GREMLIN Database
YEHC - Probable fimbrial chaperone YehC
UniProt: P33342 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG11989
Length: 239 (214)
Sequences: 2877 (2194)
Seq/√Len: 150.0

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
69_I149_L3.2351.00
187_T204_M3.1801.00
185_W206_A3.0701.00
179_K210_S2.9921.00
118_I204_M2.9841.00
45_P48_N2.9751.00
206_A209_E2.8911.00
115_K208_L2.8681.00
168_L179_K2.8171.00
37_I147_I2.8101.00
177_V212_S2.6661.00
169_V178_I2.6571.00
111_L119_F2.5601.00
42_I51_V2.5291.00
177_V210_S2.5061.00
63_S125_D2.4901.00
150_F204_M2.4151.00
47_E154_A2.4121.00
42_I104_I2.3911.00
162_A165_K2.3621.00
42_I121_L2.3561.00
178_I213_V2.2371.00
60_N97_N2.2261.00
229_D235_I2.1971.00
150_F185_W2.1371.00
62_S95_G2.0431.00
170_N177_V2.0351.00
70_D146_R2.0281.00
68_W122_N1.9911.00
124_L144_Q1.9381.00
163_T186_V1.8991.00
167_L178_I1.8751.00
45_P51_V1.8521.00
167_L186_V1.8091.00
85_F104_I1.8061.00
112_P117_S1.8021.00
62_S93_K1.7921.00
67_A102_V1.7791.00
156_I184_N1.7651.00
37_I123_V1.6991.00
166_K182_S1.6981.00
87_L102_V1.6711.00
70_D122_N1.6101.00
95_G98_S1.6091.00
69_I83_V1.5971.00
122_N146_R1.5941.00
118_I150_F1.5921.00
186_V227_I1.5501.00
163_T227_I1.5391.00
190_D226_T1.5341.00
229_D233_N1.4891.00
172_S177_V1.4751.00
53_V121_L1.4521.00
46_A113_T1.4391.00
170_N179_K1.4301.00
65_L92_A1.4131.00
175_G212_S1.3911.00
54_Q99_G1.3841.00
205_I211_Q1.3841.00
112_P115_K1.3781.00
167_L188_I1.3451.00
159_V162_A1.3381.00
118_I187_T1.3351.00
85_F149_L1.3311.00
44_Y51_V1.3131.00
87_L104_I1.3031.00
183_A208_L1.2601.00
50_E103_K1.2531.00
169_V225_L1.2451.00
175_G214_N1.2381.00
192_K224_H1.2281.00
59_G125_D1.2271.00
106_I109_N1.2091.00
42_I147_I1.1891.00
176_L215_V1.1791.00
192_K197_K1.1731.00
102_V121_L1.1431.00
37_I53_V1.1431.00
55_L94_I1.1260.99
187_T227_I1.1230.99
46_A154_A1.1220.99
106_I110_K1.1170.99
104_I149_L1.1160.99
227_I235_I1.0910.99
36_V39_G1.0770.99
106_I151_Y1.0710.99
164_F225_L1.0700.99
121_L149_L1.0590.99
189_S234_Y1.0590.99
92_A100_Q1.0590.99
71_D81_I1.0560.99
68_W146_R1.0460.99
16_M21_S1.0430.99
130_S138_A1.0400.99
34_G125_D1.0270.99
39_G53_V1.0190.99
35_I94_I1.0190.99
125_D143_M1.0180.99
46_A151_Y1.0130.99
120_Y146_R1.0110.99
38_Y54_Q1.0100.99
130_S140_K1.0100.99
188_I205_I1.0090.99
44_Y105_K1.0080.99
17_K25_F1.0020.99
56_M99_G1.0000.99
166_K181_D0.9980.99
100_Q124_L0.9980.99
70_D74_T0.9900.99
71_D79_E0.9860.99
68_W124_L0.9860.99
158_P184_N0.9710.98
35_I65_L0.9690.98
164_F186_V0.9580.98
172_S212_S0.9430.98
42_I53_V0.9380.98
172_S175_G0.9340.98
171_R174_N0.9190.98
102_V123_V0.9130.98
41_R152_R0.9090.98
94_I99_G0.9070.98
21_S24_I0.9060.98
142_A169_V0.9040.98
19_L22_L0.9020.98
188_I227_I0.9010.98
116_E152_R0.8900.97
37_I55_L0.8890.97
226_T234_Y0.8790.97
194_N221_N0.8780.97
148_K228_I0.8730.97
70_D120_Y0.8700.97
44_Y85_F0.8690.97
28_V32_H0.8680.97
87_L121_L0.8620.97
179_K208_L0.8600.97
171_R219_N0.8490.96
69_I87_L0.8460.96
120_Y124_L0.8370.96
38_Y99_G0.8370.96
188_I233_N0.8330.96
94_I100_Q0.8320.96
100_Q125_D0.8300.96
114_N208_L0.8270.96
16_M23_L0.8190.96
131_P134_E0.8180.96
67_A87_L0.8180.96
59_G63_S0.8170.96
20_L23_L0.8170.96
196_V218_N0.8120.95
169_V191_V0.8060.95
17_K20_L0.7970.95
118_I185_W0.7880.95
72_G120_Y0.7870.95
92_A102_V0.7860.95
155_G158_P0.7830.94
185_W207_P0.7800.94
34_G58_Q0.7750.94
193_A223_W0.7740.94
168_L181_D0.7700.94
189_S228_I0.7680.94
187_T202_T0.7670.94
119_F151_Y0.7660.94
114_N152_R0.7650.94
122_N144_Q0.7650.94
41_R148_K0.7600.94
44_Y106_I0.7550.93
67_A123_V0.7550.93
162_A166_K0.7530.93
43_I152_R0.7510.93
55_L65_L0.7490.93
191_V213_V0.7470.93
164_F227_I0.7440.93
104_I121_L0.7400.93
39_G42_I0.7390.93
122_N148_K0.7370.92
158_P162_A0.7340.92
123_V147_I0.7280.92
176_L191_V0.7270.92
113_T155_G0.7240.92
71_D83_V0.7230.92
192_K195_N0.7150.91
94_I98_S0.7130.91
36_V58_Q0.7100.91
71_D82_Q0.7090.91
169_V176_L0.7090.91
63_S67_A0.7080.91
54_Q91_V0.7070.91
120_Y148_K0.7050.91
16_M19_L0.7040.91
137_N140_K0.7030.91
34_G63_S0.7000.90
158_P163_T0.6980.90
69_I126_I0.6950.90
63_S124_L0.6940.90
73_D80_K0.6940.90
16_M28_V0.6930.90
36_V145_N0.6920.90
66_Q124_L0.6910.90
190_D197_K0.6830.89
18_G21_S0.6810.89
21_S222_N0.6760.89
19_L172_S0.6750.89
62_S128_P0.6700.88
65_L94_I0.6660.88
202_T213_V0.6630.88
115_K153_P0.6590.88
160_N164_F0.6570.87
117_S151_Y0.6560.87
22_L25_F0.6560.87
22_L29_L0.6550.87
159_V163_T0.6530.87
58_Q128_P0.6530.87
41_R153_P0.6510.87
45_P150_F0.6480.87
191_V215_V0.6440.86
41_R230_D0.6410.86
167_L227_I0.6410.86
24_I199_N0.6390.86
148_K152_R0.6380.86
148_K187_T0.6360.86
171_R175_G0.6330.85
72_G118_I0.6310.85
178_I205_I0.6300.85
198_V218_N0.6220.84
215_V218_N0.6220.84
90_P126_I0.6140.84
91_V99_G0.6120.84
23_L28_V0.6110.83
125_D142_A0.6090.83
120_Y187_T0.6080.83
164_F181_D0.6080.83
85_F151_Y0.6070.83
126_I143_M0.6070.83
55_L128_P0.6060.83
159_V166_K0.6050.83
192_K226_T0.6030.83
120_Y123_V0.6020.83
29_L32_H0.5990.82
103_K127_P0.5980.82
64_L184_N0.5970.82
23_L161_K0.5930.82
49_K60_N0.5920.81
70_D141_F0.5910.81
67_A100_Q0.5900.81
44_Y48_N0.5880.81
16_M29_L0.5880.81
64_L124_L0.5880.81
21_S32_H0.5870.81
164_F182_S0.5810.80
143_M202_T0.5770.80
18_G26_S0.5730.79
44_Y49_K0.5730.79
40_T152_R0.5700.79
22_L30_P0.5670.79
185_W209_E0.5650.78
39_G124_L0.5620.78
52_M141_F0.5600.78
67_A92_A0.5590.78
27_M31_A0.5580.78
125_D187_T0.5570.77
127_P142_A0.5570.77
144_Q169_V0.5560.77
32_H176_L0.5560.77
72_G146_R0.5560.77
125_D144_Q0.5550.77
196_V200_Y0.5550.77
17_K22_L0.5530.77
35_I63_S0.5510.77
193_A222_N0.5510.77
152_R207_P0.5490.76
114_N117_S0.5490.76
59_G124_L0.5470.76
116_E230_D0.5440.76
69_I119_F0.5420.75
23_L27_M0.5410.75
211_Q214_N0.5410.75
156_I183_A0.5400.75
175_G215_V0.5380.75
225_L235_I0.5370.75
203_I213_V0.5370.75
37_I58_Q0.5360.75
164_F167_L0.5350.75
85_F117_S0.5340.74
37_I64_L0.5330.74
153_P207_P0.5330.74
48_N109_N0.5320.74
19_L23_L0.5320.74
98_S225_L0.5310.74
195_N217_S0.5290.74
131_P168_L0.5280.74
152_R184_N0.5260.73
18_G212_S0.5260.73
113_T154_A0.5230.73
192_K196_V0.5230.73
68_W145_N0.5210.73
51_V149_L0.5200.72
54_Q141_F0.5200.72
26_S30_P0.5200.72
37_I145_N0.5190.72
205_I209_E0.5190.72
169_V223_W0.5170.72
28_V31_A0.5170.72
129_N140_K0.5160.72
64_L90_P0.5150.72
188_I225_L0.5130.71
161_K165_K0.5130.71
174_N218_N0.5120.71
17_K24_I0.5120.71
27_M170_N0.5090.71
139_L146_R0.5090.71
176_L223_W0.5080.71
29_L170_N0.5080.71
53_V104_I0.5080.71
18_G30_P0.5070.71
54_Q124_L0.5060.70
152_R156_I0.5060.70
58_Q63_S0.5060.70
176_L212_S0.5050.70
154_A157_A0.5030.70
142_A146_R0.5020.70
64_L125_D0.5000.70
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2co7B 1 0.8117 100 0.185 Contact Map
1klfA 1 0.8326 100 0.189 Contact Map
1l4iA 2 0.7782 100 0.194 Contact Map
3q48A 1 0.7866 100 0.195 Contact Map
2xg5A 1 0.8285 100 0.213 Contact Map
4djmA 1 0.8243 100 0.219 Contact Map
3gfuC 1 0.8075 100 0.219 Contact Map
4ay0A 2 0.7782 100 0.226 Contact Map
4ncdA 2 0.795 100 0.271 Contact Map
1mspA 3 0.4812 95.3 0.902 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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