SGRR - ECOLI - GREMLIN Contacts

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SGRR - HTH-type transcriptional regulator SgrR

UniProt:	P33595	Sequences: MPSARLQQQFIRLWQCCEGKSQDTTLNELAALLSCSRRHMRTLLNTMQDRGWLTWEAEVGRGKRSRLTFLYTGLALQQQRAEDLLEQDRIDQLVQLVGDKATVRQMLVSHLGRSFRQGRHILRVLYYRPLRNLLPGSALRRSETHIARQIFSSLTRINEENGELEADIAHHWQQISPLHWRFFLRPGVHFHHGRELEMDDVIASLKRINTLPLYSHIADIVSPTPWTLDIHLTQPDRWLPLLLGQVPAMILPREWETLSNFASHPIGTGPYAVIRNSTNQLKIQAFDDFFGYRALIDEVNVWVLPEIADEPAGGLMLKGPQGEEKEIESRLEEGCYYLLFDSRTHRGANQQVRDWVSYVLSPTNLVYFAEEQYQQLWFPAYGLLPRWHHARTIKSEKPAGLESLTLTFYQDHSEHRVIAGIMQQILASHQVTLKIKEIDYDQWHTGEIESDIWLNSANFTLPLDFSVFAHLCEVPLLQHCIPIDWQADAARWRNGEMNLANWCQQLVASKAMVPLLHHWLIIQGQRSMRGLRMNTLGWFDFKSAWFAPPDP	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG12094
Length:	551 (431)
Sequences:	19161 (14147)
Seq/√Len:	681.5

ECOLI - SGRR YBAE MPPA OPPA DPPA SAPA DDPA GSIB YGIS YEJA NIKA
BACSU - YHJP APPA OPPA DPPE
HALSA - Q9HMI3 Q9HMW4
SULSO - Q97VF7

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
274_I	284_Q	4.224	1.00
351_Q	403_S	3.450	1.00
223_P	229_D	3.345	1.00
221_V	229_D	3.336	1.00
396_E	399_A	3.232	1.00
186_P	226_W	3.210	1.00
363_T	367_Y	3.074	1.00
202_I	206_K	2.995	1.00
224_T	227_T	2.994	1.00
272_A	284_Q	2.950	1.00
490_A	495_G	2.862	1.00
345_H	348_A	2.743	1.00
202_I	222_S	2.690	1.00
121_I	298_E	2.566	1.00
358_Y	396_E	2.510	1.00
356_V	426_L	2.495	1.00
361_S	364_N	2.487	1.00
196_L	268_T	2.456	1.00
253_R	256_E	2.443	1.00
173_Q	183_F	2.441	1.00
399_A	403_S	2.430	1.00
171_H	183_F	2.413	1.00
158_N	163_E	2.396	1.00
427_A	432_T	2.347	1.00
221_V	231_H	2.313	1.00
158_N	165_E	2.305	1.00
179_H	229_D	2.295	1.00
194_R	254_E	2.284	1.00
155_T	172_W	2.281	1.00
351_Q	354_D	2.251	1.00
350_Q	354_D	2.247	1.00
191_H	286_F	2.234	1.00
199_D	222_S	2.231	1.00
405_T	434_K	2.219	1.00
351_Q	400_G	2.202	1.00
344_T	451_D	2.146	1.00
188_V	196_L	2.139	1.00
492_W	495_G	2.131	1.00
179_H	231_H	2.129	1.00
181_R	229_D	2.125	1.00
189_H	195_E	2.123	1.00
175_I	178_L	2.121	1.00
189_H	288_D	2.099	1.00
495_G	498_N	2.088	1.00
152_S	167_D	2.071	1.00
282_K	298_E	2.065	1.00
174_Q	180_W	2.059	1.00
121_I	300_N	2.029	1.00
498_N	501_N	2.011	1.00
205_L	230_I	2.005	1.00
134_L	207_R	1.994	1.00
197_E	200_D	1.962	1.00
183_F	227_T	1.933	1.00
218_A	233_T	1.926	1.00
201_V	228_L	1.891	1.00
478_Q	482_P	1.878	1.00
405_T	436_K	1.859	1.00
272_A	287_D	1.858	1.00
199_D	253_R	1.850	1.00
158_N	161_N	1.848	1.00
275_R	282_K	1.841	1.00
423_Q	427_A	1.818	1.00
350_Q	509_S	1.818	1.00
380_A	517_H	1.815	1.00
123_R	300_N	1.814	1.00
340_F	513_V	1.803	1.00
170_H	186_P	1.795	1.00
275_R	280_Q	1.757	1.00
252_P	255_W	1.755	1.00
504_Q	508_A	1.738	1.00
446_G	449_E	1.732	1.00
199_D	225_P	1.730	1.00
200_D	253_R	1.723	1.00
505_Q	509_S	1.711	1.00
487_A	499_L	1.699	1.00
359_V	429_H	1.678	1.00
192_H	252_P	1.667	1.00
284_Q	298_E	1.662	1.00
170_H	183_F	1.661	1.00
194_R	252_P	1.657	1.00
175_I	179_H	1.649	1.00
187_G	195_E	1.635	1.00
354_D	396_E	1.632	1.00
120_H	297_D	1.631	1.00
501_N	504_Q	1.626	1.00
199_D	202_I	1.624	1.00
280_Q	300_N	1.593	1.00
219_D	231_H	1.592	1.00
274_I	298_E	1.583	1.00
271_Y	296_I	1.580	1.00
198_M	222_S	1.580	1.00
170_H	185_R	1.579	1.00
285_A	297_D	1.578	1.00
155_T	182_F	1.560	1.00
354_D	510_K	1.556	1.00
398_P	402_E	1.553	1.00
340_F	452_I	1.551	1.00
197_E	225_P	1.547	1.00
416_R	420_G	1.529	1.00
350_Q	508_A	1.528	1.00
277_S	280_Q	1.525	1.00
172_W	182_F	1.516	1.00
393_I	396_E	1.516	1.00
352_V	401_L	1.507	1.00
357_S	510_K	1.498	1.00
360_L	422_M	1.497	1.00
181_R	227_T	1.485	1.00
439_D	442_Q	1.485	1.00
395_S	398_P	1.475	1.00
324_E	526_R	1.474	1.00
175_I	181_R	1.470	1.00
140_R	143_E	1.468	1.00
363_T	379_P	1.442	1.00
497_M	500_A	1.439	1.00
152_S	268_T	1.427	1.00
356_V	431_V	1.422	1.00
152_S	290_F	1.412	1.00
191_H	272_A	1.406	1.00
366_V	379_P	1.399	1.00
192_H	254_E	1.396	1.00
282_K	300_N	1.386	1.00
482_P	509_S	1.382	1.00
195_E	226_W	1.361	1.00
274_I	282_K	1.361	1.00
188_V	268_T	1.348	1.00
326_E	526_R	1.344	1.00
486_Q	495_G	1.342	1.00
436_K	446_G	1.331	1.00
425_I	428_S	1.323	1.00
123_R	302_W	1.318	1.00
119_R	297_D	1.304	1.00
189_H	286_F	1.299	1.00
202_I	220_I	1.297	1.00
230_I	239_L	1.295	1.00
223_P	227_T	1.290	1.00
408_F	435_I	1.274	1.00
168_I	268_T	1.269	1.00
347_G	356_V	1.268	1.00
183_F	226_W	1.265	1.00
473_E	483_I	1.260	1.00
472_C	485_W	1.256	1.00
366_V	377_W	1.255	1.00
386_R	517_H	1.235	1.00
222_S	225_P	1.233	1.00
440_Y	444_H	1.228	1.00
283_I	301_V	1.226	1.00
339_L	453_W	1.225	1.00
146_I	283_I	1.219	1.00
280_Q	302_W	1.217	1.00
421_I	425_I	1.215	1.00
206_K	210_T	1.199	1.00
220_I	228_L	1.193	1.00
494_N	497_M	1.189	1.00
218_A	231_H	1.178	1.00
424_Q	428_S	1.177	1.00
166_A	172_W	1.176	1.00
359_V	426_L	1.175	1.00
344_T	348_A	1.173	1.00
394_K	429_H	1.172	1.00
185_R	290_F	1.170	1.00
180_W	239_L	1.169	1.00
400_G	403_S	1.164	1.00
185_R	188_V	1.162	1.00
125_L	310_E	1.156	1.00
191_H	288_D	1.151	1.00
347_G	404_L	1.144	1.00
201_V	250_I	1.140	1.00
326_E	524_G	1.138	1.00
272_A	286_F	1.137	1.00
426_L	433_L	1.136	1.00
285_A	294_A	1.134	1.00
486_Q	490_A	1.132	1.00
156_R	167_D	1.128	1.00
399_A	402_E	1.124	1.00
423_Q	435_I	1.116	1.00
204_S	250_I	1.114	1.00
354_D	400_G	1.110	1.00
394_K	398_P	1.109	1.00
182_F	230_I	1.109	1.00
408_F	437_E	1.108	1.00
486_Q	501_N	1.105	1.00
540_D	543_S	1.105	1.00
463_L	496_E	1.097	1.00
203_A	253_R	1.093	1.00
350_Q	510_K	1.088	1.00
505_Q	508_A	1.079	1.00
255_W	266_I	1.077	1.00
234_Q	489_A	1.076	1.00
406_L	433_L	1.075	1.00
364_N	425_I	1.075	1.00
329_S	519_W	1.074	1.00
370_E	516_L	1.073	1.00
156_R	165_E	1.069	1.00
200_D	203_A	1.063	1.00
170_H	226_W	1.061	1.00
284_Q	287_D	1.060	1.00
423_Q	433_L	1.053	1.00
122_L	296_I	1.050	1.00
285_A	293_R	1.050	1.00
442_Q	446_G	1.048	1.00
328_E	524_G	1.047	1.00
196_L	250_I	1.047	1.00
168_I	201_V	1.047	1.00
191_H	266_I	1.045	1.00
494_N	498_N	1.041	1.00
478_Q	481_I	1.039	1.00
198_M	223_P	1.037	1.00
176_S	179_H	1.034	1.00
180_W	240_P	1.032	1.00
541_F	544_A	1.029	1.00
173_Q	181_R	1.028	1.00
180_W	232_L	1.027	1.00
190_F	200_D	1.026	1.00
261_F	265_P	1.025	1.00
422_M	426_L	1.020	1.00
311_P	314_G	1.019	1.00
502_W	505_Q	1.018	1.00
407_T	436_K	1.017	1.00
357_S	513_V	1.011	1.00
168_I	188_V	1.010	1.00
392_T	500_A	1.009	1.00
424_Q	427_A	1.004	1.00
357_S	362_P	0.998	1.00
378_F	519_W	0.998	1.00
129_P	276_N	0.993	1.00
118_G	295_L	0.990	1.00
186_P	195_E	0.989	1.00
479_H	482_P	0.987	1.00
370_E	377_W	0.986	1.00
394_K	428_S	0.984	1.00
417_V	420_G	0.984	1.00
340_F	356_V	0.982	1.00
396_E	400_G	0.981	1.00
206_K	209_N	0.976	1.00
183_F	186_P	0.971	1.00
354_D	358_Y	0.970	1.00
419_A	435_I	0.969	1.00
365_L	418_I	0.968	1.00
239_L	243_L	0.967	1.00
325_K	523_Q	0.963	1.00
354_D	508_A	0.962	1.00
195_E	225_P	0.962	1.00
395_S	399_A	0.955	1.00
427_A	431_V	0.948	1.00
364_N	368_F	0.946	1.00
366_V	516_L	0.945	1.00
485_W	489_A	0.942	1.00
200_D	204_S	0.942	1.00
122_L	528_M	0.938	1.00
202_I	228_L	0.935	1.00
153_S	249_M	0.934	1.00
362_P	379_P	0.930	1.00
168_I	196_L	0.927	1.00
153_S	167_D	0.924	1.00
181_R	223_P	0.924	1.00
198_M	228_L	0.923	1.00
135_P	251_L	0.915	1.00
378_F	386_R	0.915	1.00
191_H	267_G	0.913	1.00
404_L	452_I	0.911	1.00
199_D	203_A	0.910	1.00
232_L	239_L	0.910	1.00
291_G	542_K	0.909	1.00
150_I	283_I	0.908	1.00
315_L	321_Q	0.907	1.00
438_I	446_G	0.906	1.00
155_T	169_A	0.904	1.00
271_Y	294_A	0.897	1.00
493_R	497_M	0.896	1.00
151_F	267_G	0.895	1.00
367_Y	375_Q	0.895	1.00
361_S	425_I	0.891	1.00
192_H	266_I	0.889	1.00
355_W	401_L	0.889	1.00
501_N	505_Q	0.887	1.00
177_P	181_R	0.887	1.00
117_Q	120_H	0.886	1.00
182_F	240_P	0.884	1.00
183_F	224_T	0.883	1.00
359_V	394_K	0.880	1.00
222_S	228_L	0.877	1.00
236_D	242_L	0.877	1.00
155_T	240_P	0.872	1.00
334_G	458_N	0.866	1.00
178_L	231_H	0.865	1.00
216_H	236_D	0.862	1.00
206_K	220_I	0.859	1.00
204_S	251_L	0.856	1.00
149_Q	283_I	0.856	1.00
152_S	289_F	0.856	1.00
260_N	263_S	0.855	1.00
486_Q	489_A	0.854	1.00
155_T	164_L	0.849	1.00
178_L	218_A	0.849	1.00
216_H	234_Q	0.843	1.00
412_H	415_H	0.842	1.00
150_I	273_V	0.842	1.00
447_E	453_W	0.840	1.00
191_H	273_V	0.839	1.00
322_G	325_K	0.838	1.00
120_H	296_I	0.835	1.00
392_T	504_Q	0.833	1.00
475_P	478_Q	0.833	1.00
468_F	472_C	0.831	1.00
129_P	303_V	0.829	1.00
342_S	511_A	0.828	1.00
285_A	296_I	0.824	1.00
500_A	504_Q	0.822	1.00
531_L	544_A	0.821	1.00
188_V	226_W	0.820	1.00
174_Q	177_P	0.819	1.00
401_L	431_V	0.819	1.00
169_A	182_F	0.818	1.00
485_W	488_D	0.818	1.00
487_A	502_W	0.818	1.00
261_F	264_H	0.813	1.00
331_L	519_W	0.808	1.00
136_G	208_I	0.808	1.00
116_R	295_L	0.808	1.00
360_L	365_L	0.805	1.00
257_T	260_N	0.805	1.00
283_I	299_V	0.804	1.00
188_V	290_F	0.803	1.00
136_G	207_R	0.803	1.00
187_G	226_W	0.802	1.00
125_L	304_L	0.802	1.00
338_L	452_I	0.798	1.00
383_L	514_P	0.797	1.00
149_Q	299_V	0.797	1.00
260_N	264_H	0.797	1.00
405_T	451_D	0.795	1.00
358_Y	400_G	0.795	1.00
397_K	429_H	0.793	1.00
404_L	433_L	0.791	1.00
182_F	243_L	0.790	1.00
336_Y	415_H	0.785	1.00
276_N	281_L	0.783	1.00
120_H	295_L	0.780	1.00
349_N	352_V	0.779	1.00
220_I	230_I	0.778	1.00
222_S	229_D	0.776	1.00
172_W	240_P	0.776	1.00
178_L	234_Q	0.774	1.00
273_V	281_L	0.773	1.00
190_F	250_I	0.771	1.00
122_L	299_V	0.769	1.00
160_E	532_R	0.768	1.00
420_G	435_I	0.768	1.00
203_A	256_E	0.765	1.00
150_I	267_G	0.761	1.00
196_L	204_S	0.757	1.00
138_A	147_A	0.757	1.00
194_R	200_D	0.756	1.00
365_L	421_I	0.756	1.00
338_L	422_M	0.755	1.00
217_I	220_I	0.754	1.00
205_L	243_L	0.754	1.00
382_G	503_C	0.753	1.00
190_F	254_E	0.752	1.00
356_V	452_I	0.750	1.00
190_F	267_G	0.750	1.00
129_P	278_T	0.749	1.00
416_R	437_E	0.747	1.00
107_L	110_H	0.743	1.00
167_D	290_F	0.742	1.00
340_F	347_G	0.741	1.00
420_G	423_Q	0.739	1.00
106_M	109_S	0.739	1.00
329_S	376_L	0.739	1.00
184_L	196_L	0.735	1.00
360_L	426_L	0.734	1.00
209_N	233_T	0.734	1.00
443_W	453_W	0.734	1.00
511_A	514_P	0.734	1.00
154_L	169_A	0.733	1.00
426_L	452_I	0.731	1.00
525_Q	528_M	0.731	1.00
119_R	295_L	0.729	1.00
252_P	266_I	0.727	1.00
291_G	294_A	0.725	1.00
178_L	235_P	0.725	1.00
198_M	202_I	0.724	1.00
196_L	226_W	0.716	1.00
356_V	513_V	0.711	1.00
442_Q	445_T	0.709	1.00
284_Q	297_D	0.707	1.00
190_F	268_T	0.706	1.00
157_I	244_G	0.706	1.00
329_S	521_I	0.701	1.00
237_R	496_E	0.697	1.00
440_Y	455_N	0.694	1.00
151_F	265_P	0.691	1.00
287_D	297_D	0.690	1.00
418_I	422_M	0.690	1.00
271_Y	298_E	0.690	1.00
413_S	417_V	0.690	1.00
472_C	475_P	0.688	1.00
311_P	322_G	0.688	1.00
197_E	226_W	0.684	1.00
184_L	226_W	0.683	1.00
272_A	288_D	0.682	1.00
407_T	410_Q	0.682	1.00
146_I	281_L	0.680	1.00
427_A	433_L	0.679	1.00
273_V	276_N	0.677	1.00
306_E	309_D	0.677	1.00
496_E	499_L	0.677	1.00
202_I	221_V	0.676	1.00
172_W	183_F	0.675	1.00
299_V	541_F	0.673	1.00
344_T	347_G	0.671	1.00
407_T	446_G	0.671	1.00
422_M	433_L	0.671	1.00
144_T	246_V	0.670	1.00
408_F	416_R	0.669	1.00
177_P	491_R	0.669	1.00
304_L	310_E	0.666	1.00
347_G	352_V	0.666	1.00
153_S	268_T	0.661	1.00
401_L	429_H	0.661	1.00
190_F	196_L	0.658	1.00
426_L	429_H	0.657	1.00
418_I	516_L	0.656	1.00
157_I	164_L	0.656	1.00
296_I	528_M	0.654	1.00
323_E	526_R	0.652	1.00
131_R	140_R	0.652	1.00
203_A	207_R	0.651	1.00
460_T	466_S	0.649	1.00
465_F	488_D	0.648	1.00
234_Q	485_W	0.646	1.00
138_A	143_E	0.646	1.00
438_I	443_W	0.646	1.00
151_F	268_T	0.644	1.00
216_H	233_T	0.643	1.00
438_I	442_Q	0.642	1.00
365_L	422_M	0.641	1.00
524_G	531_L	0.639	1.00
390_A	497_M	0.639	1.00
116_R	120_H	0.638	1.00
407_T	438_I	0.637	1.00
151_F	261_F	0.636	1.00
203_A	251_L	0.636	1.00
206_K	219_D	0.635	1.00
335_C	380_A	0.635	1.00
360_L	513_V	0.634	1.00
376_L	521_I	0.634	1.00
179_H	221_V	0.633	1.00
154_L	201_V	0.633	1.00
343_R	348_A	0.633	1.00
326_E	529_R	0.633	1.00
152_S	291_G	0.632	1.00
420_G	424_Q	0.631	1.00
326_E	525_Q	0.630	1.00
474_V	483_I	0.629	1.00
407_T	450_S	0.628	1.00
389_H	493_R	0.628	1.00
166_A	171_H	0.624	1.00
203_A	254_E	0.623	1.00
426_L	431_V	0.621	1.00
338_L	515_L	0.621	1.00
408_F	419_A	0.618	1.00
174_Q	240_P	0.616	1.00
398_P	429_H	0.616	1.00
344_T	449_E	0.614	1.00
363_T	366_V	0.614	1.00
413_S	416_R	0.614	1.00
392_T	503_C	0.614	1.00
461_L	465_F	0.614	1.00
238_W	463_L	0.614	1.00
409_Y	415_H	0.612	1.00
156_R	291_G	0.610	1.00
444_H	448_I	0.608	1.00
471_L	512_M	0.608	1.00
324_E	525_Q	0.607	1.00
394_K	401_L	0.607	1.00
198_M	224_T	0.607	1.00
411_D	416_R	0.607	1.00
285_A	292_Y	0.605	1.00
281_L	303_V	0.605	1.00
124_V	541_F	0.604	1.00
360_L	515_L	0.603	1.00
149_Q	301_V	0.603	1.00
273_V	283_I	0.602	1.00
406_L	419_A	0.602	1.00
336_Y	418_I	0.600	1.00
404_L	407_T	0.600	1.00
184_L	201_V	0.600	1.00
346_R	451_D	0.599	1.00
192_H	255_W	0.594	1.00
126_Y	130_L	0.594	1.00
249_M	252_P	0.593	1.00
279_N	302_W	0.592	1.00
493_R	496_E	0.591	1.00
147_A	151_F	0.591	1.00
433_L	452_I	0.591	1.00
342_S	348_A	0.590	1.00
206_K	253_R	0.589	1.00
490_A	496_E	0.589	1.00
347_G	452_I	0.588	1.00
337_Y	512_M	0.588	1.00
133_L	276_N	0.588	1.00
340_F	357_S	0.586	1.00
126_Y	301_V	0.586	1.00
276_N	303_V	0.583	1.00
262_A	265_P	0.583	1.00
206_K	216_H	0.581	1.00
337_Y	455_N	0.579	1.00
164_L	240_P	0.579	1.00
487_A	496_E	0.579	1.00
198_M	226_W	0.578	1.00
476_L	482_P	0.577	1.00
251_L	255_W	0.576	1.00
383_L	512_M	0.575	1.00
271_Y	285_A	0.574	1.00
217_I	230_I	0.573	1.00
251_L	254_E	0.573	1.00
258_L	261_F	0.573	1.00
444_H	447_E	0.573	1.00
510_K	513_V	0.572	1.00
121_I	282_K	0.572	1.00
105_Q	108_V	0.571	1.00
388_H	391_R	0.571	1.00
131_R	143_E	0.571	1.00
136_G	204_S	0.565	1.00
155_T	243_L	0.565	1.00
259_S	263_S	0.564	1.00
191_H	268_T	0.563	1.00
150_I	265_P	0.563	1.00
190_F	194_R	0.562	1.00
133_L	281_L	0.562	1.00
404_L	408_F	0.561	1.00
415_H	454_L	0.560	1.00
287_D	293_R	0.559	1.00
465_F	469_A	0.558	1.00
132_N	262_A	0.558	1.00
540_D	544_A	0.558	1.00
122_L	544_A	0.557	1.00
415_H	456_S	0.557	1.00
366_V	370_E	0.557	1.00
473_E	476_L	0.556	1.00
190_F	204_S	0.556	1.00
200_D	254_E	0.555	1.00
304_L	309_D	0.553	1.00
197_E	253_R	0.553	1.00
155_T	244_G	0.553	1.00
425_I	429_H	0.551	1.00
365_L	369_A	0.551	1.00
182_F	228_L	0.550	1.00
352_V	356_V	0.550	1.00
307_I	310_E	0.550	1.00
194_R	253_R	0.549	1.00
468_F	488_D	0.549	1.00
351_Q	399_A	0.548	1.00
522_I	531_L	0.548	1.00
119_R	298_E	0.548	1.00
222_S	227_T	0.547	1.00
296_I	299_V	0.547	1.00
539_F	544_A	0.547	1.00
200_D	251_L	0.546	1.00
457_A	470_H	0.546	1.00
462_P	496_E	0.545	1.00
331_L	378_F	0.545	1.00
474_V	478_Q	0.544	1.00
198_M	227_T	0.543	1.00
206_K	222_S	0.543	1.00
507_V	510_K	0.543	1.00
356_V	404_L	0.543	1.00
405_T	432_T	0.541	1.00
265_P	273_V	0.541	1.00
196_L	267_G	0.538	1.00
115_F	118_G	0.537	1.00
465_F	499_L	0.537	1.00
196_L	201_V	0.537	1.00
184_L	188_V	0.537	1.00
407_T	434_K	0.536	1.00
477_L	482_P	0.536	1.00
196_L	200_D	0.535	1.00
323_E	326_E	0.535	1.00
457_A	460_T	0.535	1.00
140_R	440_Y	0.535	1.00
195_E	200_D	0.535	1.00
190_F	197_E	0.533	1.00
132_N	137_S	0.532	1.00
464_D	468_F	0.532	1.00
347_G	451_D	0.532	1.00
198_M	225_P	0.532	1.00
508_A	511_A	0.531	1.00
285_A	295_L	0.530	1.00
524_G	528_M	0.530	1.00
336_Y	518_H	0.530	1.00
358_Y	429_H	0.529	1.00
443_W	447_E	0.529	1.00
322_G	526_R	0.529	1.00
208_I	247_P	0.528	1.00
343_R	481_I	0.528	1.00
263_S	278_T	0.528	1.00
184_L	198_M	0.528	1.00
134_L	262_A	0.527	1.00
215_S	233_T	0.527	1.00
358_Y	397_K	0.527	1.00
365_L	515_L	0.527	1.00
286_F	289_F	0.527	1.00
147_A	150_I	0.527	1.00
476_L	479_H	0.527	1.00
383_L	506_L	0.526	1.00
141_R	458_N	0.525	1.00
338_L	454_L	0.525	1.00
116_R	119_R	0.524	1.00
152_S	196_L	0.523	1.00
445_T	448_I	0.522	1.00
401_L	430_Q	0.520	0.99
490_A	493_R	0.520	0.99
471_L	506_L	0.519	0.99
168_I	184_L	0.518	0.99
146_I	301_V	0.517	0.99
174_Q	178_L	0.517	0.99
130_L	281_L	0.517	0.99
332_E	520_L	0.516	0.99
393_I	399_A	0.516	0.99
404_L	431_V	0.515	0.99
409_Y	412_H	0.514	0.99
292_Y	295_L	0.514	0.99
141_R	144_T	0.514	0.99
271_Y	544_A	0.513	0.99
491_R	495_G	0.513	0.99
502_W	506_L	0.512	0.99
364_N	421_I	0.511	0.99
202_I	223_P	0.511	0.99
422_M	454_L	0.510	0.99
454_L	515_L	0.510	0.99
380_A	514_P	0.509	0.99
161_N	165_E	0.507	0.99
423_Q	432_T	0.507	0.99
294_A	542_K	0.506	0.99
503_C	507_V	0.505	0.99
421_I	424_Q	0.505	0.99
113_R	116_R	0.504	0.99
347_G	431_V	0.504	0.99
220_I	223_P	0.502	0.99
389_H	497_M	0.502	0.99
325_K	526_R	0.501	0.99
477_L	480_C	0.501	0.99
205_L	220_I	0.501	0.99
302_W	314_G	0.500	0.99
472_C	478_Q	0.500	0.99

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3zs6A	1	0.7768	100	0.402	Contact Map
4tozA	1	0.7967	100	0.405	Contact Map
1xocA	2	0.775	100	0.405	Contact Map
2wolA	1	0.8149	100	0.406	Contact Map
1jetA	1	0.7931	100	0.406	Contact Map
4qflA	1	0.7713	100	0.407	Contact Map
3m8uA	1	0.775	100	0.408	Contact Map
1dpeA	1	0.7713	100	0.412	Contact Map
3tpaA	1	0.7731	100	0.414	Contact Map
4wedA	1	0.7568	100	0.416	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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