LLDP - ECOLI - GREMLIN Contacts

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LLDP - L-lactate permease

UniProt:	P33231	Sequences: MNLWQQNYDPAGNIWLSSLIASLPILFFFFALIKLKLKGYVAASWTVAIALAVALLFYKMPVANALASVVYGFFYGLWPIAWIIIAAVFVYKISVKTGQFDIIRSSILSITPDQRLQMLIVGFCFGAFLEGAAGFGAPVAITAALLVGLGFKPLYAAGLCLIVNTAPVAFGAMGIPILVAGQVTGIDSFEIGQMVGRQLPFMTIIVLFWIMAIMDGWRGIKETWPAVVVAGGSFAIAQYLSSNFIGPELPDIISSLVSLLCLTLFLKRWQPVRVFRFGDLGASQVDMTLAHTGYTAGQVLRAWTPFLFLTATVTLWSIPPFKALFASGGALYEWVINIPVPYLDKLVARMPPVVSEATAYAAVFKFDWFSATGTAILFAALLSIVWLKMKPSDAISTFGSTLKELALPIYSIGMVLAFAFISNYSGLSSTLALALAHTGHAFTFFSPFLGWLGVFLTGSDTSSNALFAALQATAAQQIGVSDLLLVAANTTGGVTGKMISPQSIAIACAAVGLVGKESDLFRFTVKHSLIFTCIVGVITTLQAYVLTWMIP	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG11961
Length:	551 (498)
Sequences:	1579 (999)
Seq/√Len:	44.8

ECOLI - LLDP GLCA
BACSU - LUTP LCTP
HALSA - Q9HHI2
SULSO - Q7LX72

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
516_K	519_D	6.705	1.00
52_A	56_L	5.054	1.00
27_F	49_I	4.784	1.00
488_A	539_T	4.547	1.00
442_F	446_S	4.496	1.00
264_L	268_R	4.128	1.00
222_E	273_R	4.017	1.00
237_A	257_V	3.911	1.00
55_L	65_A	3.902	1.00
403_K	406_A	3.885	1.00
381_L	385_V	3.536	1.00
51_L	65_A	3.507	1.00
229_V	265_F	3.501	1.00
448_F	532_T	3.298	1.00
399_G	403_K	3.213	1.00
30_F	35_L	3.161	1.00
532_T	536_G	3.152	1.00
180_A	468_A	3.152	1.00
97_T	389_M	3.140	1.00
51_L	421_I	3.095	1.00
111_T	116_L	3.071	1.00
124_C	258_S	2.984	1.00
96_K	400_S	2.964	1.00
47_V	69_V	2.841	1.00
92_K	404_E	2.809	1.00
27_F	31_A	2.809	1.00
197_R	243_N	2.782	1.00
480_V	485_L	2.751	1.00
73_F	413_G	2.671	1.00
312_T	378_F	2.639	1.00
215_D	219_G	2.637	1.00
383_S	387_L	2.518	1.00
20_I	57_F	2.485	1.00
53_V	57_F	2.476	1.00
96_K	393_D	2.433	1.00
37_L	41_V	2.372	1.00
379_A	383_S	2.324	1.00
304_T	386_W	2.215	1.00
297_G	301_R	2.207	1.00
392_S	396_S	2.193	1.00
537_V	541_L	2.189	1.00
395_I	399_G	2.181	1.00
468_A	486_V	2.159	1.00
236_I	240_L	2.154	1.00
233_S	261_C	2.113	1.00
157_A	507_A	2.111	1.00
48_A	52_A	2.109	1.00
448_F	536_G	2.094	1.00
147_V	511_V	2.086	0.99
472_A	486_V	2.076	0.99
70_V	354_V	2.076	0.99
300_L	304_T	2.075	0.99
294_Y	298_Q	2.072	0.99
533_C	537_V	2.062	0.99
301_R	388_K	2.061	0.99
384_I	394_A	2.025	0.99
316_W	375_A	1.977	0.99
180_A	486_V	1.974	0.99
253_I	257_V	1.963	0.99
390_K	393_D	1.953	0.99
422_S	428_S	1.946	0.99
101_D	104_R	1.904	0.99
162_I	213_I	1.874	0.99
321_F	324_L	1.862	0.99
168_V	460_D	1.838	0.99
96_K	396_S	1.833	0.99
194_M	483_L	1.828	0.99
44_S	414_M	1.809	0.99
18_S	434_A	1.796	0.98
31_A	45_W	1.793	0.98
233_S	258_S	1.770	0.98
42_A	128_F	1.746	0.98
30_F	34_K	1.739	0.98
187_D	190_E	1.738	0.98
178_L	247_P	1.725	0.98
391_P	395_I	1.725	0.98
300_L	307_L	1.709	0.98
240_L	244_F	1.698	0.98
324_L	327_S	1.697	0.98
260_L	264_L	1.695	0.98
90_V	380_A	1.695	0.98
461_T	496_G	1.689	0.98
81_A	409_I	1.680	0.98
31_A	37_L	1.678	0.98
181_G	186_I	1.674	0.98
241_S	253_I	1.667	0.97
233_S	257_V	1.662	0.97
497_K	503_S	1.656	0.97
239_Y	244_F	1.647	0.97
38_K	42_A	1.636	0.97
207_L	211_M	1.634	0.97
180_A	191_I	1.626	0.97
295_T	298_Q	1.612	0.97
177_I	195_V	1.600	0.97
118_M	159_L	1.599	0.97
322_K	326_A	1.589	0.97
106_S	303_W	1.589	0.97
225_P	269_W	1.589	0.97
451_W	528_S	1.559	0.96
116_L	226_A	1.550	0.96
181_G	188_S	1.536	0.96
114_Q	277_F	1.536	0.96
318_I	321_F	1.536	0.96
460_D	493_G	1.524	0.96
196_G	242_S	1.521	0.96
298_Q	301_R	1.493	0.95
105_S	294_Y	1.477	0.95
45_W	48_A	1.473	0.95
126_G	163_V	1.472	0.95
237_A	254_S	1.464	0.95
205_I	208_F	1.457	0.94
129_L	137_A	1.452	0.94
212_A	220_I	1.446	0.94
230_A	262_L	1.444	0.94
68_S	71_Y	1.441	0.94
92_K	401_T	1.423	0.94
122_G	126_G	1.423	0.94
165_T	498_M	1.422	0.94
119_L	230_A	1.415	0.93
265_F	269_W	1.402	0.93
89_F	380_A	1.401	0.93
504_I	521_F	1.392	0.93
540_T	544_Y	1.390	0.93
71_Y	424_Y	1.389	0.93
225_P	271_P	1.361	0.92
304_T	307_L	1.339	0.91
211_M	223_T	1.337	0.91
158_G	523_F	1.330	0.91
378_F	382_L	1.329	0.91
224_W	227_V	1.325	0.91
90_V	309_L	1.319	0.91
508_C	520_L	1.310	0.91
186_I	483_L	1.303	0.90
193_Q	239_Y	1.301	0.90
158_G	520_L	1.300	0.90
389_M	393_D	1.293	0.90
495_T	531_F	1.293	0.90
20_I	23_L	1.292	0.90
172_A	175_I	1.291	0.90
136_G	171_G	1.289	0.90
122_G	163_V	1.287	0.90
197_R	239_Y	1.284	0.90
455_F	524_T	1.283	0.90
66_L	69_V	1.282	0.90
196_G	200_P	1.271	0.89
441_A	444_F	1.260	0.89
183_V	465_A	1.256	0.89
19_L	23_L	1.255	0.89
198_Q	542_Q	1.253	0.88
195_V	491_T	1.247	0.88
226_A	265_F	1.245	0.88
526_K	530_I	1.244	0.88
55_L	62_V	1.239	0.88
147_V	513_L	1.235	0.88
46_T	418_F	1.232	0.88
229_V	261_C	1.224	0.87
468_A	472_A	1.224	0.87
135_F	459_S	1.222	0.87
114_Q	151_F	1.222	0.87
209_W	527_H	1.212	0.87
237_A	253_I	1.208	0.87
83_I	172_A	1.202	0.86
23_L	49_I	1.195	0.86
137_A	518_S	1.195	0.86
352_P	355_S	1.191	0.86
315_L	321_F	1.180	0.85
97_T	387_L	1.170	0.85
444_F	533_C	1.166	0.85
114_Q	276_R	1.165	0.84
367_D	370_S	1.163	0.84
95_V	101_D	1.161	0.84
119_L	227_V	1.153	0.84
239_Y	243_N	1.146	0.84
127_A	167_P	1.145	0.83
117_Q	149_L	1.143	0.83
97_T	173_M	1.142	0.83
214_M	219_G	1.140	0.83
312_T	379_A	1.132	0.83
89_F	394_A	1.131	0.83
121_V	142_T	1.124	0.82
56_L	62_V	1.123	0.82
44_S	410_Y	1.123	0.82
68_S	424_Y	1.122	0.82
196_G	243_N	1.121	0.82
169_A	460_D	1.119	0.82
175_I	178_L	1.115	0.82
438_T	441_A	1.113	0.82
75_Y	420_F	1.111	0.82
198_Q	491_T	1.111	0.82
449_L	470_L	1.110	0.81
135_F	461_T	1.107	0.81
232_G	381_L	1.105	0.81
215_D	220_I	1.104	0.81
154_L	523_F	1.098	0.81
392_S	533_C	1.098	0.81
92_K	400_S	1.097	0.81
404_E	408_P	1.095	0.81
124_C	259_L	1.094	0.81
179_V	182_Q	1.093	0.80
86_A	398_F	1.089	0.80
56_L	59_K	1.088	0.80
154_L	307_L	1.086	0.80
74_F	364_F	1.082	0.80
135_F	172_A	1.077	0.79
188_S	192_G	1.077	0.79
499_I	525_V	1.074	0.79
117_Q	151_F	1.074	0.79
47_V	133_A	1.064	0.79
244_F	481_S	1.064	0.79
128_F	310_T	1.063	0.79
234_F	251_D	1.059	0.78
144_A	434_A	1.058	0.78
444_F	540_T	1.049	0.78
308_F	379_A	1.049	0.78
179_V	431_L	1.044	0.77
429_S	473_T	1.031	0.76
191_I	486_V	1.029	0.76
93_I	397_T	1.029	0.76
53_V	58_Y	1.024	0.76
67_A	70_V	1.022	0.76
51_L	55_L	1.021	0.76
82_W	374_T	1.017	0.75
416_L	470_L	1.016	0.75
352_P	361_A	1.015	0.75
128_F	132_A	1.013	0.75
71_Y	420_F	1.013	0.75
27_F	46_T	1.011	0.75
526_K	529_L	1.011	0.75
102_I	294_Y	1.006	0.75
397_T	400_S	1.001	0.74
114_Q	275_F	1.001	0.74
165_T	460_D	0.990	0.73
204_I	231_G	0.985	0.73
533_C	536_G	0.983	0.73
422_S	427_L	0.979	0.73
69_V	421_I	0.978	0.73
519_D	522_R	0.976	0.72
83_I	175_I	0.975	0.72
453_G	463_S	0.974	0.72
318_I	325_F	0.972	0.72
207_L	210_I	0.962	0.71
73_F	417_A	0.962	0.71
492_G	496_G	0.959	0.71
301_R	304_T	0.956	0.71
119_L	262_L	0.955	0.71
28_F	46_T	0.951	0.70
497_K	502_Q	0.950	0.70
317_S	370_S	0.949	0.70
116_L	223_T	0.948	0.70
464_N	490_T	0.945	0.70
321_F	325_F	0.943	0.70
247_P	262_L	0.942	0.70
121_V	149_L	0.942	0.70
58_Y	430_T	0.941	0.70
179_V	465_A	0.941	0.70
450_G	467_F	0.940	0.69
368_W	371_A	0.939	0.69
80_I	135_F	0.938	0.69
475_A	498_M	0.937	0.69
73_F	77_L	0.937	0.69
174_G	246_G	0.935	0.69
384_I	388_K	0.934	0.69
380_A	394_A	0.934	0.69
98_G	156_A	0.931	0.69
200_P	203_T	0.929	0.69
31_A	306_F	0.928	0.68
112_P	274_V	0.926	0.68
227_V	231_G	0.926	0.68
238_Q	460_D	0.926	0.68
233_S	237_A	0.924	0.68
400_S	403_K	0.922	0.68
167_P	460_D	0.921	0.68
81_A	412_I	0.919	0.68
240_L	534_I	0.913	0.67
398_F	402_L	0.913	0.67
168_V	498_M	0.911	0.67
127_A	163_V	0.908	0.67
248_E	317_S	0.907	0.67
70_V	353_V	0.899	0.66
506_I	527_H	0.899	0.66
218_R	273_R	0.898	0.66
443_T	536_G	0.897	0.66
320_P	324_L	0.896	0.66
423_N	462_S	0.892	0.65
165_T	494_V	0.889	0.65
169_A	494_V	0.886	0.65
478_I	485_L	0.882	0.65
432_A	473_T	0.880	0.64
227_V	232_G	0.876	0.64
225_P	265_F	0.866	0.63
85_I	402_L	0.866	0.63
46_T	88_V	0.866	0.63
36_K	519_D	0.865	0.63
122_G	210_I	0.864	0.63
65_A	74_F	0.860	0.63
304_T	308_F	0.854	0.62
55_L	260_L	0.854	0.62
443_T	478_I	0.852	0.62
264_L	291_H	0.839	0.61
52_A	59_K	0.838	0.61
442_F	478_I	0.834	0.60
469_A	472_A	0.833	0.60
307_L	533_C	0.833	0.60
350_M	353_V	0.832	0.60
460_D	491_T	0.832	0.60
16_L	57_F	0.831	0.60
433_L	477_Q	0.831	0.60
308_F	386_W	0.830	0.60
292_T	296_A	0.830	0.60
37_L	45_W	0.830	0.60
17_S	57_F	0.828	0.60
497_K	506_I	0.828	0.60
489_N	497_K	0.827	0.59
247_P	250_P	0.824	0.59
130_E	171_G	0.822	0.59
128_F	247_P	0.822	0.59
533_C	541_L	0.822	0.59
448_F	529_L	0.819	0.59
92_K	397_T	0.818	0.59
116_L	477_Q	0.818	0.59
232_G	236_I	0.818	0.59
307_L	311_A	0.817	0.59
500_S	505_A	0.816	0.58
180_A	465_A	0.815	0.58
275_F	278_G	0.814	0.58
32_L	36_K	0.811	0.58
475_A	480_V	0.809	0.58
202_M	435_L	0.807	0.58
241_S	257_V	0.807	0.58
128_F	309_L	0.805	0.57
80_I	170_F	0.805	0.57
260_L	307_L	0.802	0.57
267_K	293_G	0.802	0.57
69_V	417_A	0.802	0.57
218_R	222_E	0.801	0.57
529_L	533_C	0.800	0.57
123_F	250_P	0.799	0.57
313_V	316_W	0.797	0.57
28_F	145_L	0.796	0.57
385_V	391_P	0.795	0.56
383_S	389_M	0.795	0.56
68_S	448_F	0.793	0.56
163_V	167_P	0.793	0.56
128_F	504_I	0.792	0.56
146_L	207_L	0.792	0.56
172_A	459_S	0.791	0.56
218_R	537_V	0.785	0.56
309_L	374_T	0.783	0.55
103_I	303_W	0.783	0.55
51_L	66_L	0.782	0.55
260_L	272_V	0.779	0.55
129_L	419_A	0.778	0.55
201_F	221_K	0.774	0.54
238_Q	494_V	0.773	0.54
97_T	486_V	0.772	0.54
45_W	469_A	0.772	0.54
22_S	431_L	0.772	0.54
129_L	141_I	0.769	0.54
192_G	247_P	0.768	0.54
120_I	266_L	0.768	0.54
157_A	470_L	0.766	0.54
308_F	382_L	0.766	0.54
451_W	532_T	0.764	0.53
290_A	361_A	0.762	0.53
439_G	445_F	0.760	0.53
261_C	402_L	0.760	0.53
132_A	172_A	0.758	0.53
166_A	251_D	0.758	0.53
107_I	496_G	0.757	0.53
438_T	445_F	0.757	0.53
20_I	53_V	0.756	0.53
25_I	131_G	0.754	0.53
22_S	26_L	0.749	0.52
61_P	224_W	0.748	0.52
86_A	180_A	0.748	0.52
410_Y	414_M	0.746	0.52
102_I	298_Q	0.745	0.52
49_I	434_A	0.745	0.52
123_F	254_S	0.744	0.52
177_I	490_T	0.743	0.51
33_I	118_M	0.742	0.51
172_A	177_I	0.741	0.51
207_L	489_N	0.740	0.51
218_R	386_W	0.739	0.51
151_F	443_T	0.738	0.51
76_G	411_S	0.736	0.51
534_I	538_I	0.736	0.51
494_V	502_Q	0.736	0.51
431_L	456_L	0.735	0.51
88_V	103_I	0.734	0.51
31_A	233_S	0.733	0.50
355_S	378_F	0.731	0.50
134_G	171_G	0.729	0.50
54_A	421_I	0.729	0.50
49_I	52_A	0.727	0.50
142_T	254_S	0.726	0.50
244_F	268_R	0.726	0.50
198_Q	201_F	0.726	0.50
26_L	30_F	0.725	0.50
137_A	461_T	0.723	0.50
149_L	487_A	0.723	0.50
33_I	518_S	0.722	0.49
177_I	464_N	0.721	0.49
289_L	292_T	0.721	0.49
59_K	381_L	0.720	0.49
86_A	376_I	0.719	0.49
130_E	136_G	0.719	0.49
313_V	376_I	0.717	0.49
60_M	425_S	0.717	0.49
161_L	498_M	0.716	0.49
257_V	261_C	0.716	0.49
66_L	537_V	0.715	0.49
133_A	137_A	0.714	0.49
122_G	231_G	0.714	0.49
117_Q	408_P	0.714	0.49
194_M	197_R	0.714	0.49
208_F	224_W	0.713	0.49
128_F	376_I	0.713	0.49
492_G	499_I	0.712	0.48
390_K	476_Q	0.711	0.48
128_F	160_C	0.707	0.48
192_G	200_P	0.705	0.48
295_T	533_C	0.705	0.48
393_D	396_S	0.704	0.48
169_A	238_Q	0.704	0.48
191_I	484_L	0.703	0.48
442_F	524_T	0.703	0.48
391_P	396_S	0.702	0.47
245_I	253_I	0.701	0.47
169_A	177_I	0.698	0.47
104_R	145_L	0.698	0.47
179_V	456_L	0.697	0.47
501_P	505_A	0.696	0.47
38_K	41_V	0.696	0.47
217_W	220_I	0.696	0.47
173_M	317_S	0.695	0.47
118_M	445_F	0.695	0.47
215_D	221_K	0.695	0.47
198_Q	231_G	0.692	0.47
114_Q	278_G	0.692	0.47
519_D	523_F	0.691	0.46
290_A	311_A	0.690	0.46
391_P	444_F	0.690	0.46
169_A	490_T	0.690	0.46
191_I	472_A	0.689	0.46
403_K	533_C	0.687	0.46
47_V	51_L	0.686	0.46
525_V	530_I	0.685	0.46
64_N	68_S	0.685	0.46
95_V	104_R	0.684	0.46
197_R	235_A	0.683	0.46
165_T	168_V	0.682	0.46
83_I	90_V	0.682	0.46
170_F	250_P	0.682	0.46
292_T	391_P	0.677	0.45
233_S	499_I	0.676	0.45
200_P	211_M	0.674	0.45
490_T	494_V	0.673	0.45
306_F	376_I	0.672	0.45
407_L	410_Y	0.671	0.44
131_G	303_W	0.670	0.44
185_G	417_A	0.670	0.44
411_S	493_G	0.669	0.44
350_M	444_F	0.669	0.44
460_D	497_K	0.668	0.44
327_S	382_L	0.668	0.44
156_A	303_W	0.667	0.44
254_S	308_F	0.665	0.44
222_E	225_P	0.663	0.44
491_T	542_Q	0.662	0.44
43_A	162_I	0.661	0.44
21_A	234_F	0.660	0.43
197_R	542_Q	0.660	0.43
82_W	373_G	0.660	0.43
131_G	165_T	0.659	0.43
412_I	503_S	0.657	0.43
158_G	524_T	0.654	0.43
48_A	190_E	0.652	0.43
292_T	399_G	0.649	0.42
137_A	176_P	0.649	0.42
406_A	410_Y	0.649	0.42
26_L	228_V	0.647	0.42
189_F	192_G	0.645	0.42
118_M	122_G	0.644	0.42
506_I	518_S	0.643	0.42
392_S	395_I	0.643	0.42
250_P	254_S	0.643	0.42
308_F	378_F	0.642	0.42
419_A	501_P	0.641	0.42
462_S	465_A	0.640	0.42
88_V	173_M	0.640	0.42
257_V	321_F	0.639	0.41
267_K	296_A	0.639	0.41
460_D	494_V	0.638	0.41
36_K	42_A	0.635	0.41
37_L	42_A	0.635	0.41
58_Y	303_W	0.635	0.41
221_K	263_T	0.634	0.41
115_R	222_E	0.634	0.41
36_K	101_D	0.634	0.41
121_V	125_F	0.634	0.41
52_A	63_A	0.634	0.41
97_T	449_L	0.633	0.41
460_D	464_N	0.633	0.41
131_G	536_G	0.632	0.41
127_A	454_V	0.632	0.41
376_I	501_P	0.631	0.41
459_S	462_S	0.629	0.41
62_V	390_K	0.628	0.40
315_L	325_F	0.628	0.40
139_V	507_A	0.626	0.40
199_L	203_T	0.626	0.40
195_V	244_F	0.625	0.40
498_M	513_L	0.625	0.40
225_P	229_V	0.624	0.40
348_A	444_F	0.624	0.40
254_S	312_T	0.621	0.40
179_V	183_V	0.621	0.40
443_T	540_T	0.620	0.40
85_I	89_F	0.620	0.40
168_V	461_T	0.619	0.40
48_A	51_L	0.619	0.40
152_K	155_Y	0.618	0.39
137_A	427_L	0.618	0.39
48_A	146_L	0.615	0.39
193_Q	196_G	0.615	0.39
304_T	348_A	0.615	0.39
214_M	380_A	0.615	0.39
154_L	377_L	0.615	0.39
87_A	133_A	0.614	0.39
306_F	419_A	0.612	0.39
291_H	399_G	0.612	0.39
231_G	235_A	0.611	0.39
164_N	502_Q	0.610	0.39
301_R	382_L	0.610	0.39
201_F	224_W	0.610	0.39
117_Q	436_A	0.610	0.39
311_A	395_I	0.609	0.39
131_G	313_V	0.607	0.38
26_L	350_M	0.607	0.38
122_G	495_T	0.606	0.38
419_A	462_S	0.606	0.38
455_F	504_I	0.606	0.38
278_G	288_T	0.606	0.38
83_I	256_L	0.606	0.38
76_G	222_E	0.605	0.38
217_W	540_T	0.605	0.38
184_T	486_V	0.604	0.38
428_S	456_L	0.603	0.38
286_D	533_C	0.601	0.38
86_A	377_L	0.600	0.38
104_R	492_G	0.599	0.38
62_V	268_R	0.598	0.38
23_L	53_V	0.598	0.38
204_I	232_G	0.598	0.38
19_L	390_K	0.596	0.37
126_G	166_A	0.596	0.37
248_E	372_T	0.596	0.37
434_A	437_H	0.595	0.37
152_K	277_F	0.594	0.37
49_I	53_V	0.594	0.37
239_Y	538_I	0.593	0.37
16_L	25_I	0.593	0.37
444_F	447_P	0.593	0.37
276_R	308_F	0.592	0.37
510_A	520_L	0.591	0.37
23_L	386_W	0.590	0.37
166_A	494_V	0.590	0.37
29_F	519_D	0.590	0.37
171_G	459_S	0.588	0.37
58_Y	404_E	0.588	0.37
133_A	376_I	0.588	0.37
326_A	367_D	0.588	0.37
242_S	250_P	0.587	0.37
219_G	224_W	0.587	0.37
66_L	295_T	0.584	0.36
110_I	154_L	0.584	0.36
218_R	221_K	0.583	0.36
319_P	322_K	0.583	0.36
112_P	255_S	0.581	0.36
390_K	444_F	0.581	0.36
99_Q	299_V	0.580	0.36
46_T	50_A	0.580	0.36
137_A	371_A	0.580	0.36
396_S	399_G	0.580	0.36
493_G	528_S	0.579	0.36
118_M	214_M	0.578	0.36
135_F	171_G	0.577	0.36
395_I	403_K	0.577	0.36
19_L	26_L	0.577	0.36
172_A	176_P	0.576	0.36
408_P	493_G	0.576	0.36
309_L	418_F	0.576	0.36
428_S	465_A	0.576	0.36
502_Q	506_I	0.576	0.36
117_Q	309_L	0.574	0.35
36_K	95_V	0.574	0.35
460_D	490_T	0.574	0.35
421_I	432_A	0.574	0.35
20_I	177_I	0.573	0.35
478_I	540_T	0.573	0.35
173_M	465_A	0.573	0.35
191_I	482_D	0.573	0.35
297_G	311_A	0.572	0.35
102_I	299_V	0.572	0.35
230_A	233_S	0.570	0.35
26_L	66_L	0.570	0.35
85_I	401_T	0.569	0.35
19_L	395_I	0.568	0.35
299_V	307_L	0.568	0.35
25_I	455_F	0.567	0.35
55_L	66_L	0.565	0.35
292_T	382_L	0.565	0.35
438_T	520_L	0.564	0.35
110_I	311_A	0.564	0.35
209_W	217_W	0.563	0.35
200_P	235_A	0.563	0.35
228_V	267_K	0.562	0.34
349_R	352_P	0.562	0.34
49_I	244_F	0.561	0.34
415_V	502_Q	0.560	0.34
290_A	519_D	0.560	0.34
48_A	348_A	0.559	0.34
173_M	506_I	0.559	0.34
491_T	494_V	0.558	0.34
489_N	502_Q	0.558	0.34
228_V	232_G	0.558	0.34
254_S	491_T	0.557	0.34
89_F	398_F	0.556	0.34
415_V	500_S	0.556	0.34
326_A	446_S	0.555	0.34
293_G	537_V	0.555	0.34
213_I	505_A	0.553	0.34
79_P	524_T	0.553	0.34
447_P	501_P	0.552	0.34
208_F	227_V	0.550	0.33
126_G	210_I	0.549	0.33
70_V	385_V	0.549	0.33
146_L	228_V	0.549	0.33
435_L	438_T	0.549	0.33
40_Y	407_L	0.548	0.33
208_F	267_K	0.548	0.33
103_I	455_F	0.546	0.33
237_A	241_S	0.546	0.33
62_V	66_L	0.546	0.33
26_L	56_L	0.545	0.33
124_C	262_L	0.544	0.33
353_V	362_A	0.544	0.33
208_F	211_M	0.543	0.33
138_P	503_S	0.543	0.33
326_A	370_S	0.542	0.33
92_K	277_F	0.541	0.33
217_W	227_V	0.541	0.33
417_A	466_L	0.540	0.33
294_Y	299_V	0.539	0.32
226_A	235_A	0.539	0.32
127_A	164_N	0.539	0.32
422_S	501_P	0.539	0.32
460_D	498_M	0.539	0.32
192_G	460_D	0.538	0.32
479_G	541_L	0.538	0.32
457_T	466_L	0.538	0.32
123_F	237_A	0.537	0.32
141_I	466_L	0.537	0.32
48_A	297_G	0.537	0.32
431_L	506_I	0.536	0.32
472_A	476_Q	0.536	0.32
69_V	475_A	0.535	0.32
293_G	382_L	0.535	0.32
57_F	70_V	0.534	0.32
306_F	418_F	0.533	0.32
124_C	230_A	0.533	0.32
19_L	289_L	0.532	0.32
390_K	395_I	0.532	0.32
55_L	406_A	0.532	0.32
43_A	415_V	0.532	0.32
240_L	270_Q	0.532	0.32
205_I	530_I	0.531	0.32
29_F	53_V	0.531	0.32
131_G	492_G	0.530	0.32
268_R	272_V	0.530	0.32
50_A	53_V	0.529	0.32
28_F	84_I	0.529	0.32
224_W	228_V	0.529	0.32
232_G	237_A	0.529	0.32
45_W	49_I	0.528	0.32
436_A	470_L	0.528	0.32
88_V	137_A	0.527	0.31
68_S	73_F	0.527	0.31
395_I	441_A	0.527	0.31
119_L	124_C	0.526	0.31
107_I	408_P	0.526	0.31
382_L	542_Q	0.526	0.31
381_L	540_T	0.526	0.31
250_P	469_A	0.525	0.31
462_S	501_P	0.525	0.31
176_P	503_S	0.525	0.31
315_L	445_F	0.524	0.31
36_K	162_I	0.524	0.31
30_F	218_R	0.524	0.31
239_Y	251_D	0.521	0.31
126_G	164_N	0.520	0.31
136_G	161_L	0.520	0.31
363_V	381_L	0.520	0.31
159_L	368_W	0.519	0.31
21_A	39_G	0.519	0.31
163_V	238_Q	0.519	0.31
206_V	507_A	0.519	0.31
154_L	158_G	0.519	0.31
482_D	541_L	0.518	0.31
62_V	300_L	0.517	0.31
63_A	386_W	0.516	0.31
47_V	421_I	0.516	0.31
122_G	195_V	0.516	0.31
224_W	295_T	0.515	0.30
312_T	382_L	0.513	0.30
162_I	510_A	0.512	0.30
426_G	541_L	0.511	0.30
504_I	539_T	0.511	0.30
126_G	167_P	0.510	0.30
429_S	433_L	0.510	0.30
291_H	516_K	0.510	0.30
84_I	101_D	0.509	0.30
62_V	311_A	0.509	0.30
91_Y	95_V	0.509	0.30
136_G	373_G	0.509	0.30
241_S	245_I	0.508	0.30
199_L	208_F	0.508	0.30
117_Q	306_F	0.508	0.30
420_F	424_Y	0.507	0.30
420_F	423_N	0.506	0.30
53_V	56_L	0.506	0.30
453_G	467_F	0.506	0.30
267_K	270_Q	0.504	0.30
290_A	391_P	0.504	0.30
188_S	247_P	0.503	0.29
66_L	476_Q	0.503	0.29
51_L	293_G	0.503	0.29
179_V	301_R	0.503	0.29
454_V	500_S	0.502	0.29
217_W	541_L	0.502	0.29
29_F	423_N	0.502	0.29
83_I	372_T	0.502	0.29
201_F	491_T	0.502	0.29
290_A	390_K	0.500	0.29
288_T	301_R	0.500	0.29
65_A	539_T	0.500	0.29

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4r0cA	3	0.8131	99.8	0.871	Contact Map
4r1iA	2	0.8221	99.8	0.875	Contact Map
4f35D	2	0.7241	99.7	0.886	Contact Map
3qe7A	2	0.4628	24.9	0.979	Contact Map
4x5mA	2	0.1633	12.3	0.982	Contact Map
3qnqA	2	0.5082	10.8	0.982	Contact Map
2m67A	1	0.1198	6.7	0.984	Contact Map
2m20A	2	0.0944	5.8	0.984	Contact Map
5a63B	1	0.1543	5	0.985	Contact Map
2kluA	1	0.118	3.5	0.986	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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