FEOB - ECOLI - GREMLIN Contacts

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FEOB - Ferrous iron transport protein B

UniProt:	P33650	Sequences: MKKLTIGLIGNPNSGKTTLFNQLTGSRQRVGNWAGVTVERKEGQFSTTDHQVTLVDLPGTYSLTTISSQTSLDEQIACHYILSGDADLLINVVDASNLERNLYLTLQLLELGIPCIVALNMLDIAEKQNIRIEIDALSARLGCPVIPLVSTRGRGIEALKLAIDRYKANENVELVHYAQPLLNEADSLAKVMPSDIPLKQRRWLGLQMLEGDIYSRAYAGEASQHLDAALARLRNEMDDPALHIADARYQCIAAICDVVSNTLTAEPSRFTTAVDKIVLNRFLGLPIFLFVMYLMFLLAINIGGALQPLFDVGSVALFVHGIQWIGYTLHFPDWLTIFLAQGLGGGINTVLPLVPQIGMMYLFLSFLEDSGYMARAAFVMDRLMQALGLPGKSFVPLIVGFGCNVPSVMGARTLDAPRERLMTIMMAPFMSCGARLAIFAVFAAAFFGQNGALAVFSLYMLGIVMAVLTGLMLKYTIMRGEATPFVMELPVYHVPHVKSLIIQTWQRLKGFVLRAGKVIIIVSIFLSAFNSFSLSGKIVDNINDSALASVSRVITPVFKPIGVHEDNWQATVGLFTGAMAKEVVVGTLNTLYTAENIQDEEFNPAEFNLGEELFSAIDETWQSLKDTFSLSVLMNPIEASKGDGEMGTGAMGVMDQKFGSAAAAYSYLIFVLLYVPCISVMGAIARESSRGWMGFSILWGLNIAYSLATLFYQVASYSQHPTYSLVCILAVILFNIVVIGLLRRARSRVDIELLATRKSVSSCCAASTTGDCH	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG12102
Length:	773 (591)
Sequences:	1880 (1218)
Seq/√Len:	50.1

ECOLI - FEOB

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
126_E	154_R	5.769	1.00
42_E	53_T	5.730	1.00
182_L	202_R	4.952	1.00
280_N	283_L	4.838	1.00
117_V	143_C	4.826	1.00
308_P	311_D	4.360	1.00
91_N	105_T	4.193	1.00
140_R	258_V	4.075	1.00
96_S	124_I	3.702	1.00
358_G	508_L	3.593	1.00
304_G	308_P	3.563	1.00
136_A	139_A	3.508	1.00
274_V	278_V	3.483	1.00
90_I	163_I	3.470	1.00
19_L	148_L	3.179	1.00
298_L	363_F	3.138	1.00
133_E	136_A	3.074	1.00
79_H	83_S	3.060	1.00
93_V	117_V	2.974	1.00
95_A	119_L	2.895	1.00
321_G	325_I	2.736	1.00
339_L	343_L	2.615	1.00
400_G	407_S	2.602	1.00
6_I	163_I	2.540	1.00
311_D	315_V	2.535	1.00
207_Q	210_E	2.526	1.00
285_L	289_L	2.485	1.00
393_S	423_T	2.476	1.00
125_A	132_I	2.461	1.00
322_I	344_G	2.442	1.00
293_Y	452_A	2.435	1.00
231_A	235_N	2.412	1.00
468_L	472_M	2.409	1.00
392_K	415_D	2.401	1.00
509_K	513_L	2.398	1.00
184_E	229_A	2.393	1.00
162_A	165_R	2.381	1.00
136_A	140_R	2.363	1.00
498_K	502_I	2.339	1.00
47_T	161_L	2.329	1.00
577_G	584_V	2.328	1.00
207_Q	212_D	2.282	1.00
289_L	460_M	2.254	1.00
211_G	227_D	2.249	1.00
98_L	260_S	2.244	1.00
429_F	465_M	2.243	1.00
302_I	359_M	2.145	1.00
28_Q	43_G	2.125	1.00
187_S	229_A	2.111	1.00
124_I	493_H	2.104	1.00
134_I	147_P	2.089	1.00
337_I	341_Q	2.082	1.00
325_I	328_T	2.076	1.00
362_L	366_F	2.064	1.00
252_I	256_C	2.032	1.00
558_F	571_T	2.020	1.00
429_F	469_T	2.009	1.00
471_L	475_Y	1.984	1.00
48_T	161_L	1.975	1.00
443_A	451_G	1.974	0.99
126_E	131_R	1.966	0.99
336_T	340_A	1.959	0.99
5_T	53_T	1.943	0.99
296_F	401_F	1.931	0.99
290_F	294_L	1.929	0.99
20_F	43_G	1.926	0.99
326_G	339_L	1.922	0.99
22_Q	156_I	1.920	0.99
269_R	272_T	1.918	0.99
404_N	428_P	1.911	0.99
335_L	339_L	1.903	0.99
4_L	167_K	1.885	0.99
429_F	473_L	1.870	0.99
307_Q	352_P	1.870	0.99
138_S	144_P	1.868	0.99
553_V	556_P	1.866	0.99
404_N	408_V	1.835	0.99
313_G	316_A	1.830	0.99
555_T	571_T	1.826	0.99
122_L	125_A	1.821	0.99
125_A	130_I	1.809	0.99
323_Q	327_Y	1.793	0.99
97_N	101_N	1.791	0.99
354_V	508_L	1.769	0.99
438_I	584_V	1.763	0.99
550_V	553_V	1.761	0.99
298_L	359_M	1.756	0.99
431_S	439_F	1.754	0.99
270_F	274_V	1.752	0.99
311_D	352_P	1.749	0.99
24_T	28_Q	1.742	0.99
304_G	307_Q	1.737	0.99
457_S	461_L	1.737	0.99
315_V	320_H	1.727	0.99
81_I	113_I	1.724	0.99
106_L	251_C	1.722	0.99
45_F	160_K	1.693	0.98
126_E	147_P	1.693	0.98
180_P	236_E	1.692	0.98
443_A	455_V	1.689	0.98
417_P	421_L	1.684	0.98
185_A	206_L	1.679	0.98
334_W	532_F	1.676	0.98
431_S	462_G	1.658	0.98
504_T	508_L	1.650	0.98
452_A	456_F	1.648	0.98
543_N	552_R	1.641	0.98
203_W	215_S	1.635	0.98
323_Q	336_T	1.634	0.98
20_F	24_T	1.620	0.98
469_T	473_L	1.618	0.98
105_T	108_L	1.596	0.98
183_N	187_S	1.590	0.98
20_F	28_Q	1.558	0.97
103_Y	249_Y	1.555	0.97
533_S	536_G	1.553	0.97
461_L	464_V	1.553	0.97
19_L	150_S	1.543	0.97
401_F	430_M	1.535	0.97
119_L	134_I	1.534	0.97
437_A	441_V	1.529	0.97
162_A	166_Y	1.523	0.97
293_Y	453_L	1.515	0.97
410_G	413_T	1.510	0.97
404_N	427_A	1.508	0.97
362_L	504_T	1.505	0.97
50_H	168_A	1.497	0.97
24_T	43_G	1.487	0.96
90_I	159_L	1.484	0.96
122_L	147_P	1.482	0.96
92_V	148_L	1.477	0.96
497_V	501_I	1.471	0.96
327_Y	336_T	1.465	0.96
326_G	330_H	1.441	0.96
297_L	301_N	1.440	0.96
117_V	145_V	1.440	0.96
157_E	161_L	1.438	0.96
358_G	504_T	1.428	0.95
453_L	457_S	1.418	0.95
118_A	147_P	1.412	0.95
573_G	588_L	1.408	0.95
341_Q	345_G	1.407	0.95
185_A	209_L	1.406	0.95
132_I	260_S	1.400	0.95
306_L	310_F	1.396	0.95
6_I	88_L	1.392	0.95
117_V	141_L	1.384	0.95
354_V	512_V	1.384	0.95
577_G	581_K	1.382	0.95
517_K	521_I	1.381	0.95
186_D	190_K	1.369	0.94
79_H	214_Y	1.369	0.94
8_L	54_L	1.365	0.94
146_I	162_A	1.357	0.94
526_L	579_M	1.356	0.94
340_A	344_G	1.350	0.94
187_S	190_K	1.349	0.94
11_N	17_T	1.345	0.94
325_I	329_L	1.339	0.94
366_F	494_V	1.335	0.93
438_I	588_L	1.331	0.93
116_I	163_I	1.330	0.93
473_L	477_I	1.323	0.93
443_A	454_A	1.311	0.93
165_R	169_N	1.304	0.93
185_A	188_L	1.303	0.93
448_G	451_G	1.298	0.93
179_Q	183_N	1.291	0.92
351_L	512_V	1.291	0.92
523_S	586_G	1.282	0.92
181_L	244_I	1.277	0.92
109_L	115_C	1.277	0.92
108_L	115_C	1.274	0.92
118_A	159_L	1.273	0.92
227_D	231_A	1.272	0.92
251_C	255_I	1.268	0.92
178_A	247_A	1.265	0.92
401_F	431_S	1.259	0.91
78_C	212_D	1.259	0.91
533_S	537_K	1.257	0.91
387_L	467_V	1.248	0.91
5_T	55_V	1.247	0.91
135_D	139_A	1.242	0.91
45_F	54_L	1.240	0.91
319_V	340_A	1.240	0.91
39_E	63_L	1.238	0.91
160_K	163_I	1.231	0.90
33_W	455_V	1.229	0.90
92_V	118_A	1.227	0.90
382_R	386_A	1.221	0.90
533_S	538_I	1.218	0.90
187_S	191_V	1.218	0.90
380_M	384_M	1.218	0.90
576_T	587_T	1.208	0.90
55_V	80_Y	1.206	0.89
26_S	30_V	1.204	0.89
533_S	539_V	1.197	0.89
268_S	276_K	1.196	0.89
316_A	320_H	1.189	0.89
186_D	189_A	1.188	0.89
352_P	356_Q	1.188	0.89
369_D	503_Q	1.186	0.89
136_A	258_V	1.180	0.88
554_I	557_V	1.180	0.88
348_N	527_S	1.177	0.88
376_A	380_M	1.171	0.88
572_V	591_L	1.171	0.88
303_G	359_M	1.170	0.88
133_E	261_N	1.162	0.88
496_H	499_S	1.156	0.87
321_G	324_W	1.155	0.87
384_M	435_R	1.155	0.87
213_I	217_A	1.153	0.87
320_H	323_Q	1.145	0.87
49_D	164_D	1.141	0.87
105_T	117_V	1.141	0.87
135_D	138_S	1.140	0.87
250_Q	254_A	1.137	0.86
304_G	311_D	1.137	0.86
308_P	312_V	1.137	0.86
131_R	261_N	1.134	0.86
597_I	600_E	1.125	0.86
312_V	315_V	1.123	0.86
407_S	513_L	1.119	0.86
288_F	459_Y	1.119	0.86
295_M	363_F	1.115	0.85
366_F	500_L	1.113	0.85
431_S	466_A	1.110	0.85
22_Q	153_G	1.108	0.85
96_S	149_V	1.108	0.85
45_F	52_V	1.107	0.85
458_L	592_Y	1.106	0.85
208_M	216_R	1.106	0.85
93_V	301_N	1.096	0.84
522_V	526_L	1.092	0.84
365_S	503_Q	1.091	0.84
530_N	547_L	1.090	0.84
579_M	583_V	1.087	0.84
400_G	427_A	1.087	0.84
297_L	452_A	1.086	0.84
155_G	158_A	1.086	0.84
525_F	529_F	1.083	0.84
120_N	150_S	1.083	0.84
181_L	184_E	1.082	0.84
345_G	590_T	1.080	0.83
103_Y	245_A	1.079	0.83
314_S	318_F	1.078	0.83
323_Q	340_A	1.077	0.83
88_L	163_I	1.074	0.83
554_I	571_T	1.074	0.83
555_T	567_N	1.072	0.83
135_D	280_N	1.071	0.83
296_F	384_M	1.069	0.83
306_L	309_L	1.063	0.82
543_N	548_A	1.061	0.82
233_L	237_M	1.061	0.82
330_H	336_T	1.060	0.82
284_G	379_V	1.060	0.82
416_A	419_E	1.057	0.82
33_W	443_A	1.055	0.82
64_T	73_D	1.052	0.82
428_P	466_A	1.052	0.82
78_C	207_Q	1.051	0.82
101_N	485_F	1.049	0.82
288_F	558_F	1.043	0.81
249_Y	252_I	1.042	0.81
144_P	162_A	1.041	0.81
91_N	108_L	1.036	0.81
289_L	456_F	1.036	0.81
19_L	159_L	1.036	0.81
122_L	148_L	1.036	0.81
193_P	201_R	1.035	0.81
255_I	259_V	1.034	0.81
380_M	415_D	1.031	0.80
95_A	122_L	1.030	0.80
5_T	84_G	1.030	0.80
66_I	207_Q	1.030	0.80
333_D	337_I	1.029	0.80
402_G	581_K	1.029	0.80
228_A	232_R	1.027	0.80
567_N	570_A	1.026	0.80
66_I	73_D	1.026	0.80
533_S	546_A	1.023	0.80
453_L	456_F	1.023	0.80
430_M	466_A	1.022	0.80
425_M	473_L	1.021	0.80
444_A	451_G	1.019	0.80
161_L	165_R	1.018	0.80
422_M	476_T	1.012	0.79
116_I	162_A	1.009	0.79
88_L	116_I	1.006	0.79
19_L	118_A	1.002	0.79
72_L	417_P	0.996	0.78
19_L	156_I	0.996	0.78
428_P	439_F	0.996	0.78
536_G	539_V	0.990	0.78
229_A	232_R	0.988	0.78
136_A	259_V	0.986	0.77
547_L	572_V	0.983	0.77
376_A	384_M	0.982	0.77
177_Y	182_L	0.981	0.77
121_M	493_H	0.976	0.77
209_L	240_P	0.972	0.76
533_S	548_A	0.969	0.76
221_E	224_Q	0.967	0.76
46_S	51_Q	0.967	0.76
404_N	435_R	0.965	0.76
105_T	109_L	0.962	0.76
281_R	378_F	0.962	0.76
296_F	299_A	0.959	0.75
93_V	105_T	0.957	0.75
442_F	583_V	0.954	0.75
177_Y	202_R	0.953	0.75
54_L	90_I	0.949	0.75
499_S	503_Q	0.942	0.74
94_D	107_Q	0.942	0.74
96_S	125_A	0.941	0.74
189_A	202_R	0.939	0.74
270_F	273_A	0.938	0.74
291_V	295_M	0.938	0.74
224_Q	228_A	0.937	0.74
330_H	333_D	0.935	0.74
7_G	86_A	0.932	0.73
187_S	232_R	0.930	0.73
441_V	444_A	0.926	0.73
214_Y	217_A	0.926	0.73
137_L	255_I	0.926	0.73
516_G	519_I	0.924	0.73
139_A	228_A	0.923	0.73
300_I	493_H	0.923	0.73
570_A	592_Y	0.923	0.73
421_L	478_M	0.920	0.72
551_S	571_T	0.920	0.72
105_T	143_C	0.919	0.72
29_R	40_R	0.917	0.72
72_L	75_Q	0.915	0.72
438_I	519_I	0.913	0.72
407_S	410_G	0.913	0.72
284_G	539_V	0.912	0.72
424_I	427_A	0.911	0.72
95_A	125_A	0.910	0.72
246_D	250_Q	0.910	0.72
326_G	331_F	0.909	0.71
307_Q	356_Q	0.908	0.71
89_L	108_L	0.908	0.71
360_M	437_A	0.907	0.71
365_S	369_D	0.905	0.71
401_F	463_I	0.903	0.71
89_L	114_P	0.903	0.71
225_H	229_A	0.903	0.71
206_L	244_I	0.902	0.71
118_A	148_L	0.899	0.71
303_G	307_Q	0.898	0.71
184_E	232_R	0.898	0.71
254_A	258_V	0.897	0.70
23_L	28_Q	0.895	0.70
111_L	200_Q	0.891	0.70
148_L	156_I	0.891	0.70
91_N	303_G	0.890	0.70
83_S	86_A	0.890	0.70
356_Q	361_Y	0.889	0.70
96_S	128_Q	0.889	0.70
309_L	313_G	0.887	0.70
307_Q	311_D	0.885	0.69
555_T	559_K	0.885	0.69
229_A	233_L	0.884	0.69
99_E	253_A	0.882	0.69
419_E	474_K	0.882	0.69
188_L	226_L	0.880	0.69
338_F	341_Q	0.878	0.69
187_S	193_P	0.871	0.68
522_V	579_M	0.868	0.68
288_F	395_V	0.866	0.68
352_P	435_R	0.864	0.68
428_P	431_S	0.862	0.67
408_V	411_A	0.858	0.67
359_M	363_F	0.857	0.67
7_G	80_Y	0.857	0.67
66_I	435_R	0.854	0.67
304_G	397_L	0.852	0.66
419_E	425_M	0.849	0.66
297_L	548_A	0.849	0.66
185_A	202_R	0.849	0.66
436_L	560_P	0.849	0.66
231_A	234_R	0.848	0.66
294_L	363_F	0.847	0.66
547_L	558_F	0.845	0.66
306_L	359_M	0.844	0.66
384_M	387_L	0.842	0.66
190_K	193_P	0.841	0.65
308_P	433_G	0.839	0.65
187_S	225_H	0.839	0.65
163_I	167_K	0.838	0.65
363_F	463_I	0.838	0.65
300_I	451_G	0.837	0.65
225_H	228_A	0.836	0.65
46_S	49_D	0.833	0.65
370_S	574_L	0.833	0.65
357_I	519_I	0.832	0.65
243_H	474_K	0.832	0.65
191_V	225_H	0.830	0.64
401_F	404_N	0.827	0.64
288_F	560_P	0.823	0.64
349_T	444_A	0.823	0.64
309_L	312_V	0.822	0.64
367_L	521_I	0.822	0.64
188_L	209_L	0.821	0.64
279_L	467_V	0.820	0.63
529_F	550_V	0.816	0.63
369_D	407_S	0.815	0.63
357_I	409_M	0.814	0.63
339_L	554_I	0.812	0.63
499_S	502_I	0.812	0.63
88_L	167_K	0.809	0.62
6_I	125_A	0.809	0.62
177_Y	181_L	0.808	0.62
459_Y	560_P	0.806	0.62
469_T	472_M	0.805	0.62
535_S	539_V	0.801	0.62
471_L	474_K	0.801	0.62
307_Q	414_L	0.800	0.62
354_V	358_G	0.799	0.61
408_V	570_A	0.799	0.61
138_S	162_A	0.798	0.61
121_M	369_D	0.796	0.61
192_M	196_I	0.795	0.61
362_L	497_V	0.795	0.61
397_L	427_A	0.794	0.61
319_V	345_G	0.793	0.61
110_E	248_R	0.792	0.61
4_L	88_L	0.791	0.61
439_F	466_A	0.790	0.61
17_T	30_V	0.789	0.60
106_L	252_I	0.787	0.60
9_I	110_E	0.787	0.60
230_L	291_V	0.786	0.60
109_L	143_C	0.785	0.60
535_S	540_D	0.785	0.60
462_G	466_A	0.784	0.60
44_Q	51_Q	0.783	0.60
397_L	526_L	0.782	0.60
89_L	113_I	0.780	0.60
202_R	209_L	0.779	0.59
436_L	459_Y	0.779	0.59
575_F	578_A	0.777	0.59
572_V	578_A	0.775	0.59
378_F	393_S	0.774	0.59
75_Q	78_C	0.773	0.59
596_N	600_E	0.771	0.59
211_G	230_L	0.770	0.59
369_D	499_S	0.769	0.58
110_E	244_I	0.769	0.58
322_I	330_H	0.767	0.58
140_R	254_A	0.766	0.58
112_G	115_C	0.765	0.58
183_N	190_K	0.764	0.58
299_A	577_G	0.764	0.58
14_S	305_A	0.761	0.58
118_A	155_G	0.760	0.58
402_G	447_F	0.759	0.57
451_G	456_F	0.758	0.57
24_T	361_Y	0.758	0.57
303_G	409_M	0.758	0.57
555_T	558_F	0.757	0.57
89_L	115_C	0.757	0.57
439_F	574_L	0.756	0.57
220_G	325_I	0.756	0.57
574_L	588_L	0.756	0.57
87_D	170_E	0.754	0.57
344_G	348_N	0.754	0.57
178_A	182_L	0.753	0.57
324_W	328_T	0.751	0.57
376_A	401_F	0.749	0.56
385_Q	390_P	0.749	0.56
95_A	369_D	0.747	0.56
20_F	369_D	0.746	0.56
505_W	509_K	0.746	0.56
322_I	325_I	0.744	0.56
33_W	470_G	0.743	0.56
249_Y	470_G	0.742	0.56
286_P	581_K	0.741	0.56
131_R	165_R	0.740	0.56
183_N	290_F	0.739	0.55
60_T	440_A	0.735	0.55
141_L	145_V	0.731	0.55
153_G	156_I	0.731	0.55
253_A	257_D	0.729	0.54
217_A	220_G	0.729	0.54
558_F	561_I	0.728	0.54
380_M	419_E	0.727	0.54
290_F	398_I	0.727	0.54
555_T	570_A	0.727	0.54
567_N	588_L	0.726	0.54
106_L	255_I	0.726	0.54
189_A	193_P	0.726	0.54
555_T	563_V	0.725	0.54
300_I	401_F	0.722	0.54
256_C	260_S	0.721	0.54
286_P	404_N	0.720	0.54
399_V	402_G	0.719	0.53
119_L	148_L	0.718	0.53
534_L	549_S	0.715	0.53
563_V	566_D	0.715	0.53
291_V	366_F	0.715	0.53
443_A	584_V	0.712	0.53
191_V	194_S	0.711	0.53
98_L	117_V	0.711	0.53
350_V	519_I	0.711	0.53
426_M	431_S	0.711	0.53
447_F	454_A	0.711	0.53
576_T	584_V	0.710	0.52
17_T	77_A	0.710	0.52
547_L	575_F	0.710	0.52
115_C	143_C	0.709	0.52
528_A	532_F	0.709	0.52
222_A	225_H	0.709	0.52
182_L	185_A	0.708	0.52
418_R	480_G	0.707	0.52
338_F	343_L	0.706	0.52
8_L	28_Q	0.706	0.52
517_K	520_I	0.705	0.52
460_M	525_F	0.703	0.52
101_N	462_G	0.703	0.52
26_S	581_K	0.703	0.52
411_A	427_A	0.703	0.52
511_F	555_T	0.702	0.52
182_L	186_D	0.702	0.52
131_R	263_L	0.700	0.51
116_I	159_L	0.699	0.51
288_F	292_M	0.699	0.51
18_T	151_T	0.699	0.51
249_Y	415_D	0.697	0.51
441_V	585_V	0.697	0.51
500_L	504_T	0.693	0.51
119_L	147_P	0.693	0.51
421_L	424_I	0.691	0.51
400_G	404_N	0.690	0.50
428_P	574_L	0.690	0.50
426_M	469_T	0.689	0.50
296_F	431_S	0.688	0.50
101_N	249_Y	0.686	0.50
288_F	462_G	0.684	0.50
73_D	376_A	0.684	0.50
536_G	546_A	0.683	0.50
414_L	424_I	0.682	0.50
390_P	533_S	0.682	0.50
168_A	281_R	0.680	0.49
534_L	546_A	0.680	0.49
158_A	161_L	0.679	0.49
452_A	526_L	0.679	0.49
584_V	588_L	0.679	0.49
422_M	478_M	0.678	0.49
185_A	282_F	0.675	0.49
306_L	319_V	0.675	0.49
358_G	513_L	0.675	0.49
215_S	226_L	0.675	0.49
181_L	247_A	0.675	0.49
20_F	409_M	0.671	0.48
370_S	428_P	0.670	0.48
397_L	476_T	0.670	0.48
226_L	230_L	0.669	0.48
578_A	588_L	0.669	0.48
264_T	494_V	0.667	0.48
443_A	573_G	0.667	0.48
296_F	435_R	0.667	0.48
278_V	283_L	0.664	0.48
370_S	436_L	0.661	0.47
72_L	378_F	0.661	0.47
17_T	387_L	0.661	0.47
494_V	500_L	0.660	0.47
33_W	569_Q	0.660	0.47
116_I	166_Y	0.660	0.47
347_I	520_I	0.660	0.47
208_M	219_A	0.660	0.47
9_I	77_A	0.659	0.47
402_G	577_G	0.659	0.47
461_L	465_M	0.658	0.47
319_V	344_G	0.658	0.47
359_M	362_L	0.658	0.47
426_M	470_G	0.657	0.47
404_N	581_K	0.656	0.47
346_G	353_L	0.656	0.47
387_L	435_R	0.656	0.47
78_C	210_E	0.656	0.47
89_L	111_L	0.655	0.47
398_I	419_E	0.654	0.47
356_Q	444_A	0.653	0.47
293_Y	456_F	0.652	0.47
324_W	327_Y	0.651	0.46
456_F	460_M	0.651	0.46
232_R	236_E	0.649	0.46
367_L	517_K	0.649	0.46
307_Q	438_I	0.649	0.46
161_L	450_N	0.648	0.46
153_G	518_V	0.646	0.46
6_I	160_K	0.646	0.46
301_N	458_L	0.646	0.46
507_R	510_G	0.646	0.46
279_L	379_V	0.646	0.46
535_S	538_I	0.645	0.46
459_Y	558_F	0.643	0.46
268_S	272_T	0.643	0.46
191_V	229_A	0.642	0.46
486_V	585_V	0.639	0.45
43_G	279_L	0.639	0.45
89_L	214_Y	0.639	0.45
302_I	373_M	0.638	0.45
269_R	273_A	0.638	0.45
222_A	229_A	0.638	0.45
310_F	401_F	0.638	0.45
164_D	167_K	0.638	0.45
380_M	397_L	0.637	0.45
295_M	376_A	0.635	0.45
216_R	226_L	0.634	0.45
334_W	397_L	0.633	0.45
352_P	431_S	0.633	0.45
329_L	339_L	0.632	0.44
506_Q	556_P	0.631	0.44
598_Q	601_E	0.631	0.44
303_G	373_M	0.631	0.44
254_A	385_Q	0.631	0.44
79_H	274_V	0.630	0.44
269_R	501_I	0.630	0.44
164_D	168_A	0.629	0.44
207_Q	435_R	0.629	0.44
338_F	524_I	0.629	0.44
85_D	113_I	0.628	0.44
439_F	443_A	0.627	0.44
498_K	503_Q	0.627	0.44
320_H	366_F	0.627	0.44
286_P	577_G	0.626	0.44
288_F	431_S	0.623	0.44
230_L	234_R	0.623	0.44
527_S	579_M	0.622	0.43
201_R	205_G	0.621	0.43
66_I	212_D	0.621	0.43
345_G	523_S	0.621	0.43
544_D	549_S	0.619	0.43
17_T	36_V	0.619	0.43
62_S	86_A	0.619	0.43
274_V	479_R	0.619	0.43
130_I	263_L	0.618	0.43
23_L	43_G	0.617	0.43
476_T	480_G	0.617	0.43
551_S	579_M	0.617	0.43
542_I	590_T	0.616	0.43
530_N	542_I	0.616	0.43
430_M	583_V	0.615	0.43
65_T	474_K	0.615	0.43
352_P	385_Q	0.615	0.43
356_Q	359_M	0.614	0.43
121_M	487_M	0.614	0.43
183_N	186_D	0.611	0.42
299_A	363_F	0.610	0.42
467_V	572_V	0.610	0.42
316_A	321_G	0.608	0.42
533_S	549_S	0.608	0.42
326_G	329_L	0.607	0.42
17_T	33_W	0.607	0.42
177_Y	206_L	0.607	0.42
366_F	497_V	0.606	0.42
203_W	363_F	0.605	0.42
17_T	41_K	0.605	0.42
502_I	508_L	0.604	0.42
44_Q	53_T	0.602	0.41
555_T	566_D	0.602	0.41
442_F	458_L	0.602	0.41
318_F	339_L	0.601	0.41
439_F	458_L	0.601	0.41
360_M	441_V	0.600	0.41
596_N	599_D	0.600	0.41
347_I	517_K	0.598	0.41
83_S	218_Y	0.597	0.41
31_G	413_T	0.597	0.41
445_A	576_T	0.597	0.41
149_V	390_P	0.596	0.41
303_G	484_P	0.596	0.41
53_T	253_A	0.595	0.41
418_R	467_V	0.593	0.41
125_A	149_V	0.593	0.41
203_W	207_Q	0.592	0.40
299_A	402_G	0.592	0.40
75_Q	79_H	0.591	0.40
145_V	386_A	0.591	0.40
222_A	228_A	0.590	0.40
28_Q	41_K	0.590	0.40
549_S	552_R	0.590	0.40
54_L	397_L	0.589	0.40
323_Q	341_Q	0.588	0.40
576_T	591_L	0.586	0.40
103_Y	210_E	0.585	0.40
397_L	439_F	0.585	0.40
536_G	548_A	0.584	0.40
416_A	470_G	0.584	0.40
30_V	455_V	0.582	0.40
400_G	459_Y	0.581	0.39
63_L	87_D	0.581	0.39
300_I	470_G	0.580	0.39
28_Q	531_S	0.580	0.39
351_L	405_V	0.580	0.39
73_D	77_A	0.579	0.39
401_F	407_S	0.579	0.39
354_V	533_S	0.578	0.39
278_V	313_G	0.578	0.39
5_T	80_Y	0.578	0.39
353_L	519_I	0.577	0.39
298_L	588_L	0.576	0.39
114_P	370_S	0.576	0.39
186_D	225_H	0.576	0.39
19_L	502_I	0.576	0.39
39_E	116_I	0.576	0.39
44_Q	54_L	0.575	0.39
244_I	402_G	0.575	0.39
347_I	350_V	0.575	0.39
377_A	480_G	0.574	0.39
23_L	160_K	0.573	0.39
235_N	273_A	0.573	0.39
204_L	215_S	0.573	0.39
503_Q	514_R	0.572	0.39
438_I	441_V	0.571	0.38
384_M	404_N	0.570	0.38
331_F	336_T	0.570	0.38
255_I	258_V	0.570	0.38
64_T	210_E	0.568	0.38
417_P	425_M	0.567	0.38
408_V	551_S	0.567	0.38
435_R	546_A	0.566	0.38
520_I	540_D	0.566	0.38
184_E	187_S	0.566	0.38
35_G	368_E	0.565	0.38
349_T	352_P	0.564	0.38
149_V	154_R	0.564	0.38
530_N	573_G	0.563	0.38
180_P	187_S	0.562	0.38
75_Q	206_L	0.562	0.38
81_I	387_L	0.562	0.38
4_L	52_V	0.562	0.38
26_S	514_R	0.562	0.38
300_I	407_S	0.562	0.38
548_A	563_V	0.562	0.38
539_V	585_V	0.562	0.38
419_E	515_A	0.562	0.38
530_N	591_L	0.561	0.37
296_F	352_P	0.559	0.37
212_D	246_D	0.558	0.37
185_A	205_G	0.558	0.37
422_M	426_M	0.558	0.37
303_G	396_P	0.557	0.37
296_F	300_I	0.556	0.37
156_I	160_K	0.556	0.37
271_T	279_L	0.556	0.37
179_Q	186_D	0.555	0.37
90_I	166_Y	0.554	0.37
128_Q	269_R	0.554	0.37
81_I	210_E	0.554	0.37
115_C	494_V	0.553	0.37
176_H	179_Q	0.553	0.37
149_V	153_G	0.553	0.37
337_I	527_S	0.553	0.37
393_S	455_V	0.553	0.37
97_N	485_F	0.552	0.37
460_M	464_V	0.552	0.37
278_V	379_V	0.552	0.37
60_T	421_L	0.552	0.37
71_S	125_A	0.552	0.37
230_L	233_L	0.551	0.37
90_I	160_K	0.551	0.37
281_R	493_H	0.551	0.37
98_L	185_A	0.551	0.37
36_V	430_M	0.551	0.37
209_L	233_L	0.550	0.36
176_H	182_L	0.550	0.36
65_T	114_P	0.549	0.36
93_V	98_L	0.549	0.36
299_A	359_M	0.548	0.36
344_G	438_I	0.548	0.36
362_L	500_L	0.547	0.36
433_G	511_F	0.547	0.36
304_G	438_I	0.547	0.36
359_M	523_S	0.547	0.36
348_N	590_T	0.547	0.36
203_W	493_H	0.546	0.36
422_M	474_K	0.546	0.36
327_Y	340_A	0.546	0.36
157_E	179_Q	0.545	0.36
361_Y	364_L	0.544	0.36
107_Q	248_R	0.543	0.36
293_Y	297_L	0.543	0.36
360_M	378_F	0.542	0.36
96_S	430_M	0.542	0.36
24_T	409_M	0.541	0.36
452_A	576_T	0.540	0.35
529_F	546_A	0.540	0.35
131_R	277_I	0.540	0.35
109_L	298_L	0.540	0.35
312_V	316_A	0.539	0.35
113_I	512_V	0.538	0.35
397_L	519_I	0.538	0.35
79_H	218_Y	0.538	0.35
469_T	561_I	0.537	0.35
430_M	439_F	0.537	0.35
270_F	278_V	0.537	0.35
266_E	543_N	0.536	0.35
385_Q	590_T	0.536	0.35
215_S	219_A	0.534	0.35
215_S	218_Y	0.534	0.35
71_S	120_N	0.533	0.35
156_I	159_L	0.533	0.35
416_A	483_T	0.533	0.35
33_W	334_W	0.533	0.35
349_T	523_S	0.532	0.35
468_L	471_L	0.531	0.35
301_N	304_G	0.531	0.35
384_M	556_P	0.531	0.35
90_I	116_I	0.530	0.35
298_L	452_A	0.528	0.34
334_W	531_S	0.528	0.34
429_F	577_G	0.528	0.34
526_L	583_V	0.527	0.34
287_I	366_F	0.526	0.34
114_P	396_P	0.526	0.34
384_M	426_M	0.525	0.34
110_E	177_Y	0.524	0.34
72_L	420_R	0.524	0.34
513_L	517_K	0.524	0.34
92_V	119_L	0.523	0.34
201_R	215_S	0.523	0.34
451_G	573_G	0.522	0.34
345_G	478_M	0.522	0.34
65_T	248_R	0.522	0.34
211_G	240_P	0.522	0.34
349_T	527_S	0.521	0.34
555_T	579_M	0.521	0.34
299_A	356_Q	0.520	0.34
441_V	445_A	0.520	0.34
350_V	523_S	0.519	0.34
342_G	346_G	0.519	0.34
300_I	456_F	0.519	0.34
125_A	592_Y	0.518	0.33
499_S	507_R	0.518	0.33
522_V	583_V	0.517	0.33
16_K	35_G	0.517	0.33
347_I	447_F	0.516	0.33
586_G	590_T	0.515	0.33
365_S	504_T	0.515	0.33
221_E	225_H	0.514	0.33
130_I	379_V	0.514	0.33
473_L	501_I	0.514	0.33
384_M	439_F	0.514	0.33
379_V	386_A	0.513	0.33
19_L	147_P	0.513	0.33
362_L	413_T	0.512	0.33
318_F	322_I	0.512	0.33
217_A	231_A	0.512	0.33
192_M	201_R	0.511	0.33
363_F	511_F	0.511	0.33
522_V	586_G	0.510	0.33
535_S	543_N	0.509	0.33
410_G	470_G	0.509	0.33
52_V	243_H	0.508	0.33
7_G	274_V	0.508	0.33
103_Y	248_R	0.507	0.32
130_I	262_T	0.506	0.32
305_A	576_T	0.506	0.32
384_M	574_L	0.506	0.32
310_F	348_N	0.505	0.32
25_G	467_V	0.505	0.32
226_L	233_L	0.505	0.32
502_I	505_W	0.505	0.32
242_L	485_F	0.505	0.32
287_I	290_F	0.504	0.32
60_T	77_A	0.503	0.32
519_I	523_S	0.503	0.32
98_L	102_L	0.503	0.32
148_L	390_P	0.502	0.32
340_A	458_L	0.502	0.32
393_S	422_M	0.502	0.32
365_S	509_K	0.501	0.32
43_G	424_I	0.501	0.32
431_S	574_L	0.501	0.32
329_L	460_M	0.501	0.32
412_R	442_F	0.501	0.32
425_M	428_P	0.501	0.32
366_F	496_H	0.500	0.32
101_N	287_I	0.500	0.32
457_S	588_L	0.500	0.32

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3ibyA	1	0.3234	100	0.81	Contact Map
3i8sA	1	0.3415	100	0.814	Contact Map
3k53A	2	0.3351	100	0.816	Contact Map
3b1vA	1	0.3325	100	0.817	Contact Map
3a1sA	1	0.3247	100	0.817	Contact Map
2j69A	1	0.533	100	0.892	Contact Map
2wjgA	1	0.2147	100	0.892	Contact Map
1mkyA	1	0.3014	100	0.898	Contact Map
2wjiA	1	0.207	100	0.898	Contact Map
3geeA	2	0.2497	100	0.901	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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