ALSA - ECOLI - GREMLIN Contacts

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ALSA - D-allose import ATP-binding protein AlsA

UniProt:	P32721	Sequences: MATPYISMAGIGKSFGPVHALKSVNLTVYPGEIHALLGENGAGKSTLMKVLSGIHEPTKGTITINNISYNKLDHKLAAQLGIGIIYQELSVIDELTVLENLYIGRHLTKKICGVNIIDWREMRVRAAMMLLRVGLKVDLDEKVANLSISHKQMLEIAKTLMLDAKVIIMDEPTSSLTNKEVDYLFLIMNQLRKEGTAIVYISHKLAEIRRICDRYTVMKDGSSVCSGIVSDVSNDDIVRLMVGRELQNRFNAMKENVSNLAHETVFEVRNVTSRDRKKVRDISFSVCRGEILGFAGLVGSGRTELMNCLFGVDKRAGGEIRLNGKDISPRSPLDAVKKGMAYITESRRDNGFFPNFSIAQNMAISRSLKDGGYKGAMGLFHEVDEQRTAENQRELLALKCHSVNQNITELSGGNQQKVLISKWLCCCPEVIIFDEPTRGIDVGAKAEIYKVMRQLADDGKVILMVSSELPEIITVCDRIAVFCEGRLTQILTNRDDMSEEEIMAWALPQE	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG11959
Length:	510 (476)
Sequences:	9217 (6118)
Seq/√Len:	280.4

ECOLI - ALSA MGLA YPHE XYLG YTFR ARAG LSRA RBSA YEJF MODF
BACSU - YUFO RBSA YKPA YFMM YKOD
HALSA - Q9HR21
SULSO - Y2030 Y1893

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
61_T	68_S	3.513	1.00
22_K	222_S	3.411	1.00
32_E	214_R	3.311	1.00
267_E	285_S	3.255	1.00
123_R	140_D	3.181	1.00
34_H	216_T	3.148	1.00
393_R	403_V	3.136	1.00
323_N	429_E	3.120	1.00
319_E	326_D	3.118	1.00
15_F	55_H	3.034	1.00
65_N	165_K	2.965	1.00
307_N	313_D	2.937	1.00
269_R	319_E	2.925	1.00
270_N	281_D	2.910	1.00
10_G	23_S	2.871	1.00
267_E	321_R	2.871	1.00
35_A	212_C	2.818	1.00
121_E	125_R	2.762	1.00
127_A	131_L	2.660	1.00
225_C	240_L	2.609	1.00
264_T	267_E	2.571	1.00
141_E	145_N	2.563	1.00
7_S	63_T	2.510	1.00
306_M	465_V	2.505	1.00
7_S	27_T	2.486	1.00
189_N	210_R	2.486	1.00
14_S	19_H	2.486	1.00
263_E	288_R	2.445	1.00
9_A	61_T	2.406	1.00
393_R	400_C	2.348	1.00
228_I	231_D	2.294	1.00
8_M	11_I	2.267	1.00
264_T	285_S	2.260	1.00
125_R	128_M	2.230	1.00
212_C	229_V	2.227	1.00
391_N	395_L	2.205	1.00
71_K	80_L	2.183	1.00
305_L	482_F	2.171	1.00
132_R	194_E	2.167	1.00
33_I	188_M	2.163	1.00
353_F	364_I	2.149	1.00
19_H	22_K	2.143	1.00
268_V	271_V	2.115	1.00
454_Q	458_D	2.100	1.00
480_A	490_I	2.100	1.00
12_G	19_H	2.067	1.00
269_R	321_R	2.036	1.00
464_M	475_V	2.031	1.00
182_D	210_R	2.001	1.00
72_L	76_L	1.991	1.00
280_R	486_R	1.985	1.00
239_R	245_E	1.979	1.00
118_D	121_E	1.978	1.00
292_L	480_A	1.938	1.00
233_S	236_D	1.907	1.00
392_Q	421_S	1.906	1.00
48_M	201_I	1.892	1.00
264_T	287_C	1.884	1.00
10_G	25_N	1.869	1.00
429_E	460_K	1.834	1.00
325_K	338_K	1.800	1.00
48_M	84_I	1.786	1.00
9_A	63_T	1.786	1.00
265_V	461_V	1.785	1.00
286_V	461_V	1.777	1.00
268_V	284_F	1.763	1.00
295_A	472_I	1.742	1.00
92_I	103_I	1.720	1.00
12_G	23_S	1.715	1.00
390_E	394_E	1.714	1.00
433_F	452_M	1.707	1.00
91_V	143_V	1.685	1.00
293_G	476_C	1.671	1.00
322_L	327_I	1.665	1.00
291_I	452_M	1.665	1.00
189_N	192_R	1.664	1.00
63_T	68_S	1.663	1.00
85_I	169_M	1.663	1.00
359_A	404_N	1.652	1.00
306_M	432_I	1.649	1.00
363_A	385_E	1.636	1.00
5_Y	197_A	1.635	1.00
358_I	400_C	1.608	1.00
390_E	403_V	1.597	1.00
440_I	448_I	1.596	1.00
227_G	240_L	1.591	1.00
381_H	384_D	1.588	1.00
64_I	166_V	1.586	1.00
14_S	59_K	1.585	1.00
124_V	128_M	1.564	1.00
11_I	50_V	1.563	1.00
492_T	495_D	1.562	1.00
216_T	223_S	1.546	1.00
98_L	123_R	1.541	1.00
272_T	281_D	1.535	1.00
407_I	418_V	1.530	1.00
190_Q	194_E	1.527	1.00
307_N	350_N	1.511	1.00
286_V	463_L	1.511	1.00
8_M	51_L	1.504	1.00
142_K	145_N	1.503	1.00
165_K	196_T	1.502	1.00
128_M	132_R	1.500	1.00
265_V	323_N	1.500	1.00
400_C	405_Q	1.484	1.00
132_R	190_Q	1.483	1.00
121_E	124_V	1.477	1.00
99_E	119_W	1.474	1.00
405_Q	409_E	1.468	1.00
264_T	288_R	1.464	1.00
227_G	232_V	1.457	1.00
94_E	144_A	1.456	1.00
321_R	326_D	1.454	1.00
67_I	80_L	1.450	1.00
73_D	76_L	1.449	1.00
322_L	430_V	1.449	1.00
380_F	385_E	1.447	1.00
209_R	237_I	1.445	1.00
308_C	315_R	1.440	1.00
346_S	349_D	1.440	1.00
480_A	487_L	1.432	1.00
286_V	292_L	1.432	1.00
192_R	213_D	1.431	1.00
362_M	398_L	1.429	1.00
393_R	398_L	1.427	1.00
395_L	454_Q	1.427	1.00
355_N	408_T	1.426	1.00
286_V	430_V	1.424	1.00
54_I	86_Y	1.424	1.00
293_G	472_I	1.416	1.00
352_F	407_I	1.414	1.00
30_P	197_A	1.412	1.00
330_R	334_D	1.388	1.00
185_F	211_I	1.382	1.00
272_T	317_G	1.377	1.00
10_G	59_K	1.376	1.00
384_D	387_R	1.368	1.00
93_D	151_K	1.362	1.00
101_L	126_A	1.354	1.00
232_V	236_D	1.341	1.00
387_R	391_N	1.335	1.00
28_V	166_V	1.331	1.00
261_A	287_C	1.329	1.00
25_N	223_S	1.329	1.00
16_G	19_H	1.328	1.00
76_L	79_Q	1.328	1.00
127_A	139_L	1.326	1.00
183_Y	186_L	1.323	1.00
71_K	76_L	1.322	1.00
250_F	474_T	1.320	1.00
147_S	150_H	1.318	1.00
97_V	137_V	1.315	1.00
14_S	58_T	1.313	1.00
12_G	59_K	1.311	1.00
116_I	379_L	1.296	1.00
236_D	239_R	1.281	1.00
96_T	99_E	1.275	1.00
129_M	161_M	1.273	1.00
270_N	283_S	1.264	1.00
288_R	429_E	1.263	1.00
284_F	294_F	1.261	1.00
227_G	231_D	1.261	1.00
52_S	84_I	1.254	1.00
279_V	308_C	1.251	1.00
138_D	141_E	1.247	1.00
290_E	478_R	1.247	1.00
333_L	337_K	1.243	1.00
356_F	360_Q	1.242	1.00
391_N	394_E	1.241	1.00
269_R	285_S	1.240	1.00
190_Q	193_K	1.232	1.00
284_F	480_A	1.225	1.00
401_H	405_Q	1.220	1.00
454_Q	457_D	1.216	1.00
478_R	490_I	1.204	1.00
288_R	461_V	1.202	1.00
386_Q	404_N	1.199	1.00
215_Y	229_V	1.188	1.00
406_N	409_E	1.180	1.00
223_S	226_S	1.176	1.00
214_R	228_I	1.173	1.00
445_K	468_E	1.170	1.00
427_C	458_D	1.167	1.00
294_F	480_A	1.160	1.00
277_K	280_R	1.158	1.00
451_V	454_Q	1.154	1.00
331_S	334_D	1.140	1.00
188_M	198_I	1.139	1.00
206_A	234_N	1.136	1.00
27_T	214_R	1.136	1.00
370_D	388_T	1.132	1.00
227_G	236_D	1.132	1.00
472_I	476_C	1.131	1.00
419_L	422_K	1.131	1.00
16_G	20_A	1.122	1.00
131_L	136_K	1.121	1.00
34_H	226_S	1.119	1.00
109_K	118_D	1.117	1.00
343_I	433_F	1.108	1.00
358_I	418_V	1.107	1.00
402_S	405_Q	1.105	1.00
279_V	282_I	1.098	1.00
292_L	490_I	1.096	1.00
217_V	240_L	1.094	1.00
30_P	165_K	1.093	1.00
24_V	218_M	1.089	1.00
169_M	198_I	1.086	1.00
303_T	345_E	1.085	1.00
216_T	226_S	1.084	1.00
98_L	139_L	1.080	1.00
133_V	157_A	1.073	1.00
388_T	425_C	1.071	1.00
271_V	308_C	1.071	1.00
101_L	161_M	1.070	1.00
188_M	211_I	1.070	1.00
275_D	316_A	1.066	1.00
37_L	205_L	1.057	1.00
209_R	233_S	1.054	1.00
284_F	292_L	1.053	1.00
397_A	447_E	1.052	1.00
189_N	193_K	1.051	1.00
29_Y	32_E	1.050	1.00
270_N	317_G	1.048	1.00
466_S	472_I	1.048	1.00
209_R	234_N	1.048	1.00
5_Y	166_V	1.045	1.00
281_D	486_R	1.044	1.00
237_I	243_G	1.042	1.00
362_M	389_A	1.042	1.00
472_I	479_I	1.038	1.00
5_Y	65_N	1.034	1.00
344_T	350_N	1.032	1.00
292_L	463_L	1.032	1.00
392_Q	398_L	1.029	1.00
107_L	122_M	1.024	1.00
452_M	464_M	1.023	1.00
123_R	127_A	1.022	1.00
357_S	360_Q	1.021	1.00
359_A	386_Q	1.019	1.00
76_L	80_L	1.013	1.00
57_P	70_N	1.012	1.00
427_C	460_K	1.011	1.00
263_E	323_N	1.011	1.00
164_A	167_I	1.004	1.00
30_P	65_N	1.004	1.00
453_R	457_D	1.002	1.00
21_L	50_V	0.996	1.00
186_L	190_Q	0.994	1.00
28_V	197_A	0.991	1.00
265_V	288_R	0.987	1.00
329_P	334_D	0.983	1.00
120_R	124_V	0.983	1.00
359_A	403_V	0.982	1.00
483_C	488_T	0.981	1.00
435_E	467_S	0.981	1.00
6_I	64_I	0.980	1.00
268_V	309_L	0.979	1.00
353_F	356_F	0.977	1.00
88_E	438_R	0.973	1.00
49_K	55_H	0.973	1.00
97_V	146_L	0.969	1.00
128_M	131_L	0.966	1.00
271_V	315_R	0.965	1.00
12_G	22_K	0.963	1.00
5_Y	64_I	0.963	1.00
253_M	457_D	0.960	1.00
107_L	125_R	0.959	1.00
139_L	142_K	0.958	1.00
302_R	434_D	0.958	1.00
209_R	229_V	0.955	1.00
269_R	283_S	0.953	1.00
294_F	463_L	0.952	1.00
431_I	460_K	0.950	1.00
359_A	385_E	0.950	1.00
432_I	465_V	0.948	1.00
167_I	198_I	0.946	1.00
88_E	348_R	0.944	1.00
29_Y	214_R	0.942	1.00
362_M	418_V	0.939	1.00
262_H	288_R	0.935	1.00
450_K	454_Q	0.935	1.00
329_P	335_A	0.933	1.00
75_K	79_Q	0.933	1.00
268_V	320_I	0.932	1.00
452_M	475_V	0.930	1.00
251_N	474_T	0.929	1.00
275_D	278_K	0.929	1.00
83_G	164_A	0.929	1.00
182_D	186_L	0.922	1.00
9_A	25_N	0.922	1.00
339_G	429_E	0.920	1.00
69_Y	80_L	0.914	1.00
97_V	141_E	0.911	1.00
389_A	403_V	0.910	1.00
401_H	409_E	0.910	1.00
83_G	159_T	0.910	1.00
452_M	462_I	0.905	1.00
56_E	70_N	0.902	1.00
130_L	157_A	0.901	1.00
125_R	163_D	0.900	1.00
310_F	423_W	0.898	1.00
341_A	423_W	0.896	1.00
288_R	323_N	0.895	1.00
23_S	59_K	0.893	1.00
294_F	305_L	0.893	1.00
335_A	340_M	0.891	1.00
455_L	460_K	0.890	1.00
279_V	305_L	0.889	1.00
348_R	354_P	0.889	1.00
363_A	367_S	0.888	1.00
383_V	387_R	0.886	1.00
78_A	162_L	0.885	1.00
340_M	430_V	0.883	1.00
124_V	127_A	0.883	1.00
329_P	340_M	0.877	1.00
6_I	51_L	0.875	1.00
208_I	229_V	0.873	1.00
188_M	200_Y	0.870	1.00
27_T	226_S	0.864	1.00
51_L	62_I	0.863	1.00
303_T	434_D	0.861	1.00
310_F	432_I	0.860	1.00
386_Q	403_V	0.860	1.00
388_T	391_N	0.859	1.00
107_L	117_I	0.858	1.00
336_V	423_W	0.858	1.00
332_P	335_A	0.855	1.00
108_T	118_D	0.854	1.00
344_T	419_L	0.853	1.00
214_R	226_S	0.850	1.00
432_I	463_L	0.848	1.00
354_P	407_I	0.848	1.00
102_Y	125_R	0.846	1.00
98_L	122_M	0.845	1.00
343_I	419_L	0.843	1.00
476_C	493_N	0.843	1.00
23_S	222_S	0.838	1.00
358_I	410_L	0.834	1.00
341_A	431_I	0.830	1.00
50_V	57_P	0.829	1.00
365_S	423_W	0.828	1.00
359_A	389_A	0.827	1.00
237_I	241_M	0.825	1.00
390_E	393_R	0.825	1.00
108_T	115_N	0.823	1.00
102_Y	122_M	0.821	1.00
52_S	86_Y	0.820	0.99
71_K	77_A	0.815	0.99
13_K	58_T	0.814	0.99
105_R	162_L	0.814	0.99
129_M	157_A	0.812	0.99
33_I	189_N	0.812	0.99
34_H	214_R	0.809	0.99
392_Q	425_C	0.808	0.99
446_A	450_K	0.807	0.99
62_I	71_K	0.807	0.99
47_L	218_M	0.805	0.99
126_A	139_L	0.804	0.99
236_D	240_L	0.804	0.99
50_V	55_H	0.803	0.99
341_A	428_P	0.803	0.99
33_I	192_R	0.800	0.99
8_M	26_L	0.798	0.99
135_L	153_M	0.797	0.99
105_R	161_M	0.796	0.99
169_M	188_M	0.795	0.99
127_A	140_D	0.793	0.99
159_T	167_I	0.791	0.99
369_K	427_C	0.790	0.99
284_F	305_L	0.788	0.99
127_A	138_D	0.786	0.99
241_M	244_R	0.780	0.99
215_Y	237_I	0.779	0.99
348_R	415_Q	0.777	0.99
215_Y	227_G	0.776	0.99
282_I	305_L	0.776	0.99
163_D	194_E	0.775	0.99
282_I	487_L	0.774	0.99
64_I	69_Y	0.774	0.99
302_R	345_E	0.774	0.99
291_I	453_R	0.773	0.99
266_F	286_V	0.771	0.99
360_Q	385_E	0.770	0.99
91_V	151_K	0.766	0.99
362_M	421_S	0.764	0.99
285_S	490_I	0.764	0.99
175_S	298_V	0.758	0.99
298_V	467_S	0.758	0.99
49_K	86_Y	0.757	0.99
366_R	369_K	0.757	0.99
89_L	148_I	0.754	0.99
109_K	116_I	0.752	0.99
28_V	199_V	0.750	0.99
29_Y	228_I	0.750	0.99
366_R	425_C	0.748	0.99
123_R	139_L	0.748	0.99
357_S	404_N	0.747	0.99
276_R	316_A	0.747	0.99
14_S	20_A	0.746	0.99
134_G	190_Q	0.744	0.99
265_V	430_V	0.743	0.99
155_E	158_K	0.743	0.99
351_G	419_L	0.742	0.99
400_C	410_L	0.740	0.99
130_L	139_L	0.740	0.99
143_V	154_L	0.737	0.99
238_V	243_G	0.737	0.99
386_Q	390_E	0.737	0.99
361_N	364_I	0.736	0.99
487_L	490_I	0.734	0.99
94_E	142_K	0.731	0.99
473_I	479_I	0.729	0.99
272_T	279_V	0.728	0.99
8_M	62_I	0.728	0.99
294_F	306_M	0.727	0.99
376_A	381_H	0.726	0.99
394_E	397_A	0.723	0.99
264_T	269_R	0.721	0.99
275_D	279_V	0.719	0.99
167_I	196_T	0.718	0.99
99_E	106_H	0.717	0.99
98_L	107_L	0.716	0.99
9_A	27_T	0.716	0.99
322_L	340_M	0.714	0.99
449_Y	474_T	0.714	0.99
266_F	430_V	0.713	0.99
49_K	54_I	0.712	0.99
334_D	337_K	0.707	0.99
354_P	408_T	0.707	0.99
259_N	262_H	0.706	0.98
243_G	246_L	0.706	0.98
83_G	162_L	0.705	0.98
24_V	223_S	0.705	0.98
109_K	115_N	0.704	0.98
228_I	232_V	0.700	0.98
384_D	388_T	0.699	0.98
473_I	493_N	0.699	0.98
16_G	401_H	0.698	0.98
420_I	448_I	0.697	0.98
96_T	142_K	0.696	0.98
242_V	246_L	0.695	0.98
101_L	154_L	0.694	0.98
35_A	229_V	0.692	0.98
262_H	287_C	0.690	0.98
26_L	34_H	0.688	0.98
74_H	77_A	0.687	0.98
132_R	163_D	0.686	0.98
308_C	313_D	0.684	0.98
91_V	154_L	0.684	0.98
329_P	338_K	0.682	0.98
240_L	243_G	0.680	0.98
146_L	154_L	0.680	0.98
206_A	210_R	0.679	0.98
320_I	329_P	0.679	0.98
334_D	338_K	0.678	0.98
371_G	378_G	0.677	0.98
271_V	320_I	0.676	0.98
127_A	136_K	0.675	0.98
6_I	166_V	0.675	0.98
400_C	403_V	0.673	0.98
253_M	477_D	0.673	0.98
327_I	338_K	0.673	0.98
387_R	390_E	0.669	0.98
341_A	426_C	0.668	0.98
428_P	431_I	0.668	0.98
315_R	328_S	0.667	0.98
134_G	186_L	0.665	0.98
267_E	324_G	0.663	0.98
352_F	415_Q	0.661	0.98
263_E	287_C	0.659	0.98
189_N	211_I	0.659	0.98
106_H	122_M	0.654	0.98
184_L	188_M	0.654	0.98
119_W	123_R	0.653	0.98
365_S	426_C	0.653	0.98
453_R	477_D	0.651	0.97
209_R	232_V	0.650	0.97
265_V	286_V	0.650	0.97
16_G	22_K	0.649	0.97
37_L	208_I	0.647	0.97
102_Y	126_A	0.647	0.97
86_Y	90_S	0.647	0.97
48_M	168_I	0.647	0.97
36_L	199_V	0.647	0.97
129_M	132_R	0.646	0.97
252_A	453_R	0.646	0.97
456_A	462_I	0.644	0.97
305_L	309_L	0.643	0.97
430_V	463_L	0.642	0.97
420_I	440_I	0.642	0.97
261_A	264_T	0.641	0.97
428_P	460_K	0.641	0.97
192_R	198_I	0.641	0.97
310_F	342_Y	0.641	0.97
89_L	155_E	0.641	0.97
90_S	155_E	0.639	0.97
358_I	393_R	0.638	0.97
187_I	190_Q	0.636	0.97
125_R	129_M	0.636	0.97
98_L	140_D	0.636	0.97
5_Y	30_P	0.636	0.97
71_K	82_I	0.635	0.97
21_L	218_M	0.630	0.97
177_T	181_V	0.630	0.97
200_Y	204_K	0.629	0.97
306_M	342_Y	0.628	0.97
107_L	121_E	0.627	0.97
29_Y	197_A	0.627	0.97
294_F	482_F	0.626	0.97
146_L	150_H	0.626	0.97
28_V	34_H	0.626	0.97
284_F	463_L	0.625	0.97
8_M	168_I	0.624	0.97
395_L	451_V	0.624	0.97
202_S	208_I	0.624	0.97
130_L	135_L	0.624	0.97
322_L	338_K	0.623	0.97
398_L	421_S	0.623	0.97
268_V	315_R	0.621	0.97
371_G	379_L	0.619	0.97
217_V	237_I	0.619	0.97
89_L	174_S	0.618	0.97
244_R	250_F	0.618	0.97
205_L	208_I	0.618	0.97
366_R	370_D	0.618	0.97
98_L	126_A	0.616	0.96
235_D	245_E	0.613	0.96
405_Q	408_T	0.612	0.96
69_Y	72_L	0.612	0.96
166_V	197_A	0.610	0.96
357_S	406_N	0.609	0.96
7_S	66_N	0.608	0.96
107_L	118_D	0.608	0.96
455_L	458_D	0.606	0.96
108_T	116_I	0.606	0.96
388_T	392_Q	0.604	0.96
26_L	199_V	0.604	0.96
481_V	488_T	0.604	0.96
259_N	457_D	0.604	0.96
101_L	129_M	0.603	0.96
420_I	424_L	0.603	0.96
282_I	482_F	0.602	0.96
399_K	405_Q	0.599	0.96
20_A	401_H	0.599	0.96
306_M	434_D	0.599	0.96
239_R	243_G	0.598	0.96
134_G	183_Y	0.598	0.96
178_N	182_D	0.597	0.96
272_T	280_R	0.597	0.96
229_V	232_V	0.597	0.96
298_V	302_R	0.596	0.96
89_L	175_S	0.596	0.96
218_M	223_S	0.595	0.96
26_L	36_L	0.595	0.96
174_S	438_R	0.595	0.96
129_M	133_V	0.594	0.96
219_K	224_V	0.594	0.96
407_I	422_K	0.594	0.96
428_P	433_F	0.594	0.96
34_H	199_V	0.593	0.96
271_V	279_V	0.593	0.96
248_N	251_N	0.592	0.96
310_F	336_V	0.591	0.96
124_V	131_L	0.589	0.95
123_R	126_A	0.589	0.95
382_E	385_E	0.588	0.95
64_I	80_L	0.587	0.95
264_T	268_V	0.586	0.95
200_Y	211_I	0.586	0.95
238_V	241_M	0.586	0.95
141_E	150_H	0.585	0.95
185_F	192_R	0.585	0.95
148_I	151_K	0.583	0.95
181_V	204_K	0.583	0.95
18_V	401_H	0.583	0.95
392_Q	395_L	0.583	0.95
358_I	407_I	0.582	0.95
8_M	25_N	0.581	0.95
148_I	174_S	0.581	0.95
220_D	399_K	0.579	0.95
343_I	420_I	0.578	0.95
396_L	424_L	0.578	0.95
389_A	393_R	0.578	0.95
358_I	409_E	0.578	0.95
148_I	438_R	0.577	0.95
39_E	244_R	0.576	0.95
186_L	210_R	0.576	0.95
179_K	182_D	0.575	0.95
181_V	211_I	0.575	0.95
93_D	144_A	0.574	0.95
420_I	433_F	0.573	0.95
354_P	422_K	0.572	0.95
464_M	476_C	0.571	0.95
363_A	388_T	0.571	0.95
97_V	139_L	0.571	0.95
366_R	426_C	0.571	0.95
307_N	312_V	0.568	0.94
177_T	180_E	0.568	0.94
310_F	332_P	0.567	0.94
75_K	78_A	0.567	0.94
14_S	22_K	0.567	0.94
144_A	151_K	0.566	0.94
481_V	491_L	0.566	0.94
295_A	469_L	0.566	0.94
234_N	237_I	0.565	0.94
306_M	463_L	0.564	0.94
270_N	319_E	0.564	0.94
97_V	154_L	0.564	0.94
133_V	153_M	0.563	0.94
241_M	245_E	0.561	0.94
407_I	419_L	0.559	0.94
200_Y	208_I	0.558	0.94
363_A	370_D	0.558	0.94
482_F	487_L	0.555	0.94
252_A	477_D	0.554	0.94
186_L	189_N	0.554	0.94
191_L	196_T	0.552	0.94
479_I	493_N	0.552	0.94
254_K	457_D	0.551	0.94
88_E	155_E	0.551	0.94
291_I	475_V	0.551	0.94
33_I	213_D	0.550	0.94
396_L	421_S	0.550	0.94
243_G	247_Q	0.549	0.93
205_L	237_I	0.548	0.93
238_V	242_V	0.548	0.93
160_L	191_L	0.548	0.93
186_L	193_K	0.547	0.93
449_Y	453_R	0.547	0.93
323_N	326_D	0.546	0.93
50_V	58_T	0.545	0.93
141_E	146_L	0.545	0.93
455_L	462_I	0.545	0.93
302_R	467_S	0.544	0.93
292_L	461_V	0.543	0.93
304_E	313_D	0.542	0.93
119_W	122_M	0.542	0.93
8_M	50_V	0.542	0.93
246_L	250_F	0.541	0.93
264_T	321_R	0.541	0.93
272_T	277_K	0.541	0.93
276_R	280_R	0.540	0.93
294_F	487_L	0.540	0.93
225_C	232_V	0.540	0.93
396_L	451_V	0.539	0.93
212_C	215_Y	0.539	0.93
16_G	405_Q	0.539	0.93
308_C	314_K	0.538	0.93
137_V	157_A	0.537	0.93
64_I	82_I	0.535	0.93
293_G	466_S	0.534	0.93
272_T	316_A	0.533	0.92
392_Q	396_L	0.533	0.92
235_D	239_R	0.533	0.92
358_I	405_Q	0.532	0.92
39_E	241_M	0.531	0.92
10_G	61_T	0.530	0.92
149_S	298_V	0.530	0.92
440_I	451_V	0.528	0.92
100_N	143_V	0.528	0.92
26_L	197_A	0.528	0.92
33_I	211_I	0.527	0.92
206_A	468_E	0.526	0.92
192_R	211_I	0.524	0.92
36_L	48_M	0.522	0.92
267_E	319_E	0.522	0.92
173_T	181_V	0.521	0.92
362_M	392_Q	0.521	0.92
277_K	316_A	0.521	0.92
453_R	475_V	0.521	0.92
191_L	198_I	0.521	0.92
449_Y	475_V	0.520	0.92
172_P	180_E	0.519	0.91
320_I	327_I	0.519	0.91
322_L	429_E	0.519	0.91
275_D	313_D	0.519	0.91
342_Y	350_N	0.519	0.91
310_F	341_A	0.518	0.91
362_M	393_R	0.516	0.91
344_T	351_G	0.516	0.91
355_N	406_N	0.516	0.91
252_A	259_N	0.515	0.91
45_S	49_K	0.515	0.91
351_G	422_K	0.515	0.91
148_I	349_D	0.515	0.91
400_C	409_E	0.515	0.91
136_K	150_H	0.515	0.91
174_S	204_K	0.515	0.91
102_Y	129_M	0.514	0.91
360_Q	363_A	0.514	0.91
449_Y	464_M	0.513	0.91
452_M	456_A	0.512	0.91
453_R	456_A	0.512	0.91
288_R	292_L	0.511	0.91
137_V	141_E	0.510	0.91
14_S	17_P	0.510	0.91
177_T	298_V	0.509	0.91
105_R	125_R	0.509	0.91
329_P	332_P	0.509	0.91
276_R	308_C	0.508	0.91
86_Y	89_L	0.508	0.91
13_K	55_H	0.508	0.91
310_F	335_A	0.507	0.90
12_G	20_A	0.507	0.90
34_H	197_A	0.506	0.90
32_E	197_A	0.506	0.90
73_D	77_A	0.505	0.90
295_A	466_S	0.505	0.90
447_E	450_K	0.504	0.90
17_P	20_A	0.504	0.90
39_E	443_G	0.504	0.90
456_A	461_V	0.503	0.90
107_L	115_N	0.501	0.90
336_V	365_S	0.500	0.90

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4q9hA	1	0.951	100	0.389	Contact Map
4finA	2	0.9098	100	0.397	Contact Map
4f4cA	1	0.9333	100	0.418	Contact Map
1yqtA	1	0.8922	100	0.434	Contact Map
3ux8A	2	0.8529	100	0.438	Contact Map
3bk7A	1	0.9078	100	0.447	Contact Map
3ozxA	1	0.8765	100	0.448	Contact Map
2iw3A	2	0.8961	100	0.451	Contact Map
3j16B	1	0.9078	100	0.461	Contact Map
2vf7A	2	0.9431	100	0.528	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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