CCMF - ECOLI - GREMLIN Contacts

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CCMF - Cytochrome c-type biogenesis protein CcmF

UniProt:	P33927	Sequences: MMPEIGNGLLCLALGIALLLSVYPLWGVARGDARMMASSRLFAWLLFMSVAGAFLVLVNAFVVNDFTVTYVASNSNTQLPVWYRVAATWGAHEGSLLLWVLLMSGWTFAVAIFSQRIPLDIVARVLAIMGMVSVGFLLFILFTSNPFSRTLPNFPIEGRDLNPLLQDPGLIFHPPLLYMGYVGFSVAFAFAIASLLSGRLDSTYARFTRPWTLAAWIFLTLGIVLGSAWAYYELGWGGWWFWDPVENASFMPWLVGTALMHSLAVTEQRASFKAWTLLLAISAFSLCLLGTFLVRSGVLVSVHAFASDPARGMFILAFMVLVIGGSLLLFAARGHKVRSRVNNALWSRESLLLANNVLLVAAMLVVLLGTLLPLVHKQLGLGSISIGEPFFNTMFTWLMVPFALLLGVGPLVRWGRDRPRKIRNLLIIAFISTLVLSLLLPWLFESKVVAMTVLGLAMACWIAVLAIAEAALRISRGTKTTFSYWGMVAAHLGLAVTIVGIAFSQNYSVERDVRMKSGDSVDIHEYRFTFRDVKEVTGPNWRGGVATIGVTRDGKPETVLYAEKRYYNTAGSMMTEAAIDGGITRDLYAALGEELENGAWAVRLYYKPFVRWIWAGGLMMALGGLLCLFDPRYRKRVSPQKTAPEAV	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG12054
Length:	647 (631)
Sequences:	1446 (953)
Seq/√Len:	38.0

ECOLI - CCMF NRFE

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
184_F	256_G	6.866	1.00
64_N	84_R	5.995	1.00
58_V	88_T	5.314	1.00
62_V	85_V	5.011	1.00
531_R	549_G	4.924	1.00
81_V	85_V	4.579	1.00
77_T	157_E	4.547	1.00
51_A	101_L	4.370	1.00
224_V	617_G	4.272	1.00
70_Y	91_A	4.198	1.00
529_T	551_T	4.089	1.00
515_M	519_D	4.052	1.00
16_I	45_L	3.936	1.00
233_E	576_E	3.912	1.00
138_L	142_F	3.847	1.00
545_V	563_E	3.767	1.00
62_V	81_V	3.662	1.00
255_V	283_A	3.613	1.00
59_N	63_V	3.487	1.00
184_F	283_A	3.399	1.00
16_I	49_S	3.342	1.00
328_L	332_A	3.302	1.00
21_S	131_M	3.274	1.00
503_F	609_F	3.242	1.00
135_G	318_F	3.161	1.00
351_L	412_V	3.092	1.00
581_G	611_R	3.059	1.00
482_F	629_F	3.052	1.00
562_A	578_A	3.007	1.00
403_A	498_I	2.921	1.00
83_Y	168_P	2.878	1.00
496_V	619_M	2.854	1.00
20_L	46_L	2.833	1.00
560_L	578_A	2.818	1.00
463_A	499_V	2.758	1.00
47_F	105_G	2.747	1.00
548_I	602_V	2.743	1.00
50_V	104_S	2.734	1.00
3_P	60_A	2.702	1.00
54_F	88_T	2.675	1.00
250_F	399_M	2.659	1.00
221_L	621_A	2.655	1.00
223_I	249_S	2.595	1.00
255_V	363_M	2.558	1.00
45_L	49_S	2.478	1.00
522_D	525_E	2.462	1.00
25_L	127_A	2.438	1.00
548_I	589_A	2.424	1.00
54_F	58_V	2.424	1.00
79_L	87_A	2.414	1.00
74_N	91_A	2.392	1.00
517_S	530_F	2.352	1.00
522_D	527_R	2.326	1.00
8_G	12_L	2.299	1.00
536_V	545_V	2.299	1.00
524_H	606_Y	2.285	1.00
547_T	559_V	2.269	0.99
72_A	150_T	2.252	0.99
500_G	616_G	2.208	0.99
5_I	52_G	2.202	0.99
543_G	563_E	2.190	0.99
20_L	130_G	2.187	0.99
377_K	383_S	2.168	0.99
318_F	322_V	2.164	0.99
54_F	101_L	2.158	0.99
69_T	73_S	2.145	0.99
515_M	520_S	2.145	0.99
528_F	548_I	2.140	0.99
437_S	457_A	2.115	0.99
580_D	585_R	2.109	0.99
47_F	108_F	2.096	0.99
60_A	63_V	2.090	0.99
551_T	554_G	2.086	0.99
50_V	137_L	2.023	0.99
262_S	356_N	1.972	0.99
86_A	170_L	1.966	0.99
407_G	465_L	1.964	0.98
504_S	508_S	1.960	0.98
61_F	70_Y	1.948	0.98
520_S	529_T	1.940	0.98
497_T	501_I	1.939	0.98
129_M	185_S	1.922	0.98
520_S	527_R	1.918	0.98
460_C	464_V	1.903	0.98
20_L	107_T	1.893	0.98
168_P	172_F	1.875	0.98
463_A	492_L	1.870	0.98
66_F	77_T	1.853	0.98
547_T	561_Y	1.843	0.98
13_A	137_L	1.830	0.98
256_G	283_A	1.813	0.97
486_G	623_G	1.809	0.97
44_W	111_A	1.808	0.97
433_T	437_S	1.807	0.97
58_V	62_V	1.793	0.97
176_L	221_L	1.792	0.97
58_V	85_V	1.783	0.97
289_L	371_L	1.752	0.97
3_P	68_V	1.746	0.97
551_T	556_P	1.738	0.97
79_L	91_A	1.728	0.97
291_T	315_I	1.727	0.97
47_F	51_A	1.720	0.96
362_A	395_F	1.712	0.96
536_V	543_G	1.666	0.96
530_F	533_V	1.661	0.96
128_I	192_I	1.660	0.96
17_A	46_L	1.657	0.96
217_I	624_G	1.650	0.96
550_V	587_L	1.649	0.95
583_I	615_A	1.639	0.95
508_S	607_K	1.624	0.95
534_K	547_T	1.620	0.95
403_A	406_L	1.615	0.95
529_T	549_G	1.613	0.95
176_L	225_L	1.613	0.95
413_R	417_D	1.612	0.95
376_H	384_I	1.612	0.95
304_A	307_S	1.611	0.95
151_L	154_F	1.608	0.95
527_R	554_G	1.593	0.95
157_E	569_T	1.591	0.95
14_L	138_L	1.583	0.94
406_L	494_L	1.583	0.94
2_M	56_V	1.583	0.94
129_M	189_A	1.570	0.94
127_A	131_M	1.553	0.94
564_K	575_T	1.543	0.94
230_A	302_V	1.542	0.94
44_W	108_F	1.542	0.94
61_F	75_S	1.541	0.94
18_L	134_V	1.522	0.93
178_Y	182_V	1.522	0.93
289_L	367_L	1.503	0.93
76_N	79_L	1.499	0.93
138_L	314_F	1.496	0.92
365_V	394_M	1.488	0.92
192_I	329_L	1.485	0.92
332_A	335_H	1.484	0.92
251_M	363_M	1.481	0.92
552_R	555_K	1.478	0.92
28_V	36_M	1.457	0.91
274_A	330_F	1.455	0.91
489_A	626_L	1.454	0.91
397_W	401_P	1.454	0.91
60_A	68_V	1.453	0.91
14_L	134_V	1.449	0.91
213_L	260_M	1.441	0.91
589_A	604_L	1.437	0.91
466_A	495_A	1.428	0.91
556_P	559_V	1.417	0.90
432_S	464_V	1.404	0.90
70_Y	79_L	1.404	0.90
181_Y	294_V	1.401	0.90
110_V	190_F	1.392	0.89
46_L	133_S	1.390	0.89
482_F	626_L	1.381	0.89
531_R	547_T	1.378	0.89
69_T	148_S	1.371	0.89
228_A	612_W	1.364	0.88
513_V	602_V	1.362	0.88
20_L	42_F	1.362	0.88
233_E	574_M	1.360	0.88
104_S	137_L	1.357	0.88
534_K	545_V	1.356	0.88
317_A	321_L	1.354	0.88
541_W	563_E	1.347	0.88
500_G	613_I	1.344	0.88
50_V	100_V	1.340	0.88
28_V	124_R	1.340	0.88
423_R	427_I	1.339	0.87
469_E	473_R	1.332	0.87
8_G	11_C	1.326	0.87
595_L	598_G	1.322	0.87
82_W	171_I	1.322	0.87
18_L	436_L	1.314	0.86
120_D	197_S	1.304	0.86
582_G	585_R	1.281	0.85
17_A	20_L	1.280	0.85
503_F	507_Y	1.277	0.85
566_Y	573_M	1.268	0.84
307_S	310_A	1.266	0.84
75_S	84_R	1.266	0.84
160_D	570_A	1.265	0.84
515_M	521_V	1.263	0.84
214_A	628_L	1.262	0.84
528_F	604_L	1.260	0.84
214_A	283_A	1.256	0.84
275_W	356_N	1.251	0.84
266_T	276_T	1.249	0.84
78_Q	157_E	1.246	0.83
317_A	320_V	1.232	0.83
433_T	440_L	1.231	0.83
24_P	39_S	1.222	0.82
40_R	122_V	1.220	0.82
51_A	105_G	1.214	0.82
393_T	397_W	1.214	0.82
217_I	221_L	1.211	0.82
259_L	280_A	1.209	0.81
87_A	171_I	1.207	0.81
128_I	329_L	1.203	0.81
437_S	453_V	1.202	0.81
428_I	432_S	1.200	0.81
560_L	589_A	1.194	0.81
19_L	38_S	1.193	0.81
372_L	376_H	1.193	0.81
514_R	599_A	1.184	0.80
216_W	257_T	1.181	0.80
78_Q	568_N	1.175	0.80
434_L	437_S	1.170	0.79
528_F	550_V	1.169	0.79
255_V	286_L	1.165	0.79
417_D	421_K	1.155	0.78
96_L	140_I	1.150	0.78
489_A	622_L	1.150	0.78
463_A	495_A	1.139	0.77
220_T	620_M	1.135	0.77
262_S	276_T	1.134	0.77
549_G	556_P	1.132	0.77
213_L	627_C	1.128	0.77
39_S	123_A	1.127	0.77
496_V	615_A	1.124	0.76
618_L	622_L	1.122	0.76
459_A	495_A	1.121	0.76
299_L	500_G	1.118	0.76
528_F	589_A	1.115	0.76
167_D	232_Y	1.106	0.75
549_G	559_V	1.102	0.75
98_L	179_M	1.102	0.75
64_N	70_Y	1.095	0.75
75_S	93_E	1.095	0.75
74_N	93_E	1.091	0.74
9_L	52_G	1.090	0.74
4_E	149_R	1.090	0.74
359_L	402_F	1.088	0.74
82_W	172_F	1.088	0.74
32_D	35_M	1.084	0.74
283_A	286_L	1.084	0.74
630_D	633_Y	1.081	0.74
262_S	275_W	1.078	0.73
493_G	620_M	1.078	0.73
354_A	405_L	1.073	0.73
228_A	586_D	1.072	0.73
272_F	353_L	1.067	0.73
227_S	241_F	1.066	0.72
532_D	546_A	1.065	0.72
212_T	260_M	1.064	0.72
527_R	553_D	1.059	0.72
464_V	467_I	1.057	0.72
467_I	471_A	1.049	0.71
565_R	576_E	1.036	0.70
60_A	71_V	1.033	0.70
19_L	35_M	1.031	0.70
91_A	170_L	1.027	0.70
79_L	160_D	1.025	0.69
585_R	606_Y	1.025	0.69
440_L	456_L	1.023	0.69
434_L	439_L	1.022	0.69
44_W	112_I	1.021	0.69
515_M	602_V	1.016	0.69
436_L	460_C	1.015	0.69
567_Y	572_S	1.013	0.69
132_V	284_F	1.013	0.69
517_S	532_D	1.012	0.68
532_D	547_T	1.010	0.68
217_I	625_L	1.006	0.68
27_G	36_M	1.005	0.68
550_V	557_E	1.005	0.68
459_A	463_A	1.005	0.68
540_N	565_R	1.004	0.68
510_E	605_Y	1.003	0.68
239_W	487_M	1.003	0.68
255_V	282_S	1.002	0.68
557_E	580_D	1.002	0.68
233_E	563_E	0.996	0.67
469_E	484_Y	0.990	0.67
55_L	260_M	0.987	0.67
107_T	129_M	0.986	0.66
61_F	161_L	0.985	0.66
160_D	590_A	0.984	0.66
502_A	505_Q	0.978	0.66
227_S	613_I	0.978	0.66
48_M	52_G	0.976	0.66
487_M	543_G	0.974	0.65
38_S	42_F	0.973	0.65
521_V	604_L	0.972	0.65
100_V	321_L	0.969	0.65
480_T	483_S	0.966	0.65
479_K	483_S	0.965	0.65
285_S	323_I	0.957	0.64
277_L	593_E	0.952	0.64
143_T	575_T	0.950	0.64
68_V	72_A	0.946	0.63
74_N	90_G	0.944	0.63
591_L	602_V	0.943	0.63
183_G	215_A	0.936	0.62
22_V	26_W	0.930	0.62
9_L	49_S	0.928	0.62
125_V	190_F	0.926	0.62
98_L	293_L	0.925	0.61
462_I	465_L	0.917	0.61
365_V	494_L	0.917	0.61
458_M	461_W	0.913	0.60
437_S	441_P	0.909	0.60
369_G	390_F	0.905	0.60
484_Y	488_V	0.905	0.60
365_V	378_Q	0.900	0.59
345_L	350_S	0.899	0.59
489_A	509_V	0.898	0.59
546_A	591_L	0.897	0.59
523_I	604_L	0.897	0.59
523_I	528_F	0.895	0.59
269_R	349_E	0.895	0.59
591_L	599_A	0.893	0.59
315_I	319_M	0.892	0.59
381_L	391_F	0.890	0.58
108_F	112_I	0.887	0.58
323_I	326_S	0.886	0.58
372_L	377_K	0.885	0.58
332_A	590_A	0.881	0.58
18_L	148_S	0.881	0.58
55_L	59_N	0.874	0.57
412_V	417_D	0.874	0.57
226_G	229_W	0.873	0.57
144_S	227_S	0.872	0.57
16_I	42_F	0.869	0.57
441_P	507_Y	0.868	0.57
61_F	71_V	0.868	0.57
2_M	59_N	0.867	0.56
174_P	305_F	0.866	0.56
550_V	560_L	0.866	0.56
14_L	18_L	0.861	0.56
198_G	632_R	0.860	0.56
173_H	303_H	0.859	0.56
19_L	42_F	0.859	0.56
346_W	351_L	0.858	0.56
14_L	137_L	0.858	0.56
286_L	627_C	0.855	0.55
372_L	397_W	0.851	0.55
106_W	183_G	0.851	0.55
551_T	557_E	0.851	0.55
564_K	573_M	0.851	0.55
630_D	634_R	0.850	0.55
86_A	130_G	0.848	0.55
247_N	370_T	0.848	0.55
354_A	358_L	0.847	0.55
486_G	627_C	0.847	0.55
170_L	232_Y	0.846	0.55
591_L	600_W	0.846	0.55
70_Y	76_N	0.845	0.54
224_V	504_S	0.845	0.54
485_W	488_V	0.843	0.54
471_A	474_I	0.841	0.54
232_Y	294_V	0.841	0.54
164_L	310_A	0.840	0.54
466_A	488_V	0.838	0.54
26_W	35_M	0.837	0.54
281_I	285_S	0.835	0.54
179_M	218_F	0.835	0.54
230_A	241_F	0.834	0.54
364_L	388_E	0.834	0.54
226_G	303_H	0.832	0.53
229_W	303_H	0.832	0.53
36_M	119_L	0.831	0.53
590_A	607_K	0.830	0.53
86_A	96_L	0.830	0.53
428_I	467_I	0.829	0.53
43_A	46_L	0.827	0.53
9_L	56_V	0.827	0.53
269_R	356_N	0.827	0.53
78_Q	591_L	0.826	0.53
50_V	443_L	0.821	0.52
92_H	241_F	0.821	0.52
47_F	101_L	0.820	0.52
57_L	161_L	0.819	0.52
37_A	363_M	0.819	0.52
66_F	75_S	0.817	0.52
11_C	15_G	0.817	0.52
199_R	501_I	0.816	0.52
529_T	547_T	0.816	0.52
513_V	521_V	0.815	0.52
165_L	303_H	0.815	0.52
35_M	127_A	0.813	0.52
365_V	390_F	0.812	0.52
474_I	478_T	0.811	0.51
43_A	107_T	0.810	0.51
73_S	159_R	0.808	0.51
61_F	87_A	0.807	0.51
448_V	452_T	0.806	0.51
526_Y	550_V	0.805	0.51
404_L	408_V	0.805	0.51
31_G	51_A	0.803	0.51
537_T	542_R	0.803	0.51
526_Y	587_L	0.801	0.51
426_L	443_L	0.801	0.51
461_W	465_L	0.801	0.51
7_N	11_C	0.800	0.50
251_M	255_V	0.800	0.50
26_W	30_R	0.800	0.50
552_R	556_P	0.799	0.50
251_M	283_A	0.798	0.50
61_F	91_A	0.798	0.50
245_V	303_H	0.797	0.50
535_E	544_G	0.796	0.50
178_Y	275_W	0.795	0.50
231_Y	246_E	0.795	0.50
44_W	48_M	0.794	0.50
169_G	294_V	0.794	0.50
459_A	499_V	0.793	0.50
436_L	499_V	0.793	0.50
284_F	290_G	0.790	0.50
174_P	238_G	0.790	0.50
54_F	91_A	0.790	0.50
55_L	404_L	0.788	0.49
262_S	355_N	0.788	0.49
232_Y	577_A	0.785	0.49
72_A	159_R	0.785	0.49
454_L	571_G	0.784	0.49
516_K	599_A	0.782	0.49
233_E	241_F	0.778	0.49
234_L	252_P	0.776	0.48
392_N	399_M	0.775	0.48
96_L	230_A	0.773	0.48
209_R	267_E	0.773	0.48
304_A	405_L	0.772	0.48
418_R	421_K	0.772	0.48
440_L	546_A	0.770	0.48
150_T	154_F	0.770	0.48
60_A	65_D	0.770	0.48
324_G	499_V	0.770	0.48
394_M	601_A	0.769	0.48
581_G	587_L	0.768	0.48
330_F	593_E	0.768	0.48
14_L	141_L	0.767	0.48
504_S	617_G	0.765	0.47
421_K	425_L	0.765	0.47
372_L	390_F	0.765	0.47
27_G	39_S	0.764	0.47
178_Y	540_N	0.764	0.47
87_A	91_A	0.763	0.47
110_V	125_V	0.763	0.47
404_L	457_A	0.761	0.47
395_F	399_M	0.759	0.47
124_R	197_S	0.758	0.47
611_R	617_G	0.758	0.47
552_R	557_E	0.758	0.47
343_N	415_G	0.756	0.47
223_I	565_R	0.756	0.47
167_D	241_F	0.754	0.46
527_R	551_T	0.754	0.46
363_M	438_L	0.752	0.46
58_V	87_A	0.752	0.46
533_V	600_W	0.751	0.46
215_A	347_S	0.750	0.46
546_A	602_V	0.749	0.46
67_T	150_T	0.749	0.46
532_D	559_V	0.749	0.46
102_L	179_M	0.748	0.46
430_F	433_T	0.747	0.46
104_S	617_G	0.746	0.46
462_I	495_A	0.746	0.46
70_Y	74_N	0.742	0.45
441_P	444_F	0.741	0.45
367_L	371_L	0.740	0.45
484_Y	487_M	0.737	0.45
139_F	308_D	0.735	0.45
174_P	303_H	0.735	0.45
174_P	231_Y	0.735	0.45
107_T	133_S	0.734	0.45
412_V	422_I	0.734	0.45
542_R	568_N	0.733	0.45
210_P	349_E	0.733	0.45
250_F	395_F	0.733	0.45
51_A	328_L	0.733	0.45
377_K	381_L	0.731	0.44
456_L	460_C	0.730	0.44
367_L	569_T	0.730	0.44
233_E	567_Y	0.729	0.44
346_W	422_I	0.728	0.44
150_T	492_L	0.728	0.44
64_N	75_S	0.727	0.44
466_A	492_L	0.727	0.44
239_W	505_Q	0.724	0.44
306_A	312_G	0.723	0.44
420_R	428_I	0.723	0.44
30_R	37_A	0.722	0.44
463_A	467_I	0.721	0.43
103_M	178_Y	0.719	0.43
21_S	127_A	0.719	0.43
233_E	565_R	0.719	0.43
404_L	454_L	0.718	0.43
81_V	84_R	0.718	0.43
344_A	492_L	0.717	0.43
7_N	141_L	0.717	0.43
584_T	587_L	0.716	0.43
307_S	577_A	0.711	0.43
589_A	625_L	0.711	0.43
62_V	84_R	0.711	0.43
623_G	627_C	0.710	0.42
376_H	380_G	0.710	0.42
239_W	501_I	0.709	0.42
493_G	616_G	0.708	0.42
173_H	226_G	0.708	0.42
173_H	229_W	0.708	0.42
541_W	565_R	0.707	0.42
429_A	433_T	0.707	0.42
228_A	611_R	0.706	0.42
107_T	523_I	0.705	0.42
200_L	277_L	0.704	0.42
558_T	580_D	0.702	0.42
56_V	104_S	0.702	0.42
340_R	378_Q	0.701	0.42
96_L	307_S	0.701	0.42
294_V	546_A	0.701	0.42
419_P	489_A	0.700	0.42
394_M	397_W	0.700	0.42
438_L	527_R	0.699	0.42
528_F	587_L	0.699	0.42
317_A	430_F	0.699	0.42
439_L	479_K	0.697	0.41
165_L	173_H	0.697	0.41
449_V	452_T	0.697	0.41
400_V	404_L	0.696	0.41
441_P	446_S	0.695	0.41
281_I	326_S	0.694	0.41
369_G	386_I	0.691	0.41
9_L	20_L	0.688	0.41
167_D	294_V	0.684	0.40
64_N	91_A	0.684	0.40
84_R	166_Q	0.684	0.40
62_V	404_L	0.683	0.40
181_Y	290_G	0.683	0.40
417_D	422_I	0.683	0.40
299_L	304_A	0.682	0.40
320_V	346_W	0.681	0.40
160_D	169_G	0.681	0.40
523_I	587_L	0.680	0.40
231_Y	238_G	0.680	0.40
377_K	380_G	0.679	0.40
354_A	492_L	0.679	0.40
499_V	528_F	0.678	0.40
80_P	565_R	0.677	0.40
245_V	305_F	0.677	0.40
98_L	564_K	0.677	0.40
143_T	307_S	0.677	0.40
382_G	385_S	0.676	0.40
14_L	85_V	0.676	0.40
51_A	54_F	0.676	0.40
243_D	261_H	0.675	0.39
243_D	491_H	0.675	0.39
261_H	491_H	0.675	0.39
25_L	124_R	0.675	0.39
621_A	625_L	0.674	0.39
20_L	43_A	0.673	0.39
178_Y	565_R	0.672	0.39
66_F	72_A	0.672	0.39
328_L	460_C	0.671	0.39
434_L	467_I	0.671	0.39
426_L	429_A	0.671	0.39
304_A	523_I	0.671	0.39
151_L	160_D	0.671	0.39
121_I	125_V	0.670	0.39
390_F	628_L	0.670	0.39
354_A	420_R	0.669	0.39
304_A	428_I	0.669	0.39
52_G	63_V	0.669	0.39
169_G	607_K	0.666	0.39
117_I	207_F	0.666	0.39
429_A	472_L	0.666	0.39
164_L	574_M	0.664	0.39
346_W	496_V	0.664	0.39
85_V	492_L	0.664	0.39
49_S	573_M	0.663	0.38
173_H	245_V	0.662	0.38
320_V	528_F	0.662	0.38
64_N	76_N	0.662	0.38
298_V	391_F	0.662	0.38
92_H	144_S	0.661	0.38
84_R	87_A	0.660	0.38
610_V	613_I	0.659	0.38
93_E	98_L	0.658	0.38
165_L	229_W	0.657	0.38
165_L	226_G	0.657	0.38
91_A	171_I	0.657	0.38
257_T	352_L	0.655	0.38
385_S	389_P	0.655	0.38
165_L	245_V	0.652	0.38
105_G	478_T	0.651	0.37
19_L	23_Y	0.651	0.37
273_K	413_R	0.650	0.37
14_L	26_W	0.649	0.37
140_I	523_I	0.648	0.37
76_N	91_A	0.648	0.37
217_I	628_L	0.648	0.37
535_E	542_R	0.647	0.37
239_W	600_W	0.646	0.37
172_F	467_I	0.646	0.37
529_T	532_D	0.646	0.37
448_V	453_V	0.645	0.37
427_I	431_I	0.644	0.37
104_S	431_I	0.644	0.37
33_A	435_V	0.643	0.37
81_V	157_E	0.643	0.37
172_F	218_F	0.643	0.37
251_M	367_L	0.643	0.37
192_I	326_S	0.642	0.37
75_S	92_H	0.642	0.37
231_Y	236_W	0.642	0.37
224_V	620_M	0.642	0.37
33_A	119_L	0.640	0.37
174_P	246_E	0.640	0.37
76_N	82_W	0.639	0.36
278_L	330_F	0.638	0.36
435_V	450_A	0.638	0.36
79_L	171_I	0.638	0.36
501_I	573_M	0.638	0.36
530_F	599_A	0.636	0.36
102_L	282_S	0.636	0.36
189_A	248_A	0.636	0.36
226_G	245_V	0.635	0.36
229_W	245_V	0.635	0.36
144_S	294_V	0.634	0.36
212_T	215_A	0.634	0.36
344_A	416_R	0.633	0.36
26_W	321_L	0.632	0.36
533_V	546_A	0.632	0.36
182_V	287_C	0.631	0.36
283_A	403_A	0.631	0.36
183_G	220_T	0.629	0.36
44_W	492_L	0.629	0.36
16_I	44_W	0.629	0.36
299_L	374_L	0.628	0.36
508_S	608_P	0.628	0.36
404_L	552_R	0.628	0.36
307_S	572_S	0.627	0.35
474_I	550_V	0.627	0.35
424_N	427_I	0.626	0.35
18_L	21_S	0.626	0.35
22_V	561_Y	0.626	0.35
232_Y	579_I	0.626	0.35
262_S	349_E	0.625	0.35
464_V	468_A	0.624	0.35
497_T	617_G	0.624	0.35
63_V	610_V	0.624	0.35
384_I	579_I	0.624	0.35
430_F	457_A	0.623	0.35
438_L	442_W	0.623	0.35
455_G	460_C	0.623	0.35
456_L	459_A	0.622	0.35
418_R	442_W	0.622	0.35
227_S	540_N	0.621	0.35
266_T	272_F	0.621	0.35
267_E	356_N	0.621	0.35
622_L	626_L	0.620	0.35
553_D	556_P	0.619	0.35
171_I	574_M	0.619	0.35
55_L	534_K	0.619	0.35
92_H	311_R	0.618	0.35
155_P	228_A	0.618	0.35
170_L	250_F	0.618	0.35
23_Y	127_A	0.618	0.35
168_P	171_I	0.618	0.35
386_I	390_F	0.617	0.35
408_V	418_R	0.617	0.35
447_K	452_T	0.617	0.35
513_V	604_L	0.615	0.34
233_E	564_K	0.615	0.34
497_T	620_M	0.614	0.34
429_A	438_L	0.614	0.34
351_L	354_A	0.613	0.34
293_L	315_I	0.612	0.34
250_F	254_L	0.612	0.34
513_V	626_L	0.610	0.34
204_Y	208_T	0.609	0.34
281_I	288_L	0.608	0.34
493_G	619_M	0.608	0.34
82_W	87_A	0.608	0.34
196_L	333_R	0.607	0.34
105_G	430_F	0.607	0.34
24_P	127_A	0.607	0.34
102_L	122_V	0.606	0.34
398_L	604_L	0.606	0.34
452_T	459_A	0.605	0.34
403_A	458_M	0.605	0.34
86_A	600_W	0.604	0.34
332_A	430_F	0.604	0.34
375_V	388_E	0.604	0.34
354_A	408_V	0.603	0.34
354_A	464_V	0.603	0.34
54_F	98_L	0.603	0.34
504_S	590_A	0.603	0.34
160_D	607_K	0.600	0.33
383_S	397_W	0.600	0.33
424_N	428_I	0.600	0.33
170_L	405_L	0.600	0.33
175_P	225_L	0.599	0.33
23_Y	38_S	0.598	0.33
127_A	196_L	0.598	0.33
168_P	289_L	0.598	0.33
166_Q	540_N	0.598	0.33
139_F	145_N	0.598	0.33
319_M	391_F	0.597	0.33
508_S	573_M	0.597	0.33
397_W	609_F	0.595	0.33
56_V	60_A	0.595	0.33
98_L	102_L	0.595	0.33
91_A	161_L	0.594	0.33
320_V	499_V	0.594	0.33
431_I	468_A	0.592	0.33
42_F	100_V	0.591	0.33
288_L	579_I	0.591	0.33
508_S	617_G	0.590	0.32
61_F	308_D	0.590	0.32
277_L	415_G	0.589	0.32
39_S	404_L	0.589	0.32
238_G	246_E	0.588	0.32
174_P	226_G	0.587	0.32
174_P	229_W	0.587	0.32
546_A	549_G	0.587	0.32
256_G	365_V	0.586	0.32
376_H	570_A	0.584	0.32
165_L	174_P	0.584	0.32
346_W	419_P	0.584	0.32
510_E	546_A	0.583	0.32
431_I	435_V	0.583	0.32
45_L	217_I	0.583	0.32
124_R	196_L	0.582	0.32
15_G	619_M	0.582	0.32
58_V	101_L	0.582	0.32
229_W	243_D	0.582	0.32
229_W	491_H	0.582	0.32
226_G	243_D	0.582	0.32
229_W	261_H	0.582	0.32
226_G	261_H	0.582	0.32
226_G	491_H	0.582	0.32
510_E	603_R	0.581	0.32
86_A	221_L	0.581	0.32
377_K	390_F	0.580	0.32
64_N	79_L	0.580	0.32
18_L	375_V	0.580	0.32
278_L	327_L	0.579	0.32
500_G	610_V	0.578	0.32
376_H	381_L	0.578	0.32
97_L	291_T	0.577	0.31
275_W	349_E	0.577	0.31
35_M	400_V	0.577	0.31
195_L	333_R	0.576	0.31
432_S	436_L	0.576	0.31
267_E	275_W	0.574	0.31
213_L	504_S	0.573	0.31
2_M	437_S	0.573	0.31
48_M	344_A	0.573	0.31
205_A	208_T	0.573	0.31
456_L	559_V	0.572	0.31
95_S	373_P	0.571	0.31
86_A	136_F	0.571	0.31
41_L	455_G	0.571	0.31
379_L	382_G	0.571	0.31
41_L	515_M	0.571	0.31
366_V	588_Y	0.570	0.31
571_G	582_G	0.570	0.31
438_L	443_L	0.570	0.31
571_G	613_I	0.569	0.31
266_T	270_A	0.569	0.31
76_N	171_I	0.569	0.31
74_N	371_L	0.569	0.31
26_W	468_A	0.569	0.31
179_M	264_A	0.568	0.31
406_L	498_I	0.568	0.31
18_L	532_D	0.567	0.31
438_L	444_F	0.567	0.31
189_A	470_A	0.566	0.31
364_L	431_I	0.566	0.31
48_M	535_E	0.566	0.31
104_S	107_T	0.566	0.31
463_A	622_L	0.566	0.31
390_F	394_M	0.565	0.31
241_F	592_G	0.564	0.30
431_I	434_L	0.563	0.30
59_N	556_P	0.563	0.30
267_E	349_E	0.562	0.30
90_G	308_D	0.562	0.30
23_Y	438_L	0.561	0.30
362_A	399_M	0.561	0.30
493_G	623_G	0.561	0.30
100_V	133_S	0.560	0.30
104_S	626_L	0.560	0.30
130_G	134_V	0.559	0.30
277_L	360_V	0.558	0.30
174_P	245_V	0.557	0.30
158_G	373_P	0.556	0.30
436_L	442_W	0.556	0.30
338_R	430_F	0.556	0.30
361_A	385_S	0.556	0.30
64_N	87_A	0.555	0.30
453_V	458_M	0.555	0.30
365_V	397_W	0.554	0.30
580_D	583_I	0.553	0.30
346_W	464_V	0.553	0.30
188_F	284_F	0.552	0.30
461_W	464_V	0.552	0.30
487_M	600_W	0.551	0.30
78_Q	338_R	0.551	0.30
17_A	585_R	0.551	0.30
278_L	353_L	0.551	0.30
46_L	49_S	0.550	0.29
13_A	20_L	0.550	0.29
550_V	589_A	0.549	0.29
561_Y	578_A	0.548	0.29
358_L	402_F	0.548	0.29
499_V	609_F	0.547	0.29
190_F	204_Y	0.547	0.29
591_L	618_L	0.547	0.29
92_H	308_D	0.546	0.29
50_V	101_L	0.546	0.29
372_L	383_S	0.546	0.29
508_S	611_R	0.546	0.29
456_L	553_D	0.545	0.29
249_S	304_A	0.544	0.29
434_L	443_L	0.544	0.29
426_L	439_L	0.543	0.29
582_G	609_F	0.543	0.29
468_A	472_L	0.542	0.29
121_I	354_A	0.542	0.29
55_L	321_L	0.542	0.29
279_L	370_T	0.541	0.29
400_V	433_T	0.541	0.29
167_D	308_D	0.540	0.29
196_L	334_G	0.540	0.29
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433_T	508_S	0.539	0.29
423_R	555_K	0.539	0.29
342_N	390_F	0.539	0.29
456_L	499_V	0.539	0.29
43_A	111_A	0.538	0.29
502_A	506_N	0.538	0.29
99_W	252_P	0.538	0.29
407_G	495_A	0.538	0.29
104_S	133_S	0.537	0.28
466_A	470_A	0.537	0.28
458_M	462_I	0.537	0.28
69_T	150_T	0.536	0.28
80_P	178_Y	0.535	0.28
11_C	553_D	0.534	0.28
188_F	623_G	0.533	0.28
548_I	561_Y	0.532	0.28
547_T	553_D	0.532	0.28
41_L	45_L	0.532	0.28
515_M	601_A	0.531	0.28
55_L	419_P	0.531	0.28
373_P	588_Y	0.531	0.28
135_G	314_F	0.531	0.28
354_A	421_K	0.530	0.28
410_P	610_V	0.530	0.28
439_L	626_L	0.530	0.28
67_T	149_R	0.529	0.28
392_N	505_Q	0.529	0.28
64_N	566_Y	0.529	0.28
18_L	354_A	0.528	0.28
248_A	591_L	0.528	0.28
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378_Q	610_V	0.527	0.28
420_R	424_N	0.527	0.28
110_V	208_T	0.526	0.28
238_G	305_F	0.526	0.28
569_T	572_S	0.526	0.28
92_H	294_V	0.526	0.28
70_Y	96_L	0.526	0.28
103_M	291_T	0.525	0.28
172_F	485_W	0.525	0.28
391_F	554_G	0.525	0.28
432_S	454_L	0.525	0.28
459_A	465_L	0.525	0.28
79_L	106_W	0.524	0.28
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79_L	82_W	0.524	0.28
496_V	549_G	0.524	0.28
390_F	501_I	0.524	0.28
250_F	536_V	0.523	0.27
555_K	558_T	0.523	0.27
456_L	536_V	0.523	0.27
100_V	571_G	0.523	0.27
19_L	464_V	0.522	0.27
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291_T	319_M	0.521	0.27
92_H	178_Y	0.521	0.27
469_E	480_T	0.521	0.27
517_S	544_G	0.521	0.27
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240_W	491_H	0.520	0.27
240_W	243_D	0.520	0.27
17_A	622_L	0.520	0.27
297_G	302_V	0.519	0.27
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299_L	359_L	0.518	0.27
257_T	286_L	0.517	0.27
71_V	87_A	0.517	0.27
22_V	332_A	0.517	0.27
85_V	481_T	0.516	0.27
497_T	613_I	0.516	0.27
197_S	200_L	0.516	0.27
257_T	407_G	0.515	0.27
521_V	558_T	0.515	0.27
63_V	442_W	0.515	0.27
281_I	501_I	0.515	0.27
114_S	122_V	0.514	0.27
180_G	247_N	0.514	0.27
38_S	41_L	0.513	0.27
558_T	587_L	0.513	0.27
106_W	160_D	0.513	0.27
436_L	537_T	0.512	0.27
609_F	613_I	0.512	0.27
140_I	606_Y	0.511	0.27
135_G	169_G	0.511	0.27
478_T	531_R	0.510	0.27
352_L	355_N	0.510	0.27
368_L	384_I	0.510	0.27
67_T	218_F	0.510	0.27
174_P	297_G	0.509	0.26
293_L	298_V	0.509	0.26
386_I	389_P	0.508	0.26
47_F	104_S	0.508	0.26
186_V	608_P	0.508	0.26
413_R	418_R	0.507	0.26
243_D	303_H	0.507	0.26
303_H	491_H	0.507	0.26
261_H	303_H	0.507	0.26
18_L	451_M	0.506	0.26
91_A	266_T	0.506	0.26
85_V	418_R	0.506	0.26
45_L	48_M	0.506	0.26
234_L	301_S	0.506	0.26
397_W	562_A	0.505	0.26
106_W	179_M	0.505	0.26
25_L	131_M	0.505	0.26
145_N	292_F	0.505	0.26
65_D	93_E	0.503	0.26
285_S	326_S	0.503	0.26
92_H	232_Y	0.503	0.26
112_I	456_L	0.502	0.26
174_P	234_L	0.502	0.26
487_M	501_I	0.501	0.26
53_A	140_I	0.501	0.26
43_A	470_A	0.501	0.26
44_W	527_R	0.501	0.26
530_F	548_I	0.500	0.26

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2cfqA	1	0.5951	51.8	0.981	Contact Map
1q16C	2	0.1947	15.5	0.985	Contact Map
3wdoA	1	0.6244	13.8	0.986	Contact Map
3cfuA	1	0.187	10.7	0.986	Contact Map
2mfrA	1	0.0881	7.2	0.987	Contact Map
4p6vD	1	0.2612	7.1	0.987	Contact Map
4knfA	3	0.0726	7.1	0.987	Contact Map
3mceA	2	0.0943	6.9	0.987	Contact Map
4xtlA	1	0.0989	6.9	0.987	Contact Map
3qbgA	3	0.0835	6.8	0.987	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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