NUPX - ECOLI - GREMLIN Contacts

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NUPX - Nucleoside permease NupX

UniProt:	P33021	Sequences: MDVMRSVLGMVVLLTIAFLLSVNKKKISLRTVGAALVLQVVIGGIMLWLPPGRWVAEKVAFGVHKVMAYSDAGSAFIFGSLVGPKMDTLFDGAGFIFGFRVLPAIIFVTALVSILYYIGVMGILIRILGGIFQKALNISKIESFVAVTTIFLGQNEIPAIVKPFIDRLNRNELFTAICSGMASIAGSTMIGYAALGVPVEYLLAASLMAIPGGILFARLLSPATESSQVSFNNLSFTETPPKSIIEAAATGAMTGLKIAAGVATVVMAFVAIIALINGIIGGVGGWFGFEHASLESILGYLLAPLAWVMGVDWSDANLAGSLIGQKLAINEFVAYLNFSPYLQTAGTLDAKTVAIISFALCGFANFGSIGVVVGAFSAVAPHRAPEIAQLGLRALAAATLSNLMSATIAGFFIGLA	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG12029
Length:	416 (399)
Sequences:	1657 (930)
Seq/√Len:	46.6

ECOLI - NUPX PSUT NUPC
BACSU - YUTK NUPC NUPG

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
69_Y	278_G	5.023	1.00
315_D	349_D	4.531	1.00
313_W	316_A	4.227	1.00
277_N	295_E	3.835	1.00
383_R	386_E	3.827	1.00
295_E	337_N	3.769	1.00
23_N	26_K	3.678	1.00
105_I	262_V	3.637	1.00
337_N	340_P	3.482	1.00
175_T	214_I	3.283	1.00
319_A	356_I	3.246	1.00
22_V	393_R	3.194	1.00
170_R	389_Q	2.987	1.00
284_G	292_A	2.941	1.00
161_V	168_L	2.924	1.00
319_A	352_T	2.897	1.00
10_M	404_M	2.739	1.00
12_V	308_V	2.724	1.00
20_L	396_A	2.724	1.00
256_L	260_A	2.609	1.00
77_I	267_M	2.586	1.00
309_M	403_L	2.581	1.00
123_I	127_I	2.538	1.00
392_L	396_A	2.528	1.00
212_G	401_S	2.491	1.00
165_I	380_A	2.479	1.00
114_I	244_I	2.477	1.00
35_A	215_L	2.443	1.00
18_F	24_K	2.409	1.00
22_V	221_S	2.362	1.00
57_E	61_F	2.340	1.00
166_D	382_H	2.315	1.00
325_Q	337_N	2.296	1.00
252_A	268_A	2.271	1.00
17_A	219_L	2.249	1.00
366_F	392_L	2.199	1.00
117_Y	241_P	2.122	1.00
22_V	170_R	2.087	1.00
338_F	351_K	2.041	0.99
66_V	111_L	2.040	0.99
114_I	248_A	2.016	0.99
253_M	261_G	1.987	0.99
118_I	244_I	1.971	0.99
201_Y	358_F	1.933	0.99
72_A	75_A	1.912	0.99
17_A	216_F	1.911	0.99
303_A	320_G	1.907	0.99
309_M	407_T	1.906	0.99
148_T	160_I	1.880	0.99
248_A	272_I	1.867	0.99
7_V	11_V	1.862	0.99
71_D	100_R	1.840	0.99
51_P	55_V	1.815	0.99
209_A	405_S	1.801	0.99
258_I	261_G	1.791	0.99
220_L	397_A	1.770	0.98
170_R	386_E	1.758	0.98
358_F	405_S	1.750	0.98
364_A	402_N	1.749	0.98
142_E	218_R	1.739	0.98
138_I	143_S	1.726	0.98
257_K	260_A	1.722	0.98
327_L	399_T	1.716	0.98
220_L	396_A	1.716	0.98
44_G	412_F	1.706	0.98
131_I	135_A	1.696	0.98
296_S	300_Y	1.681	0.98
169_N	223_A	1.664	0.98
32_V	215_L	1.663	0.98
171_N	223_A	1.659	0.98
45_I	49_L	1.622	0.97
127_I	130_G	1.606	0.97
155_N	258_I	1.604	0.97
5_R	307_W	1.595	0.97
294_L	298_L	1.563	0.97
113_S	117_Y	1.559	0.97
283_V	287_F	1.552	0.97
209_A	212_G	1.544	0.96
20_L	220_L	1.543	0.96
154_Q	372_V	1.534	0.96
8_L	307_W	1.520	0.96
108_V	152_L	1.519	0.96
154_Q	368_S	1.508	0.96
173_L	386_E	1.508	0.96
292_A	297_I	1.507	0.96
33_G	37_V	1.506	0.96
129_G	140_K	1.497	0.96
102_L	263_A	1.497	0.96
307_W	313_W	1.486	0.96
119_G	122_G	1.486	0.96
17_A	400_L	1.485	0.96
93_A	96_I	1.448	0.95
364_A	399_T	1.442	0.95
123_I	126_R	1.434	0.95
271_A	367_G	1.415	0.94
4_M	8_L	1.415	0.94
18_F	27_I	1.405	0.94
23_N	224_T	1.396	0.94
70_S	74_S	1.390	0.94
244_I	248_A	1.385	0.93
64_H	68_A	1.384	0.93
181_M	372_V	1.373	0.93
174_F	397_A	1.370	0.93
261_G	265_V	1.368	0.93
259_A	263_A	1.366	0.93
328_A	366_F	1.357	0.93
55_V	58_K	1.353	0.93
154_Q	367_G	1.351	0.93
275_L	279_I	1.350	0.93
157_I	179_S	1.349	0.93
303_A	313_W	1.344	0.92
193_A	199_V	1.342	0.92
155_N	261_G	1.320	0.92
70_S	271_A	1.315	0.92
354_A	413_I	1.312	0.91
72_A	274_A	1.311	0.91
110_A	248_A	1.301	0.91
256_L	264_T	1.295	0.91
392_L	395_L	1.291	0.91
27_I	219_L	1.281	0.90
169_N	225_E	1.268	0.90
127_I	131_I	1.266	0.90
28_S	31_T	1.263	0.90
65_K	68_A	1.259	0.90
74_S	99_F	1.256	0.90
155_N	375_A	1.252	0.89
15_T	19_L	1.248	0.89
258_I	262_V	1.240	0.89
78_F	98_G	1.240	0.89
300_Y	317_N	1.238	0.89
198_P	342_L	1.225	0.88
246_E	384_A	1.225	0.88
165_I	379_V	1.224	0.88
97_F	367_G	1.224	0.88
65_K	69_Y	1.210	0.88
351_K	355_I	1.205	0.88
169_N	172_E	1.200	0.87
294_L	328_A	1.196	0.87
322_L	341_Y	1.190	0.87
306_A	323_I	1.186	0.87
49_L	52_G	1.186	0.87
175_T	179_S	1.183	0.87
145_V	157_I	1.182	0.86
246_E	250_T	1.179	0.86
81_L	96_I	1.169	0.86
315_D	348_L	1.163	0.86
247_A	251_G	1.160	0.85
314_S	318_L	1.145	0.85
402_N	405_S	1.138	0.84
148_T	152_L	1.135	0.84
279_I	282_G	1.133	0.84
303_A	317_N	1.131	0.84
104_A	187_S	1.120	0.83
110_A	252_A	1.114	0.83
409_A	412_F	1.104	0.82
268_A	370_G	1.104	0.82
38_L	135_A	1.102	0.82
187_S	258_I	1.099	0.82
80_S	96_I	1.094	0.82
158_P	180_G	1.093	0.82
191_G	332_F	1.093	0.82
395_L	399_T	1.079	0.81
292_A	296_S	1.075	0.81
295_E	325_Q	1.073	0.81
45_I	51_P	1.070	0.80
338_F	356_I	1.069	0.80
80_S	93_A	1.068	0.80
284_G	293_S	1.057	0.80
128_L	150_I	1.055	0.79
154_Q	371_V	1.055	0.79
276_I	294_L	1.053	0.79
273_I	329_I	1.053	0.79
14_L	32_V	1.050	0.79
19_L	24_K	1.048	0.79
329_I	333_V	1.042	0.79
61_F	64_H	1.042	0.79
125_I	164_F	1.037	0.78
43_G	352_T	1.037	0.78
342_L	353_V	1.033	0.78
401_S	405_S	1.032	0.78
395_L	398_A	1.031	0.78
42_I	212_G	1.029	0.78
209_A	358_F	1.028	0.78
154_Q	327_L	1.025	0.77
335_Y	361_C	1.025	0.77
366_F	395_L	1.022	0.77
16_I	305_L	1.021	0.77
369_I	372_V	1.019	0.77
16_I	379_V	1.019	0.77
40_V	408_I	1.008	0.76
311_V	319_A	1.006	0.76
145_V	179_S	1.005	0.76
261_G	375_A	0.999	0.76
216_F	397_A	0.994	0.75
313_W	320_G	0.994	0.75
175_T	217_A	0.991	0.75
80_S	84_P	0.990	0.75
341_Y	347_T	0.989	0.75
21_S	219_L	0.986	0.75
330_N	367_G	0.981	0.74
118_I	121_M	0.980	0.74
384_A	398_A	0.972	0.74
376_F	387_I	0.971	0.74
44_G	48_W	0.971	0.74
293_S	296_S	0.968	0.73
62_G	65_K	0.966	0.73
74_S	271_A	0.961	0.73
18_F	219_L	0.960	0.73
160_I	262_V	0.958	0.73
67_M	190_I	0.950	0.72
43_G	320_G	0.949	0.72
59_V	62_G	0.947	0.72
149_T	183_S	0.940	0.71
106_I	255_G	0.937	0.71
5_R	8_L	0.936	0.71
35_A	136_L	0.929	0.70
321_S	325_Q	0.927	0.70
188_T	367_G	0.925	0.70
55_V	59_V	0.925	0.70
40_V	412_F	0.923	0.70
179_S	210_I	0.923	0.70
283_V	286_W	0.921	0.69
14_L	219_L	0.919	0.69
152_L	160_I	0.914	0.69
6_S	351_K	0.913	0.69
132_F	136_L	0.912	0.69
114_I	272_I	0.906	0.68
369_I	391_G	0.903	0.68
83_G	96_I	0.901	0.68
30_R	34_A	0.900	0.68
13_L	216_F	0.899	0.68
138_I	214_I	0.897	0.67
189_M	202_L	0.897	0.67
314_S	349_D	0.890	0.67
284_G	291_H	0.890	0.67
170_R	390_L	0.890	0.67
120_V	350_A	0.889	0.67
13_L	404_M	0.889	0.67
42_I	112_V	0.889	0.67
195_L	336_L	0.887	0.67
195_L	369_I	0.885	0.66
167_R	228_Q	0.884	0.66
326_K	332_F	0.883	0.66
318_L	341_Y	0.880	0.66
369_I	395_L	0.880	0.66
169_N	224_T	0.879	0.66
165_I	176_A	0.877	0.66
280_I	292_A	0.876	0.66
266_V	270_V	0.873	0.65
28_S	137_N	0.867	0.65
125_I	184_I	0.867	0.65
348_L	353_V	0.862	0.64
369_I	387_I	0.862	0.64
295_E	340_P	0.862	0.64
170_R	221_S	0.862	0.64
28_S	33_G	0.861	0.64
206_S	209_A	0.859	0.64
215_L	402_N	0.858	0.64
219_L	308_V	0.855	0.64
16_I	396_A	0.855	0.64
70_S	104_A	0.853	0.64
14_L	411_F	0.852	0.63
146_A	214_I	0.846	0.63
54_W	57_E	0.844	0.63
181_M	398_A	0.844	0.63
309_M	355_I	0.836	0.62
10_M	405_S	0.834	0.62
249_A	253_M	0.833	0.62
120_V	301_L	0.827	0.61
49_L	53_R	0.826	0.61
101_V	259_A	0.824	0.61
76_F	97_F	0.823	0.61
265_V	366_F	0.821	0.61
116_Y	163_P	0.818	0.60
6_S	203_L	0.818	0.60
68_A	71_D	0.818	0.60
37_V	308_V	0.817	0.60
149_T	189_M	0.815	0.60
35_A	48_W	0.811	0.60
41_V	44_G	0.810	0.59
155_N	188_T	0.810	0.59
136_L	176_A	0.809	0.59
112_V	152_L	0.808	0.59
75_A	80_S	0.806	0.59
121_M	163_P	0.805	0.59
189_M	193_A	0.804	0.59
259_A	320_G	0.799	0.58
8_L	162_K	0.798	0.58
34_A	136_L	0.796	0.58
273_I	321_S	0.793	0.58
209_A	402_N	0.791	0.58
59_V	203_L	0.789	0.57
80_S	83_G	0.788	0.57
39_Q	212_G	0.788	0.57
27_I	59_V	0.787	0.57
129_G	143_S	0.787	0.57
299_G	321_S	0.781	0.57
99_F	103_P	0.780	0.57
173_L	383_R	0.778	0.56
129_G	132_F	0.775	0.56
350_A	353_V	0.774	0.56
34_A	37_V	0.773	0.56
355_I	393_R	0.773	0.56
327_L	364_A	0.770	0.56
147_V	191_G	0.768	0.55
318_L	348_L	0.768	0.55
98_G	263_A	0.766	0.55
154_Q	259_A	0.760	0.55
254_T	257_K	0.760	0.55
38_L	253_M	0.759	0.55
185_A	188_T	0.759	0.55
112_V	183_S	0.757	0.54
297_I	301_L	0.756	0.54
365_N	368_S	0.755	0.54
168_L	176_A	0.755	0.54
13_L	309_M	0.753	0.54
112_V	121_M	0.753	0.54
350_A	354_A	0.753	0.54
171_N	218_R	0.750	0.54
358_F	409_A	0.746	0.53
12_V	15_T	0.744	0.53
69_Y	275_L	0.744	0.53
167_R	295_E	0.742	0.53
352_T	356_I	0.742	0.53
8_L	12_V	0.737	0.52
274_A	278_G	0.736	0.52
212_G	405_S	0.735	0.52
43_G	341_Y	0.733	0.52
10_M	292_A	0.731	0.52
53_R	57_E	0.730	0.52
189_M	206_S	0.728	0.51
154_Q	249_A	0.727	0.51
121_M	125_I	0.726	0.51
145_V	176_A	0.726	0.51
28_S	136_L	0.723	0.51
141_I	157_I	0.723	0.51
78_F	103_P	0.722	0.51
184_I	188_T	0.721	0.51
355_I	404_M	0.718	0.50
7_V	385_P	0.717	0.50
358_F	402_N	0.716	0.50
242_K	389_Q	0.714	0.50
216_F	370_G	0.713	0.50
10_M	212_G	0.712	0.50
58_K	62_G	0.710	0.50
171_N	210_I	0.710	0.50
108_V	269_F	0.709	0.50
113_S	241_P	0.708	0.50
371_V	374_G	0.707	0.49
203_L	207_L	0.701	0.49
15_T	18_F	0.700	0.49
84_P	220_L	0.699	0.49
184_I	302_L	0.699	0.49
145_V	213_G	0.699	0.49
36_L	408_I	0.698	0.49
265_V	371_V	0.695	0.48
179_S	351_K	0.693	0.48
202_L	218_R	0.691	0.48
141_I	168_L	0.690	0.48
72_A	277_N	0.690	0.48
71_D	75_A	0.688	0.48
149_T	179_S	0.686	0.47
142_E	175_T	0.685	0.47
95_F	100_R	0.684	0.47
305_L	403_L	0.683	0.47
299_G	320_G	0.683	0.47
18_F	22_V	0.681	0.47
282_G	286_W	0.680	0.47
178_C	362_G	0.679	0.47
147_V	150_I	0.672	0.46
60_A	270_V	0.672	0.46
243_S	292_A	0.670	0.46
317_N	320_G	0.670	0.46
221_S	314_S	0.669	0.46
62_G	114_I	0.669	0.46
164_F	398_A	0.668	0.46
26_K	358_F	0.666	0.45
43_G	313_W	0.665	0.45
132_F	395_L	0.663	0.45
267_M	282_G	0.660	0.45
7_V	411_F	0.659	0.45
399_T	402_N	0.659	0.45
281_G	313_W	0.659	0.45
111_L	272_I	0.658	0.45
177_I	186_G	0.658	0.45
322_L	334_A	0.658	0.45
277_N	293_S	0.657	0.44
165_I	340_P	0.656	0.44
330_N	334_A	0.654	0.44
178_C	301_L	0.654	0.44
112_V	323_I	0.654	0.44
352_T	357_S	0.653	0.44
34_A	162_K	0.652	0.44
45_I	296_S	0.650	0.44
168_L	409_A	0.649	0.44
259_A	262_V	0.649	0.44
141_I	144_F	0.647	0.44
14_L	36_L	0.647	0.44
146_A	330_N	0.646	0.43
35_A	147_V	0.646	0.43
370_G	391_G	0.645	0.43
8_L	308_V	0.644	0.43
385_P	389_Q	0.644	0.43
375_A	387_I	0.644	0.43
330_N	365_N	0.640	0.43
241_P	250_T	0.639	0.43
331_E	334_A	0.637	0.43
364_A	368_S	0.637	0.43
14_L	27_I	0.636	0.42
53_R	200_E	0.636	0.42
40_V	44_G	0.636	0.42
58_K	61_F	0.636	0.42
272_I	342_L	0.635	0.42
14_L	215_L	0.635	0.42
82_V	99_F	0.634	0.42
45_I	55_V	0.634	0.42
165_I	280_I	0.631	0.42
372_V	376_F	0.630	0.42
101_V	332_F	0.630	0.42
82_V	95_F	0.629	0.42
288_G	328_A	0.628	0.42
25_K	134_K	0.628	0.42
350_A	412_F	0.627	0.42
77_I	266_V	0.627	0.42
154_Q	320_G	0.626	0.41
149_T	210_I	0.625	0.41
111_L	264_T	0.624	0.41
170_R	383_R	0.624	0.41
52_G	142_E	0.621	0.41
263_A	266_V	0.620	0.41
370_G	402_N	0.620	0.41
65_K	278_G	0.616	0.41
54_W	106_I	0.613	0.40
119_G	265_V	0.610	0.40
30_R	137_N	0.610	0.40
297_I	320_G	0.607	0.40
109_T	183_S	0.607	0.40
123_I	406_A	0.606	0.40
181_M	394_A	0.605	0.39
148_T	209_A	0.605	0.39
183_S	198_P	0.604	0.39
70_S	100_R	0.604	0.39
54_W	58_K	0.602	0.39
65_K	120_V	0.602	0.39
223_A	227_S	0.602	0.39
311_V	356_I	0.602	0.39
185_A	325_Q	0.601	0.39
355_I	399_T	0.600	0.39
292_A	300_Y	0.599	0.39
187_S	369_I	0.599	0.39
130_G	135_A	0.597	0.39
305_L	389_Q	0.597	0.39
101_V	191_G	0.596	0.39
380_A	386_E	0.592	0.38
138_I	171_N	0.591	0.38
330_N	333_V	0.589	0.38
119_G	123_I	0.589	0.38
102_L	259_A	0.589	0.38
29_L	152_L	0.587	0.38
19_L	260_A	0.586	0.38
149_T	157_I	0.584	0.38
191_G	199_V	0.583	0.37
51_P	54_W	0.582	0.37
403_L	406_A	0.582	0.37
116_Y	122_G	0.581	0.37
19_L	219_L	0.581	0.37
177_I	372_V	0.580	0.37
201_Y	405_S	0.579	0.37
45_I	355_I	0.578	0.37
70_S	216_F	0.577	0.37
107_F	142_E	0.576	0.37
261_G	374_G	0.575	0.37
368_S	371_V	0.574	0.37
139_S	172_E	0.574	0.37
62_G	66_V	0.573	0.36
29_L	33_G	0.572	0.36
121_M	209_A	0.571	0.36
255_G	259_A	0.570	0.36
367_G	371_V	0.570	0.36
281_G	293_S	0.569	0.36
226_S	230_S	0.568	0.36
305_L	308_V	0.568	0.36
191_G	196_G	0.565	0.36
253_M	260_A	0.565	0.36
159_A	258_I	0.564	0.36
64_H	366_F	0.563	0.36
81_L	99_F	0.563	0.36
162_K	311_V	0.563	0.36
129_G	229_V	0.560	0.35
325_Q	330_N	0.560	0.35
201_Y	212_G	0.559	0.35
104_A	210_I	0.558	0.35
84_P	340_P	0.558	0.35
42_I	45_I	0.558	0.35
407_T	410_G	0.557	0.35
221_S	390_L	0.557	0.35
43_G	398_A	0.556	0.35
143_S	153_G	0.555	0.35
144_F	149_T	0.555	0.35
32_V	165_I	0.552	0.35
108_V	159_A	0.551	0.34
52_G	197_V	0.551	0.34
129_G	168_L	0.551	0.34
136_L	179_S	0.550	0.34
43_G	354_A	0.549	0.34
107_F	320_G	0.549	0.34
69_Y	274_A	0.548	0.34
203_L	355_I	0.548	0.34
318_L	347_T	0.547	0.34
149_T	180_G	0.546	0.34
247_A	324_G	0.546	0.34
146_A	209_A	0.546	0.34
131_I	314_S	0.545	0.34
4_M	248_A	0.545	0.34
188_T	332_F	0.543	0.34
114_I	118_I	0.543	0.34
109_T	159_A	0.542	0.34
399_T	403_L	0.540	0.34
315_D	352_T	0.539	0.33
147_V	179_S	0.538	0.33
56_A	129_G	0.538	0.33
81_L	94_G	0.538	0.33
227_S	267_M	0.537	0.33
387_I	395_L	0.537	0.33
326_K	365_N	0.536	0.33
49_L	220_L	0.536	0.33
149_T	158_P	0.536	0.33
74_S	204_A	0.536	0.33
188_T	371_V	0.536	0.33
6_S	282_G	0.534	0.33
43_G	402_N	0.533	0.33
77_I	108_V	0.533	0.33
215_L	391_G	0.533	0.33
317_N	321_S	0.532	0.33
312_D	318_L	0.531	0.33
38_L	136_L	0.531	0.33
311_V	352_T	0.531	0.33
197_V	360_L	0.531	0.33
262_V	271_A	0.531	0.33
120_V	123_I	0.530	0.33
276_I	374_G	0.530	0.33
105_I	332_F	0.530	0.33
165_I	279_I	0.529	0.33
74_S	407_T	0.529	0.33
258_I	375_A	0.528	0.32
172_E	294_L	0.526	0.32
279_I	318_L	0.525	0.32
157_I	375_A	0.524	0.32
265_V	399_T	0.524	0.32
77_I	263_A	0.523	0.32
298_L	328_A	0.522	0.32
14_L	379_V	0.522	0.32
5_R	9_G	0.522	0.32
216_F	373_V	0.521	0.32
114_I	264_T	0.520	0.32
174_F	178_C	0.520	0.32
256_L	263_A	0.519	0.32
113_S	246_E	0.519	0.32
150_I	210_I	0.518	0.32
74_S	203_L	0.518	0.32
280_I	296_S	0.518	0.32
408_I	411_F	0.518	0.32
262_V	388_A	0.518	0.32
154_Q	271_A	0.517	0.32
9_G	409_A	0.516	0.31
253_M	375_A	0.515	0.31
163_P	381_P	0.515	0.31
152_L	157_I	0.515	0.31
184_I	314_S	0.513	0.31
371_V	375_A	0.513	0.31
6_S	411_F	0.512	0.31
341_Y	346_G	0.512	0.31
183_S	193_A	0.512	0.31
31_T	207_L	0.512	0.31
144_F	160_I	0.512	0.31
17_A	399_T	0.512	0.31
108_V	327_L	0.511	0.31
250_T	384_A	0.511	0.31
138_I	218_R	0.509	0.31
23_N	321_S	0.509	0.31
190_I	194_A	0.508	0.31
139_S	335_Y	0.507	0.31
41_V	137_N	0.506	0.31
201_Y	354_A	0.506	0.31
227_S	231_F	0.506	0.31
147_V	313_W	0.505	0.31
54_W	301_L	0.504	0.30
336_L	339_S	0.504	0.30
289_F	300_Y	0.504	0.30
188_T	265_V	0.503	0.30
97_F	154_Q	0.502	0.30
274_A	277_N	0.502	0.30
171_N	224_T	0.501	0.30
4_M	130_G	0.501	0.30
41_V	45_I	0.501	0.30
248_A	409_A	0.500	0.30
82_V	100_R	0.500	0.30
34_A	135_A	0.500	0.30

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4pd6A	3	0.9591	100	0.111	Contact Map
2cfqA	1	0.8606	54.5	0.975	Contact Map
2mofA	1	0.0769	32.8	0.978	Contact Map
4o6yA	2	0.4519	20.2	0.98	Contact Map
4ikvA	1	0.4159	11.9	0.982	Contact Map
4j05A	3	0.3654	7.3	0.984	Contact Map
4oh3A	2	0.4231	6.2	0.984	Contact Map
4fc4A	3	0.3918	5.7	0.984	Contact Map
4f35D	2	0.863	5.5	0.984	Contact Map
4u0qB	1	0	3	0.986	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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