GREMLIN Database
NDPA - Nucleoid-associated protein YejK
UniProt: P33920 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG12048
Length: 335 (328)
Sequences: 407 (284)
Seq/√Len: 15.7

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
207_D266_Y5.3361.00
76_D79_A4.6291.00
204_A266_Y4.5321.00
307_W324_R4.3591.00
81_S105_F3.8001.00
107_H114_E3.6281.00
9_A78_L3.6111.00
26_R134_D3.5971.00
11_H81_S3.1690.99
80_F84_A3.1450.99
319_T324_R2.9540.98
169_F188_A2.7870.97
312_D324_R2.6890.96
320_P323_L2.6760.96
39_M127_M2.5180.95
7_Q29_L2.4790.94
71_R158_E2.4480.94
70_Q107_H2.4020.93
77_F182_F2.3170.92
147_D188_A2.3070.92
308_D311_T2.3040.91
257_F261_A2.2890.91
11_H30_L2.2870.91
91_E94_K2.2500.90
57_F166_Y2.2480.90
47_Y168_T2.1780.89
167_L185_F2.1690.89
219_R272_F2.1420.88
30_L47_Y2.0390.85
153_D195_K2.0280.85
287_G323_L1.9910.84
204_A207_D1.9720.83
77_F187_G1.9690.83
230_C246_S1.9310.82
88_L185_F1.9220.82
77_F101_G1.9110.81
325_D329_R1.9100.81
115_Y151_R1.8080.77
153_D193_N1.8050.77
172_G185_F1.7940.77
23_L89_R1.7910.77
296_F320_P1.7860.77
55_G167_L1.7810.76
173_R327_L1.7790.76
51_N54_Y1.7510.75
169_F182_F1.7490.75
10_L126_S1.7220.74
141_L300_L1.7150.74
294_I319_T1.7110.73
103_V120_V1.6920.73
167_L188_A1.6710.72
201_L268_L1.6600.71
34_E124_L1.6580.71
177_K285_F1.6420.70
149_V188_A1.6330.70
10_L129_V1.6140.69
69_L74_E1.6120.69
47_Y128_R1.5830.67
67_L154_L1.5750.67
202_L205_V1.5200.64
130_N134_D1.5180.64
126_S276_R1.5020.63
165_R268_L1.4910.62
301_L314_L1.4870.62
149_V170_L1.4850.62
294_I305_I1.4810.62
295_N320_P1.4710.61
126_S140_Y1.4620.61
85_T208_F1.4440.60
37_V41_A1.4360.59
5_I106_C1.4210.59
25_L305_I1.4180.58
133_L169_F1.4090.58
171_K178_V1.4070.58
68_R71_R1.3950.57
308_D320_P1.3910.57
29_L78_L1.3780.56
282_L297_D1.3660.56
33_T152_I1.3580.55
23_L85_T1.3510.55
37_V152_I1.3460.54
120_V185_F1.3420.54
9_A29_L1.3410.54
314_L327_L1.3370.54
52_K172_G1.3120.52
311_T315_T1.2950.51
204_A294_I1.2850.51
26_R30_L1.2820.51
206_D223_R1.2790.51
304_R318_G1.2690.50
78_L194_A1.2670.50
165_R185_F1.2650.50
102_F129_V1.2600.49
3_L274_A1.2530.49
135_I148_I1.2470.49
69_L280_R1.2420.48
289_G318_G1.2390.48
118_V143_I1.2230.47
107_H154_L1.2220.47
79_A82_R1.2200.47
134_D305_I1.2170.47
92_L103_V1.2120.47
167_L186_L1.1970.46
121_L220_Q1.1770.45
30_L167_L1.1760.45
177_K181_F1.1720.44
100_G181_F1.1620.44
313_T318_G1.1610.44
62_E66_T1.1540.43
101_G187_G1.1500.43
287_G320_P1.1450.43
10_L276_R1.1400.43
233_Q245_L1.1360.42
296_F307_W1.1280.42
141_L149_V1.1270.42
98_A181_F1.1270.42
133_L150_A1.1200.41
113_V155_T1.1190.41
269_E273_P1.1160.41
212_A294_I1.1150.41
246_S250_A1.1150.41
130_N136_N1.1100.41
43_L62_E1.1100.41
83_A324_R1.1080.41
26_R121_L1.1050.41
33_T142_D1.1010.40
13_L244_S1.1000.40
147_D181_F1.0880.40
8_I40_V1.0870.40
34_E242_L1.0790.39
47_Y54_Y1.0780.39
108_Y170_L1.0760.39
242_L283_T1.0740.39
307_W314_L1.0700.39
100_G122_S1.0660.39
176_R322_N1.0620.38
78_L81_S1.0590.38
15_K55_G1.0530.38
50_K273_P1.0500.38
68_R157_W1.0490.38
15_K98_A1.0490.38
182_F188_A1.0490.38
70_Q125_S1.0450.37
201_L297_D1.0360.37
107_H187_G1.0340.37
162_E195_K1.0310.37
185_F268_L1.0270.36
150_A271_S1.0220.36
47_Y227_Y1.0190.36
292_L298_A1.0160.36
123_N261_A1.0160.36
152_I305_I1.0140.36
47_Y55_G1.0130.36
134_D279_L1.0130.36
148_I185_F1.0100.36
247_K300_L1.0070.35
122_S148_I1.0040.35
226_V279_L1.0010.35
294_I316_I0.9990.35
181_F198_N0.9990.35
91_E186_L0.9970.35
256_S259_E0.9970.35
119_A146_A0.9950.35
229_Y233_Q0.9880.34
71_R303_E0.9850.34
197_Q260_F0.9720.34
81_S129_V0.9710.33
122_S181_F0.9700.33
70_Q208_F0.9680.33
29_L263_E0.9650.33
127_M167_L0.9590.33
208_F256_S0.9570.33
292_L300_L0.9550.33
141_L320_P0.9490.32
157_W170_L0.9480.32
280_R290_G0.9440.32
144_N215_D0.9430.32
8_I81_S0.9400.32
145_H283_T0.9400.32
48_S180_D0.9400.32
5_I11_H0.9380.32
114_E131_E0.9380.32
151_R282_L0.9360.32
5_I127_M0.9320.32
295_N323_L0.9300.31
15_K148_I0.9290.31
21_L284_K0.9270.31
81_S161_P0.9250.31
108_Y169_F0.9200.31
108_Y181_F0.9190.31
172_G178_V0.9180.31
257_F273_P0.9160.31
185_F262_A0.9140.31
9_A319_T0.9110.31
29_L72_Q0.9100.30
67_L157_W0.9090.30
117_L188_A0.9030.30
152_I265_G0.8990.30
43_L221_N0.8980.30
47_Y139_H0.8970.30
73_G158_E0.8930.30
39_M219_R0.8870.29
12_Q274_A0.8870.29
65_Q242_L0.8860.29
76_D310_A0.8850.29
6_N109_R0.8850.29
62_E93_A0.8850.29
10_L13_L0.8770.29
178_V275_D0.8760.29
146_A307_W0.8750.29
3_L292_L0.8670.28
121_L217_A0.8640.28
124_L305_I0.8620.28
160_N280_R0.8570.28
33_T221_N0.8570.28
254_E274_A0.8540.28
287_G295_N0.8540.28
138_T152_I0.8490.28
245_L327_L0.8450.27
173_R314_L0.8440.27
72_Q158_E0.8410.27
62_E146_A0.8400.27
55_G242_L0.8400.27
5_I41_A0.8380.27
321_P329_R0.8370.27
208_F219_R0.8370.27
150_A191_G0.8360.27
197_Q268_L0.8350.27
212_A256_S0.8330.27
183_M240_I0.8330.27
205_V226_V0.8290.27
114_E171_K0.8280.27
17_D60_E0.8280.27
135_I185_F0.8260.27
223_R269_E0.8250.26
5_I242_L0.8240.26
169_F187_G0.8230.26
195_K290_G0.8180.26
104_L121_L0.8170.26
208_F264_K0.8170.26
323_L327_L0.8150.26
47_Y104_L0.8140.26
234_L274_A0.8100.26
62_E129_V0.8060.26
7_Q94_K0.8030.26
210_A285_F0.7980.25
122_S147_D0.7970.25
83_A86_G0.7950.25
268_L272_F0.7950.25
103_V183_M0.7950.25
144_N196_A0.7940.25
301_L311_T0.7910.25
198_N318_G0.7880.25
15_K21_L0.7870.25
133_L182_F0.7870.25
143_I252_V0.7860.25
52_K177_K0.7860.25
26_R133_L0.7830.25
121_L232_E0.7830.25
7_Q283_T0.7810.25
47_Y169_F0.7800.25
30_L316_I0.7780.24
5_I100_G0.7780.24
99_D181_F0.7740.24
174_V188_A0.7730.24
34_E157_W0.7730.24
152_I167_L0.7710.24
189_S211_E0.7710.24
64_A186_L0.7700.24
118_V219_R0.7680.24
290_G297_D0.7660.24
155_T249_L0.7660.24
48_S292_L0.7630.24
98_A315_T0.7620.24
308_D313_T0.7610.24
240_I279_L0.7560.24
309_P328_Q0.7550.23
185_F188_A0.7540.23
81_S145_H0.7540.23
268_L318_G0.7520.23
132_N293_T0.7480.23
114_E308_D0.7460.23
97_F273_P0.7450.23
100_G242_L0.7440.23
208_F257_F0.7440.23
58_S189_S0.7430.23
224_Q316_I0.7430.23
71_R205_V0.7420.23
147_D167_L0.7410.23
216_K226_V0.7400.23
285_F327_L0.7400.23
141_L171_K0.7400.23
263_E272_F0.7330.23
7_Q286_A0.7330.23
121_L196_A0.7310.22
123_N128_R0.7300.22
52_K170_L0.7280.22
87_R167_L0.7210.22
141_L279_L0.7190.22
48_S107_H0.7150.22
155_T279_L0.7110.22
21_L197_Q0.7100.22
108_Y257_F0.7090.22
9_A232_E0.7090.22
92_L280_R0.7080.22
319_T327_L0.7080.22
189_S240_I0.7060.22
197_Q214_L0.7050.21
304_R312_D0.7040.21
208_F316_I0.7030.21
158_E311_T0.7020.21
221_N301_L0.7020.21
108_Y188_A0.7010.21
223_R267_E0.7000.21
15_K283_T0.6990.21
5_I159_T0.6970.21
296_F323_L0.6930.21
285_F325_D0.6920.21
120_V148_I0.6900.21
16_R100_G0.6880.21
80_F121_L0.6830.21
242_L288_S0.6800.21
297_D301_L0.6790.20
185_F298_A0.6790.20
235_Q240_I0.6780.20
288_S293_T0.6770.20
40_V106_C0.6760.20
208_F304_R0.6750.20
307_W328_Q0.6740.20
37_V67_L0.6740.20
104_L211_E0.6720.20
223_R293_T0.6720.20
121_L287_G0.6710.20
80_F90_D0.6710.20
179_A186_L0.6710.20
63_L92_L0.6690.20
259_E303_E0.6660.20
66_T240_I0.6660.20
12_Q147_D0.6650.20
296_F300_L0.6630.20
118_V193_N0.6600.20
159_T325_D0.6600.20
216_K305_I0.6600.20
293_T305_I0.6590.20
150_A189_S0.6590.20
105_F206_D0.6590.20
107_H129_V0.6580.20
8_I43_L0.6570.20
94_K97_F0.6570.20
13_L305_I0.6560.20
101_G166_Y0.6540.20
47_Y171_K0.6540.20
3_L6_N0.6520.19
149_V166_Y0.6510.19
128_R136_N0.6510.19
69_L314_L0.6490.19
250_A257_F0.6480.19
210_A218_E0.6480.19
157_W251_G0.6480.19
191_G273_P0.6450.19
88_L120_V0.6410.19
291_G300_L0.6390.19
162_E249_L0.6380.19
91_E102_F0.6360.19
170_L175_G0.6340.19
67_L105_F0.6330.19
172_G181_F0.6270.19
52_K147_D0.6250.19
244_S247_K0.6240.19
234_L276_R0.6220.18
147_D185_F0.6200.18
18_E328_Q0.6190.18
47_Y51_N0.6190.18
49_A143_I0.6150.18
16_R20_N0.6140.18
85_T226_V0.6130.18
13_L186_L0.6130.18
217_A317_K0.6120.18
36_V123_N0.6120.18
197_Q269_E0.6110.18
147_D183_M0.6110.18
21_L257_F0.6100.18
94_K303_E0.6070.18
111_L289_G0.6060.18
243_K258_T0.6050.18
208_F292_L0.6050.18
101_G182_F0.6040.18
69_L86_G0.6040.18
198_N275_D0.6010.18
147_D300_L0.6010.18
43_L279_L0.6010.18
55_G106_C0.6000.18
47_Y175_G0.6000.18
30_L119_A0.5980.18
10_L214_L0.5980.18
188_A201_L0.5950.18
307_W312_D0.5920.17
141_L201_L0.5920.17
140_Y239_E0.5910.17
115_Y153_D0.5910.17
73_G270_E0.5910.17
58_S61_S0.5890.17
27_D162_E0.5880.17
293_T323_L0.5870.17
180_D184_D0.5850.17
181_F322_N0.5850.17
33_T243_K0.5830.17
13_L37_V0.5830.17
28_S253_S0.5830.17
148_I197_Q0.5830.17
128_R327_L0.5820.17
206_D272_F0.5810.17
316_I326_Q0.5800.17
10_L168_T0.5800.17
151_R291_G0.5780.17
51_N275_D0.5780.17
63_L189_S0.5770.17
27_D134_D0.5750.17
218_E253_S0.5740.17
100_G170_L0.5740.17
128_R139_H0.5730.17
18_E43_L0.5720.17
177_K325_D0.5720.17
118_V186_L0.5720.17
188_A240_I0.5700.17
12_Q23_L0.5690.17
34_E244_S0.5690.17
99_D162_E0.5690.17
18_E254_E0.5660.17
46_V143_I0.5660.17
50_K179_A0.5640.17
301_L320_P0.5640.17
135_I192_L0.5620.16
51_N105_F0.5580.16
60_E319_T0.5570.16
235_Q309_P0.5540.16
56_L239_E0.5540.16
150_A242_L0.5540.16
273_P289_G0.5530.16
62_E167_L0.5530.16
7_Q35_T0.5520.16
102_F327_L0.5470.16
20_N114_E0.5460.16
221_N224_Q0.5460.16
8_I294_I0.5450.16
186_L252_V0.5440.16
25_L258_T0.5430.16
31_E83_A0.5430.16
54_Y230_C0.5410.16
5_I125_S0.5410.16
25_L71_R0.5400.16
178_V181_F0.5390.16
230_C327_L0.5390.16
140_Y268_L0.5380.16
315_T324_R0.5360.16
285_F323_L0.5350.16
64_A145_H0.5350.16
209_T240_I0.5330.16
47_Y186_L0.5280.15
21_L155_T0.5280.15
224_Q228_S0.5270.15
142_D321_P0.5260.15
84_A107_H0.5240.15
103_V241_E0.5230.15
298_A307_W0.5220.15
304_R316_I0.5210.15
67_L257_F0.5180.15
202_L323_L0.5180.15
33_T305_I0.5170.15
119_A275_D0.5160.15
312_D318_G0.5140.15
28_S103_V0.5130.15
288_S310_A0.5130.15
211_E280_R0.5130.15
147_D170_L0.5110.15
33_T303_E0.5110.15
177_K180_D0.5100.15
169_F298_A0.5090.15
80_F232_E0.5070.15
177_K288_S0.5070.15
36_V107_H0.5070.15
257_F292_L0.5070.15
183_M271_S0.5060.15
239_E271_S0.5060.15
193_N257_F0.5050.15
10_L102_F0.5050.15
57_F136_N0.5050.15
186_L191_G0.5050.15
54_Y222_V0.5050.15
51_N58_S0.5040.15
51_N120_V0.5010.15
10_L29_L0.5000.15
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3h87C 3 0.0716 64.6 0.958 Contact Map
1mntA 2 0.0806 44.7 0.963 Contact Map
1bazA 4 0.0806 37.7 0.964 Contact Map
1nlaA 2 0.0896 32.6 0.965 Contact Map
1u9pA 1 0.1045 28.9 0.966 Contact Map
3qoqA 3 0.0896 19.3 0.969 Contact Map
2np2A 2 0.2806 19 0.969 Contact Map
3elgA 1 0.2716 18.1 0.969 Contact Map
2ay0A 2 0.0746 18.1 0.969 Contact Map
4jtmA 2 0.1463 17.9 0.969 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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