NUOL - ECOLI - GREMLIN Contacts

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NUOL - NADH-quinone oxidoreductase subunit L

UniProt:	P33607	Sequences: MNMLALTIILPLIGFVLLAFSRGRWSENVSAIVGVGSVGLAALVTAFIGVDFFANGEQTYSQPLWTWMSVGDFNIGFNLVLDGLSLTMLSVVTGVGFLIHMYASWYMRGEEGYSRFFAYTNLFIASMVVLVLADNLLLMYLGWEGVGLCSYLLIGFYYTDPKNGAAAMKAFVVTRVGDVFLAFALFILYNELGTLNFREMVELAPAHFADGNNMLMWATLMLLGGAVGKSAQLPLQTWLADAMAGPTPVSALIHAATMVTAGVYLIARTHGLFLMTPEVLHLVGIVGAVTLLLAGFAALVQTDIKRVLAYSTMSQIGYMFLALGVQAWDAAIFHLMTHAFFKALLFLASGSVILACHHEQNIFKMGGLRKSIPLVYLCFLVGGAALSALPLVTAGFFSKDEILAGAMANGHINLMVAGLVGAFMTSLYTFRMIFIVFHGKEQIHAHAVKGVTHSLPLIVLLILSTFVGALIVPPLQGVLPQTTELAHGSMLTLEITSGVVAVVGILLAAWLWLGKRTLVTSIANSAPGRLLGTWWYNAWGFDWLYDKVFVKPFLGIAWLLKRDPLNSMMNIPAVLSRFAGKGLLLSENGYLRWYVASMSIGAVVVLALLMVLR	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG12092
Length:	613 (479)
Sequences:	14886 (8650)
Seq/√Len:	395.2

ECOLI - NUOL HYFB HYCC HYFD NUOM HYFF NUON
BACSU - MRPA MRPD NDHF
HALSA - Q9HRL3 Q9HRT0 Q9HRS9 Q9HRL2 Q9HRL1 Q9HRS8
SULSO - Q97ZA9 Q980G9 Q980G8 Q97ZA6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
129_V	142_G	4.605	1.00
82_D	268_R	4.326	1.00
196_N	199_E	4.219	1.00
89_L	132_L	3.603	1.00
344_L	382_G	3.522	1.00
14_G	37_S	3.415	1.00
337_T	394_A	3.296	1.00
194_T	199_E	3.236	1.00
39_G	97_F	2.961	1.00
155_G	167_A	2.943	1.00
302_T	363_F	2.906	1.00
96_G	124_I	2.879	1.00
359_E	364_K	2.844	1.00
303_D	360_Q	2.818	1.00
169_K	241_D	2.811	1.00
380_L	433_I	2.698	1.00
42_A	94_G	2.625	1.00
12_L	125_A	2.605	1.00
287_G	324_G	2.580	1.00
334_H	398_S	2.568	1.00
307_V	362_I	2.535	1.00
89_L	128_V	2.445	1.00
361_N	364_K	2.441	1.00
103_A	116_F	2.407	1.00
383_G	429_T	2.377	1.00
92_V	131_V	2.373	1.00
295_G	314_S	2.310	1.00
184_A	221_M	2.308	1.00
321_L	418_G	2.176	1.00
291_L	421_G	2.134	1.00
451_V	455_L	2.125	1.00
308_L	349_S	2.113	1.00
243_M	259_V	2.076	1.00
136_L	269_T	2.050	1.00
93_T	128_V	2.041	1.00
299_L	427_L	2.032	1.00
259_V	312_T	2.016	1.00
91_V	339_A	2.016	1.00
311_S	428_Y	2.015	1.00
232_Q	320_F	1.982	1.00
233_L	289_V	1.981	1.00
243_M	250_S	1.939	1.00
375_V	448_V	1.916	1.00
136_L	200_M	1.916	1.00
133_A	138_L	1.915	1.00
288_A	417_A	1.889	1.00
267_A	323_L	1.886	1.00
362_I	436_V	1.861	1.00
379_F	432_M	1.859	1.00
333_F	398_S	1.851	1.00
223_L	227_V	1.850	1.00
87_T	336_M	1.849	1.00
187_I	218_A	1.839	1.00
39_G	43_L	1.836	1.00
281_H	285_I	1.825	1.00
325_V	406_A	1.815	1.00
223_L	283_V	1.803	1.00
372_I	375_V	1.790	1.00
191_E	218_A	1.790	1.00
78_N	134_D	1.776	1.00
462_I	466_F	1.776	1.00
283_V	324_G	1.769	1.00
304_I	432_M	1.765	1.00
45_T	93_T	1.757	1.00
284_G	324_G	1.752	1.00
369_R	376_Y	1.734	1.00
403_L	418_G	1.732	1.00
323_L	331_A	1.727	1.00
302_T	361_N	1.721	1.00
42_A	46_A	1.721	1.00
43_L	47_F	1.717	1.00
376_Y	438_H	1.709	1.00
85_S	264_Y	1.705	1.00
126_S	145_G	1.685	1.00
66_T	76_G	1.669	1.00
213_N	217_W	1.663	1.00
431_R	435_I	1.657	1.00
376_Y	433_I	1.648	1.00
112_G	115_R	1.634	1.00
162_K	244_A	1.632	1.00
8_I	11_P	1.631	1.00
379_F	383_G	1.611	1.00
81_L	132_L	1.609	1.00
199_E	203_L	1.607	1.00
134_D	198_R	1.603	1.00
38_V	42_A	1.599	1.00
199_E	202_E	1.599	1.00
381_V	461_L	1.593	1.00
49_G	53_F	1.583	1.00
412_I	416_V	1.580	1.00
46_A	50_V	1.578	1.00
330_A	405_G	1.571	1.00
267_A	331_A	1.567	1.00
340_F	463_L	1.566	1.00
166_A	244_A	1.559	1.00
100_H	120_T	1.542	1.00
42_A	93_T	1.533	1.00
173_V	237_T	1.521	1.00
80_V	134_D	1.521	1.00
184_A	225_G	1.511	1.00
26_S	29_V	1.470	1.00
284_G	414_L	1.467	1.00
378_C	461_L	1.466	1.00
470_L	473_P	1.459	1.00
301_Q	306_R	1.459	1.00
192_L	200_M	1.455	1.00
266_I	320_F	1.432	1.00
64_L	76_G	1.427	1.00
227_V	232_Q	1.425	1.00
29_V	32_I	1.422	1.00
139_M	265_L	1.421	1.00
278_E	281_H	1.418	1.00
27_E	31_A	1.410	1.00
404_A	408_A	1.406	1.00
66_T	69_S	1.395	1.00
322_A	402_I	1.392	1.00
80_V	83_G	1.369	1.00
491_L	495_I	1.358	1.00
456_P	459_V	1.355	1.00
105_W	452_T	1.355	1.00
406_A	415_M	1.351	1.00
194_T	200_M	1.348	1.00
15_F	19_A	1.347	1.00
153_L	249_V	1.345	1.00
450_G	453_H	1.343	1.00
264_Y	268_R	1.337	1.00
451_V	454_S	1.333	1.00
287_G	321_L	1.333	1.00
472_V	476_Q	1.331	1.00
135_N	196_N	1.329	1.00
97_F	101_M	1.327	1.00
226_A	265_L	1.320	1.00
383_G	433_I	1.317	1.00
8_I	125_A	1.317	1.00
98_L	459_V	1.313	1.00
384_A	389_L	1.307	1.00
232_Q	286_V	1.299	1.00
75_I	137_L	1.295	1.00
197_F	201_V	1.293	1.00
227_V	286_V	1.285	1.00
95_V	343_A	1.280	1.00
285_I	289_V	1.278	1.00
374_L	458_I	1.277	1.00
82_D	85_S	1.274	1.00
327_A	405_G	1.266	1.00
416_V	420_V	1.265	1.00
287_G	317_G	1.263	1.00
189_Y	195_L	1.261	1.00
161_P	165_A	1.258	1.00
220_L	224_G	1.257	1.00
184_A	218_A	1.252	1.00
186_F	190_N	1.250	1.00
130_L	261_A	1.244	1.00
137_L	195_L	1.241	1.00
119_Y	152_L	1.241	1.00
10_L	37_S	1.235	1.00
476_Q	479_L	1.232	1.00
292_L	421_G	1.228	1.00
49_G	90_S	1.228	1.00
353_I	360_Q	1.223	1.00
95_V	256_A	1.213	1.00
187_I	214_M	1.211	1.00
36_G	40_L	1.211	1.00
386_L	429_T	1.202	1.00
295_G	421_G	1.201	1.00
314_S	425_T	1.197	1.00
45_T	89_L	1.187	1.00
228_G	235_L	1.184	1.00
378_C	458_I	1.183	1.00
413_N	416_V	1.182	1.00
459_V	463_L	1.182	1.00
15_F	18_L	1.176	1.00
479_L	483_T	1.176	1.00
163_N	244_A	1.175	1.00
41_A	45_T	1.172	1.00
98_L	456_P	1.168	1.00
288_A	414_L	1.157	1.00
319_M	331_A	1.152	1.00
348_A	379_F	1.146	1.00
28_N	32_I	1.145	1.00
180_F	224_G	1.142	1.00
189_Y	192_L	1.139	1.00
7_T	44_V	1.135	1.00
46_A	90_S	1.135	1.00
88_M	335_L	1.134	1.00
355_A	372_I	1.130	1.00
354_L	447_A	1.128	1.00
329_D	479_L	1.124	1.00
50_V	54_A	1.123	1.00
263_V	320_F	1.121	1.00
315_Q	425_T	1.119	1.00
180_F	221_M	1.118	1.00
378_C	457_L	1.117	1.00
15_F	118_A	1.115	1.00
8_I	79_L	1.112	1.00
216_M	278_E	1.110	1.00
84_L	332_I	1.108	1.00
341_F	385_A	1.106	1.00
219_T	279_V	1.104	1.00
379_F	437_F	1.102	1.00
38_V	100_H	1.100	1.00
217_W	221_M	1.099	1.00
280_L	284_G	1.097	1.00
473_P	476_Q	1.095	1.00
41_A	48_I	1.089	1.00
490_M	493_L	1.087	1.00
377_L	381_V	1.086	1.00
337_T	398_S	1.083	1.00
120_T	252_L	1.082	1.00
201_V	271_G	1.080	1.00
284_G	321_L	1.079	1.00
466_F	470_L	1.078	1.00
490_M	494_E	1.073	1.00
218_A	222_L	1.072	1.00
93_T	97_F	1.070	1.00
287_G	320_F	1.070	1.00
30_S	34_G	1.069	1.00
338_H	342_K	1.066	1.00
344_L	460_L	1.065	1.00
90_S	94_G	1.060	1.00
87_T	332_I	1.059	1.00
6_L	10_L	1.058	1.00
251_A	347_L	1.056	1.00
38_V	41_A	1.052	1.00
19_A	22_R	1.051	1.00
78_N	196_N	1.051	1.00
351_S	449_K	1.045	1.00
394_A	467_V	1.044	1.00
102_Y	347_L	1.043	1.00
458_I	462_I	1.043	1.00
366_G	442_Q	1.041	1.00
35_V	101_M	1.040	1.00
362_I	435_I	1.040	1.00
140_Y	182_A	1.038	1.00
40_L	44_V	1.035	1.00
69_S	72_D	1.033	1.00
394_A	464_S	1.030	1.00
195_L	199_E	1.028	1.00
105_W	450_G	1.027	1.00
91_V	336_M	1.027	1.00
37_S	41_A	1.026	1.00
233_L	293_L	1.023	1.00
10_L	40_L	1.022	1.00
32_I	36_G	1.021	1.00
5_A	8_I	1.021	1.00
452_T	456_P	1.019	1.00
62_Q	78_N	1.017	1.00
351_S	457_L	1.012	1.00
289_V	293_L	1.008	1.00
5_A	63_P	1.007	1.00
24_R	28_N	1.006	1.00
433_I	438_H	1.005	1.00
63_P	66_T	1.003	1.00
241_D	306_R	0.998	1.00
99_I	347_L	0.993	1.00
293_L	297_A	0.991	1.00
463_L	467_V	0.989	1.00
372_I	448_V	0.984	1.00
407_M	415_M	0.984	1.00
150_S	258_M	0.984	1.00
94_G	98_L	0.983	1.00
374_L	378_C	0.983	1.00
198_R	202_E	0.982	1.00
146_V	258_M	0.978	1.00
191_E	214_M	0.978	1.00
52_F	86_L	0.976	1.00
216_M	279_V	0.975	1.00
194_T	197_F	0.972	1.00
79_L	132_L	0.970	1.00
294_A	317_G	0.970	1.00
34_G	117_F	0.969	1.00
461_L	464_S	0.966	1.00
33_V	37_S	0.965	1.00
102_Y	350_G	0.962	1.00
81_L	86_L	0.961	1.00
84_L	267_A	0.956	1.00
47_F	51_D	0.954	1.00
159_T	163_N	0.953	1.00
356_C	365_M	0.952	1.00
401_E	404_A	0.951	1.00
344_L	457_L	0.951	1.00
351_S	375_V	0.951	1.00
315_Q	428_Y	0.945	1.00
123_F	127_M	0.943	1.00
348_A	457_L	0.941	1.00
480_P	483_T	0.934	1.00
478_V	481_Q	0.934	1.00
162_K	165_A	0.934	1.00
94_G	463_L	0.933	1.00
135_N	138_L	0.932	1.00
8_I	22_R	0.931	1.00
105_W	108_R	0.930	1.00
122_L	149_C	0.930	1.00
485_L	488_G	0.930	1.00
47_F	50_V	0.929	1.00
50_V	53_F	0.929	1.00
381_V	465_T	0.926	1.00
295_G	311_S	0.924	1.00
51_D	54_A	0.923	1.00
136_L	185_L	0.922	1.00
371_S	444_H	0.918	1.00
41_A	93_T	0.917	1.00
421_G	424_M	0.915	1.00
341_F	395_G	0.915	1.00
269_T	272_L	0.914	1.00
134_D	196_N	0.914	1.00
216_M	220_L	0.913	1.00
212_N	216_M	0.911	1.00
104_S	452_T	0.911	1.00
455_L	459_V	0.908	1.00
28_N	31_A	0.907	1.00
85_S	89_L	0.905	1.00
489_S	493_L	0.904	1.00
334_H	341_F	0.904	1.00
146_V	261_A	0.901	1.00
61_S	64_L	0.900	1.00
45_T	90_S	0.899	1.00
211_G	214_M	0.895	1.00
44_V	48_I	0.895	1.00
284_G	288_A	0.894	1.00
382_G	461_L	0.893	1.00
295_G	428_Y	0.891	1.00
217_W	220_L	0.891	1.00
430_F	434_F	0.890	1.00
188_L	200_M	0.889	1.00
53_F	56_G	0.888	1.00
322_A	327_A	0.887	1.00
296_F	424_M	0.887	1.00
68_M	75_I	0.884	1.00
374_L	454_S	0.883	1.00
291_L	321_L	0.880	1.00
312_T	338_H	0.877	1.00
184_A	222_L	0.876	1.00
45_T	48_I	0.874	1.00
154_I	242_A	0.873	1.00
266_I	273_F	0.873	1.00
231_A	239_L	0.872	1.00
291_L	318_Y	0.872	1.00
121_N	125_A	0.870	1.00
403_L	415_M	0.868	1.00
27_E	30_S	0.868	1.00
90_S	93_T	0.866	1.00
356_C	359_E	0.866	1.00
164_G	167_A	0.864	1.00
140_Y	185_L	0.860	1.00
85_S	268_R	0.856	1.00
66_T	74_N	0.856	1.00
403_L	422_A	0.851	1.00
22_R	114_S	0.849	1.00
352_V	368_L	0.848	1.00
49_G	86_L	0.847	1.00
165_A	169_K	0.846	1.00
348_A	378_C	0.845	1.00
484_E	488_G	0.837	1.00
322_A	331_A	0.836	1.00
489_S	494_E	0.835	1.00
4_L	81_L	0.832	1.00
391_L	469_A	0.831	1.00
383_G	387_S	0.831	1.00
52_F	60_Y	0.828	1.00
185_L	222_L	0.828	1.00
332_I	478_V	0.823	1.00
282_L	285_I	0.823	1.00
69_S	74_N	0.822	1.00
245_G	250_S	0.820	1.00
380_L	437_F	0.818	1.00
14_G	121_N	0.817	1.00
15_F	122_L	0.813	1.00
451_V	456_P	0.813	1.00
110_E	157_Y	0.812	1.00
101_M	455_L	0.811	1.00
139_M	197_F	0.810	1.00
123_F	258_M	0.809	1.00
187_I	191_E	0.807	1.00
26_S	30_S	0.807	1.00
377_L	380_L	0.807	1.00
239_L	243_M	0.802	1.00
467_V	474_P	0.801	1.00
493_L	496_T	0.799	1.00
288_A	321_L	0.799	1.00
303_D	361_N	0.798	1.00
126_S	149_C	0.798	1.00
454_S	458_I	0.793	1.00
127_M	258_M	0.793	1.00
212_N	215_L	0.792	1.00
278_E	282_L	0.789	1.00
114_S	118_A	0.786	1.00
304_I	436_V	0.785	1.00
400_D	404_A	0.784	1.00
271_G	274_L	0.784	1.00
42_A	49_G	0.783	1.00
455_L	458_I	0.782	1.00
307_V	432_M	0.781	1.00
371_S	441_E	0.777	1.00
35_V	97_F	0.777	1.00
260_T	264_Y	0.777	1.00
292_L	296_F	0.777	1.00
263_V	316_I	0.777	1.00
311_S	338_H	0.775	1.00
318_Y	418_G	0.774	1.00
239_L	242_A	0.773	1.00
95_V	339_A	0.772	1.00
366_G	439_G	0.767	1.00
86_L	90_S	0.764	1.00
35_V	39_G	0.763	1.00
42_A	97_F	0.761	1.00
380_L	438_H	0.759	1.00
116_F	248_P	0.759	1.00
368_L	372_I	0.759	1.00
374_L	377_L	0.758	1.00
449_K	454_S	0.757	1.00
177_G	228_G	0.757	1.00
92_V	128_V	0.757	1.00
37_S	121_N	0.755	1.00
376_Y	380_L	0.755	1.00
370_K	373_P	0.750	1.00
5_A	77_F	0.749	1.00
219_T	272_L	0.749	1.00
128_V	132_L	0.748	1.00
223_L	279_V	0.748	1.00
318_Y	421_G	0.748	1.00
489_S	492_T	0.747	1.00
314_S	428_Y	0.745	1.00
483_T	487_H	0.745	1.00
378_C	454_S	0.745	1.00
38_V	124_I	0.743	1.00
298_A	428_Y	0.742	1.00
24_R	27_E	0.740	1.00
143_W	261_A	0.740	1.00
304_I	352_V	0.740	1.00
277_P	280_L	0.739	1.00
239_L	259_V	0.738	1.00
243_M	312_T	0.738	1.00
200_M	203_L	0.738	1.00
223_L	266_I	0.738	1.00
48_I	52_F	0.738	1.00
10_L	14_G	0.737	1.00
480_P	484_E	0.737	1.00
31_A	35_V	0.733	1.00
433_I	437_F	0.729	1.00
64_L	78_N	0.727	1.00
219_T	273_F	0.723	1.00
304_I	349_S	0.722	1.00
175_R	178_D	0.721	1.00
48_I	61_S	0.721	1.00
255_A	338_H	0.719	1.00
188_L	218_A	0.719	1.00
213_N	216_M	0.718	1.00
10_L	44_V	0.717	1.00
188_L	222_L	0.716	1.00
359_E	365_M	0.715	1.00
315_Q	334_H	0.712	1.00
51_D	55_N	0.710	1.00
214_M	217_W	0.709	1.00
233_L	294_A	0.709	1.00
78_N	135_N	0.709	1.00
491_L	494_E	0.708	1.00
14_G	18_L	0.706	1.00
183_F	221_M	0.706	1.00
136_L	188_L	0.704	1.00
425_T	428_Y	0.703	1.00
30_S	33_V	0.702	1.00
315_Q	342_K	0.701	1.00
311_S	342_K	0.698	1.00
367_G	439_G	0.697	1.00
135_N	195_L	0.697	1.00
34_G	38_V	0.696	1.00
439_G	442_Q	0.696	1.00
18_L	22_R	0.694	1.00
34_G	100_H	0.694	1.00
473_P	477_G	0.694	1.00
53_F	60_Y	0.693	1.00
22_R	26_S	0.693	1.00
113_Y	117_F	0.692	1.00
192_L	203_L	0.690	1.00
45_T	49_G	0.689	1.00
376_Y	437_F	0.689	1.00
98_L	460_L	0.689	1.00
429_T	432_M	0.687	0.99
311_S	431_R	0.686	0.99
448_V	454_S	0.686	0.99
31_A	34_G	0.686	0.99
103_A	106_Y	0.685	0.99
340_F	394_A	0.685	0.99
19_A	118_A	0.684	0.99
4_L	79_L	0.682	0.99
96_G	120_T	0.681	0.99
367_G	441_E	0.681	0.99
371_S	446_H	0.680	0.99
41_A	44_V	0.679	0.99
302_T	311_S	0.677	0.99
15_F	125_A	0.676	0.99
245_G	305_K	0.676	0.99
182_A	186_F	0.675	0.99
181_L	185_L	0.675	0.99
476_Q	480_P	0.673	0.99
220_L	279_V	0.671	0.99
344_L	464_S	0.671	0.99
168_M	172_V	0.669	0.99
35_V	104_S	0.667	0.99
292_L	417_A	0.665	0.99
380_L	383_G	0.664	0.99
345_L	382_G	0.663	0.99
372_I	446_H	0.663	0.99
99_I	251_A	0.662	0.99
249_V	252_L	0.662	0.99
333_F	337_T	0.660	0.99
247_T	305_K	0.658	0.99
276_T	279_V	0.658	0.99
185_L	195_L	0.658	0.99
465_T	469_A	0.656	0.99
353_I	365_M	0.655	0.99
285_I	288_A	0.655	0.99
284_G	287_G	0.653	0.99
365_M	436_V	0.649	0.99
388_A	395_G	0.649	0.99
11_P	15_F	0.648	0.99
297_A	310_Y	0.648	0.99
102_Y	106_Y	0.646	0.99
106_Y	248_P	0.646	0.99
246_P	305_K	0.645	0.99
13_I	17_L	0.643	0.99
230_S	263_V	0.642	0.99
26_S	31_A	0.642	0.99
417_A	421_G	0.641	0.99
381_V	385_A	0.641	0.99
62_Q	65_W	0.639	0.99
295_G	425_T	0.638	0.99
341_F	464_S	0.637	0.99
23_G	27_E	0.637	0.99
281_H	284_G	0.636	0.99
385_A	395_G	0.635	0.99
187_I	217_W	0.633	0.99
223_L	282_L	0.633	0.99
35_V	38_V	0.632	0.99
424_M	428_Y	0.631	0.99
354_L	453_H	0.631	0.99
330_A	401_E	0.630	0.99
362_I	365_M	0.630	0.99
355_A	449_K	0.629	0.99
274_L	328_W	0.629	0.99
52_F	56_G	0.629	0.99
221_M	225_G	0.629	0.99
259_V	264_Y	0.629	0.99
222_L	226_A	0.629	0.99
99_I	120_T	0.628	0.99
127_M	257_T	0.627	0.99
181_L	265_L	0.627	0.99
100_H	117_F	0.626	0.99
215_L	218_A	0.626	0.99
420_V	424_M	0.624	0.99
315_Q	318_Y	0.623	0.99
209_A	212_N	0.621	0.99
267_A	332_I	0.621	0.99
29_V	33_V	0.621	0.99
14_G	41_A	0.619	0.99
31_A	104_S	0.619	0.99
362_I	432_M	0.618	0.99
92_V	124_I	0.613	0.99
130_L	146_V	0.612	0.99
322_A	330_A	0.612	0.99
27_E	32_I	0.608	0.99
338_H	346_F	0.606	0.99
240_A	313_M	0.605	0.99
123_F	150_S	0.604	0.99
23_G	28_N	0.603	0.99
479_L	482_T	0.603	0.99
259_V	316_I	0.602	0.99
41_A	128_V	0.602	0.99
267_A	328_W	0.599	0.99
492_T	495_I	0.599	0.99
8_I	132_L	0.599	0.99
151_Y	174_T	0.598	0.99
249_V	253_I	0.597	0.99
344_L	461_L	0.597	0.99
242_A	309_A	0.597	0.99
139_M	181_L	0.597	0.99
259_V	263_V	0.596	0.99
246_P	252_L	0.596	0.99
88_M	131_V	0.595	0.99
247_T	250_S	0.593	0.99
240_A	310_Y	0.591	0.98
18_L	34_G	0.589	0.98
80_V	198_R	0.589	0.98
369_R	380_L	0.588	0.98
336_M	467_V	0.588	0.98
116_F	249_V	0.588	0.98
81_L	85_S	0.587	0.98
127_M	146_V	0.587	0.98
98_L	343_A	0.586	0.98
8_I	15_F	0.586	0.98
311_S	315_Q	0.586	0.98
312_T	342_K	0.586	0.98
352_V	365_M	0.585	0.98
34_G	121_N	0.583	0.98
256_A	343_A	0.582	0.98
46_A	49_G	0.582	0.98
211_G	215_L	0.582	0.98
282_L	286_V	0.581	0.98
38_V	97_F	0.581	0.98
294_A	313_M	0.580	0.98
14_G	33_V	0.580	0.98
256_A	260_T	0.579	0.98
309_A	312_T	0.578	0.98
392_V	397_F	0.576	0.98
297_A	300_V	0.576	0.98
6_L	44_V	0.575	0.98
492_T	496_T	0.575	0.98
150_S	243_M	0.571	0.98
7_T	41_A	0.569	0.98
34_G	37_S	0.569	0.98
49_G	477_G	0.569	0.98
391_L	397_F	0.568	0.98
91_V	335_L	0.564	0.98
96_G	252_L	0.563	0.98
185_L	225_G	0.562	0.98
33_V	36_G	0.562	0.98
321_L	414_L	0.561	0.98
329_D	475_L	0.561	0.98
197_F	269_T	0.561	0.98
243_M	305_K	0.560	0.98
52_F	55_N	0.560	0.98
181_L	222_L	0.560	0.98
423_F	427_L	0.556	0.98
151_Y	167_A	0.555	0.98
134_D	268_R	0.554	0.98
403_L	419_L	0.553	0.98
382_G	464_S	0.553	0.98
154_I	253_I	0.552	0.98
250_S	338_H	0.551	0.98
321_L	406_A	0.550	0.98
43_L	46_A	0.548	0.98
419_L	422_A	0.548	0.98
39_G	42_A	0.547	0.97
48_I	51_D	0.547	0.97
484_E	487_H	0.547	0.97
333_F	397_F	0.546	0.97
171_F	178_D	0.545	0.97
143_W	181_L	0.544	0.97
243_M	256_A	0.544	0.97
11_P	14_G	0.544	0.97
5_A	9_I	0.544	0.97
23_G	26_S	0.542	0.97
92_V	96_G	0.541	0.97
284_G	325_V	0.540	0.97
388_A	399_K	0.539	0.97
310_Y	313_M	0.539	0.97
255_A	259_V	0.539	0.97
34_G	41_A	0.538	0.97
166_A	241_D	0.537	0.97
95_V	252_L	0.536	0.97
130_L	143_W	0.535	0.97
38_V	96_G	0.535	0.97
351_S	453_H	0.532	0.97
29_V	34_G	0.531	0.97
150_S	154_I	0.531	0.97
379_F	429_T	0.530	0.97
297_A	301_Q	0.530	0.97
365_M	368_L	0.529	0.97
250_S	253_I	0.529	0.97
21_S	26_S	0.528	0.97
220_L	282_L	0.528	0.97
341_F	386_L	0.527	0.97
343_A	460_L	0.527	0.97
274_L	277_P	0.526	0.97
246_P	249_V	0.524	0.97
334_H	337_T	0.524	0.97
48_I	81_L	0.523	0.97
180_F	183_F	0.523	0.97
429_T	433_I	0.521	0.97
288_A	292_L	0.521	0.97
210_D	218_A	0.520	0.97
140_Y	151_Y	0.519	0.97
9_I	13_I	0.518	0.97
215_L	273_F	0.518	0.97
7_T	24_R	0.518	0.97
38_V	44_V	0.517	0.96
16_V	19_A	0.516	0.96
319_M	335_L	0.516	0.96
154_I	245_G	0.516	0.96
341_F	394_A	0.515	0.96
352_V	375_V	0.515	0.96
119_Y	149_C	0.515	0.96
432_M	436_V	0.514	0.96
318_Y	402_I	0.513	0.96
426_S	430_F	0.512	0.96
276_T	280_L	0.512	0.96
375_V	457_L	0.512	0.96
295_G	424_M	0.511	0.96
379_F	433_I	0.511	0.96
212_N	278_E	0.511	0.96
174_T	258_M	0.511	0.96
103_A	117_F	0.510	0.96
7_T	22_R	0.510	0.96
109_G	358_H	0.510	0.96
367_G	373_P	0.510	0.96
468_G	471_I	0.509	0.96
444_H	447_A	0.509	0.96
174_T	256_A	0.509	0.96
197_F	272_L	0.509	0.96
263_V	319_M	0.508	0.96
333_F	467_V	0.507	0.96
461_L	465_T	0.507	0.96
7_T	11_P	0.506	0.96
351_S	355_A	0.505	0.96
147_G	174_T	0.504	0.96
29_V	37_S	0.503	0.96
397_F	468_G	0.503	0.96
290_T	320_F	0.503	0.96
458_I	461_L	0.502	0.96
87_T	474_P	0.502	0.96
315_Q	386_L	0.502	0.96
406_A	418_G	0.501	0.96
230_S	262_G	0.501	0.96
301_Q	310_Y	0.501	0.96
189_Y	193_G	0.501	0.96
304_I	365_M	0.500	0.96
38_V	48_I	0.500	0.96

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3rkoL	1	0.9967	100	0.12	Contact Map
4he8L	1	0.9592	100	0.176	Contact Map
3rkoM	1	0.7798	100	0.306	Contact Map
4he8M	1	0.7439	100	0.344	Contact Map
3rkoN	1	0.7325	100	0.358	Contact Map
4he8N	1	0.6949	100	0.401	Contact Map
4he8K	1	0.1517	53.7	0.97	Contact Map
3rkoK	1	0.1582	48.6	0.971	Contact Map
4o6yA	2	0.3377	15.5	0.977	Contact Map
2kv5A	1	0.0538	11.4	0.979	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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