GREMLIN Database
YJCS - Putative alkyl/aryl-sulfatase YjcS
UniProt: P32717 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG11955
Length: 661 (621)
Sequences: 801 (567)
Seq/√Len: 22.8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
456_A470_A4.5741.00
434_Y519_F4.4801.00
102_V246_V4.4071.00
281_E302_A4.1441.00
120_K123_D3.9851.00
304_K349_E3.9421.00
305_A352_F3.9401.00
460_S490_N3.8651.00
316_L419_V3.8331.00
282_F300_I3.5541.00
456_A482_L3.5021.00
274_K281_E3.4121.00
128_V160_A3.4111.00
61_D364_H3.3931.00
125_M305_A3.3421.00
176_V189_V3.0751.00
460_S486_V3.0691.00
283_D344_W3.0491.00
297_H311_N3.0181.00
505_E528_R2.9500.99
154_P260_S2.9350.99
164_Y168_R2.8970.99
195_E199_K2.8910.99
78_D82_K2.8680.99
287_T297_H2.8660.99
453_Y485_Q2.8450.99
57_Q61_D2.8310.99
452_R475_D2.8260.99
449_M481_E2.8160.99
158_K162_D2.8100.99
457_L463_V2.7050.99
500_Q504_F2.6800.99
562_D649_D2.6770.99
435_D440_N2.6750.99
370_G588_N2.6660.99
190_K543_D2.6380.99
464_I486_V2.6130.99
287_T311_N2.5800.99
247_G252_V2.5460.98
124_K142_E2.5300.98
266_K275_M2.5110.98
525_K529_E2.4950.98
139_V148_I2.4670.98
462_R466_L2.4410.98
386_L391_Y2.4230.98
110_S247_G2.3880.98
470_A479_S2.3660.98
464_I493_D2.3500.97
338_N595_R2.3460.97
282_F298_F2.3420.97
69_P116_S2.3330.97
36_A101_T2.2990.97
124_K303_L2.2980.97
206_I277_I2.2800.97
470_A482_L2.2430.97
420_S442_H2.2260.96
193_I205_V2.2220.96
307_C352_F2.2180.96
165_F170_Q2.2180.96
456_A466_L2.2100.96
140_E171_K2.1860.96
283_D347_D2.1750.96
554_F575_F2.1710.96
63_Q119_F2.1610.96
312_A337_L2.1580.96
554_F577_M2.1580.96
175_A204_Q2.1370.95
153_T255_A2.1270.95
173_I192_I2.1220.95
186_Y544_T2.0950.95
148_I300_I2.0840.95
183_T259_P2.0820.95
371_K409_N2.0790.95
125_M352_F2.0690.94
479_S503_N2.0590.94
197_D202_K2.0460.94
391_Y399_M2.0240.94
198_V201_G2.0120.94
578_S609_S2.0060.94
250_L356_T2.0050.93
470_A478_W1.9950.93
63_Q115_I1.9850.93
479_S482_L1.9740.93
134_S152_V1.9410.92
418_S513_S1.9280.92
134_S255_A1.9200.92
221_L559_V1.9100.92
384_L387_A1.9050.92
568_G590_S1.9030.92
456_A479_S1.8990.91
274_K283_D1.8850.91
387_A431_L1.8800.91
89_D240_H1.8800.91
120_K124_K1.8470.90
140_E145_I1.8470.90
305_A350_V1.8460.90
145_I164_Y1.8380.90
444_Y475_D1.8360.90
47_Y103_N1.8260.90
140_E168_R1.8140.89
483_L504_F1.8000.89
569_K643_E1.7970.89
155_P258_D1.7950.89
69_P131_Q1.7810.89
283_D343_M1.7810.89
561_L647_C1.7790.88
140_E164_Y1.7630.88
462_R465_N1.7580.88
115_I119_F1.7490.88
468_Q495_V1.7460.88
145_I168_R1.7430.87
424_R433_Y1.7230.87
66_F69_P1.7210.87
181_S292_A1.7010.86
152_V254_L1.6990.86
189_V262_I1.6990.86
204_Q266_K1.6960.86
326_K429_F1.6790.85
440_N484_K1.6530.84
322_L519_F1.6500.84
233_S515_T1.6370.84
178_Y189_V1.6360.84
148_I298_F1.6250.83
468_Q472_K1.6160.83
133_I248_N1.6090.83
487_I500_Q1.6030.83
386_L400_I1.5900.82
319_F330_T1.5840.82
271_T339_E1.5820.82
90_Y245_N1.5750.81
165_F169_P1.5740.81
75_I86_R1.5730.81
138_F145_I1.5640.81
316_L379_I1.5600.81
148_I179_T1.5540.80
466_L470_A1.5510.80
70_L116_S1.5360.80
576_N607_Y1.5280.79
383_T423_A1.5190.79
612_D626_L1.5120.79
320_Y428_N1.5110.79
178_Y262_I1.5000.78
145_I169_P1.4930.78
233_S519_F1.4920.78
190_K260_S1.4870.77
479_S483_L1.4830.77
506_Q509_Y1.4820.77
567_A590_S1.4800.77
51_L413_R1.4660.76
464_I483_L1.4640.76
483_L500_Q1.4640.76
179_T307_C1.4610.76
457_L482_L1.4550.76
341_L366_N1.4430.75
575_F585_L1.4400.75
566_A647_C1.4260.74
56_R60_D1.4240.74
280_L303_L1.4190.74
285_L297_H1.4160.74
583_L594_Y1.4130.74
274_K302_A1.4130.74
604_A634_I1.4000.73
379_I426_V1.4000.73
421_H516_W1.3970.73
280_L300_I1.3900.72
70_L131_Q1.3860.72
122_T303_L1.3840.72
190_K262_I1.3830.72
471_N479_S1.3820.72
563_S647_C1.3820.72
428_N433_Y1.3660.71
298_F307_C1.3650.71
99_P107_W1.3540.70
57_Q364_H1.3520.70
269_V273_E1.3480.70
349_E362_N1.3400.70
494_Q498_N1.3370.69
330_T380_H1.3370.69
313_T353_M1.3350.69
198_V262_I1.3330.69
221_L384_L1.3320.69
212_M263_A1.3300.69
371_K411_A1.3280.69
476_Y506_Q1.3190.68
576_N605_S1.3190.68
190_K195_E1.3150.68
270_R273_E1.3140.68
574_N602_A1.3140.68
379_I419_V1.3140.68
178_Y261_I1.3120.68
162_D166_Q1.3080.68
161_L165_F1.3030.67
152_V255_A1.2820.66
174_V204_Q1.2790.66
308_T340_T1.2780.66
610_R614_H1.2700.65
70_L73_E1.2700.65
345_G349_E1.2660.65
588_N591_V1.2650.65
136_I160_A1.2550.64
440_N443_P1.2500.64
193_I198_V1.2500.64
96_A111_Q1.2340.63
587_L592_L1.2340.63
165_F168_R1.2340.63
299_Y348_A1.2300.63
37_T471_N1.2220.62
40_T510_Q1.2220.62
348_A362_N1.2130.62
549_S552_M1.2090.61
449_M485_Q1.2040.61
209_A269_V1.2040.61
198_V202_K1.2030.61
74_G88_D1.2030.61
110_S252_V1.1940.60
76_L131_Q1.1930.60
212_M261_I1.1870.60
338_N373_R1.1870.60
141_G280_L1.1870.60
222_A384_L1.1870.60
308_T311_N1.1840.60
404_P567_A1.1840.60
561_L587_L1.1810.60
375_T412_S1.1800.59
609_S612_D1.1790.59
214_E326_K1.1750.59
563_S590_S1.1750.59
307_C354_P1.1740.59
143_K278_D1.1720.59
116_S131_Q1.1680.59
138_F147_V1.1650.58
91_K95_N1.1640.58
197_D201_G1.1550.58
48_A53_F1.1500.57
125_M350_V1.1480.57
38_Q41_Q1.1470.57
194_S197_D1.1370.57
105_S415_Y1.1340.56
389_Q649_D1.1330.56
497_K659_T1.1300.56
327_T428_N1.1270.56
146_I277_I1.1260.56
146_I177_I1.1260.56
113_N252_V1.1240.56
74_G131_Q1.1230.56
385_H389_Q1.1170.55
69_P74_G1.1130.55
113_N247_G1.1120.55
206_I275_M1.1120.55
73_E88_D1.1110.55
455_Q466_L1.1090.55
437_N484_K1.1030.54
452_R456_A1.1020.54
88_D91_K1.0970.54
321_T325_A1.0950.54
573_L604_A1.0950.54
623_M632_A1.0900.53
128_V136_I1.0870.53
416_Y515_T1.0850.53
319_F419_V1.0820.53
87_A116_S1.0810.53
233_S321_T1.0810.53
56_R111_Q1.0800.53
86_R89_D1.0770.52
482_L486_V1.0700.52
271_T286_M1.0700.52
449_M453_Y1.0670.52
378_Y564_A1.0650.52
138_F164_Y1.0640.52
418_S516_W1.0560.51
175_A206_I1.0440.50
139_V300_I1.0420.50
295_E310_E1.0350.50
153_T259_P1.0340.49
125_M300_I1.0320.49
393_M431_L1.0290.49
217_S326_K1.0280.49
621_A626_L1.0270.49
297_H308_T1.0270.49
296_M311_N1.0170.48
42_Q46_N1.0140.48
562_D565_K1.0130.48
288_P296_M1.0090.48
316_L422_N1.0080.48
384_L559_V1.0070.48
452_R470_A1.0060.48
574_N584_N1.0050.47
442_H520_Y1.0000.47
206_I282_F0.9990.47
224_N651_F0.9970.47
378_Y563_S0.9960.47
322_L421_H0.9940.47
502_N505_E0.9820.46
38_Q42_Q0.9810.46
507_L520_Y0.9810.46
41_Q100_E0.9790.46
165_F171_K0.9780.46
136_I147_V0.9760.45
500_Q503_N0.9760.45
183_T254_L0.9750.45
197_D200_S0.9740.45
152_V183_T0.9740.45
145_I165_F0.9700.45
141_G172_P0.9690.45
640_K643_E0.9690.45
312_A369_I0.9620.44
45_Q49_K0.9610.44
68_A116_S0.9590.44
290_S336_Y0.9580.44
448_E451_K0.9570.44
41_Q45_Q0.9560.44
457_L479_S0.9550.44
571_I644_I0.9520.44
285_L311_N0.9500.44
179_T298_F0.9480.44
39_Y43_V0.9440.43
181_S294_A0.9430.43
569_K647_C0.9380.43
201_G204_Q0.9370.43
78_D83_V0.9350.43
401_K407_A0.9350.43
232_Y657_I0.9310.42
380_H430_Y0.9260.42
450_G485_Q0.9230.42
288_P311_N0.9220.42
331_S334_T0.9220.42
300_I303_L0.9210.42
119_F230_A0.9210.42
483_L503_N0.9210.42
578_S632_A0.9200.42
177_I300_I0.9190.42
156_A186_Y0.9180.42
272_G339_E0.9180.42
570_N588_N0.9180.42
199_K202_K0.9170.41
466_L482_L0.9150.41
271_T343_M0.9150.41
447_V451_K0.9140.41
134_S150_P0.9130.41
438_P523_G0.9080.41
397_G424_R0.9070.41
141_G146_I0.9010.40
329_D426_V0.8980.40
66_F88_D0.8960.40
490_N493_D0.8940.40
384_L454_V0.8910.40
51_L105_S0.8900.40
66_F116_S0.8890.40
70_L74_G0.8870.39
344_W347_D0.8850.39
74_G87_A0.8830.39
174_V202_K0.8810.39
173_I280_L0.8810.39
287_T308_T0.8810.39
436_G519_F0.8770.39
290_S311_N0.8760.39
225_I657_I0.8750.39
276_I281_E0.8740.39
287_T560_R0.8730.39
195_E262_I0.8700.38
443_P481_E0.8680.38
319_F426_V0.8630.38
466_L479_S0.8610.38
128_V163_L0.8610.38
460_S493_D0.8570.37
287_T290_S0.8570.37
218_E226_M0.8540.37
612_D632_A0.8530.37
551_E581_D0.8510.37
471_N503_N0.8510.37
176_V203_V0.8460.37
142_E648_L0.8450.37
384_L555_D0.8440.37
299_Y347_D0.8420.37
480_A503_N0.8390.36
109_Q356_T0.8380.36
234_Y321_T0.8370.36
445_G448_E0.8360.36
554_F559_V0.8350.36
40_T476_Y0.8340.36
178_Y207_A0.8330.36
563_S567_A0.8310.36
493_D496_A0.8300.36
68_A167_H0.8300.36
146_I280_L0.8290.36
338_N593_N0.8280.36
298_F354_P0.8280.36
468_Q502_N0.8280.36
604_A640_K0.8270.36
176_V192_I0.8260.35
98_A107_W0.8250.35
551_E583_L0.8240.35
178_Y263_A0.8190.35
434_Y523_G0.8180.35
342_D595_R0.8170.35
434_Y441_L0.8160.35
353_M359_V0.8160.35
643_E647_C0.8100.34
78_D84_Y0.8100.34
101_T242_A0.8090.34
155_P257_G0.8070.34
374_D589_D0.8060.34
576_N582_N0.8050.34
76_L220_V0.8040.34
476_Y509_Y0.8030.34
656_N659_T0.8030.34
46_N49_K0.8000.34
206_I268_I0.8000.34
154_P258_D0.8000.34
194_S202_K0.7990.34
102_V107_W0.7960.34
471_N476_Y0.7950.34
550_V581_D0.7930.33
44_N103_N0.7920.33
457_L467_A0.7880.33
53_F56_R0.7880.33
382_Q385_H0.7870.33
573_L585_L0.7860.33
234_Y515_T0.7850.33
226_M325_A0.7840.33
407_A617_L0.7810.33
212_M267_T0.7800.33
550_V575_F0.7790.33
386_L559_V0.7790.33
348_A365_I0.7780.33
290_S296_M0.7780.33
133_I156_A0.7770.32
383_T426_V0.7770.32
128_V220_V0.7760.32
603_D640_K0.7750.32
233_S513_S0.7740.32
487_I504_F0.7740.32
337_L369_I0.7730.32
269_V286_M0.7730.32
239_P525_K0.7730.32
572_S602_A0.7720.32
205_V289_G0.7720.32
456_A463_V0.7720.32
449_M457_L0.7710.32
83_V88_D0.7710.32
41_Q44_N0.7670.32
455_Q473_Q0.7660.32
367_D658_V0.7660.32
141_G278_D0.7660.32
214_E217_S0.7660.32
551_E608_I0.7640.32
164_Y169_P0.7640.32
606_F613_L0.7630.32
310_E421_H0.7610.31
37_T40_T0.7580.31
320_Y379_I0.7550.31
419_V423_A0.7540.31
398_D445_G0.7540.31
61_D64_R0.7530.31
73_E87_A0.7510.31
168_R171_K0.7500.31
176_V194_S0.7500.31
70_L87_A0.7490.31
268_I294_A0.7490.31
367_D588_N0.7480.31
542_P585_L0.7480.31
416_Y427_Y0.7450.31
444_Y452_R0.7440.30
386_L399_M0.7430.30
377_K591_V0.7420.30
470_A500_Q0.7400.30
377_K381_D0.7400.30
179_T287_T0.7380.30
92_F210_G0.7320.30
389_Q562_D0.7300.30
148_I282_F0.7280.30
626_L631_K0.7270.29
585_L592_L0.7270.29
182_H328_R0.7270.29
497_K658_V0.7260.29
369_I554_F0.7250.29
248_N253_T0.7250.29
291_E318_N0.7230.29
375_T402_L0.7230.29
260_S541_S0.7210.29
53_F59_F0.7190.29
66_F173_I0.7190.29
614_H618_T0.7180.29
57_Q60_D0.7170.29
351_L368_Y0.7170.29
529_E647_C0.7160.29
548_M556_F0.7160.29
587_L644_I0.7150.29
320_Y423_A0.7150.29
503_N551_E0.7130.29
314_H359_V0.7130.29
312_A320_Y0.7120.29
47_Y53_F0.7120.29
339_E343_M0.7120.29
37_T44_N0.7120.29
439_A500_Q0.7120.29
178_Y215_A0.7110.29
231_L522_T0.7110.29
290_S429_F0.7110.29
207_A265_T0.7100.29
146_I282_F0.7100.29
56_R646_A0.7090.28
563_S566_A0.7080.28
174_V192_I0.7080.28
467_A499_L0.7060.28
43_V64_R0.7060.28
277_I282_F0.7050.28
571_I640_K0.7050.28
314_H356_T0.7040.28
276_I302_A0.7040.28
288_P336_Y0.7030.28
467_A479_S0.7010.28
233_S356_T0.7000.28
290_S297_H0.6980.28
69_P73_E0.6980.28
212_M549_S0.6970.28
356_T514_A0.6970.28
308_T351_L0.6930.28
639_A642_E0.6930.28
491_P603_D0.6930.28
453_Y481_E0.6930.28
578_S607_Y0.6920.28
73_E116_S0.6910.27
56_R59_F0.6900.27
366_N370_G0.6900.27
367_D371_K0.6890.27
74_G116_S0.6890.27
327_T429_F0.6890.27
61_D359_V0.6880.27
548_M651_F0.6870.27
259_P543_D0.6870.27
397_G445_G0.6870.27
469_E473_Q0.6870.27
56_R77_R0.6860.27
488_A660_P0.6850.27
190_K194_S0.6840.27
323_R328_R0.6840.27
143_K174_V0.6830.27
439_A477_R0.6820.27
282_F307_C0.6820.27
124_K302_A0.6820.27
449_M482_L0.6810.27
484_K504_F0.6800.27
145_I171_K0.6780.27
451_K633_K0.6770.27
522_T525_K0.6770.27
345_G384_L0.6750.27
181_S326_K0.6740.27
550_V610_R0.6740.27
280_L302_A0.6730.26
287_T296_M0.6730.26
656_N660_P0.6700.26
230_A609_S0.6680.26
189_V207_A0.6680.26
47_Y50_S0.6680.26
405_A588_N0.6660.26
183_T431_L0.6660.26
304_K362_N0.6650.26
57_Q367_D0.6650.26
128_V131_Q0.6650.26
373_R414_G0.6640.26
320_Y432_G0.6640.26
141_G361_G0.6640.26
75_I88_D0.6630.26
347_D575_F0.6620.26
225_I655_V0.6620.26
194_S230_A0.6610.26
561_L569_K0.6610.26
215_A219_N0.6610.26
42_Q45_Q0.6600.26
515_T519_F0.6600.26
612_D631_K0.6600.26
72_D166_Q0.6600.26
423_A426_V0.6590.26
471_N499_L0.6580.26
359_V365_I0.6570.26
87_A114_G0.6570.26
119_F227_S0.6540.25
454_V633_K0.6540.25
389_Q651_F0.6540.25
522_T532_H0.6520.25
181_S416_Y0.6520.25
190_K482_L0.6520.25
391_Y520_Y0.6520.25
203_V265_T0.6520.25
133_I356_T0.6500.25
470_A486_V0.6490.25
239_P529_E0.6460.25
145_I354_P0.6450.25
420_S424_R0.6450.25
189_V198_V0.6450.25
133_I183_T0.6450.25
219_N226_M0.6440.25
334_T377_K0.6440.25
350_V360_W0.6430.25
98_A175_A0.6420.25
233_S416_Y0.6420.25
190_K193_I0.6370.25
52_P408_N0.6350.24
36_A41_Q0.6350.24
60_D63_Q0.6340.24
470_A475_D0.6340.24
75_I91_K0.6330.24
58_D108_R0.6330.24
146_I175_A0.6320.24
297_H431_L0.6320.24
125_M194_S0.6310.24
456_A481_E0.6310.24
140_E169_P0.6300.24
405_A589_D0.6290.24
127_Q218_E0.6290.24
161_L171_K0.6280.24
158_K405_A0.6270.24
247_G554_F0.6270.24
46_N50_S0.6270.24
322_L583_L0.6260.24
424_R443_P0.6250.24
234_Y322_L0.6250.24
345_G366_N0.6250.24
117_G127_Q0.6240.24
176_V200_S0.6230.24
634_I641_L0.6210.24
333_W430_Y0.6210.24
54_S294_A0.6200.24
69_P88_D0.6200.24
59_F111_Q0.6200.24
573_L606_F0.6190.24
456_A486_V0.6190.24
493_D568_G0.6190.24
195_E543_D0.6190.24
164_Y354_P0.6180.24
177_I282_F0.6180.24
206_I265_T0.6170.24
480_A504_F0.6170.24
398_D477_R0.6160.24
97_A102_V0.6160.24
418_S421_H0.6150.23
148_I307_C0.6150.23
37_T41_Q0.6150.23
335_E450_G0.6150.23
249_G514_A0.6140.23
67_I167_H0.6130.23
134_S250_L0.6130.23
109_Q314_H0.6130.23
108_R112_I0.6130.23
295_E421_H0.6130.23
134_S153_T0.6120.23
581_D596_K0.6120.23
623_M630_K0.6120.23
486_V493_D0.6120.23
561_L648_L0.6110.23
76_L101_T0.6110.23
304_K347_D0.6110.23
486_V490_N0.6100.23
564_A567_A0.6090.23
67_I294_A0.6090.23
204_Q265_T0.6080.23
105_S413_R0.6080.23
371_K588_N0.6080.23
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204_Q275_M0.6060.23
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152_V168_R0.6040.23
75_I89_D0.6030.23
637_N640_K0.6020.23
98_A287_T0.6020.23
476_Y503_N0.6010.23
99_P337_L0.6010.23
384_L653_L0.6000.23
371_K412_S0.6000.23
90_Y289_G0.5990.23
77_R84_Y0.5990.23
110_S330_T0.5990.23
554_F606_F0.5990.23
469_E472_K0.5980.23
396_I423_A0.5980.23
216_I553_L0.5950.22
109_Q247_G0.5930.22
381_D478_W0.5930.22
486_V499_L0.5920.22
181_S214_E0.5920.22
120_K140_E0.5920.22
125_M139_V0.5910.22
501_A528_R0.5910.22
136_I608_I0.5900.22
247_G354_P0.5900.22
560_R651_F0.5900.22
60_D646_A0.5900.22
471_N506_Q0.5890.22
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318_N323_R0.5880.22
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290_S594_Y0.5880.22
387_A548_M0.5880.22
37_T476_Y0.5870.22
193_I202_K0.5870.22
424_R563_S0.5870.22
302_A344_W0.5860.22
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136_I192_I0.5850.22
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208_P293_P0.5850.22
272_G452_R0.5840.22
335_E551_E0.5840.22
164_Y286_M0.5840.22
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606_F641_L0.5830.22
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162_D634_I0.5820.22
142_E497_K0.5810.22
257_G295_E0.5810.22
246_V591_V0.5810.22
163_L167_H0.5800.22
47_Y365_I0.5800.22
317_H512_E0.5780.22
141_G303_L0.5780.22
221_L387_A0.5780.22
236_L282_F0.5770.22
139_V351_L0.5750.22
77_R83_V0.5750.22
347_D619_G0.5750.22
608_I656_N0.5740.22
235_G520_Y0.5740.22
225_I431_L0.5730.21
66_F70_L0.5720.21
466_L469_E0.5720.21
604_A641_L0.5720.21
245_N518_G0.5710.21
454_V463_V0.5710.21
207_A211_F0.5710.21
117_G129_R0.5700.21
318_N328_R0.5700.21
380_H384_L0.5690.21
320_Y425_A0.5680.21
585_L606_F0.5680.21
83_V479_S0.5670.21
315_T600_P0.5660.21
140_E165_F0.5650.21
174_V277_I0.5650.21
334_T608_I0.5630.21
404_P408_N0.5630.21
291_E325_A0.5630.21
605_S635_I0.5630.21
409_N412_S0.5630.21
175_A277_I0.5630.21
136_I157_A0.5630.21
173_I266_K0.5630.21
402_L406_L0.5620.21
70_L75_I0.5620.21
46_N60_D0.5620.21
465_N469_E0.5620.21
139_V147_V0.5620.21
288_P309_A0.5610.21
372_Y376_I0.5600.21
208_P211_F0.5590.21
331_S377_K0.5580.21
366_N573_L0.5580.21
143_K203_V0.5580.21
341_L373_R0.5570.21
164_Y314_H0.5570.21
139_V469_E0.5570.21
320_Y393_M0.5570.21
283_D595_R0.5570.21
401_K473_Q0.5560.21
543_D618_T0.5560.21
150_P173_I0.5560.21
239_P560_R0.5560.21
567_A587_L0.5560.21
380_H426_V0.5560.21
100_E471_N0.5560.21
482_L503_N0.5550.21
54_S79_A0.5540.21
182_H323_R0.5540.21
36_A40_T0.5540.21
308_T431_L0.5540.21
189_V193_I0.5530.21
131_Q354_P0.5530.21
60_D606_F0.5520.20
42_Q56_R0.5520.20
220_V548_M0.5510.20
331_S344_W0.5510.20
260_S345_G0.5500.20
90_Y139_V0.5490.20
97_A101_T0.5490.20
570_N586_T0.5490.20
578_S585_L0.5480.20
338_N342_D0.5470.20
356_T523_G0.5470.20
452_R478_W0.5470.20
467_A470_A0.5460.20
461_A542_P0.5460.20
606_F638_G0.5460.20
183_T230_A0.5460.20
113_N444_Y0.5460.20
142_E580_G0.5450.20
269_V473_Q0.5450.20
218_E422_N0.5440.20
89_D95_N0.5440.20
634_I638_G0.5440.20
124_K162_D0.5440.20
160_A215_A0.5430.20
269_V607_Y0.5430.20
41_Q80_N0.5420.20
465_N475_D0.5410.20
148_I177_I0.5410.20
80_N83_V0.5410.20
43_V46_N0.5400.20
63_Q66_F0.5400.20
643_E646_A0.5400.20
338_N341_L0.5390.20
332_K343_M0.5390.20
131_Q163_L0.5390.20
414_G477_R0.5380.20
147_V308_T0.5380.20
431_L514_A0.5380.20
67_I362_N0.5380.20
128_V611_E0.5370.20
405_A590_S0.5370.20
315_T319_F0.5370.20
110_S113_N0.5360.20
112_I356_T0.5360.20
128_V138_F0.5360.20
250_L515_T0.5360.20
178_Y296_M0.5360.20
639_A643_E0.5360.20
638_G642_E0.5350.20
230_A445_G0.5350.20
572_S603_D0.5350.20
119_F434_Y0.5350.20
193_I262_I0.5350.20
76_L123_D0.5350.20
283_D299_Y0.5340.20
226_M422_N0.5340.20
318_N417_G0.5340.20
387_A454_V0.5330.20
434_Y462_R0.5330.20
584_N614_H0.5330.20
133_I254_L0.5330.20
257_G310_E0.5320.20
216_I549_S0.5320.20
77_R633_K0.5320.20
66_F115_I0.5320.20
389_Q399_M0.5310.20
330_T434_Y0.5310.20
147_V446_Q0.5310.20
335_E518_G0.5310.20
103_N511_A0.5310.20
577_M586_T0.5300.20
189_V205_V0.5300.20
569_K590_S0.5300.20
276_I461_A0.5300.20
455_Q469_E0.5290.19
48_A267_T0.5290.19
44_N48_A0.5290.19
380_H504_F0.5290.19
258_D590_S0.5280.19
221_L552_M0.5280.19
508_G522_T0.5280.19
341_L345_G0.5270.19
397_G423_A0.5270.19
422_N430_Y0.5270.19
186_Y219_N0.5270.19
572_S587_L0.5270.19
234_Y254_L0.5260.19
66_F340_T0.5260.19
231_L237_L0.5260.19
627_V630_K0.5250.19
385_H563_S0.5250.19
223_G310_E0.5240.19
87_A245_N0.5230.19
125_M137_T0.5230.19
377_K391_Y0.5220.19
54_S95_N0.5220.19
550_V577_M0.5210.19
161_L173_I0.5210.19
168_R286_M0.5210.19
146_I269_V0.5210.19
75_I83_V0.5200.19
385_H398_D0.5200.19
261_I547_G0.5200.19
41_Q56_R0.5190.19
65_G120_K0.5190.19
145_I298_F0.5180.19
164_Y173_I0.5180.19
74_G308_T0.5170.19
478_W634_I0.5170.19
104_P474_G0.5170.19
477_R658_V0.5160.19
53_F410_W0.5160.19
461_A495_V0.5150.19
637_N643_E0.5140.19
272_G286_M0.5130.19
475_D479_S0.5110.19
224_N319_F0.5090.19
220_V290_S0.5090.19
566_A606_F0.5090.19
486_V538_T0.5090.19
626_L630_K0.5080.19
146_I206_I0.5080.19
139_V350_V0.5080.19
442_H510_Q0.5080.19
68_A162_D0.5070.19
219_N325_A0.5060.18
611_E617_L0.5060.18
307_C353_M0.5060.18
192_I316_L0.5060.18
127_Q512_E0.5050.18
364_H656_N0.5050.18
58_D359_V0.5050.18
54_S461_A0.5040.18
38_Q654_W0.5040.18
239_P469_E0.5020.18
42_Q634_I0.5020.18
265_T549_S0.5020.18
117_G293_P0.5020.18
189_V263_A0.5020.18
133_I234_Y0.5010.18
564_A647_C0.5010.18
456_A478_W0.5010.18
62_A85_Y0.5000.18
404_P638_G0.5000.18
54_S246_V0.5000.18
519_F610_R0.5000.18
345_G553_L0.5000.18
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2yheA 3 0.9516 100 0.344 Contact Map
2cfuA 2 0.9425 100 0.357 Contact Map
4pdxA 2 0.9365 100 0.361 Contact Map
4nurA 2 0.9531 100 0.387 Contact Map
2zo4A 1 0.4402 100 0.85 Contact Map
2vw8A 2 0.4463 100 0.856 Contact Map
4ad9A 4 0.4145 100 0.883 Contact Map
2fhxA 2 0.3585 100 0.892 Contact Map
3iogA 1 0.3343 100 0.894 Contact Map
2p18A 1 0.3797 100 0.896 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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