BGLX - ECOLI - GREMLIN Contacts

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BGLX - Periplasmic beta-glucosidase

UniProt:	P33363	Sequences: MKWLCSVGIAVSLALQPALADDLFGNHPLTPEARDAFVTELLKKMTVDEKIGQLRLISVGPDNPKEAIREMIKDGQVGAIFNTVTRQDIRAMQDQVMELSRLKIPLFFAYDVLHGQRTVFPISLGLASSFNLDAVKTVGRVSAYEAADDGLNMTWAPMVDVSRDPRWGRASEGFGEDTYLTSTMGKTMVEAMQGKSPADRYSVMTSVKHFAAYGAVEGGKEYNTVDMSPQRLFNDYMPPYKAGLDAGSGAVMVALNSLNGTPATSDSWLLKDVLRDQWGFKGITVSDHGAIKELIKHGTAADPEDAVRVALKSGINMSMSDEYYSKYLPGLIKSGKVTMAELDDAARHVLNVKYDMGLFNDPYSHLGPKESDPVDTNAESRLHRKEAREVARESLVLLKNRLETLPLKKSATIAVVGPLADSKRDVMGSWSAAGVADQSVTVLTGIKNAVGENGKVLYAKGANVTSDKGIIDFLNQYEEAVKVDPRSPQEMIDEAVQTAKQSDVVVAVVGEAQGMAHEASSRTDITIPQSQRDLIAALKATGKPLVLVLMNGRPLALVKEDQQADAILETWFAGTEGGNAIADVLFGDYNPSGKLPMSFPRSVGQIPVYYSHLNTGRPYNADKPNKYTSRYFDEANGALYPFGYGLSYTTFTVSDVKLSAPTMKRDGKVTASVQVTNTGKREGATVVQMYLQDVTASMSRPVKQLKGFEKITLKPGETQTVSFPIDIEALKFWNQQMKYDAEPGKFNVFIGTDSARVKKGEFELL	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG12013
Length:	765 (633)
Sequences:	6763 (4944)
Seq/√Len:	196.5

ECOLI - BGLX
BACSU - NAGZ
SULSO - Q97UI4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
392_R	583_D	4.237	1.00
682_E	715_P	3.886	1.00
676_T	718_T	3.776	1.00
137_T	389_E	3.769	1.00
682_E	714_K	3.748	1.00
674_Q	718_T	3.590	1.00
136_K	190_E	3.415	1.00
131_N	393_E	3.332	1.00
650_T	678_T	3.209	1.00
649_T	679_G	3.125	1.00
389_E	393_E	3.047	1.00
655_D	674_Q	3.038	1.00
233_F	277_Q	3.025	1.00
449_A	588_D	2.994	1.00
551_N	569_E	2.923	1.00
312_K	341_E	2.836	1.00
590_N	683_G	2.798	1.00
509_V	535_I	2.723	1.00
707_G	723_F	2.679	1.00
653_V	752_T	2.671	1.00
684_A	712_T	2.660	1.00
128_S	596_P	2.593	1.00
395_L	584_V	2.548	1.00
141_V	386_E	2.518	1.00
212_A	227_M	2.493	1.00
672_S	720_T	2.492	1.00
392_R	589_Y	2.490	1.00
267_S	272_D	2.439	1.00
138_V	390_V	2.439	1.00
450_V	586_F	2.432	1.00
442_V	508_V	2.422	1.00
388_R	583_D	2.390	1.00
228_S	231_R	2.356	1.00
182_S	242_A	2.343	1.00
673_V	687_V	2.341	1.00
590_N	647_S	2.335	1.00
207_V	248_S	2.328	1.00
752_T	758_K	2.301	1.00
670_T	722_S	2.259	1.00
689_M	723_F	2.239	1.00
693_D	746_F	2.223	1.00
547_L	564_A	2.221	1.00
684_A	710_K	2.215	1.00
694_V	747_N	2.206	1.00
726_D	729_A	2.165	1.00
459_A	494_E	2.162	1.00
132_L	183_T	2.145	1.00
272_D	276_D	2.129	1.00
316_N	348_H	2.125	1.00
682_E	712_T	2.117	1.00
703_K	749_F	2.100	1.00
446_I	586_F	2.084	1.00
674_Q	720_T	2.080	1.00
206_S	250_A	2.079	1.00
393_E	684_A	2.073	1.00
584_V	589_Y	2.063	1.00
275_R	344_D	2.062	1.00
267_S	271_K	2.033	1.00
268_W	273_V	1.992	1.00
253_V	264_T	1.984	1.00
161_V	235_D	1.975	1.00
388_R	392_R	1.965	1.00
537_A	540_A	1.960	1.00
204_M	249_G	1.952	1.00
583_D	588_D	1.948	1.00
649_T	683_G	1.944	1.00
536_A	563_Q	1.941	1.00
189_V	243_G	1.937	1.00
672_S	722_S	1.932	1.00
443_L	447_K	1.911	1.00
412_T	455_K	1.901	1.00
125_G	394_S	1.891	1.00
409_K	588_D	1.871	1.00
183_T	242_A	1.871	1.00
752_T	756_R	1.867	1.00
329_P	333_K	1.865	1.00
268_W	272_D	1.862	1.00
714_K	717_E	1.853	1.00
713_L	719_Q	1.843	1.00
330_G	334_S	1.823	1.00
576_E	579_N	1.817	1.00
670_T	724_P	1.807	1.00
384_R	576_E	1.776	1.00
560_E	567_I	1.772	1.00
656_V	759_K	1.768	1.00
254_A	263_A	1.758	1.00
120_F	141_V	1.758	1.00
507_A	538_L	1.748	1.00
692_Q	747_N	1.744	1.00
338_T	341_E	1.734	1.00
412_T	457_L	1.731	1.00
497_Q	501_Q	1.727	1.00
734_N	740_D	1.723	1.00
388_R	579_N	1.722	1.00
654_S	674_Q	1.721	1.00
448_N	579_N	1.708	1.00
249_G	355_D	1.703	1.00
283_I	352_V	1.701	1.00
652_T	676_T	1.669	1.00
668_K	724_P	1.662	1.00
633_D	755_A	1.660	1.00
538_L	545_L	1.660	1.00
132_L	709_E	1.655	1.00
505_V	538_L	1.652	1.00
692_Q	749_F	1.645	1.00
312_K	338_T	1.638	1.00
573_A	577_G	1.629	1.00
381_R	385_K	1.628	1.00
341_E	344_D	1.621	1.00
641_P	644_Y	1.617	1.00
443_L	458_Y	1.615	1.00
526_T	556_A	1.613	1.00
697_S	742_E	1.611	1.00
506_V	548_V	1.610	1.00
401_R	565_D	1.610	1.00
653_V	685_T	1.606	1.00
407_L	504_V	1.605	1.00
651_F	683_G	1.603	1.00
183_T	186_K	1.598	1.00
561_D	640_Y	1.585	1.00
328_L	337_V	1.578	1.00
391_A	580_A	1.561	1.00
654_S	676_T	1.560	1.00
161_V	627_Y	1.549	1.00
685_T	752_T	1.543	1.00
533_D	537_A	1.540	1.00
700_R	704_Q	1.529	1.00
594_K	685_T	1.527	1.00
229_P	233_F	1.527	1.00
402_L	565_D	1.525	1.00
135_V	184_M	1.524	1.00
637_G	755_A	1.522	1.00
451_G	454_G	1.520	1.00
544_P	565_D	1.520	1.00
136_K	140_R	1.519	1.00
497_Q	500_K	1.509	1.00
159_V	185_G	1.506	1.00
734_N	738_K	1.502	1.00
413_I	504_V	1.501	1.00
159_V	207_V	1.490	1.00
530_S	533_D	1.485	1.00
421_D	443_L	1.480	1.00
539_K	564_A	1.471	1.00
379_E	384_R	1.471	1.00
126_L	135_V	1.471	1.00
691_L	706_K	1.466	1.00
271_K	276_D	1.461	1.00
404_T	566_A	1.457	1.00
94_D	98_E	1.457	1.00
548_V	570_T	1.454	1.00
492_I	496_V	1.451	1.00
713_L	717_E	1.446	1.00
570_T	573_A	1.444	1.00
412_T	501_Q	1.441	1.00
311_L	345_A	1.441	1.00
258_L	263_A	1.441	1.00
592_S	684_A	1.431	1.00
79_A	82_N	1.427	1.00
457_L	501_Q	1.422	1.00
641_P	753_D	1.422	1.00
339_M	343_D	1.422	1.00
549_L	569_E	1.413	1.00
118_T	387_A	1.406	1.00
686_V	710_K	1.400	1.00
691_L	748_V	1.398	1.00
539_K	565_D	1.393	1.00
343_D	346_A	1.392	1.00
445_G	582_A	1.392	1.00
457_L	502_S	1.390	1.00
329_P	332_I	1.386	1.00
207_V	251_V	1.382	1.00
659_S	670_T	1.381	1.00
389_E	392_R	1.372	1.00
204_M	352_V	1.371	1.00
536_A	559_K	1.368	1.00
697_S	732_F	1.366	1.00
446_I	456_V	1.364	1.00
442_V	581_I	1.361	1.00
416_V	507_A	1.348	1.00
601_R	637_G	1.346	1.00
751_G	757_V	1.346	1.00
440_V	579_N	1.344	1.00
507_A	535_I	1.344	1.00
498_T	502_S	1.343	1.00
270_L	284_T	1.343	1.00
404_T	565_D	1.342	1.00
136_K	194_G	1.341	1.00
140_R	194_G	1.340	1.00
78_G	347_R	1.338	1.00
415_V	446_I	1.325	1.00
261_T	266_D	1.321	1.00
652_T	678_T	1.317	1.00
274_L	284_T	1.312	1.00
440_V	445_G	1.309	1.00
345_A	348_H	1.305	1.00
504_V	546_V	1.299	1.00
711_I	721_V	1.291	1.00
568_L	585_L	1.286	1.00
312_K	337_V	1.284	1.00
244_L	251_V	1.282	1.00
414_A	502_S	1.279	1.00
594_K	752_T	1.277	1.00
457_L	498_T	1.272	1.00
689_M	750_I	1.272	1.00
244_L	248_S	1.272	1.00
509_V	549_L	1.271	1.00
641_P	755_A	1.269	1.00
211_A	269_L	1.266	1.00
388_R	576_E	1.264	1.00
183_T	245_D	1.257	1.00
253_V	290_A	1.256	1.00
340_A	343_D	1.256	1.00
136_K	191_A	1.255	1.00
186_K	242_A	1.253	1.00
411_A	504_V	1.248	1.00
137_T	140_R	1.244	1.00
459_A	498_T	1.243	1.00
656_V	750_I	1.242	1.00
533_D	536_A	1.237	1.00
253_V	270_L	1.237	1.00
682_E	713_L	1.237	1.00
753_D	756_R	1.236	1.00
393_E	710_K	1.226	1.00
126_L	138_V	1.224	1.00
725_I	730_L	1.223	1.00
570_T	581_I	1.222	1.00
286_S	291_I	1.217	1.00
251_V	274_L	1.210	1.00
532_R	536_A	1.209	1.00
731_K	741_A	1.206	1.00
673_V	759_K	1.206	1.00
559_K	563_Q	1.206	1.00
696_A	742_E	1.192	1.00
170_A	597_M	1.190	1.00
76_Q	79_A	1.189	1.00
496_V	537_A	1.186	1.00
395_L	570_T	1.184	1.00
179_Y	707_G	1.183	1.00
491_M	494_E	1.181	1.00
449_A	583_D	1.169	1.00
127_A	596_P	1.162	1.00
156_A	192_M	1.157	1.00
330_G	333_K	1.149	1.00
638_A	641_P	1.149	1.00
264_T	290_A	1.146	1.00
399_K	640_Y	1.144	1.00
250_A	283_I	1.142	1.00
496_V	500_K	1.141	1.00
660_A	667_G	1.141	1.00
241_K	245_D	1.139	1.00
731_K	739_Y	1.139	1.00
207_V	243_G	1.138	1.00
332_I	342_L	1.137	1.00
415_V	443_L	1.133	1.00
460_K	463_N	1.133	1.00
271_K	313_S	1.126	1.00
76_Q	80_I	1.121	1.00
141_V	383_H	1.120	1.00
129_S	390_V	1.118	1.00
493_D	497_Q	1.117	1.00
505_V	545_L	1.117	1.00
671_A	689_M	1.115	1.00
188_M	192_M	1.113	1.00
234_N	733_W	1.111	1.00
237_M	273_V	1.111	1.00
263_A	266_D	1.105	1.00
192_M	205_T	1.105	1.00
647_S	683_G	1.103	1.00
183_T	708_F	1.100	1.00
732_F	742_E	1.100	1.00
495_A	499_A	1.099	1.00
673_V	723_F	1.097	1.00
85_T	332_I	1.095	1.00
526_T	532_R	1.095	1.00
281_K	355_D	1.092	1.00
658_L	671_A	1.091	1.00
185_G	243_G	1.088	1.00
489_Q	493_D	1.087	1.00
508_V	581_I	1.086	1.00
238_P	242_A	1.085	1.00
253_V	315_I	1.084	1.00
549_L	557_L	1.081	1.00
579_N	583_D	1.081	1.00
136_K	187_T	1.077	1.00
132_L	187_T	1.072	1.00
657_K	672_S	1.070	1.00
99_L	102_L	1.067	1.00
230_Q	698_M	1.066	1.00
649_T	678_T	1.066	1.00
354_Y	359_F	1.065	1.00
190_E	246_A	1.064	1.00
396_V	571_W	1.061	1.00
733_W	739_Y	1.061	1.00
694_V	745_K	1.058	1.00
230_Q	234_N	1.057	1.00
311_L	328_L	1.055	1.00
145_E	383_H	1.055	1.00
229_P	268_W	1.054	1.00
159_V	243_G	1.053	1.00
709_E	719_Q	1.052	1.00
134_A	386_E	1.051	1.00
675_V	687_V	1.050	1.00
193_Q	205_T	1.049	1.00
413_I	450_V	1.045	1.00
673_V	750_I	1.042	1.00
492_I	537_A	1.040	1.00
75_G	80_I	1.038	1.00
681_R	715_P	1.033	1.00
182_S	186_K	1.031	1.00
749_F	757_V	1.031	1.00
671_A	750_I	1.031	1.00
231_R	624_P	1.031	1.00
229_P	737_M	1.029	1.00
129_S	394_S	1.028	1.00
567_I	640_Y	1.028	1.00
496_V	541_T	1.028	1.00
706_K	729_A	1.027	1.00
733_W	737_M	1.026	1.00
395_L	568_L	1.025	1.00
186_K	190_E	1.022	1.00
85_T	88_D	1.021	1.00
449_A	586_F	1.020	1.00
446_I	585_L	1.015	1.00
332_I	338_T	1.014	1.00
333_K	339_M	1.014	1.00
87_Q	101_R	1.014	1.00
444_T	448_N	1.012	1.00
144_Y	195_K	1.011	1.00
505_V	543_K	1.009	1.00
317_M	349_V	1.007	1.00
243_G	248_S	1.006	1.00
271_K	344_D	1.005	1.00
689_M	725_I	0.999	1.00
327_Y	330_G	0.998	1.00
539_K	545_L	0.996	1.00
590_N	681_R	0.994	1.00
154_T	192_M	0.993	1.00
602_S	605_Q	0.991	1.00
594_K	686_V	0.990	1.00
326_K	330_G	0.989	1.00
711_I	719_Q	0.985	1.00
133_D	709_E	0.983	0.99
594_K	754_S	0.983	0.99
88_D	343_D	0.983	0.99
446_I	582_A	0.982	0.99
140_R	195_K	0.980	0.99
133_D	137_T	0.977	0.99
509_V	547_L	0.977	0.99
179_Y	183_T	0.976	0.99
601_R	639_L	0.975	0.99
416_V	505_V	0.974	0.99
706_K	725_I	0.973	0.99
535_I	560_E	0.973	0.99
557_L	639_L	0.970	0.99
385_K	389_E	0.970	0.99
742_E	746_F	0.969	0.99
134_A	390_V	0.968	0.99
407_L	546_V	0.965	0.99
441_T	444_T	0.963	0.99
126_L	390_V	0.962	0.99
413_I	586_F	0.961	0.99
165_P	606_I	0.960	0.99
458_Y	461_G	0.959	0.99
238_P	241_K	0.958	0.99
286_S	315_I	0.957	0.99
489_Q	533_D	0.956	0.99
153_M	250_A	0.954	0.99
93_Q	97_M	0.953	0.99
592_S	710_K	0.953	0.99
186_K	246_A	0.952	0.99
547_L	560_E	0.951	0.99
440_V	578_G	0.947	0.99
158_M	173_G	0.946	0.99
241_K	728_E	0.943	0.99
725_I	729_A	0.942	0.99
529_Q	533_D	0.941	0.99
751_G	754_S	0.939	0.99
414_A	505_V	0.936	0.99
541_T	544_P	0.934	0.99
600_P	606_I	0.933	0.99
547_L	567_I	0.932	0.99
412_T	503_D	0.931	0.99
174_F	184_M	0.930	0.99
594_K	653_V	0.928	0.99
244_L	280_F	0.928	0.99
700_R	732_F	0.928	0.99
140_R	144_Y	0.926	0.99
408_K	681_R	0.921	0.99
263_A	269_L	0.920	0.99
525_I	556_A	0.917	0.99
693_D	696_A	0.916	0.99
517_H	520_S	0.916	0.99
132_L	708_F	0.914	0.99
654_S	718_T	0.912	0.99
550_M	570_T	0.911	0.99
257_S	699_S	0.911	0.99
657_K	720_T	0.910	0.99
693_D	744_G	0.909	0.99
442_V	550_M	0.908	0.99
404_T	504_V	0.908	0.99
669_V	730_L	0.906	0.99
137_T	386_E	0.905	0.99
728_E	731_K	0.904	0.99
241_K	278_W	0.904	0.99
415_V	420_A	0.903	0.99
331_L	336_K	0.902	0.99
568_L	591_P	0.902	0.99
543_K	565_D	0.901	0.99
228_S	735_Q	0.900	0.99
244_L	278_W	0.900	0.99
494_E	498_T	0.899	0.99
94_D	97_M	0.898	0.99
663_M	669_V	0.897	0.99
377_N	380_S	0.896	0.99
709_E	721_V	0.895	0.99
558_V	639_L	0.890	0.99
86_R	329_P	0.890	0.99
689_M	748_V	0.887	0.99
421_D	441_T	0.885	0.99
606_I	632_F	0.885	0.99
414_A	498_T	0.877	0.99
129_S	184_M	0.875	0.99
211_A	237_M	0.874	0.99
656_V	671_A	0.872	0.99
505_V	542_G	0.871	0.99
658_L	663_M	0.870	0.99
224_T	257_S	0.870	0.99
644_Y	753_D	0.869	0.99
144_Y	383_H	0.869	0.99
443_L	456_V	0.868	0.99
583_D	589_Y	0.867	0.99
332_I	337_V	0.866	0.99
445_G	449_A	0.866	0.99
161_V	181_T	0.865	0.99
444_T	447_K	0.865	0.99
265_S	293_E	0.864	0.99
446_I	506_V	0.862	0.99
242_A	245_D	0.862	0.99
275_R	348_H	0.858	0.99
133_D	136_K	0.857	0.99
146_A	154_T	0.855	0.99
265_S	294_L	0.854	0.99
75_G	79_A	0.854	0.99
143_A	192_M	0.852	0.99
626_K	699_S	0.851	0.99
88_D	91_A	0.850	0.99
462_A	530_S	0.845	0.98
380_S	383_H	0.845	0.98
584_V	591_P	0.845	0.98
613_L	699_S	0.844	0.98
250_A	352_V	0.842	0.98
446_I	450_V	0.841	0.98
590_N	594_K	0.841	0.98
212_A	232_L	0.840	0.98
247_G	281_K	0.839	0.98
445_G	448_N	0.838	0.98
404_T	546_V	0.834	0.98
83_T	91_A	0.833	0.98
257_S	613_L	0.833	0.98
420_A	458_Y	0.832	0.98
633_D	703_K	0.832	0.98
589_Y	592_S	0.831	0.98
346_A	349_V	0.831	0.98
505_V	541_T	0.829	0.98
112_V	154_T	0.829	0.98
680_K	715_P	0.829	0.98
725_I	748_V	0.827	0.98
87_Q	91_A	0.826	0.98
508_V	550_M	0.826	0.98
461_G	495_A	0.825	0.98
181_T	239_P	0.824	0.98
288_H	319_M	0.823	0.98
139_G	192_M	0.822	0.98
671_A	748_V	0.822	0.98
601_R	638_A	0.822	0.98
147_A	203_V	0.816	0.98
109_A	317_M	0.815	0.98
445_G	578_G	0.810	0.98
664_K	667_G	0.810	0.98
736_Q	740_D	0.808	0.98
498_T	501_Q	0.806	0.98
276_D	279_G	0.805	0.98
653_V	758_K	0.804	0.98
153_M	352_V	0.804	0.98
77_V	81_F	0.802	0.98
233_F	273_V	0.799	0.98
233_F	241_K	0.798	0.98
671_A	674_Q	0.798	0.98
673_V	720_T	0.797	0.98
127_A	180_L	0.794	0.98
494_E	497_Q	0.790	0.98
507_A	545_L	0.788	0.98
204_M	356_M	0.788	0.98
344_D	347_R	0.788	0.98
344_D	348_H	0.786	0.98
83_T	87_Q	0.781	0.97
78_G	81_F	0.780	0.97
537_A	541_T	0.780	0.97
653_V	687_V	0.778	0.97
604_G	636_N	0.777	0.97
210_F	237_M	0.775	0.97
92_M	342_L	0.774	0.97
191_A	194_G	0.772	0.97
489_Q	492_I	0.771	0.97
162_S	597_M	0.771	0.97
496_V	538_L	0.771	0.97
578_G	582_A	0.770	0.97
653_V	673_V	0.769	0.97
703_K	757_V	0.769	0.97
98_E	106_L	0.767	0.97
392_R	579_N	0.766	0.97
542_G	565_D	0.765	0.97
600_P	632_F	0.762	0.97
506_V	585_L	0.761	0.97
409_K	449_A	0.761	0.97
84_V	87_Q	0.760	0.97
415_V	456_V	0.759	0.97
532_R	559_K	0.758	0.97
560_E	639_L	0.756	0.97
122_I	171_S	0.756	0.97
706_K	748_V	0.755	0.97
249_G	352_V	0.755	0.97
557_L	567_I	0.755	0.97
416_V	495_A	0.755	0.97
132_L	184_M	0.753	0.97
535_I	539_K	0.752	0.97
138_V	386_E	0.750	0.97
109_A	153_M	0.750	0.97
409_K	586_F	0.750	0.97
450_V	454_G	0.749	0.97
421_D	447_K	0.748	0.97
657_K	674_Q	0.747	0.97
416_V	538_L	0.746	0.97
539_K	563_Q	0.745	0.97
382_L	385_K	0.743	0.97
556_A	603_V	0.741	0.97
91_A	94_D	0.740	0.96
139_G	188_M	0.738	0.96
421_D	444_T	0.736	0.96
257_S	262_P	0.735	0.96
130_F	686_V	0.734	0.96
668_K	726_D	0.732	0.96
386_E	389_E	0.732	0.96
395_L	580_A	0.731	0.96
350_L	353_K	0.731	0.96
232_L	273_V	0.729	0.96
538_L	541_T	0.729	0.96
348_H	351_N	0.729	0.96
174_F	188_M	0.728	0.96
412_T	502_S	0.728	0.96
499_A	502_S	0.728	0.96
351_N	355_D	0.728	0.96
508_V	548_V	0.727	0.96
140_R	202_S	0.727	0.96
392_R	580_A	0.727	0.96
542_G	545_L	0.726	0.96
204_M	250_A	0.725	0.96
532_R	558_V	0.724	0.96
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631_Y	635_A	0.722	0.96
507_A	534_L	0.722	0.96
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134_A	137_T	0.720	0.96
154_T	203_V	0.719	0.96
698_M	732_F	0.718	0.96
493_D	537_A	0.717	0.96
142_S	192_M	0.716	0.96
162_S	170_A	0.716	0.96
77_V	80_I	0.716	0.96
291_I	315_I	0.716	0.96
211_A	263_A	0.714	0.96
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153_M	285_V	0.712	0.96
568_L	584_V	0.712	0.96
387_A	391_A	0.711	0.96
658_L	669_V	0.710	0.96
142_S	154_T	0.709	0.96
272_D	277_Q	0.707	0.95
187_T	190_E	0.707	0.95
753_D	757_V	0.707	0.95
283_I	317_M	0.706	0.95
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316_N	345_A	0.706	0.95
540_A	563_Q	0.706	0.95
419_L	550_M	0.705	0.95
271_K	275_R	0.705	0.95
281_K	351_N	0.703	0.95
693_D	742_E	0.703	0.95
324_Y	328_L	0.703	0.95
211_A	278_W	0.701	0.95
273_V	277_Q	0.701	0.95
625_N	701_P	0.700	0.95
421_D	460_K	0.699	0.95
83_T	88_D	0.699	0.95
669_V	725_I	0.698	0.95
275_R	351_N	0.697	0.95
679_G	716_G	0.696	0.95
660_A	669_V	0.694	0.95
633_D	754_S	0.694	0.95
712_T	715_P	0.694	0.95
590_N	649_T	0.694	0.95
90_R	94_D	0.693	0.95
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598_S	632_F	0.691	0.95
554_P	599_F	0.691	0.95
89_I	329_P	0.691	0.95
207_V	244_L	0.690	0.95
130_F	688_Q	0.690	0.95
309_V	312_K	0.688	0.95
125_G	571_W	0.688	0.95
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127_A	175_G	0.686	0.95
114_H	122_I	0.686	0.95
399_K	644_Y	0.685	0.95
416_V	499_A	0.684	0.95
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536_A	540_A	0.681	0.94
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228_S	624_P	0.679	0.94
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283_I	349_V	0.675	0.94
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561_D	567_I	0.671	0.94
341_E	345_A	0.670	0.94
518_E	521_S	0.668	0.94
189_V	248_S	0.668	0.94
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679_G	715_P	0.662	0.94
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463_N	466_S	0.662	0.94
342_L	346_A	0.661	0.94
689_M	707_G	0.660	0.93
445_G	579_N	0.660	0.93
224_T	260_G	0.659	0.93
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237_M	278_W	0.657	0.93
418_P	462_A	0.657	0.93
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273_V	278_W	0.650	0.93
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612_H	702_V	0.645	0.93
261_T	309_V	0.643	0.93
550_M	573_A	0.642	0.93
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632_F	636_N	0.641	0.92
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85_T	89_I	0.640	0.92
388_R	589_Y	0.640	0.92
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564_A	567_I	0.639	0.92
332_I	339_M	0.638	0.92
347_R	351_N	0.638	0.92
653_V	686_V	0.637	0.92
557_L	599_F	0.636	0.92
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535_I	564_A	0.634	0.92
440_V	448_N	0.634	0.92
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146_A	151_L	0.632	0.92
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211_A	232_L	0.631	0.92
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568_L	581_I	0.630	0.92
548_V	581_I	0.630	0.92
653_V	656_V	0.629	0.92
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532_R	560_E	0.629	0.92
526_T	603_V	0.629	0.92
159_V	181_T	0.629	0.92
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226_D	620_N	0.628	0.92
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459_A	462_A	0.628	0.92
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561_D	639_L	0.627	0.92
700_R	742_E	0.626	0.92
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713_L	721_V	0.626	0.92
311_L	341_E	0.626	0.92
407_L	585_L	0.625	0.92
311_L	332_I	0.625	0.92
415_V	506_V	0.622	0.91
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515_M	518_E	0.621	0.91
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495_A	538_L	0.621	0.91
264_T	315_I	0.620	0.91
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309_V	313_S	0.619	0.91
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88_D	92_M	0.615	0.91
691_L	725_I	0.615	0.91
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291_I	318_S	0.614	0.91
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451_G	455_K	0.611	0.91
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487_S	490_E	0.610	0.91
686_V	752_T	0.610	0.91
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231_R	625_N	0.609	0.90
495_A	534_L	0.609	0.90
414_A	459_A	0.608	0.90
556_A	559_K	0.608	0.90
232_L	269_L	0.607	0.90
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559_K	562_Q	0.606	0.90
233_F	237_M	0.605	0.90
640_Y	644_Y	0.605	0.90
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171_S	429_S	0.603	0.90
566_A	644_Y	0.603	0.90
524_D	603_V	0.602	0.90
690_Y	754_S	0.601	0.90
559_K	564_A	0.600	0.90
179_Y	706_K	0.600	0.90
647_S	651_F	0.600	0.90
120_F	138_V	0.600	0.90
659_S	663_M	0.599	0.90
132_L	707_G	0.598	0.90
234_N	739_Y	0.596	0.90
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217_E	220_K	0.594	0.89
142_S	188_M	0.594	0.89
242_A	728_E	0.593	0.89
219_G	617_R	0.593	0.89
707_G	721_V	0.591	0.89
354_Y	360_N	0.589	0.89
414_A	495_A	0.589	0.89
703_K	755_A	0.588	0.89
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695_T	746_F	0.587	0.89
251_V	280_F	0.587	0.89
488_P	491_M	0.587	0.89
451_G	456_V	0.587	0.89
395_L	593_G	0.586	0.89
663_M	667_G	0.586	0.89
419_L	510_G	0.585	0.89
685_T	758_K	0.585	0.89
180_L	596_P	0.585	0.89
128_S	571_W	0.584	0.89
346_A	350_L	0.583	0.88
350_L	354_Y	0.583	0.88
229_P	259_N	0.583	0.88
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184_M	708_F	0.580	0.88
659_S	672_S	0.579	0.88
413_I	454_G	0.579	0.88
595_L	599_F	0.579	0.88
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730_L	741_A	0.579	0.88
130_F	180_L	0.578	0.88
124_L	571_W	0.578	0.88
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340_A	344_D	0.574	0.88
666_D	727_I	0.574	0.88
558_V	562_Q	0.573	0.88
241_K	739_Y	0.572	0.88
193_Q	249_G	0.571	0.87
527_I	555_L	0.570	0.87
415_V	458_Y	0.570	0.87
357_G	360_N	0.570	0.87
687_V	721_V	0.570	0.87
548_V	568_L	0.570	0.87
447_K	456_V	0.567	0.87
607_P	632_F	0.567	0.87
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295_I	331_L	0.565	0.87
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727_I	731_K	0.563	0.87
427_M	439_S	0.563	0.87
505_V	508_V	0.562	0.87
727_I	741_A	0.560	0.86
218_G	612_H	0.560	0.86
139_G	189_V	0.559	0.86
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560_E	640_Y	0.557	0.86
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558_V	601_R	0.556	0.86
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525_I	554_P	0.555	0.86
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386_E	390_V	0.555	0.86
231_R	235_D	0.555	0.86
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413_I	456_V	0.554	0.86
429_S	433_A	0.551	0.86
362_P	365_H	0.550	0.85
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649_T	681_R	0.548	0.85
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311_L	337_V	0.548	0.85
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493_D	496_V	0.546	0.85
285_V	317_M	0.545	0.85
723_F	729_A	0.545	0.85
545_L	564_A	0.544	0.85
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332_I	341_E	0.544	0.85
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412_T	454_G	0.544	0.85
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275_R	345_A	0.542	0.85
395_L	581_I	0.542	0.85
80_I	104_I	0.542	0.85
192_M	203_V	0.541	0.85
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166_R	525_I	0.540	0.84
178_T	182_S	0.540	0.84
545_L	565_D	0.540	0.84
291_I	310_A	0.540	0.84
294_L	325_S	0.538	0.84
644_Y	758_K	0.538	0.84
261_T	265_S	0.538	0.84
671_A	725_I	0.537	0.84
420_A	508_V	0.537	0.84
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419_L	508_V	0.535	0.84
262_P	292_K	0.535	0.84
83_T	86_R	0.535	0.84
269_L	273_V	0.535	0.84
385_K	388_R	0.535	0.84
114_H	123_S	0.535	0.84
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541_T	545_L	0.533	0.84
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226_D	259_N	0.532	0.84
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141_V	390_V	0.531	0.83
385_K	392_R	0.531	0.83
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696_A	746_F	0.528	0.83
238_P	248_S	0.528	0.83
654_S	673_V	0.528	0.83
428_G	431_S	0.527	0.83
511_E	572_F	0.527	0.83
747_N	750_I	0.527	0.83
275_R	341_E	0.527	0.83
688_Q	754_S	0.526	0.83
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331_L	334_S	0.525	0.83
698_M	742_E	0.525	0.83
316_N	344_D	0.525	0.83
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590_N	684_A	0.524	0.83
449_A	582_A	0.524	0.83
109_A	319_M	0.523	0.82
131_N	389_E	0.522	0.82
509_V	527_I	0.521	0.82
689_M	729_A	0.520	0.82
698_M	735_Q	0.520	0.82
667_G	726_D	0.519	0.82
118_T	383_H	0.519	0.82
691_L	730_L	0.519	0.82
631_Y	634_E	0.519	0.82
337_V	342_L	0.518	0.82
611_S	704_Q	0.518	0.82
556_A	640_Y	0.518	0.82
528_P	531_Q	0.518	0.82
440_V	444_T	0.516	0.82
289_G	320_S	0.516	0.82
500_K	541_T	0.513	0.81
156_A	188_M	0.513	0.81
499_A	541_T	0.512	0.81
656_V	673_V	0.512	0.81
654_S	759_K	0.512	0.81
438_Q	576_E	0.510	0.81
459_A	495_A	0.510	0.81
551_N	555_L	0.510	0.81
590_N	682_E	0.510	0.81
499_A	537_A	0.509	0.81
155_W	320_S	0.509	0.81
219_G	222_Y	0.509	0.81
174_F	181_T	0.508	0.81
352_V	355_D	0.508	0.81
523_T	602_S	0.508	0.81
399_K	646_L	0.508	0.81
709_E	722_S	0.508	0.81
337_V	341_E	0.507	0.81
401_R	404_T	0.507	0.81
663_M	727_I	0.507	0.81
230_Q	732_F	0.507	0.81
75_G	78_G	0.507	0.81
235_D	625_N	0.506	0.80
714_K	719_Q	0.506	0.80
322_E	325_S	0.506	0.80
603_V	606_I	0.506	0.80
107_F	353_K	0.505	0.80
361_D	364_S	0.505	0.80
459_A	491_M	0.504	0.80
253_V	271_K	0.503	0.80
634_E	702_V	0.503	0.80
752_T	755_A	0.503	0.80
143_A	203_V	0.502	0.80
332_I	335_G	0.501	0.80
560_E	564_A	0.501	0.80
104_I	350_L	0.501	0.80
155_W	285_V	0.501	0.80
418_P	531_Q	0.501	0.80
123_S	156_A	0.501	0.80
230_Q	259_N	0.501	0.80
291_I	324_Y	0.500	0.80
408_K	586_F	0.500	0.80

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3u48A	2	0.9516	100	0.195	Contact Map
3abzA	3	0.8654	100	0.197	Contact Map
4i3gA	1	0.8667	100	0.197	Contact Map
2x41A	1	0.8627	100	0.218	Contact Map
3zyzA	1	0.8562	100	0.225	Contact Map
4iibA	2	0.8824	100	0.238	Contact Map
4d0jA	4	0.8719	100	0.24	Contact Map
3rrxA	1	0.7529	100	0.324	Contact Map
3wliA	1	0.7399	100	0.381	Contact Map
3bmxA	1	0.7085	100	0.458	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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