GREMLIN Database
MDTO - Multidrug resistance protein MdtO
UniProt: P32715 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
EcoGene: EG11953
Length: 683 (584)
Sequences: 2430 (1970)
Seq/√Len: 81.5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
202_T281_N4.0371.00
224_N227_C3.9521.00
311_N315_I3.8741.00
220_L224_N3.8621.00
591_W594_T3.7831.00
213_I224_N3.3651.00
364_C383_C3.2571.00
319_L322_L3.2521.00
107_I111_P2.9331.00
582_R586_D2.7611.00
613_F617_L2.6871.00
194_L197_A2.6821.00
110_G362_L2.6751.00
360_A383_C2.6461.00
248_V256_N2.5841.00
577_S581_I2.5291.00
360_A492_V2.5211.00
312_L318_T2.5001.00
110_G358_L2.4611.00
599_Q602_D2.4461.00
84_T88_I2.4371.00
427_V435_P2.4161.00
39_G173_I2.3651.00
436_I439_L2.3631.00
378_T405_A2.3581.00
318_T321_Q2.3351.00
379_C488_I2.3181.00
57_L60_A2.3031.00
105_R109_A2.2771.00
311_N319_L2.2691.00
271_E275_K2.2641.00
428_E431_F2.2551.00
316_C319_L2.2511.00
221_Q225_V2.2461.00
505_E558_R2.2171.00
210_E213_I2.2051.00
144_A148_Y2.2001.00
580_V583_Q2.1881.00
128_V137_I2.1801.00
318_T322_L2.1611.00
252_Y256_N2.1541.00
587_L591_W2.1321.00
430_L434_A2.1271.00
60_A64_Y2.1151.00
213_I217_A2.1101.00
311_N318_T2.1021.00
74_K77_A2.0931.00
217_A228_L2.0911.00
581_I585_R2.0811.00
330_P333_P2.0741.00
104_I108_I2.0461.00
379_C485_G2.0081.00
248_V252_Y1.9971.00
542_R546_H1.9961.00
221_Q224_N1.9951.00
196_D199_S1.9671.00
43_V169_L1.9511.00
205_L208_L1.9321.00
316_C322_L1.9251.00
253_S256_N1.9141.00
210_E224_N1.9071.00
589_H592_D1.8971.00
599_Q603_N1.8961.00
521_S614_A1.8931.00
436_I440_G1.8911.00
172_L176_L1.8751.00
580_V584_G1.8611.00
430_L438_L1.8551.00
108_I112_I1.8341.00
213_I216_E1.7861.00
335_A339_S1.7761.00
431_F435_P1.7761.00
441_A444_A1.7691.00
437_F441_A1.7641.00
360_A496_I1.7571.00
64_Y68_S1.7571.00
252_Y255_L1.7571.00
532_V536_R1.7401.00
382_T486_I1.7291.00
317_Q320_L1.7211.00
314_N325_M1.7151.00
144_A147_D1.7141.00
241_W248_V1.7061.00
302_S305_M1.6941.00
213_I223_L1.6921.00
299_I303_E1.6821.00
299_I302_S1.6821.00
145_M148_Y1.6771.00
489_G493_S1.6751.00
161_V165_Y1.6671.00
255_L259_D1.6571.00
135_V138_Y1.6531.00
367_F492_V1.6401.00
406_F410_I1.6401.00
436_I441_A1.6371.00
210_E214_E1.6261.00
585_R589_H1.6161.00
434_A438_L1.6151.00
405_A460_T1.5981.00
455_T459_V1.5931.00
334_A337_P1.5931.00
195_D288_A1.5931.00
315_I318_T1.5861.00
157_L160_I1.5831.00
619_K634_I1.5771.00
43_V47_S1.5761.00
210_E220_L1.5711.00
581_I584_G1.5561.00
251_I254_T1.5491.00
312_L319_L1.5390.99
378_T482_R1.5250.99
128_V132_V1.5200.99
114_M358_L1.5170.99
117_M357_T1.5150.99
586_D590_A1.5130.99
584_G588_L1.5100.99
268_A271_E1.5060.99
60_A63_F1.5060.99
214_E217_A1.5030.99
132_V137_I1.5010.99
61_V77_A1.4990.99
213_I221_Q1.4940.99
364_C492_V1.4900.99
213_I220_L1.4850.99
429_L441_A1.4760.99
378_T489_G1.4660.99
116_C120_M1.4650.99
221_Q227_C1.4630.99
172_L175_V1.4610.99
224_N228_L1.4600.99
619_K623_G1.4410.99
213_I227_C1.4340.99
311_N321_Q1.4240.99
581_I586_D1.4080.99
334_A339_S1.4080.99
33_T37_W1.4060.99
228_L231_D1.4060.99
538_Y542_R1.3940.99
314_N321_Q1.3890.99
579_T583_Q1.3830.99
450_S453_I1.3810.99
251_I256_N1.3800.99
57_L64_Y1.3740.99
211_T215_R1.3720.99
625_A628_L1.3680.99
437_F440_G1.3630.99
204_S207_P1.3600.99
576_R581_I1.3590.99
463_L467_E1.3580.99
113_L361_C1.3570.99
125_L131_A1.3520.99
614_A618_E1.3480.99
610_A614_A1.3470.99
109_A117_M1.3460.99
217_A220_L1.3440.99
39_G43_V1.3440.99
35_Q46_I1.3380.99
397_K452_Y1.3340.99
341_A344_A1.3340.99
117_M121_R1.3340.99
576_R580_V1.3330.99
428_E432_V1.3300.99
378_T460_T1.3280.98
218_L221_Q1.3270.98
330_P335_A1.3260.98
220_L230_D1.3240.98
407_C457_M1.3150.98
301_E304_A1.3060.98
318_T325_M1.3030.98
436_I443_I1.3000.98
33_T36_L1.2960.98
220_L227_C1.2960.98
243_S246_A1.2870.98
222_K225_V1.2860.98
578_Q581_I1.2810.98
589_H593_A1.2810.98
248_V255_L1.2780.98
318_T323_G1.2780.98
220_L229_A1.2780.98
602_D606_Q1.2740.98
296_D300_S1.2690.98
353_Y389_P1.2660.98
313_E317_Q1.2650.98
217_A224_N1.2620.98
438_L443_I1.2600.98
332_T335_A1.2540.98
81_V171_T1.2500.98
406_F483_A1.2490.98
113_L117_M1.2480.98
586_D589_H1.2480.98
379_C382_T1.2460.98
58_S61_V1.2430.98
131_A136_A1.2430.98
125_L128_V1.2420.98
212_R216_E1.2410.98
334_A338_P1.2400.98
58_S63_F1.2380.98
389_P505_E1.2380.98
114_M351_M1.2320.98
125_L136_A1.2310.98
106_L109_A1.2300.98
352_R501_W1.2290.97
227_C231_D1.2230.97
271_E274_Q1.2200.97
404_G482_R1.2190.97
32_Q35_Q1.2130.97
577_S580_V1.2110.97
257_R262_S1.2080.97
198_I284_Q1.2060.97
270_I273_R1.2030.97
126_G133_A1.1960.97
30_V33_T1.1890.97
58_S85_V1.1870.97
198_I277_A1.1850.97
279_E283_L1.1850.97
437_F442_W1.1840.97
519_M548_A1.1790.97
428_E442_W1.1780.97
256_N260_P1.1760.97
319_L324_Q1.1760.97
204_S208_L1.1760.97
361_C384_V1.1750.97
111_P115_G1.1740.97
214_E225_V1.1730.97
37_W434_A1.1720.97
61_V64_Y1.1710.97
602_D605_L1.1710.97
216_E227_C1.1680.97
312_L315_I1.1680.97
612_Q624_L1.1670.97
631_S635_T1.1650.97
128_V133_A1.1620.96
134_I138_Y1.1560.96
587_L594_T1.1550.96
115_G119_L1.1530.96
592_D595_W1.1520.96
365_Y380_M1.1510.96
518_G625_A1.1490.96
313_E318_T1.1480.96
247_T250_Y1.1430.96
603_N606_Q1.1420.96
129_F133_A1.1400.96
277_A281_N1.1320.96
98_S108_I1.1310.96
277_A280_I1.1310.96
226_F230_D1.1220.96
379_C492_V1.1200.96
40_C43_V1.1150.96
318_T324_Q1.1140.96
72_Y76_V1.1120.95
126_G132_V1.1110.95
359_L530_Q1.1110.95
603_N607_P1.1090.95
97_W101_E1.1070.95
86_L90_S1.0980.95
311_N325_M1.0940.95
64_Y87_E1.0920.95
340_M344_A1.0910.95
295_S299_I1.0890.95
312_L322_L1.0870.95
126_G129_F1.0840.95
271_E276_L1.0830.95
460_T467_E1.0820.95
582_R585_R1.0790.95
109_A113_L1.0750.95
114_M117_M1.0720.94
476_L480_R1.0670.94
249_T252_Y1.0660.94
125_L129_F1.0620.94
585_R592_D1.0580.94
58_S64_Y1.0570.94
577_S584_G1.0570.94
409_A479_I1.0570.94
315_I321_Q1.0540.94
621_A626_T1.0500.94
330_P334_A1.0490.94
434_A437_F1.0470.94
598_A601_L1.0460.94
313_E316_C1.0440.94
584_G592_D1.0440.94
567_S570_R1.0440.94
77_A84_T1.0410.94
210_E216_E1.0370.93
301_E305_M1.0360.93
340_M488_I1.0350.93
321_Q325_M1.0340.93
331_P335_A1.0330.93
391_V563_R1.0290.93
429_L434_A1.0280.93
210_E217_A1.0270.93
312_L325_M1.0260.93
344_A348_P1.0250.93
623_G630_R1.0220.93
313_E323_G1.0210.93
141_T144_A1.0210.93
86_L89_G1.0210.93
40_C44_I1.0200.93
129_F132_V1.0190.93
526_I529_Q1.0190.93
57_L61_V1.0170.93
55_V61_V1.0160.93
75_F79_L1.0150.93
428_E436_I1.0140.93
398_M494_A1.0130.93
316_C324_Q1.0120.93
60_A81_V1.0050.92
217_A221_Q1.0050.92
531_E536_R1.0030.92
322_L325_M1.0030.92
320_L323_G0.9990.92
44_I47_S0.9990.92
429_L437_F0.9980.92
538_Y543_I0.9960.92
222_K231_D0.9840.92
95_Y380_M0.9820.91
482_R489_G0.9810.91
427_V430_L0.9800.91
331_P337_P0.9760.91
405_A486_I0.9750.91
311_N320_L0.9740.91
530_Q534_A0.9720.91
579_T584_G0.9720.91
73_T77_A0.9690.91
504_S563_R0.9670.91
587_L595_W0.9670.91
432_V443_I0.9660.91
432_V441_A0.9640.91
141_T145_M0.9610.91
631_S634_I0.9600.90
191_N284_Q0.9600.90
223_L227_C0.9590.90
405_A482_R0.9570.90
488_I491_V0.9560.90
429_L442_W0.9550.90
56_A67_Q0.9550.90
440_G443_I0.9550.90
109_A116_C0.9540.90
580_V586_D0.9540.90
583_Q591_W0.9530.90
319_L325_M0.9520.90
382_T391_V0.9510.90
299_I305_M0.9490.90
430_L444_A0.9480.90
300_S303_E0.9480.90
527_P531_E0.9470.90
198_I487_I0.9460.90
35_Q179_P0.9460.90
311_N314_N0.9450.90
556_C563_R0.9450.90
215_R220_L0.9440.90
606_Q613_F0.9430.90
98_S104_I0.9420.90
57_L63_F0.9410.90
199_S202_T0.9400.90
272_F282_K0.9400.90
204_S209_P0.9390.89
258_Y262_S0.9390.89
128_V136_A0.9350.89
66_I69_N0.9350.89
213_I219_A0.9340.89
73_T81_V0.9310.89
432_V439_L0.9300.89
590_A595_W0.9280.89
611_G620_Y0.9270.89
606_Q610_A0.9260.89
576_R583_Q0.9250.89
300_S304_A0.9210.89
430_L440_G0.9210.89
343_D348_P0.9200.89
154_R157_L0.9190.88
71_F74_K0.9180.88
435_P438_L0.9180.88
356_K378_T0.9180.88
438_L441_A0.9170.88
584_G593_A0.9170.88
186_M189_A0.9150.88
237_Q241_W0.9130.88
269_I273_R0.9130.88
627_A633_Q0.9130.88
553_E585_R0.9110.88
430_L441_A0.9030.88
250_Y258_Y0.9020.88
585_R588_L0.9020.88
530_Q533_T0.9020.88
130_F137_I0.9010.87
314_N317_Q0.8990.87
457_M460_T0.8990.87
195_D284_Q0.8970.87
282_K326_D0.8970.87
128_V138_Y0.8970.87
254_T260_P0.8970.87
591_W595_W0.8940.87
315_I322_L0.8920.87
55_V58_S0.8910.87
251_I255_L0.8850.87
60_A77_A0.8850.87
223_L226_F0.8850.87
37_W47_S0.8820.86
219_A223_L0.8800.86
198_I281_N0.8790.86
136_A197_A0.8790.86
216_E221_Q0.8790.86
68_S80_F0.8780.86
173_I177_W0.8780.86
275_K281_N0.8760.86
227_C230_D0.8740.86
131_A139_G0.8730.86
220_L223_L0.8720.86
225_V230_D0.8690.86
73_T79_L0.8670.85
619_K628_L0.8660.85
185_Q356_K0.8610.85
238_N242_Q0.8600.85
387_A405_A0.8580.85
68_S74_K0.8580.85
391_V504_S0.8560.85
74_K84_T0.8560.85
106_L362_L0.8550.85
68_S81_V0.8550.85
60_A85_V0.8550.85
436_I461_F0.8530.84
577_S586_D0.8480.84
311_N316_C0.8480.84
252_Y259_D0.8460.84
311_N317_Q0.8460.84
220_L225_V0.8440.84
189_A193_R0.8420.84
134_I137_I0.8420.84
249_T254_T0.8390.83
599_Q607_P0.8390.83
42_L169_L0.8380.83
210_E221_Q0.8380.83
227_C235_R0.8380.83
333_P337_P0.8310.83
601_L605_L0.8290.83
300_S305_M0.8280.83
108_I120_M0.8280.83
622_A626_T0.8270.83
272_F276_L0.8250.82
564_Q567_S0.8240.82
58_S68_S0.8230.82
292_C301_E0.8220.82
65_G85_V0.8220.82
317_Q323_G0.8220.82
64_Y81_V0.8160.82
332_T337_P0.8130.81
317_Q324_Q0.8130.81
103_L107_I0.8130.81
239_A488_I0.8120.81
628_L633_Q0.8120.81
626_T629_S0.8120.81
411_L457_M0.8120.81
589_H596_N0.8100.81
434_A441_A0.8100.81
35_Q40_C0.8100.81
364_C379_C0.8090.81
460_T482_R0.8090.81
46_I50_F0.8090.81
275_K301_E0.8080.81
273_R277_A0.8060.81
340_M499_F0.8050.81
237_Q240_W0.8040.81
54_F58_S0.8040.81
623_G631_S0.8040.81
43_V55_V0.8040.81
205_L209_P0.8030.81
224_N231_D0.8030.81
273_R280_I0.8020.81
37_W41_L0.8020.81
252_Y262_S0.8010.81
63_F463_L0.8010.81
133_A137_I0.7990.80
381_L434_A0.7980.80
623_G628_L0.7980.80
516_T545_L0.7970.80
625_A631_S0.7950.80
617_L622_A0.7940.80
297_W301_E0.7930.80
224_N230_D0.7920.80
66_I88_I0.7910.80
367_F488_I0.7900.80
354_A358_L0.7870.79
618_E629_S0.7840.79
313_E319_L0.7840.79
245_V248_V0.7830.79
586_D593_A0.7820.79
496_I587_L0.7820.79
518_G621_A0.7810.79
581_I592_D0.7800.79
320_L324_Q0.7800.79
137_I141_T0.7790.79
356_K490_T0.7790.79
567_S572_L0.7790.79
249_T253_S0.7780.79
32_Q36_L0.7760.78
354_A368_Y0.7740.78
44_I48_M0.7720.78
333_P336_K0.7720.78
375_G378_T0.7720.78
616_A627_A0.7710.78
197_A406_F0.7710.78
630_R634_I0.7680.78
615_D619_K0.7670.78
412_A489_G0.7670.78
36_L45_L0.7660.77
109_A140_Q0.7650.77
90_S102_P0.7650.77
414_L491_V0.7650.77
314_N324_Q0.7640.77
297_W300_S0.7640.77
612_Q616_A0.7640.77
430_L436_I0.7640.77
130_F133_A0.7630.77
215_R219_A0.7610.77
87_E92_F0.7590.77
331_P336_K0.7580.77
64_Y88_I0.7570.77
257_R261_T0.7570.77
330_P337_P0.7560.77
356_K546_H0.7560.77
630_R633_Q0.7550.76
382_T401_R0.7530.76
220_L231_D0.7520.76
38_V495_V0.7510.76
40_C45_L0.7510.76
312_L323_G0.7500.76
314_N322_L0.7500.76
216_E220_L0.7490.76
105_R376_I0.7480.76
72_Y88_I0.7470.76
315_I319_L0.7460.76
360_A501_W0.7460.76
125_L132_V0.7460.76
71_F77_A0.7460.76
377_H485_G0.7440.75
580_V588_L0.7440.75
213_I231_D0.7430.75
131_A138_Y0.7430.75
597_S605_L0.7410.75
222_K228_L0.7390.75
56_A60_A0.7360.75
587_L592_D0.7350.75
35_Q569_E0.7350.75
545_L594_T0.7350.75
199_S281_N0.7350.75
166_P170_M0.7330.74
279_E282_K0.7320.74
430_L443_I0.7320.74
629_S634_I0.7300.74
315_I323_G0.7300.74
193_R197_A0.7280.74
125_L137_I0.7280.74
382_T542_R0.7270.74
64_Y71_F0.7270.74
525_R614_A0.7260.74
248_V251_I0.7250.74
111_P121_R0.7250.74
297_W303_E0.7250.74
138_Y142_F0.7230.73
254_T257_R0.7230.73
225_V232_A0.7230.73
360_A398_M0.7210.73
451_S454_G0.7200.73
71_F75_F0.7200.73
481_D485_G0.7200.73
429_L440_G0.7180.73
279_E287_V0.7170.73
616_A619_K0.7170.73
628_L631_S0.7160.73
242_Q526_I0.7150.72
616_A623_G0.7120.72
432_V435_P0.7110.72
607_P621_A0.7110.72
537_T541_I0.7110.72
333_P339_S0.7100.72
316_C323_G0.7090.72
368_Y485_G0.7090.72
239_A242_Q0.7080.72
64_Y76_V0.7050.71
390_N393_S0.7020.71
109_A119_L0.7020.71
579_T582_R0.7020.71
248_V253_S0.6990.71
312_L316_C0.6990.71
64_Y67_Q0.6990.71
386_V489_G0.6990.71
521_S525_R0.6990.71
583_Q587_L0.6990.71
475_D481_D0.6980.71
555_M559_V0.6980.71
92_F98_S0.6950.70
148_Y156_T0.6950.70
534_A538_Y0.6930.70
211_T218_L0.6920.70
464_A468_N0.6900.70
380_M467_E0.6890.70
620_Y624_L0.6880.70
284_Q288_A0.6880.70
33_T44_I0.6880.70
43_V46_I0.6870.69
40_C48_M0.6860.69
368_Y380_M0.6840.69
130_F136_A0.6840.69
247_T254_T0.6840.69
335_A338_P0.6810.69
69_N74_K0.6810.69
238_N244_C0.6810.69
106_L118_F0.6810.69
456_Q460_T0.6800.69
629_S635_T0.6790.69
131_A134_I0.6780.68
430_L433_L0.6780.68
228_L232_A0.6770.68
150_E154_R0.6750.68
97_W100_G0.6740.68
66_I486_I0.6730.68
143_P146_L0.6720.68
352_R394_S0.6710.68
35_Q43_V0.6710.68
241_W245_V0.6700.68
547_A551_A0.6690.67
250_Y253_S0.6690.67
60_A68_S0.6690.67
618_E621_A0.6680.67
393_S542_R0.6630.67
195_D285_H0.6630.67
55_V59_L0.6630.67
224_N229_A0.6620.67
608_D616_A0.6610.67
258_Y261_T0.6610.67
83_A88_I0.6600.66
43_V53_P0.6590.66
89_G164_L0.6590.66
166_P542_R0.6590.66
241_W247_T0.6580.66
296_D303_E0.6580.66
585_R590_A0.6580.66
316_C320_L0.6570.66
348_P351_M0.6560.66
388_N397_K0.6560.66
222_K226_F0.6540.66
533_T536_R0.6530.66
231_D235_R0.6530.66
227_C232_A0.6520.65
626_T631_S0.6510.65
68_S71_F0.6500.65
614_A621_A0.6500.65
598_A603_N0.6480.65
421_P506_A0.6480.65
274_Q278_S0.6470.65
69_N353_Y0.6450.65
304_A534_A0.6440.64
470_F473_V0.6420.64
190_L492_V0.6420.64
400_L451_S0.6420.64
58_S80_F0.6410.64
432_V440_G0.6410.64
601_L604_A0.6380.64
72_Y166_P0.6380.64
623_G632_P0.6380.64
602_D607_P0.6370.64
348_P353_Y0.6370.64
58_S84_T0.6330.63
257_R260_P0.6320.63
456_Q459_V0.6310.63
214_E220_L0.6300.63
91_L97_W0.6300.63
197_A449_R0.6300.63
389_P523_V0.6300.63
450_S455_T0.6290.63
608_D614_A0.6290.63
623_G627_A0.6280.63
618_E631_S0.6280.63
210_E228_L0.6280.63
88_I92_F0.6270.62
600_A604_A0.6260.62
110_G121_R0.6260.62
422_W427_V0.6240.62
627_A630_R0.6230.62
553_E557_Q0.6230.62
298_R301_E0.6220.62
199_S212_R0.6220.62
221_Q230_D0.6220.62
625_A632_P0.6210.62
29_R32_Q0.6200.62
378_T486_I0.6190.61
321_Q324_Q0.6180.61
628_L632_P0.6180.61
414_L488_I0.6170.61
219_A227_C0.6160.61
332_T338_P0.6150.61
250_Y410_I0.6130.61
35_Q47_S0.6110.60
310_C318_T0.6110.60
458_V461_F0.6090.60
433_L437_F0.6080.60
330_P338_P0.6080.60
428_E439_L0.6070.60
255_L258_Y0.6070.60
47_S56_A0.6070.60
78_I367_F0.6050.60
107_I509_L0.6040.60
576_R582_R0.6040.60
69_N72_Y0.6030.59
35_Q42_L0.6030.59
249_T258_Y0.6030.59
299_I304_A0.6030.59
486_I504_S0.6020.59
37_W360_A0.6020.59
58_S74_K0.6000.59
278_S282_K0.6000.59
599_Q606_Q0.5990.59
584_G587_L0.5990.59
305_M310_C0.5980.59
293_W299_I0.5970.59
195_D202_T0.5960.59
611_G614_A0.5960.59
514_A621_A0.5950.58
104_I414_L0.5930.58
521_S621_A0.5930.58
130_F139_G0.5920.58
284_Q287_V0.5900.58
272_F289_E0.5900.58
131_A163_G0.5900.58
238_N243_S0.5890.58
353_Y392_G0.5890.58
382_T456_Q0.5890.58
527_P532_V0.5890.58
297_W302_S0.5870.57
42_L48_M0.5870.57
353_Y493_S0.5860.57
313_E320_L0.5850.57
72_Y84_T0.5840.57
76_V80_F0.5840.57
581_I587_L0.5830.57
610_A624_L0.5830.57
467_E478_E0.5820.57
190_L205_L0.5810.57
35_Q39_G0.5800.57
274_Q613_F0.5790.56
63_F79_L0.5790.56
326_D333_P0.5790.56
396_Q400_L0.5790.56
317_Q321_Q0.5780.56
276_L280_I0.5780.56
386_V452_Y0.5770.56
251_I258_Y0.5760.56
229_A232_A0.5760.56
294_Q304_A0.5740.56
277_A300_S0.5730.56
56_A463_L0.5720.55
221_Q228_L0.5700.55
248_V254_T0.5690.55
434_A440_G0.5690.55
412_A465_T0.5680.55
129_F135_V0.5680.55
392_G506_A0.5680.55
74_K178_F0.5680.55
427_V439_L0.5670.55
543_I546_H0.5670.55
628_L635_T0.5650.55
613_F625_A0.5640.54
66_I72_Y0.5640.54
427_V437_F0.5640.54
283_L287_V0.5610.54
106_L110_G0.5610.54
590_A593_A0.5610.54
607_P624_L0.5600.54
610_A622_A0.5590.54
43_V62_L0.5580.54
168_L172_L0.5570.54
254_T258_Y0.5560.53
592_D596_N0.5560.53
36_L43_V0.5550.53
428_E437_F0.5540.53
64_Y74_K0.5540.53
69_N81_V0.5530.53
556_C564_Q0.5520.53
251_I314_N0.5510.53
295_S298_R0.5500.53
217_A225_V0.5500.53
528_R554_E0.5480.52
597_S607_P0.5480.52
84_T87_E0.5480.52
436_I483_A0.5470.52
87_E91_L0.5470.52
409_A483_A0.5470.52
537_T540_Q0.5460.52
35_Q475_D0.5450.52
608_D618_E0.5440.52
127_L133_A0.5410.51
399_V403_G0.5410.51
535_L538_Y0.5410.51
103_L106_L0.5410.51
57_L62_L0.5400.51
214_E224_N0.5400.51
119_L292_C0.5390.51
613_F632_P0.5390.51
504_S559_V0.5390.51
56_A59_L0.5390.51
287_V291_Q0.5380.51
583_Q586_D0.5370.51
376_I485_G0.5370.51
259_D262_S0.5370.51
295_S303_E0.5370.51
275_K278_S0.5360.51
158_W161_V0.5360.51
412_A464_A0.5350.51
367_F611_G0.5350.51
619_K627_A0.5350.51
611_G618_E0.5350.51
191_N195_D0.5350.51
549_F553_E0.5340.51
214_E218_L0.5330.50
311_N323_G0.5330.50
96_K159_C0.5320.50
277_A291_Q0.5320.50
225_V231_D0.5320.50
363_I366_T0.5310.50
463_L520_L0.5300.50
414_L418_L0.5290.50
459_V550_N0.5290.50
330_P336_K0.5270.50
64_Y84_T0.5260.49
346_T500_V0.5260.49
611_G615_D0.5240.49
586_D592_D0.5240.49
143_P149_P0.5210.49
520_L580_V0.5200.49
316_C321_Q0.5200.49
353_Y486_I0.5200.49
416_T485_G0.5190.49
415_F432_V0.5190.49
584_G589_H0.5180.48
29_R360_A0.5160.48
610_A620_Y0.5160.48
235_R278_S0.5150.48
272_F288_A0.5150.48
130_F134_I0.5150.48
556_C579_T0.5150.48
614_A622_A0.5150.48
458_V509_L0.5140.48
296_D301_E0.5140.48
85_V89_G0.5140.48
142_F145_M0.5130.48
615_D629_S0.5130.48
108_I315_I0.5120.48
270_I278_S0.5120.48
36_L39_G0.5120.48
486_I563_R0.5110.48
378_T485_G0.5110.48
541_I545_L0.5110.48
241_W244_C0.5110.48
319_L323_G0.5100.47
590_A594_T0.5090.47
609_R616_A0.5080.47
31_P35_Q0.5080.47
237_Q246_A0.5080.47
114_M118_F0.5080.47
253_S259_D0.5080.47
460_T470_F0.5070.47
85_V88_I0.5070.47
79_L86_L0.5060.47
270_I282_K0.5060.47
316_C325_M0.5060.47
253_S258_Y0.5050.47
610_A623_G0.5050.47
597_S606_Q0.5050.47
538_Y546_H0.5030.46
580_V587_L0.5030.46
358_L362_L0.5020.46
211_T214_E0.5020.46
527_P580_V0.5020.46
219_A226_F0.5020.46
537_T607_P0.5010.46
128_V139_G0.5000.46
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4cgkA 3 0.2372 42.1 0.968 Contact Map
4q4gX 1 0 24.3 0.972 Contact Map
1zzpA 1 0.1567 15.5 0.974 Contact Map
4yayA 1 0.1376 14.3 0.975 Contact Map
1dowA 1 0.2504 13.4 0.975 Contact Map
4jkvA 2 0.142 11 0.976 Contact Map
3wdoA 1 0.3499 10.1 0.976 Contact Map
4m1pA 3 0.1362 8.8 0.977 Contact Map
4pypA 1 0.2504 8.6 0.977 Contact Map
4ltoA 3 0.1962 8.3 0.977 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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