YOJI - ECOLI - GREMLIN Contacts

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YOJI - ABC transporter ATP-binding protein YojI

UniProt:	P33941	Sequences: MELLVLVWRQYRWPFISVMALSLASAALGIGLIAFINQRLIETADTSLLVLPEFLGLLLLLMAVTLGSQLALTTLGHHFVYRLRSEFIKRILDTHVERIEQLGSASLLAGLTSDVRNITIAFVRLPELVQGIILTIGSAAYLWMLSGKMLLVTAIWMAITIWGGFVLVARVYKHMATLRETEDKLYTDFQTVLEGRKELTLNRERAEYVFNNLYIPDAQEYRHHIIRADTFHLSAVNWSNIMMLGAIGLVFWMANSLGWADTNVAATYSLTLLFLRTPLLSAVGALPTLLTAQVAFNKLNKFALAPFKAEFPRPQAFPNWQTLELRNVTFAYQDNAFSVGPINLTIKRGELLFLIGGNGSGKSTLAMLLTGLYQPQSGEILLDGKPVSGEQPEDYRKLFSAVFTDVWLFDQLLGPEGKPANPQLVEKWLAQLKMAHKLELSNGRIVNLKLSKGQKKRVALLLALAEERDIILLDEWAADQDPHFRREFYQVLLPLMQEMGKTIFAISHDDHYFIHADRLLEMRNGQLSELTGEERDAASRDAVARTA	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG12070
Length:	547 (528)
Sequences:	52528 (37343)
Seq/√Len:	1625.1

ECOLI - YOJI MSBA MDLB MDLA CYDC CYDD YDDA MACB PROV ARAG RBSA POTG MALK POTA LSRA CYSA YCJV FBPC UGPC
BACSU - YHEH SUNT YGAD BMRA YFIC YWJA YFIB YHEI YKNU YKNV CYDD CYDC YVRA OPUAA TAGH OPUCA OPUBA MSMX RBSA YURJ
HALSA - Q9HSQ7 Q9HMW0 Q9HMX3 BTUDA Q9HHQ5 Q9HR06 Q9HNZ9 Q9HMX2
SULSO - Q97UJ9 Q97VF5 Q97UF2 Q97VK9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
435_A	444_R	4.589	1.00
350_E	518_R	4.512	1.00
324_E	345_T	4.496	1.00
327_N	341_P	4.485	1.00
347_K	350_E	4.376	1.00
411_Q	415_P	4.063	1.00
326_R	379_E	4.042	1.00
518_R	530_L	4.030	1.00
430_A	435_A	3.867	1.00
414_G	422_P	3.778	1.00
326_R	381_L	3.517	1.00
379_E	386_P	3.458	1.00
322_T	345_T	3.448	1.00
340_G	526_Q	3.195	1.00
325_L	328_V	3.155	1.00
422_P	426_E	3.056	1.00
414_G	418_K	3.054	1.00
414_G	445_I	3.023	1.00
366_A	506_I	2.935	1.00
337_F	340_G	2.893	1.00
329_T	341_P	2.886	1.00
429_L	444_R	2.840	1.00
366_A	472_L	2.748	1.00
398_L	469_D	2.659	1.00
529_E	539_S	2.612	1.00
421_N	424_L	2.598	1.00
324_E	381_L	2.567	1.00
427_K	431_Q	2.509	1.00
426_E	435_A	2.494	1.00
322_T	347_K	2.493	1.00
346_I	352_L	2.464	1.00
417_G	429_L	2.443	1.00
467_E	501_K	2.422	1.00
331_A	337_F	2.406	1.00
140_A	144_M	2.400	1.00
371_G	374_Q	2.397	1.00
520_L	530_L	2.393	1.00
391_Q	394_D	2.385	1.00
532_G	535_R	2.372	1.00
400_S	468_R	2.367	1.00
329_T	337_F	2.298	1.00
442_N	446_V	2.276	1.00
529_E	540_R	2.257	1.00
329_T	377_S	2.240	1.00
426_E	430_A	2.237	1.00
344_L	520_L	2.236	1.00
41_I	263_N	2.236	1.00
529_E	541_D	2.233	1.00
414_G	425_V	2.231	1.00
351_L	516_A	2.206	1.00
322_T	348_R	2.170	1.00
41_I	261_D	2.155	1.00
434_M	437_K	2.131	1.00
417_G	425_V	2.091	1.00
325_L	344_L	2.074	1.00
493_L	515_H	2.062	1.00
485_R	509_D	2.038	1.00
327_N	343_N	2.034	1.00
321_Q	383_D	2.001	1.00
300_N	304_L	1.997	1.00
346_I	504_F	1.991	1.00
424_L	467_E	1.986	1.00
374_Q	388_S	1.975	1.00
11_Y	82_R	1.950	1.00
331_A	376_Q	1.932	1.00
90_R	307_F	1.928	1.00
531_T	535_R	1.924	1.00
9_R	12_R	1.907	1.00
428_W	432_L	1.895	1.00
181_T	220_E	1.859	1.00
352_L	518_R	1.857	1.00
427_K	430_A	1.840	1.00
48_L	52_P	1.839	1.00
486_R	490_Q	1.793	1.00
443_G	446_V	1.778	1.00
352_L	520_L	1.775	1.00
365_L	522_M	1.775	1.00
418_K	425_V	1.753	1.00
520_L	527_L	1.744	1.00
418_K	422_P	1.742	1.00
146_S	257_L	1.734	1.00
353_F	516_A	1.710	1.00
311_F	391_Q	1.706	1.00
422_P	445_I	1.706	1.00
252_W	256_S	1.692	1.00
523_R	528_S	1.687	1.00
480_Q	488_F	1.680	1.00
323_L	504_F	1.679	1.00
204_E	207_E	1.673	1.00
52_P	56_G	1.671	1.00
320_W	383_D	1.665	1.00
350_E	517_D	1.663	1.00
386_P	389_G	1.661	1.00
431_Q	494_P	1.655	1.00
114_D	298_K	1.650	1.00
424_L	465_A	1.645	1.00
433_K	487_E	1.640	1.00
417_G	465_A	1.632	1.00
176_A	297_N	1.621	1.00
351_L	505_A	1.619	1.00
322_T	383_D	1.588	1.00
354_L	365_L	1.586	1.00
354_L	520_L	1.554	1.00
93_D	307_F	1.548	1.00
339_V	342_I	1.539	1.00
426_E	444_R	1.528	1.00
514_I	534_E	1.517	1.00
535_R	539_S	1.504	1.00
507_S	512_Y	1.501	1.00
424_L	427_K	1.500	1.00
423_Q	426_E	1.481	1.00
347_K	518_R	1.471	1.00
422_P	425_V	1.462	1.00
370_T	401_A	1.449	1.00
143_W	150_L	1.444	1.00
330_F	364_T	1.444	1.00
368_L	380_I	1.432	1.00
90_R	94_T	1.427	1.00
37_N	267_T	1.423	1.00
429_L	438_L	1.417	1.00
429_L	435_A	1.414	1.00
437_K	454_Q	1.412	1.00
49_L	53_E	1.411	1.00
184_K	220_E	1.406	1.00
341_P	526_Q	1.400	1.00
357_G	523_R	1.393	1.00
328_V	375_P	1.390	1.00
490_Q	494_P	1.368	1.00
534_E	538_A	1.362	1.00
330_F	368_L	1.355	1.00
330_F	373_Y	1.354	1.00
400_S	463_A	1.342	1.00
188_D	217_D	1.335	1.00
325_L	369_L	1.335	1.00
319_N	383_D	1.333	1.00
434_M	438_L	1.330	1.00
519_L	533_E	1.319	1.00
33_I	271_T	1.314	1.00
143_W	147_G	1.301	1.00
321_Q	348_R	1.296	1.00
208_Y	419_P	1.294	1.00
494_P	499_M	1.293	1.00
177_T	224_H	1.293	1.00
170_R	173_K	1.277	1.00
353_F	513_F	1.273	1.00
426_E	429_L	1.267	1.00
358_N	484_F	1.265	1.00
90_R	303_A	1.263	1.00
533_E	537_A	1.260	1.00
413_L	458_V	1.248	1.00
329_T	340_G	1.241	1.00
375_P	387_V	1.241	1.00
326_R	343_N	1.234	1.00
181_T	184_K	1.228	1.00
496_M	503_I	1.227	1.00
312_P	389_G	1.220	1.00
369_L	504_F	1.214	1.00
162_W	166_V	1.213	1.00
10_Q	82_R	1.213	1.00
352_L	504_F	1.212	1.00
322_T	384_G	1.207	1.00
392_P	396_R	1.203	1.00
423_Q	427_K	1.201	1.00
261_D	264_V	1.200	1.00
149_M	268_Y	1.199	1.00
30_I	137_G	1.199	1.00
195_G	407_W	1.198	1.00
181_T	224_H	1.196	1.00
214_Y	218_A	1.194	1.00
21_L	64_V	1.189	1.00
385_K	389_G	1.179	1.00
192_V	208_Y	1.178	1.00
200_T	205_R	1.176	1.00
212_N	216_P	1.174	1.00
37_N	41_I	1.169	1.00
348_R	469_D	1.169	1.00
342_I	365_L	1.163	1.00
431_Q	464_L	1.161	1.00
432_L	461_L	1.159	1.00
344_L	365_L	1.158	1.00
441_S	446_V	1.158	1.00
219_Q	223_H	1.157	1.00
85_S	89_K	1.152	1.00
100_E	373_Y	1.147	1.00
327_N	377_S	1.139	1.00
456_K	478_A	1.137	1.00
450_L	458_V	1.127	1.00
320_W	348_R	1.126	1.00
206_A	212_N	1.124	1.00
34_A	38_Q	1.120	1.00
440_L	446_V	1.120	1.00
346_I	502_T	1.119	1.00
429_L	434_M	1.118	1.00
142_L	268_Y	1.116	1.00
325_L	380_I	1.112	1.00
45_D	49_L	1.110	1.00
253_M	257_L	1.108	1.00
385_K	390_E	1.103	1.00
337_F	376_Q	1.103	1.00
507_S	513_F	1.102	1.00
311_F	392_P	1.100	1.00
87_F	302_F	1.098	1.00
102_L	106_S	1.095	1.00
296_F	300_N	1.091	1.00
428_W	464_L	1.091	1.00
100_E	367_M	1.078	1.00
452_K	457_R	1.076	1.00
433_K	484_F	1.076	1.00
415_P	418_K	1.074	1.00
103_G	106_S	1.072	1.00
90_R	93_D	1.072	1.00
351_L	503_I	1.069	1.00
439_E	454_Q	1.067	1.00
24_A	64_V	1.066	1.00
89_K	93_D	1.064	1.00
222_R	226_I	1.064	1.00
442_N	445_I	1.062	1.00
106_S	183_D	1.061	1.00
174_H	227_R	1.057	1.00
74_T	78_H	1.052	1.00
402_V	463_A	1.046	1.00
16_I	20_A	1.046	1.00
505_A	516_A	1.039	1.00
184_K	217_D	1.031	1.00
332_Y	338_S	1.031	1.00
323_L	369_L	1.029	1.00
325_L	365_L	1.028	1.00
147_G	151_L	1.028	1.00
469_D	501_K	1.026	1.00
406_V	459_A	1.022	1.00
151_L	155_I	1.022	1.00
368_L	375_P	1.020	1.00
38_Q	42_E	1.019	1.00
471_I	501_K	1.019	1.00
394_D	397_K	1.018	1.00
425_V	444_R	1.017	1.00
438_L	444_R	1.014	1.00
437_K	440_L	1.014	1.00
117_N	295_A	1.014	1.00
382_L	395_Y	1.013	1.00
204_E	208_Y	1.010	1.00
433_K	494_P	1.007	1.00
433_K	491_V	1.007	1.00
82_R	86_E	1.006	1.00
136_I	140_A	1.003	1.00
328_V	368_L	1.003	1.00
475_E	508_H	1.002	1.00
425_V	428_W	0.997	1.00
433_K	490_Q	0.995	1.00
148_K	259_W	0.993	1.00
199_L	208_Y	0.992	1.00
436_H	439_E	0.992	1.00
463_A	471_I	0.982	1.00
350_E	530_L	0.981	1.00
358_N	457_R	0.979	1.00
427_K	467_E	0.978	1.00
380_I	387_V	0.976	1.00
213_L	217_D	0.974	1.00
227_R	230_T	0.973	1.00
14_P	74_T	0.973	1.00
215_I	219_Q	0.973	1.00
337_F	377_S	0.973	1.00
353_F	507_S	0.972	1.00
188_D	213_L	0.972	1.00
208_Y	213_L	0.971	1.00
216_P	220_E	0.971	1.00
414_G	426_E	0.970	1.00
487_E	490_Q	0.964	1.00
331_A	338_S	0.958	1.00
324_E	384_G	0.956	1.00
219_Q	222_R	0.956	1.00
35_F	50_V	0.954	1.00
21_L	67_G	0.948	1.00
441_S	444_R	0.947	1.00
95_H	308_K	0.946	1.00
166_V	170_R	0.946	1.00
37_N	264_V	0.943	1.00
418_K	421_N	0.942	1.00
323_L	382_L	0.942	1.00
254_A	257_L	0.942	1.00
324_E	343_N	0.941	1.00
522_M	527_L	0.940	1.00
12_R	16_I	0.940	1.00
176_A	180_E	0.936	1.00
98_R	102_L	0.935	1.00
363_S	367_M	0.932	1.00
156_W	246_A	0.932	1.00
509_D	512_Y	0.931	1.00
390_E	395_Y	0.931	1.00
163_G	238_W	0.930	1.00
382_L	470_I	0.927	1.00
56_G	60_L	0.927	1.00
370_T	472_L	0.926	1.00
460_L	473_L	0.925	1.00
341_P	377_S	0.924	1.00
145_L	264_V	0.922	1.00
425_V	465_A	0.921	1.00
414_G	444_R	0.921	1.00
483_H	487_E	0.919	1.00
18_V	72_L	0.919	1.00
402_V	460_L	0.917	1.00
428_W	465_A	0.916	1.00
360_S	522_M	0.914	1.00
293_Q	297_N	0.913	1.00
49_L	52_P	0.909	1.00
477_A	488_F	0.909	1.00
114_D	295_A	0.909	1.00
220_E	224_H	0.908	1.00
371_G	392_P	0.907	1.00
13_W	17_S	0.904	1.00
86_E	90_R	0.903	1.00
177_T	181_T	0.903	1.00
81_Y	85_S	0.901	1.00
110_G	301_K	0.900	1.00
375_P	388_S	0.899	1.00
431_Q	495_L	0.897	1.00
316_A	319_N	0.892	1.00
253_M	256_S	0.892	1.00
21_L	71_A	0.891	1.00
142_L	150_L	0.888	1.00
535_R	538_A	0.887	1.00
417_G	458_V	0.887	1.00
207_E	213_L	0.887	1.00
379_E	388_S	0.886	1.00
394_D	398_L	0.885	1.00
370_T	399_F	0.882	1.00
97_E	308_K	0.882	1.00
318_P	383_D	0.879	1.00
408_L	455_K	0.878	1.00
170_R	231_F	0.876	1.00
527_L	530_L	0.873	1.00
375_P	380_I	0.870	1.00
424_L	428_W	0.868	1.00
353_F	519_L	0.867	1.00
351_L	496_M	0.866	1.00
523_R	526_Q	0.866	1.00
351_L	493_L	0.864	1.00
170_R	174_H	0.863	1.00
263_N	267_T	0.861	1.00
408_L	458_V	0.859	1.00
87_F	111_L	0.859	1.00
348_R	383_D	0.857	1.00
174_H	224_H	0.854	1.00
387_V	395_Y	0.853	1.00
434_M	439_E	0.852	1.00
331_A	334_D	0.851	1.00
139_A	150_L	0.850	1.00
326_R	345_T	0.846	1.00
393_E	397_K	0.844	1.00
177_T	227_R	0.843	1.00
306_P	310_E	0.843	1.00
533_E	536_D	0.841	1.00
496_M	499_M	0.840	1.00
11_Y	78_H	0.836	1.00
207_E	212_N	0.836	1.00
468_R	501_K	0.836	1.00
409_F	416_E	0.828	1.00
197_K	367_M	0.827	1.00
254_A	265_A	0.827	1.00
316_A	390_E	0.827	1.00
434_M	458_V	0.826	1.00
141_Y	145_L	0.825	1.00
342_I	527_L	0.824	1.00
217_D	220_E	0.819	1.00
331_A	335_N	0.819	1.00
381_L	384_G	0.815	1.00
471_I	496_M	0.815	1.00
148_K	257_L	0.813	1.00
226_I	230_T	0.813	1.00
161_I	165_F	0.812	1.00
28_L	64_V	0.809	1.00
87_F	299_L	0.809	1.00
412_L	415_P	0.808	1.00
38_Q	41_I	0.808	1.00
46_T	49_L	0.808	1.00
456_K	479_D	0.807	1.00
431_Q	435_A	0.806	1.00
18_V	75_L	0.805	1.00
390_E	394_D	0.804	1.00
489_Y	507_S	0.803	1.00
329_T	376_Q	0.802	1.00
173_K	177_T	0.802	1.00
213_L	216_P	0.802	1.00
196_R	200_T	0.802	1.00
94_T	305_A	0.802	1.00
34_A	141_Y	0.802	1.00
314_P	389_G	0.802	1.00
97_E	101_Q	0.800	1.00
28_L	60_L	0.799	1.00
90_R	306_P	0.796	1.00
432_L	457_R	0.794	1.00
435_A	438_L	0.794	1.00
152_V	253_M	0.792	1.00
165_F	169_A	0.792	1.00
333_Q	336_A	0.791	1.00
441_S	445_I	0.791	1.00
471_I	503_I	0.790	1.00
198_E	202_N	0.789	1.00
121_A	292_A	0.789	1.00
399_F	470_I	0.788	1.00
63_A	67_G	0.787	1.00
316_A	394_D	0.787	1.00
212_N	215_I	0.785	1.00
178_L	225_I	0.784	1.00
355_I	521_E	0.782	1.00
485_R	489_Y	0.782	1.00
141_Y	144_M	0.779	1.00
397_K	466_E	0.778	1.00
195_G	198_E	0.777	1.00
144_M	147_G	0.773	1.00
323_L	470_I	0.771	1.00
529_E	536_D	0.771	1.00
314_P	385_K	0.769	1.00
489_Y	512_Y	0.767	1.00
106_S	110_G	0.767	1.00
375_P	379_E	0.765	1.00
405_D	455_K	0.764	1.00
331_A	336_A	0.764	1.00
146_S	150_L	0.764	1.00
309_A	374_Q	0.764	1.00
51_L	55_L	0.761	1.00
358_N	475_E	0.760	1.00
28_L	57_L	0.758	1.00
107_L	302_F	0.758	1.00
155_I	158_A	0.757	1.00
299_L	303_A	0.756	1.00
121_A	289_L	0.756	1.00
314_P	317_F	0.755	1.00
27_A	31_G	0.754	1.00
224_H	227_R	0.754	1.00
321_Q	502_T	0.752	1.00
148_K	151_L	0.752	1.00
14_P	78_H	0.747	1.00
34_A	37_N	0.746	1.00
452_K	479_D	0.742	1.00
132_I	136_I	0.741	1.00
52_P	55_L	0.740	1.00
91_I	99_I	0.737	1.00
440_L	450_L	0.737	1.00
140_A	143_W	0.736	1.00
66_L	70_L	0.733	1.00
220_E	223_H	0.733	1.00
117_N	291_T	0.732	1.00
146_S	260_A	0.732	1.00
131_G	281_S	0.730	1.00
457_R	484_F	0.729	1.00
22_S	130_Q	0.729	1.00
143_W	154_A	0.725	1.00
349_G	500_G	0.725	1.00
53_E	56_G	0.724	1.00
336_A	340_G	0.723	1.00
35_F	57_L	0.723	1.00
421_N	466_E	0.721	1.00
433_K	436_H	0.719	1.00
318_P	469_D	0.718	1.00
340_G	524_N	0.718	1.00
145_L	267_T	0.717	1.00
181_T	217_D	0.715	1.00
60_L	64_V	0.715	1.00
20_A	24_A	0.714	1.00
137_G	140_A	0.714	1.00
50_V	53_E	0.712	1.00
477_A	485_R	0.711	1.00
30_I	33_I	0.710	1.00
138_S	274_F	0.710	1.00
35_F	53_E	0.708	1.00
40_L	266_A	0.708	1.00
223_H	227_R	0.707	1.00
80_V	119_T	0.706	1.00
421_N	467_E	0.706	1.00
46_T	50_V	0.706	1.00
177_T	180_E	0.704	1.00
229_D	233_L	0.704	1.00
185_L	221_Y	0.704	1.00
95_H	309_A	0.702	1.00
352_L	530_L	0.701	1.00
410_D	449_K	0.701	1.00
395_Y	399_F	0.701	1.00
162_W	165_F	0.699	1.00
86_E	89_K	0.698	1.00
381_L	386_P	0.697	1.00
488_F	491_V	0.697	1.00
241_I	245_G	0.695	1.00
128_L	132_I	0.695	1.00
110_G	114_D	0.692	1.00
534_E	537_A	0.692	1.00
518_R	532_G	0.692	1.00
421_N	465_A	0.691	1.00
367_M	373_Y	0.691	1.00
150_L	268_Y	0.689	1.00
146_S	149_M	0.688	1.00
428_W	461_L	0.687	1.00
24_A	60_L	0.687	1.00
368_L	373_Y	0.685	1.00
179_R	182_E	0.685	1.00
422_P	429_L	0.685	1.00
94_T	307_F	0.683	1.00
26_A	133_I	0.682	1.00
339_V	522_M	0.680	1.00
297_N	301_K	0.679	1.00
9_R	13_W	0.679	1.00
38_Q	50_V	0.679	1.00
14_P	71_A	0.679	1.00
86_E	303_A	0.678	1.00
138_S	275_L	0.676	1.00
382_L	387_V	0.675	1.00
11_Y	14_P	0.674	1.00
42_E	46_T	0.674	1.00
315_Q	394_D	0.673	1.00
485_R	512_Y	0.673	1.00
349_G	502_T	0.673	1.00
103_G	187_T	0.673	1.00
417_G	444_R	0.671	1.00
169_A	173_K	0.671	1.00
426_E	438_L	0.669	1.00
366_A	504_F	0.667	1.00
513_F	516_A	0.665	1.00
472_L	504_F	0.664	1.00
346_I	350_E	0.664	1.00
325_L	342_I	0.663	1.00
434_M	444_R	0.660	1.00
460_L	464_L	0.658	1.00
87_F	303_A	0.658	1.00
130_Q	134_L	0.657	1.00
460_L	488_F	0.655	1.00
24_A	28_L	0.655	1.00
174_H	177_T	0.655	1.00
149_M	257_L	0.654	1.00
315_Q	391_Q	0.654	1.00
529_E	537_A	0.653	1.00
245_G	249_L	0.651	1.00
292_A	295_A	0.651	1.00
17_S	71_A	0.650	1.00
351_L	515_H	0.649	1.00
430_A	436_H	0.649	1.00
118_I	296_F	0.648	1.00
431_Q	491_V	0.648	1.00
412_L	445_I	0.645	1.00
83_L	115_V	0.645	1.00
78_H	81_Y	0.644	1.00
96_V	100_E	0.643	1.00
34_A	145_L	0.642	1.00
521_E	529_E	0.641	1.00
80_V	84_R	0.640	1.00
418_K	465_A	0.637	1.00
320_W	502_T	0.635	1.00
332_Y	364_T	0.635	1.00
277_T	281_S	0.634	1.00
418_K	424_L	0.634	1.00
310_E	313_R	0.634	1.00
90_R	305_A	0.634	1.00
13_W	16_I	0.632	1.00
109_A	186_Y	0.632	1.00
354_L	504_F	0.630	1.00
120_I	288_T	0.630	1.00
514_I	533_E	0.629	1.00
59_L	63_A	0.629	1.00
482_P	485_R	0.629	1.00
518_R	535_R	0.628	1.00
114_D	179_R	0.628	1.00
87_F	115_V	0.628	1.00
422_P	444_R	0.628	1.00
319_N	398_L	0.626	1.00
330_F	338_S	0.625	1.00
427_K	495_L	0.625	1.00
429_L	432_L	0.624	1.00
413_L	438_L	0.623	1.00
101_Q	333_Q	0.622	1.00
260_A	264_V	0.622	1.00
198_E	201_L	0.620	1.00
183_D	298_K	0.620	1.00
331_A	377_S	0.619	1.00
106_S	298_K	0.619	1.00
530_L	535_R	0.618	1.00
98_R	107_L	0.618	1.00
251_F	254_A	0.616	1.00
131_G	135_T	0.616	1.00
314_P	318_P	0.616	1.00
485_R	511_H	0.616	1.00
227_R	231_F	0.616	1.00
328_V	378_G	0.615	1.00
45_D	48_L	0.615	1.00
48_L	51_L	0.615	1.00
344_L	527_L	0.615	1.00
496_M	501_K	0.614	1.00
342_I	522_M	0.613	1.00
221_Y	225_I	0.611	1.00
223_H	226_I	0.610	1.00
25_S	65_T	0.609	1.00
81_Y	218_A	0.608	1.00
457_R	480_Q	0.608	1.00
153_T	272_L	0.607	1.00
295_A	298_K	0.607	1.00
519_L	532_G	0.606	1.00
440_L	444_R	0.606	1.00
366_A	401_A	0.605	1.00
166_V	169_A	0.605	1.00
83_L	118_I	0.603	1.00
418_K	429_L	0.601	1.00
138_S	271_T	0.600	1.00
433_K	488_F	0.600	1.00
328_V	343_N	0.599	1.00
425_V	429_L	0.599	1.00
537_A	540_R	0.599	1.00
358_N	507_S	0.597	1.00
383_D	469_D	0.597	1.00
334_D	376_Q	0.595	1.00
73_T	123_V	0.595	1.00
491_V	494_P	0.595	1.00
109_A	183_D	0.594	1.00
400_S	466_E	0.594	1.00
470_I	502_T	0.593	1.00
513_F	533_E	0.593	1.00
480_Q	484_F	0.593	1.00
22_S	68_S	0.592	1.00
416_E	458_V	0.592	1.00
11_Y	79_F	0.591	1.00
451_S	454_Q	0.590	1.00
392_P	395_Y	0.590	1.00
16_I	19_M	0.589	1.00
158_A	162_W	0.588	1.00
240_N	280_L	0.588	1.00
336_A	524_N	0.587	1.00
31_G	57_L	0.587	1.00
34_A	267_T	0.587	1.00
260_A	265_A	0.586	1.00
328_V	380_I	0.586	1.00
432_L	464_L	0.585	1.00
321_Q	469_D	0.585	1.00
179_R	294_V	0.585	1.00
244_L	248_G	0.584	1.00
489_Y	505_A	0.584	1.00
29_G	33_I	0.583	1.00
163_G	242_M	0.583	1.00
367_M	401_A	0.582	1.00
95_H	98_R	0.579	1.00
347_K	352_L	0.579	1.00
226_I	229_D	0.579	1.00
127_E	281_S	0.578	1.00
346_I	351_L	0.575	1.00
248_G	252_W	0.575	1.00
88_I	92_L	0.574	1.00
73_T	77_H	0.574	1.00
175_M	228_A	0.574	1.00
358_N	480_Q	0.574	1.00
188_D	192_V	0.573	1.00
64_V	67_G	0.573	1.00
342_I	520_L	0.573	1.00
177_T	220_E	0.572	1.00
109_A	182_E	0.572	1.00
402_V	473_L	0.571	1.00
524_N	528_S	0.570	1.00
104_S	108_L	0.570	1.00
453_G	481_D	0.569	1.00
416_E	462_L	0.569	1.00
337_F	341_P	0.569	1.00
131_G	134_L	0.567	1.00
335_N	338_S	0.567	1.00
432_L	460_L	0.566	1.00
249_L	253_M	0.566	1.00
246_A	249_L	0.565	1.00
148_K	253_M	0.564	1.00
62_M	66_L	0.564	1.00
77_H	80_V	0.563	1.00
116_R	119_T	0.563	1.00
334_D	337_F	0.563	1.00
218_A	222_R	0.563	1.00
224_H	228_A	0.562	1.00
123_V	127_E	0.561	1.00
180_E	184_K	0.561	1.00
26_A	29_G	0.560	1.00
53_E	57_L	0.560	1.00
481_D	484_F	0.559	1.00
105_A	187_T	0.559	1.00
447_N	455_K	0.558	1.00
402_V	476_W	0.557	1.00
430_A	444_R	0.557	1.00
403_F	406_V	0.556	1.00
120_I	123_V	0.556	1.00
167_L	235_A	0.556	1.00
312_P	394_D	0.555	1.00
22_S	26_A	0.555	1.00
19_M	22_S	0.553	1.00
26_A	30_I	0.552	1.00
319_N	348_R	0.550	1.00
355_I	513_F	0.549	1.00
340_G	343_N	0.547	1.00
99_I	102_L	0.547	1.00
382_L	390_E	0.547	1.00
438_L	441_S	0.547	1.00
14_P	18_V	0.547	1.00
490_Q	515_H	0.546	1.00
437_K	443_G	0.546	1.00
464_L	495_L	0.546	1.00
10_Q	13_W	0.546	1.00
312_P	391_Q	0.544	1.00
491_V	495_L	0.544	1.00
109_A	113_S	0.543	1.00
55_L	59_L	0.543	1.00
510_D	533_E	0.543	1.00
233_L	237_N	0.542	1.00
181_T	221_Y	0.542	1.00
385_K	394_D	0.541	1.00
92_L	95_H	0.541	1.00
96_V	372_L	0.541	1.00
470_I	504_F	0.538	1.00
70_L	74_T	0.537	1.00
139_A	143_W	0.537	1.00
234_S	238_W	0.536	1.00
476_W	507_S	0.535	1.00
252_W	255_N	0.535	1.00
35_F	38_Q	0.535	1.00
115_V	299_L	0.534	1.00
354_L	522_M	0.534	1.00
135_T	139_A	0.532	1.00
464_L	491_V	0.532	1.00
25_S	64_V	0.531	1.00
309_A	371_G	0.531	1.00
347_K	502_T	0.531	1.00
484_F	488_F	0.530	1.00
174_H	228_A	0.530	1.00
477_A	480_Q	0.530	1.00
521_E	528_S	0.529	1.00
118_I	299_L	0.529	1.00
318_P	321_Q	0.529	1.00
482_P	511_H	0.528	1.00
507_S	511_H	0.528	1.00
490_Q	493_L	0.528	1.00
364_T	373_Y	0.527	1.00
528_S	540_R	0.527	1.00
417_G	420_A	0.526	1.00
80_V	115_V	0.526	1.00
489_Y	515_H	0.525	1.00
159_I	163_G	0.525	1.00
510_D	513_F	0.524	1.00
182_E	186_Y	0.524	1.00
147_G	150_L	0.524	1.00
154_A	158_A	0.524	1.00
144_M	148_K	0.524	1.00
375_P	386_P	0.523	1.00
346_I	520_L	0.522	1.00
439_E	443_G	0.522	1.00
67_G	71_A	0.521	1.00
354_L	506_I	0.521	1.00
188_D	208_Y	0.520	1.00
308_K	396_R	0.517	1.00
363_S	366_A	0.517	1.00
329_T	339_V	0.516	1.00
355_I	510_D	0.516	1.00
457_R	479_D	0.515	1.00
530_L	539_S	0.515	1.00
484_F	487_E	0.513	1.00
110_G	298_K	0.513	1.00
199_L	205_R	0.513	1.00
97_E	333_Q	0.513	1.00
111_L	115_V	0.513	1.00
190_Q	194_E	0.513	1.00
505_A	513_F	0.513	1.00
404_T	452_K	0.512	1.00
319_N	382_L	0.512	1.00
521_E	531_T	0.512	1.00
345_T	530_L	0.512	1.00
161_I	164_G	0.512	1.00
58_L	62_M	0.512	1.00
324_E	379_E	0.512	1.00
512_Y	516_A	0.511	1.00
251_F	255_N	0.510	1.00
69_Q	73_T	0.509	1.00
473_L	476_W	0.509	1.00
30_I	141_Y	0.509	1.00
496_M	500_G	0.509	1.00
113_S	116_R	0.509	1.00
50_V	54_F	0.509	1.00
476_W	505_A	0.508	1.00
159_I	162_W	0.508	1.00
28_L	32_L	0.507	1.00
31_G	34_A	0.507	1.00
195_G	409_F	0.507	1.00
142_L	153_T	0.507	1.00
223_H	230_T	0.507	1.00
319_N	322_T	0.506	1.00
70_L	73_T	0.505	1.00
338_S	342_I	0.505	1.00
437_K	444_R	0.505	1.00
10_Q	86_E	0.504	1.00
414_G	465_A	0.503	1.00
318_P	385_K	0.503	1.00
228_A	232_H	0.502	1.00
391_Q	395_Y	0.502	1.00
536_D	541_D	0.500	1.00
460_L	480_Q	0.500	1.00
37_N	263_N	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4ry2A	2	0.9726	100	0.085	Contact Map
4a82A	2	0.9927	100	0.115	Contact Map
4q4hB	1	0.9927	100	0.146	Contact Map
3b5xA	2	0.9927	100	0.149	Contact Map
3b60A	2	0.9927	100	0.152	Contact Map
4f4cA	1	0.9799	100	0.153	Contact Map
3zdqA	2	0.9781	100	0.159	Contact Map
4q4hA	1	0.9927	100	0.161	Contact Map
4q9hA	1	0.9927	100	0.168	Contact Map
4mrsA	2	0.9927	100	0.171	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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