MDTP - ECOLI - GREMLIN Contacts

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MDTP - Multidrug resistance outer membrane protein MdtP

UniProt:	P32714	Sequences: MINRQLSRLLLCSILGSTTLISGCALVRKDSAPHQQLKPEQIKLADDIHLASSGWPQAQWWKQLNDPQLDALIQRTLSGSHTLAEAKLREEKAQSQADLLDAGSQLQVAALGMLNRQRVSANGFLSPYSMDAPALGMDGPYYTEATVGLFAGLDLDLWGVHRSAVAAAIGAHNAALAETAAVELSLATGVAQLYYSMQASYQMLDLLEQTHDVIDYAVKAHQSKVAHGLEAQVPFHGARAQILAVDKQIVAVKGQITETRESLRALIGAGASDMPEIRPVALPQVQTGIPATLSYELLARRPDLQAMRWYVQASLDQVDSARALFYPSFDIKAFFGLDSIHLHTLFKKTSRQFNFIPGLKLPLFDGGRLNANLEGTRAASNMMIERYNQSVLNAVRDVAVNGTRLQTLNDEREMQAERVEATRFTQRAAEAAYQRGLTSRLQATEARLPVLAEEMSLLMLDSRRVIQSIQLMKSLGGGYQAGPVVEKK	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
EcoGene:	EG11952
Length:	488 (403)
Sequences:	18224 (13829)
Seq/√Len:	688.8

ECOLI - MDTP MDTQ CUSC TOLC

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
76_T	190_V	3.063	1.00
318_V	380_S	2.721	1.00
75_R	269_A	2.718	1.00
222_Q	226_A	2.594	1.00
222_Q	239_R	2.576	1.00
215_D	246_D	2.567	1.00
208_E	253_K	2.441	1.00
208_E	249_I	2.415	1.00
423_R	454_E	2.291	1.00
92_K	379_A	2.266	1.00
88_L	378_A	2.221	1.00
85_E	386_R	2.220	1.00
439_S	442_Q	2.165	1.00
89_R	382_M	2.161	1.00
430_E	434_Q	2.137	1.00
96_Q	375_G	2.134	1.00
201_Y	256_I	2.134	1.00
82_T	389_Q	2.120	1.00
97_A	172_H	2.117	1.00
424_F	427_R	2.079	1.00
178_E	306_A	2.063	1.00
232_Q	424_F	2.058	1.00
204_L	253_K	2.043	1.00
95_S	371_A	2.026	1.00
229_L	437_L	2.017	1.00
167_A	317_Q	1.988	1.00
211_H	249_I	1.971	1.00
243_L	246_D	1.950	1.00
225_V	235_F	1.948	1.00
223_S	431_A	1.924	1.00
203_M	455_M	1.918	1.00
202_Q	205_D	1.915	1.00
325_F	373_L	1.904	1.00
216_Y	219_K	1.903	1.00
74_Q	78_S	1.878	1.00
416_A	457_L	1.848	1.00
215_D	242_I	1.843	1.00
170_G	309_W	1.822	1.00
211_H	242_I	1.819	1.00
177_A	305_Q	1.809	1.00
197_M	256_I	1.808	1.00
409_N	464_R	1.785	1.00
315_L	380_S	1.761	1.00
211_H	246_D	1.759	1.00
204_L	256_I	1.756	1.00
457_L	461_D	1.746	1.00
68_Q	71_A	1.742	1.00
379_A	382_M	1.729	1.00
200_S	259_T	1.715	1.00
204_L	249_I	1.703	1.00
423_R	427_R	1.691	1.00
308_R	387_Y	1.677	1.00
84_A	385_E	1.651	1.00
90_E	179_T	1.647	1.00
243_L	417_E	1.646	1.00
116_R	143_T	1.642	1.00
199_A	462_S	1.638	1.00
332_K	356_I	1.630	1.00
215_D	219_K	1.630	1.00
174_A	310_Y	1.612	1.00
171_A	313_A	1.606	1.00
218_V	239_R	1.580	1.00
329_F	359_L	1.578	1.00
192_Q	466_I	1.574	1.00
200_S	252_V	1.565	1.00
171_A	317_Q	1.565	1.00
365_D	369_L	1.551	1.00
163_S	166_A	1.541	1.00
73_I	187_A	1.540	1.00
389_Q	393_N	1.521	1.00
256_I	260_R	1.513	1.00
199_A	458_L	1.510	1.00
408_L	460_L	1.507	1.00
160_V	328_S	1.501	1.00
309_W	312_Q	1.496	1.00
225_V	232_Q	1.496	1.00
396_R	400_V	1.490	1.00
218_V	222_Q	1.485	1.00
99_L	375_G	1.482	1.00
236_H	424_F	1.482	1.00
311_V	387_Y	1.480	1.00
218_V	242_I	1.480	1.00
71_A	74_Q	1.475	1.00
173_N	176_L	1.473	1.00
387_Y	391_V	1.459	1.00
209_Q	454_E	1.455	1.00
318_V	373_L	1.453	1.00
450_V	454_E	1.445	1.00
250_V	410_D	1.442	1.00
72_L	190_V	1.441	1.00
192_Q	470_Q	1.436	1.00
164_A	320_S	1.430	1.00
177_A	180_A	1.429	1.00
311_V	384_I	1.428	1.00
312_Q	315_L	1.421	1.00
97_A	169_I	1.416	1.00
88_L	385_E	1.415	1.00
212_D	216_Y	1.414	1.00
92_K	382_M	1.407	1.00
104_S	165_V	1.406	1.00
204_L	208_E	1.406	1.00
88_L	381_N	1.404	1.00
209_Q	212_D	1.399	1.00
380_S	384_I	1.398	1.00
191_A	469_I	1.389	1.00
381_N	384_I	1.383	1.00
203_M	459_M	1.374	1.00
67_P	72_L	1.371	1.00
91_E	94_Q	1.370	1.00
89_R	92_K	1.367	1.00
249_I	253_K	1.364	1.00
408_L	467_Q	1.358	1.00
75_R	267_I	1.345	1.00
431_A	434_Q	1.341	1.00
306_A	310_Y	1.339	1.00
412_R	457_L	1.335	1.00
382_M	386_R	1.327	1.00
174_A	313_A	1.320	1.00
242_I	246_D	1.306	1.00
70_D	74_Q	1.303	1.00
227_H	435_R	1.299	1.00
173_N	309_W	1.295	1.00
95_S	374_E	1.294	1.00
219_K	223_S	1.294	1.00
197_M	260_R	1.292	1.00
429_A	438_T	1.283	1.00
166_A	316_D	1.282	1.00
307_M	383_M	1.282	1.00
77_L	187_A	1.277	1.00
180_A	183_E	1.269	1.00
214_I	245_V	1.267	1.00
175_A	178_E	1.265	1.00
167_A	320_S	1.264	1.00
223_S	226_A	1.263	1.00
388_N	391_V	1.261	1.00
419_V	457_L	1.258	1.00
316_D	319_D	1.253	1.00
201_Y	260_R	1.251	1.00
85_E	385_E	1.247	1.00
205_D	209_Q	1.244	1.00
239_R	417_E	1.243	1.00
430_E	447_R	1.239	1.00
318_V	377_R	1.237	1.00
452_A	456_S	1.237	1.00
90_E	176_L	1.235	1.00
375_G	379_A	1.230	1.00
181_A	185_S	1.230	1.00
88_L	91_E	1.227	1.00
417_E	420_E	1.222	1.00
211_H	215_D	1.221	1.00
426_Q	430_E	1.220	1.00
205_D	208_E	1.220	1.00
265_A	396_R	1.217	1.00
416_A	420_E	1.216	1.00
372_N	375_G	1.215	1.00
170_G	312_Q	1.213	1.00
405_L	464_R	1.209	1.00
73_I	77_L	1.205	1.00
96_Q	99_L	1.200	1.00
258_E	404_R	1.200	1.00
196_S	466_I	1.196	1.00
426_Q	450_V	1.195	1.00
419_V	454_E	1.194	1.00
177_A	309_W	1.190	1.00
261_E	400_V	1.186	1.00
413_E	417_E	1.184	1.00
99_L	372_N	1.183	1.00
87_K	179_T	1.180	1.00
75_R	79_G	1.170	1.00
459_M	463_R	1.165	1.00
207_L	245_V	1.164	1.00
416_A	461_D	1.163	1.00
427_R	431_A	1.163	1.00
97_A	101_D	1.160	1.00
190_V	263_L	1.160	1.00
236_H	239_R	1.158	1.00
423_R	450_V	1.156	1.00
199_A	459_M	1.156	1.00
208_E	212_D	1.153	1.00
73_I	191_A	1.150	1.00
250_V	253_K	1.148	1.00
419_V	450_V	1.147	1.00
432_A	438_T	1.146	1.00
322_R	373_L	1.145	1.00
212_D	215_D	1.141	1.00
95_S	378_A	1.140	1.00
445_E	448_L	1.138	1.00
232_Q	236_H	1.135	1.00
219_K	222_Q	1.133	1.00
240_A	422_T	1.131	1.00
98_D	371_A	1.130	1.00
156_D	159_G	1.123	1.00
374_E	377_R	1.118	1.00
433_Y	440_R	1.109	1.00
368_R	372_N	1.107	1.00
94_Q	172_H	1.106	1.00
114_L	145_A	1.105	1.00
222_Q	235_F	1.103	1.00
188_T	473_K	1.101	1.00
218_V	235_F	1.097	1.00
170_G	173_N	1.096	1.00
189_G	192_Q	1.090	1.00
84_A	87_K	1.090	1.00
258_E	403_T	1.088	1.00
364_F	367_G	1.085	1.00
77_L	183_E	1.082	1.00
376_T	379_A	1.081	1.00
301_R	474_S	1.079	1.00
179_T	183_E	1.077	1.00
161_H	165_V	1.072	1.00
163_S	316_D	1.071	1.00
332_K	358_G	1.068	1.00
91_E	381_N	1.067	1.00
69_L	191_A	1.067	1.00
369_L	373_L	1.066	1.00
241_Q	244_A	1.062	1.00
334_F	354_N	1.059	1.00
311_V	380_S	1.059	1.00
181_A	303_D	1.059	1.00
170_G	316_D	1.058	1.00
185_S	189_G	1.055	1.00
90_E	172_H	1.054	1.00
102_A	368_R	1.052	1.00
76_T	186_L	1.046	1.00
87_K	91_E	1.042	1.00
206_L	458_L	1.041	1.00
178_E	310_Y	1.041	1.00
310_Y	386_R	1.039	1.00
81_H	385_E	1.022	1.00
71_A	75_R	1.020	1.00
464_R	468_S	1.019	1.00
86_A	182_V	1.017	1.00
308_R	312_Q	1.008	1.00
72_L	267_I	1.007	1.00
468_S	472_M	1.006	1.00
325_F	369_L	1.005	1.00
154_D	157_L	1.003	1.00
193_L	259_T	1.002	1.00
221_H	230_E	1.001	1.00
243_L	421_A	0.998	1.00
411_E	463_R	0.992	1.00
204_L	252_V	0.991	1.00
239_R	243_L	0.990	1.00
83_L	186_L	0.986	1.00
202_Q	461_D	0.986	1.00
419_V	423_R	0.984	1.00
385_E	388_N	0.984	1.00
373_L	377_R	0.981	1.00
412_R	464_R	0.972	1.00
248_Q	251_A	0.967	1.00
257_T	403_T	0.964	1.00
335_F	351_R	0.961	1.00
304_L	394_A	0.961	1.00
188_T	469_I	0.960	1.00
307_M	390_S	0.959	1.00
305_Q	308_R	0.959	1.00
95_S	98_D	0.958	1.00
410_D	413_E	0.953	1.00
251_A	255_Q	0.952	1.00
114_L	143_T	0.950	1.00
325_F	370_N	0.947	1.00
438_T	442_Q	0.945	1.00
195_Y	469_I	0.945	1.00
409_N	413_E	0.944	1.00
431_A	435_R	0.942	1.00
254_G	404_R	0.939	1.00
383_M	386_R	0.938	1.00
207_L	252_V	0.937	1.00
172_H	176_L	0.935	1.00
321_A	324_L	0.933	1.00
420_E	423_R	0.932	1.00
111_L	148_G	0.931	1.00
314_S	376_T	0.928	1.00
224_K	230_E	0.926	1.00
462_S	466_I	0.925	1.00
461_D	465_V	0.922	1.00
254_G	407_T	0.919	1.00
233_V	429_A	0.914	1.00
253_K	410_D	0.913	1.00
406_Q	410_D	0.912	1.00
180_A	305_Q	0.907	1.00
163_S	319_D	0.906	1.00
99_L	371_A	0.905	1.00
168_A	171_A	0.904	1.00
301_R	397_D	0.903	1.00
308_R	391_V	0.901	1.00
225_V	230_E	0.901	1.00
250_V	414_M	0.898	1.00
196_S	262_S	0.897	1.00
317_Q	321_A	0.896	1.00
254_G	258_E	0.895	1.00
415_Q	460_L	0.889	1.00
88_L	382_M	0.888	1.00
412_R	416_A	0.888	1.00
235_F	239_R	0.887	1.00
470_Q	473_K	0.882	1.00
167_A	171_A	0.881	1.00
101_D	165_V	0.880	1.00
265_A	389_Q	0.878	1.00
162_R	166_A	0.878	1.00
202_Q	458_L	0.875	1.00
251_A	411_E	0.874	1.00
301_R	394_A	0.873	1.00
197_M	201_Y	0.872	1.00
393_N	397_D	0.872	1.00
91_E	378_A	0.870	1.00
200_S	203_M	0.870	1.00
241_Q	448_L	0.870	1.00
184_L	302_P	0.867	1.00
104_S	162_R	0.866	1.00
317_Q	320_S	0.863	1.00
185_S	473_K	0.863	1.00
239_R	421_A	0.862	1.00
314_S	317_Q	0.857	1.00
422_T	453_E	0.854	1.00
307_M	310_Y	0.852	1.00
260_R	264_R	0.851	1.00
377_R	381_N	0.851	1.00
223_S	227_H	0.849	1.00
237_G	445_E	0.847	1.00
324_L	372_N	0.846	1.00
104_S	161_H	0.846	1.00
87_K	183_E	0.844	1.00
165_V	169_I	0.844	1.00
402_G	406_Q	0.841	1.00
100_L	168_A	0.840	1.00
97_A	165_V	0.838	1.00
230_E	234_P	0.835	1.00
420_E	424_F	0.831	1.00
412_R	460_L	0.831	1.00
257_T	260_R	0.827	1.00
246_D	414_M	0.826	1.00
211_H	245_V	0.826	1.00
109_A	365_D	0.825	1.00
398_V	471_L	0.824	1.00
412_R	461_D	0.821	1.00
401_N	467_Q	0.820	1.00
221_H	238_A	0.820	1.00
207_L	249_I	0.820	1.00
81_H	392_L	0.817	1.00
321_A	376_T	0.816	1.00
296_E	299_A	0.809	1.00
247_K	411_E	0.808	1.00
362_P	365_D	0.807	1.00
163_S	320_S	0.805	1.00
386_R	390_S	0.802	1.00
72_L	263_L	0.802	1.00
303_D	394_A	0.801	1.00
197_M	259_T	0.798	1.00
318_V	322_R	0.797	1.00
186_L	190_V	0.796	1.00
193_L	266_L	0.795	1.00
105_Q	366_G	0.795	1.00
445_E	449_P	0.794	1.00
244_A	418_R	0.793	1.00
214_I	238_A	0.791	1.00
203_M	207_L	0.790	1.00
298_L	395_V	0.790	1.00
411_E	415_Q	0.789	1.00
236_H	421_A	0.788	1.00
108_V	151_A	0.787	1.00
105_Q	364_F	0.782	1.00
255_Q	259_T	0.781	1.00
102_A	366_G	0.781	1.00
195_Y	462_S	0.777	1.00
395_V	399_A	0.776	1.00
93_A	175_A	0.774	1.00
413_E	416_A	0.773	1.00
297_L	398_V	0.772	1.00
188_T	470_Q	0.768	1.00
231_A	234_P	0.767	1.00
319_D	322_R	0.767	1.00
335_F	353_F	0.765	1.00
244_A	456_S	0.764	1.00
85_E	389_Q	0.763	1.00
311_V	315_L	0.763	1.00
216_Y	430_E	0.763	1.00
85_E	382_M	0.763	1.00
378_A	381_N	0.762	1.00
85_E	89_R	0.762	1.00
207_L	248_Q	0.756	1.00
304_L	387_Y	0.756	1.00
261_E	399_A	0.753	1.00
404_R	470_Q	0.752	1.00
264_R	269_A	0.749	1.00
408_L	411_E	0.749	1.00
192_Q	196_S	0.748	1.00
324_L	369_L	0.745	1.00
379_A	383_M	0.743	1.00
315_L	319_D	0.741	1.00
163_S	323_A	0.740	1.00
110_A	361_L	0.739	1.00
84_A	388_N	0.738	1.00
253_K	257_T	0.737	1.00
426_Q	447_R	0.735	1.00
154_D	330_D	0.735	1.00
191_A	472_M	0.735	1.00
405_L	468_S	0.735	1.00
313_A	317_Q	0.735	1.00
92_K	96_Q	0.733	1.00
243_L	414_M	0.731	1.00
406_Q	409_N	0.730	1.00
237_G	442_Q	0.726	1.00
401_N	474_S	0.726	1.00
62_K	70_D	0.722	1.00
152_G	330_D	0.721	1.00
177_A	302_P	0.720	1.00
258_E	400_V	0.720	1.00
224_K	229_L	0.718	1.00
304_L	391_V	0.717	1.00
98_D	374_E	0.714	1.00
388_N	392_L	0.714	1.00
169_I	173_N	0.713	1.00
200_S	256_I	0.713	1.00
210_T	214_I	0.713	1.00
262_S	396_R	0.711	1.00
305_Q	309_W	0.709	1.00
200_S	255_Q	0.709	1.00
386_R	389_Q	0.708	1.00
405_L	409_N	0.707	1.00
465_V	468_S	0.706	1.00
181_A	306_A	0.706	1.00
456_S	459_M	0.704	1.00
216_Y	220_A	0.704	1.00
92_K	378_A	0.702	1.00
269_A	273_D	0.701	1.00
203_M	255_Q	0.701	1.00
76_T	267_I	0.700	1.00
166_A	169_I	0.698	1.00
167_A	313_A	0.695	1.00
405_L	471_L	0.693	1.00
61_W	70_D	0.692	1.00
81_H	388_N	0.690	1.00
247_K	415_Q	0.690	1.00
427_R	430_E	0.690	1.00
418_R	422_T	0.689	1.00
160_V	164_A	0.686	1.00
295_Y	299_A	0.685	1.00
390_S	393_N	0.685	1.00
160_V	323_A	0.684	1.00
330_D	358_G	0.683	1.00
94_Q	176_L	0.679	1.00
314_S	383_M	0.679	1.00
171_A	174_A	0.679	1.00
206_L	455_M	0.674	1.00
189_G	193_L	0.672	1.00
196_S	259_T	0.672	1.00
244_A	248_Q	0.671	1.00
370_N	374_E	0.670	1.00
157_L	161_H	0.670	1.00
196_S	200_S	0.669	1.00
113_M	146_T	0.669	1.00
154_D	161_H	0.667	1.00
176_L	180_A	0.666	1.00
174_A	178_E	0.665	1.00
83_L	183_E	0.663	1.00
75_R	78_S	0.661	1.00
404_R	467_Q	0.660	1.00
236_H	428_A	0.659	1.00
148_G	334_F	0.658	1.00
112_G	147_V	0.655	1.00
296_E	300_R	0.654	1.00
82_T	85_E	0.654	1.00
261_E	403_T	0.654	1.00
208_E	211_H	0.654	1.00
384_I	388_N	0.652	1.00
199_A	203_M	0.651	1.00
207_L	455_M	0.650	1.00
328_S	360_K	0.650	1.00
407_T	410_D	0.648	1.00
217_A	440_R	0.647	1.00
110_A	149_L	0.646	1.00
156_D	326_Y	0.643	1.00
259_T	262_S	0.639	1.00
408_L	463_R	0.639	1.00
73_I	190_V	0.637	1.00
225_V	231_A	0.637	1.00
246_D	417_E	0.634	1.00
315_L	384_I	0.632	1.00
377_R	380_S	0.631	1.00
333_A	355_F	0.627	1.00
365_D	368_R	0.625	1.00
432_A	437_L	0.625	1.00
317_Q	379_A	0.624	1.00
80_S	266_L	0.624	1.00
214_I	241_Q	0.624	1.00
298_L	391_V	0.622	1.00
90_E	94_Q	0.620	1.00
441_L	445_E	0.620	1.00
442_Q	445_E	0.619	1.00
369_L	372_N	0.618	1.00
233_V	428_A	0.616	1.00
237_G	241_Q	0.616	1.00
253_K	407_T	0.614	1.00
101_D	105_Q	0.610	1.00
116_R	141_Y	0.609	1.00
157_L	330_D	0.608	1.00
367_G	371_A	0.608	1.00
463_R	467_Q	0.607	1.00
183_E	187_A	0.603	1.00
92_K	375_G	0.602	1.00
83_L	179_T	0.602	1.00
255_Q	258_E	0.602	1.00
86_A	89_R	0.601	1.00
333_A	353_F	0.600	1.00
422_T	449_P	0.597	1.00
424_F	428_A	0.597	1.00
182_V	185_S	0.597	1.00
307_M	387_Y	0.595	1.00
240_A	425_T	0.593	1.00
178_E	181_A	0.591	1.00
174_A	306_A	0.591	1.00
160_V	324_L	0.591	1.00
196_S	199_A	0.590	1.00
81_H	268_G	0.590	1.00
425_T	446_A	0.586	1.00
467_Q	470_Q	0.586	1.00
111_L	150_F	0.584	1.00
294_S	395_V	0.584	1.00
381_N	385_E	0.583	1.00
188_T	192_Q	0.583	1.00
252_V	255_Q	0.581	1.00
314_S	380_S	0.580	1.00
199_A	463_R	0.580	1.00
81_H	389_Q	0.580	1.00
164_A	167_A	0.578	1.00
150_F	334_F	0.576	1.00
262_S	400_V	0.575	1.00
414_M	417_E	0.574	1.00
321_A	372_N	0.572	1.00
374_E	378_A	0.571	1.00
371_A	374_E	0.567	1.00
449_P	452_A	0.566	1.00
429_A	446_A	0.565	1.00
109_A	362_P	0.564	1.00
226_A	434_Q	0.564	1.00
317_Q	376_T	0.563	1.00
393_N	396_R	0.561	1.00
158_W	326_Y	0.560	1.00
219_K	427_R	0.559	1.00
198_Q	201_Y	0.558	1.00
154_D	160_V	0.558	1.00
166_A	170_G	0.555	1.00
400_V	404_R	0.555	1.00
155_L	331_I	0.554	1.00
428_A	432_A	0.553	1.00
310_Y	314_S	0.550	1.00
207_L	211_H	0.549	1.00
220_A	224_K	0.549	1.00
206_L	451_L	0.547	1.00
408_L	464_R	0.544	1.00
98_D	101_D	0.542	1.00
448_L	452_A	0.542	1.00
250_V	254_G	0.542	1.00
198_Q	202_Q	0.540	1.00
415_Q	456_S	0.540	1.00
426_Q	443_A	0.537	1.00
463_R	466_I	0.537	1.00
218_V	238_A	0.537	1.00
341_H	344_T	0.536	1.00
315_L	318_V	0.536	1.00
157_L	329_F	0.536	1.00
79_G	268_G	0.536	1.00
93_A	96_Q	0.535	1.00
89_R	178_E	0.534	1.00
399_A	403_T	0.533	1.00
297_L	394_A	0.532	1.00
67_P	75_R	0.531	1.00
430_E	443_A	0.530	1.00
203_M	252_V	0.529	1.00
390_S	394_A	0.525	1.00
84_A	88_L	0.525	1.00
190_V	266_L	0.524	1.00
274_M	277_I	0.524	1.00
103_G	161_H	0.523	1.00
265_A	393_N	0.523	1.00
329_F	357_P	0.522	1.00
215_D	218_V	0.521	1.00
91_E	95_S	0.521	1.00
403_T	407_T	0.521	1.00
233_V	425_T	0.519	1.00
359_L	362_P	0.518	0.99
182_V	186_L	0.518	0.99
224_K	234_P	0.518	0.99
193_L	263_L	0.517	0.99
246_D	410_D	0.517	0.99
397_D	400_V	0.516	0.99
95_S	375_G	0.516	0.99
264_R	270_G	0.515	0.99
88_L	92_K	0.514	0.99
293_L	475_L	0.510	0.99
415_Q	453_E	0.510	0.99
186_L	266_L	0.510	0.99
247_K	414_M	0.509	0.99
96_Q	171_A	0.508	0.99
107_Q	365_D	0.508	0.99
221_H	225_V	0.506	0.99
158_W	323_A	0.504	0.99
213_V	447_R	0.503	0.99
296_E	477_G	0.503	0.99
110_A	363_L	0.503	0.99
148_G	336_G	0.501	0.99
438_T	443_A	0.501	0.99
419_V	453_E	0.500	0.99

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4mt4A	3	0.9324	100	0.218	Contact Map
3d5kA	3	0.9201	100	0.23	Contact Map
4mt0A	3	0.9057	100	0.236	Contact Map
4k7rA	3	0.875	100	0.237	Contact Map
1yc9A	3	0.8402	100	0.239	Contact Map
1ek9A	3	0.832	100	0.296	Contact Map
4tkoB	1	0.3525	80	0.939	Contact Map
4dk0A	5	0.3197	46.6	0.952	Contact Map
3fppA	3	0.3053	39.6	0.954	Contact Map
2f1mA	2	0.2787	32.4	0.956	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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