√Len:	151.1

ECOLI - HOFB GSPE YGGR
BACSU - COMGA
HALSA - Q9HQY3 Q9HR79
SULSO - Q97VE6 Q97WB7 Q7LXX6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
354_L	382_A	4.645	1.00
405_T	428_A	4.508	1.00
207_F	235_A	4.012	1.00
210_A	344_L	3.871	1.00
411_L	424_H	3.591	1.00
360_R	383_P	3.530	1.00
179_K	245_N	3.516	1.00
134_T	180_V	3.431	1.00
359_R	380_W	3.363	1.00
320_S	323_E	3.299	1.00
244_I	287_V	3.195	1.00
357_H	387_H	3.165	1.00
208_A	238_K	3.110	1.00
361_Q	378_P	3.007	1.00
54_W	59_M	2.834	1.00
219_L	314_S	2.721	1.00
360_R	381_Q	2.683	1.00
247_C	280_L	2.647	1.00
354_L	447_T	2.622	1.00
437_G	451_L	2.605	1.00
411_L	416_T	2.587	1.00
353_K	396_T	2.568	1.00
249_V	276_V	2.545	1.00
362_Q	381_Q	2.542	1.00
354_L	359_R	2.457	1.00
167_F	182_L	2.423	1.00
221_T	316_L	2.405	1.00
175_R	253_V	2.380	1.00
426_R	435_E	2.348	1.00
424_H	428_A	2.323	1.00
204_L	208_A	2.300	1.00
163_N	186_Q	2.286	1.00
211_L	235_A	2.283	1.00
362_Q	379_H	2.268	1.00
346_I	401_V	2.235	1.00
109_Y	130_G	2.225	1.00
150_L	269_A	2.214	1.00
24_V	50_E	2.212	1.00
405_T	424_H	2.211	1.00
172_L	263_T	2.178	1.00
404_I	412_I	2.170	1.00
85_L	133_L	2.147	1.00
396_T	445_L	2.132	1.00
436_N	440_A	2.114	1.00
209_H	403_P	2.095	1.00
28_A	54_W	2.087	1.00
293_I	302_A	2.073	1.00
424_H	427_Q	2.073	1.00
407_V	428_A	2.056	1.00
431_R	439_L	2.045	1.00
365_P	368_I	2.041	1.00
55_T	58_Q	2.036	1.00
320_S	422_E	2.032	1.00
408_I	421_L	1.995	1.00
96_R	393_Y	1.978	1.00
143_L	171_T	1.956	1.00
382_A	447_T	1.929	1.00
179_K	261_N	1.921	1.00
410_Q	414_A	1.915	1.00
20_A	47_K	1.899	1.00
121_P	124_D	1.877	1.00
239_L	287_V	1.863	1.00
170_A	283_Q	1.843	1.00
9_L	13_Y	1.840	1.00
137_L	169_I	1.814	1.00
385_C	388_C	1.791	1.00
141_G	169_I	1.780	1.00
439_L	443_Q	1.764	1.00
322_C	402_L	1.752	1.00
118_V	453_R	1.749	1.00
438_C	442_E	1.745	1.00
203_Q	399_F	1.738	1.00
185_L	255_I	1.736	1.00
118_V	352_R	1.718	1.00
201_P	205_A	1.697	1.00
355_C	358_C	1.689	1.00
167_F	184_L	1.689	1.00
325_L	342_L	1.689	1.00
29_V	51_I	1.678	1.00
26_H	52_T	1.665	1.00
171_T	180_V	1.658	1.00
203_Q	401_V	1.635	1.00
41_L	49_I	1.632	1.00
396_T	440_A	1.615	1.00
27_V	41_L	1.611	1.00
110_R	121_P	1.610	1.00
200_Q	203_Q	1.601	1.00
174_C	261_N	1.598	1.00
355_C	388_C	1.594	1.00
432_T	435_E	1.589	1.00
417_D	420_S	1.588	1.00
108_A	124_D	1.585	1.00
113_L	122_L	1.582	1.00
213_Q	343_T	1.580	1.00
202_L	431_R	1.578	1.00
416_T	420_S	1.577	1.00
355_C	385_C	1.567	1.00
357_H	393_Y	1.560	1.00
358_C	388_C	1.556	1.00
272_T	275_G	1.548	1.00
358_C	385_C	1.540	1.00
249_V	280_L	1.537	1.00
434_F	455_L	1.521	1.00
362_Q	368_I	1.513	1.00
19_D	26_H	1.509	1.00
218_V	311_L	1.495	1.00
97_A	115_I	1.489	1.00
440_A	445_L	1.487	1.00
402_L	430_M	1.481	1.00
329_Q	338_L	1.473	1.00
203_Q	436_N	1.467	1.00
364_E	379_H	1.462	1.00
193_D	196_T	1.443	1.00
199_M	399_F	1.428	1.00
356_P	359_R	1.415	1.00
266_H	269_A	1.410	1.00
361_Q	380_W	1.406	1.00
263_T	280_L	1.405	1.00
121_P	242_A	1.405	1.00
379_H	441_V	1.405	1.00
18_L	52_T	1.401	1.00
102_I	109_Y	1.399	1.00
103_E	112_R	1.376	1.00
354_L	383_P	1.376	1.00
407_V	424_H	1.359	1.00
203_Q	206_D	1.358	1.00
441_V	451_L	1.355	1.00
18_L	28_A	1.348	1.00
14_H	30_V	1.336	1.00
300_E	304_K	1.335	1.00
299_A	333_V	1.335	1.00
423_T	427_Q	1.333	1.00
354_L	380_W	1.329	1.00
414_A	420_S	1.322	1.00
14_H	60_E	1.321	1.00
25_V	45_T	1.310	1.00
118_V	243_D	1.308	1.00
115_I	120_H	1.303	1.00
30_V	59_M	1.290	1.00
10_C	63_A	1.289	1.00
31_D	34_S	1.280	1.00
224_T	285_P	1.279	1.00
205_A	209_H	1.279	1.00
85_L	137_L	1.271	1.00
329_Q	335_R	1.270	1.00
11_L	64_S	1.265	1.00
240_N	246_I	1.263	1.00
179_K	247_C	1.259	1.00
195_N	204_L	1.259	1.00
407_V	427_Q	1.248	1.00
14_H	56_R	1.247	1.00
218_V	344_L	1.246	1.00
202_L	206_D	1.245	1.00
223_P	349_R	1.229	1.00
239_L	313_L	1.225	1.00
221_T	318_T	1.222	1.00
392_F	446_T	1.219	1.00
195_N	208_A	1.214	1.00
293_I	314_S	1.208	1.00
276_V	280_L	1.206	1.00
422_E	426_R	1.206	1.00
16_V	59_M	1.201	1.00
212_Q	238_K	1.201	1.00
35_H	39_D	1.196	1.00
224_T	310_H	1.196	1.00
206_D	403_P	1.195	1.00
406_P	409_R	1.194	1.00
425_A	430_M	1.187	1.00
199_M	207_F	1.185	1.00
199_M	231_T	1.180	1.00
209_H	213_Q	1.180	1.00
303_I	333_V	1.180	1.00
381_Q	449_E	1.176	1.00
210_A	401_V	1.166	1.00
38_L	51_I	1.155	1.00
158_V	167_F	1.151	1.00
322_C	421_L	1.146	1.00
91_S	95_Q	1.142	1.00
219_L	293_I	1.135	1.00
156_F	167_F	1.123	0.99
392_F	447_T	1.121	0.99
18_L	26_H	1.118	0.99
408_I	425_A	1.118	0.99
377_L	442_E	1.111	0.99
364_E	369_P	1.096	0.99
93_L	165_V	1.092	0.99
140_L	156_F	1.089	0.99
23_E	47_K	1.082	0.99
240_N	259_G	1.081	0.99
217_L	312_V	1.079	0.99
366_I	370_D	1.076	0.99
426_R	430_M	1.068	0.99
426_R	432_T	1.062	0.99
307_Q	337_M	1.061	0.99
16_V	62_H	1.058	0.99
15_G	27_V	1.057	0.99
420_S	423_T	1.053	0.99
345_V	402_L	1.051	0.99
324_T	345_V	1.047	0.99
26_H	50_E	1.044	0.99
316_L	324_T	1.043	0.99
61_G	65_R	1.043	0.99
358_C	384_G	1.040	0.99
153_D	170_A	1.040	0.99
231_T	348_Q	1.039	0.99
442_E	445_L	1.034	0.99
200_Q	439_L	1.034	0.99
446_T	450_E	1.031	0.99
165_V	184_L	1.028	0.99
304_K	307_Q	1.025	0.99
347_A	433_L	1.016	0.99
211_L	218_V	1.014	0.99
232_L	289_M	1.013	0.99
159_E	164_A	1.011	0.99
278_R	297_E	1.011	0.99
28_A	52_T	1.009	0.99
322_C	422_E	1.006	0.99
438_C	441_V	1.006	0.99
200_Q	443_Q	1.001	0.99
342_L	345_V	1.000	0.99
138_K	178_E	0.998	0.99
203_Q	346_I	0.995	0.99
398_L	437_G	0.990	0.99
441_V	448_F	0.988	0.99
384_G	388_C	0.988	0.99
425_A	429_G	0.986	0.99
296_G	300_E	0.985	0.99
105_A	110_R	0.981	0.99
439_L	442_E	0.981	0.99
288_I	305_A	0.975	0.99
114_R	284_D	0.970	0.99
351_V	446_T	0.966	0.98
164_A	187_Q	0.964	0.98
80_P	83_E	0.961	0.98
38_L	42_H	0.961	0.98
199_M	397_A	0.959	0.98
59_M	63_A	0.956	0.98
210_A	343_T	0.954	0.98
56_R	60_E	0.953	0.98
376_P	379_H	0.950	0.98
280_L	288_I	0.939	0.98
210_A	218_V	0.939	0.98
239_L	246_I	0.939	0.98
304_K	330_Q	0.935	0.98
292_E	317_H	0.935	0.98
116_D	352_R	0.934	0.98
169_I	182_L	0.933	0.98
220_V	231_T	0.933	0.98
200_Q	440_A	0.932	0.98
352_R	450_E	0.923	0.98
88_T	111_I	0.921	0.98
322_C	430_M	0.920	0.98
438_C	448_F	0.919	0.98
215_Q	320_S	0.917	0.98
96_R	115_I	0.911	0.98
127_P	130_G	0.910	0.98
274_Q	297_E	0.904	0.98
263_T	276_V	0.904	0.98
247_C	261_N	0.904	0.98
241_T	244_I	0.902	0.98
221_T	324_T	0.901	0.98
364_E	368_I	0.901	0.98
170_A	181_V	0.897	0.98
150_L	271_L	0.894	0.97
10_C	15_G	0.890	0.97
179_K	283_Q	0.882	0.97
211_L	313_L	0.881	0.97
363_G	378_P	0.877	0.97
92_A	113_L	0.877	0.97
68_Q	72_V	0.876	0.97
200_Q	436_N	0.875	0.97
398_L	455_L	0.874	0.97
245_N	261_N	0.873	0.97
378_P	381_Q	0.870	0.97
15_G	41_L	0.866	0.97
42_H	48_R	0.861	0.97
165_V	186_Q	0.860	0.97
82_A	136_R	0.856	0.97
329_Q	415_N	0.855	0.97
253_V	264_Q	0.852	0.97
220_V	346_I	0.851	0.97
247_C	263_T	0.849	0.97
240_N	243_D	0.848	0.97
249_V	265_I	0.845	0.96
338_L	342_L	0.845	0.96
13_Y	37_L	0.844	0.96
293_I	299_A	0.844	0.96
136_R	140_L	0.844	0.96
353_K	445_L	0.843	0.96
254_E	317_H	0.842	0.96
351_V	398_L	0.839	0.96
29_V	34_S	0.838	0.96
32_A	53_C	0.837	0.96
440_A	443_Q	0.837	0.96
108_A	258_A	0.836	0.96
410_Q	423_T	0.832	0.96
282_R	292_E	0.831	0.96
270_G	275_G	0.825	0.96
40_A	43_F	0.821	0.96
30_V	56_R	0.821	0.96
267_P	271_L	0.821	0.96
411_L	420_S	0.820	0.96
88_T	102_I	0.813	0.96
228_K	317_H	0.813	0.96
190_Q	193_D	0.807	0.95
436_N	439_L	0.804	0.95
143_L	180_V	0.803	0.95
335_R	415_N	0.801	0.95
181_V	283_Q	0.800	0.95
228_K	292_E	0.799	0.95
282_R	317_H	0.797	0.95
88_T	100_I	0.791	0.95
99_D	317_H	0.790	0.95
339_S	413_S	0.788	0.95
294_R	317_H	0.788	0.95
404_I	409_R	0.787	0.95
447_T	450_E	0.786	0.95
249_V	263_T	0.786	0.95
355_C	384_G	0.786	0.95
194_V	208_A	0.785	0.95
90_Q	94_E	0.785	0.95
95_Q	389_Y	0.785	0.95
25_V	47_K	0.782	0.95
13_Y	40_A	0.781	0.95
45_T	48_R	0.779	0.94
207_F	401_V	0.778	0.94
361_Q	364_E	0.777	0.94
95_Q	120_H	0.772	0.94
34_S	37_L	0.770	0.94
303_I	337_M	0.769	0.94
325_L	412_I	0.768	0.94
215_Q	343_T	0.767	0.94
144_D	268_R	0.767	0.94
277_L	301_I	0.767	0.94
30_V	33_P	0.765	0.94
402_L	408_I	0.763	0.94
408_I	424_H	0.763	0.94
300_E	334_A	0.759	0.94
398_L	454_V	0.758	0.94
89_L	167_F	0.757	0.94
404_I	408_I	0.756	0.94
175_R	256_P	0.755	0.93
379_H	382_A	0.754	0.93
421_L	425_A	0.752	0.93
431_R	435_E	0.752	0.93
426_R	429_G	0.752	0.93
170_A	279_A	0.751	0.93
74_V	77_K	0.750	0.93
388_C	391_G	0.750	0.93
448_F	452_I	0.749	0.93
60_E	63_A	0.748	0.93
30_V	54_W	0.748	0.93
15_G	37_L	0.746	0.93
23_E	26_H	0.746	0.93
416_T	421_L	0.746	0.93
434_F	437_G	0.745	0.93
398_L	440_A	0.744	0.93
93_L	160_L	0.740	0.93
221_T	347_A	0.740	0.93
210_A	403_P	0.740	0.93
37_L	41_L	0.738	0.93
254_E	292_E	0.738	0.93
282_R	294_R	0.737	0.93
385_C	391_G	0.736	0.93
93_L	184_L	0.735	0.93
101_H	181_V	0.734	0.92
315_T	318_T	0.731	0.92
232_L	313_L	0.730	0.92
291_G	317_H	0.727	0.92
29_V	38_L	0.725	0.92
62_H	65_R	0.724	0.92
229_T	233_Y	0.724	0.92
99_D	282_R	0.723	0.92
99_D	228_K	0.722	0.92
369_P	377_L	0.719	0.92
339_S	412_I	0.718	0.92
322_C	418_V	0.717	0.92
172_L	283_Q	0.716	0.92
106_D	176_G	0.716	0.92
166_S	187_Q	0.713	0.91
233_Y	257_I	0.712	0.91
229_T	257_I	0.711	0.91
99_D	292_E	0.710	0.91
137_L	180_V	0.709	0.91
410_Q	419_E	0.708	0.91
237_Q	240_N	0.705	0.91
245_N	283_Q	0.703	0.91
194_V	234_S	0.702	0.91
406_P	419_E	0.701	0.91
407_V	411_L	0.701	0.91
450_E	453_R	0.701	0.91
28_A	59_M	0.700	0.91
446_T	451_L	0.700	0.91
29_V	37_L	0.700	0.91
194_V	204_L	0.699	0.91
101_H	284_D	0.698	0.90
84_L	88_T	0.696	0.90
281_L	305_A	0.695	0.90
202_L	439_L	0.695	0.90
310_H	327_R	0.695	0.90
220_V	232_L	0.692	0.90
156_F	169_I	0.688	0.90
318_T	321_T	0.688	0.90
217_L	302_A	0.687	0.90
418_V	422_E	0.687	0.90
229_T	255_I	0.685	0.90
254_E	294_R	0.684	0.90
272_T	297_E	0.683	0.90
437_G	440_A	0.683	0.90
17_L	20_A	0.679	0.89
60_E	64_S	0.677	0.89
420_S	424_H	0.676	0.89
186_Q	190_Q	0.674	0.89
89_L	100_I	0.673	0.89
271_L	276_V	0.672	0.89
231_T	346_I	0.672	0.89
103_E	148_H	0.670	0.89
202_L	205_A	0.669	0.89
352_R	392_F	0.669	0.89
186_Q	189_G	0.666	0.88
215_Q	319_N	0.666	0.88
82_A	86_T	0.663	0.88
203_Q	431_R	0.661	0.88
15_G	29_V	0.661	0.88
115_I	122_L	0.659	0.88
31_D	37_L	0.658	0.88
130_G	134_T	0.658	0.88
407_V	410_Q	0.656	0.88
218_V	343_T	0.655	0.88
224_T	286_D	0.655	0.88
267_P	272_T	0.654	0.87
280_L	290_I	0.652	0.87
102_I	130_G	0.651	0.87
228_K	254_E	0.649	0.87
99_D	254_E	0.648	0.87
22_E	47_K	0.648	0.87
183_R	317_H	0.647	0.87
344_L	401_V	0.647	0.87
374_P	377_L	0.647	0.87
191_A	237_Q	0.647	0.87
10_C	17_L	0.645	0.87
150_L	275_G	0.643	0.87
172_L	280_L	0.642	0.86
168_R	252_P	0.639	0.86
403_P	430_M	0.639	0.86
354_L	360_R	0.639	0.86
206_D	209_H	0.637	0.86
86_T	136_R	0.637	0.86
144_D	149_R	0.635	0.86
218_V	346_I	0.632	0.86
406_P	423_T	0.632	0.86
330_Q	413_S	0.631	0.86
333_V	338_L	0.630	0.85
278_R	295_D	0.628	0.85
143_L	169_I	0.628	0.85
183_R	292_E	0.627	0.85
402_L	421_L	0.626	0.85
21_S	26_H	0.626	0.85
9_L	44_A	0.626	0.85
228_K	282_R	0.625	0.85
437_G	441_V	0.625	0.85
20_A	23_E	0.625	0.85
452_I	455_L	0.624	0.85
21_S	24_V	0.624	0.85
228_K	294_R	0.622	0.85
85_L	140_L	0.621	0.85
58_Q	61_G	0.621	0.85
20_A	25_V	0.621	0.85
380_W	383_P	0.620	0.85
163_N	188_V	0.620	0.85
138_K	152_Q	0.620	0.85
363_G	376_P	0.619	0.84
438_C	451_L	0.619	0.84
374_P	378_P	0.618	0.84
99_D	294_R	0.616	0.84
299_A	328_L	0.616	0.84
318_T	324_T	0.616	0.84
326_V	418_V	0.615	0.84
183_R	294_R	0.615	0.84
126_S	129_A	0.615	0.84
183_R	254_E	0.612	0.84
141_G	156_F	0.612	0.84
108_A	121_P	0.611	0.84
375_S	378_P	0.610	0.84
105_A	108_A	0.609	0.83
21_S	50_E	0.606	0.83
99_D	252_P	0.606	0.83
137_L	182_L	0.604	0.83
224_T	308_T	0.603	0.83
45_T	49_I	0.603	0.83
364_E	377_L	0.602	0.83
437_G	446_T	0.601	0.83
285_P	310_H	0.601	0.83
224_T	282_R	0.600	0.83
183_R	282_R	0.600	0.83
73_A	76_E	0.600	0.83
208_A	212_Q	0.599	0.82
42_H	49_I	0.599	0.82
214_P	319_N	0.597	0.82
155_Q	166_S	0.594	0.82
57_Q	61_G	0.593	0.82
403_P	406_P	0.592	0.82
135_A	145_I	0.591	0.82
431_R	436_N	0.591	0.82
201_P	204_L	0.590	0.81
36_E	39_D	0.590	0.81
222_G	291_G	0.589	0.81
249_V	301_I	0.588	0.81
367_H	370_D	0.586	0.81
103_E	261_N	0.586	0.81
296_G	332_G	0.584	0.81
273_F	298_T	0.583	0.81
277_L	280_L	0.580	0.80
438_C	455_L	0.579	0.80
252_P	292_E	0.578	0.80
207_F	346_I	0.578	0.80
158_V	184_L	0.578	0.80
379_H	442_E	0.578	0.80
349_R	433_L	0.577	0.80
39_D	42_H	0.576	0.80
224_T	292_E	0.575	0.80
143_L	170_A	0.573	0.80
239_L	244_I	0.573	0.80
224_T	294_R	0.572	0.79
210_A	346_I	0.571	0.79
378_P	382_A	0.571	0.79
228_K	291_G	0.570	0.79
91_S	113_L	0.570	0.79
254_E	282_R	0.569	0.79
366_I	369_P	0.569	0.79
157_T	167_F	0.569	0.79
41_L	45_T	0.568	0.79
351_V	396_T	0.568	0.79
357_H	386_V	0.567	0.79
416_T	424_H	0.567	0.79
288_I	310_H	0.566	0.79
99_D	183_R	0.565	0.79
157_T	164_A	0.565	0.79
295_D	298_T	0.565	0.79
269_A	275_G	0.565	0.79
99_D	168_R	0.564	0.79
31_D	53_C	0.562	0.78
339_S	343_T	0.562	0.78
222_G	226_S	0.561	0.78
362_Q	365_P	0.560	0.78
101_H	119_L	0.559	0.78
138_K	154_G	0.558	0.78
435_E	438_C	0.557	0.78
236_L	289_M	0.556	0.78
94_E	161_A	0.556	0.78
109_Y	133_L	0.554	0.77
183_R	228_K	0.552	0.77
369_P	376_P	0.552	0.77
356_P	387_H	0.550	0.77
172_L	279_A	0.550	0.77
419_E	423_T	0.550	0.77
9_L	12_R	0.550	0.77
13_Y	34_S	0.549	0.77
252_P	317_H	0.547	0.76
331_M	399_F	0.546	0.76
308_T	319_N	0.546	0.76
61_G	64_S	0.546	0.76
9_L	15_G	0.545	0.76
23_E	48_R	0.545	0.76
29_V	32_A	0.545	0.76
303_I	341_A	0.544	0.76
193_D	238_K	0.543	0.76
22_E	50_E	0.543	0.76
308_T	327_R	0.542	0.76
217_L	344_L	0.542	0.76
75_Q	78_H	0.542	0.76
112_R	261_N	0.541	0.76
187_Q	255_I	0.540	0.76
47_K	51_I	0.540	0.76
176_G	256_P	0.539	0.75
308_T	317_H	0.538	0.75
230_V	255_I	0.538	0.75
322_C	400_E	0.536	0.75
168_R	317_H	0.534	0.75
307_Q	341_A	0.534	0.75
102_I	111_I	0.533	0.75
67_Q	71_P	0.532	0.74
251_D	264_Q	0.532	0.74
169_I	180_V	0.532	0.74
224_T	317_H	0.532	0.74
322_C	326_V	0.532	0.74
95_Q	115_I	0.531	0.74
368_I	449_E	0.531	0.74
109_Y	134_T	0.531	0.74
292_E	327_R	0.530	0.74
116_D	353_K	0.530	0.74
144_D	150_L	0.530	0.74
70_L	73_A	0.530	0.74
110_R	124_D	0.529	0.74
433_L	437_G	0.529	0.74
98_S	395_R	0.529	0.74
367_H	371_N	0.529	0.74
130_G	180_V	0.528	0.74
197_L	399_F	0.528	0.74
84_L	133_L	0.527	0.74
110_R	242_A	0.526	0.74
111_I	125_V	0.526	0.74
318_T	347_A	0.526	0.74
107_N	258_A	0.526	0.74
150_L	270_G	0.526	0.74
217_L	303_I	0.525	0.73
323_E	418_V	0.524	0.73
257_I	260_L	0.524	0.73
52_T	58_Q	0.524	0.73
254_E	291_G	0.524	0.73
291_G	309_G	0.524	0.73
86_T	140_L	0.524	0.73
407_V	414_A	0.523	0.73
195_N	238_K	0.523	0.73
434_F	438_C	0.523	0.73
29_V	36_E	0.523	0.73
99_D	273_F	0.522	0.73
21_S	25_V	0.522	0.73
354_L	361_Q	0.522	0.73
68_Q	71_P	0.522	0.73
215_Q	455_L	0.521	0.73
409_R	419_E	0.521	0.73
361_Q	377_L	0.520	0.73
18_L	25_V	0.520	0.73
269_A	272_T	0.520	0.73
360_R	363_G	0.520	0.73
34_S	40_A	0.519	0.73
357_H	448_F	0.519	0.73
292_E	315_T	0.518	0.73
101_H	114_R	0.518	0.73
145_I	149_R	0.517	0.72
159_E	162_G	0.517	0.72
97_A	113_L	0.516	0.72
303_I	307_Q	0.516	0.72
240_N	244_I	0.515	0.72
434_F	451_L	0.515	0.72
360_R	382_A	0.515	0.72
98_S	181_V	0.513	0.72
68_Q	76_E	0.512	0.72
101_H	168_R	0.512	0.72
254_E	327_R	0.512	0.72
418_V	421_L	0.512	0.72
168_R	254_E	0.512	0.72
139_V	145_I	0.511	0.71
29_V	44_A	0.510	0.71
317_H	327_R	0.510	0.71
129_A	133_L	0.509	0.71
155_Q	249_V	0.509	0.71
359_R	378_P	0.508	0.71
57_Q	60_E	0.508	0.71
22_E	48_R	0.507	0.71
91_S	94_E	0.507	0.71
72_V	86_T	0.506	0.71
87_R	91_S	0.506	0.71
173_P	319_N	0.505	0.71
10_C	13_Y	0.505	0.71
323_E	326_V	0.505	0.71
24_V	48_R	0.505	0.71
170_A	179_K	0.505	0.71
139_V	245_N	0.504	0.70
10_C	330_Q	0.504	0.70
222_G	309_G	0.503	0.70
99_D	291_G	0.503	0.70
207_F	218_V	0.502	0.70
200_Q	431_R	0.501	0.70
381_Q	407_V	0.501	0.70
422_E	432_T	0.501	0.70
152_Q	178_E	0.501	0.70
34_S	38_L	0.500	0.70
274_Q	279_A	0.500	0.70

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4phtA	1	0.9349	100	0.259	Contact Map
4ksrA	3	0.7896	100	0.335	Contact Map
1p9rA	1	0.8156	100	0.358	Contact Map
2ewvA	3	0.7072	100	0.52	Contact Map
3jvvA	3	0.6985	100	0.531	Contact Map
2oap1	3	0.9371	100	0.564	Contact Map
4ihqA	3	0.9436	100	0.606	Contact Map
2eyuA	1	0.4924	100	0.658	Contact Map
4bloA	4	0.5618	100	0.716	Contact Map
2gzaA	3	0.6247	100	0.722	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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