MQO - ECOLI - GREMLIN Contacts

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MQO - Malate:quinone oxidoreductase

UniProt:	P33940	Sequences: MKKVTAMLFSMAVGLNAVSMAAKAKASEEQETDVLLIGGGIMSATLGTYLRELEPEWSMTMVERLEGVAQESSNGWNNAGTGHSALMELNYTPQNADGSISIEKAVAINEAFQISRQFWAHQVERGVLRTPRSFINTVPHMSFVWGEDNVNFLRARYAALQQSSLFRGMRYSEDHAQIKEWAPLVMEGRDPQQKVAATRTEIGTDVNYGEITRQLIASLQKKSNFSLQLSSEVRALKRNDDNTWTVTVADLKNGTAQNIRAKFVFIGAGGAALKLLQESGIPEAKDYAGFPVGGQFLVSENPDVVNHHLAKVYGKASVGAPPMSVPHIDTRVLDGKRVVLFGPFATFSTKFLKNGSLWDLMSSTTTSNVMPMMHVGLDNFDLVKYLVSQVMLSEEDRFEALKEYYPQAKKEDWRLWQAGQRVQIIKRDAEKGGVLRLGTEVVSDQQGTIAALLGASPGASTAAPIMLNLLEKVFGDRVSSPQWQATLKAIVPSYGRKLNGDVAATERELQYTSEVLGLNYDKPQAADSTPKPQLKPQPVQKEVADIAL	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG12069
Length:	548 (480)
Sequences:	1153 (656)
Seq/√Len:	30.0

ECOLI - MQO

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
64_R	232_E	4.486	1.00
61_M	216_I	4.323	1.00
187_E	307_H	4.260	1.00
177_Q	180_E	4.230	1.00
68_V	229_L	4.184	1.00
496_R	501_D	3.959	1.00
124_E	511_Y	3.934	1.00
178_I	182_A	3.863	1.00
151_N	155_A	3.831	1.00
121_H	490_I	3.438	1.00
373_M	377_L	3.388	1.00
398_F	410_K	3.324	1.00
35_L	246_V	3.264	1.00
37_I	266_I	3.128	1.00
293_G	346_T	3.035	1.00
32_T	60_T	3.016	1.00
182_A	185_V	3.014	1.00
250_D	253_N	2.816	1.00
170_R	177_Q	2.765	1.00
478_V	494_Y	2.741	1.00
296_F	416_W	2.701	1.00
39_G	68_V	2.694	1.00
62_V	259_I	2.670	1.00
188_G	407_Q	2.666	1.00
317_S	403_E	2.495	0.99
95_N	101_S	2.482	0.99
306_N	337_R	2.478	0.99
95_N	99_S	2.453	0.99
236_L	279_S	2.430	0.99
508_E	511_Y	2.399	0.99
102_I	163_S	2.397	0.99
371_P	374_H	2.387	0.99
86_L	200_T	2.370	0.99
113_Q	509_L	2.365	0.99
468_N	471_E	2.351	0.99
300_E	414_R	2.332	0.99
163_S	499_N	2.321	0.99
54_E	57_W	2.303	0.99
266_I	451_A	2.302	0.99
147_E	194_K	2.299	0.99
235_A	278_E	2.184	0.98
371_P	427_R	2.169	0.98
239_N	243_T	2.157	0.98
279_S	449_I	2.102	0.98
143_F	185_V	2.096	0.98
295_Q	415_L	2.094	0.98
496_R	504_A	2.075	0.98
395_E	410_K	2.054	0.97
263_F	450_A	2.043	0.97
44_A	216_I	2.033	0.97
132_R	136_N	2.023	0.97
100_I	155_A	2.018	0.97
164_S	502_V	1.987	0.97
157_Y	161_Q	1.959	0.97
300_E	336_K	1.958	0.97
39_G	61_M	1.944	0.96
33_D	262_K	1.933	0.96
75_G	333_L	1.925	0.96
301_N	412_D	1.916	0.96
238_R	448_T	1.901	0.96
284_A	451_A	1.899	0.96
468_N	472_K	1.891	0.96
101_S	104_K	1.889	0.96
62_V	248_V	1.888	0.96
505_T	509_L	1.871	0.96
389_Q	392_L	1.869	0.96
149_N	315_K	1.869	0.96
61_M	225_F	1.866	0.96
350_K	357_L	1.853	0.95
506_E	510_Q	1.850	0.95
39_G	229_L	1.846	0.95
231_S	248_V	1.844	0.95
441_V	469_L	1.824	0.95
383_V	387_V	1.786	0.94
394_E	398_F	1.785	0.94
398_F	402_K	1.782	0.94
167_R	506_E	1.764	0.94
172_S	177_Q	1.726	0.93
289_G	422_V	1.722	0.93
176_A	179_K	1.719	0.93
300_E	338_V	1.719	0.93
484_Q	488_K	1.708	0.93
36_L	43_S	1.689	0.92
151_N	154_R	1.683	0.92
141_M	182_A	1.678	0.92
35_L	259_I	1.676	0.92
436_R	465_I	1.673	0.92
384_K	388_S	1.671	0.92
164_S	505_T	1.670	0.92
121_H	125_R	1.670	0.92
216_I	227_L	1.668	0.92
51_R	224_N	1.664	0.92
444_D	448_T	1.662	0.92
393_S	396_D	1.657	0.92
243_T	262_K	1.647	0.91
469_L	478_V	1.635	0.91
302_P	305_V	1.630	0.91
52_E	125_R	1.623	0.91
154_R	173_E	1.582	0.90
57_W	296_F	1.563	0.89
389_Q	400_A	1.556	0.89
380_F	383_V	1.548	0.89
141_M	177_Q	1.544	0.89
62_V	231_S	1.543	0.88
94_Q	100_I	1.537	0.88
179_K	187_E	1.517	0.88
49_Y	490_I	1.507	0.87
504_A	508_E	1.490	0.87
219_L	225_F	1.488	0.87
113_Q	116_R	1.485	0.86
133_S	214_Q	1.484	0.86
298_V	344_F	1.476	0.86
274_K	362_S	1.435	0.84
35_L	62_V	1.428	0.84
309_L	337_R	1.427	0.84
35_L	261_A	1.413	0.84
86_L	109_N	1.407	0.83
373_M	376_G	1.400	0.83
37_I	47_G	1.396	0.83
31_E	262_K	1.395	0.83
178_I	185_V	1.392	0.83
497_K	500_G	1.391	0.83
129_R	214_Q	1.390	0.83
392_L	400_A	1.382	0.82
477_R	482_Q	1.377	0.82
86_L	113_Q	1.377	0.82
108_I	116_R	1.377	0.82
145_W	193_Q	1.368	0.81
486_T	489_A	1.360	0.81
94_Q	155_A	1.360	0.81
123_V	131_P	1.356	0.81
67_G	213_R	1.356	0.81
31_E	260_R	1.355	0.81
66_E	230_S	1.351	0.81
279_S	284_A	1.346	0.80
32_T	259_I	1.342	0.80
36_L	47_G	1.339	0.80
48_T	51_R	1.337	0.80
502_V	506_E	1.335	0.80
68_V	428_D	1.335	0.80
187_E	191_P	1.332	0.80
479_S	484_Q	1.327	0.79
32_T	35_L	1.326	0.79
115_S	119_W	1.322	0.79
95_N	103_E	1.309	0.79
41_I	348_S	1.306	0.78
378_D	431_K	1.303	0.78
361_M	364_T	1.288	0.77
376_G	380_F	1.287	0.77
60_T	226_S	1.286	0.77
316_A	324_S	1.283	0.77
471_E	484_Q	1.282	0.77
364_T	369_V	1.282	0.77
185_V	404_Y	1.272	0.76
187_E	407_Q	1.267	0.76
41_I	44_A	1.264	0.76
52_E	486_T	1.259	0.76
230_S	251_L	1.250	0.75
130_T	133_S	1.235	0.74
505_T	508_E	1.226	0.74
84_S	116_R	1.225	0.74
94_Q	99_S	1.219	0.73
500_G	505_T	1.219	0.73
234_R	242_N	1.218	0.73
232_E	251_L	1.211	0.73
32_T	128_L	1.211	0.73
288_A	383_V	1.208	0.73
299_S	304_V	1.206	0.72
392_L	397_R	1.203	0.72
48_T	215_L	1.201	0.72
305_V	338_V	1.201	0.72
230_S	252_K	1.199	0.72
191_P	194_K	1.197	0.72
243_T	260_R	1.188	0.71
73_S	215_L	1.181	0.71
444_D	450_A	1.181	0.71
67_G	70_Q	1.180	0.71
302_P	336_K	1.176	0.71
503_A	506_E	1.171	0.70
239_N	260_R	1.164	0.70
60_T	259_I	1.163	0.70
399_E	402_K	1.156	0.69
207_N	334_D	1.154	0.69
147_E	151_N	1.147	0.69
74_N	296_F	1.145	0.68
388_S	391_M	1.139	0.68
62_V	228_Q	1.136	0.68
75_G	332_V	1.133	0.68
301_N	304_V	1.127	0.67
263_F	473_V	1.123	0.67
375_V	380_F	1.115	0.66
231_S	257_Q	1.113	0.66
176_A	180_E	1.110	0.66
485_A	488_K	1.109	0.66
106_V	499_N	1.106	0.66
253_N	256_A	1.101	0.65
428_D	434_V	1.101	0.65
174_D	177_Q	1.098	0.65
164_S	499_N	1.088	0.64
333_L	338_V	1.086	0.64
168_G	200_T	1.086	0.64
178_I	186_M	1.080	0.64
86_L	509_L	1.077	0.64
499_N	502_V	1.070	0.63
47_G	61_M	1.066	0.63
332_V	337_R	1.055	0.62
68_V	216_I	1.052	0.62
173_E	430_E	1.051	0.62
400_A	403_E	1.050	0.62
92_T	152_F	1.049	0.62
491_V	494_Y	1.043	0.61
90_N	322_P	1.040	0.61
85_A	337_R	1.039	0.61
74_N	391_M	1.029	0.60
301_N	305_V	1.028	0.60
84_S	109_N	1.020	0.59
470_L	478_V	1.017	0.59
83_H	457_P	1.014	0.59
293_G	417_Q	1.012	0.59
96_A	99_S	1.012	0.59
47_G	219_L	1.011	0.59
155_A	159_A	1.011	0.59
239_N	245_T	1.008	0.58
144_V	149_N	1.005	0.58
150_V	305_V	1.004	0.58
374_H	378_D	1.003	0.58
357_L	361_M	1.002	0.58
426_K	440_E	1.002	0.58
186_M	195_V	1.000	0.58
503_A	507_R	0.999	0.58
141_M	178_I	0.995	0.57
286_D	437_L	0.993	0.57
94_Q	315_K	0.990	0.57
75_G	138_V	0.988	0.57
250_D	257_Q	0.985	0.57
188_G	394_E	0.985	0.57
402_K	410_K	0.985	0.57
136_N	178_I	0.982	0.56
110_E	165_L	0.981	0.56
58_S	225_F	0.977	0.56
52_E	127_V	0.976	0.56
482_Q	503_A	0.973	0.56
394_E	410_K	0.967	0.55
83_H	91_Y	0.964	0.55
31_E	243_T	0.963	0.55
493_S	508_E	0.959	0.55
106_V	164_S	0.959	0.55
502_V	505_T	0.949	0.54
344_F	392_L	0.948	0.54
143_F	195_V	0.948	0.54
84_S	113_Q	0.948	0.54
286_D	427_R	0.948	0.54
47_G	59_M	0.946	0.54
450_A	466_M	0.944	0.53
497_K	501_D	0.943	0.53
255_T	258_N	0.937	0.53
487_L	491_V	0.937	0.53
96_A	510_Q	0.936	0.53
304_V	405_Y	0.936	0.53
282_P	445_Q	0.932	0.52
129_R	133_S	0.931	0.52
190_D	193_Q	0.926	0.52
121_H	489_A	0.923	0.52
210_E	217_A	0.922	0.52
75_G	298_V	0.918	0.51
61_M	227_L	0.918	0.51
172_S	198_T	0.917	0.51
381_D	388_S	0.915	0.51
102_I	152_F	0.915	0.51
220_Q	227_L	0.914	0.51
35_L	213_R	0.914	0.51
170_R	201_E	0.912	0.51
68_V	130_T	0.909	0.51
172_S	175_H	0.908	0.51
165_L	447_G	0.905	0.50
397_R	415_L	0.903	0.50
46_L	466_M	0.899	0.50
391_M	396_D	0.897	0.50
70_Q	180_E	0.895	0.50
496_R	509_L	0.892	0.49
85_A	461_T	0.888	0.49
245_T	260_R	0.887	0.49
44_A	215_L	0.886	0.49
172_S	178_I	0.883	0.49
121_H	192_Q	0.883	0.49
266_I	284_A	0.882	0.48
471_E	494_Y	0.879	0.48
136_N	332_V	0.879	0.48
498_L	504_A	0.879	0.48
286_D	436_R	0.875	0.48
488_K	496_R	0.873	0.48
128_L	214_Q	0.870	0.48
58_S	224_N	0.868	0.47
254_G	282_P	0.868	0.47
307_H	407_Q	0.865	0.47
296_F	299_S	0.863	0.47
130_T	136_N	0.863	0.47
374_H	377_L	0.858	0.47
178_I	197_A	0.856	0.46
240_D	255_T	0.854	0.46
295_Q	417_Q	0.854	0.46
128_L	505_T	0.851	0.46
60_T	228_Q	0.851	0.46
431_K	434_V	0.851	0.46
330_T	337_R	0.850	0.46
349_T	390_V	0.847	0.46
173_E	194_K	0.845	0.46
67_G	255_T	0.845	0.46
181_W	440_E	0.844	0.45
182_A	186_M	0.842	0.45
150_V	194_K	0.840	0.45
375_V	383_V	0.834	0.45
507_R	511_Y	0.832	0.45
175_H	179_K	0.829	0.44
188_G	405_Y	0.824	0.44
102_I	499_N	0.823	0.44
102_I	106_V	0.823	0.44
200_T	509_L	0.822	0.44
190_D	229_L	0.821	0.44
131_P	135_I	0.819	0.44
175_H	191_P	0.818	0.43
114_I	464_P	0.816	0.43
101_S	231_S	0.813	0.43
148_D	400_A	0.812	0.43
99_S	173_E	0.811	0.43
37_I	128_L	0.810	0.43
292_V	383_V	0.806	0.43
488_K	491_V	0.806	0.43
34_V	47_G	0.799	0.42
40_G	43_S	0.798	0.42
66_E	70_Q	0.797	0.42
83_H	456_S	0.794	0.42
122_Q	211_I	0.792	0.41
96_A	489_A	0.790	0.41
92_T	100_I	0.788	0.41
39_G	138_V	0.787	0.41
37_I	62_V	0.787	0.41
115_S	135_I	0.785	0.41
343_P	457_P	0.783	0.41
111_A	484_Q	0.782	0.41
95_N	490_I	0.778	0.40
175_H	510_Q	0.776	0.40
117_Q	498_L	0.774	0.40
32_T	74_N	0.772	0.40
111_A	464_P	0.771	0.40
313_Y	327_H	0.770	0.40
304_V	307_H	0.770	0.40
69_A	268_A	0.769	0.40
37_I	40_G	0.769	0.40
148_D	430_E	0.768	0.40
486_T	490_I	0.768	0.40
195_V	496_R	0.766	0.39
300_E	305_V	0.764	0.39
112_F	115_S	0.764	0.39
121_H	486_T	0.763	0.39
290_F	425_I	0.762	0.39
113_Q	379_N	0.761	0.39
500_G	507_R	0.760	0.39
497_K	504_A	0.760	0.39
154_R	262_K	0.758	0.39
504_A	507_R	0.754	0.39
66_E	252_K	0.753	0.38
236_L	256_A	0.751	0.38
261_A	264_V	0.750	0.38
132_R	201_E	0.750	0.38
130_T	496_R	0.750	0.38
86_L	404_Y	0.747	0.38
181_W	198_T	0.747	0.38
217_A	221_K	0.746	0.38
240_D	254_G	0.744	0.38
380_F	467_L	0.742	0.38
344_F	398_F	0.736	0.37
507_R	510_Q	0.735	0.37
154_R	179_K	0.735	0.37
165_L	497_K	0.734	0.37
500_G	504_A	0.733	0.37
70_Q	74_N	0.733	0.37
333_L	340_L	0.733	0.37
176_A	285_K	0.732	0.37
224_N	266_I	0.731	0.37
101_S	489_A	0.730	0.37
35_L	75_G	0.729	0.37
236_L	264_V	0.728	0.37
38_G	43_S	0.726	0.36
54_E	296_F	0.723	0.36
102_I	442_V	0.722	0.36
132_R	238_R	0.721	0.36
192_Q	217_A	0.721	0.36
154_R	158_A	0.719	0.36
87_M	286_D	0.718	0.36
248_V	257_Q	0.718	0.36
120_A	150_V	0.718	0.36
383_V	390_V	0.718	0.36
299_S	333_L	0.715	0.36
261_A	449_I	0.712	0.35
111_A	116_R	0.709	0.35
496_R	507_R	0.708	0.35
234_R	249_A	0.705	0.35
324_S	455_A	0.704	0.35
163_S	502_V	0.704	0.35
102_I	162_Q	0.703	0.35
485_A	507_R	0.702	0.35
65_L	85_A	0.702	0.35
299_S	330_T	0.702	0.35
49_Y	118_F	0.701	0.35
295_Q	392_L	0.701	0.35
96_A	129_R	0.699	0.35
90_N	324_S	0.698	0.34
268_A	297_L	0.698	0.34
488_K	501_D	0.698	0.34
327_H	343_P	0.698	0.34
132_R	506_E	0.697	0.34
346_T	473_V	0.696	0.34
487_L	507_R	0.693	0.34
118_F	304_V	0.693	0.34
241_D	511_Y	0.691	0.34
328_I	469_L	0.691	0.34
428_D	431_K	0.690	0.34
128_L	136_N	0.690	0.34
497_K	502_V	0.690	0.34
357_L	362_S	0.688	0.34
107_A	469_L	0.688	0.34
129_R	163_S	0.687	0.34
357_L	400_A	0.686	0.34
388_S	399_E	0.685	0.34
93_P	296_F	0.684	0.33
76_W	298_V	0.684	0.33
334_D	412_D	0.684	0.33
274_K	363_S	0.683	0.33
164_S	500_G	0.683	0.33
496_R	508_E	0.682	0.33
121_H	337_R	0.679	0.33
124_E	496_R	0.678	0.33
114_I	405_Y	0.678	0.33
479_S	485_A	0.678	0.33
148_D	188_G	0.677	0.33
428_D	432_G	0.676	0.33
82_G	460_S	0.676	0.33
378_D	429_A	0.676	0.33
185_V	312_V	0.675	0.33
178_I	288_A	0.675	0.33
42_M	46_L	0.674	0.33
103_E	255_T	0.672	0.33
409_K	412_D	0.668	0.32
251_L	496_R	0.667	0.32
33_D	38_G	0.667	0.32
75_G	464_P	0.666	0.32
230_S	507_R	0.665	0.32
39_G	417_Q	0.663	0.32
74_N	213_R	0.663	0.32
120_A	129_R	0.662	0.32
503_A	510_Q	0.661	0.32
168_G	202_I	0.661	0.32
108_I	166_F	0.660	0.32
364_T	485_A	0.659	0.32
110_E	497_K	0.658	0.32
398_F	511_Y	0.657	0.32
305_V	337_R	0.655	0.31
81_T	311_K	0.653	0.31
252_K	510_Q	0.653	0.31
110_E	467_L	0.653	0.31
302_P	306_N	0.652	0.31
144_V	153_L	0.649	0.31
379_N	509_L	0.648	0.31
190_D	253_N	0.646	0.31
100_I	162_Q	0.643	0.31
37_I	354_N	0.642	0.31
234_R	354_N	0.642	0.31
160_L	166_F	0.640	0.30
124_E	220_Q	0.640	0.30
172_S	181_W	0.639	0.30
114_I	491_V	0.639	0.30
501_D	504_A	0.637	0.30
173_E	510_Q	0.637	0.30
141_M	195_V	0.637	0.30
400_A	444_D	0.636	0.30
127_V	218_S	0.636	0.30
506_E	509_L	0.635	0.30
488_K	495_G	0.633	0.30
344_F	402_K	0.633	0.30
70_Q	287_Y	0.633	0.30
106_V	497_K	0.633	0.30
75_G	225_F	0.633	0.30
80_G	331_R	0.632	0.30
76_W	273_L	0.632	0.30
94_Q	251_L	0.630	0.30
33_D	40_G	0.629	0.30
51_R	229_L	0.628	0.30
31_E	47_G	0.628	0.30
112_F	119_W	0.625	0.29
195_V	404_Y	0.623	0.29
57_W	164_S	0.623	0.29
271_A	422_V	0.622	0.29
272_A	410_K	0.622	0.29
102_I	108_I	0.621	0.29
108_I	163_S	0.620	0.29
226_S	262_K	0.619	0.29
210_E	334_D	0.618	0.29
316_A	455_A	0.618	0.29
157_Y	410_K	0.617	0.29
74_N	334_D	0.616	0.29
169_M	324_S	0.616	0.29
348_S	420_Q	0.616	0.29
304_V	489_A	0.615	0.29
117_Q	135_I	0.614	0.29
351_F	360_L	0.613	0.29
47_G	314_G	0.611	0.28
333_L	365_T	0.611	0.28
502_V	510_Q	0.610	0.28
107_A	497_K	0.608	0.28
44_A	261_A	0.608	0.28
207_N	301_N	0.608	0.28
192_Q	507_R	0.607	0.28
173_E	499_N	0.606	0.28
58_S	245_T	0.606	0.28
248_V	488_K	0.606	0.28
120_A	305_V	0.605	0.28
96_A	477_R	0.605	0.28
346_T	417_Q	0.604	0.28
280_G	381_D	0.604	0.28
501_D	508_E	0.604	0.28
500_G	506_E	0.604	0.28
495_G	504_A	0.604	0.28
501_D	507_R	0.603	0.28
249_A	254_G	0.602	0.28
85_A	104_K	0.602	0.28
154_R	240_D	0.601	0.28
60_T	257_Q	0.601	0.28
188_G	282_P	0.601	0.28
274_K	361_M	0.600	0.28
84_S	232_E	0.600	0.28
96_A	255_T	0.599	0.28
213_R	227_L	0.599	0.28
279_S	286_D	0.599	0.28
327_H	457_P	0.599	0.28
112_F	117_Q	0.598	0.28
37_I	216_I	0.598	0.28
152_F	201_E	0.596	0.28
32_T	334_D	0.596	0.28
247_T	258_N	0.596	0.28
254_G	258_N	0.595	0.27
297_L	398_F	0.594	0.27
258_N	411_E	0.594	0.27
315_K	361_M	0.594	0.27
295_Q	397_R	0.593	0.27
106_V	469_L	0.593	0.27
130_T	500_G	0.592	0.27
63_E	78_N	0.592	0.27
132_R	485_A	0.592	0.27
266_I	449_I	0.592	0.27
217_A	220_Q	0.592	0.27
369_V	404_Y	0.592	0.27
39_G	445_Q	0.591	0.27
86_L	202_I	0.591	0.27
60_T	469_L	0.589	0.27
317_S	447_G	0.589	0.27
271_A	393_S	0.587	0.27
443_S	450_A	0.587	0.27
50_L	483_W	0.587	0.27
258_N	334_D	0.585	0.27
311_K	329_D	0.584	0.27
429_A	468_N	0.584	0.27
147_E	230_S	0.584	0.27
109_N	200_T	0.583	0.27
68_V	227_L	0.583	0.27
299_S	305_V	0.582	0.27
147_E	162_Q	0.582	0.27
210_E	214_Q	0.582	0.27
147_E	193_Q	0.581	0.27
150_V	171_Y	0.580	0.27
132_R	490_I	0.579	0.26
345_A	423_Q	0.578	0.26
362_S	394_E	0.575	0.26
176_A	489_A	0.574	0.26
395_E	398_F	0.574	0.26
48_T	118_F	0.574	0.26
58_S	259_I	0.574	0.26
132_R	239_N	0.574	0.26
125_R	129_R	0.573	0.26
385_Y	452_L	0.573	0.26
254_G	482_Q	0.573	0.26
58_S	172_S	0.572	0.26
61_M	306_N	0.572	0.26
86_L	349_T	0.572	0.26
87_M	328_I	0.571	0.26
147_E	496_R	0.571	0.26
164_S	417_Q	0.570	0.26
67_G	100_I	0.570	0.26
228_Q	231_S	0.569	0.26
240_D	430_E	0.568	0.26
427_R	434_V	0.566	0.26
447_G	466_M	0.565	0.26
120_A	239_N	0.565	0.26
181_W	197_A	0.562	0.25
427_R	501_D	0.561	0.25
491_V	501_D	0.561	0.25
32_T	404_Y	0.561	0.25
227_L	259_I	0.561	0.25
221_K	500_G	0.560	0.25
288_A	360_L	0.559	0.25
488_K	494_Y	0.559	0.25
154_R	369_V	0.557	0.25
160_L	165_L	0.556	0.25
125_R	489_A	0.554	0.25
188_G	239_N	0.553	0.25
490_I	494_Y	0.553	0.25
155_A	158_A	0.552	0.25
116_R	505_T	0.552	0.25
151_N	303_D	0.551	0.25
75_G	416_W	0.551	0.25
141_M	169_M	0.550	0.25
127_V	214_Q	0.550	0.25
129_R	505_T	0.548	0.25
32_T	226_S	0.548	0.25
100_I	161_Q	0.548	0.25
274_K	422_V	0.547	0.25
250_D	451_A	0.547	0.25
61_M	194_K	0.546	0.24
155_A	171_Y	0.546	0.24
109_N	128_L	0.546	0.24
138_V	332_V	0.545	0.24
224_N	227_L	0.545	0.24
358_W	399_E	0.545	0.24
476_D	496_R	0.545	0.24
128_L	163_S	0.545	0.24
240_D	262_K	0.544	0.24
75_G	375_V	0.543	0.24
497_K	505_T	0.543	0.24
132_R	354_N	0.543	0.24
370_M	374_H	0.543	0.24
79_A	460_S	0.542	0.24
41_I	465_I	0.541	0.24
384_K	491_V	0.540	0.24
284_A	357_L	0.540	0.24
303_D	402_K	0.539	0.24
84_S	168_G	0.539	0.24
35_L	60_T	0.539	0.24
320_A	324_S	0.539	0.24
392_L	396_D	0.539	0.24
35_L	349_T	0.537	0.24
143_F	442_V	0.535	0.24
414_R	490_I	0.535	0.24
216_I	336_K	0.534	0.24
113_Q	202_I	0.534	0.24
429_A	432_G	0.534	0.24
83_H	183_P	0.533	0.24
157_Y	163_S	0.533	0.24
308_H	352_L	0.533	0.24
445_Q	482_Q	0.532	0.24
75_G	145_W	0.532	0.24
81_T	329_D	0.532	0.24
407_Q	506_E	0.531	0.24
380_F	449_I	0.531	0.24
253_N	279_S	0.530	0.24
67_G	332_V	0.530	0.24
130_T	370_M	0.529	0.23
190_D	510_Q	0.529	0.23
118_F	463_A	0.528	0.23
75_G	374_H	0.528	0.23
35_L	59_M	0.528	0.23
178_I	465_I	0.526	0.23
145_W	149_N	0.526	0.23
207_N	300_E	0.526	0.23
263_F	346_T	0.526	0.23
286_D	371_P	0.525	0.23
64_R	509_L	0.524	0.23
376_G	383_V	0.524	0.23
61_M	309_L	0.521	0.23
255_T	479_S	0.521	0.23
125_R	176_A	0.521	0.23
237_K	247_T	0.521	0.23
39_G	231_S	0.521	0.23
132_R	429_A	0.520	0.23
51_R	488_K	0.520	0.23
250_D	255_T	0.520	0.23
140_H	460_S	0.519	0.23
212_T	410_K	0.518	0.23
217_A	407_Q	0.517	0.23
138_V	436_R	0.517	0.23
118_F	280_G	0.516	0.23
128_L	496_R	0.515	0.23
79_A	343_P	0.515	0.23
145_W	403_E	0.515	0.23
400_A	485_A	0.515	0.23
180_E	303_D	0.514	0.23
130_T	157_Y	0.514	0.23
145_W	505_T	0.514	0.23
239_N	402_K	0.513	0.23
70_Q	511_Y	0.513	0.23
298_V	333_L	0.512	0.23
173_E	507_R	0.511	0.22
122_Q	127_V	0.511	0.22
126_G	243_T	0.510	0.22
339_V	433_G	0.509	0.22
81_T	90_N	0.508	0.22
477_R	483_W	0.508	0.22
221_K	477_R	0.508	0.22
195_V	403_E	0.508	0.22
216_I	225_F	0.507	0.22
100_I	260_R	0.507	0.22
202_I	215_L	0.506	0.22
318_V	324_S	0.505	0.22
48_T	231_S	0.505	0.22
220_Q	226_S	0.505	0.22
274_K	364_T	0.504	0.22
125_R	192_Q	0.504	0.22
342_G	456_S	0.504	0.22
188_G	292_V	0.504	0.22
136_N	214_Q	0.504	0.22
34_V	263_F	0.504	0.22
306_N	381_D	0.503	0.22
366_T	381_D	0.503	0.22
96_A	502_V	0.503	0.22
97_D	253_N	0.503	0.22
52_E	218_S	0.503	0.22
83_H	342_G	0.501	0.22
224_N	230_S	0.501	0.22
102_I	175_H	0.501	0.22
365_T	472_K	0.500	0.22
84_S	160_L	0.500	0.22

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3dmeA	2	0.6588	100	0.712	Contact Map
3da1A	1	0.7354	100	0.715	Contact Map
2rghA	2	0.8066	100	0.718	Contact Map
2qcuA	2	0.7719	100	0.725	Contact Map
4x9mA	1	0.6916	100	0.726	Contact Map
4h1bA	1	0.6898	100	0.729	Contact Map
3axbA	2	0.708	100	0.742	Contact Map
1y56B	1	0.6807	100	0.743	Contact Map
3pvcA	1	0.7281	100	0.744	Contact Map
1ryiA	4	0.6624	100	0.745	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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